Antispasmodic

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35 Substances Researched for Antispasmodic
NameACCKFocus
Peppermint330Locked
Valerian424Locked
Cannabidiol110Locked
Coriandrum sativum110Locked
Delta-tetrahydrocannabinol (THC)110Locked
Homeopathic Medicine: All110Locked
Melissa (Lemonbalm)110Locked
Mentha spicata110Locked
Psyllium110Locked
Threonine110Locked
Magnesium26Locked
Black Pepper24Locked
Curcumin24Locked
Rooibos24Locked
Anise12Locked
Apigenin12Locked
Black Currant12Locked
Cannabinoids 12Locked
Cannabis12Locked
Catnip12Locked
Mulberry12Locked
Myrica sapida12Locked
Noni12Locked
Parsley12Locked
Purslane12Locked
Quercetin12Locked
Resveratrol12Locked
Thyme22Locked
Chamomile11Locked
Charcoal 11Locked
Ginger11Locked
Mugwort11Locked
Myrrh11Locked
Nigella sativa (aka Black Seed)11Locked
Yarrow10Locked

View the Evidence:
38 Abstracts with Antispasmodic Research

[+]

" Valerian seems to be an effective treatment for dysmenorrhea, probably because of its antispasmodic effects."Sep 27, 2011

Pubmed Data : Int J Gynaecol Obstet. 2011 Sep 27. Epub 2011 Sep 27. PMID: 21959068
Article Published Date : Sep 27, 2011
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Dysmenorrhea, Menstrual Cramps
Pharmacological Actions : Antispasmodic
[+]

A combination of Melissa (Lemonbalm), Mentha spicata, Coriandrum sativum, Psyllium appears to have therapeutic value in treating IBS. Aug 01, 2006

Pubmed Data : Dig Dis Sci. 2006 Aug;51(8):1501-7. Epub 2006 Jul 26. PMID: 16868824
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Substances : Coriandrum sativum, Melissa (Lemonbalm), Mentha spicata, Psyllium
Diseases : Bloating, Irritable Bowel Syndrome
Pharmacological Actions : Antispasmodic, Carminative, Hypnotics and Sedatives
[+]

Delta-tetrahydrocannabinol (THC) and cannabidiol have therapeutic value in the management of spasticity associated wtih multiple sclerosis. Aug 01, 1996

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 1996 Aug;42(4):325-37. PMID: 21456949
Article Published Date : Aug 01, 1996
Study Type : Human Study
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Multiple Sclerosis, Muscle Spasticity
Pharmacological Actions : Antispasmodic
[+]

Peppermint has anti-spasm properties during colonscopy. Aug 31, 2012

Pubmed Data : Acta Gastroenterol Belg. 2012 Sep ;75(3):349-53. PMID: 23082707
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Peppermint
Diseases : Colonic Spasm
Pharmacological Actions : Antispasmodic
[+]

Peppermint oil is a safe and effective alternative for the elimination of colonic spasms instead of Buscopan during a double-contrast barium enema.Apr 01, 2003

Pubmed Data : Clin Radiol. 2003 Apr;58(4):301-5. PMID: 12662951
Article Published Date : Apr 01, 2003
Study Type : Human Study
Additional Links
Substances : Peppermint
Diseases : Colonic Spasm
Pharmacological Actions : Antispasmodic
[+]

Peppermint oil is useful as an antispasmodic agent for endoscopic retrograde cholangiopancreatography.Sep 01, 2006

Pubmed Data : J Gastroenterol Hepatol. 2006 Sep;21(9):1394-8. PMID: 16911682
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Substances : Peppermint
Diseases : Endoscopic Surgical Procedures
Pharmacological Actions : Antispasmodic
[+]

Spascupreel seems to be an effective and well tolerated alternative to conventional therapies in children suffering from gastrointestinal spasms.May 31, 2007

Pubmed Data : Pediatr Int. 2007 Jun ;49(3):328-34. PMID: 17532830
Article Published Date : May 31, 2007
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Abdominal Cramps, Gastric Spasm
Pharmacological Actions : Antispasmodic
Additional Keywords : Homeopathic Vs. Conventional Treatment, Phytotherapy, Plant Extracts
[+]

