Antiviral Agents

Name	AC	CK
Curcumin	49	72
Elderberry	9	55
Green Tea	8	37
Vitamin D	8	36
Echinacea	5	33
Pelargonium sidoides	4	32
Licorice	17	30
EGCG (Epigallocatechin gallate)	18	27
Vitamin C	11	26
Bee Propolis	5	25
Zinc	6	24
Catechin	4	22
Papaya	3	22
Fucoidan	9	20
Ginseng (American)	2	20
Phyllanthus urinaria	11	20
Garlic	9	19
Dandelion	5	18
Spirulina	6	17
Polyphenols	6	16
Beta-glucan	3	13
Cinnamon	3	13
Isoflavones	3	13
Vitamin C: Intravenous	2	13
Rhodiola (Tibetan Ginseng)	3	12
Silymarin	3	12
Artichoke	2	11
Coffee	2	11
Fermented Foods and Beverages	2	11
Homeopathic Medicine: All	2	11
NAC (N-acetyl-L-cysteine)	8	11
Pine Cone	2	11
Resveratrol	11	11
Woad	2	11
Apricot Kernel	1	10
Bitter Melon	1	10
Camel Milk	1	10
Chinese Herbal Formula: Jinye Baidu	1	10
Chinese Herbal Formula: Shuang Huang Lian Wan	1	10
Chinese Skullcap	8	10
Chlorella (Algae)	1	10
Cocoa	1	10
Ephedra sinica (Ma Huang)	1	10
Ginger	5	10
Kanuka Honey	1	10
Lactobacillus delbrueckii Subsp	1	10
Lemon Myrtle	1	10
Lignans	1	10
Magnesium	1	10
Melissa (Lemonbalm)	1	10
Milk Thistle	1	10
Paris polyphylla	1	10
Propolis: Bee	1	10
Shallot	1	10
Silibinin	1	10
Soy Protein	1	10
Testosterone	1	10
Yeast	1	10
Berberine	7	9
Lactoferrin	7	9
Flavonoids	7	7
Genistein	6	7
Geum japonicum	4	7
Ginsenosides	5	7
Lactobacillus plantarum	4	7
Nigella sativa (aka Black Seed)	4	7
Artemisinin	4	6
Clove	3	6
Probiotics	3	6
Amla Fruit	1	5
Astragalus	3	5
Black Tea	5	5
Blueberry	4	5
Carrageenans	3	5
Chaga Mushroom (Inonotus obliquus)	4	5
Lactobacillus probiotics	3	5
Naringenin	1	5
Neem	5	5
Pomegranate	5	5
Quercetin	3	5
Seaweed	5	5
St. Johns Wort	4	5
AHCC	2	4
Aloe Vera	4	4
Black Currant	3	4
Chlorogenic Acid	4	4
Cranberry	3	4
Emodin	3	4
Ginseng (Korean)	3	4
Glycyrrhizin	4	4
Mangiferin	4	4
Melia azedarach	2	4
Nettle	3	4
Onion	3	4
Prunella vulgaris	3	4
Rhubarb	3	4
Rock-rose	3	4
Schisandra	3	4
Sulforaphane	3	4
Terminalia	2	4
Theaflavins	4	4
Vitamin A	3	4
Xanthohumol	3	4
Banaba	3	3
Betulinic acid	2	3
Bilberry	2	3
Black Raspberry Seed	2	3
Burdock	2	3
Cannabis	2	3
Chrysin	2	3
Ellagic Acid	3	3
Gallic Acid	2	3
Holy Basil	3	3
Houttuynia cordata	2	3
Isoliquiritigenin	2	3
Lemon Balm	3	3
Lysine	3	3
Maitake Mushroom	2	3
Melatonin	2	3
Noni	3	3
Oleuropein	3	3
Punicalagin	3	3
Pycnogenol (Pine Bark)	2	3
Reishi Mushroom	3	3
Rosemary	3	3
Sage	3	3
Tannic Acid	3	3
Thymoquinone	2	3
Turmeric	3	3
Ursolic Acid	3	3
Wormwood	2	3
Zataria multiflora	2	3
Almond	2	2
Apigenin	2	2
Arctigenin	1	2
Bamboo	2	2
Bee Venom	1	2
Bifidobacterium Longum	1	2
Boswellia	2	2
Bran	1	2
Caffeic Acid	2	2
Celastrol	1	2
Cineole	1	2
Clinacanthus siamensis	1	2
Coconut	1	2
Coconut Husk/Fiber	1	2
Cordyceps sinensis	1	2
Delphinidin	2	2
Eugenol	1	2
Feverfew	2	2
Fig	2	2
Fulvic Acid	2	2
Gardenia	1	2
Ginkgo biloba	1	2
Ginseng	1	2
Grape Seed Extract	2	2
Guava	2	2
Hesperidin	2	2
Hibiscus sabdariffa	2	2
Honokiol	2	2
Hops	2	2
Horse Chestnut	1	2
Isomangiferin	2	2
Isoquercitrin	1	2
Japanese Herbal Formula: Sho-seiryu-to	1	2
Kaempferol	2	2
Kimchi	1	2
Lotus	2	2
Mushrooms: All	2	2
Nobiletin	2	2
Oleanolic acid	2	2
Olive leaf extract	2	2
Panax Ginseng	1	2
Peppermint	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Pine Bark Extract	2	2
Plantago	2	2
Psychedelics:All	2	2
Radix Isatidis	2	2
Red Marine Algae	1	2
