Antiviral Agents

Name	AC	CK
Curcumin	79	104
Lactoferrin	41	71
Elderberry	15	61
Papaya	8	57
Bee Propolis	14	43
Green Tea	14	43
Vitamin D	13	41
EGCG (Epigallocatechin gallate)	29	38
Echinacea	8	37
NAC (N-acetyl-L-cysteine)	14	37
Licorice	23	36
Zinc	17	36
Vitamin C	16	33
Pelargonium sidoides	4	32
Griffithsin	25	31
Fucoidan	16	30
Garlic	15	26
Catechin	7	25
Polyphenols	14	24
Flavonoids	20	21
Ginseng (American)	3	21
Quercetin	19	21
Phyllanthus urinaria	11	20
Dandelion	6	19
Nigella sativa (aka Black Seed)	12	19
Resveratrol	17	17
Spirulina	6	17
Vitamin C: Intravenous	3	16
Ashwagandha	6	15
Cinnamon	5	15
Beta-glucan	4	14
Silymarin	5	14
Berberine	11	13
Holy Basil	4	13
Isoflavones	3	13
Royal Jelly	4	13
Emodin	10	12
Guduchi	3	12
Lactobacillus delbrueckii Subsp	2	12
Propolis: Bee	3	12
Rhodiola (Tibetan Ginseng)	3	12
Silibinin	3	12
Artichoke	2	11
Bee Products	2	11
Coffee	2	11
Fermented Foods and Beverages	2	11
Homeopathic Medicine: All	2	11
Honey	2	11
Milk Thistle	2	11
Neem	10	11
Pine Cone	2	11
Probiotics	8	11
Woad	2	11
Apricot Kernel	1	10
Bitter Melon	1	10
Camel Milk	1	10
Chinese Herbal Formula: Jinye Baidu	1	10
Chinese Herbal Formula: Shuang Huang Lian Wan	1	10
Chinese Skullcap	8	10
Chlorella (Algae)	1	10
Cocoa	1	10
Ephedra sinica (Ma Huang)	1	10
Genistein	8	10
Ginger	5	10
Hesperidin	10	10
Kanuka Honey	1	10
Lemon Myrtle	1	10
Lignans	1	10
Magnesium	1	10
Melissa (Lemonbalm)	1	10
Modified Arabinoxylan Rice Bran (MGN-3)	1	10
Paris polyphylla	1	10
Polyunsaturated Fatty Acids (PUFAs)	1	10
Sandalwood	1	10
Shallot	1	10
Soy Protein	1	10
Testosterone	1	10
Yeast	1	10
Aloe Vera	8	9
Astragalus	6	9
Black Tea	9	9
Ginsenosides	7	9
Glycyrrhizin	9	9
Honeysuckle	7	9
Lemon Balm	9	9
Luteolin	8	9
Naringenin	5	9
Reishi Mushroom	8	9
Artemisinin	6	8
Chaga Mushroom (Inonotus obliquus)	7	8
Herbs: General	7	8
Kaempferol	7	8
Clove	4	7
Geum japonicum	4	7
Ginkgo biloba	6	7
Lactobacillus plantarum	4	7
Lactobacillus probiotics	5	7
Mangiferin	6	7
Pomegranate	7	7
Seaweed	7	7
Theaflavins	7	7
Thymoquinone	6	7
Turmeric	6	7
Algae	4	6
Apigenin	5	6
Blueberry	5	6
Carrageenans	4	6
Carvacrol	5	6
Culinary Herbs and Spices	5	6
Ellagic Acid	6	6
Ginseng	3	6
Medicinal Mushrooms	6	6
Selenium	5	6
Tannic Acid	6	6
Wormwood	5	6
Amla Fruit	1	5
Black Currant	4	5
Caffeic Acid	5	5
Chlorogenic Acid	5	5
Chrysin	4	5
Cranberry	4	5
Fisetin	5	5
Myricetin	5	5
St. Johns Wort	4	5
Sweet Orange	1	5
Vitamin A	4	5
AHCC	2	4
Betulinic acid	3	4
Bromelain	4	4
Cannabidiol	4	4
Gallic Acid	3	4
Ginseng (Korean)	3	4
Houttuynia cordata	3	4
Maitake Mushroom	3	4
Melatonin	3	4
Melia azedarach	2	4
Moringa oleifera	4	4
Mushrooms: All	3	4
Nettle	3	4
Onion	3	4
Patchouli	4	4
Pomegranate Peel	4	4
Prunella vulgaris	3	4
Punicalagin	4	4
Rhubarb	3	4
Rock-rose	3	4
Rosemary	4	4
Rosmarinic acid	3	4
Rutin	4	4
Schisandra	3	4
Sulforaphane	3	4
Terminalia	2	4
Ursolic Acid	4	4