Threonine may reduce signs of spasticity in multiple sclerosis.Sep 01, 1992

Pubmed Data : Arch Neurol. 1992 Sep;49(9):923-6. PMID: 1520082
Article Published Date : Sep 01, 1992
Study Type : Human Study
Additional Links
Substances : Threonine
Diseases : Multiple Sclerosis
Pharmacological Actions : Antispasmodic
[+]

Valerian extract inhibits contractility of the human uterus justifying its traditional use in the treatment of uterine cramping associated with dysmenorrhoea. Feb 01, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Feb;61(2):251-6. PMID: 19178774
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Dysmenorrhea, Uterine Cramps
Pharmacological Actions : Antispasmodic
[+]

Case report: painful muscle spasm has been reversed by magnesium sulphate. Aug 31, 1985

Pubmed Data : S Afr Med J. 1985 Aug 31;68(5):332-3. PMID: 4035497
Article Published Date : Aug 31, 1985
Study Type : Human: Case Report
Additional Links
Substances : Magnesium
Diseases : Muscle Spasm
Pharmacological Actions : Antispasmodic
[+]

Magnesium may reduce spasticity Multiple Sclerosis.Nov 01, 2000

Pubmed Data : Eur J Neurol. 2000 Nov;7(6):741-4. PMID: 11136367
Article Published Date : Nov 01, 2000
Study Type : Human: Case Report
Additional Links
Substances : Magnesium
Diseases : Multiple Sclerosis
Pharmacological Actions : Antispasmodic
[+]

An extract of P. oleracea leaves ameliorated the immunosuppressive action of cyclophosphamide in mice.Apr 05, 2018

Pubmed Data : J Ethnopharmacol. 2018 Apr 6 ;215:191-198. Epub 2018 Jan 9. PMID: 29325915
Article Published Date : Apr 05, 2018
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Antispasmodic, Immunomodulatory
Problem Substances : Cyclophosphamide
[+]

Anise demonstrates antispasmodic properties consistent with its use in folk medicine. Jul 01, 2001

Pubmed Data : J Clin Gastroenterol. 2001 Jul;33(1):27-31. PMID: 17027208
Article Published Date : Jul 01, 2001
Study Type : Animal Study
Additional Links
Substances : Anise
Diseases : Gastric Spasm, Muscle Spasm
Pharmacological Actions : Antispasmodic
Additional Keywords : Science Confirms Tradition
[+]

Antispasmodic activity of prenylated phenolic compounds from the root bark of Morus nigra.Jul 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Jul 8 ;24(13). Epub 2019 Jul 8. PMID: 31288489
Article Published Date : Jul 07, 2019
Study Type : Animal Study
Additional Links
Substances : Mulberry
Diseases : Asthma
Pharmacological Actions : Antispasmodic
Additional Keywords : Plant Extracts
[+]

Apigenin and quercetin may have a therapeutic role in preventing and treating gastric spasm. Jul 03, 2009

Pubmed Data : Life Sci. 2009 Jul 3;85(1-2):85-90. Epub 2009 May 8. PMID: 19427869
Article Published Date : Jul 03, 2009
Study Type : Animal Study
Additional Links
Substances : Apigenin, Quercetin
Diseases : Gastric Spasm
Pharmacological Actions : Antispasmodic, Calcium Channel Blockers
[+]

Black pepper has antispasmodic properties.Jun 01, 2008

Pubmed Data : Pak J Biol Sci. 2008 Jun 1;11(11):1492-6. PMID: 18817253
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic
Additional Keywords : Plant Extracts
[+]

Black pepper may have a therapeutic role in the treatment of gastrointestinal disorders.Dec 01, 2009

Pubmed Data : Anticancer Res. 2009 Dec;29(12):4981-8. PMID: 20828313
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic
[+]

Cannabinoids control spasticity and tremor in a multiple sclerosis model.Mar 02, 2000

Pubmed Data : Nature. 2000 Mar 2;404(6773):84-7. PMID: 10716447
Article Published Date : Mar 02, 2000
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Multiple Sclerosis, Muscle Spasticity, Tremor
Pharmacological Actions : Antispasmodic
[+]