Rhus javanica	1	2
Rice Bran	1	2
Rosmarinic acid	2	2
Sophora Flavescens	2	2
Soy	2	2
Sumac	1	2
Syrian rue	2	2
Toona sinensis	2	2
Verbascoside	2	2
White Mulberry	2	2
Wogonin	2	2
Yoghurt	1	2
7-epi-nemorosone	1	1
Acacia arabica	1	1
Achillea fragrantissima	1	1
Acorus calamus	1	1
Adlay	1	1
Agrimony	1	1
Andrographis	1	1
Anthocyanins	1	1
Antrodia camphorata	1	1
Antrodia cinnamomea	1	1
Apple Pectin	1	1
Arginine	1	1
Asafoetida	1	1
Asiatic Acid	1	1
Avocado	1	1
Baicalein	1	1
Banana	1	1
Basil	1	1
Basil: Sweet	1	1
Bay leaf	1	1
Berries: All	1	1
Bisdemethoxycurcumin	1	1
Blackberry	1	1
Blue-Green Algae	1	1
Breast Milk	1	1
Bromelain	1	1
Butyrate	1	1
Byrsonima verbascifolia	1	1
Cannabidiol	1	1
Capsaicin	1	1
Carvacrol	1	1
Cat's Claw	1	1
Cayenne	1	1
Cherry: All Varieties	1	1
Chili pepper	1	1
Chrysanthemum Morifolium	1	1
Citrus Pectin	1	1
Clausena excavata	1	1
Coleus Forskohlii	1	1
Curcuminoids	1	1
DHEA (Dehydroepiandrosterone)	1	1
Date Seeds	1	1
Demethoxycurcumin	1	1
Diosgenin	1	1
Eleutherococcus senticosus	1	1
Eugenia dysenterica	1	1
Euphorbia peplus	1	1
Euphorbium resinifera	1	1
False Black Pepper	1	1
Ferulic acid	1	1
Fisetin	1	1
Flaxseed	1	1
Frankincense	1	1
Fructus Ligustri	1	1
Ganoderic acid B	1	1
Garcinia Mangostana	1	1
Garcinia hanburyi	1	1
Gingerol	1	1
Ginseng (Siberian)	1	1
Globularia arabica	1	1
Glutathione	1	1
Glycyrrhiza uralensis	1	1
Grapefruit	1	1
Grapefruit Seed Extract	1	1
Graviola	1	1
Guduchi	1	1
Gum arabic	1	1
Gynostemma	1	1
Heal-All	1	1
Hibiscus	1	1
Hu Zhang (Polygonum cuspidatum)	1	1
Humic Acid	1	1
Hydroxytyrosol	1	1
Hymenaea courbaril	1	1
Hyssop	1	1
Indole-3-Carbinol	1	1
Japanese cypress	1	1
Jasonia montana	1	1
Kaempferia parviflora	1	1
Kudzu	1	1
Lactobacilius bulgaricus	1	1
Lactobacillus casei	1	1
Lamium album	1	1
Lemon Juice	1	1
Lichens	1	1
Lingonberry	1	1
Loquat	1	1
Luchu Pine	1	1
Luteolin	1	1
Lychee	1	1
Mango	1	1
Marigold	1	1
Mikania micrantha	1	1
Milk	1	1
Monolaurin	1	1
Moringa oleifera	1	1
Mosla scabra	1	1
Mullein	1	1
Mung Bean	1	1
Myracrodruon urundeuva	1	1
Myrica rubra	1	1
Myricetin	1	1
Myrrh	1	1
Nordihydroguaiaretic acid (NDGA)	1	1
OPC (Oligomeric Proanthocyanidins)	1	1
Oak	1	1
Oat Bran	1	1
Oligosaccharides	1	1
Olive	1	1
Palmitoylethanolamide	1	1
Papain	1	1
Parthenolide	1	1
Pau D'Arco	1	1
Peanut	1	1
Phellinus Linteus	1	1
Phloretin	1	1
Phyllanthus amarus	1	1
Plant Sterols/Stanols	1	1
Plantago asiatica	1	1
Plukenetione A	1	1
Plum	1	1
Polygonum multiflorum	1	1
Pomegranate Peel	1	1
Potato	1	1
Prickly Pear Cactus	1	1
Proanthocyanidins	1	1
Proprietary Nutrient Formulas	1	1
Pulsatilla pratensis	1	1
Purslane	1	1
Quassia	1	1
Quinic acid	1	1
Raoulia australis	1	1
Raspberry	1	1
Rhizoma cibotte	1	1
Rooibos	1	1
Rosemary: Essential Oil	1	1
Rubia Cordifolia	1	1
Rutin	1	1
Sappanwood	1	1
Sarsaparilla	1	1
Satsuma	1	1
Saxifraga melanocentra	1	1
Sea buckthorn	1	1
Seaweed: Brown	1	1
Silver (nanoparticles)	1	1
Solasodine glycoalkaloids	1	1
Stilbenes	1	1
Strawberry	1	1
Sweet Acacia	1	1
Tabebuia	1	1
Tamanu	1	1
Tangeretin	1	1
Tansy	1	1
Tarragon	1	1
Tetrahydrocurcumin	1	1
Thyme	1	1
Thymol	1	1
Tomatidine	1	1
Trigonostema xyphophylloides	1	1
Tripterygium wilfordii	1	1
Tuberaria	1	1
Ume (Japanese apricot)	1	1
Vatica astrotricha	1	1
Wild Quinine	1	1
Wrightia tinctoria	1	1

