Anti-metastatic

Name	AC	CK
Curcumin	98	129
Ginsenosides	53	88
Thymoquinone	36	45
EGCG (Epigallocatechin gallate)	27	42
Flavonoids	29	39
Quercetin	26	34
Resveratrol	27	34
Vitamin C	16	34
Polyphenols	25	31
Berberine	27	30
Melatonin	22	29
Apigenin	17	28
Honokiol	20	25
Sulforaphane	18	25
Luteolin	17	23
Shikonin	15	22
Reishi Mushroom	14	21
Huaier (Trametes robiniophila murr)	16	20
Fucoidan	15	19
Baicalein	16	18
Cannabidiol	12	17
Oridonin	11	17
Tanshinone IIA	14	17
Betulinic acid	11	16
Blueberry	9	16
Delta-tetrahydrocannabinol (THC)	9	15
Paeoniflorin	12	15
Piperlongumine	11	15
Pterostilbene	9	15
Selenium	6	15
Bromelain	4	14
Cannabinoids	12	14
Isoliquiritigenin	11	14
Kaempferol	8	14
Pineapple	3	14
Zerumbone	9	14
Beta-Elemene	11	13
Cannabis	8	13
Cucurbitacin B	12	13
Myricetin	8	13
Gingerol	10	12
Green Tea	8	12
Licorice	11	12
Nobiletin	10	12
Piperine	8	12
Pomegranate	10	12
Ursolic Acid	11	12
Cordyceps Militaris	6	11
Fisetin	9	11
Genistein	9	11
Lactoferrin	8	11
Anthocyanins	10	10
Bee Venom	9	10
Bisdemethoxycurcumin	6	10
Cannabinoids: Synthetic	6	10
Crocin	7	10
Deguelin	9	10
Ellagic Acid	7	10
Emodin	8	10
Mangiferin	8	10
Phellinus Linteus	8	10
Whey	1	10
Arctigenin	8	9
Astragaloside	7	9
Benzyl isothiocyanate	7	9
Garlic	5	9
Ginger	9	9
Magnolol	6	9
Parthenolide	4	9
Prunella vulgaris	7	9
Vitamin D	9	9
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	3	8
Apple Polyphenols	4	8
Cucurbitacin E	6	8
Curcumol	7	8
Fucoxanthin	4	8
Ginkgo biloba	5	8
Ginseng	3	8
Isothiocyanates	7	8
Naringenin	8	8
Phloretin	4	8
Puerarin	7	8
Silibinin	8	8
Wogonin	7	8
Xanthohumol	6	8
Astaxanthin	5	7
Bufalin	7	7
Catechin	6	7
Formononetin	7	7
Ginseng (Korean)	6	7
Grape	7	7
Nigella sativa (aka Black Seed)	6	7
Orange: Mandarin	3	7
Paeonol	5	7
Peony	6	7
Stilbenes	3	7
6-Shogaol	5	6
Aloe Vera	5	6
Artemisinin	5	6
Biochanin A	5	6
Chrysin	6	6
Holy Basil	4	6
Lotus	6	6
Lycopene	4	6
Oleuropein	6	6
Panax Notoginseng	5	6
Piceatannol	5	6
Saffron	5	6
Tangeretin	4	6
Theanine	4	6
Turmeric	5	6
Allicin	4	5
Andrographis	4	5
Berbamine	4	5
Black Raspberry	1	5
Carrot	4	5
Celastrol	5	5
Crocetin	4	5
Dandelion	4	5
Delphinidin	4	5
Demethoxycurcumin	4	5
Feverfew	1	5
Frankincense	4	5
Ligustrazine	4	5
Maitake Mushroom	3	5
Mistletoe	3	5
Mulberry	4	5
Phenethyl isothiocyanate	5	5
Rhubarb	5	5
Sesamin	4	5
Verbascoside	4	5
Vitamin E	4	5
Ashwagandha	4	4
Bee Propolis	3	4
DHA (Docosahexaenoic Acid)	3	4
Diosgenin	4	4
False Black Pepper	4	4
Gold (nanoparticles)	3	4