Wogonin	4	4
Xanthohumol	3	4
Almond	3	3
Artesunate	3	3
Bamboo	3	3
Banaba	3	3
Bee Venom	2	3
Bilberry	2	3
Bisdemethoxycurcumin	2	3
Black Raspberry Seed	2	3
Burdock	2	3
Cannabis	2	3
Demethoxycurcumin	2	3
Eugenol	2	3
Ferulic acid	3	3
Gingerol	3	3
Grape Seed Extract	3	3
Guava	3	3
Honokiol	3	3
Horse Chestnut	2	3
Isoliquiritigenin	2	3
Lotus	3	3
Lysine	3	3
Mulberry	3	3
Nobiletin	3	3
Noni	3	3
Nordihydroguaiaretic acid (NDGA)	3	3
Oleuropein	3	3
Olive leaf extract	3	3
Omega-3 Fatty Acids	3	3
Oregano	3	3
Peppermint	3	3
Puerarin	3	3
Pycnogenol (Pine Bark)	2	3
Red Marine Algae	2	3
Sage	3	3
Silver (nanoparticles)	2	3
Tangeretin	2	3
Tetrahydrocurcumin	2	3
Ume (Japanese apricot)	3	3
White Mulberry	3	3
Zataria multiflora	2	3
Adlay	2	2
Angelica	2	2
Arctigenin	1	2
Babchi	2	2
Baicalein	2	2
Banana	2	2
Bifidobacterium Longum	1	2
Bioflavonoids	2	2
Black Pepper	2	2
Blackberry	2	2
Boswellia	2	2
Bran	1	2
Capsaicin	2	2
Celastrol	1	2
Chrysanthemum Indicum	2	2
Cineole	1	2
Cinnamaldehyde	2	2
Clinacanthus siamensis	1	2
Coconut	1	2
Coconut Husk/Fiber	1	2
Cordyceps sinensis	1	2
Delphinidin	2	2
Dihydrocurcumin	1	2
Epicatechin	2	2
Eucalyptus	2	2
False Black Pepper	2	2
Feverfew	2	2
Fig	2	2
Formononetin	2	2
Frankincense	2	2
Fulvic Acid	2	2
Gardenia	1	2
Hibiscus	2	2
Hibiscus sabdariffa	2	2
Hops	2	2
Hydroxytyrosol	2	2
Hyssop	2	2
Isomangiferin	2	2
Isoquercitrin	1	2
Japanese Herbal Formula: Sho-seiryu-to	1	2
Kimchi	1	2
Kombucha Tea	1	2
Lactobacillus gasseri	1	2
Lactobacillus paracasei	1	2
Lychee	2	2
Mangosteen	2	2
Marigold	2	2
Myrrh	2	2
Oak	2	2
Oleanolic acid	2	2
Olive	2	2
Orange: Mandarin	1	2
Panax Ginseng	1	2
Peony	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Pine Bark Extract	2	2
Piperine	2	2
Plantago	2	2
Proanthocyanidins	2	2
Psychedelics:All	2	2
Purslane	2	2
Radix Isatidis	2	2
Rhus javanica	1	2
Rice Bran	1	2
Rose	2	2
Rosemaric Acid	2	2
Saffron	2	2
Sophora Flavescens	2	2
Soy	2	2
Sumac	1	2
Syrian rue	2	2
Thymol	2	2
Tomatidine	2	2
Toona sinensis	2	2
Verbascoside	2	2
Watermelon	1	2
Yoghurt	1	2
7-epi-nemorosone	1	1
Acacia arabica	1	1
Acacia catechu	1	1
Achillea fragrantissima	1	1
Acorus calamus	1	1
Agrimony	1	1
Allicin	1	1
Alpha Linolenic Acid	1	1
Alpha-Lipoic Acid	1	1
Andrographis	1	1
Anise	1	1
Anthocyanins	1	1
Antrodia camphorata	1	1
Antrodia cinnamomea	1	1
Apple Pectin	1	1
Arginine	1	1
Asafoetida	1	1
Asiatic Acid	1	1
Astragaloside	1	1
Avocado	1	1
Bacillus subtilis	1	1
Bael	1	1
Bai Zhu	1	1
Basil	1	1
Basil: Sweet	1	1
Bay leaf	1	1
Bee Pollen	1	1
Benzyl isothiocyanate	1	1
Berries: All	1	1
Biochanin A	1	1
Black Tea Theaflavins	1	1
Blue-Green Algae	1	1
Boneset	1	1
Breast Milk	1	1
Butyrate	1	1
Byrsonima verbascifolia	1	1
Cafestol	1	1
Caffeic acid phenethyl ester	1	1
Carnosic Acid	1	1
Carnosine	1	1
Carrot	1	1
Cashew	1	1
Cat's Claw	1	1
Cayenne	1	1
Cherry: All Varieties	1	1
Chili pepper	1	1