[+]

2014 Cochrane: a dose-response effect on psychiatric events. In trials of prevention in adults one person was harmed for every 94 treated. Apr 09, 2014

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Pubmed Data : Cochrane Database Syst Rev. 2014 Apr 10(4):CD008965. Epub 2014 Apr 10. PMID: 24718923

Article Published Date : Apr 09, 2014

Study Type : Meta Analysis

Additional Links

Pharmacological Actions : Antiviral Agents, Enzyme Inhibitors

Additional Keywords : Randomized Controlled Trials As Topic

Problem Substances : Oseltamivir (trade name Tamiflu)

[+]

C. papaya leaf extract can be considered as a potential candidate for increase in platelet count in patients of dengue.Sep 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Appl Basic Med Res. 2016 Oct-Dec;6(4):249-254. PMID: 27857891

Article Published Date : Sep 30, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Papaya

Diseases : Dengue

Pharmacological Actions : Antiviral Agents

[+]

Carica papaya extract in dengue: a systematic review and meta-analysis.Oct 10, 2019

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Pubmed Data : Turk J Pediatr. 2020 ;62(4):634-640. PMID: 32779416

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Bee Products, Bee Propolis, Honey, Royal Jelly

Diseases : Upper Respiratory Infections

Pharmacological Actions : Anti-Bacterial Agents, Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

A Chinese herbal formula containing Paris polyphylla, Dandelion, Woad, and Licorice appears safe and effective in reducing cytomegalovirus infection activity in pregnant women. Apr 01, 2000

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Pubmed Data : Altern Ther Health Med. 2017 Oct 21. Epub 2017 Oct 21. PMID: 29055287

Article Published Date : Oct 20, 2017

Study Type : Human Study

Additional Links

Substances : Pelargonium sidoides

Diseases : Cold: Common

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts, Risk Reduction

[+]

Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection.Nov 30, 2016

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Chinese medicine has potential benefits for patients with severe acute respiratory syndrome (SARS) or SARS-like infections.Jul 01, 2006

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Pubmed Data : J Altern Complement Med. 2006 Jul-Aug;12(6):505-6. PMID: 16884338

Article Published Date : Jul 01, 2006

[+]

Lactoferrin is a potential useful adjunct treatment for patients with chronic hepatitis C.Oct 31, 2007

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Pubmed Data : J Gastroenterol Hepatol. 2007 Nov ;22(11):1894-7. PMID: 17914966

Article Published Date : Oct 31, 2007

Study Type : Human Study

Additional Links

Substances : Lactoferrin

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

[+]

Lactoferrin is one potential candidate as an anti‐HCV reagent that may be effective for the treatment of patients with chronic hepatitis.Mar 31, 1999

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Pubmed Data : Hepatology. 2009 Nov;50(5):1360-9. PMID: 19676128

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

Additional Keywords : Risk Reduction

[+]

Rhodiola rosea may exert protective effects against virus replication following intense and prolonged exercise by inducing antiviral activity.Dec 31, 2014

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Pubmed Data : BMC Psychiatry. 2016 Nov 15 ;16(1):398. Epub 2016 Nov 15. PMID: 27842532

