Anti-metastatic

Name	AC	CK
Curcumin	109	142
Ginsenosides	84	128
Flavonoids	67	87
Thymoquinone	45	54
Resveratrol	44	53
Berberine	45	49
Fucoidan	22	47
Anthocyanins	14	45
EGCG (Epigallocatechin gallate)	28	43
Quercetin	30	39
Luteolin	27	37
Vitamin C	18	37
Melatonin	28	35
Polyphenols	29	35
Honokiol	28	33
Shikonin	25	33
Apigenin	21	32
Sulforaphane	24	31
Magnolol	12	26
Baicalein	23	25
Cordyceps Militaris	15	24
Reishi Mushroom	17	24
Tanshinone IIA	20	23
Cannabidiol	17	22
Gallic Acid	16	22
Betulinic acid	14	20
Cannabis	13	20
Huaier (Trametes robiniophila murr)	16	20
Kaempferol	14	20
Paeoniflorin	16	20
Pterostilbene	13	20
Cucurbitacin B	16	19
Ginkgo biloba	14	19
Myricetin	12	19
Salvia miltiorrhiza	18	19
Cannabinoids	16	18
Emodin	15	18
Nobiletin	16	18
Piperlongumine	14	18
Blueberry	10	17
Gingerol	13	17
Licorice	16	17
Lycopene	6	17
Oridonin	11	17
Beta-Elemene	14	16
Ellagic Acid	11	16
Lactoferrin	12	16
Mangiferin	12	16
Zerumbone	11	16
Astragaloside	13	15
Delta-tetrahydrocannabinol (THC)	9	15
Fucoxanthin	7	15
Garlic	10	15
Genistein	13	15
Piperine	10	15
Selenium	6	15
Silibinin	14	15
Ursolic Acid	14	15
Andrographis	10	14
Bee Venom	13	14
Bromelain	4	14
Crocin	10	14
Green Tea	10	14
Isoliquiritigenin	11	14
Naringenin	14	14
Pineapple	3	14
Arctigenin	12	13
Celastrol	12	13
Fisetin	11	13
Pomegranate	11	13
Bisdemethoxycurcumin	8	12
Wogonin	11	12
Asiatic Acid	8	11
Astaxanthin	9	11
Benzyl isothiocyanate	9	11
Curcumol	10	11
Organosulfur Compounds	10	11
Paeonol	9	11
Parthenolide	6	11
Poria cocos	9	11
Vitamin D	11	11
Xanthohumol	8	11
Cannabinoids: Synthetic	6	10
Cinnamaldehyde	7	10
Deguelin	9	10
Ginger	10	10
Hesperidin	8	10
Peony	8	10
Phellinus Linteus	8	10
Piceatannol	7	10
Tangeretin	7	10
Turmeric	9	10
Whey	1	10
Ashwagandha	9	9
Caffeic acid phenethyl ester	7	9
Chrysin	9	9
Ginseng	4	9
Isothiocyanates	8	9
Oleuropein	9	9
Phloretin	5	9
Prunella vulgaris	7	9
Puerarin	8	9
Verbascoside	8	9
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	3	8
Apple Polyphenols	4	8
Berbamine	7	8
Cucurbitacin E	6	8
Diosgenin	7	8
Echinacea	6	8
Elecampane	8	8
Ginseng (Korean)	7	8
Lotus	8	8
Neem	7	8
Panax Notoginseng	7	8
Phenethyl isothiocyanate	8	8
Sinomenine	7	8
Spirulina	5	8
Stilbenes	4	8
Theanine	5	8
6-Shogaol	6	7
Allicin	6	7
Aloe Vera	6	7
Andrographolide	7	7
Biochanin A	6	7
Bufalin	7	7
Catechin	6	7
Dandelion	6	7
Formononetin	7	7
Grape	7	7
Holy Basil	5	7
Icariin	4	7
Isoflavones	4	7
Lignans	5	7
Moringa oleifera	7	7
Nigella sativa (aka Black Seed)	6	7
Orange: Mandarin	3	7
Seaweed: Brown	6	7
Artemisinin	5	6
Crocetin	5	6
Demethoxycurcumin	5	6
Eugenol	6	6
Ferulic acid	4	6
Frankincense	5	6
Mangosteen	5	6
Mistletoe	4	6
Mulberry	5	6
Punicalagin	6	6
Rosemaric Acid	6	6
Saffron	5	6
Sesamin	5	6
Vanillin	4	6
Vitamin E	5	6
Alpha-Lipoic Acid	5	5
Apple Pectin	2	5
Bee Propolis	4	5
Bergamot	5	5