Chrysanthemum Morifolium	1	1
Cinnamic acid	1	1
Citrus Pectin	1	1
Citrus naringin	1	1
Clausena excavata	1	1
Coleus Forskohlii	1	1
Coptidis rhizoma	1	1
Cordyceps Militaris	1	1
Crocetin	1	1
Crocin	1	1
Curcuma phaeocaulis	1	1
Curcuminoids	1	1
DHEA (Dehydroepiandrosterone)	1	1
Daidzein	1	1
Date Seeds	1	1
Diosgenin	1	1
Diosmetin	1	1
Eleutherococcus senticosus	1	1
Essential Oils: Unspecified	1	1
Eugenia dysenterica	1	1
Euphorbia	1	1
Euphorbia peplus	1	1
Euphorbium resinifera	1	1
Fennel	1	1
Flaxseed	1	1
Fructans	1	1
Fructus Ligustri	1	1
Ganoderic acid B	1	1
Garcinia Mangostana	1	1
Garcinia hanburyi	1	1
Geraniol	1	1
Geranium	1	1
Ginseng (Siberian)	1	1
Globularia arabica	1	1
Glutathione	1	1
Glycyrrhiza uralensis	1	1
Grapefruit	1	1
Grapefruit Seed Extract	1	1
Graviola	1	1
Gum arabic	1	1
Gynostemma	1	1
Heal-All	1	1
Honeydew (melon)	1	1
Hu Zhang (Polygonum cuspidatum)	1	1
Humic Acid	1	1
Hydrogen Peroxide	1	1
Hymenaea courbaril	1	1
Indole-3-Carbinol	1	1
Iron	1	1
Japanese cypress	1	1
Japanese mugwort	1	1
Jasonia montana	1	1
Justicia gendarussa	1	1
Kaempferia parviflora	1	1
Kudzu	1	1
Lactobacilius bulgaricus	1	1
Lactobacillus casei	1	1
Lamium album	1	1
Lemon	1	1
Lemon Juice	1	1
Lichens	1	1
Lingonberry	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Loquat	1	1
Luchu Pine	1	1
Magnolia	1	1
Magnolol	1	1
Mango	1	1
Mastic gum	1	1
Mikania micrantha	1	1
Milk	1	1
Monolaurin	1	1
Mosla scabra	1	1
Mugwort	1	1
Mullein	1	1
Mung Bean	1	1
Myracrodruon urundeuva	1	1
Myrica rubra	1	1
Myrtle	1	1
OPC (Oligomeric Proanthocyanidins)	1	1
Oat Bran	1	1
Oligonol	1	1
Oligosaccharides	1	1
Palmitoylethanolamide	1	1
Papain	1	1
Parthenolide	1	1
Pau D'Arco	1	1
Peanut	1	1
Phellinus Linteus	1	1
Phellodendron	1	1
Phloretin	1	1
Phyllanthus amarus	1	1
Piperlongumine	1	1
Pistachio nut	1	1
Plant Sterols/Stanols	1	1
Plantago asiatica	1	1
Plukenetione A	1	1
Plum	1	1
Polygonum multiflorum	1	1
Potato	1	1
Prickly Pear Cactus	1	1
Procyanidin B2	1	1
Proprietary Nutrient Formulas	1	1
Pulsatilla pratensis	1	1
Quassia	1	1
Quinic acid	1	1
Raoulia australis	1	1
Raspberry	1	1
Raw Milk	1	1
Red Sage	1	1
Rhizoma cibotte	1	1
Riboflavin (Vitamin B-2)	1	1
Rooibos	1	1
Rosemary: Essential Oil	1	1
Rubia Cordifolia	1	1
Saikosaponin	1	1
Sappanwood	1	1
Sarsaparilla	1	1
Satsuma	1	1
Saxifraga melanocentra	1	1
Sea buckthorn	1	1
Seaweed: Brown	1	1
Sesamin	1	1
Solasodine glycoalkaloids	1	1
Sophorae Radix	1	1
Star Anise (Illicium anisatum)	1	1
Stilbenes	1	1
Strawberry	1	1
Sweet Acacia	1	1
Tabebuia	1	1
Tamanu	1	1
Tansy	1	1
Tarragon	1	1
Tea	1	1
Tea: Oolong	1	1
Terminalia chebula	1	1
Thyme	1	1
Trigonostema xyphophylloides	1	1
Tripterygium wilfordii	1	1
Tuberaria	1	1
Umcka	1	1
Vatica astrotricha	1	1
Vinegar	1	1
Vitamin B-12	1	1
Vitamin E	1	1
Vitexins	1	1
Whey	1	1
Wild Quinine	1	1
Wrightia tinctoria	1	1
Xanthones	1	1
Ylang-ylang	1	1
Zhu Ling Mushroom	1	1