Catnip has spasmolytic and bronchodilatory properties, confirming its traditional use in colic, diarrhea, cough and asthma. Jan 03, 2011

Pubmed Data : Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID: 19041706
Article Published Date : Jan 03, 2011
Study Type : Animal Study
Additional Links
Substances : Catnip
Diseases : Bronchial Asthma, Colic, Cough, Diarrhea
Pharmacological Actions : Antispasmodic, Bronchodilator Agents
Additional Keywords : Plant Extracts, Science Confirms Tradition
[+]

Curcuminoids exhibit anti-spasmodic activity in pig ileum and rat uterus. Jan 01, 2007

Pubmed Data : CNS Drugs. 2007;21 Suppl 1:39-43; discussion 45-6. PMID: 12930003
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Uterine Cramps
Pharmacological Actions : Antispasmodic
[+]

Myrica sapida posesses bronchodilator activity, is an antihistamine and reduces the effect of inflammatory mediators on the bronchus. Apr 01, 2008

Pubmed Data : Pharmazie. 2008 Apr;63(4):312-6. PMID: 18468393
Article Published Date : Apr 01, 2008
Study Type : Animal Study
Additional Links
Substances : Myrica sapida
Diseases : Bronchial Asthma, Bronchospasm: Acute
Pharmacological Actions : Antispasmodic, Bronchodilator Agents, Histamine Antagonists
[+]

Noni has antispamodic and vasodilator effects.Jan 13, 2010

Pubmed Data : BMC Complement Altern Med. 2010 Jan 13;10(1):2. Epub 2010 Jan 13. PMID: 20070879
Article Published Date : Jan 13, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cardiovascular Diseases, Hypertension
Pharmacological Actions : Antispasmodic, Calcium Channel Blockers, Vasodilator Agents
[+]

Parsley is spasmolytic effect on rat's ileum, substantiatnig its use in traditional medicine for the treatment of intestinal disorders. Nov 15, 2007

Pubmed Data : Pak J Biol Sci. 2007 Nov 15;10(22):4036-42. PMID: 19090276
Article Published Date : Nov 15, 2007
Study Type : Animal Study
Additional Links
Substances : Parsley
Diseases : Gastric Spasm
Pharmacological Actions : Antispasmodic
[+]

Resveratrol may be an effective therapy for uterine contractions associated with dysmenorrhea. Nov 01, 1993

Pubmed Data : Mutat Res. 1993 Nov;303(3):109-12. PMID: 21363935
Article Published Date : Nov 01, 1993
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Dysmenorrhea, Uterine Contractions: Pain, Uterine Cramps
Pharmacological Actions : Antispasmodic
[+]

Rooibos tea has antispasmodic properties which may be of value in the treatment of hyperactive gastrointestinal disorders. Nov 01, 2006

Pubmed Data : Basic Clin Pharmacol Toxicol. 2006 Nov;99(5):365-73. PMID: 17076689
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Colonic Spasm, Gastric Spasm
Pharmacological Actions : Antispasmodic
[+]

Rooibos tea may have therapeutic potential in treating congestive respiratory ailments due to its bronchodilator, antispasmodic and blood pressure lowering effects. Dec 01, 2006

Pubmed Data : Eur J Nutr. 2006 Dec;45(8):463-9. Epub 2006 Nov 1. PMID: 17080260
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bronchospasm: Acute, Chronic Obstructive Pulmonary Disease, COPD, Respiratory Diseases
Pharmacological Actions : Antispasmodic, Bronchodilator Agents, Hypotensive
[+]

The antispasmodic effect of Ometa cultivar shows that common gastrointestinal disorders could be treated by the functional food.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Princ Pract. 2018 ;27(2):179-185. Epub 2018 Jan 28. PMID: 29402838
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic, Gastrointestinal Agents
[+]

Turmeric has antispasmodic properties. Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(9):e44650. Epub 2012 Sep 12. PMID: 22984538
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Colonic Spasm, Intestinal Spasm
Pharmacological Actions : Antispasmodic, Myorelaxant
[+]

Valerian contains compounds with antispasmodic effects on stimulated smooth muscle cells without activating the autonomic nervous system. Jun 18, 2008

