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Anti-metastatic
Views 2761
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Abstracts
Focused Research Topics
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337 Substances Researched for Anti-metastatic
Name
AC
CK
Focus
Curcumin
90
117
Ginsenosides
31
43
EGCG (Epigallocatechin gallate)
18
32
Thymoquinone
27
31
Resveratrol
23
30
Quercetin
16
24
Apigenin
12
21
Melatonin
15
21
Berberine
17
20
Polyphenols
15
20
Flavonoids
11
19
Huaier (Trametes robiniophila murr)
15
19
Luteolin
13
19
Shikonin
11
18
Sulforaphane
15
18
Honokiol
13
17
Vitamin C
11
17
Baicalein
15
16
Cannabidiol
11
16
Delta-tetrahydrocannabinol (THC)
9
15
Fucoidan
12
15
Reishi Mushroom
9
15
Blueberry
7
14
Bromelain
3
13
Cannabinoids
11
13
Pterostilbene
7
13
Selenium
4
13
Cannabis
7
12
Kaempferol
6
12
Pineapple
2
12
Cucurbitacin B
10
11
Green Tea
7
11
Bisdemethoxycurcumin
6
10
Cannabinoids: Synthetic
6
10
Deguelin
9
10
Nobiletin
8
10
Gingerol
8
9
Myricetin
4
9
Paeoniflorin
7
9
Piperlongumine
6
9
Pomegranate
7
9
Zerumbone
4
9
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
3
8
Fisetin
6
8
Garlic
4
8
Genistein
6
8
Ginger
8
8
Parthenolide
3
8
Vitamin D
8
8
Wogonin
7
8
Apple Polyphenols
3
7
Astragaloside
6
7
Betulinic acid
5
7
Catechin
6
7
Ellagic Acid
4
7
Emodin
5
7
Ginseng
2
7
Piperine
3
7
Stilbenes
3
7
Artemisinin
5
6
Beta-Elemene
5
6
Cordyceps Militaris
2
6
Fucoxanthin
2
6
Ginkgo biloba
4
6
Lycopene
4
6
Magnolol
4
6
Mangiferin
5
6
Orange: Mandarin
2
6
Phloretin
2
6
Piceatannol
5
6
Theanine
4
6
6-Shogaol
4
5
Andrographis
4
5
Anthocyanins
5
5
Arctigenin
5
5
Benzyl isothiocyanate
5
5
Black Raspberry
1
5
Crocin
4
5
Dandelion
4
5
Feverfew
1
5
Ginseng (Korean)
4
5
Holy Basil
3
5
Naringenin
5
5
Nigella sativa (aka Black Seed)
4
5
Oridonin
1
5
Panax Notoginseng
4
5
Phenethyl isothiocyanate
5
5
Prunella vulgaris
5
5
Puerarin
4
5
Silibinin
5
5
Tangeretin
3
5
Tanshinone IIA
5
5
Turmeric
4
5
Verbascoside
4
5
Allicin
3
4
Carrot
3
4
Cucurbitacin E
3
4
Gold (nanoparticles)
3
4
Isoliquiritigenin
3
4
Isothiocyanates
4
4
Lysine
2
4
MSM (Methylsulfonylmethane)
3
4
Mistletoe
2
4
Proline
2
4
Sea Cucumber
2
4
Tomato
3
4
Ursolic Acid
4
4
Xanthohumol
4
4
Aloe Vera
2
3
Amygdalin
3
3
Antineoplaston A5
1
3
Antineoplastons
1
3
Astaxanthin
2
3
Berbamine
2
3
Bergamot orange
2
3
Burdock
3
3
Caffeic acid phenethyl ester
2
3
Chrysin
3
3
DHA (Docosahexaenoic Acid)
2
3
Demethoxycurcumin
3
3
Diosgenin
3
3
False Black Pepper
3
3
Ferulic acid
3
3
Fig
2
3
Fish Oil
2
3
Folate
2
3
Germanium
2
3
Hesperidin
2
3
Homeopathic Medicine: All
2
3
Lithospermum erythrorhizon
2
3
Lotus
3
3
Maitake Mushroom
2
3
Manuka Honey
3
3
Medicinal Mushrooms
2
3
Oleuropein
3
3
Peach
2
3
Phyllanthus amarus
3
3
Phyllanthus niruri (Stonebreaker)
3
3
Phyllanthus urinaria
3
3
Pine Bark Extract
3
3
Pomegranate Peel
3
3
Rhubarb
3
3
S-Adenosylmethionine (SAMe)
2
3
Strawberry
2
3
Sweet Potato
2
3
Tocotrienol: Delta
3
3
Trichosanthes Kirilowii
2
3
Vanillin
3
3
Vitamin E
3
3
Adlay
2
2
Alpha-Lipoic Acid
2
2
Amla Fruit
1
2
Apple Pectin
1
2
Ashwagandha
2
2
Asparagus
2
2
Baking Soda
1
2
Bamboo
1
2
Bee Propolis
1
2
Bee Venom
2
2
Bifidobacterium Longum
1
2
Bitter Melon
1
2
Black Pepper
1
2
Boswellia
1
2
Broccoli
1
2
Bufalin
2
2
Cabbage
1
2
Caffeic Acid
2
2
Chaga Mushroom (Inonotus obliquus)
2
2
Chinese Skullcap
2
2
Chlorogenic Acid
1
2
Cinnamaldehyde
2
2
Cloudberry
1
2
Coffee
2
2
Coleus Forskohlii
1
2
Collards
1
2
Coptis chinensis
2
2
Crocetin
2
2
Curcumin: Lipidated
1
2
DIM (3,3'-diindolylmethane)
1
2
Delphinidin
2
2
EPA (Eicosapentaenoic Acid)
1
2
Endocannabinoids
2
2
Essential Oils: Unspecified
1
2
Fenugreek
1
2
Fermented Foods and Beverages
1
2
Flaxseed
2
2
Frankincense
2
2
Gac
2
2
Gallic Acid
1
2
Genipin
2
2
Goji
2
2
Grape
2
2
Hibiscus sabdariffa
1
2
Hops
2
2
Ketone Bodies
1
2
Lactobacillus casei
1
2
Ligustrazine
2
2
Litchi
1
2
Long Pepper
1
2
Loquat Leaves
2
2
Mangosteen
1
2
Marigold
2
2
Milk: Fermented
1
2
Mulberry
1
2
Mushrooms: All
1
2
Nordihydroguaiaretic acid (NDGA)
1
2
Onion
2
2
Palash
1
2
Panax Ginseng
2
2
Pantethine
1
2
Phellinus Linteus
1
2
Prickly Pear Cactus
1
2
Psychedelics:All
2
2
Red Sage
2
2
Red Yeast Rice
1
2
Rosemaric Acid
2
2
Rosemary
1
2
Sesamin
1
2
Sophora Flavescens
2
2
St. Johns Wort
2
2
Stearic Acid (stearate)
1
2
Syrian rue
2
2
Tetrahydrocurcumin
2
2
Thistle
2
2
Triptolide
1
2
Venom: Snake
2
2
Vitamin A
2
2
Vitamin K
1
2
Vitamin K2
1
2
Walnut
2
2
4-Shogaol
1
1
African Basil
1
1
Agaricus Blazei
1
1
Amygdalin (laetrile)
1
1
Antrodia camphorata
1
1
Artesunate
1
1
Artichoke
1
1
Basil
1
1
Beans: All
1
1
Berberis amurensis
1
1
Bergamot
1
1
Betaine
1
1
Black Currant
1
1
Cafestol
1
1
Capsaicin
1
1
Catechols
1
1
Chamomile
1
1
Chili pepper
1
1
Chokeberry
1
1
Chrysanthemum Indicum
1
1
Citrus Peel
1
1
Citrus naringin
1
1
Coptidis rhizoma
1
1
Cordyceps sinensis
1
1
Coriandrum sativum
1
1
Cruciferous Vegetables
1
1
Cucurbitacin D
1
1
Curcuminoids
1
1
Curry Leaves
1
1
D-Limonene
1
1
Daisy
1
1
Dracaena draco
1
1
Eggplant
1
1
Epimedium
1
1
Eugenol
1
1
False Daisy
1
1
Fiber
1
1
Fruit: All
1
1
Ganoderma colossum
1
1
Garcinia Mangostana
1
1
Garcinia indica
1
1
Geum japonicum
1
1
Glycyrrhizin
1
1
Grape Seed Extract
1
1
Graviola
1
1
Guggul
1
1
Gynostemma
1
1
Honey
1
1
Hydroxytyrosol
1
1
Icogenin
1
1
Indole-3-Carbinol
1
1
Juniper
1
1
Krill
1
1
Lichens
1
1
Licorice
1
1
Lignans
1
1
Maple Syrup
1
1
Milk Thistle
1
1
Nettle
1
1
Nexrutine (Phellodendrom)
1
1
Olive
1
1
Olive Oil
1
1
Olive leaf extract
1
1
P-Coumaric Acid
1
1
Palm Oil
1
1
Papaya
1
1
Parsley
1
1
Passion Flower
1
1
Phytoalexins
1
1
Pine Needle
1
1
Plum
1
1
Poria cocos
1
1
Potato
1
1
Probiotics
1
1
Punicalagin
1
1
Punicic acid
1
1
Purslane
1
1
Raspberry
1
1
Rheum palmatum
1
1
Rice Bran
1
1
Rice: Black
1
1
Rose
1
1
Rosmarinic acid
1
1
Rutin
1
1
Saffron
1
1
Schisandra
1
1
Seaweed
1
1
Seaweed: Brown
1
1
Sodium Bicarbonate
1
1
Spirulina
1
1
Tabebuia
1
1
Tannic Acid
1
1
Tea
1
1
Theaflavins
1
1
Tocotrienols
1
1
Tomatidine
1
1
Toona sinensis
1
1
Turmerones
1
1
Urolithin A
1
1
Vegetables: All
1
1
Water: Deep Sea
1
1
Water: Deuterium Depleted
1
1
Water: Electrolyzed Reduced
1
1
White Mulberry
1
1
Wormwood
1
1
beta-Carotene
1
1
β-ionone
1
1
Research Articles
927
Cumulative Knowledge Score
1499
Overall Research Rating
EXCELLENT
View the Evidence:
1433 Abstracts with Anti-metastatic Research
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[+]
A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID:
31929811
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
,
Esophageal Cancer
,
Gastric Cancer
,
Liver Cancer
,
Pancreatic Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
"Although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with BRCA-WT."