[+]

2014 Cochrane: a dose-response effect on psychiatric events. In trials of prevention in adults one person was harmed for every 94 treated. Apr 09, 2014

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Pubmed Data : Cochrane Database Syst Rev. 2014 Apr 10(4):CD008965. Epub 2014 Apr 10. PMID: 24718923

Article Published Date : Apr 09, 2014

Study Type : Meta Analysis

Additional Links

Pharmacological Actions : Antiviral Agents, Enzyme Inhibitors

Additional Keywords : Randomized Controlled Trials As Topic

Problem Substances : Oseltamivir (trade name Tamiflu)

[+]

Anti-influenza with green tea catechins.Jun 29, 2021

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Pubmed Data : Turk J Pediatr. 2020 ;62(4):634-640. PMID: 32779416

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Bee Products, Bee Propolis, Honey, Royal Jelly

Diseases : Upper Respiratory Infections

Pharmacological Actions : Anti-Bacterial Agents, Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

[+]

A Pelargonium Sidoides root extract is effective and safe in patients with the common cold.Jan 31, 2019

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Pubmed Data : Integr Med (Encinitas). 2019 Feb ;18(1):42-51. PMID: 31341433

Article Published Date : Jan 31, 2019

Study Type : Human Study

Additional Links

Substances : Germanium

Diseases : Common Cold

Pharmacological Actions : Antiviral Agents

[+]

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

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Pubmed Data : Altern Ther Health Med. 2017 Oct 21. Epub 2017 Oct 21. PMID: 29055287

Article Published Date : Oct 20, 2017

Study Type : Human Study

Additional Links

Substances : Pelargonium sidoides

Diseases : Cold: Common

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts, Risk Reduction

[+]

Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection.Nov 30, 2016

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Pubmed Data : J Altern Complement Med. 2006 Jul-Aug;12(6):505-6. PMID: 16884338

Article Published Date : Jul 01, 2006

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

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Pubmed Data : Curr Ther Res Clin Exp. 2015 Dec ;77:66-72. Epub 2015 Apr 20. PMID: 26265958

Article Published Date : Nov 30, 2015

[+]

Lactoferrin is a potential useful adjunct treatment for patients with chronic hepatitis C.Oct 31, 2007

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Pubmed Data : J Gastroenterol Hepatol. 2007 Nov ;22(11):1894-7. PMID: 17914966

Article Published Date : Oct 31, 2007

Study Type : Human Study

Additional Links

Substances : Lactoferrin

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

[+]

Lactoferrin is one potential candidate as an anti‐HCV reagent that may be effective for the treatment of patients with chronic hepatitis.Mar 31, 1999

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Pubmed Data : Hepatology. 2009 Nov;50(5):1360-9. PMID: 19676128

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

Additional Keywords : Risk Reduction

[+]

Rhodiola rosea may exert protective effects against virus replication following intense and prolonged exercise by inducing antiviral activity.Dec 31, 2014

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Pubmed Data : BMC Psychiatry. 2016 Nov 15 ;16(1):398. Epub 2016 Nov 15. PMID: 27842532

Article Published Date : Nov 14, 2016

Study Type : Human Study

Additional Links

Substances : Silymarin

Diseases : Anxiety Disorders, Depression, Hepatitis C

Pharmacological Actions : Antioxidants, Antiviral Agents

Additional Keywords : Antioxidants, Antiviral Agents, Anxiety Disorders, Depression, hepatitis C, SILYMARIN

[+]

Sinecatechins 10% ointment presents a botanically based alternative to currently available treatments for EGWs that offers a satisfactory balance of clearance rates, reduced frequency of lesion recurrence.Dec 31, 2014

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Pubmed Data : Skin Therapy Lett. 2015 Jan-Feb;20(1):6-8. PMID: 25807215

Pubmed Data : J Infect Chemother. 2012 Aug ;18(4):534-43. Epub 2012 Feb 16. PMID: 22350323

Article Published Date : Jul 31, 2012

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Pubmed Data : Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2002 Sep;16(9):475-6. PMID: 15515537

Article Published Date : Sep 01, 2002

Study Type : Human Study

Additional Links

Substances : Chinese Herbal Formula: Shuang Huang Lian Wan

Diseases : Tonsillitis

Pharmacological Actions : Antiviral Agents

Additional Keywords : Antibiotic Alternatives, Drug: Penicillin, Natural Substances Versus Drugs

[+]

There was no difference in efficacy between topical kanuka honey and 5% aciclovir in the pharmacy-based treatment of herpes simplex labialis.May 13, 2019

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Pubmed Data : Hepatol Res. 2017 Feb 22. Epub 2017 Feb 22. PMID: 28225575

Article Published Date : Feb 21, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

[+]

Whole camel milk treatment was able to reduce the viral load in the majority of patients.Mar 31, 2017

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Pubmed Data : Mol Med Rep. 2014 Apr ;9(4):1381-7. Epub 2014 Jan 29. PMID: 24481875

Article Published Date : Mar 31, 2014

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Dandelion

Diseases : Hepatitis B

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

[+]