Hesperidin	3	4
Liquiritigenin	3	4
Lysine	2	4
MSM (Methylsulfonylmethane)	3	4
Mangosteen	3	4
Medicinal Mushrooms	3	4
Poria cocos	4	4
Proline	2	4
Punicalagin	4	4
Rosemaric Acid	4	4
S-Adenosylmethionine (SAMe)	3	4
Safflower	4	4
Schisandra	3	4
Sea Cucumber	2	4
Spirulina	3	4
Tomato	3	4
Wormwood	4	4
Agaricus Blazei	2	3
Alpha-Lipoic Acid	3	3
Amygdalin	3	3
Antineoplaston A5	1	3
Antineoplastons	1	3
Basil	2	3
Bergamot orange	2	3
Black Pepper	2	3
Black Tea	3	3
Burdock	3	3
Caffeic acid phenethyl ester	2	3
Chaga Mushroom (Inonotus obliquus)	3	3
Citrus Peel	3	3
Daisy	2	3
Eugenol	3	3
Ferulic acid	3	3
Fig	2	3
Fish Oil	2	3
Folate	2	3
Germanium	2	3
Homeopathic Medicine: All	2	3
Hydroxytyrosol	3	3
Krill	2	3
Lithospermum erythrorhizon	2	3
Lupeol	3	3
Manuka Honey	3	3
NAC (N-acetyl-L-cysteine)	2	3
Oleanolic acid	3	3
Oleocanthal	2	3
Peach	2	3
Phyllanthus amarus	3	3
Phyllanthus niruri (Stonebreaker)	3	3
Phyllanthus urinaria	3	3
Pine Bark Extract	3	3
Pomegranate Peel	3	3
Rose	3	3
St. Johns Wort	3	3
Strawberry	2	3
Sweet Potato	2	3
Tocotrienol: Delta	3	3
Tomatidine	3	3
Trichosanthes Kirilowii	2	3
Vanillin	3	3
acetyl-11-keto-beta-boswellic acid	2	3
Adlay	2	2
Amla Fruit	1	2
Amygdalin (laetrile)	2	2
Antrodia camphorata	2	2
Apple Pectin	1	2
Asparagus	2	2
Bacopa	2	2
Baking Soda	1	2
Bamboo	1	2
Beta Sitosterol	2	2
Bifidobacterium Longum	1	2
Bitter Melon	1	2
Boswellia	1	2
Broccoli	1	2
Cabbage	1	2
Caffeic Acid	2	2
Capsaicin	2	2
Cardamonin	2	2
Carnosine	2	2
Carnosol	1	2
Carvacrol	2	2
Chinese Skullcap	2	2
Chlorogenic Acid	1	2
Cinnamaldehyde	2	2
Cloudberry	1	2
Coenzyme Q10	1	2
Coffee	2	2
Coleus Forskohlii	1	2
Collards	1	2
Coptis chinensis	2	2
Curcumin: Lipidated	1	2
DIM (3,3'-diindolylmethane)	1	2
EPA (Eicosapentaenoic Acid)	1	2
Endocannabinoids	2	2
Essential Oils: Unspecified	1	2
Fenugreek	1	2
Fermented Foods and Beverages	1	2
Flaxseed	2	2
Gac	2	2
Gallic Acid	1	2
Genipin	2	2
Gleditsia sinensis	1	2
Goji	2	2
Guduchi	2	2
Gynostemma	2	2
Hibiscus sabdariffa	1	2
Honey	2	2
Hops	2	2
Hyaluronic Acid	1	2
Hydrangea	2	2
Jujube	1	2
Ketone Bodies	1	2
Kiwifruit	2	2
Lactobacillus casei	1	2
Lignans	2	2
Litchi	1	2
Long Pepper	1	2
Loquat Leaves	2	2
Marigold	2	2
Milk: Fermented	1	2
Moringa oleifera	2	2
Mushrooms: All	1	2
Noni	2	2
Nordihydroguaiaretic acid (NDGA)	1	2
Olive leaf extract	2	2
Onion	2	2
Palash	1	2
Panax Ginseng	2	2
Pantethine	1	2
Persimmon	2	2
Prickly Pear Cactus	1	2
Psychedelics:All	2	2
Raspberry	2	2
Red Clover	2	2