Article Published Date : Nov 14, 2016

Study Type : Human Study

Additional Links

Substances : Silymarin

Diseases : Anxiety Disorders, Depression, Hepatitis C

Pharmacological Actions : Antioxidants, Antiviral Agents

Additional Keywords : Antioxidants, Antiviral Agents, Anxiety Disorders, depression, hepatitis C, SILYMARIN

[+]

Sinecatechins 10% ointment presents a botanically based alternative to currently available treatments for EGWs that offers a satisfactory balance of clearance rates, reduced frequency of lesion recurrence.Dec 31, 2014

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Pubmed Data : Skin Therapy Lett. 2015 Jan-Feb;20(1):6-8. PMID: 25807215

Pubmed Data : J Infect Chemother. 2012 Aug ;18(4):534-43. Epub 2012 Feb 16. PMID: 22350323

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Pubmed Data : Ann Emerg Med. 2009 Jun;53(6):792-5. Epub 2008 Nov 22. PMID: 19028409

Article Published Date : Jun 01, 2009

Study Type : Human Study

Additional Links

Diseases : Chickenpox, Herpes Zoster, Meningitis: Viral

Pharmacological Actions : Antiviral Agents

Additional Keywords : Undefined

Anti Therapeutic Actions : Vaccination: All, Vaccination: Varicella (Chicken pox)

[+]

Vitamin D concentrations of 38 ng/ml or more in healthy adults are associated with a significant two-fold reduction in the risk of developing acute viral respiratory tract infection.Jan 01, 2010

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Pubmed Data : PLoS One. 2010;5(6):e11088. Epub 2010 Jun 14. PMID: 20559424

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Pubmed Data : Food Funct. 2016 Jun 14. Epub 2016 Jun 14. PMID: 27296047

Article Published Date : Jun 13, 2016

Study Type : Human Study

Additional Links

Substances : Artichoke

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

[+]

Zinc and the Chinese herbal formula Jinye Baidu granule significantly increase the negative conversion rate of HCMV-IgM.May 01, 2005

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Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 May;25(5):449-51. PMID: 15957842

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Pubmed Data : Biochem Cell Biol. 2020 Apr 29. Epub 2020 Apr 29. PMID: 32348689

Article Published Date : Apr 28, 2020

Study Type : Human In Vitro

Additional Links

Substances : Lactoferrin

Diseases : Norovirus

Pharmacological Actions : Antiviral Agents

[+]

Black seed, sweet orange, and Anthemis hyalina extracts all exhibit antiviral activity against coronavirus.Mar 01, 2014

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Pubmed Data : Mol Biol Rep. 2014 Mar ;41(3):1703-11. Epub 2014 Jan 12. PMID: 24413991

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Pubmed Data : Nutr Res Pract. 2015 Apr ;9(2):117-22. Epub 2015 Mar 6. PMID: 25861416

Article Published Date : Mar 31, 2015

Study Type : Human In Vitro, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cholera, Gastrointestinal Infections, Inflammation

Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Antiviral Agents, NF-kappaB Inhibitor

[+]

Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines.Oct 31, 2012

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Pubmed Data : J Ethnopharmacol. 2012 Nov 1. Epub 2012 Nov 1. PMID: 23123794

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Pubmed Data : Mol Med Rep. 2014 Apr ;9(4):1381-7. Epub 2014 Jan 29. PMID: 24481875

Article Published Date : Mar 31, 2014

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Dandelion

Diseases : Hepatitis B

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

[+]

A case report of a patient with Chikungunya fever responding swiftly and positively to intravenous vitamin C therapy. Dec 31, 2013

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Pubmed Data : J Orthomol Med. 2014;29(4):154-156. PMID: 25705076

Article Published Date : Dec 31, 2013

Study Type : Human: Case Report

Additional Links

Substances : Vitamin C: Intravenous

Diseases : Chikungunya Virus, Viral Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiviral Agents

[+]

Case report: failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man.May 07, 2004

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Pubmed Data : Lancet. 2004 May 8 ;363(9420):1509-13. PMID: 15135598

Article Published Date : May 07, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Polio

Pharmacological Actions : Antiviral Agents

Anti Therapeutic Actions : Vaccination: Polio

[+]

Intravenous vitamin C as ancillary treatment for cranial polyneuritis and meningitis due to varicella zoster virus reactivation.May 31, 2020

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Pubmed Data : Antiviral Res. 2007 Oct;76(1):1-10. Epub 2007 May 15. PMID: 17573133

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Rock-rose

Diseases : Avian Influenza

Pharmacological Actions : Antiviral Agents

[+]

A purified extract of Melia azedarach has therapeutic activity against genital herpetic infection in mice.Dec 01, 2009

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Pubmed Data : Phytother Res. 2009 Dec;23(12):1771-7. PMID: 19441066

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Substances : Melia azedarach

Diseases : Genital Herpes, HSV-2

Pharmacological Actions : Antiviral Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

