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Antiproliferative
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713 Substances Researched for Antiproliferative
Name
AC
CK
Focus
Curcumin
342
461
Resveratrol
109
142
Ginsenosides
95
120
EGCG (Epigallocatechin gallate)
69
112
Flavonoids
64
81
Sulforaphane
47
81
Polyphenols
49
69
Apigenin
41
67
Vitamin C
45
65
Berberine
48
59
Cannabinoids
40
58
Green Tea
25
58
Thymoquinone
45
58
Cucurbitacin B
41
56
Quercetin
48
56
Tanshinone IIA
50
55
Catechin
31
53
Melatonin
31
50
Shikonin
27
50
Genistein
43
47
Indole-3-Carbinol
32
45
Vitamin D
33
45
Pterostilbene
30
42
Fucoidan
33
41
Honokiol
29
40
Beta-Elemene
35
39
Flaxseed
13
39
Deguelin
33
36
Lycopene
15
36
Fisetin
27
35
Silibinin
25
35
Cannabidiol
23
34
Ellagic Acid
23
34
Ursolic Acid
24
34
Luteolin
27
33
Medicinal Mushrooms
11
33
Xanthohumol
29
33
Anthocyanins
25
32
Grape Seed Extract
19
32
Wogonin
18
30
Artemisinin
18
29
Chaga Mushroom (Inonotus obliquus)
18
29
Huaier (Trametes robiniophila murr)
23
28
Delta-tetrahydrocannabinol (THC)
17
27
Isoliquiritigenin
20
27
Naringenin
15
27
Ginkgo biloba
18
26
Water: Deuterium Depleted
7
26
Parthenolide
18
25
Ginger
18
24
Reishi Mushroom
20
24
Lignans
9
23
Vitamin E
14
23
Gingerol
16
22
Isoflavones
15
22
Nigella sativa (aka Black Seed)
11
22
Baicalein
17
21
Chrysin
18
21
Phloretin
14
20
Caffeic Acid
8
19
Cannabis
12
19
Piperlongumine
14
19
Astaxanthin
13
18
Cannabinoids: Synthetic
12
18
Garlic
15
18
Lichens
18
18
Myricetin
16
18
Paeoniflorin
15
18
Turmeric
13
18
Carnosic Acid
14
17
NAC (N-acetyl-L-cysteine)
7
17
Piperine
12
17
Tocotrienol: Gamma
8
17
6-Shogaol
12
16
Fish Oil
5
16
Lithospermum erythrorhizon
6
16
Phenethyl isothiocyanate
11
16
Pomegranate
14
16
Caffeic acid phenethyl ester
11
15
Camel Milk
7
15
Emodin
13
15
Enterolactone
4
15
Fermented Foods and Beverages
12
15
Ginseng (Korean)
9
15
Nobiletin
12
15
Omega-3 Fatty Acids
9
15
Rosemary
10
15
Stilbenes
14
15
Vitamin K2
6
15
Arctigenin
9
14
Astragaloside
13
14
Berbamine
10
14
Graviola
8
14
Lotus
11
14
Oridonin
9
14
Rhubarb
6
14
Strawberry
4
14
Asiatic Acid
12
13
Bitter Orange
4
13
Chokeberry
9
13
Crocin
12
13
Gallic Acid
10
13
Gold (nanoparticles)
11
13
Mangosteen
7
13
Moringa oleifera
9
13
Mushrooms: All
10
13
Oleuropein
11
13
Psychedelics:All
11
13
Soy Protein
7
13
Spirulina
6
13
Tetrahydrocurcumin
7
13
Toona sinensis
6
13
Aloe Vera
9
12
Ashwagandha
9
12
Black Pepper
8
12
Blueberry
9
12
Carrot
7
12
Cinnamon
9
12
Frankincense
6
12
Fucoxanthin
7
12
Grape
10
12
Licorice
11
12
Piceatannol
11
12
Puerarin
11
12
Raspberry
9
12
Sesamin
6
12
Vitamin E: Gamma-Tocopherol
5
12
Wheat Grass
9
12
Adlay
10
11
Anandamide
6
11
Bufalin
10
11
Cruciferous Vegetables
7
11
Cucurbitacin E
10
11
Diosmin
7
11
Fiber
7
11
Garlic: Aged
5
11
Hesperidin
7
11
Homeopathic Medicine: All
9
11
Kaempferol
10
11
Lysine
5
11
Nexrutine (Phellodendrom)
6
11
Prunella vulgaris
9
11
Pycnogenol (Pine Bark)
2
11
Syrian rue
9
11
Zerumbone
7
11
Allicin
9
10
Antrodia camphorata
5
10
Apples
8
10
Benzyl isothiocyanate
8
10
Caffeine
1
10
Cryptoxanthin
1
10
Ginseng
6
10
Gynostemma
8
10
Magnolol
8
10
Mangiferin
9
10
Motherwort
1
10
Mulberry
4
10
Nettle
8
10
Red Sage
9
10
Selenium
7
10
Tomato
7
10
Walnut
9
10
Amla Fruit
3
9
Apple Polyphenols
5
9
Bee Propolis
9
9
Betulinic acid
9
9
Cucurbitacin D
8
9
Diosgenin
9
9
Garcinia indica
4
9
Isothiocyanates
7
9
Lupeol
7
9
Olive leaf extract
7
9
Shallot
8
9
Soy
5
9
Tangeretin
8
9
Thistle
7
9
Vitamin A
7
9
Vitamin K
7
9
Amygdalin
6
8
Artesunate
8
8
Avocado
4
8
Beans: All
8
8
Bee Venom
6
8
Black Raspberry
4
8
Black Tea
6
8
Calcium
4
8
Carotenoids
6
8
Citrus Peel
7
8
Cranberry
7
8
DHA (Docosahexaenoic Acid)
6
8
Daidzein
6
8
Dandelion
6
8
Delphinidin
7
8
Fig
6
8
Genipin
5
8
MSM (Methylsulfonylmethane)
6
8
Maitake Mushroom
5
8
Mistletoe
7
8
Noni
7
8
Phellinus Linteus
6
8
Probiotics
5
8
Rosemaric Acid
7
8
Rutin
6
8
Shiitake Mushroom
6
8
Sprouts
7
8
Tocotrienol: Delta
7
8
phytoestrogens
5
8
Bael
4
7
Bisdemethoxycurcumin
3
7
Burdock
6
7
Chinese Skullcap
5
7
Damnacanthal
7
7
Demethoxycurcumin
6
7
Evodiamine
6
7
Hydroxytyrosol
7
7
Kahweol
7
7
Milk Thistle
5
7
Olive
6
7
Orange
7
7
Orange: Mandarin
2
7
Panax Notoginseng
6
7
Pine Needle
6
7
Piperidines
6
7
Prickly Pear Cactus
6
7
Saffron
5
7
Spinach
4
7
Thyme
6
7
Verbascoside
5
7
Vitamin E: Gamma-tocotrienol
7
7
Whey
5
7
Bai Zhu
5
6
Bergamot orange
5
6
Bloodroot
2
6
Butyrate
5
6
Carnosol
6
6
Catechols
5
6
Chlorogenic Acid
6
6
Citrus naringin
5
6
Cyanidin 3-glucoside
4
6
Endocannabinoids
5
6
Eucalyptus
5
6
Gac
4
6
Goji