Dec 31, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cancer. 2005 ;5:70. Epub 2005 Jul 4. PMID:
15996267
Article Published Date
: Dec 31, 2004
Study Type
: Human Study
Additional Links
Diseases
:
BRCA1/BRCA2: Prevalence
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
BRCA MYTH
[+]
Bromelain has antimetastic protential as demonstrated in lung cancer cells - Article 1.
Jan 01, 1988
Click here to read the entire abstract
Pubmed Data
: J Cancer Res Clin Oncol. 1988;114(5):507-8. PMID:
3182910
Article Published Date
: Jan 01, 1988
Study Type
: Human Study
Additional Links
Substances
:
Bromelain
,
Pineapple
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
FOLFIRI and FOLFOX6 chemotherapies result in a median progression free survival time of between 7.7 and 8.4 months.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Jpn J Clin Oncol. 2010 Jul;40(7):634-8. PMID:
20587616
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Drug: 5-flourouracil
Anti Therapeutic Actions
:
Chemotherapy
[+]
High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.
Jan 06, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 12 7 ;7(1):17188. Epub 2017 Dec 7. PMID:
29215048
Article Published Date
: Jan 06, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.
Feb 01, 2012
Click here to read the entire abstract
Pubmed Data
: Curr Mol Med. 2012 Feb 1 ;12(2):163-76. PMID:
22280355
Article Published Date
: Feb 01, 2012
Study Type
: Human Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Radiosensitizer
Additional Keywords
:
Drug Synergy
[+]
These results indicate that whey protein concentrate might deplete tumour cells of glutathione and render them more vulnerable to chemotherapy.
Oct 31, 1995
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 1995 Nov-Dec;15(6B):2643-9. PMID:
8669840
Article Published Date
: Oct 31, 1995
Study Type
: Human Study
Additional Links
Substances
:
Whey
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
[+]
These results suggest a preventive effect of selenium on prostate cancer progression rather than on prostate cancer development.
Jan 05, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Jan 6. Epub 2017 Jan 6. PMID:
28076331
Article Published Date
: Jan 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Selenium
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.
Oct 27, 2014
Click here to read the entire abstract
Pubmed Data
: Microvasc Res. 2014 Oct 28 ;97C:167-180. Epub 2014 Oct 28. PMID:
25446010
Article Published Date
: Oct 27, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Black Raspberry
Pharmacological Actions
:
Anti-Angiogenic
,
anti-inflammatory
,
Anti-metastatic
,
Anti-Tumor
,
Anticarcinogenic Agents
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Epigenetic Modification
,
Plant Extracts
[+]
An extract of G. lucidum spores suppressed cholangiocarcinoma migration in vitro through inhibition of TGF-β1-induced EMT.
May 14, 2016
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2016 May 15 ;23(5):491-7. Epub 2016 Mar 3. PMID:
27064008
Article Published Date
: May 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Cancer Metastasis
,
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Plant Extracts
[+]
Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.
Aug 24, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Aug 25. Epub 2016 Aug 25. PMID:
27569589
Article Published Date
: Aug 24, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Prostate Cancer
,
Prostate Cancer Stem Cells
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apigenin is a novel therapeutic candidate for melanoma.
Feb 13, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb 14. Epub 2017 Feb 14. PMID:
28260058
Article Published Date
: Feb 13, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.
Jan 10, 2015
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2015 11-12;29(6):711-728. PMID:
26546528
Article Published Date
: Jan 10, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Lung Cancer
,
Non-Small-Cell Lung Carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Gene Expression Regulation
[+]
Cannabidiolic acid an active component in the cannabis plant offers potential therapeutic modality in the abrogation of cancer cell migration.
Nov 14, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Lett. 2012 Nov 15 ;214(3):314-9. Epub 2012 Sep 8. PMID:
22963825
Article Published Date
: Nov 14, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabis
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Cordycepin inhibited migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.
Dec 28, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Dec 29 ;41:109-116. Epub 2016 Dec 29. PMID:
28068557
Article Published Date
: Dec 28, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
[+]
Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015;10(12):e0144462. Epub 2015 Dec 10. PMID:
26656720
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Adiponectin Down-Regulation
,
Anti-metastatic
,
Antiproliferative
[+]
Curcumin reduced Akt expression, cell proliferation, and migration in MDA-MB-231 breast cancer cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(1):e0146553. Epub 2016 Jan 11. PMID:
26752181
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Dose Response
[+]
Diallyl disulfide could be a promising anticancer agent for anti-metastatic treatment of esophageal-gastric junction adenocarcinoma in the future.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2018 Feb ;39(2):784-794. Epub 2017 Nov 27. PMID:
29207122
Article Published Date
: Jan 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
NF-kappaB Inhibitor
[+]
Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2016 Oct ;41(10):2728-2751. Epub 2016 Jul 9. PMID:
27394418
Article Published Date
: Sep 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Mandarin juice exerts in vitro antiproliferative effects on anaplastic thyroid carcinoma cells, associated with a reduction of migration.
Sep 11, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Sep 12:1-8. Epub 2015 Sep 12. PMID:
26365817
Article Published Date
: Sep 11, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Orange: Mandarin
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Nanoparticular thymoquinone attenuates angiogenesis and metastasis of triple-negative breast cancer.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Control Release. 2020 Mar 31 ;322:357-374. Epub 2020 Mar 31. PMID:
32243981
Article Published Date
: Mar 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Thymoquinone
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-metastatic
[+]
Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intest Res. 2017 Apr ;15(2):174-181. Epub 2017 Apr 27. PMID:
28522946
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Feverfew
,
Parthenolide
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Jan ;24(1):50-8. Epub 2014 Nov 20. PMID:
25479727
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Piperine
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.
Dec 14, 2016
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2016 Dec 15. Epub 2016 Dec 15. PMID:
28000876
Article Published Date
: Dec 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
MicroRNA modulator
[+]
Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.
Apr 10, 2017
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2017 Apr 11. Epub 2017 Apr 11. PMID:
28401486
Article Published Date
: Apr 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Shikonin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic Synergy: Temozolomide
,
Glioblastoma
,
Shikonin
[+]
Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Expert Opin Ther Targets. 2016 Jan ;20(1):7-18. Epub 2015 Dec 15. PMID:
26568207
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK
,
Anti-metastatic
,
Apoptotic
,
Chemosensitizer
[+]
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID:
30041241
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-cancer
,
Anti-metastatic
,
Anti-Proliferative
,
Cyclooxygenase 2 Inhibitors
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells.
Apr 30, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Invest. 2010 May ;28(4):357-63. PMID:
19916793.
Article Published Date
: Apr 30, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
The apple polyphenol phloretin inhibits colorectal cancer cell growth.
Sep 13, 2016
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2016 Sep 14 ;64(36):6826-37. Epub 2016 Sep 2. PMID:
27538679
Article Published Date
: Sep 13, 2016
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Apple Polyphenols
,
Phloretin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Tumor Suppressor Protein p53 Upregulation
[+]
The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:117. Epub 2015 Apr 14. PMID:
25880988
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Oridonin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
MicroRNA modulator
[+]
These results show that breast cancer stem cells, in both a canine and a human cell lines are responsive to melatonin treatment.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(3):e0150407. Epub 2016 Mar 2. PMID:
26934679
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro, In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Cancer Stem Cells
[+]
Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Apr ;13(4):2397-2402. Epub 2017 Feb 14. PMID:
28454410
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Zerumbone
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
"Antineoplaston A in cancer therapy. (I)."
Jan 01, 1977
Click here to read the entire abstract
Pubmed Data
: Physiol Chem Phys. 1977 ;9(6):485-500. PMID:
275868
Article Published Date
: Jan 01, 1977
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplastons
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
[+]
"Phase I clinical studies of antineoplaston A5 injections."
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1987 ;13 Suppl 1:37-43. PMID:
3569014
Article Published Date
: Jan 01, 1987
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston A5
Diseases
:
Bladder Cancer
,
Breast Cancer
,
Colorectal Cancer
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemopreventive
[+]
Antineoplaston A2 has anticancer effects.