Red Sage	2	2
Red Yeast Rice	1	2
Rice Bran	2	2
Rosemary	1	2
Rosmarinic acid	2	2
Satsuma	1	2
Seaweed	2	2
Shiitake Mushroom	1	2
Silymarin	1	2
Sophora Flavescens	2	2
Soursop	2	2
Stearic Acid (stearate)	1	2
Syrian rue	2	2
Tetrahydrocurcumin	2	2
Theaflavins	2	2
Thistle	2	2
Thymol	1	2
Tocotrienol: Gamma	1	2
Toona sinensis	2	2
Triptolide	1	2
Urolithin A	2	2
Venom: Snake	2	2
Vinegar	1	2
Viruses: Beneficial	1	2
Vitamin A	2	2
Vitamin K	1	2
Vitamin K2	1	2
Walnut	2	2
White Mulberry	2	2
cottonseed oil (gossypol)	1	2
4-Shogaol	1	1
African Basil	1	1
Angelica	1	1
Apple	1	1
Artesunate	1	1
Artichoke	1	1
Asiatic Acid	1	1
Babchi	1	1
Bai Zhu	1	1
Beans: All	1	1
Berberis amurensis	1	1
Bergamot	1	1
Betaine	1	1
Betel	1	1
Bitter Apple	1	1
Black Cherry	1	1
Black Currant	1	1
Cafestol	1	1
Carnosic Acid	1	1
Catechols	1	1
Chamomile	1	1
Chili pepper	1	1
Chokeberry	1	1
Chrysanthemum Indicum	1	1
Citrus naringin	1	1
Coptidis rhizoma	1	1
Cordyceps sinensis	1	1
Coriandrum sativum	1	1
Corn Silk	1	1
Cruciferous Vegetables	1	1
Cucurbitacin D	1	1
Curcuminoids	1	1
Curry Leaves	1	1
Cyanidin	1	1
Cyanidin 3-glucoside	1	1
D-Limonene	1	1
Dracaena draco	1	1
Eggplant	1	1
Epimedium	1	1
Eriodictyol	1	1
Evening Primrose Oil	1	1
False Daisy	1	1
Fiber	1	1
Folic Acid	1	1
Fruit: All	1	1
Galbanic Acid	1	1
Ganoderma colossum	1	1
Garcinia Mangostana	1	1
Garcinia indica	1	1
Geum japonicum	1	1
Ginseng (Siberian)	1	1
Glycyrrhizin	1	1
Grape Seed Extract	1	1
Grapefruit	1	1
Graviola	1	1
Guggul	1	1
Hibiscus	1	1
Icogenin	1	1
Indole-3-Carbinol	1	1
Juniper	1	1
Lactobacillus plantarum	1	1
Lemon Balm	1	1
Lemon Peel	1	1
Lichens	1	1
Lutein	1	1
Lychee	1	1
Maple Syrup	1	1
Marjoram	1	1
Milk Thistle	1	1
Mugwort	1	1
Neem	1	1
Nettle	1	1
Nexrutine (Phellodendrom)	1	1
Olive	1	1
Olive Oil	1	1
Orange	1	1
Oregano	1	1
P-Coumaric Acid	1	1
Palm Oil	1	1
Papaya	1	1
Parsley	1	1
Passion Flower	1	1
Pea	1	1
Phytoalexins	1	1
Pine Needle	1	1
Plum	1	1
Pomelo	1	1
Potato	1	1
Proanthocyanidins	1	1
Probiotics	1	1
Propolis: Bee	1	1
Punicic acid	1	1
Purslane	1	1
Radish	1	1
Rheum palmatum	1	1
Rice: Black	1	1
Rooibos	1	1
Rutin	1	1
Salvia miltiorrhiza	1	1
Sandalwood	1	1
Sarsaparilla	1	1
Seaweed: Brown	1	1
Sesame Seeds	1	1
Sodium Bicarbonate	1	1
Tabebuia	1	1
Tannic Acid	1	1
Tea	1	1
Tocotrienols	1	1
Turmerones	1	1
Vegetables: All	1	1
Vitexins	1	1
Water: Deep Sea	1	1
Water: Deuterium Depleted	1	1
Water: Electrolyzed Reduced	1	1
Wheat Germ	1	1
beta-Carotene	1	1
β-ionone	1	1