6
6
Honey
5
6
Lactobacillus probiotics
2
6
Limonoids
2
6
Mustard: Field/Turnip
2
6
Oleanolic acid
4
6
Panax Ginseng
4
6
Persimmon
5
6
Proline
4
6
Pumpkin
2
6
Rose
5
6
Sage
5
6
Seaweed
5
6
Silver (nanoparticles)
6
6
Sweet Potato
4
6
Sweet Potato: Purple
4
6
Urolithin A
5
6
Vitamin E: delta-tocopherol
4
6
Arginine
3
5
Beet
5
5
Bitter Melon
5
5
Black Cohosh
5
5
Capsaicin
5
5
Carvacrol
4
5
Chrysanthemum Indicum
5
5
Crocetin
5
5
Curcumin: Degradiation byproducts
1
5
D-Limonene
5
5
Daisy
4
5
Enterodiol
3
5
Ferulic acid
5
5
Ginseng (Siberian)
4
5
Hops
5
5
Inositol Hexaphosphate
4
5
Kava Kava
3
5
Magnolia
4
5
Olive Oil
4
5
Oregano
4
5
P-Coumaric Acid
5
5
Panaxadiol
1
5
Pomegranate Peel
5
5
Red Yeast Rice
3
5
Silymarin
4
5
Sophora Flavescens
4
5
White Tea
4
5
acetyl-11-keto-beta-boswellic acid
3
5
beta-Carotene
4
5
Apple
3
4
Blackberry
3
4
Broccoli
4
4
Cordyceps Militaris
4
4
Coumestrol
4
4
Curcumol
2
4
Curry Leaves
3
4
EPA (Eicosapentaenoic Acid)
3
4
False Black Pepper
4
4
Flaxseed Oil
2
4
Folate
3
4
Geraniol
4
4
Geranium
2
4
Ginseng (American)
4
4
Gotu Kola
3
4
Guava
3
4
Holy Basil
3
4
Isoquercitrin
2
4
Jambul
2
4
Lactobacillus casei
2
4
Ligustrazine
4
4
Litchi
4
4
Manuka Honey
3
4
Myo-inositol
2
4
Palash
3
4
Papaya
4
4
Parsley
4
4
Peach
4
4
Punicalagin
4
4
Rice Bran
4
4
Sea Cucumber
2
4
Sea buckthorn
4
4
Shemamruthaa
2
4
Solanum nigrum (black nightshade)
2
4
St. Johns Wort
4
4
Stearic Acid (stearate)
2
4
Tea
3
4
Theanine
2
4
Trichosanthes Kirilowii
3
4
Wormwood
3
4
Acai
2
3
Agaricus Blazei
2
3
Agrimony
1
3
Andrographis
2
3
Apple Pectin
2
3
Asparagus
3
3
Bamboo
2
3
Berries: All
3
3
Beta Sitosterol
3
3
Bilberry
2
3
Bile salts
2
3
Black Bean
3
3
Boswellia
2
3
CLA (Conjugated Linoleic Acid)
2
3
Chamomile
3
3
Chickpea
3
3
Chlorella (Algae)
2
3
Cocoa
3
3
Collagen
2
3
Corn Silk
3
3
Curcuma Purpurascens
2
3
Essential Oils: Unspecified
2
3
Fenugreek
3
3
Feverfew
3
3
Fruit Peel
2
3
Hawthorn
3
3
Hydrogen Peroxide
3
3
Lemon
2
3
Loquat
2
3
Lychee
3
3
Maple Syrup
3
3
Modified Arabinoxylan Rice Bran (MGN-3)
2
3
Mung Bean
2
3
Oats
3
3
Onion
3
3
Oyster Mushroom
3
3
Peanut
3
3
Perilla
3
3
Phyllanthus urinaria
3
3
Plantago
2
3
Plum
3
3
Polyunsaturated Fatty Acids (PUFAs)
2
3
Potato
3
3
Pumpkin Seeds
3
3
Purslane
3
3
Raisins
3
3
Rose Hips
3
3
Rosmarinic acid
2
3
Royal Jelly
2
3
Ruta Graveolens
3
3
S-Adenosylmethionine (SAMe)
2
3
Saccharomyces Boulardii
2
3
Stevia
3
3
Tannic Acid
3
3
Tarragon
2
3
Theaflavins
3
3
Thiamine (B-1)
2
3
Tualang Honey
2
3
Venom: Snake
3
3
Vitexins
3
3
Wheat Bran
2
3
White Button Mushroom
2
3
Xanthones
3
3
18β-Glycyrrhetinic Acid
2
2
Alpha Linolenic Acid
1
2
Alpinia galanga
2
2
Anthurium schlechtendalii
1
2
Argan Oil
2
2
Arugula
1
2
Avenanthramides
2
2
Azelaic Acid
1
2
Bacopa
2
2
Barley
1
2
Bay leaf
2
2
Bergamot
2
2
Betaine
2
2
Bifidobacterium Longum
1
2
Black Currant
2
2
Bromelain
2
2
Cafestol
2
2
Camptothecin
1
2
Cannabigerol
1
2
Capparis spinosa (caper)
2
2
Carnitine
1
2
Cat's Claw
2
2
Chinense Herbal Formula: Huang-lian-jie-du-decoction
1
2
Cinnamic acid
1
2
Cleavers
2
2
Cloudberry
1
2
Codonopsis lanceolata
1
2
Coffee
2
2
Cranberry Proanthocyanidins
1
2
Creatine
1
2
Cucumber
1
2
Curcuma phaeocaulis
2
2
Diallyl sulfide
2
2
Dimethyl trisulfide (DMTS)
2
2
Elderberry
2
2
Elm tree
1
2
Eriodictyol
1
2
Eugenol
2
2
Folic Acid
1
2
Goldenthread
2
2
Guarana
2
2
Guduchi
2
2
Hazelnut
2
2
Helenalin
2
2
Hibiscus sabdariffa
2
2
Homeopathic Medicine: Sabal serrulata
1
2
Huperzine
2
2
Inulin
1
2
Japanese cypress
2
2
Jujube
2
2
Kaempferia parviflora
2
2
Kefir
2
2
Ketone Bodies
1
2
Kimchi
2
2
King trumpet mushroom
1
2
Kudzu
2
2
Lactobacillus Brevis
1
2
Lactobacillus plantarum
1
2
Lactobacillus rhamnosus
1
2
Lemon Balm
2
2
Long Pepper
1
2
Lutein
1
2
Magnesium
1
2
Mango
1
2
Methionine
1
2
Milk: Fermented
1
2
Miso
1
2
Modified Citrus Pectin
1
2
Myrrh
1
2
Nitrite
1
2
Noni leaf extract
1
2
Oleocanthal
2
2
Oyster Mushroom: Golden
2
2
Pantethine
1
2
Passion Flower
1
2
Pear
2
2
Pecan
1
2
Peppermint
2
2
Phyllanthus amarus
2
2
Phyllanthus emblica
2
2
Phyllanthus niruri (Stonebreaker)
2
2
Pine Bark Extract
2
2
Plant Ribonuclease
1
2
Plantain
1
2
Pleurotus nebrodensis
2
2
Potato: Pigmented
1
2
Proanthocyanidins
2
2
Pueraria mirifica
2
2
Punicic acid
2
2
Rambutan
2
2
Rooibos
2
2
Rubia Cordifolia
1
2
Salicylic acid
1
2
Sandalwood
2
2
Saturated fatty acids
1
2
Saw Palmetto
1
2
Seaweed: Brown
2
2
Sesame Seeds
2
2
Soursop
2
2
Stigmasterol
1
2
Terminalia
2
2
Thuja
1
2
Tocotrienol: Alpha
1
2
Tocotrienols
2
2
Tongkat Ali
2
2
Traditional Chinese Medicine: Mylabris
2
2
Turmerones