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1987 ;13 Suppl 1:1-11. PMID:
3569010
Article Published Date
: Jan 01, 1987
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Bladder Cancer
,
Breast Cancer
,
Esophageal Cancer
,
Liver Cancer: Metastatic
,
Lung Cancer
,
Mesothelioma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
[+]
Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Surg Today. 2003 ;33(6):448-53. PMID:
12768372
Article Published Date
: Jan 01, 2003
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Colon Cancer
,
Liver Cancer
,
Liver Cancer: Metastatic
,
Liver Metastasis From Colon Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.
Apr 30, 2007
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2007 May ;13(4):443-5. PMID:
17532738
Article Published Date
: Apr 30, 2007
Study Type
: Human: Case Report
Additional Links
Substances
:
Mistletoe
Diseases
:
Cancer Metastasis
,
Liver Cancer: Metastatic
,
Melanoma
,
Skin Cancer
Pharmacological Actions
:
Anti-metastatic
,
Anti-Tumor
,
Antineoplastic Agents
Additional Keywords
:
Plant Extracts
[+]
Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0123478. Epub 2015 May 8. PMID:
25954974
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Targeted delivery of honokiol by zein/hyaluronic acid core-shell nanoparticles to suppress breast cancer growth and metastasis.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2020 Jul 15 ;240:116325. Epub 2020 Apr 28. PMID:
32475585
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
,
Hyaluronic Acid
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
"Anti-metastasis effect of thymoquinone on human pancreatic cancer"
Jul 31, 2011
Click here to read the entire abstract
Pubmed Data
: Yao Xue Xue Bao. 2011 Aug ;46(8):910-4. PMID:
22007514
Article Published Date
: Jul 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
[+]
"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2005 Mar ;13(3):389-95. PMID:
15706406
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Lung Cancer: Metastatic
,
Post-Operative Lung Metastasis of Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
[+]
(-)-Epigallocatechin-3-gallate (EGCG) can inhibit the proliferation and invasiveness and induce apoptosis in nasopharyngeal carcinoma cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2015 ;16(2):2530-58. Epub 2015 Jan 23. PMID:
25625511
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
10-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models.
Aug 05, 2020
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2020 Aug 6. Epub 2020 Aug 6. PMID:
32761561
Article Published Date
: Aug 05, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
10-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo.
Sep 21, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Sep 22 ;8(42):72260-72271. Epub 2017 Aug 10. PMID:
29069785
Article Published Date
: Sep 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Sci. 2019 Jan ;110(1):389-400. Epub 2018 Dec 14. PMID:
30431207
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
[+]
6-Shogaol decreases cancer-induced up-regulation of CCL2 in TADCs, preventing the enhancing effects of TADCs on tumorigenesis and metastatic properties in A549 and MDA-MB-231 cells.
Feb 17, 2015
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2015 Feb 18 ;63(6):1730-8. Epub 2015 Feb 9. PMID:
25621970
Article Published Date
: Feb 17, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Breast Cancer: Triple Negative
,
Lung Cancer
,
Lung Cancer: Prevention
Pharmacological Actions
:
Anti-metastatic
,
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Cancer Stem Cells
[+]
A Huaier polysaccharide reduced metastasis of human hepatocellular carcinoma.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Aug ;36(8):6285-93. Epub 2015 Mar 19. PMID:
25787750
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Dose Response
[+]
A lipid-soluble ginseng extract potently inhibited invasion and migration of B16F10 mouse melanoma cells in a dose-dependent manner.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Jan ;18(1):102-8. PMID:
25354136
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Melanoma
,
Melanoma: Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Dose Response
[+]
A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits angiogenesis of tumor cells.
Dec 01, 2006
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2006 Dec;27(12):2424-33. Epub 2006 Jun 19. PMID:
16142336
Article Published Date
: Dec 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Lysine
,
Proline
,
Vitamin C
Diseases
:
Cancer Metastasis
,
Tumors
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A novel combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy could be used to manage metastatic cancers.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(6):e0127407. Epub 2015 Jun 10. PMID:
26061868
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ketone Bodies
Diseases
:
Cancer Metastasis
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
,
Hyperbaric Treatment
,
Integrative Medicine
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.
Aug 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Aug 8 ;6:30917. Epub 2016 Aug 8. PMID:
27498973
Article Published Date
: Aug 07, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Polyphenols
,
Strawberry
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
Additional Keywords
:
Dose Response
[+]
A polysaccharide from Punica granatum has an inhibitory effect on metastasis.
May 24, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2017 May 25. Epub 2017 May 25. PMID:
28552725
Article Published Date
: May 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cancer Metastasis
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Anti-metastatic
,
Cancer Metastasis
,
Lung Cancer: Metastatic
,
pomegranate
[+]
A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.
Mar 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 18 ;9(3). Epub 2017 Mar 18. PMID:
28335466
Article Published Date
: Mar 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Lysine
,
Proline
,
Quercetin
,
Vitamin C
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
A steroidal derivative from Trigonella foenum graecum L. that induces apoptosis in vitro and in vivo.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Food Drug Anal. 2019 Jan ;27(1):231-239. Epub 2018 May 26. PMID:
30648576
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fenugreek
Diseases
:
Lung Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Apoptotic
[+]
A synthetic cannabinoid inhibited CXCL12-induced migration and invasive properties of breast cancer cells.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(9):e23901. Epub 2011 Sep 7. PMID:
21915267
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Cannabinoid Receptors
,
Synthetic Cannabinoids
[+]
Administration of quercetin at 15mg/kg body weight resulted in a ~70% reduction in tumor growth.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(6):e0157251. Epub 2016 Jun 10. PMID:
27285995
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Catechin
,
Quercetin
,
Resveratrol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
[+]
Allicin inhibits the proliferation and invasion in cholangiocarcinoma.
May 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID:
29794468
Article Published Date
: May 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Aloesin could be a novel therapeutic treatment for ovarian cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anal Cell Pathol (Amst). 2017 ;2017:8158254. Epub 2017 Jun 18. PMID:
28702312
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Altogether these data suggest M1 is an efficient candidate for melanoma therapy.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Homeopathy. 2016 Feb ;105(1):109-18. Epub 2015 Sep 26. PMID:
26828006
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Homeopathic Medicine: All
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
Chemotherapeutic
[+]
Aluminium salts could be environmental breast carcinogens.
Dec 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2016 Dec 15 ;139(12):2781-2790. Epub 2016 Sep 7. PMID:
27541736
Article Published Date
: Dec 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
Problem Substances
:
Aluminum Chloride
[+]
Amauroderma rude could inhibit cancer cell survival and induce apoptosis, also there were fewer and smaller colonies than the untreated cells.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(6):e66504. Epub 2013 Jun 20. PMID:
23840494
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Mushrooms: All
,
Reishi Mushroom
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Glioblastoma
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
Amla extract modulates cancer cells and the tumor microenvironment.
Apr 24, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Apr 25. Epub 2016 Apr 25. PMID:
27129171
Article Published Date
: Apr 24, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Amla Fruit
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
Additional Keywords
:
Tumor Microenvironment
[+]
An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(10):e78061. Epub 2013 Oct 28. PMID:
24205091
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.
Jan 29, 2017
Click here to read the entire abstract
Pubmed Data
: Sci Rep. 2017 Jan 30 ;7:41656. Epub 2017 Jan 30. PMID:
28134352
Article Published Date
: Jan 29, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Litchi
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
,
P21 Activation
Additional Keywords
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
,
Litchi
,
P21 Activation
,
Plant Extracts
,
prostate cancer
[+]
Andrographis paniculata was shown to possess anti-tumor, anti-metastatic and immunomodulatory activities in esophageal cancer cell.
Mar 11, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Mar 12:152886. Epub 2019 Mar 12. PMID:
30910259
Article Published Date
: Mar 11, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Andrographis
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Immunomodulatory
[+]
Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma.
Oct 21, 2019
Click here to read the entire abstract
Pubmed Data
: Melanoma Res. 2019 Oct 22. Epub 2019 Oct 22. PMID:
31651714
Article Published Date
: Oct 21, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Melanoma: Metastasis
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Inflammatory Agents
,
Anti-metastatic
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-metastatic effects of baicalein by targeting STAT3 activity in breast cancer cells.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2020 ;43(12):1899-1905. PMID:
33268707
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Interleukin-6 Downregulation
[+]
Anti-metastatic properties of a potent herbal combination in cell and mice models of triple negative breast cancer.
Feb 14, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Feb 15 ;243:117245. Epub 2020 Jan 8. PMID:
31926253
Article Published Date
: Feb 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
,
Crocin
,
Saffron
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2019 Jan ;17(1):1008-1018. Epub 2018 Nov 15. PMID:
30655860
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
[+]
Anticancer effects of Gleditsia sinensis extract in rats transplanted with hepatocellular carcinoma cells.
Aug 07, 2019
Click here to read the entire abstract
Pubmed Data
: Oncol Res. 2019 Aug 8 ;27(8):889-899. Epub 2019 Apr 2. PMID:
30940289
Article Published Date
: Aug 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gleditsia sinensis
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2019 ;16:49. Epub 2019 Jul 26. PMID:
31372176
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pineapple
,
Vinegar
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.