Beta Sitosterol	3	5
Bitter Melon	4	5
Black Raspberry	1	5
Black Tea	5	5
Carbon 60	3	5
Carrot	4	5
Citrus naringin	5	5
Delphinidin	4	5
Feverfew	1	5
Guduchi	4	5
Lactobacillus casei	2	5
Ligustrazine	4	5
Maitake Mushroom	3	5
Medicinal Mushrooms	4	5
Oleanolic acid	5	5
Olive leaf extract	3	5
Phlorotannins	5	5
Rhubarb	5	5
Rosmarinic acid	5	5
Safflower	5	5
Sea Cucumber	3	5
Burdock	4	4
Chaga Mushroom (Inonotus obliquus)	4	4
Chlorogenic Acid	3	4
Citrus Triterpenoids	2	4
DHA (Docosahexaenoic Acid)	3	4
False Black Pepper	4	4
Fenugreek	3	4
Gold (nanoparticles)	3	4
Grapefruit	4	4
Harmine	4	4
Kiwifruit	4	4
Krill	3	4
Liquiritigenin	3	4
Lysine	2	4
MSM (Methylsulfonylmethane)	3	4
Proline	2	4
Rose	4	4
S-Adenosylmethionine (SAMe)	3	4
Schisandra	3	4
St. Johns Wort	4	4
Tomato	3	4
Urolithin A	4	4
Walnut	4	4
Wormwood	4	4
Acorus calamus	2	3
Agaricus Blazei	2	3
Amygdalin	3	3
Antineoplaston A5	1	3
Antineoplastons	1	3
Artesunate	3	3
Astragalus	2	3
Bacopa	3	3
Basil	2	3
Bergamot orange	2	3
Black Pepper	2	3
Capsaicin	3	3
Cardamonin	3	3
Citrus Peel	3	3
Coffee	3	3
Cordyceps sinensis	3	3
Daisy	2	3
Fig	2	3
Fish Oil	2	3
Folate	2	3
Germanium	2	3
Goji	3	3
Grape Seed Extract	3	3
Hibiscus sabdariffa	2	3
Homeopathic Medicine: All	2	3
Hops	3	3
Hydroxytyrosol	3	3
Isothiocyanate	3	3
Lactobacillus reuteri	1	3
Litchi	2	3
Lithospermum erythrorhizon	2	3
Lupeol	3	3
Manuka Honey	3	3
Mushrooms: All	2	3
NAC (N-acetyl-L-cysteine)	2	3
Noni	3	3
Oleocanthal	2	3
Onion	3	3
Patchouli	2	3
Peach	2	3
Perilla	3	3
Persimmon	3	3
Phyllanthus amarus	3	3
Phyllanthus niruri (Stonebreaker)	3	3
Phyllanthus urinaria	3	3
Pine Bark Extract	3	3
Plantago	3	3
Pomegranate Peel	3	3
Proanthocyanidins	3	3
Shiitake Mushroom	2	3
Strawberry	2	3
Sweet Potato	2	3
Tetrahydrocurcumin	3	3
Theaflavins	3	3
Thistle	3	3
Tocotrienol: Delta	3	3
Tomatidine	3	3
Trichosanthes Kirilowii	2	3
White Mulberry	3	3
Xanthones	3	3
Zataria multiflora	1	3
acetyl-11-keto-beta-boswellic acid	2	3
Adlay	2	2
Amla Fruit	1	2
Amygdalin (laetrile)	2	2
Antrodia camphorata	2	2
Apple	2	2
Asparagus	2	2
Baking Soda	1	2
Bamboo	1	2
Bifidobacterium Longum	1	2
Boswellia	1	2
Broccoli	1	2
Cabbage	1	2
Cafestol	2	2
Caffeic Acid	2	2
Carnosic Acid	2	2
Carnosine	2	2
Carnosol	1	2
Carvacrol	2	2
Chinese Skullcap	2	2
Cloudberry	1	2
Coenzyme Q10	1	2
Coleus Forskohlii	1	2
Collards	1	2
Coptis chinensis	2	2
Curcumin: Lipidated	1	2
Curcuminoids	2	2
DIM (3,3'-diindolylmethane)	1	2
EPA (Eicosapentaenoic Acid)	1	2
Endocannabinoids	2	2
Eriodictyol	2	2
Essential Oils: Unspecified	1	2
Fermented Foods and Beverages	1	2
Flaxseed	2	2
Gac	2	2
Galbanic Acid	2	2
Genipin	2	2
Gleditsia sinensis	1	2
Gynostemma	2	2
Honey	2	2
Horse Chestnut	2	2
Hyaluronic Acid	1	2
Hydrangea	2	2
Indole-3-Carbinol	2	2
Inulin	1	2
Jujube	1	2
Ketone Bodies	1	2
Long Pepper	1	2
Loquat Leaves	2	2
Marigold	2	2