2
2
Valerian
1
2
Vanillin
2
2
Venom: Toad
2
2
Viruses: Beneficial
1
2
Vitamin B-12
1
2
Vitamin C: Intravenous
2
2
Vitamin E: alpha tocopherol
2
2
Watercress
1
2
Wheat: Fermented
2
2
Yerba Santa
1
2
2-Methoxyestradiol
1
1
Acorus calamus
1
1
Aleurone
1
1
Algae
1
1
Allomelanins
1
1
Amygdalin (laetrile)
1
1
Angelica
1
1
Antineoplaston A3
1
1
Antineoplaston A5
1
1
Apricot Kernel
1
1
Arabinoxylans
1
1
Argania spinosa (Argan)
1
1
Arnica
1
1
Artichoke
1
1
Bacillus coagulans
1
1
Barberry
1
1
Bean: Black Pigmented
1
1
Beer
1
1
Belamcanda chinensis
1
1
Berberis amurensis
1
1
Beta-Caryophyllene
1
1
Beta-sesquiphellandrene
1
1
Betanins
1
1
Bifidobacterium Bifidum
1
1
Biochanin A
1
1
Black Soy
1
1
Black Tea Theaflavins
1
1
Bran
1
1
Brussel sprouts
1
1
Buckwheat
1
1
Cabbage
1
1
Canthaxanthin
1
1
Capsanthin
1
1
Capsorubin
1
1
Carsonic Acid
1
1
Cautleya gracilis
1
1
Celery
1
1
Celery seed
1
1
Cherry: All Varieties
1
1
Chili pepper
1
1
Chitosan
1
1
Citrus aurantium
1
1
Coconut
1
1
Codonopsis pilosula
1
1
Colloidal Silver
1
1
Coptidis rhizoma
1
1
Coptis chinensis
1
1
Cordyceps sinensis
1
1
Coriandrum sativum
1
1
Corn: Purple
1
1
Corydalis Yanhusuo
1
1
Crimini Mushroom
1
1
Curcuma Longa
1
1
Curcuminoids
1
1
Cyperus rotundus
1
1
Daikon radish
1
1
Dibenzoylmethane (DBM)
1
1
Dill
1
1
Diosmetin
1
1
Docosahexaenoic acid (DHA)
1
1
Dopa bean
1
1
Dragon Fruit
1
1
Dulse
1
1
Echinacea
1
1
Egg
1
1
Eggplant
1
1
Eleutherococcus senticosus
1
1
Epimedium
1
1
Erucin
1
1
Estradiol (E(2))
1
1
Evening Primrose Oil
1
1
Fennel
1
1
Flavan-3-ols
1
1
Flax Straw
1
1
Garcinia Mangostana
1
1
Garcinia xanthochymus
1
1
Gastrodin
1
1
Geum japonicum
1
1
Ginseng (Asian)
1
1
Gleditsia sinensis
1
1
Glycyrrhizin
1
1
Gold
1
1
Grapefruit
1
1
Grapes
1
1
Hemp Seed
1
1
Hibiscus rosa-sinensis
1
1
Honeybush
1
1
Honeydew (melon)
1
1
Horehound
1
1
Horsetail
1
1
Hu Zhang (Polygonum cuspidatum)
1
1
Humic Acid
1
1
Hyperforin
1
1
Indian Gooseberry
1
1
Iodine
1
1
Japanese Herbal Formula: Juzen-taiho-to
1
1
Juniper
1
1
Kanuka Honey
1
1
Kiwifruit
1
1
Krill
1
1
Lactobacillus Acidophilus
1
1
Lactobacillus fermentum
1
1
Lactobacillus paracasei
1
1
Lactobacillus rhamnosus GG
1
1
Lactoferrin
1
1
Larrea divaricata
1
1
Legumes
1
1
Lemongrass
1
1
Lettuce
1
1
Lime: Key
1
1
Lingonberry
1
1
Linoleic acid
1
1
Lion's Mane (Hericium Erinaceus)
1
1
Maca
1
1
Marjoram
1
1
Matairesinol
1
1
Melissa (Lemonbalm)
1
1
Menthol
1
1
Mucuna pruriens (aka Velvet Beans)
1
1
Mustard Oil
1
1
Myrica rubra
1
1
Neem
1
1
Nicotinamide
1
1
Nuts
1
1
OPC (Oligomeric Proanthocyanidins)
1
1
Oak
1
1
Okra
1
1
Omega-5 fatty acids
1
1
Oolong tea
1
1
Organosulfur Compounds
1
1
Ox Bile Extract
1
1
Oyster Mushroom: Indian
1
1
Palm Oil
1
1
Palmitoylethanolamide
1
1
Pau D'Arco
1
1
Pea
1
1
Pelargonium sidoides
1
1
Peony
1
1
Phytoalexins
1
1
Phytosterols
1
1
Pine Cone
1
1
Pinellia
1
1
Placenta Extract (or Stem Cells)
1
1
Plant Stem Cells
1
1
Plant Sterols/Stanols
1
1
Plantago major
1
1
Podophyllum hexandrum
1
1
Pomegranate Polyphenols
1
1
Pomegranate Seed
1
1
Portabella Mushroom
1
1
Procyanidin B2
1
1
Propolis: Bee
1
1
Propolis: Brazillian
1
1
Proprietary Nutrient Formulas
1
1
Purple Carrots
1
1
Radish
1
1
Red Wine Extract
1
1
Reseda luteola
1
1
Resins
1
1
Rhodiola (Tibetan Ginseng)
1
1
Rice
1
1
Rice: Black
1
1
Roselle
1
1
SAMe (S-adenosylmethionine)
1
1
Safranal
1
1
Savory
1
1
Schisandra
1
1
Scutellaria barbata
1
1
Sembung Leaf
1
1
Senna
1
1
Sesamol
1
1
Sessile Joyweed
1
1
Smilax glabra
1
1
Solasodine glycoalkaloids
1
1
Soup
1
1
Soybean: Black
1
1
Spearmint
1
1
Spikenard
1
1
Stemona tuberosa
1
1
Sumac
1
1
Tabebuia
1
1
Taxifolin
1
1
Tea Tree
1
1
Terminalia Chebula Gall Extract
1
1
Thymol
1
1
Traditional Chinese Medicine: Xiaotan sanjie recipe
1
1
Tribulus
1
1
Triphala
1
1
Tyrosol
1
1
Vanadium
1
1
Vitex Agnus
1
1
Vitex negundo
1
1
Water: Electrolyzed Reduced
1
1
Watermelon
1
1
Wedelia chinensis
1
1
Wheat Germ
1
1
Wine
1
1
Yellow Sweet Clover (Melilotus officinalis)
1
1
Yellow Tea
1
1
Yerba Mate
1
1
Yoghurt
1
1
Zataria multiflora
1
1
Zinc
1
1
Zyflamend
1
1
Research Articles
3450
Cumulative Knowledge Score
5582
Overall Research Rating
EXCELLENT
View the Evidence:
4570 Abstracts with Antiproliferative Research
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[+]
A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID:
31929811
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
,
Esophageal Cancer
,
Gastric Cancer
,
Liver Cancer
,
Pancreatic Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Berberine exerted anti-tumor effects in a variety of tumors in vivo.