Nov 11, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2019 Nov 12. Epub 2019 Nov 12. PMID:
31714653
Article Published Date
: Nov 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Magnolol
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Arctigenin attenuates tumor metastasis of hepatocellular carcinoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:937. Epub 2019 Aug 29. PMID:
31555129
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells.
Jan 14, 2011
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2011 Jan 15 ;18(2-3):158-62. Epub 2010 Aug 23. PMID:
20739158
Article Published Date
: Jan 14, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Artemisinin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ascorbate supplementation hinders metastasis, tumor growth and inflammatory cytokine secretion as well as enhanced encapsulation of tumors elicited by melanoma and breast cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2013 Jan ;42(1):55-64. Epub 2012 Nov 21. PMID:
23175106
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Breast Cancer: Triple Negative
,
Inflammation
,
Melanoma
,
Melanoma: Metastasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Antioxidants
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Cytokine Modulation
,
Significant Treatment Outcome
,
Supplementation
[+]
Astaxanthin inhibits liver metastasis of mastocytoma cells in an animal model.
Apr 21, 2002
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2002 Apr 21;70(21):2509-20. PMID:
12173414
Article Published Date
: Apr 21, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Mastocytoma
Pharmacological Actions
:
Anti-metastatic
[+]
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer.
Nov 19, 2020
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2020 Nov 20. Epub 2020 Nov 20. PMID:
33219447
Article Published Date
: Nov 19, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Astragaloside IV inhibits the invasion and metastasis of SiHa cervical cancer cells.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2019 May ;41(5):2975-2986. Epub 2019 Mar 13. PMID:
30896841
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Baicalein has the potential to suppress breast cancer metastasis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2016 ;10:1419-41. Epub 2016 Apr 18. PMID:
27143851
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Wnt/β-catenin pathway down-regulation
[+]
Basil polysaccharide inhibits hypoxia-induced hepatocellular carcinoma metastasis and progression.
Jun 24, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Jun 25 ;137:32-44. Epub 2019 Jun 25. PMID:
31252022
Article Published Date
: Jun 24, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Basil
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Additional Keywords
:
Polysaccharides
[+]
Bee venom and its major constituent melittin might represent a potential therapeutic strategy for increasing the radiation response of solid tumors.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2020 Jan-Dec;19:1534735420944476. PMID:
32735464
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Ehrlich carcinoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
[+]
Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug ;20(2):1808-1818. Epub 2019 Jun 18. PMID:
31257529
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Benzyl isothiocyanate
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Wnt/β-catenin signaling pathway modulation
[+]
Berberine suppresses growth and metastasis of endometrial cancer cells.
Jun 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1287-1293. Epub 2018 May 7. PMID:
29864910
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Prostaglandin PGE2 downregulation
[+]
Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.
Apr 18, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Cancer. 2004 Apr 19 ;90(8):1672-8. PMID:
15083202
Article Published Date
: Apr 18, 2004
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Cancer Metastasis
,
Melanoma
,
Skin Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo.
Mar 18, 2019
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem. 2019 Mar 19. Epub 2019 Mar 19. PMID:
30910472
Article Published Date
: Mar 18, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Betulinic acid induces apoptosis and inhibits metastasis of human renal carcinoma cells in vitro and in vivo.
Jan 10, 2018
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2018 11 ;119(10):8611-8622. Epub 2018 Jun 20. PMID:
29923216
Article Published Date
: Jan 10, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Kidney Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2019 Jan ;23(1):586-595. Epub 2018 Nov 12. PMID:
30417527
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Betulinic acid triggers apoptosis and inhibits migration and invasion of gastric cancer cells by impairing EMT progress.
Apr 12, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Biochem Funct. 2020 Apr 13. Epub 2020 Apr 13. PMID:
32283563
Article Published Date
: Apr 12, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-metastatic
,
Antiproliferative
[+]
Bicarbonate increases tumor pH and inhibits spontaneous metastases.
Mar 14, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Res. 2009 Mar 15 ;69(6):2260-8. Epub 2009 Mar 10. PMID:
19276390
Article Published Date
: Mar 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Baking Soda
Diseases
:
Breast Cancer: Metastatic
,
Cancer-Acidosis Connection
Pharmacological Actions
:
Anti-metastatic
[+]
Biochanin A regulates the growth and migration of NSCLC through suppressing the VEGF/VEGFR2 signaling pathway.
Jul 22, 2018
Click here to read the entire abstract
Pubmed Data
: Oncol Res. 2018 Jul 23. Epub 2018 Jul 23. PMID:
30037363
Article Published Date
: Jul 22, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.
Jan 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2017 Jan 18. Epub 2017 Jan 18. PMID:
28098340
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
,
Fibrosarcoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Blueberry malvidin-3-galactoside suppresses hepatocellular carcinoma.
Jan 15, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Jan 16 ;67(2):625-636. Epub 2019 Jan 7. PMID:
30586992
Article Published Date
: Jan 15, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Blueberry
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Blueberry supresses the growth and metastasis of triple negative breast tumors in animals.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2011 Aug 31. Epub 2011 Aug 31. PMID:
21880954
Article Published Date
: Aug 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Breast Cancer: Metastatic
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
[+]
Boswellic acid inhibits growth and metastasis of human colorectal cancer.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2012 May 1 ;130(9):2176-84. Epub 2011 Sep 12. PMID:
21702037
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
,
Frankincense
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model).
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID:
22066019
Article Published Date
: Jan 01, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Boswellia
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Both ginseng saponins, 20(R)- and 20(S)-ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells.
Aug 31, 1995
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 1995 Sep ;18(9):1197-202. PMID:
8845804
Article Published Date
: Aug 31, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
[+]
Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition in oral squamous cell carcinoma.
Jan 08, 2018
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2018 12 9 ;507(1-4):142-147. Epub 2018 Nov 8. PMID:
30415774
Article Published Date
: Jan 08, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Cancer Metastasis
,
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
[+]
Breast cancer amelioration by Butea monosperma in-vitro and in-vivo.
May 09, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 May 10 ;217:54-62. Epub 2018 Jan 31. PMID:
29366766
Article Published Date
: May 09, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Palash
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Phytotherapy
,
Plant Extracts
,
Selective Cytotoxicity
[+]
Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.
May 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 15. Epub 2016 May 15. PMID:
27191743
Article Published Date
: May 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bee Propolis
,
Caffeic acid phenethyl ester
Diseases
:
Cancer Metastasis
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.
Dec 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Cancer Ther. 2010 Jan ;9(1):180-9. Epub 2010 Jan 6. PMID:
20053780
Article Published Date
: Dec 31, 2009
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Cannabinoid Receptors
,
Natural Substance Synergy
[+]
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
Apr 01, 2012
Click here to read the entire abstract
Pubmed Data
: FASEB J. 2012 Apr ;26(4):1535-48. Epub 2011 Dec 23. PMID:
22198381
Article Published Date
: Apr 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Intracellular adhesion molecule-1 (ICAM-1)
[+]
Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.
Nov 30, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID:
17065222
Article Published Date
: Nov 30, 2006
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
,
Cannabinoids: Synthetic
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
Additional Keywords
:
Cannabinoid Receptors
,
Selective Cytotoxicity
[+]
Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2019 ;9:743. Epub 2019 Aug 8. PMID:
31456939
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carnosol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
CBD can be used as a novel therapeutic option to inhibit growth and metastasis of highly aggressive breast cancer subtypes including TNBC.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Oncol. 2015 Apr ;9(4):906-19. Epub 2015 Jan 19. PMID:
25660577
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Epidermal growth factor receptor (EGFR) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Chemovirotherapy of lung squamous cell carcinoma by combining oncolytic adenovirus with gemcitabine.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Front Oncol. 2020 ;10:229. Epub 2020 Feb 25. PMID:
32158698
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Viruses: Beneficial
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
,
Chemovirotherapy
[+]
Chloroform extracts of Cordyceps taii have potent in vivo antitumor and antimetastatic activities.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:216. Epub 2015 Jul 9. PMID:
26155792
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Medicinal Mushrooms
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Citrus unshiu peel suppress the metastatic potential of murine melanoma B16F10 cells in vitro and in vivo.
Sep 03, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytother Res. 2019 Sep 4. Epub 2019 Sep 4. PMID:
31486124
Article Published Date
: Sep 03, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Satsuma
Diseases
:
Melanoma: Metastasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cloudberry and its compounds possess strong chemopreventive activity against colon cancer.
May 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 30. Epub 2016 May 30. PMID:
27270323
Article Published Date
: May 29, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cloudberry
,
Ellagic Acid
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemopreventive
[+]
Collards and cabbage prevent pulmonary metastasis of mammary cancer in mice.
Jan 01, 1989
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1989;12(2):121-6. PMID:
2710654
Article Published Date
: Jan 01, 1989
Study Type
: Animal Study
Additional Links
Substances
:
Cabbage
,
Collards
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
,
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
[+]
Combined ginsenoside Rg3 and transarterial embolization treatment limited metastasis and promoted survival.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2014 ;7:1945-54. Epub 2014 Oct 21. PMID:
25364265
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Comparable efficacy of fisetin and vemurafenib for inhibiting melanoma growth was noted in this study.