Milk: Fermented	1	2
Nordihydroguaiaretic acid (NDGA)	1	2
Palash	1	2
Panax Ginseng	2	2
Panaxadiol	1	2
Pantethine	1	2
Prickly Pear Cactus	1	2
Probiotics	2	2
Psychedelics:All	2	2
Raspberry	2	2
Red Clover	2	2
Red Sage	2	2
Red Wine	1	2
Red Yeast Rice	1	2
Rice Bran	2	2
Rosemary	1	2
Saikosaponin	2	2
Satsuma	1	2
Seaweed	2	2
Sesamol	1	2
Silymarin	1	2
Sophora Flavescens	2	2
Soursop	2	2
Stearic Acid (stearate)	1	2
Syrian rue	2	2
Tannic Acid	2	2
Terminalia	2	2
Thymol	1	2
Tocotrienol: Gamma	1	2
Toona sinensis	2	2
Triptolide	1	2
Valerian	1	2
Velvet antler	1	2
Venom: Snake	2	2
Vinegar	1	2
Viruses: Beneficial	1	2
Vitamin A	2	2
Vitamin K	1	2
Vitamin K2	1	2
Vitexins	2	2
Yerba Mate	1	2
cottonseed oil (gossypol)	1	2
4-Shogaol	1	1
African Basil	1	1
Agrimony	1	1
Angelica	1	1
Artichoke	1	1
Babchi	1	1
Bai Zhu	1	1
Beans: All	1	1
Berberis amurensis	1	1
Beta-Caryophyllene	1	1
Beta-glucan	1	1
Betaine	1	1
Betel	1	1
Bitter Apple	1	1
Black Cherry	1	1
Black Currant	1	1
Cannabigerol	1	1
Carotenoids	1	1
Catechols	1	1
Chamomile	1	1
Chili pepper	1	1
Chlorella (Algae)	1	1
Chokeberry	1	1
Chrysanthemum Indicum	1	1
Cinnamon	1	1
Coptidis rhizoma	1	1
Coriandrum sativum	1	1
Corn Silk	1	1
Cruciferous Vegetables	1	1
Cucurbitacin D	1	1
Curcuma phaeocaulis	1	1
Curry Leaves	1	1
Cyanidin	1	1
Cyanidin 3-glucoside	1	1
D-Limonene	1	1
Dracaena draco	1	1
Eggplant	1	1
Elm tree	1	1
Epicatechin	1	1
Epimedium	1	1
Evening Primrose Oil	1	1
False Daisy	1	1
Fiber	1	1
Folic Acid	1	1
Fruit: All	1	1
Ganoderma colossum	1	1
Garcinia Mangostana	1	1
Garcinia hanburyi	1	1
Garcinia indica	1	1
Geum japonicum	1	1
Ginseng (Siberian)	1	1
Glycyrrhizin	1	1
Grapefruit Seed Extract	1	1
Graviola	1	1
Guggul	1	1
Hibiscus	1	1
Hyperforin	1	1
Icogenin	1	1
Juniper	1	1
Lactobacillus plantarum	1	1
Lemon Balm	1	1
Lemon Peel	1	1
Leonurine	1	1
Lichens	1	1
Lime: Key	1	1
Lingonberry	1	1
Lutein	1	1
Lychee	1	1
Maple Syrup	1	1
Marjoram	1	1
Milk Thistle	1	1
Mugwort	1	1
Myrrh	1	1
Nettle	1	1
Nexrutine (Phellodendrom)	1	1
Nisin	1	1
Olive	1	1
Olive Oil	1	1
Omega-3 Fatty Acids	1	1
Orange	1	1
Oregano	1	1
Oyster Mushroom	1	1
P-Coumaric Acid	1	1
Palm Oil	1	1
Papaya	1	1
Parsley	1	1
Passion Flower	1	1
Pea	1	1
Perillaldehyde	1	1
Phytoalexins	1	1
Pine Needle	1	1
Plum	1	1
Pomelo	1	1
Potato	1	1
Propolis: Bee	1	1
Punicic acid	1	1
Purslane	1	1
Pycnogenol (Pine Bark)	1	1
Radish	1	1
Rheum palmatum	1	1
Rice: Black	1	1
Rooibos	1	1
Royal Jelly	1	1
Rutin	1	1
Sage	1	1
Sandalwood	1	1
Sarsaparilla	1	1
Scopoletin	1	1
Sea buckthorn	1	1
Sesame Seeds	1	1
Sodium Bicarbonate	1	1
Syringic Acid	1	1
Tabebuia	1	1
Tea	1	1
Terminalia chebula	1	1
Tocotrienols	1	1
Turkey Tail Mushroom	1	1
Turmerones	1	1
Vegetables: All	1	1
Vitamin B-3 (Niacin)	1	1
Water: Deep Sea	1	1
Water: Deuterium Depleted	1	1
Water: Electrolyzed Reduced	1	1
Wheat Germ	1	1
beta-Carotene	1	1
β-ionone	1	1