Jun 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cancer. 2019 Jun 17 ;19(1):589. Epub 2019 Jun 17. PMID:
31208348
Article Published Date
: Jun 16, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Berberine
Diseases
:
Breast Cancer
,
Cancers: All
,
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Lycopene inhibits liver cancer cell growth.
Jan 01, 2005
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2005 ;23(3):129-39. PMID:
16410635
Article Published Date
: Jan 01, 2005
Study Type
: Meta Analysis
Additional Links
Substances
:
Lycopene
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
,
Cell cycle arrest
[+]
S. crispa extracts are useful for prevention and treatment of human diseases.
May 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 May 16 ;19(5). Epub 2018 May 16. PMID:
29772715
Article Published Date
: May 15, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Medicinal Mushrooms
Diseases
:
Cancers: All
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antifungal Agents
,
Antioxidants
,
Antiproliferative
[+]
Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.
Oct 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID:
29040973
Article Published Date
: Oct 17, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Sulforaphane
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
A case report of a female patient who demonstrated disease response after declining standard therapy and taking a combination of Laetrile and CBD oil.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gynecol Oncol Rep. 2019 Aug ;29:10-12. Epub 2019 May 17. PMID:
31193514
Article Published Date
: Jul 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Amygdalin (laetrile)
,
Cannabidiol
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Artesunate has anti-proliferative properties in colorectal cancer and is generally well tolerated.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EBioMedicine. 2015 Jan ;2(1):82-90. Epub 2014 Nov 15. PMID:
26137537
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Artemisinin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.
Sep 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID:
26023082
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study, Human Study, In Vitro Study
Additional Links
Substances
:
Cryptoxanthin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Chemotherapeutic Synergy: Oxaliplatin
[+]
Chinese motherwort has cytotoxicity against human breast cancer cells that is non-apoptic and estrogen receptor independent.
Mar 18, 2009
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 Mar 18;122(2):234-9. PMID:
19330917
Article Published Date
: Mar 18, 2009
Study Type
: Human Study
Additional Links
Substances
:
Motherwort
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
[+]
Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Invest Dermatol. 2010 Aug;130(8):2110-9. Epub 2010 Apr 15. PMID:
20393484
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
T-Cell Lymphoma: Cutaneous
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Curcumin suppresses of phosphorylase kinase activity which is correlated to a resolution of psoriasis.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Br J Dermatol. 2000 Nov;143(5):937-49. PMID:
11069500
Article Published Date
: Nov 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Psoriasis
Pharmacological Actions
:
Antiproliferative
,
Dermatologic Agents
,
Enzyme Inhibitors
,
Phosphorylase Kinase Inhibitors
[+]
Danggui can prolong the survival rate of gastric cancer patients in Taiwan.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;48(6):2231-2246. Epub 2018 Aug 16. PMID:
30114701
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Angelica
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
DDW was administered as an oral anticancer agent in addition to conventional therapy, and noticeably prolonged the survival time of all 4 lung cancer patients with brain metastasis.
Aug 31, 2008
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2008 Sep ;7(3):172-81. PMID:
18815148
Article Published Date
: Aug 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Water: Deuterium Depleted
Diseases
:
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-Tumor
,
Antiproliferative
,
Chemopreventive
,
Chemotherapeutic
Additional Keywords
:
Significant Treatment Outcome
[+]
Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2012 Jan ;5(1):41-50. Epub 2011 Dec 1. PMID:
22135048
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
,
Risk Reduction
[+]
Effect of acute exercise on prostate cancer cell growth.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(7):e67579. Epub 2013 Jul 5. PMID:
23861774
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Prostate Cancer
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Physical Activity
,
Risk Reduction
[+]
Evidence of an inhibitory effect of diet and exercise on prostate cancer cell growth.
Aug 31, 2001
Click here to read the entire abstract
Pubmed Data
: J Urol. 2001 Sep ;166(3):1185-9. PMID:
11490320
Article Published Date
: Aug 31, 2001
Study Type
: Human Study
Additional Links
Substances
:
Fiber
Diseases
:
Prostate Cancer
Therapeutic Actions
:
Ai-Chi Aquatic Exercise
,
Dietary Modification: Low Fat Diet
Pharmacological Actions
:
Antiproliferative
[+]
Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.
Mar 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2013 Apr ;16(4):357-60. PMID:
23566060
Article Published Date
: Mar 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Enterolactone
,
Flaxseed
,
Lignans
Diseases
:
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Grape seed procyanidin extract mediates antineoplastic effects against lung cancer.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2016 Dec ;9(12):925-932. Epub 2016 Sep 22. PMID:
27658889
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Proanthocyanidins
[+]
Green tea drinkers with susceptible IGF1 (CA)19/(CA)19 and (CA)19/X genotypes had a significant reduced risk of lung cancer.
Jan 01, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2012 ;7(2):e30951. Epub 2012 Feb 7. PMID:
22347413
Article Published Date
: Jan 01, 2012
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Lung Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Risk Reduction
Problem Substances
:
Tobacco: Smoking
[+]
High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.
Jan 06, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 12 7 ;7(1):17188. Epub 2017 Dec 7. PMID:
29215048
Article Published Date
: Jan 06, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
HLA-DQ2/8 genes may not cause gluten-associated villous atrophy, rather, be activated as a consequence of the pathological process.
Dec 31, 2004
Click here to read the entire abstract
Pubmed Data
: Clin Chem Lab Med. 2005 ;43(7):685-95. PMID:
16207126
Article Published Date
: Dec 31, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
HLA-DQ2/DQ8
,
Questions Of Causality
[+]
Hyperbaric oxygen therapy may be an appropriate therapeutic regimen for the treatment of patients with osteosarcoma.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2009 Nov;22(5):1045-50. PMID:
19787219
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Osteosarcoma
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Drug Synergy
[+]
Metabolised pycnogenol induces apoptosis in human fibrosarcoma cells.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2015 Apr ;46(4):1629-36. Epub 2015 Jan 27. PMID:
25625225
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Fibrosarcoma
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Gene Expression Regulation
,
Natural Substance Synergy
[+]
Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.
Feb 16, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Feb 17. Epub 2015 Feb 17. PMID:
25691730
Article Published Date
: Feb 16, 2015
Study Type
: Human Study
Additional Links
Substances
:
Caffeic Acid
,
Caffeine
Diseases
:
Breast Cancer
,
Breast Cancer: Estrogen
Pharmacological Actions
:
Anti-Tumor
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
,
Estrogen Receptor Modulators
,
Insulin-Like Growth Factor Inhibition/Downregulation
Additional Keywords
:
Dose Response
,
Risk Reduction
Problem Substances
:
Tamoxifen
[+]
Molecular iodine-treated tumors exhibit less invasive potential, and significant increases in apoptosis, estrogen receptor expression, and immune cell infiltration.