A case report of a patient with Chikungunya fever responding swiftly and positively to intravenous vitamin C therapy. Dec 31, 2013

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A polyphenol rich extract of Cistus incanus (Rock-rose family) exhibits potent anti-influenza activity against avian flu virus (H7N7) in mice. Oct 01, 2007

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Pubmed Data : Antiviral Res. 2007 Oct;76(1):1-10. Epub 2007 May 15. PMID: 17573133

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Rock-rose

Diseases : Avian Influenza

Pharmacological Actions : Antiviral Agents

[+]

A purified extract of Melia azedarach has therapeutic activity against genital herpetic infection in mice.Dec 01, 2009

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Pubmed Data : Phytother Res. 2009 Dec;23(12):1771-7. PMID: 19441066

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Substances : Melia azedarach

Diseases : Genital Herpes, HSV-2

Pharmacological Actions : Antiviral Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

A whole plant extract of artemisia annua was more effective than pure artemisinin, slowing the evolution of malaria drug resistance and overcoming resistance to artemisinin.Jan 19, 2015

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Pubmed Data : Proc Natl Acad Sci U S A. 2015 Jan 20 ;112(3):821-6. Epub 2015 Jan 5. PMID: 25561559

Article Published Date : Jan 19, 2015

Study Type : Animal Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Malaria, Plasmodium Infections

Pharmacological Actions : Antimalarials, Antiviral Agents

Additional Keywords : Bioavailability, Drug Resistance, Plant Extracts, Superiority of Natural Substances versus Drugs, Whole Plant

[+]

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.Dec 31, 2013

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Pubmed Data : Am J Chin Med. 2012 ;40(4):801-12. PMID: 22809033

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Pubmed Data : Biotechnol Lett. 2006 Jun ;28(11):837-41. Epub 2006 May 31. PMID: 16786250

Article Published Date : May 31, 2006

Study Type : Animal Study

Additional Links

Substances : Reishi Mushroom

Diseases : Hepatitis B

Pharmacological Actions : Antiviral Agents, Hepatoprotective

[+]

Anti-influenza A virus effects of fructan from Welsh onion.Oct 14, 2012

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Pubmed Data : Food Chem. 2012 Oct 15 ;134(4):2164-8. Epub 2012 Apr 13. PMID: 23442670

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Pubmed Data : Int J Mol Med. 2014 Jul ;34(1):183-90. Epub 2014 Apr 22. PMID: 24756136

Article Published Date : Jun 30, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginseng

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation

Additional Keywords : Plant Extracts

[+]

Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

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Pubmed Data : J Int Med Res. 2009 May-Jun;37(3):662-7 PMID: 19589248

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Astragalus

Diseases : Hepatitis B

Pharmacological Actions : Antiviral Agents

[+]

Astragalus polysaccharides inhibit avian infectious bronchitis virus infection (coronaviridiae) by regulating viral replication.Jan 01, 2018

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Pubmed Data : Microb Pathog. 2018 Jan ;114:124-128. Epub 2017 Nov 21. PMID: 29170045

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Pubmed Data : Front Pharmacol. 2020 ;11:01298. Epub 2020 Oct 6. PMID: 33117149

Article Published Date : Dec 31, 2019

Study Type : Animal Study

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Substances : Flavonoids

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

[+]

Berbamine inhibits Japanese encephalitis virus (JEV) infection.Nov 30, 2021

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Pubmed Data : Biomol Ther (Seoul). 2015 Jul ;23(4):345-9. Epub 2015 Jul 1. PMID: 26157551

Article Published Date : Jun 30, 2015

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Pubmed Data : Nutrients. 2019 Aug 13 ;11(8). Epub 2019 Aug 13. PMID: 31412594

Article Published Date : Aug 12, 2019

Study Type : Animal Study

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Substances : Ginseng

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

[+]

Black raspberry seed and gallic acid show potent and broad antiviral activity against influenza A and B type viruses.Dec 31, 2015

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Chrysin derivatives could be beneficial in coxsackievirus infections. Aug 31, 2015

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Pubmed Data : Carbohydr Polym. 2022 Jan 1 ;275:118779. Epub 2021 Oct 16. PMID: 34742404

Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection.Feb 10, 2019

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Pubmed Data : Bing Du Xue Bao. 2009 Jan;25(1):41-6. PMID: 19437885

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Gardenia

Diseases : Herpes Simplex Virus Type 1

Pharmacological Actions : Antiviral Agents

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Garlic contains a compound known as allitridin which has therapeutic activity comparable to the antiviral drug ganiciclovir in a mouse model of cytomegalovirus hepatitis. Feb 01, 2004

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Pubmed Data : Antiviral Res. 2004 Feb;61(2):125-8. PMID: 14670586

Article Published Date : Feb 01, 2004

Study Type : Animal Study

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Substances : Garlic

Diseases : Cytomegalovirus Infections

Pharmacological Actions : Antiviral Agents

Additional Keywords : Allitridin, Natural Substances Versus Drugs

[+]