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells.Jan 31, 2023

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Pubmed Data : Biomed Pharmacother. 2023 Feb ;158:114076. Epub 2022 Dec 13. PMID: 36516693

Article Published Date : Jan 31, 2023

Study Type : Human Study

Additional Links

Substances : Anthocyanins

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, NF-kappaB Inhibitor

[+]

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

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Pubmed Data : Curr Mol Med. 2012 Feb 1 ;12(2):163-76. PMID: 22280355

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Pubmed Data : PLoS One. 2016 ;11(1):e0146553. Epub 2016 Jan 11. PMID: 26752181

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Pubmed Data : Cancer Invest. 2010 May ;28(4):357-63. PMID: 19916793.

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Pubmed Data : PLoS One. 2016 ;11(3):e0150407. Epub 2016 Mar 2. PMID: 26934679

Article Published Date : Dec 31, 2015

Study Type : Human In Vitro, In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Breast Cancer, Cancer Metastasis

Pharmacological Actions : Anti-metastatic

Additional Keywords : Cancer Stem Cells

[+]

Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

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Pubmed Data : Oncol Lett. 2017 Apr ;13(4):2397-2402. Epub 2017 Feb 14. PMID: 28454410

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Pubmed Data : Pharmaceuticals (Basel). 2022 Jun 17 ;15(6). Epub 2022 Jun 17. PMID: 35745677

Article Published Date : Jun 16, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Lung Cancer

Pharmacological Actions : Anti-metastatic

[+]

Ginsenoside Rh4 suppresses metastasis of gastric cancer.Apr 08, 2022

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Pubmed Data : Phytomedicine. 2023 Nov ;120:155076. Epub 2023 Sep 9. PMID: 37716031

Article Published Date : Oct 31, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Icariin

Diseases : Cancer Metastasis, Prostate Cancer

Pharmacological Actions : Anti-metastatic

[+]

Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo.Jul 19, 2022

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Pubmed Data : Phytomedicine. 2022 Jul 20 ;102:154183. Epub 2022 May 20. PMID: 35636176

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Pubmed Data : Cancers (Basel). 2023 Jan 16 ;15(2). Epub 2023 Jan 16. PMID: 36672499

Article Published Date : Jan 15, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Asiatic Acid, Luteolin

Diseases : Cervical Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic

Additional Keywords : Natural Substance Synergy

[+]

The activation of SIRT1 by resveratrol reduces breast cancer metastasis to lung.Sep 28, 2023

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Pubmed Data : J Drug Target. 2023 Sep 29:1-31. Epub 2023 Sep 29. PMID: 37772906

Article Published Date : Sep 28, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Breast Cancer, Cancer Metastasis

Pharmacological Actions : Anti-metastatic, SIRT1 Activator

[+]

The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition.Apr 30, 2020

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Pubmed Data : Ann Transl Med. 2020 May ;8(9):590. PMID: 32566617

Article Published Date : Apr 30, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Lung Cancer

Pharmacological Actions : Anti-metastatic

Additional Keywords : Cancer Stem Cells

[+]

[+]

A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.Aug 07, 2016

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Pubmed Data : Sci Rep. 2017 Jan 30 ;7:41656. Epub 2017 Jan 30. PMID: 28134352

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Pubmed Data : Oncol Res. 2019 Aug 8 ;27(8):889-899. Epub 2019 Apr 2. PMID: 30940289

Article Published Date : Aug 07, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gleditsia sinensis

Diseases : Breast Cancer, Liver Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Plant Extracts

[+]

Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.Dec 31, 2018

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Ascorbic acid inhibits liver cancer growth and metastasis.Dec 31, 2020

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Pubmed Data : Front Pharmacol. 2021 ;12:726015. Epub 2021 Aug 24. PMID: 34504430

[+]

C60 fullerene as synergistic agent in tumor-inhibitory doxorubicin treatment.Nov 30, 2014

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Pubmed Data : BMC Complement Altern Med. 2015 ;15:216. Epub 2015 Jul 9. PMID: 26155792

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Pubmed Data : J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID: 26585812

Article Published Date : Nov 19, 2015

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Pubmed Data : Oncotarget. 2015 ;6(12):9854-76. PMID: 25918249

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Breast Cancer, Lung Cancer

Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents

Additional Keywords : Cancer Stem Cells, Epigenetic Modification In Cancer

[+]

Dietary delphinidin inhibits human colorectal cancer metastasis associating with upregulation of miR-204-3p and suppression of the integrin/FAK axisDec 11, 2019

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Pubmed Data : Food Chem Toxicol. 2016 Aug ;94:1-10. Epub 2016 May 17. PMID: 27224248

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Pubmed Data : Front Cell Dev Biol. 2020 ;8:606123. Epub 2020 Dec 23. PMID: 33425912

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Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

Article Published Date : Jan 31, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

[+]

Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo.Jul 18, 2017

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Pubmed Data : J Immunother. 2015 Jun ;38(5):185-96. PMID: 25962107

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei, Milk: Fermented

Diseases : Breast Cancer, Breast Cancer: Lung Metastasis, Cancer Metastasis

Pharmacological Actions : Anti-metastatic, Antiproliferative , Immunomodulatory

[+]

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine.Apr 14, 2012

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Pubmed Data : Clin Cancer Res. 2012 Apr 15 ;18(8):2220-9. Epub 2012 Feb 20. PMID: 22351692

Article Published Date : Apr 14, 2012

Study Type : Animal Study

Additional Links

Substances : Tocotrienol: Gamma, Vitamin E

Diseases : Gastric Cancer

Pharmacological Actions : Anti-metastatic, Bcl-2 protein down-regulation, Chemosensitizer, Cyclin D1 Down-Regulation, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Natural Substance/Drug Synergy

[+]

Fisetin could effectively suppress proliferation and metastasis of triple negative breast cancer.Dec 31, 2017

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Pubmed Data : J Agric Food Chem. 2009 Jun 10 ;57(11):5049-57. PMID: 19422227