Oct 23, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 Oct 24 ;8(1):15726. Epub 2018 Oct 24. PMID:
30356079
Article Published Date
: Oct 23, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Dec ;16(6):6930-6939. Epub 2018 Sep 27. PMID:
30546425
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Crocin induces autophagic cell death and inhibits cell invasion of cervical cancer SiHa cells through activation of PI3K/AKT.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2020 Sep ;8(18):1180. PMID:
33241029
Article Published Date
: Aug 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Cucurbitacin B inhibited breast cancer metastasis and angiogenesis.
May 18, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Biochem Cell Biol. 2016 May 19 ;77(Pt A):41-56. Epub 2016 May 19. PMID:
27210504
Article Published Date
: May 18, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Cucurbitacin E can be considered to be a promising anti-cancer agent for osteosarcoma.
Sep 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biosci Rep. 2016 Sep 21. Epub 2016 Sep 21. PMID:
27653525
Article Published Date
: Sep 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cucurbitacin E
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Cucurbitacin E inhibits the Yes associated protein signaling pathway and suppresses brain metastasis of human non small cell lung cancer in a murine model.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Rep. 2019 Aug ;42(2):697-707. Epub 2019 Jun 20. PMID:
31233205
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cucurbitacin E
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Curcumin effectively inhibited the proliferation of melanoma cells in vitro and in vivo.
Nov 11, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Nov 12. Epub 2015 Nov 12. PMID:
26573768
Article Published Date
: Nov 11, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Cell cycle arrest
[+]
Curcumin exhibits chemopreventive properties in hematogenous breast cancer metastases in immunodeficient mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2007;19(1-4):137-52. PMID:
17310108
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Cancer Metastasis
,
Immune Disorders: Low Immune Function
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Curcumin inhibited the growth and invasion of human monocytic leukaemia SHI-1 cells.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2020 Dec ;58(1):25-34. PMID:
31854220
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Leukemia: Monocytic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Curcumin inhibits lung cancer cell metastasis.
Jan 01, 2000
Click here to read the entire abstract
Pubmed Data
: Clin Exp Metastasis. 2000;18(7):539-45. PMID:
11688958
Article Published Date
: Jan 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
[+]
Curcumin inhibits lymphangiogenesis in vitro and in vivo, which could contribute to the antimetastatic effects of curcumin.
Aug 26, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2015 Aug 27. Epub 2015 Aug 27. PMID:
26375757
Article Published Date
: Aug 26, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Curcumin may inhibit gastric cancer lymph node metastasis.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Jul ;36(7):5215-23. Epub 2015 Feb 10. PMID:
25874494
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
Curcumin modulates hepatocellular carcinoma by reducing UNC119 expression.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2019 ;38(3):195-203. PMID:
31679307
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Curcumin not only inhibits tumor angiogenesis, but also suppresses the production of VEGF in response to hypoxia.
Aug 13, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2015 Aug 14 ;6(23):19469-82. PMID:
26254223
Article Published Date
: Aug 13, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Curcumin suppressed phthalate-induced cell migration, invasion and epithelial-mesenchymal transition, decreased the proportion of CSC-like cells.
Nov 19, 2015
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID:
26585812
Article Published Date
: Nov 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Liver Cancer
,
Liver Cancer: Metastatic
,
Phthalate Toxicity
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Cancer Stem Cells
Problem Substances
:
Phthalates
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Curcumin-C3complex®/Bioperine® treatment strongly reduces in vitro tumorigenic properties of mesothelioma cells.
Aug 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Exp Clin Cancer Res. 2019 Aug 16 ;38(1):360. Epub 2019 Aug 16. PMID:
31419989
Article Published Date
: Aug 15, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Mesothelioma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Curcumol attenuates epithelial-mesenchymal transition of nasopharyngeal carcinoma cells via TGF-β1.
May 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2018 Jun ;17(6):7513-7520. Epub 2018 Mar 28. PMID:
29620189
Article Published Date
: May 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumol
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
deguelin suppresses tumor-associated lymphangiogenesis and lymphatic metastasis.
Nov 14, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2010 Nov 15 ;127(10):2455-66. PMID:
20162567
Article Published Date
: Nov 14, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Deguelin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Demethoxycucumin protects MDA-MB-231 cells induced bone destruction through JNK and ERK pathways inhibition.
Jan 04, 2021
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2021 Jan 5. Epub 2021 Jan 5. PMID:
33403398
Article Published Date
: Jan 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Demethoxycurcumin
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
[+]
Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.
Jul 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jul 5 ;758:188-96. Epub 2015 Apr 8. PMID:
25863259
Article Published Date
: Jul 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2015 ;6(12):9854-76. PMID:
25918249
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Breast Cancer
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Anticarcinogenic Agents
Additional Keywords
:
Cancer Stem Cells
,
Epigenetic Modification In Cancer
[+]
Dietary delphinidin inhibits human colorectal cancer metastasis associating with upregulation of miR-204-3p and suppression of the integrin/FAK axis
Dec 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Dec 12 ;9(1):18954. Epub 2019 Dec 12. PMID:
31831830
Article Published Date
: Dec 11, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Delphinidin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
MicroRNA modulator
[+]
Dietary fish oil inhibits metastasizing human breast cancer cells.
Jan 01, 1994
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1994;22(2):131-41. PMID:
14502842
Article Published Date
: Jan 01, 1994
Study Type
: Animal Study
Additional Links
Substances
:
Fish Oil
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Exp Metastasis. 2009;26(5):415-24. Epub 2009 Mar 8. PMID:
19267249
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Stearic Acid (stearate)
Diseases
:
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
[+]
Diets containing EPA and DHA have an inhibitory effect on breast cancer growth and metastasis.
Apr 19, 1995
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 1995 Apr 19;87(8):587-92. PMID:
7752256
Article Published Date
: Apr 19, 1995
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
EPA (Eicosapentaenoic Acid)
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
[+]
DIM inhibits lung metastasis of mammary cancer cells in mice.
Oct 28, 2009
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2009 Oct 28. PMID:
19864400
Article Published Date
: Oct 28, 2009
Study Type
: Animal Study
Additional Links
Substances
:
DIM (3,3'-diindolylmethane)
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
Pharmacological Actions
:
Anti-metastatic
[+]
DIM is a potent chemopreventive compound for preventing metastatic behaviours of breast cancer cells induced by endocrine disrupting chemicals.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2017 Nov ;109(Pt 1):284-295. Epub 2017 Aug 24. PMID:
28844962
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
Problem Substances
:
Bisphenol A
,
Triclosan
[+]
DIM significantly reduced the proliferation and migration of nasopharyngeal carcinoma cells.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2016 Feb ;35(2):955-61. Epub 2015 Nov 16. PMID:
26574660
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
ECG may be used as an anti-invasion agent for the adjuvant treatment and metastasis control of human lung cancer cells.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2016 Aug ;94:1-10. Epub 2016 May 17. PMID:
27224248
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Fibronectin
[+]
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Fitoterapia. 2014 Jun ;95:83-92. Epub 2014 Mar 2. PMID:
24594241
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bergamot orange
,
Flavonoids
Diseases
:
Cancer Metastasis
,
Neuroblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Effects of Tussilago farfara polysaccharides on the expression of PD-1 (CD279) and PD-L1 (CD274) in peripheral blood and tumor tissue lymphocytes in with Lewis lung carcinoma.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Bull Exp Biol Med. 2020 Jul ;169(3):378-382. Epub 2020 Aug 4. PMID:
32749562
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Daisy
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Polysaccharides
[+]
Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2013 Sep ;33(9):3603-9. PMID:
24023285
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
,
Curcumin: Lipidated
Diseases
:
Pancreatic Cancer
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
[+]
EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Jun ;33(6):2972-80. Epub 2015 Mar 31. PMID:
25845434
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Carcinoma: Small Cell Lung
,
Nicotine/Tobacco Toxicity
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
EGCG inhibited SW780 bladder cancer tumor growth by down-regulation of NF-κB and MMP-9.
Dec 19, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Dec 20 ;41:56-64. Epub 2016 Dec 20. PMID:
28040581
Article Published Date
: Dec 19, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Emodin exerts anti-metastatic activity in pancreatic cancer both in vitro and in vivo.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID:
22375400
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Emodin suppresses angiogenesis and metastasis in anaplastic thyroid cancer.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Dec ;18(6):5191-5197. Epub 2018 Sep 26. PMID:
30272291
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
[+]
Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID:
26919952
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo.
Jul 18, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Jul 19 ;7(1):5806. Epub 2017 Jul 19. PMID:
28724926
Article Published Date
: Jul 18, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Berbamine
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Fermented milk administration to mice decreased or suppressed tumor growth, with less tumor vascularity, extravasation of tumor cells, and lung metastasis.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Immunother. 2015 Jun ;38(5):185-96. PMID:
25962107
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus casei
,
Milk: Fermented
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Immunomodulatory
[+]
Fisetin could effectively suppress proliferation and metastasis of triple negative breast cancer.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:772. Epub 2018 Jul 31. PMID:
30108501
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Forskolin has antimetastatic potential.