Gastrodin inhibits virus infection by promoting the production of type I interferon.Dec 31, 2019

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Pubmed Data : Antiviral Res. 1995 May;27(1-2):19-37. PMID: 7486956

Article Published Date : May 01, 1995

Study Type : Animal Study

Additional Links

Substances : Clove, Geum japonicum , Rhus javanica, Terminalia

Diseases : HSV-1

Pharmacological Actions : Antiviral Agents

[+]

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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo.Jan 23, 2018

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Pubmed Data : Nat Commun. 2018 09 24 ;9(1):3881. Epub 2018 Sep 24. PMID: 30250170

Article Published Date : Jan 23, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Griffithsin

Diseases : Herpes Simplex Virus Type 2, HIV Infections, Human Papillomavirus (HPV)

Pharmacological Actions : Antiviral Agents

[+]

Griffithsin has antiviral activity against hepatitis C virus. Oct 31, 2011

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Pubmed Data : Molecules. 2021 Dec 31 ;27(1). Epub 2021 Dec 31. PMID: 35011479

Article Published Date : Dec 30, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Herb Bennet

Diseases : Adenoviridae Infections, Bladder Cancer, Herpes Simplex Virus Type 1, Liver Cancer

Pharmacological Actions : Antiproliferative , Antiviral Agents, Apoptotic

Additional Keywords : Plant Extracts

[+]

In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses.Jan 08, 2020

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Pubmed Data : Virol J. 2020 09 9 ;17(1):136. Epub 2020 Sep 9. PMID: 32907596

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Pubmed Data : Antiviral Res. 2014 Nov 20 ;113C:93-102. Epub 2014 Nov 20. PMID: 25446333

Article Published Date : Nov 19, 2014

Study Type : Transgenic Animal Study

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Substances : Pycnogenol (Pine Bark)

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

[+]

Inonotus obliquus polysaccharides may be a potential broad-spectrum antiviral drug against feline viruses.Jan 31, 2017

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Pubmed Data : Int J Biol Macromol. 2017 Feb ;95:160-167. Epub 2016 Nov 16. PMID: 27865960

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Cat Diseases

Pharmacological Actions : Antiviral Agents

Additional Keywords : Polysaccharides

[+]

Isoflavones inhibit highly diverged, neurovirulent vaccine-derived, type2 poliovirus sewage isolates.Jan 01, 2011

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Pubmed Data : PLoS One. 2011 ;6(5):e18360. Epub 2011 May 25. PMID: 21904594

Article Published Date : Jan 01, 2011

Study Type : Transgenic Animal Study

Additional Links

Substances : Isoflavones

Diseases : Polio

Pharmacological Actions : Antiviral Agents

[+]

Isoquercetin inhibit influenza A and B viruses. Nov 01, 2010

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Pubmed Data : Cell Mol Life Sci. 2022 Jun 13 ;79(7):361. Epub 2022 Jun 13. PMID: 35697820

Article Published Date : Jun 12, 2022

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents, Neuroprotective Agents

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Melatonin, minocycline and ascorbic acid have an antiviral effect involving their anti-oxidant properties, and suggesting a potential use of these compounds for human VEE virus infection.Jul 09, 2015

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Pubmed Data : Brain Res. 2015 Jul 10. Epub 2015 Jul 10. PMID: 26168898

Article Published Date : Jul 09, 2015

Study Type : Animal Study

Additional Links

Substances : Melatonin, Vitamin C

Diseases : Encephalitis, Oxidative Stress

Pharmacological Actions : Antiviral Agents

Additional Keywords : Significant Treatment Outcome

Problem Substances : Antibiotics

[+]

Melia azedarach has therapeutic activity in treating herpetic ocular disease in mice.Sep 01, 2002

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Pubmed Data : Exp Eye Res. 2002 Sep;75(3):327-34. PMID: 12384095

Pubmed Data : Int J Immunopathol Pharmacol. 2007 Apr-Jun;20(2):349-54. PMID: 17624247

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Pubmed Data : Nutr Cancer. 2008 Mar-Apr;60(2):227-34. PMID: 18579649

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Influenza in Swine, Swine Flu Associated Virus

Pharmacological Actions : Antiviral Agents

[+]

Quercetin-3 β-O-D-glucoside has potential as a prophylactic against Ebola virus infection.Jun 12, 2016

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Pubmed Data : Virol J. 2019 07 31 ;16(1):94. Epub 2019 Jul 31. PMID: 31366366

Article Published Date : Jan 30, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Rosmarinic acid

Diseases : Enterovirus 71

Pharmacological Actions : Antiviral Agents

[+]

Safety: A 4-week repeated oral dose toxicity study of fucoidan from the Sporophyll of Undaria pinnatifida in Sprague-Dawley rats.Jan 11, 2010