Pubmed Data : Arch Biochem Biophys. 2020 Aug 30:108569. Epub 2020 Aug 30. PMID: 32877662

Article Published Date : Aug 29, 2020

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator

[+]

Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.Dec 31, 2014

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Pubmed Data : Nutrients. 2015 ;7(7):5065-87. Epub 2015 Jun 24. PMID: 26115086

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Pubmed Data : Phytomedicine. 2018 Nov 15 ;50:19-24. Epub 2018 Sep 18. PMID: 30466978

Article Published Date : Nov 14, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Prickly Pear Cactus

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

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Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

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Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3465-3477. PMID: 31432702

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Pubmed Data : Molecules. 2019 Oct 16 ;24(20). Epub 2019 Oct 16. PMID: 31623144

Article Published Date : Oct 15, 2019

Study Type : Animal Study, In Vitro Study

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Substances : Isoliquiritigenin

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic

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Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.Aug 04, 2019

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Pubmed Data : Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID: 31004603

Article Published Date : Aug 04, 2019

Study Type : Animal Study, In Vitro Study

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Substances : Isoliquiritigenin

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, MicroRNA modulator, Wnt/β-catenin signaling pathway modulation

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JWH-015 treatment significantly reduced primary tumor burden and metastasis of luciferase-tagged murine mammary carcinoma 4T1 cells.Dec 31, 2015

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Pubmed Data : Oncol Rep. 2017 Feb ;37(2):895-902. Epub 2016 Dec 12. PMID: 27959422

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Pubmed Data : J Transl Med. 2017 Feb 27 ;15(1):52. Epub 2017 Feb 27. PMID: 28241766

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Pubmed Data : Cancer Med. 2016 Jul 11. Epub 2016 Jul 11. PMID: 27401257

Article Published Date : Jul 10, 2016

Study Type : Animal Study

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Substances : Maitake Mushroom

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Plant Extracts

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Mangiferin treatment hold promise to reduce adverse toxicity and to mitigate therapeutic outcome of colorectal cancer.Dec 31, 2020

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Pubmed Data : J Exp Clin Cancer Res. 2019 Jan 3 ;38(1):2. Epub 2019 Jan 3. PMID: 30606241

Article Published Date : Jan 02, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Glioblastoma

Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative , Apoptotic

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View the Evidence: 2181 Abstracts with Anti-metastatic Research

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Anthocyanins reduce cell Invasion and migration through Akt/mTOR Downregulation and apoptosis activation in triple-negative breast cancer cells.Apr 13, 2023

A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Antitumor activity of fucoidan: a systematic review and meta-analysis.Nov 30, 2021

"Although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with BRCA-WT."Dec 31, 2004

A phase II study of docetaxel plus lycopene in metastatic castrate resistant prostate cancer.Oct 31, 2021

Bromelain has antimetastic protential as demonstrated in lung cancer cells - Article 1. Jan 01, 1988

FOLFIRI and FOLFOX6 chemotherapies result in a median progression free survival time of between 7.7 and 8.4 months.Jul 01, 2010

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

Magnolol and 5-fluorouracil synergy inhibition of metastasis of cervical cancer cells.Dec 31, 2023

Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells.Jan 31, 2023

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

These results indicate that whey protein concentrate might deplete tumour cells of glutathione and render them more vulnerable to chemotherapy.Oct 31, 1995

These results suggest a preventive effect of selenium on prostate cancer progression rather than on prostate cancer development.Jan 05, 2017

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

An extract of G. lucidum spores suppressed cholangiocarcinoma migration in vitro through inhibition of TGF-β1-induced EMT.May 14, 2016

Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.Aug 24, 2016

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

Cannabidiolic acid an active component in the cannabis plant offers potential therapeutic modality in the abrogation of cancer cell migration.Nov 14, 2012

Cordycepin inhibited migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.Dec 28, 2016

Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.Dec 31, 2014

Curcumin reduced Akt expression, cell proliferation, and migration in MDA-MB-231 breast cancer cells.Dec 31, 2015

Diallyl disulfide could be a promising anticancer agent for anti-metastatic treatment of esophageal-gastric junction adenocarcinoma in the future.Jan 31, 2018

Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.Sep 30, 2016

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Mandarin juice exerts in vitro antiproliferative effects on anaplastic thyroid carcinoma cells, associated with a reduction of migration.Sep 11, 2015

Nanoparticular thymoquinone attenuates angiogenesis and metastasis of triple-negative breast cancer.Mar 31, 2020

Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.Mar 31, 2017

Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.Dec 31, 2014

Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.Dec 14, 2016

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.Apr 10, 2017

Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.Dec 31, 2015

Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.Jan 01, 2018

THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells. Apr 30, 2010

The apple polyphenol phloretin inhibits colorectal cancer cell growth.Sep 13, 2016

The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.Dec 31, 2014

These results show that breast cancer stem cells, in both a canine and a human cell lines are responsive to melatonin treatment.Dec 31, 2015

Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

"Antineoplaston A in cancer therapy. (I)."Jan 01, 1977

"Phase I clinical studies of antineoplaston A5 injections."Jan 01, 1987

20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo.Apr 30, 2022

Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells.Jan 08, 2022

Anti-cancer activity of Cannabis sativa phytocannabinoids: molecular mechanisms and potential in the fight against ovarian cancer.Aug 31, 2022

Anti-cervical cancer activity of secondary metabolites of endophytic fungi from Ginkgo biloba.Dec 31, 2019

Antineoplaston A2 has anticancer effects. Jan 01, 1987

Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.Jan 01, 2003

Cinnamaldehyde decreases the invasion and u-PA expression of osteosarcoma by down-regulating the FAK signalling pathway.Jun 19, 2022

Ferulic acid nanocapsules as a promising treatment modality for colorectal cancer.May 31, 2022

Fucoxanthin inactivates the PI3K/Akt signaling pathway to mediate malignant biological behaviors of non-small cell lung cancer.Jul 14, 2022

Fucoxanthin inhibits gastric cancer lymphangiogenesis and metastasis.Aug 31, 2023

Gallic acid suppresses the progression of clear cell renal cell carcinoma.Jun 30, 2024

Ginsenoside Rh3 inhibits lung cancer metastasis.Jun 16, 2022

Ginsenoside Rh4 suppresses metastasis of gastric cancer.Apr 08, 2022

Glabridin inhibited the invasion of human liver cancer cells.May 31, 2014

Hyaluronidase inhibitor delphinidin inhibits cancer metastasis.Jun 27, 2024

Icariin inhibits prostate cancer bone metastasis and destruction.Oct 31, 2023

Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo.Jul 19, 2022

Induced PSIG expression by herbacetin contributes to suppressing the proliferation, migration, and invasion of melanoma cells.Jul 19, 2023

Isorhamnetin induces apoptosis and suppresses metastasis of human endometrial carcinoma Ishikawa cell.Oct 27, 2022

Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer.Oct 29, 2023

Limonin inhibits angiogenesis and metastasis of human breast cancer cells.Oct 31, 2020

Liposomal β-sitosterol suppresses metastasis of CT26/luc colon carcinoma.Jun 06, 2022

Magnolol regulates miR-200c-3p to inhibit epithelial-mesenchymal transition and retinoblastoma progression.Jan 31, 2023

Olive leaf extract inhibits metastatic melanoma spread through suppression of epithelial to mesenchymal transition.Sep 30, 2022

Piceatannol prevents colon cancer progression.May 25, 2022

Poria acid inhibit the growth and metastasis of renal cell carcinoma.May 29, 2024

Reduced HIF-1α stability induced by 6-gingerol inhibits lung cancer growth.Mar 23, 2022

Spirulina phycocyanin extract and its active components suppress epithelial-mesenchymal transition process in endometrial cancer.Jul 31, 2022

Synergistic combination of luteolin and asiatic acid on cervical cancer. Jan 15, 2023

The activation of SIRT1 by resveratrol reduces breast cancer metastasis to lung.Sep 28, 2023

The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition.Apr 30, 2020

The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.Apr 30, 2007

Anti-metastatic

View the Evidence:
2181 Abstracts with Anti-metastatic Research