A whole plant extract of artemisia annua was more effective than pure artemisinin, slowing the evolution of malaria drug resistance and overcoming resistance to artemisinin.Jan 19, 2015

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Pubmed Data : Proc Natl Acad Sci U S A. 2015 Jan 20 ;112(3):821-6. Epub 2015 Jan 5. PMID: 25561559

Article Published Date : Jan 19, 2015

Study Type : Animal Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Malaria, Plasmodium Infections

Pharmacological Actions : Antimalarials, Antiviral Agents

Additional Keywords : Bioavailability, Drug Resistance, Plant Extracts, Superiority of Natural Substances versus Drugs, Whole Plant

[+]

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.Dec 31, 2013

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Anti-influenza A virus effects of fructan from Welsh onion.Oct 14, 2012

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Pubmed Data : Food Chem. 2012 Oct 15 ;134(4):2164-8. Epub 2012 Apr 13. PMID: 23442670

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Pubmed Data : Int J Mol Med. 2014 Jul ;34(1):183-90. Epub 2014 Apr 22. PMID: 24756136

Article Published Date : Jun 30, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginseng

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation

Additional Keywords : Plant Extracts

[+]

Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

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Pubmed Data : J Int Med Res. 2009 May-Jun;37(3):662-7 PMID: 19589248

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Astragalus

Diseases : Hepatitis B

Pharmacological Actions : Antiviral Agents

[+]

Astragalus polysaccharides inhibit avian infectious bronchitis virus infection (coronaviridiae) by regulating viral replication.Jan 01, 2018

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Pubmed Data : Microb Pathog. 2018 Jan ;114:124-128. Epub 2017 Nov 21. PMID: 29170045

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Pubmed Data : Biomol Ther (Seoul). 2015 Jul ;23(4):345-9. Epub 2015 Jul 1. PMID: 26157551

Article Published Date : Jun 30, 2015

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Pubmed Data : Nutrients. 2019 Aug 13 ;11(8). Epub 2019 Aug 13. PMID: 31412594

Article Published Date : Aug 12, 2019

Study Type : Animal Study

Additional Links

Substances : Ginseng

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

[+]

Black raspberry seed and gallic acid show potent and broad antiviral activity against influenza A and B type viruses.Dec 31, 2015

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Chrysin derivatives could be beneficial in coxsackievirus infections. Aug 31, 2015

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Pubmed Data : Bing Du Xue Bao. 2009 Jan;25(1):41-6. PMID: 19437885

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Gardenia

Diseases : Herpes Simplex Virus Type 1

Pharmacological Actions : Antiviral Agents

[+]

Garlic contains a compound known as allitridin which has therapeutic activity comparable to the antiviral drug ganiciclovir in a mouse model of cytomegalovirus hepatitis. Feb 01, 2004

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Pubmed Data : Antiviral Res. 2004 Feb;61(2):125-8. PMID: 14670586

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Pubmed Data : Antiviral Res. 1995 May;27(1-2):19-37. PMID: 7486956

Article Published Date : May 01, 1995

Study Type : Animal Study

Additional Links

Substances : Clove, Geum japonicum , Rhus javanica, Terminalia

Diseases : HSV-1

Pharmacological Actions : Antiviral Agents

[+]

Click here to read the entire abstract

Pubmed Data : PLoS One. 2011 ;6(5):e18360. Epub 2011 May 25. PMID: 21904594

Article Published Date : Jan 01, 2011

Study Type : Transgenic Animal Study

Additional Links

Substances : Isoflavones

Diseases : Polio

Pharmacological Actions : Antiviral Agents

[+]

Isoquercetin inhibit influenza A and B viruses. Nov 01, 2010

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Pubmed Data : Antiviral Res. 2010 Nov;88(2):227-35. Epub 2010 Sep 6. PMID: 20826184

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Isoquercitrin

Diseases : Influenza A, Influenza B

Pharmacological Actions : Antiviral Agents

Additional Keywords : Drug Synergy, Plant Extracts

[+]

Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 feeding enhances humoral immune responses.Oct 31, 2019

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Pubmed Data : J Dairy Sci. 2019 Nov ;102(11):9559-9569. Epub 2019 Sep 5. PMID: 31495632

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Pubmed Data : Brain Res. 2015 Jul 10. Epub 2015 Jul 10. PMID: 26168898

Article Published Date : Jul 09, 2015

Study Type : Animal Study

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Substances : Melatonin, Vitamin C

Diseases : Encephalitis, Oxidative Stress

Pharmacological Actions : Antiviral Agents

Additional Keywords : Significant Treatment Outcome

Problem Substances : Antibiotics

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Melia azedarach has therapeutic activity in treating herpetic ocular disease in mice.Sep 01, 2002