Dec 15, 1983
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 1983 Dec 15;32(6):801-4. PMID:
6686215
Article Published Date
: Dec 15, 1983
Study Type
: Animal Study
Additional Links
Substances
:
Coleus Forskohlii
Diseases
:
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
[+]
Fucoidan from Laminaria japonica exerts antitumor effects on angiogenesis and micrometastasis in triple-negative breast cancer cells.
Jan 27, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2020 Jan 28 ;149:600-608. Epub 2020 Jan 28. PMID:
32004612
Article Published Date
: Jan 27, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
NF-kappaB Inhibitor
[+]
Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis in breast cancer.
Mar 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2013 Apr ;34(4):874-84. Epub 2012 Dec 28. PMID:
23275155
Article Published Date
: Mar 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Breast Cancer
,
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Fucoidan inhibits the in vitro and in vivo invasion of hepatocellular carcinoma cells.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Oct ;83:607-616. Epub 2016 Jul 25. PMID:
27459117
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Fucoidan suppresses hypoxia-induced lymphangiogenesis and lymphatic metastasis in mouse hepatocarcinoma.
Jun 02, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2015 Jun 3 ;13(6):3514-30. Epub 2015 Jun 3. PMID:
26047481
Article Published Date
: Jun 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Hypoxia
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Galangin inhibits epithelial-mesenchymal transition and angiogenesis by downregulating CD44 in glioma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cancer. 2019 ;10(19):4499-4508. Epub 2019 Jul 25. PMID:
31528214
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Glioma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Galangin inhibits tumor growth and metastasis of B16F10 melanoma.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2013 Jan ;114(1):152-61. PMID:
22887049
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Ganoderma lucidum inhibits tumorigenesis and metastasis of human hepatoma cells in cells and animal models.
Jun 10, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Jun 10 ;57(11):5049-57. PMID:
19422227
Article Published Date
: Jun 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
Additional Keywords
:
Plant Extracts
[+]
Genistein inhibits metastasis of human prostate cancer in mice.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ann Thorac Surg. 2010 Mar;89(3):781-786. PMID:
18339885
Article Published Date
: Mar 01, 2010
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Cancer Metastasis
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Genistein reinforces the inhibitory effect of Cisplatin on liver cancer recurrence and metastasis after curative hepatectomy.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2013 ;14(2):759-64. PMID:
23621233
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Liver Cancer
,
Liver Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
[+]
Germanium prevents pulmonary metastasis of Lewis lung cancer.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Appl Physiol. 2008 May;103(1):33-40. Epub 2008 Jan 11. PMID:
3373232
Article Published Date
: May 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Germanium
Diseases
:
Breast Cancer: Metastatic
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Ginkgo biloba exocarp extracts played the effects of anti-tumor and anti-metastatic depending upon the inhibition of tumor angiogenesis.
Nov 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Nov 4 ;192:406-412. Epub 2016 Aug 17. PMID:
27649680
Article Published Date
: Nov 03, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Dose Response
[+]
Ginkgo biloba extract inhibits metastasis and in gastric cancer.
Sep 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2019 Sep 11 ;25:6836-6845. Epub 2019 Sep 11. PMID:
31509521
Article Published Date
: Sep 10, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Ginkgolic acid reduced the expression of the key enzymes involved in lipogenesis and restrained the tumor growth.
Mar 25, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2015 Mar 26. Epub 2015 Mar 26. PMID:
25895130
Article Published Date
: Mar 25, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Pancreatic Cancer
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
[+]
Ginsenoside 20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.
Aug 29, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Biochem Biophys. 2020 Aug 30:108569. Epub 2020 Aug 30. PMID:
32877662
Article Published Date
: Aug 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
[+]
Ginsenoside Rd treatment attenuates breast cancer metastasis.
Sep 18, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Sep 19 ;6:33709. Epub 2016 Aug 19. PMID:
27641158
Article Published Date
: Sep 18, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Panax Notoginseng
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
MicroRNA modulator
Additional Keywords
:
Dose Response
[+]
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition and invasion of lung cancer by down-regulating FUT4.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jan 12 ;7(2):1619-32. PMID:
26636541
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
E-cadherin down-regulation
[+]
Ginsenoside Rg3 inhibits migration and invasion, and promotes apoptosis of Caco-2 cells.
Jan 07, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2019 Jan 8 ;106:131-138. Epub 2019 Jan 8. PMID:
30633886
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 might be a useful agent for the treatment of metastatic thyroid cancers.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):849-857. Epub 2018 Aug 23. PMID:
30136914
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rh1 inhibits colorectal cancer cell migration and invasion in vitro and tumor growth in vivo.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2019 Oct ;18(4):4160-4166. Epub 2019 Aug 14. PMID:
31579419
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Gold nanoparticles carrying quercetin inhibited EMT, angiogenesis and metastasis of the breast cancer cells.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Cell Prolif. 2016 Dec ;49(6):678-697. Epub 2016 Aug 18. PMID:
27641938
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gold (nanoparticles)
,
Quercetin
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
[+]
Gomisin A has the potential to reduce metastatic melanoma through its anti-proliferative and anti-metastatic effects.
Dec 06, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytomedicine. 2019 Dec 7 ;68:153147. Epub 2019 Dec 7. PMID:
32028184
Article Published Date
: Dec 06, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Schisandra
Diseases
:
Melanoma: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Green tea has a growth inhibitory and antimetastatic effect on metastasis-specific mouse mammary cancer.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2005 Mar 1;11(5):1918-27. PMID:
15756018
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Breast Cancer: Lung Metastasis
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Hesperidin exhibits in vitro and in vivo antitumor effects in human osteosarcoma MG-63 cells and xenograft mice models.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Nov ;16(5):6299-6306. Epub 2018 Sep 14. PMID:
30405765
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 ;7(7):5065-87. Epub 2015 Jun 24. PMID:
26115086
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Prostate Cancer
,
Prostate Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
High doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Sep 1 ;232:116657. Epub 2019 Jul 13. PMID:
31306660
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Cancer Metastasis
,
Glioblastoma
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2019 ;12:7405-7413. Epub 2019 Sep 10. PMID:
31571901
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
[+]
Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.
Jan 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2017 10 5 ;8(10):e3089. Epub 2017 Oct 5. PMID:
28981104
Article Published Date
: Jan 04, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Phellinus Linteus
,
Polyphenols
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
[+]
Holy basil has anti-melanoma and radioprotective properties.
Apr 01, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Apr;49(4):428-36. PMID:
21428866
Article Published Date
: Apr 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Melanoma
,
Radiation Induced Illness
Pharmacological Actions
:
Anti-metastatic
,
Radioprotective
[+]
Honokiol could provide novel chemopreventive or therapeutic options for preventing both lung tumor progression and lung cancer metastasis.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2017 Feb ;10(2):133-141. Epub 2016 Nov 14. PMID:
27849557
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Cancer Metastasis
,
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
STAT3 Inhibitor
[+]
Honokiol has potential for treating neuroblastomas.
Oct 11, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2015 Oct 12. Epub 2015 Oct 12. PMID:
26454217
Article Published Date
: Oct 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Autophagy Up-regulation
[+]
Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells.
Mar 22, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Mar 23. Epub 2016 Mar 23. PMID:
27027343
Article Published Date
: Mar 22, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Breast Cancer: estrogen receptor alpha-positive
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Autophagy Up-regulation
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
,
Synergy with Tamoxifen
[+]
Huaier restrains proliferative and migratory potential of hepatocellular carcinoma cells.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cancer. 2017 ;8(19):4087-4097. Epub 2017 Nov 6. PMID:
29187885
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Hyperbaric oxygen therapy significantly reduced the number and area of metastatic lesions in the triple negative model.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(8):e0183254. Epub 2017 Aug 23. PMID:
28832662
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
In mice given essential oil extracted from P. tortuosus, tumor weight was inhibited by 98% compared to that in mice that did not receive the oil.
Oct 07, 2015
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2015 Oct 8. Epub 2015 Oct 8. PMID:
26477879
Article Published Date
: Oct 07, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Essential Oils: Unspecified
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
In vivo experiments showed that Huaier significantly suppressed the tumor volume of SiHa cell xenografts.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2015 Sep ;47(3):1054-60. Epub 2015 Jul 20. PMID:
26201539
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Indicaxanthin from prickly pear cactus impairs melanoma cell proliferation, invasiveness, and tumor progression.
Nov 14, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytomedicine. 2018 Nov 15 ;50:19-24. Epub 2018 Sep 18. PMID:
30466978
Article Published Date
: Nov 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Prickly Pear Cactus
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3465-3477. PMID:
31432702
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ligustrazine
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Chemothapeutic Synergy: Paclitaxel
[+]
Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Sci Rep. 2016 ;6:21731. Epub 2016 Feb 25. PMID:
26911838
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
STAT3 Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Isoliquiritigenin may be an effective therapeutic agent against ovarian cancer.