Jul 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Jul 17 ;11(7). Epub 2019 Jul 17. PMID:
31319484
Article Published Date
: Jul 16, 2019
Study Type
: Human Study
Additional Links
Substances
:
Iodine
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
,
Immunomodulatory
[+]
N-acetylcysteine compares favorably to metformin on mammographic density in postmenopausal women.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Vopr Onkol. 2012 ;58(1):45-9. PMID:
22629827
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Breast: Mammographic Density
,
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Hypoglycemic Agents
Additional Keywords
:
Drug: Metformin
,
Natural Substances Versus Drugs
[+]
Naringenin from Citrus aurantium inhibits osteosarcoma progression.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:8713263. Epub 2018 Feb 7. PMID:
29576857
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Bitter Orange
,
Naringenin
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Antiproliferative
[+]
Resveratrol reduces tumor cell proliferation in colorectal patients.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Antiviral Res. 2008 Feb;77(2):153-6. Epub 2007 Oct 8. PMID:
20841478
Article Published Date
: Feb 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Stilbenes
[+]
Shikonin could inhibit the growth of lung cancer and improve the immune function of the body and could be a safe and effective treatment.
Sep 30, 1991
Click here to read the entire abstract
Pubmed Data
: Zhong Xi Yi Jie He Za Zhi. 1991 Oct ;11(10):598-9, 580. PMID:
1806305
Article Published Date
: Sep 30, 1991
Study Type
: Human Study
Additional Links
Substances
:
Lithospermum erythrorhizon
,
Shikonin
Diseases
:
Lung Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Antiproliferative
,
Immunomodulatory
[+]
Sinecatechins 10% ointment presents a botanically based alternative to currently available treatments for EGWs that offers a satisfactory balance of clearance rates, reduced frequency of lesion recurrence.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Skin Therapy Lett. 2015 Jan-Feb;20(1):6-8. PMID:
25807215
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Green Tea
Diseases
:
Genital Warts
,
Human Papilloma Virus
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Antiviral Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Supplementation with fish oil for the first 9 weeks of chemotherapy may contribute to delay in tumor progression in colorectal patients.
Dec 22, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Dec 23:1-7. Epub 2015 Dec 23. PMID:
26700096
Article Published Date
: Dec 22, 2015
Study Type
: Human Study
Additional Links
Substances
:
Fish Oil
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Supplementing sorafenib with vitamin K may produce synergistic therapeutic effects against hepatocellular carcinoma.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Hepatobiliary Pancreat Surg. 2015 Feb ;19(1):1-5. Epub 2015 Feb 28. PMID:
26155269
Article Published Date
: Jan 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Vitamin K2
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Chemothapeutic Synergy: Sorafenib
,
Significant Treatment Outcome
[+]
The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Cancer. 2013 ;65(2):240-6. PMID:
23441611
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, Human Study
Additional Links
Substances
:
Water: Deuterium Depleted
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Carcinoma: Small Cell Lung
,
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
Additional Keywords
:
Gene Expression Regulation
,
Proto-oncogene
[+]
These pilot data suggest that a flaxseed-supplemented, fat-restricted diet may affect prostate cancer biology and associated biomarkers.
Jun 30, 2001
Click here to read the entire abstract
Pubmed Data
: Urology. 2001 Jul ;58(1):47-52. PMID:
11445478
Article Published Date
: Jun 30, 2001
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostate Cancer
,
Testosterone: Too High
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID:
22027761
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Tannic Acid
Diseases
:
Cancers
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.
Nov 13, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2012 Nov 14 ;60(45):11372-7. Epub 2012 Nov 6. PMID:
23066935
Article Published Date
: Nov 13, 2012
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginger
Diseases
:
Cancers
,
Carcinoma: Non-Small-Cell Lung
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Biotransformation
,
Plant Extracts
[+]
A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.
Oct 27, 2014
Click here to read the entire abstract
Pubmed Data
: Microvasc Res. 2014 Oct 28 ;97C:167-180. Epub 2014 Oct 28. PMID:
25446010
Article Published Date
: Oct 27, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Black Raspberry
Pharmacological Actions
:
Anti-Angiogenic
,
anti-inflammatory
,
Anti-metastatic
,
Anti-Tumor
,
Anticarcinogenic Agents
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Epigenetic Modification
,
Plant Extracts
[+]
A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.
Mar 29, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID:
24742583
Article Published Date
: Mar 29, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Cancers: Drug Resistant
,
Pancreatic Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Cancer Stem Cells
,
Dietary Concentrations
[+]
A Nigella sativa extract showed a 88.3% inhibition of proliferation of SiHa human cervical cancer cells and increased the expression of caspase-3, -8 and -9 several-fold
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nat Prod Commun. 2013 Feb ;8(2):213-6. PMID:
23513732
Article Published Date
: Jan 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Caspase-9 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Plant Extracts
[+]
An ethanolic extract of T. camphoratus treatment further enhanced the tumor suppression efficiency of cisplatin and doxorubicin.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2015 ;2015:415269. Epub 2015 Oct 18. PMID:
26557666
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Antrodia camphorata
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemosensitizer
,
P21 Activation
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
,
Chemotherapeutic Synergy: Doxorubicin
,
Plant Extracts
[+]
An extract of Amla fruit inhibited human papillomavirus viral oncogenes responsible for development and progression of cervical cancer.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2013 ;65 Suppl 1:88-97. PMID:
23682787
Article Published Date
: Dec 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Amla Fruit
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Antiviral Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Epigenetic Modification
,
Phytotherapy
,
Plant Extracts
[+]
An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(7):e0132439. Epub 2015 Jul 15. PMID:
26176704
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Rosemary
Diseases
:
Melanoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Anandamide is a potent and selective inhibitor of the proliferation of breast cancer cells.
Jul 06, 1998
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8375-80. PMID:
9653194
Article Published Date
: Jul 06, 1998
Study Type
: Human In Vitro
Additional Links
Substances
:
Anandamide
,
Cannabinoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Cannabinoid Receptors
,
Dose Response
[+]
Angelica sinesis extracts display antiproliferative, anti-inflammatory, anti-mutagenic effects in vitro.
Mar 01, 2018
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2018 Mar ;43(6):1235-1240. PMID:
29676134
Article Published Date
: Mar 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Dong Quai
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-cancer
,
Anti-Inflammatory Agents
,
Antimutagenic Agents
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.
Aug 24, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Aug 25. Epub 2016 Aug 25. PMID:
27569589
Article Published Date
: Aug 24, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Prostate Cancer
,
Prostate Cancer Stem Cells
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
Apigenin is a novel therapeutic candidate for melanoma.
Feb 13, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb 14. Epub 2017 Feb 14. PMID:
28260058
Article Published Date
: Feb 13, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Apigenin is a promising chemotherapeutic agent that may be used in the treatment of human osteosarcoma.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Aug ;34(2):1035-41. Epub 2015 May 29. PMID:
26035210
Article Published Date
: Jul 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Antiproliferative
,
Chemotherapeutic
,
Wnt/β-catenin pathway down-regulation
[+]
Arctigenin is able to inhibit cell proliferation and may induce apoptosis and cell cycle arrest at the G0/G1 phase in glioma cells.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Feb ;13(2):1007-1013. Epub 2016 Dec 8. PMID:
28356992
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Arctigenin
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Berberine may serve as a potential therapeutic option for patients with psoriasis.
Mar 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2019 Mar 20 ;10(4):274. Epub 2019 Mar 20. PMID:
30894513
Article Published Date
: Mar 19, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Psoriasis
Pharmacological Actions
:
Antiproliferative
[+]
Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.