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Pubmed Data : Exp Eye Res. 2002 Sep;75(3):327-34. PMID: 12384095

Pubmed Data : Int J Immunopathol Pharmacol. 2007 Apr-Jun;20(2):349-54. PMID: 17624247

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Pubmed Data : Nutr Cancer. 2008 Mar-Apr;60(2):227-34. PMID: 18579649

Article Published Date : Mar 01, 2008

Study Type : Animal Study

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Substances : Quercetin

Diseases : Influenza in Swine, Swine Flu Associated Virus

Pharmacological Actions : Antiviral Agents

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Quercetin-3 β-O-D-glucoside has potential as a prophylactic against Ebola virus infection.Jun 12, 2016

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Pubmed Data : Virol J. 2019 07 31 ;16(1):94. Epub 2019 Jul 31. PMID: 31366366

Article Published Date : Jan 30, 2019

Study Type : Animal Study, In Vitro Study

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Substances : Rosmarinic acid

Diseases : Enterovirus 71

Pharmacological Actions : Antiviral Agents

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Safety: A 4-week repeated oral dose toxicity study of fucoidan from the Sporophyll of Undaria pinnatifida in Sprague-Dawley rats.Jan 11, 2010

Article Published Date : Jan 15, 2009

Study Type : Animal Study

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Substances : Sulforaphane

Diseases : Oxidative Stress, Respiratory Syncytial Virus Infections, Respiratory Tract Infections

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiviral Agents

[+]

Synergistic combination of N-acetylcysteine and ribavirin to protect from lethal influenza viral infection in a mouse model.Dec 31, 2003

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Pubmed Data : Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):99-102. PMID: 15000873

Article Published Date : Dec 31, 2003

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza A

Pharmacological Actions : Antioxidants, Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Tangeretin from Citrus reticulate inhibits respiratory syncytial virus replication and associated inflammation in vivo.Nov 03, 2015

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Pubmed Data : J Agric Food Chem. 2015 Nov 4 ;63(43):9520-7. Epub 2015 Oct 26. PMID: 26468759

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Pubmed Data : . PMID: 27516987

Article Published Date : Jul 15, 2016

Study Type : Animal Study

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Substances : Garlic

Diseases : Coronavirus Disease

Pharmacological Actions : Antiviral Agents

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The polyphenol content of berries influences their antiviral effects.Jun 30, 2013

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Pubmed Data : J Sci Food Agric. 2013 Jul ;93(9):2239-41. Epub 2013 Jan 28. PMID: 23355221

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Pubmed Data : Viruses. 2019 Aug 8 ;11(8). Epub 2019 Aug 8. PMID: 31398832

Article Published Date : Aug 07, 2019

Study Type : Animal Study

Additional Links

Substances : Silver (nanoparticles)

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Immunomodulatory, Interleukin-1 alpha downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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This study provides insights on the molecular antiviral mechanisms of curcumin and its potential use as an antiviral agent for enveloped viruses.Dec 31, 2012

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Pubmed Data : PLoS One. 2013 ;8(5):e62482. Epub 2013 May 1. PMID: 23658730

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Water-soluble extracts from edible mushrooms (Agaricus bisporus) as inhibitors of hepatitis C viral replication.Jun 18, 2019

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Pubmed Data : Food Funct. 2019 Jun 19 ;10(6):3758-3767. PMID: 31179460

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Pubmed Data : Dent Res J (Isfahan). 2020 Mar-Apr;17(2):114-119. Epub 2020 Mar 17. PMID: 32435433

Article Published Date : Feb 29, 2020

Study Type : In Vitro Study

Additional Links

Substances : Cinnamon

Diseases : Herpes Simplex Virus Type 1

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

[+]

Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor.Jul 07, 2020

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Pubmed Data : J Biomol Struct Dyn. 2020 Jul 8:1-14. Epub 2020 Jul 8. PMID: 32643552

Article Published Date : Jul 07, 2020

Study Type : In Vitro Study

Additional Links

Substances : Ashwagandha

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Identification of bioactive molecules from tea plant as SARS-CoV-2 main protease inhibitors.May 19, 2020

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Pubmed Data : Antiviral Res. 2016 Jun 16 ;132:154-164. Epub 2016 Jun 16. PMID: 27321663

Article Published Date : Jun 15, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cranberry

Diseases : Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

[+]

A crude extract and terpenoid isolated from the leaves of O. sanctum and polyphenol from A. arabica shows promising antiviral effects against H9N2 virus.Jun 04, 2018

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Pubmed Data : BMC Complement Altern Med. 2018 Jun 5 ;18(1):174. Epub 2018 Jun 5. PMID: 29866088

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Pubmed Data : Arch Virol. 2013 Apr ;158(4):799-807. Epub 2012 Nov 28. PMID: 23188495