Oct 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Oct 16 ;24(20). Epub 2019 Oct 16. PMID:
31623144
Article Published Date
: Oct 15, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Aug 04, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID:
31004603
Article Published Date
: Aug 04, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
Wnt/β-catenin signaling pathway modulation
[+]
JWH-015 treatment significantly reduced primary tumor burden and metastasis of luciferase-tagged murine mammary carcinoma 4T1 cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Breast Cancer (Dove Med Press). 2016 ;8:59-71. Epub 2016 Apr 15. PMID:
27186076
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids: Synthetic
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
JWH-015 treatment significantly reduced primary tumor burden and metastasis of luciferase-tagged murine mammary carcinoma 4T1 cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Breast Cancer (Dove Med Press). 2016 ;8:59-71. Epub 2016 Apr 15. PMID:
27186076
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids: Synthetic
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Kaempferol can safely inhibit the metastasis of the 786-O RCC cells into the lungs by about 87.4%.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Med Sci. 2017 ;14(10):984-993. Epub 2017 Aug 18. PMID:
28924370
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kaempferol
Diseases
:
Kidney Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
treatment outcome
[+]
Kaempferol might act as a therapeutic potential candidate for cancer metastasis.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 2015 Feb ;93(1):16-27. Epub 2014 Sep 12. PMID:
25453494
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kaempferol
Diseases
:
Breast Cancer: Triple Negative
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Korean Red Ginseng extracts might have the ability to reduce the incidence of leukemia.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Oct ;40(4):431-436. Epub 2016 Aug 4. PMID:
27746697
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Lymphoma
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Krill oil perturbs proliferation and migration of mouse colon cancer cells.
Sep 14, 2020
Click here to read the entire abstract
Pubmed Data
: Lipids. 2020 Sep 15. Epub 2020 Sep 15. PMID:
32931040
Article Published Date
: Sep 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.
May 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2013 Jun ;6(6):603-13. Epub 2013 Apr 26. PMID:
23625311
Article Published Date
: May 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Licorice
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Liposomal honokiol is a potential therapeutic agent to block liver cancer metastasis without severe side effects.
Jan 02, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Jan 3 ;8(1):915-932. PMID:
27906672
Article Published Date
: Jan 02, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Honokiol
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Liquiritigenin potentiates the inhibitory effects of cisplatin on invasion and metastasis in B16F10 melanoma cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(5):761-70. Epub 2015 May 15. PMID:
25978595
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Liquiritigenin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Luteolin can be a chemotherapeutic agent against colorectal cancer.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2014 Nov ;33(11):1176-85. Epub 2014 Feb 14. PMID:
24532706
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Luteolin effectively suppressed metastases of breast cancer by reversing epithelial-mesenchymal transition.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb ;37(2):895-902. Epub 2016 Dec 12. PMID:
27959422
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Dose Response
[+]
Luteolin inhibits invasion of prostate cancer cells.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Mol Cancer Ther. 2009 Jun;8(6):1684-91. Epub 2009 Jun 9. PMID:
19509250
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Cancer Metastasis
,
Lung Cancer
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells.
Jan 20, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jan 21. Epub 2019 Jan 21. PMID:
30663726
Article Published Date
: Jan 20, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Luteolin may serve as an effective anti-tumor drug in gastric cancer treatment.
Feb 26, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Transl Med. 2017 Feb 27 ;15(1):52. Epub 2017 Feb 27. PMID:
28241766
Article Published Date
: Feb 26, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Dose Response
[+]
Lycopene inhibits experimental metastasis of human hepatoma in athymic mice.
Mar 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Mar ;138(3):538-43. PMID:
18287363
Article Published Date
: Mar 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
Diseases
:
Cancer Metastasis
,
Liver Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Magnolol is a potential candidate for glioma treatment.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Neuropathol Exp Neurol. 2018 Jun 1 ;77(6):426-436. PMID:
29788114
Article Published Date
: May 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Magnolol
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
[+]
Maitake D-Fraction Pro4X prevents breast carcinogenesis, blocks tumor invasiveness, reduces angiogenesis, and increases overall survival.
Jul 10, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Med. 2016 Jul 11. Epub 2016 Jul 11. PMID:
27401257
Article Published Date
: Jul 10, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Maitake Mushroom
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Melatonin has shown to be effective in controlling metastatic breast cancer in vitro and in vivo.
Aug 20, 2015
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2015 Aug 21. Epub 2015 Aug 21. PMID:
26292662
Article Published Date
: Aug 20, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
[+]
Melatonin is promising in the management of prostate cancer metastasis.
Nov 28, 2020
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2020 Nov 29. Epub 2020 Nov 29. PMID:
33251599
Article Published Date
: Nov 28, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Cancer: Prostate
Pharmacological Actions
:
Anti-metastatic
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
[+]
Metformin in combination with curcumin inhibits the growth, metastasis and angiogenesis of hepatocellular carcinoma.
Aug 18, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2017 Aug 19. Epub 2017 Aug 19. PMID:
28833603
Article Published Date
: Aug 18, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis.
Jan 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2018 Jan 12 ;9(4):5169-5183. Epub 2017 Dec 26. PMID:
29435170
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
S-Adenosylmethionine (SAMe)
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Methylsulfonylmethane and tamoxifen synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.
Jun 18, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cancer. 2015 Jun 19 ;15:474. Epub 2015 Jun 19. PMID:
26084564
Article Published Date
: Jun 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Synergy with Tamoxifen
[+]
Modulation of antioxidant potential with coenzyme Q10 suppressed invasion of temozolomide-resistant glioma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:3061607. Epub 2019 Mar 12. PMID:
30984333
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Chemotherapeutic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Monacolin K, a metabolite of red yeast rice, reduces tumor progression and metastasis of Lewis lung cancer.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8258-65. PMID:
19754167
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Red Yeast Rice
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Myricetin effectively represses the malignant progression of prostate cancer.
Jul 24, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 Jul 25 ;48(3):1230-1244. Epub 2018 Jul 25. PMID:
30045021
Article Published Date
: Jul 24, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Myricetin
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Selective Cytotoxicity
[+]
N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling.
Jan 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Exp Clin Cancer Res. 2019 Jan 3 ;38(1):2. Epub 2019 Jan 3. PMID:
30606241
Article Published Date
: Jan 02, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Antiproliferative
,
Apoptotic
[+]
Nano curcumin may be an effective therapeutic modality for cervical cancer.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:20051. Epub 2016 Feb 3. PMID:
26837852
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
Additional Keywords
:
E6 Oncoprotein
Problem Substances
:
Benzo(a)pyrene
[+]
Nanoparticle conjugation of ginsenoside Rg3 inhibits hepatocellular carcinoma development and metastasis.
Dec 08, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Small. 2019 Dec 9:e1905233. Epub 2019 Dec 9. PMID:
31814271
Article Published Date
: Dec 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
[+]
Nobiletin may have potential use as a chemopreventive agent against nasopharyngeal cancer metastasis.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Expert Opin Ther Targets. 2015 Mar ;19(3):307-20. Epub 2015 Jan 7. PMID:
25563790
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Nobiletin might have a great potential for treating glioblastoma.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 May ;37(5):2847-2856. Epub 2017 Mar 23. PMID:
28339056
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Nocturnal melatonin directly inhibited tumour growth and invasion of human Leiomyosarcoma via suppression of the Warburg effect.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2016 Mar ;60(2):167-77. Epub 2015 Dec 23. PMID:
26607298
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Leiomyosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Cancer Glycolysis
[+]
Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis.
Dec 26, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Dec 27 ;7(52):86225-86238. PMID:
27863391
Article Published Date
: Dec 26, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Nordihydroguaiaretic acid (NDGA)
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Novel medicinal mushroom blend as a promising supplement in integrative oncology.
May 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 May 14 ;21(10). Epub 2020 May 14. PMID:
32423132
Article Published Date
: May 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Agaricus Blazei
,
Maitake Mushroom
,
Reishi Mushroom
,
Shiitake Mushroom
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Chemotherapeutic
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
[+]
Oleocanthal combined with lapatinib treatment synergized against HER-2 positive breast cancer.
Feb 14, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Feb 15 ;11(2). Epub 2019 Feb 15. PMID:
30781364
Article Published Date
: Feb 14, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Oleocanthal
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Oral administration of dandelion root extract inhibited the growth of human colon xenograft models by more than 90%.
Aug 21, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Aug 22. Epub 2016 Aug 22. PMID:
27564258
Article Published Date
: Aug 21, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dandelion
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
,
Plant Extracts
,
Selective Cytotoxicity
[+]
Oral tangeretin treatment effectively reduced the tumor cell proliferation markers and suppressed metastasis.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2014 Nov ;25(11):1140-53. Epub 2014 Aug 1. PMID:
25151216
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Tangeretin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
,
Cyclooxygenase 2 Inhibitors
,
Nitric Oxide Inhibitor
[+]
Orally administered bovine lactoferrin systemically inhibits VEGF (165)-mediated angiogenesis.