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Pubmed Data : PLoS One. 2016 ;11(1):e0146553. Epub 2016 Jan 11. PMID: 26752181

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Pubmed Data : Cancer Invest. 2010 May ;28(4):357-63. PMID: 19916793.

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Pubmed Data : PLoS One. 2016 ;11(3):e0150407. Epub 2016 Mar 2. PMID: 26934679

Article Published Date : Dec 31, 2015

Study Type : Human In Vitro, In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Breast Cancer, Cancer Metastasis

Pharmacological Actions : Anti-metastatic

Additional Keywords : Cancer Stem Cells

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Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

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Pubmed Data : Oncol Lett. 2017 Apr ;13(4):2397-2402. Epub 2017 Feb 14. PMID: 28454410

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Pubmed Data : J Ginseng Res. 2022 May ;46(3):396-407. Epub 2021 Jul 12. PMID: 35600769

Article Published Date : Apr 30, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

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Anti-cancer activity of Cannabis sativa phytocannabinoids: molecular mechanisms and potential in the fight against ovarian cancer.Aug 31, 2022

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Pubmed Data : Cancers (Basel). 2022 Sep 1 ;14(17). Epub 2022 Sep 1. PMID: 36077833

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The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.Apr 30, 2007

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Pubmed Data : J Altern Complement Med. 2007 May ;13(4):443-5. PMID: 17532738

Article Published Date : Apr 30, 2007

Study Type : Human: Case Report

Additional Links

Substances : Mistletoe

Diseases : Cancer Metastasis, Liver Cancer: Metastatic, Melanoma, Skin Cancer

Pharmacological Actions : Anti-metastatic, Anti-Tumor, Antineoplastic Agents

Additional Keywords : Plant Extracts

[+]

This study demonstrated the successful inhibitory effect of AP-ZEONE on metastatic breast cancer cells.Dec 31, 2021

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Pubmed Data : Front Pharmacol. 2022 ;13:946161. Epub 2022 Sep 5. PMID: 36133807

Article Published Date : Dec 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Apple Pectin , Zataria multiflora

Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cancer Metastasis

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Essential Oils

[+]

Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.Dec 31, 2014

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A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.Aug 07, 2016

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Pubmed Data : Sci Rep. 2017 Jan 30 ;7:41656. Epub 2017 Jan 30. PMID: 28134352

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Pubmed Data : Oncol Res. 2019 Aug 8 ;27(8):889-899. Epub 2019 Apr 2. PMID: 30940289

Article Published Date : Aug 07, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gleditsia sinensis

Diseases : Breast Cancer, Liver Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Plant Extracts

[+]

Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.Dec 31, 2018

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Additional Keywords : Cannabinoid Receptors, Natural Substance Synergy

[+]

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.Apr 01, 2012

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Pubmed Data : FASEB J. 2012 Apr ;26(4):1535-48. Epub 2011 Dec 23. PMID: 22198381

Article Published Date : Apr 01, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Cancer Metastasis, Lung Cancer

Pharmacological Actions : Anti-metastatic, Intracellular adhesion molecule-1 (ICAM-1)

[+]

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

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Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222

Article Published Date : Nov 30, 2006

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabinoids: Synthetic

Diseases : Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Cannabinoid Receptors, Selective Cytotoxicity

[+]

Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.Dec 31, 2018

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Pubmed Data : BMC Complement Altern Med. 2015 ;15:216. Epub 2015 Jul 9. PMID: 26155792

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Cucurbitacin E can be considered to be a promising anti-cancer agent for osteosarcoma.Sep 20, 2016

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Pubmed Data : Biosci Rep. 2016 Sep 21. Epub 2016 Sep 21. PMID: 27653525

Article Published Date : Sep 20, 2016

Study Type : Animal Study

Additional Links

Substances : Cucurbitacin E

Diseases : Osteosarcoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

Cucurbitacin E inhibits the Yes associated protein signaling pathway and suppresses brain metastasis of human non small cell lung cancer in a murine model.Jul 31, 2019

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Pubmed Data : J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID: 26585812

Article Published Date : Nov 19, 2015

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Pubmed Data : Oncotarget. 2015 ;6(12):9854-76. PMID: 25918249