Article Published Date : Apr 01, 2013

Study Type : In Vitro Study

Additional Links

Substances : Probiotics

Diseases : Coronavirus Disease, Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

A review of curcumin as a multifaceted compound against human papilloma virus infection and cervical cancersNov 28, 2016

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Pubmed Data : Biofactors. 2016 Nov 29. Epub 2016 Nov 29. PMID: 27896883

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Pubmed Data : Biofactors. 2008;33(2):85-97. PMID: 19346584

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Proprietary Nutrient Formulas

Diseases : Avian Influenza

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

A water extract of dandelion exhibits anti-influenza activity. Dec 14, 2011

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Pubmed Data : Virol J. 2011 Dec 14 ;8(1):538. Epub 2011 Dec 14. PMID: 22168277

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Pubmed Data : Fitoterapia. 2010 Sep;81(6):600-6. Epub 2010 Mar 20. PMID: 20227470

Article Published Date : Sep 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Potato

Diseases : Brain Cancer, Breast Cancer, Cancers: Canine,

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View the Evidence: 913 Abstracts with Antiviral Agents Research

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2014 Cochrane: a dose-response effect on psychiatric events. In trials of prevention in adults one person was harmed for every 94 treated. Apr 09, 2014

C. papaya leaf extract can be considered as a potential candidate for increase in platelet count in patients of dengue.Sep 30, 2016

Carica papaya extract in dengue: a systematic review and meta-analysis.Oct 10, 2019

Evidence indicates that echinacea potently lowers the risk of recurrent respiratory infections and complications.Feb 28, 2015

P. sidoides might offer symptom relief in acute bronchitis, rhinosinusitis and the common cold.Oct 21, 2013

Supplementation with elderberry was found to substantially reduce upper respiratory symptoms. Jan 31, 2019

These findings suggest that a prolonged course of oral N-acetylcysteine prevents acute exacerbations of chronic bronchitis.Jan 31, 2000

Bee products are effective in symptomatic treatment of upper respiratory tract infections.Dec 31, 2019

A Chinese herbal formula containing Paris polyphylla, Dandelion, Woad, and Licorice appears safe and effective in reducing cytomegalovirus infection activity in pregnant women. Apr 01, 2000

A formulation of 0.5% propolis extract lip balm was found to be superior in the treatment of episodes of herpes labialis over 5% aciclovir cream.Dec 31, 2017

A lead in course with intravenous silibinin prior to the initiation of triple therapy resulted in a 63% sustained virologic response rate in 10/16 HIV/HCV coinfected patients.Dec 31, 2014

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A yeast-based fermentation byproduct reduces cold and flu incidence in nonvaccinated individuals.Feb 01, 2010

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

An extract of Pelargonium sidoides significantly reduces the severity of symptoms and shortens the duration of the common cold.Oct 20, 2017

Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection.Nov 30, 2016

Australian lemon myrtle oil is an effective treatment for molluscum contagiosum in children. May 01, 2004

AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance.Nov 30, 2015

Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection.May 13, 2012

Bitter melon contains compounds with anti-HIV activity. Aug 01, 2000

Broad-band ultraviolet B phototherapy in zoster patients may reduce the incidence and severity of postherpetic neuralgia.Oct 01, 2006

Carica papaya leaf extract increases the platelet count in dengue fever without any side effect and prevents the complication of thrombocytopenia.Dec 31, 2015

Chinese medicine has potential benefits for patients with severe acute respiratory syndrome (SARS) or SARS-like infections.Jul 01, 2006

Chinese medicine seems to enhance survival outcomes in severe acute respiratory syndrome patients.Jan 01, 2006

Chlorella significantly increases the antibody response to influenza vaccination in patients age 50-55 years old. Jul 22, 2003

Cryotherapy is a method with a high success rate in healing of genital warts.Aug 31, 2019

Drinking cocoa could activate natural immunity. Feb 29, 2016

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

Elderberry appears to be safe and effective treatment for influenza A and B. Dec 01, 1995

Elderberry significantly reduces the duration of infection from influenza in a safe manner. Mar 01, 2004

Elderberry stimulates cytokine production in the healthy immune system to fight off viral infection.Apr 01, 2001

Exposure to diesel exhaust leads to increased eosinophil activation and increased virus quantity after virus inoculation in those with allergic rhinitis.Jan 14, 2012

Extracellular polysaccharides produced by Lactobacillus delbrueckii have potential to improve intestinal innate antiviral response.Aug 07, 2017

Garlic extract has potent antiviral activity against human cytomegalovirus. Feb 01, 1993

Green tea drinking suppresses proliferation of HTLV-1-infected lymphocytes in vivo.Jul 01, 2004

Green tea is safe and effective in preventing cold and flu symptoms, and for enhancing T cell function. Oct 01, 2007

Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.Jan 01, 2000

High-dose vitamin D is suitable for the prevention of seasonal influenza as evidenced by rapid relief from symptoms and a decrease in viral loads.Jan 07, 2018

Immune activity against coronavirus infections are improved by omega-6 polyunsaturated fatty acids in turkeys.Sep 01, 1997

Intravenous vitamin C therapy has a positive effect on disease duration and reduces viral antibody levels in EBV infections.Dec 31, 2013

Lactoferrin is a potential useful adjunct treatment for patients with chronic hepatitis C.Oct 31, 2007

Lactoferrin is one potential candidate as an anti‐HCV reagent that may be effective for the treatment of patients with chronic hepatitis.Mar 31, 1999

Melissa officinalis extract is effective for treating herpes simplex labialis. Oct 01, 1999

Natural propolis may be an effective remedy for greating acute and chronic rhinopharyngitis (common cold) in children.Jul 01, 1995

Phyllanthus urinaria consumption reduces detectable hepatitis B e-antigen from the serum of patients with chronic hepatitis B. Oct 01, 1995

Pine cone lignin and ascorbic acid combination has a potent antiviral activity, promoting faster healing, reduction of symptoms and reducing the frequency of recurrence episodes in HSV-1.Oct 31, 2009

Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphomaJan 31, 2018

Practitioners judged homoeopathic treatments as 'successful' in 78.1% of cases vs. 52.2% for conventional therapies for mild viral infections.Aug 31, 2004

Pricking blood therapy combined with ultraviolet irradiation has rapid therapeutic effect, effectively shortens duration of illness, decreases the incidence rate of post herpetic neuralgia and it is a safe remedy for treatment of herpes zoster.Apr 01, 2009

Propolis is superior to the drug acyclovir in the treatment of genital herpes. Mar 01, 2000

Regular coffee consumption is associated with lower rates of disease progression in advanced hepatitis-C related disease. Nov 01, 2009

Rhodiola rosea may exert protective effects against virus replication following intense and prolonged exercise by inducing antiviral activity.Dec 31, 2014

Sandalwood oil appears to be effective in the painless treatment of cutaneous warts caused by human papillomavirus.Dec 31, 2017

Severe acute respiratory syndrome patients treated with a combination of herbal and western medicine saw a significant improvement in arthralgia, myalgia, and arterial oxyhemoglobin. There was a also a non-significant decrease in mortality rate.Jan 01, 2006

Shallomin is a useful natural remedy in preventing the progression and treatment of cold sores.Jul 31, 2014

Silybin supplementation during HCV therapy with pegylated interferon-α plus ribavirin reduces depression and anxiety.Nov 14, 2016

Sinecatechins 10% ointment presents a botanically based alternative to currently available treatments for EGWs that offers a satisfactory balance of clearance rates, reduced frequency of lesion recurrence.Dec 31, 2014

Soy formula and soy isoflavone consumption is associated with reduced rotavirus infectivity. Nov 01, 2009

Spirulina has therapeutic value in hepatitis C patients.Dec 31, 2011

The administration of oral maoto granules to healthy adults with seasonal influenza was well tolerated and associated with equivalent clinical and virological efficacy to oseltamivir or zanamivir.Jul 31, 2012

The traditional Chinese herbal remedy Shuang Huang Lian Wan is as effective penicilin in treating actute tonsilitis, with additional antiviral activity.Sep 01, 2002

There was no difference in efficacy between topical kanuka honey and 5% aciclovir in the pharmacy-based treatment of herpes simplex labialis.May 13, 2019

Topical testosterone appears to increase muscle strength, stimulate albumin synthesis, and improve survival in patients with allograft failure post-liver transplant.Jan 01, 2007

Varicella vaccine has been reported to cause chronic, acyclovir-resistant herpes zoster infection in an immunosuppressed child.Oct 01, 2003

Varicella vaccine has been reported to viral meningitis in an immunocompetent child.Jun 01, 2009

Vitamin D concentrations of 38 ng/ml or more in healthy adults are associated with a significant two-fold reduction in the risk of developing acute viral respiratory tract infection.Jan 01, 2010

Vitamin D decreases hepatitis C virus replication and also contributes to early treatment viral kinetics.Feb 21, 2017

Whole camel milk treatment was able to reduce the viral load in the majority of patients.Mar 31, 2017

Wild Egyptian artichoke exhibits strong antiviral activity against hepatitis C virus and may be useful for its treatment.Jun 13, 2016

Zinc and the Chinese herbal formula Jinye Baidu granule significantly increase the negative conversion rate of HCMV-IgM.May 01, 2005

Zinc may have a therapeutic role in the treatment of human cytomegalovirus infection. Jan 01, 2004

Antiviral Agents

View the Evidence:
913 Abstracts with Antiviral Agents Research