Jan 14, 2001
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2001 Jan 15 ;91(2):236-40. PMID:
11146451
Article Published Date
: Jan 14, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Cancers: All
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Angiogenic
,
Anti-metastatic
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell Int. 2016 ;16:57. Epub 2016 Jul 22. PMID:
27453691
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Oridonin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Wnt/β-catenin signaling pathway modulation
[+]
Oridonin inhibits VEGF-A-associated angiogenesis and epithelial-mesenchymal transition of breast cancer.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Aug ;16(2):2289-2298. Epub 2018 Jun 11. PMID:
30008931
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Oridonin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Paeoniflorin inhibits glioblastoma growth in vivo and in vitro.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Manag Res. 2018 ;10:887-897. Epub 2018 Apr 27. PMID:
29740218
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Paeoniflorin inhibits macrophage-mediated lung cancer metastasis.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2015 Dec ;13(12):925-32. PMID:
26721711
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Paeoniflorin inhibits migration and invasion of human glioblastoma cells.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurochem Res. 2018 Mar ;43(3):760-774. Epub 2018 Feb 8. PMID:
29423667
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Cancer Metastasis
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Paeonol impeded cell viability, migration and invasion and triggered apoptosis by regulating miR-21-5p/KLF6 axis in HCC cells.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Manag Res. 2020 ;12:5931-5943. Epub 2020 Jul 17. PMID:
32765094
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeonol
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
[+]
Paeonol inhibits B16F10 melanoma metastasis in vitro and in vivo.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: IUBMB Life. 2015 Oct ;67(10):778-88. Epub 2015 Oct 10. PMID:
26452780
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeonol
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
NF-kappaB Inhibitor
,
STAT3 Inhibitor
[+]
pantethine represents a novel potential, well-tolerated, therapeutic tool in patients with ovarian cancer.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2016 ;6:244. Epub 2016 Nov 16. PMID:
27900284
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pantethine
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells.
Oct 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2013 Oct 31 ;4:e891. Epub 2013 Oct 31. PMID:
24176849
Article Published Date
: Oct 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Parthenolide
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Peach polyphenols inhibited tumor growth and reduced the risk of metastasis in MDA-MB-435 cells at levels achievable with diet.
Mar 18, 2014
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2014 Mar 19. Epub 2014 Mar 19. PMID:
24745759
Article Published Date
: Mar 18, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Peach
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Anti-Tumor
,
Chemopreventive
,
Matrix Metalloproteinases Inhibitors
Additional Keywords
:
Breast Cancer Diet
,
Fruit Extract
,
Gene Expression Regulation
[+]
Pectic acid, a natural component of apple, can prevent metastasis in breast cancer cell lines.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Dec ;84:637-644. Epub 2016 Sep 30. PMID:
27697635
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apple Pectin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Physical activity delays accumulation of immunosuppressive myeloid-derived suppressor cells
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2020 ;15(6):e0234548. Epub 2020 Jun 15. PMID:
32542046
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Lung Cancer
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Immunomodulatory
[+]
Piceatannol may be a useful anticancer natural product.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2012 ;2012:672416. Epub 2012 Feb 8. PMID:
22496613
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Piceatannol
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Pineapple bromelain has anti-tumor properties superior to the chemo-agent 5-fluorouracil.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID:
17893836
Article Published Date
: Oct 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
,
Pineapple
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Drug: 5-flourouracil
,
Food as Medicine
,
Hall of Fame
,
Superiority of Natural Substances versus Drugs
[+]
Piperlongumine a promising potential candidate for use as a therapeutic option for patients with PHEO/PGL and SDHB mutations.
May 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 26. Epub 2016 May 26. PMID:
27244895
Article Published Date
: May 25, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Piperlongumine
Diseases
:
Cancers: All
,
Liver Cancer
,
Neuroblastoma
,
Pheochromocytoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Selective Cytotoxicity
[+]
Piperlongumine is a promising antitumor agent that deserves further study for colorectal cancer treatment.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2020 ;13:5591-5603. Epub 2020 Jun 15. PMID:
32606774
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cyclin D1 Down-Regulation
[+]
Piperlongumine was a direct STAT3 inhibitor and caused regression of breast cancer cell line xenografts in nude mice.
Mar 30, 2014
Click here to read the entire abstract
Pubmed Data
: Oncogene. 2014 Mar 31 ;0. Epub 2014 Mar 31. PMID:
24681959
Article Published Date
: Mar 30, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Long Pepper
,
Piperlongumine
Diseases
:
Breast Cancer
,
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Anti-Tumor
,
Apoptotic
,
STAT3 Inhibitor
Additional Keywords
:
Disease Regression
,
Epigenetic Modification In Cancer
[+]
Polyphenol enrichment of a blueberry preparation by fermentation increases its chemopreventive potential.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Transl Med. 2016 ;14(1):13. Epub 2016 Jan 14. PMID:
26762586
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Blueberry
,
Fermented Foods and Beverages
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
[+]
Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2000 ;12(1-4):83-8. PMID:
11216510
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Cancer Metastasis
,
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Protein regulator of cytokinesis 1 is a novel downstream target of piperlongumine in gastric cancer.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2017 Jul ;21(7):1329-1341. Epub 2017 Feb 12. PMID:
28190297
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Piperlongumine
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Pterostilbene exerts anticancer activity on non-small-cell lung cancer.
Aug 13, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Aug 14 ;7(1):8091. Epub 2017 Aug 14. PMID:
28808300
Article Published Date
: Aug 13, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Pterostilbene inhibited the migratory and invasive potential of triple-negative MDA-MB-231 and Hs578t cells.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Jun ;26(6):675-85. Epub 2015 Mar 6. PMID:
25792283
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
[+]
Puerarin suppressed the invasion and migration of NSCLC macrophages, restrained the expression of angiogenesis factors.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2017 Feb ;50(2):545-554. Epub 2017 Jan 5. PMID:
28101568
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Puerarin
Diseases
:
Cancer Metastasis
,
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Quercetin suppresses the metastatic ability of lung cancer.
Jan 09, 2017
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 2017 10 ;1864(10):1746-1758. Epub 2017 Jun 23. PMID:
28648644
Article Published Date
: Jan 09, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Cancer Metastasis
,
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
[+]
Resveratrol prevents inflammation-dependent hepatic melanoma metastasis.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Transl Med. 2011 ;9:59. Epub 2011 May 12. PMID:
21569399
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Inflammation
,
Liver Cancer
,
Liver Cancer: Metastatic
,
Melanoma: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Interleukin-18 down-regulation
,
Vascular Cell Adhesion Molecule-1 Inhibitor
[+]
Resveratrol-loaded nanocapsules inhibit murine melanoma tumor growth.
Apr 01, 2016
Click here to read the entire abstract
Pubmed Data
: Colloids Surf B Biointerfaces. 2016 Apr 2 ;144:65-72. Epub 2016 Apr 2. PMID:
27070053
Article Published Date
: Apr 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Rosemary extract causes ROS-induced necrotic cell death and inhibits tumor growth in vivo.
Jan 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Jan 28 ;9(1):808. Epub 2019 Jan 28. PMID:
30692565
Article Published Date
: Jan 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Rosemary
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Sea cucumber extract TBL-12 could suppress the proliferation and metastasis of human prostate cancer cells.
Mar 18, 2019
Click here to read the entire abstract
Pubmed Data
: Prostate. 2019 Mar 19. Epub 2019 Mar 19. PMID:
30889629
Article Published Date
: Mar 18, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sea Cucumber
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sesamin can potentially be employed as an effective adjuvant therapeutic agent in ameliorating tumor development and progression.
Nov 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Nov 15 ;815:512-521. Epub 2017 Oct 12. PMID:
29032105
Article Published Date
: Nov 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sesamin
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Shikonin has been shown to strongly stimulate the induction of tumor immunogenicity.
May 26, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 27. Epub 2016 May 27. PMID:
27248319
Article Published Date
: May 26, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Shikonin
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Cytotoxic
,
Immunomodulatory
[+]
Shikonin inhibited the viability, migration and invasion of SW480 cells.
Feb 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Feb 15 ;797:1-8. Epub 2017 Jan 12. PMID:
28088387
Article Published Date
: Feb 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Shikonin
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
[+]
Shikonin reduced the activation and expression of STAT3, FAK and Src in vivo and reduced tumorigenicity, growth and metastasis of 4T1 cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2015 ;5:10194. Epub 2015 May 14. PMID:
25973915
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Lithospermum erythrorhizon
,
Shikonin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
STAT3 Inhibitor
Additional Keywords
:
Cancer Stem Cells
[+]
Silymarin suppresses HepG2 hepatocarcinoma cell progression.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2020 Feb ;72(1):199-207. Epub 2020 Jan 8. PMID:
32016841
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
Spirulina extract enriched for Braun-type lipoprotein (Immulina®) for inhibition of 4T1 breast tumors' growth and metastasis.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Feb ;34(2):368-378. Epub 2019 Nov 5. PMID:
31691383
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Spirulina
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Suforaphane, a compound found within broccoli, inhibits lung metastasis induced by melanoma cells in tumor-bearing animals.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Breast Cancer Res Treat. 2006 Oct;99(3):333-40. Epub 2006 May 9. PMID:
16600309
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Lung Cancer
,
Melanoma
,
Melanoma: Metastatic
Pharmacological Actions
:
Anti-metastatic
[+]
Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2008 Nov 1;14(21):6855-66. PMID:
18980980
Article Published Date
: Nov 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Sulforaphane increases cell-mediated immune response in melanoma-induced metastatic tumor-bearing mice.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Clin Invest. 2010 Apr 1;120(4):1043-55. Epub 2010 Mar 24. PMID:
17849266
Article Published Date
: Apr 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,