Jan 10, 2015
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2015 11-12;29(6):711-728. PMID:
26546528
Article Published Date
: Jan 10, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Lung Cancer
,
Non-Small-Cell Lung Carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Gene Expression Regulation
[+]
Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Photochem Photobiol B. 2015 Jan ;142:197-203. Epub 2014 Dec 12. PMID:
25550119
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Diseases
:
Melanoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Tumor Suppressor Protein p53 Upregulation
[+]
Camel milk inhibited HepG2 and MCF7 cells survival and proliferation.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2012 ;2012:593195. Epub 2012 May 13. PMID:
22654482
Article Published Date
: Dec 31, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Camel Milk
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Cannabidiolic acid an active component in the cannabis plant offers potential therapeutic modality in the abrogation of cancer cell migration.
Nov 14, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Lett. 2012 Nov 15 ;214(3):314-9. Epub 2012 Sep 8. PMID:
22963825
Article Published Date
: Nov 14, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabis
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Chaga mushroom extract can inhibit the proliferation of tumor cells.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Int J Med Mushrooms. 2014 ;16(1):29-36. PMID:
24940902
Article Published Date
: Dec 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
Additional Keywords
:
Plant Extracts
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Cancer Res Clin Oncol. 2015 Sep ;141(9):1511-22. Epub 2014 Dec 28. PMID:
25544670
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Catechin
,
EGCG (Epigallocatechin gallate)
,
Green Tea
Diseases
:
Cancers: All
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Cancer Stem Cells
,
Natural Substance/Drug Synergy
[+]
Cucurmosin has potential anticancer activity for human hepatoma.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2012 Jan ;5(1):196-201. Epub 2011 Sep 30. PMID:
21964700
Article Published Date
: Dec 31, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Pumpkin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Curcumin can suppress the proliferation of keratinocytes with IL-22 or without IL-22 treatment.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015;8(6):9580-9584. Epub 2015 Jun 15. PMID:
26309628
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Psoriasis
Pharmacological Actions
:
Antiproliferative
[+]
Curcumin inhibited proliferation and induced apoptosis in both KG-1 and U937 cells.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Hematol Oncol Stem Cell Res. 2016 Jul 1 ;10(3):120-9. PMID:
27489587
Article Published Date
: Jun 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Acute Myeloid Leukemia
,
Acute Myeloid Leukemia: Stem Cell
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Cancer Stem Cells
[+]
Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015;10(12):e0144462. Epub 2015 Dec 10. PMID:
26656720
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Adiponectin Down-Regulation
,
Anti-metastatic
,
Antiproliferative
[+]
Curcumin reduced Akt expression, cell proliferation, and migration in MDA-MB-231 breast cancer cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(1):e0146553. Epub 2016 Jan 11. PMID:
26752181
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Dose Response
[+]
Curcumin treatment causes a rapid increase in reactive oxygen species and a decrease in the mitochondrial membrane potential-events leading to apoptosis activation.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2014 Dec ;48(12):1397-408. Epub 2014 Oct 6. PMID:
25179440
Article Published Date
: Nov 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Heat Shock Protein Inducer
[+]
Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Radiat Res. 2008 Sep ;170(3):327-34. PMID:
18763855
Article Published Date
: Sep 01, 2008
Study Type
: Human In Vitro
Additional Links
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Apoptotic
[+]
Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Radiat Res. 2008 Sep ;170(3):327-34. PMID:
18763855
Article Published Date
: Sep 01, 2008
Study Type
: Human In Vitro
Additional Links
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Apoptotic
[+]
Electromagnetic fields induce astrocytoma proliferation in vitro.
Jan 12, 2009
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 2009 12 ;24(12):1551-61. PMID:
19795354
Article Published Date
: Jan 12, 2009
Study Type
: Human In Vitro
Additional Links
Diseases
:
Astrocytoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Heat Shock Protein Inducer
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Extracts of T. sinensis inhibited cell proliferation and induced apoptosis in human leukemia HL-60 cells.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem Lett. 2014 Sep 1 ;24(17):4286-90. Epub 2014 Jul 14. PMID:
25074815
Article Published Date
: Aug 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Toona sinensis
Diseases
:
Leukemia
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Extremely low frequency electromagnetic fields promote the differentiation of acute promyelocytic leukemia cells by all-trans retinoic acid.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;46(1):389-400. Epub 2018 Mar 23. PMID:
29590658
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Diseases
:
Leukemias
Pharmacological Actions
:
Antiproliferative
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Proliferative
[+]
Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2016 Oct ;41(10):2728-2751. Epub 2016 Jul 9. PMID:
27394418
Article Published Date
: Sep 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
Gamma- tocopherol was superior to alpha- tocopherol in the inactivation of the Kinase Akt.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Signal. 2013 ;6(267):ra19. Epub 2013 Mar 19. PMID:
23512990
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Vitamin E
,
Vitamin E: Gamma-Tocopherol
Diseases
:
Cancer: Prostate
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Enzyme Inhibitors
Additional Keywords
:
Akt Inhibition
[+]
Gingko Biloba attentuates the genotoxic effects of 1.8 GHz radiofrequency radiation.
Dec 01, 2011
Click here to read the entire abstract
Pubmed Data
: Sci Total Environ. 2011 Dec 1 ;410-411:59-64. Epub 2011 Oct 19. PMID:
22014767
Article Published Date
: Dec 01, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
DNA damage
Pharmacological Actions
:
Antiproliferative
,
Radioprotective
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
Adverse Pharmacological Actions
:
Genotoxic
[+]
Graviola extracts inhibited the proliferation of HL-60 cells in a concentration dependent manner and induced apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2014 ;14(1):516. Epub 2014 Dec 24. PMID:
25539720
Article Published Date
: Dec 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Graviola
Diseases
:
Acute Myeloid Leukemia
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Honokiol has a unique application in chemotherapy for human thyroid cancers.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Jan ;115:288-298. Epub 2016 Dec 7. PMID:
27940017
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Honokiol
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
Horsetail demonstrates significant antioxidant and antiproliferative effects in vitro.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Apr ;13(2):452-9. PMID:
20170379
Article Published Date
: Apr 01, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Horsetail
Diseases
:
Cancers
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Human NB SH-SY5Y cells undergo apoptosis in response to treatment with cucurbitacin B.
Jun 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2014 Jul ;10(1):89-94. Epub 2014 Apr 24. PMID:
24789581
Article Published Date
: Jun 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Inhibition of ERK1/2 signalling pathway is involved in melatonin's antiproliferative effect on human MG-63 osteosarcoma cells.
Nov 06, 2016
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Cell Physiol Biochem. 2016 Nov 7 ;39(6):2297-2307. Epub 2016 Aug 7. PMID:
27832629
Article Published Date
: Nov 06, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Antiproliferative
[+]
Inhibition of oncoprotein cell division cycle 20 by curcumin could be useful for the treatment of pancreatic cancer.
Feb 03, 2017
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Nutrients. 2017 Feb 4 ;9(2). Epub 2017 Feb 4. PMID:
28165402
Article Published Date
: Feb 03, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Isoliquiritigenin is a candidate agent for the treatment of human ovarian cancer.
Sep 20, 2017
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Int J Mol Sci. 2017 Sep 21 ;18(10). Epub 2017 Sep 21. PMID:
28934130
Article Published Date
: Sep 20, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Autophagy Up-regulation
[+]
It is likely that different types of cells and from different species might respond differently to mobile phone radiation.