Article Published Date : Jan 15, 2009

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Oxidative Stress, Respiratory Syncytial Virus Infections, Respiratory Tract Infections

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiviral Agents

[+]

Synergistic combination of N-acetylcysteine and ribavirin to protect from lethal influenza viral infection in a mouse model.Dec 31, 2003

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Pubmed Data : Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):99-102. PMID: 15000873

Article Published Date : Dec 31, 2003

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza A

Pharmacological Actions : Antioxidants, Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Tangeretin from Citrus reticulate inhibits respiratory syncytial virus replication and associated inflammation in vivo.Nov 03, 2015

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Pubmed Data : J Agric Food Chem. 2015 Nov 4 ;63(43):9520-7. Epub 2015 Oct 26. PMID: 26468759

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2013 ;8(5):e62482. Epub 2013 May 1. PMID: 23658730

Article Published Date : Dec 31, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Dengue, Encephalitis: Japanese, Enveloped Viruses, Influenza A, Vaccinia virus

Pharmacological Actions : Anti-Infective Agents, Antiviral Agents

Additional Keywords : Enveloped Viruses

[+]

This study showed that curcumin prevent atherosclerosis progression.Jun 30, 2020

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Pubmed Data : Life Sci. 2020 Jul 1:117658. Epub 2020 Jul 1. PMID: 32621921

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Atherosclerosis, Cytomegalovirus Infections

Pharmacological Actions<

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View the Evidence: 1367 Abstracts with Antiviral Agents Research

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2014 Cochrane: a dose-response effect on psychiatric events. In trials of prevention in adults one person was harmed for every 94 treated. Apr 09, 2014

Anti-influenza with green tea catechins.Jun 29, 2021

C. papaya leaf extract can be considered as a potential candidate for increase in platelet count in patients of dengue.Sep 30, 2016

Carica papaya extract in dengue: a systematic review and meta-analysis.Oct 10, 2019

Evidence indicates that echinacea potently lowers the risk of recurrent respiratory infections and complications.Feb 28, 2015

Honeysuckle combined with conventional therapy may be beneficial for the treatment of COVID-19 in improving lung CT, clinical cure rate, clinical symptoms.Dec 31, 2020

P. sidoides might offer symptom relief in acute bronchitis, rhinosinusitis and the common cold.Oct 21, 2013

Supplementation with elderberry was found to substantially reduce upper respiratory symptoms. Jan 31, 2019

These findings suggest that a prolonged course of oral N-acetylcysteine prevents acute exacerbations of chronic bronchitis.Jan 31, 2000

Bee products are effective in symptomatic treatment of upper respiratory tract infections.Dec 31, 2019

20-week study of clinical outcomes of over-the-counter COVID-19 prophylaxis and treatment.Dec 31, 2020

A Chinese herbal formula containing Paris polyphylla, Dandelion, Woad, and Licorice appears safe and effective in reducing cytomegalovirus infection activity in pregnant women. Apr 01, 2000

A formulation of 0.5% propolis extract lip balm was found to be superior in the treatment of episodes of herpes labialis over 5% aciclovir cream.Dec 31, 2017

A lead in course with intravenous silibinin prior to the initiation of triple therapy resulted in a 63% sustained virologic response rate in 10/16 HIV/HCV coinfected patients.Dec 31, 2014

A Pelargonium Sidoides root extract is effective and safe in patients with the common cold.Jan 31, 2019

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A yeast-based fermentation byproduct reduces cold and flu incidence in nonvaccinated individuals.Feb 01, 2010

Addition of epigallocatechin gallate 400 mg to sofosbuvir 400 mg + daclatisvir 60 mg in in treatment of patients with chronic hepatitis C.Jan 18, 2019

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

An extract of Pelargonium sidoides significantly reduces the severity of symptoms and shortens the duration of the common cold.Oct 20, 2017

Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection.Nov 30, 2016

Australian lemon myrtle oil is an effective treatment for molluscum contagiosum in children. May 01, 2004

AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance.Nov 30, 2015

Ayurvedic treatment can expedite virological clearance, help in faster recovery and concomitantly reduce the risk of viral dissemination.Mar 31, 2021

Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection.May 13, 2012

Bitter melon contains compounds with anti-HIV activity. Aug 01, 2000

Broad-band ultraviolet B phototherapy in zoster patients may reduce the incidence and severity of postherpetic neuralgia.Oct 01, 2006

Carica papaya leaf extract increases the platelet count in dengue fever without any side effect and prevents the complication of thrombocytopenia.Dec 31, 2015

Chinese medicine has potential benefits for patients with severe acute respiratory syndrome (SARS) or SARS-like infections.Jul 01, 2006

Chinese medicine seems to enhance survival outcomes in severe acute respiratory syndrome patients.Jan 01, 2006

Chlorella significantly increases the antibody response to influenza vaccination in patients age 50-55 years old. Jul 22, 2003