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Breast Cancer, Lung Cancer

Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents

Additional Keywords : Cancer Stem Cells, Epigenetic Modification In Cancer

[+]

Dietary delphinidin inhibits human colorectal cancer metastasis associating with upregulation of miR-204-3p and suppression of the integrin/FAK axisDec 11, 2019

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Pubmed Data : Food Chem Toxicol. 2016 Aug ;94:1-10. Epub 2016 May 17. PMID: 27224248

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Pubmed Data : Bull Exp Biol Med. 2020 Jul ;169(3):378-382. Epub 2020 Aug 4. PMID: 32749562

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Pubmed Data : Front Cell Dev Biol. 2020 ;8:606123. Epub 2020 Dec 23. PMID: 33425912

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Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

Article Published Date : Jan 31, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

[+]

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Pubmed Data : J Agric Food Chem. 2009 Jun 10 ;57(11):5049-57. PMID: 19422227

Pubmed Data : Arch Biochem Biophys. 2020 Aug 30:108569. Epub 2020 Aug 30. PMID: 32877662

Article Published Date : Aug 29, 2020

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator

[+]

Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.Dec 31, 2014

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Pubmed Data : Nutrients. 2015 ;7(7):5065-87. Epub 2015 Jun 24. PMID: 26115086

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Pubmed Data : Phytomedicine. 2018 Nov 15 ;50:19-24. Epub 2018 Sep 18. PMID: 30466978

Article Published Date : Nov 14, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Prickly Pear Cactus

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

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Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3465-3477. PMID: 31432702

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Pubmed Data : Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID: 31004603

Article Published Date : Aug 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, MicroRNA modulator, Wnt/β-catenin signaling pathway modulation

[+]

JWH-015 treatment significantly reduced primary tumor burden and metastasis of luciferase-tagged murine mammary carcinoma 4T1 cells.Dec 31, 2015

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Pubmed Data : Oncol Rep. 2017 Feb ;37(2):895-902. Epub 2016 Dec 12. PMID: 27959422

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Pubmed Data : J Transl Med. 2017 Feb 27 ;15(1):52. Epub 2017 Feb 27. PMID: 28241766

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Pubmed Data : Cancer Med. 2016 Jul 11. Epub 2016 Jul 11. PMID: 27401257

Article Published Date : Jul 10, 2016

Study Type : Animal Study

Additional Links

Substances : Maitake Mushroom

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Plant Extracts

[+]

Mangiferin treatment hold promise to reduce adverse toxicity and to mitigate therapeutic outcome of colorectal cancer.Dec 31, 2020

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Pubmed Data : Front Pharmacol. 2021 ;12:670167. Epub 2021 Dec 3. PMID: 34924998

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Colorectal Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic,

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View the Evidence: 1841 Abstracts with Anti-metastatic Research

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A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Antitumor activity of fucoidan: a systematic review and meta-analysis.Nov 30, 2021

"Although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with BRCA-WT."Dec 31, 2004

A phase II study of docetaxel plus lycopene in metastatic castrate resistant prostate cancer.Oct 31, 2021

Bromelain has antimetastic protential as demonstrated in lung cancer cells - Article 1. Jan 01, 1988

FOLFIRI and FOLFOX6 chemotherapies result in a median progression free survival time of between 7.7 and 8.4 months.Jul 01, 2010

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

These results indicate that whey protein concentrate might deplete tumour cells of glutathione and render them more vulnerable to chemotherapy.Oct 31, 1995

These results suggest a preventive effect of selenium on prostate cancer progression rather than on prostate cancer development.Jan 05, 2017

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

An extract of G. lucidum spores suppressed cholangiocarcinoma migration in vitro through inhibition of TGF-β1-induced EMT.May 14, 2016

Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.Aug 24, 2016

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

Cannabidiolic acid an active component in the cannabis plant offers potential therapeutic modality in the abrogation of cancer cell migration.Nov 14, 2012

Cordycepin inhibited migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.Dec 28, 2016

Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.Dec 31, 2014

Curcumin reduced Akt expression, cell proliferation, and migration in MDA-MB-231 breast cancer cells.Dec 31, 2015

Diallyl disulfide could be a promising anticancer agent for anti-metastatic treatment of esophageal-gastric junction adenocarcinoma in the future.Jan 31, 2018

Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.Sep 30, 2016

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Mandarin juice exerts in vitro antiproliferative effects on anaplastic thyroid carcinoma cells, associated with a reduction of migration.Sep 11, 2015

Nanoparticular thymoquinone attenuates angiogenesis and metastasis of triple-negative breast cancer.Mar 31, 2020

Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.Mar 31, 2017

Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.Dec 31, 2014

Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.Dec 14, 2016

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.Apr 10, 2017

Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.Dec 31, 2015

Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.Jan 01, 2018

THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells. Apr 30, 2010

The apple polyphenol phloretin inhibits colorectal cancer cell growth.Sep 13, 2016

The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.Dec 31, 2014

These results show that breast cancer stem cells, in both a canine and a human cell lines are responsive to melatonin treatment.Dec 31, 2015

Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

"Antineoplaston A in cancer therapy. (I)."Jan 01, 1977

"Phase I clinical studies of antineoplaston A5 injections."Jan 01, 1987

20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo.Apr 30, 2022

Anti-cancer activity of Cannabis sativa phytocannabinoids: molecular mechanisms and potential in the fight against ovarian cancer.Aug 31, 2022

Anti-cervical cancer activity of secondary metabolites of endophytic fungi from Ginkgo biloba.Dec 31, 2019

Antineoplaston A2 has anticancer effects. Jan 01, 1987

Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.Jan 01, 2003

Cinnamaldehyde decreases the invasion and u-PA expression of osteosarcoma by down-regulating the FAK signalling pathway.Jun 19, 2022

Ferulic acid nanocapsules as a promising treatment modality for colorectal cancer.May 31, 2022

Fucoxanthin inactivates the PI3K/Akt signaling pathway to mediate malignant biological behaviors of non-small cell lung cancer.Jul 14, 2022

Ginsenoside Rh3 inhibits lung cancer metastasis.Jun 16, 2022

Ginsenoside Rh4 suppresses metastasis of gastric cancer.Apr 08, 2022

Glabridin inhibited the invasion of human liver cancer cells.May 31, 2014

Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo.Jul 19, 2022

Olive leaf extract inhibits metastatic melanoma spread through suppression of epithelial to mesenchymal transition.Sep 30, 2022

Piceatannol prevents colon cancer progression.May 25, 2022

Reduced HIF-1α stability induced by 6-gingerol inhibits lung cancer growth.Mar 23, 2022

Spirulina phycocyanin extract and its active components suppress epithelial-mesenchymal transition process in endometrial cancer.Jul 31, 2022

The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition.Apr 30, 2020

The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.Apr 30, 2007

This study demonstrated the successful inhibitory effect of AP-ZEONE on metastatic breast cancer cells.Dec 31, 2021

Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.Dec 31, 2014

Targeted delivery of honokiol by zein/hyaluronic acid core-shell nanoparticles to suppress breast cancer growth and metastasis.Jul 14, 2020

"Anti-metastasis effect of thymoquinone on human pancreatic cancer"Jul 31, 2011

"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."Mar 01, 2005

(-)-Epigallocatechin-3-gallate (EGCG) can inhibit the proliferation and invasiveness and induce apoptosis in nasopharyngeal carcinoma cells.Dec 31, 2014

10-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models.Aug 05, 2020

10-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo.Sep 21, 2017

20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.Dec 31, 2018

6-Shogaol decreases cancer-induced up-regulation of CCL2 in TADCs, preventing the enhancing effects of TADCs on tumorigenesis and metastatic properties in A549 and MDA-MB-231 cells.Feb 17, 2015

A Huaier polysaccharide reduced metastasis of human hepatocellular carcinoma.Jul 31, 2015

A lipid-soluble ginseng extract potently inhibited invasion and migration of B16F10 mouse melanoma cells in a dose-dependent manner.Dec 31, 2014

A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits angiogenesis of tumor cells.Dec 01, 2006

A novel combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy could be used to manage metastatic cancers.Dec 31, 2014

A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.Aug 07, 2016

A polysaccharide from Punica granatum has an inhibitory effect on metastasis. May 24, 2017

A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.Mar 17, 2017

Anti-metastatic

View the Evidence:
1841 Abstracts with Anti-metastatic Research