Sep 01, 2006
Click here to read the entire abstract
Pubmed Data
: Proteomics. 2006 Sep ;6(17):4769-80. PMID:
16878295
Article Published Date
: Sep 01, 2006
Study Type
: Human In Vitro
Additional Links
Pharmacological Actions
:
Antiproliferative
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Lovastatin exhibits toxicity in human fetal brain cells.
Jan 01, 1995
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID:
7708017
Article Published Date
: Jan 01, 1995
Study Type
: Human In Vitro
Additional Links
Diseases
:
Abortion: Spontaneous
,
Birth Defects
,
Neurotoxicity
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Antiproliferative
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Neurotoxic
,
Teratogenic
[+]
Lyophilised camel's milk triggered apoptosis in BT-474 human breast cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Asian Pac J Cancer Prev. 2015 ;16(15):6651-61. PMID:
26434890
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Camel Milk
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
M. nigra may be a novel candidate for the development of new natural product based therapeutic agents against prostate cancer.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Saudi Pharm J. 2017 Feb ;25(2):241-248. Epub 2016 Jun 20. PMID:
28344475
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mulberry
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Mandarin juice exerts in vitro antiproliferative effects on anaplastic thyroid carcinoma cells, associated with a reduction of migration.
Sep 11, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Sep 12:1-8. Epub 2015 Sep 12. PMID:
26365817
Article Published Date
: Sep 11, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Orange: Mandarin
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Melatonin in combination with HDAC inhibitors may be a novel therapeutic intervention for human lung adenocarcinoma.
Jul 15, 2015
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2015 Jul 16. Epub 2015 Jul 16. PMID:
26184924
Article Published Date
: Jul 15, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human liver cancer cells.
Feb 07, 2017
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2017 Feb 8. Epub 2017 Feb 8. PMID:
28178378
Article Published Date
: Feb 07, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: Sorafenib
,
Dose Response
[+]
N-acetyl cysteine blocks the proliferative effects of power frequency magnetic fields in vitro.
Apr 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Int J Mol Sci. 2016 Apr 6 ;17(4):510. Epub 2016 Apr 6. PMID:
27058530
Article Published Date
: Apr 06, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Pharmacological Actions
:
Antiproliferative
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Proliferative
[+]
Nexrutine as an agent to potentiate the therapeutic response of docetaxel by suppressing activation of c-FLIP and its upstream regulators.
May 08, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2017 May 9. Epub 2017 May 9. PMID:
28485511
Article Published Date
: May 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Nexrutine (Phellodendrom)
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
NF-kappaB Inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Docetaxel
[+]
Nigella sativa has successfully produced inhibition of growth of MCF cell lines with an equivalent potency as that of the standard cisplatin.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Pharmacognosy Res. 2015 Apr-Jun;7(2):193-7. PMID:
25829794
Article Published Date
: Mar 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Natural Substances Versus Drugs
,
Superiority of Natural Substances versus Drugs
[+]
Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.
May 08, 2012
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2012 May 8. Epub 2012 May 8. PMID:
22566066
Article Published Date
: May 08, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Catechin
,
EGCG (Epigallocatechin gallate)
,
Ginseng
,
Green Tea
,
Panaxadiol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Natural Substance Synergy
[+]
Parthenolide is a strong apoptotic inducer that deserves the further investigations for potential chemotherapeutic agent of human oral cancers.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oral Oncol. 2015 Jun ;51(6):602-9. Epub 2015 Mar 26. PMID:
25817195
Article Published Date
: May 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Parthenolide
Diseases
:
Oral Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
Pathogenesis and anti-proliferation mechanisms of crocin in human gastric carcinoma cells.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Int J Clin Exp Pathol. 2020 ;13(5):912-922. Epub 2020 May 1. PMID:
32509062
Article Published Date
: Dec 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Crocin
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
,
Nrf2 activation
[+]
Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Jan ;24(1):50-8. Epub 2014 Nov 20. PMID:
25479727
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Piperine
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Probiotic lactobacillus had inhibitory effects of on the growth of human colonic carcinoma cell line HT-29.
Jan 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2017 Jan 10 ;22(1). Epub 2017 Jan 10. PMID:
28075415
Article Published Date
: Jan 09, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Lactobacillus probiotics
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.
Apr 15, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID:
21496306
Article Published Date
: Apr 15, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Fermented Foods and Beverages
,
Wheat Germ
Diseases
:
Cancers
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Chemotherapeutic Synergy: Oxaliplatin
,
Plant Extracts
[+]
Pterostilbene might be used to modulate two anticancer compounds in well-defined sets of GBM patients.
Nov 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Oncotarget. 2016 Nov 8 ;7(45):73200-73215. PMID:
27689322
Article Published Date
: Nov 07, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Pterostilbene
Diseases
:
Glioblastoma Multiforme
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Gefitinib
,
Natural Substance/Drug Synergy
[+]
Red ginseng extract promotes the hair growth in cultured human hair follicles.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2015 Mar ;18(3):354-62. Epub 2014 Nov 14. PMID:
25396716
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Hair Loss
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Hair Regeneration
,
Plant Extracts
[+]
Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.
Dec 14, 2016
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2016 Dec 15. Epub 2016 Dec 15. PMID:
28000876
Article Published Date
: Dec 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
MicroRNA modulator
[+]
Resveratrol may represent a new interesting therapeutic approach, in order to affect glioma stem cell proliferation and motility.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: PLoS One. 2017 ;12(1):e0169854. Epub 2017 Jan 12. PMID:
28081224
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Glioblastoma Multiforme
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Cancer Stem Cells
[+]
Sanguinarine induces apoptosis of human oral squamous cell carcinoma KB cells.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2016 Aug ;77(5):227-40. Epub 2016 Jul 1. PMID:
27363951
Article Published Date
: Jul 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Bloodroot
Diseases
:
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-9 Activation
[+]
Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.
Apr 10, 2017
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2017 Apr 11. Epub 2017 Apr 11. PMID:
28401486
Article Published Date
: Apr 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Shikonin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic Synergy: Temozolomide
,
Glioblastoma
,
Shikonin
[+]
Spirulina platensis and related tetrapyrroles have potent antiproliferative effects on experimental human pancreatic cancer.
Feb 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Hepatol. 2014 Mar-Apr;13(2):273-83. PMID:
24552870
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Spirulina
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antioxidant
,
Antiproliferative
,
Chemopreventive
,
MicroRNA modulator
Additional Keywords
:
Tetrapyrrolic Compounds
[+]
Sulforaphane decreases leukemia cell viability in vitro by inhibiting NADPH oxidase enzymes and redox transporter signaling.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:4125297. Epub 2018 Nov 18. PMID:
30581529
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Leukemia
Pharmacological Actions
:
Antioxidant
,
Antioxidant Effects
,
Antiproliferative
,
NADPH Oxidase Inhibitors
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Isothiocyanates
[+]
Sulforaphane inhibits Wnt/β-catenin signaling in colorectal cancer cells, supressing proliferation and inducing cell death.
Sep 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2018 Sep 21 ;9(74):33982-33994. Epub 2018 Sep 21. PMID:
30338040
Article Published Date
: Sep 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Anti-cancer
[+]
Sulforaphane suppresses proliferation and enhances apoptosis of gastric cancer stem cells in vitro.