Cryotherapy is a method with a high success rate in healing of genital warts.Aug 31, 2019

Drinking cocoa could activate natural immunity. Feb 29, 2016

Echinacea Purpurea for the long-term prevention of viral respiratory tract infections.Dec 31, 2021

Echinacea reduces antibiotic usage in children through respiratory tract infection prevention.Apr 07, 2021

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

Efficacy of diammonium glycyrrhizinate combined with vitamin C for treating hospitalized COVID-19 patients.Jul 25, 2021

Elderberry appears to be safe and effective treatment for influenza A and B. Dec 01, 1995

Elderberry significantly reduces the duration of infection from influenza in a safe manner. Mar 01, 2004

Elderberry stimulates cytokine production in the healthy immune system to fight off viral infection.Apr 01, 2001

Exposure to diesel exhaust leads to increased eosinophil activation and increased virus quantity after virus inoculation in those with allergic rhinitis.Jan 14, 2012

Extracellular polysaccharides produced by Lactobacillus delbrueckii have potential to improve intestinal innate antiviral response.Aug 07, 2017

Garlic extract has potent antiviral activity against human cytomegalovirus. Feb 01, 1993

Green tea drinking suppresses proliferation of HTLV-1-infected lymphocytes in vivo.Jul 01, 2004

Green tea is safe and effective in preventing cold and flu symptoms, and for enhancing T cell function. Oct 01, 2007

Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.Jan 01, 2000

High-dose vitamin D is suitable for the prevention of seasonal influenza as evidenced by rapid relief from symptoms and a decrease in viral loads.Jan 07, 2018

Immune activity against coronavirus infections are improved by omega-6 polyunsaturated fatty acids in turkeys.Sep 01, 1997

Intravenous vitamin C therapy has a positive effect on disease duration and reduces viral antibody levels in EBV infections.Dec 31, 2013

Lactoferrin is a potential useful adjunct treatment for patients with chronic hepatitis C.Oct 31, 2007

Lactoferrin is one potential candidate as an anti‐HCV reagent that may be effective for the treatment of patients with chronic hepatitis.Mar 31, 1999

Melissa officinalis extract is effective for treating herpes simplex labialis. Oct 01, 1999

Natural propolis may be an effective remedy for greating acute and chronic rhinopharyngitis (common cold) in children.Jul 01, 1995

Phyllanthus urinaria consumption reduces detectable hepatitis B e-antigen from the serum of patients with chronic hepatitis B. Oct 01, 1995

Pine cone lignin and ascorbic acid combination has a potent antiviral activity, promoting faster healing, reduction of symptoms and reducing the frequency of recurrence episodes in HSV-1.Oct 31, 2009

Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphomaJan 31, 2018

Practitioners judged homoeopathic treatments as 'successful' in 78.1% of cases vs. 52.2% for conventional therapies for mild viral infections.Aug 31, 2004

Pricking blood therapy combined with ultraviolet irradiation has rapid therapeutic effect, effectively shortens duration of illness, decreases the incidence rate of post herpetic neuralgia and it is a safe remedy for treatment of herpes zoster.Apr 01, 2009

Propolis is superior to the drug acyclovir in the treatment of genital herpes. Mar 01, 2000

Regular coffee consumption is associated with lower rates of disease progression in advanced hepatitis-C related disease. Nov 01, 2009

Rhodiola rosea may exert protective effects against virus replication following intense and prolonged exercise by inducing antiviral activity.Dec 31, 2014

Sandalwood oil appears to be effective in the painless treatment of cutaneous warts caused by human papillomavirus.Dec 31, 2017

Severe acute respiratory syndrome patients treated with a combination of herbal and western medicine saw a significant improvement in arthralgia, myalgia, and arterial oxyhemoglobin. There was a also a non-significant decrease in mortality rate.Jan 01, 2006

Shallomin is a useful natural remedy in preventing the progression and treatment of cold sores.Jul 31, 2014

Silybin supplementation during HCV therapy with pegylated interferon-α plus ribavirin reduces depression and anxiety.Nov 14, 2016

Sinecatechins 10% ointment presents a botanically based alternative to currently available treatments for EGWs that offers a satisfactory balance of clearance rates, reduced frequency of lesion recurrence.Dec 31, 2014

Soy formula and soy isoflavone consumption is associated with reduced rotavirus infectivity. Nov 01, 2009

Spirulina has therapeutic value in hepatitis C patients.Dec 31, 2011

The administration of oral maoto granules to healthy adults with seasonal influenza was well tolerated and associated with equivalent clinical and virological efficacy to oseltamivir or zanamivir.Jul 31, 2012

The effects of combination of Zingiber officinale and Echinacea on alleviation of clinical symptoms and hospitalization rate of suspected COVID-19 outpatients.Mar 30, 2021

The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients.Jan 04, 2022

Antiviral Agents

View the Evidence:
1367 Abstracts with Antiviral Agents Research