Pubmed Data : Cancer Lett. 2008 Jun 18;264(2):218-28. Epub 2008 Mar 7. PMID: 7114974
Article Published Date : Jun 18, 2008
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Muscle Spasm, Muscle Spasticity
Pharmacological Actions : Antispasmodic
[+]

Valerian root has antibronchospastic, antihypertensive and anticoronaryspastic properties. Jun 13, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jun 13;112(2):361-7. Epub 2007 Mar 20. PMID: 17467210
Article Published Date : Jun 13, 2007
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Bronchospasm: Acute, Coronary Artery Spasm
Pharmacological Actions : Antispasmodic, Bronchoconstrictor Agents, Hypotensive
Additional Keywords : Drug: Nifedipine, Natural Substances Versus Drugs
[+]

Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds.Apr 27, 2022

Pubmed Data : J Ethnopharmacol. 2022 Apr 28 ;295:115314. Epub 2022 Apr 28. PMID: 35490899
Article Published Date : Apr 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Watermelon
Diseases : Asthma, Diarrhea
Pharmacological Actions : Antispasmodic
[+]

Black cumin contains a nigellone and thymoquinone which block leukotriene D4 which is associated with respiratory disease. Feb 01, 2008

Pubmed Data : Planta Med. 2008 Feb;74(2):105-8. Epub 2008 Jan 24. PMID: 18219598
Article Published Date : Feb 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Respiratory Diseases
Pharmacological Actions : Antispasmodic, Leukotriene D4 antagonist
[+]

Ginger is useful in gastrointestinal disorders due to its spasmolytic activity.Oct 01, 2005

Pubmed Data : Dig Dis Sci. 2005 Oct;50(10):1889-97. PMID: 16187193
Article Published Date : Oct 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Ginger
Diseases : Colic, Diarrhea, Dyspepsia
Pharmacological Actions : Antispasmodic
[+]

Mechanisms of spasmolytic and anti-inflammatory effects of a herbal medicinal product consisting of myrrh, chamomile flower, and coffee charcoal.May 01, 2017

Pubmed Data : Wien Med Wochenschr. 2017 May ;167(7-8):169-176. Epub 2017 Jan 13. PMID: 28091973
Article Published Date : May 01, 2017
Study Type : Review
Additional Links
Substances : Chamomile, Charcoal , Myrrh
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antispasmodic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Significance of common mugwort in the history of medicine and its possible contemporary applications.Sep 24, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Sep 25 ;25(19). Epub 2020 Sep 25. PMID: 32992959
Article Published Date : Sep 24, 2020
Study Type : Review
Additional Links
Substances : Mugwort
Diseases : Bacterial Infections, Fungal Infection, Hyperlipidemia, Oxidative Stress
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents, Antioxidants, Antispasmodic, Hepatoprotective, Hypolipidemic
[+]

Thyme extract may help in diseases related to endothelin hyper-reagibility of the bronchus system such as asthma and COPD. Jan 01, 2000

Pubmed Data : Zentralbl Gynakol. 2000;122(11):561-5. PMID: 18729040
Article Published Date : Jan 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Thyme
Diseases : Asthma, Chronic Obstructive Pulmonary Disease
Pharmacological Actions : Antispasmodic
Additional Keywords : The Whole is Superior to the Monochemical Part
[+]

Thymol, an oil found within thyme, is spasmolytic, an alpha and beta adrenergic agonist, and thermogenic. Jan 01, 2007

Pubmed Data : Phytomedicine. 2007 Jan;14(1):65-9. Epub 2006 Dec 20. PMID: 17187972
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Thyme
Diseases : Muscle Spasm
Pharmacological Actions : Adrenergic Agonists, Adrenergic alpha-Agonists, Adrenergic beta-Agonists, Antispasmodic, Thermogenic
[+]

Yarrow's traditional use for gastrointestinal disorders are confirmed by recent findings.Jan 01, 2007

Pubmed Data : Wien Med Wochenschr. 2007;157(13-14):312-4. PMID: 17704978
Article Published Date : Jan 01, 2007
Additional Links
Substances : Yarrow
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic

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