Aug 01, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2019 Aug ;70(5):570-578. Epub 2019 Jan 9. PMID:
30624124
Article Published Date
: Aug 01, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Gastric Cancer
,
Gastric Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Anti-cancer
[+]
Sulforaphene inhibits liver cancer cell proliferation by stimulating apoptosis and causing cytotoxicity.
Jun 04, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jun 4 ;10(6). Epub 2018 Jun 4. PMID:
29866995
Article Published Date
: Jun 04, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Tetrahydrocurcumin exhibited significant cell growth inhibition by inducing MCF-7 cells to undergo mitochondrial apoptosis and G2/M arrest.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 May ;67:193-200. Epub 2014 Mar 1. PMID:
24593988
Article Published Date
: Apr 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin: Degradiation byproducts
,
Tetrahydrocurcumin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Caspase-3 Activation
,
Cell cycle arrest
,
P21 Activation
[+]
THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells.
Apr 30, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Invest. 2010 May ;28(4):357-63. PMID:
19916793.
Article Published Date
: Apr 30, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
The apple polyphenol phloretin inhibits colorectal cancer cell growth.
Sep 13, 2016
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2016 Sep 14 ;64(36):6826-37. Epub 2016 Sep 2. PMID:
27538679
Article Published Date
: Sep 13, 2016
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Apple Polyphenols
,
Phloretin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Tumor Suppressor Protein p53 Upregulation
[+]
The present study results indicated that human bladder cancer T-24 cells are highly sensitive to growth inhibition by apigenin.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Cancer Cell Int. 2015 ;15:33. Epub 2015 Mar 29. PMID:
25859163
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Bladder Cancer
,
Bladder Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Cell cycle arrest
,
P21 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Dose Response
[+]
The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.
Mar 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell. 2006 Apr ;9(4):301-12. PMID:
16616335
Article Published Date
: Mar 31, 2006
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Cannabinoids
Diseases
:
Astrocytoma
,
Cancers: All
,
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Altered Protein Expression
,
Gene Expression Regulation
[+]
The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: BMC Complement Altern Med. 2015 ;15:117. Epub 2015 Apr 14. PMID:
25880988
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Oridonin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
MicroRNA modulator
[+]
The synergistic antiproliferative action of combined γ-tocotrienol and sesamin treatment in mouse and human mammary cancer cells was cytostatic, not cytotoxic.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2013 Jan ;84:347-59. Epub 2012 Dec 22. PMID:
23266736
Article Published Date
: Dec 31, 2012
Study Type
: Human In Vitro, In Vitro Study
Additional Links
Substances
:
Sesamin
,
Tocotrienol: Gamma
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Natural Substance Synergy
[+]
These results increase knowledge of the effect of gastrointestinal digestion on the biological effect of honey against colorectal cancer.
Jan 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Antioxidants (Basel). 2020 Jan 10 ;9(1). Epub 2020 Jan 10. PMID:
31936782
Article Published Date
: Jan 09, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Manuka Honey
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
These results provide important new data for ellagic acid in anti-colorectal carcinoma research.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2017 Feb ;50(2):613-621. Epub 2017 Jan 5. PMID:
28101576
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Gene Expression Regulation
[+]
These results suggest that HEABG may be effective in the prevention and treatment of endometriosis in humans.
Jun 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Int J Mol Med. 2013 Jul ;32(1):67-78. Epub 2013 Apr 25. PMID:
23619991
Article Published Date
: Jun 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Endometriosis
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Plant Extracts
[+]
These results support the potential of extracts of M. oleifera leaf in the treatment of human liver and lung cancers.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Oncol Lett. 2015 Sep ;10(3):1597-1604. Epub 2015 Jul 10. PMID:
26622717
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Liver Cancer
,
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Plant Extracts
[+]
This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.
Dec 31, 2010
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Article Publish Status
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Pubmed Data
: BMC Complement Altern Med. 2011 ;11:129. Epub 2011 Dec 15. PMID:
22171782
Article Published Date
: Dec 31, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Frankincense
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Selective Cytotoxicity
[+]
This study demonstrates that sulforaphane targets multiple signaling pathways to suppress ovarian cancer in vitro and in vivo.
Nov 01, 2018
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Pubmed Data
: Int J Mol Med. 2018 Nov ;42(5):2447-2458. Epub 2018 Sep 6. PMID:
30226534
Article Published Date
: Nov 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Female
,
Ovarian Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
HER-2 oncoprotein down-regulation
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Drug Synergy
,
Isothiocyanates
[+]
Thymoquinone promotes pancreatic cancer cell death and reduction of tumor size.
Dec 31, 2015
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Article Publish Status
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Pubmed Data
: Adv Prev Med. 2016 ;2016:1407840. Epub 2016 Dec 26. PMID:
28105374
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Thymoquinone
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Cell cycle arrest
,
Histone deacetylase inhibitor
,
P21 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Dose Response
[+]
Ursolic acid could affect the proliferation and apoptosis of human ovarian cancer stem-like cells and it is a potent anti-ovarian cancer agent.
Oct 31, 2015
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Pubmed Data
: Oncol Rep. 2015 Nov ;34(5):2375-84. Epub 2015 Aug 20. PMID:
26323892
Article Published Date
: Oct 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Ursolic Acid
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Cancer Stem Cells
[+]
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.
Jan 09, 2017
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Article Publish Status
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Pubmed Data
: BMC Complement Altern Med. 2017 Jan 10 ;17(1):36. Epub 2017 Jan 10. PMID:
28073348
Article Published Date
: Jan 09, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Carrot
Diseases
:
Skin Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.
Jan 31, 2014
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Pubmed Data
: Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID:
23761018
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Wogonin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
PI3K/Akt/signaling suppression
Additional Keywords
:
Cancer Glycolysis
,
Resistance Reversal
[+]
Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.
Mar 31, 2017
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Article Publish Status
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Pubmed Data
: Oncol Lett. 2017 Apr ;13(4):2397-2402. Epub 2017 Feb 14. PMID:
28454410
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Zerumbone
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
α-mangostin may be used as food supplement or a potential therapeutic compound for breast cancer.
Feb 17, 2016
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Pubmed Data
: Int J Oncol. 2016 Feb 18. Epub 2016 Feb 18. PMID:
26892433
Article Published Date
: Feb 17, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangosteen
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
γ-tocotrienol and 6-gingerol when used in combination act synergistically increasing cytotoxicity and apoptosis in cancer cells.
Dec 31, 2014
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Article Publish Status
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Pubmed Data
: Molecules. 2015 ;20(6):10280-97. Epub 2015 Jun 3. PMID:
26046324
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Gingerol
,
Tocotrienol: Gamma
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Natural Substance Synergy
[+]
Pepper spray induced conjunctival proliferation, serious enough to require surgical excision, has been reported.
Sep 01, 2011
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Pubmed Data
: Cornea. 2011 Sep ;30(9):1042-4. PMID:
21642850
Article Published Date
: Sep 01, 2011
Study Type
: Human: Case Report
Additional Links
Diseases
:
Conjunctival Diseases
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Pepper Spraying
Problem Substances
:
Pepper Spray
[+]
The data presented here may indicate that CBD led to a partial tumour response in a patient with histologically proven adenocarcinoma of the lung.
Dec 31, 2018
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Article Publish Status
: This is a free article.
