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Apoptotic
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772 Substances Researched for Apoptotic
Name
AC
CK
Focus
Curcumin
477
595
Resveratrol
161
196
Ginsenosides
138
160
Sulforaphane
95
157
Flavonoids
124
144
EGCG (Epigallocatechin gallate)
79
120
Thymoquinone
79
104
Quercetin
84
93
Vitamin C
63
88
Tanshinone IIA
75
83
Genistein
63
79
Berberine
62
72
Oridonin
59
69
Polyphenols
56
68
Licorice
59
67
Melatonin
46
67
Apigenin
45
65
Cannabinoids
47
64
Shikonin
50
64
Luteolin
56
63
Fucoidan
56
62
Silibinin
41
62
Honokiol
43
61
Cucurbitacin B
41
58
Indole-3-Carbinol
40
55
Catechin
38
54
Beta-Elemene
48
52
Pterostilbene
43
49
Ursolic Acid
37
47
Garlic
34
46
Xanthohumol
40
46
Betulinic acid
39
45
Myricetin
37
45
Capsaicin
15
44
Parthenolide
32
44
Cannabidiol
35
43
Delta-tetrahydrocannabinol (THC)
27
42
Deguelin
33
41
Fisetin
37
41
Green Tea
25
41
Wogonin
28
40
Grape Seed Extract
23
39
Reishi Mushroom
29
39
Emodin
30
38
Astaxanthin
22
37
Chrysin
28
37
Isoflavones
21
37
Piperlongumine
27
37
Vitamin E
22
37
Isoliquiritigenin
27
36
Ginger
27
35
Bee Venom
20
33
Anthocyanins
21
32
Fermented Foods and Beverages
19
31
Baicalein
23
30
Ellagic Acid
23
30
Moringa oleifera
24
30
Mulberry
20
29
NAC (N-acetyl-L-cysteine)
11
29
Turmeric
24
29
Bufalin
25
28
Phellinus Linteus
23
28
Vitamin D
26
28
Cannabinoids: Synthetic
16
27
Nigella sativa (aka Black Seed)
19
27
Artemisinin
23
26
Gingerol
20
26
Huaier (Trametes robiniophila murr)
22
26
Piperine
19
26
Ashwagandha
18
25
Formononetin
19
25
Frankincense
13
25
Kaempferol
23
25
Lichens
20
25
Lotus
23
25
Magnolol
17
25
Paeonol
20
25
Lycopene
14
24
Mistletoe
12
24
Tocotrienol: Delta
10
24
6-Shogaol
20
23
Daidzein
10
23
Graviola
8
23
Isothiocyanates
20
23
Lactoferrin
21
23
Naringenin
18
23
Paeoniflorin
19
23
Stilbenes
20
23
Fucoxanthin
16
22
Puerarin
19
22
Piceatannol
20
21
Arctigenin
14
20
Bromelain
12
20
Carnosic Acid
15
20
Citral
6
20
Cordyceps Militaris
19
20
Crocin
17
20
Curcumol
16
20
Diosgenin
18
20
Flaxseed
9
20
Ginkgo biloba
15
20
Milk Thistle
8
20
Tomato
7
20
Angelica
7
19
Blueberry
11
19
Chaga Mushroom (Inonotus obliquus)
12
19
Homeopathic Medicine: All
15
19
Maitake Mushroom
11
19
Raspberry
13
19
Toona sinensis
11
19
Allicin
17
18
Artesunate
16
18
Asiatic Acid
15
18
Gallic Acid
16
18
Peony
16
18
Pomegranate
11
18
Caffeic Acid
7
17
Dandelion
11
17
Demethoxycurcumin
14
17
Nobiletin
15
17
Phloretin
16
17
Spirulina
9
17
Tetrahydrocurcumin
10
17
Zerumbone
13
17
Bee Propolis
15
16
DHA (Docosahexaenoic Acid)
13
16
Gold (nanoparticles)
15
16
Neem
11
16
Benzyl isothiocyanate
13
15
Cannabis
14
15
Carotenoids
5
15
Cruciferous Vegetables
10
15
EPA (Eicosapentaenoic Acid)
4
15
Mangosteen
8
15
Medicinal Mushrooms
12
15
Oleuropein
14
15
Aloe Vera
12
14
Black Tea
10
14
Cinnamon
11
14
Ginseng
8
14
Iodine
4
14
Mushrooms: All
8
14
Selenium
12
14
Water: Deuterium Depleted
4
14
Wheat Germ
9
14
Astragaloside
12
13
Berbamine
12
13
Bisdemethoxycurcumin
11
13
Black Raspberry
4
13
Caffeine
3
13
Camel Milk
4
13
Chinese Skullcap
11
13
Citrus naringin
10
13
Cranberry
9
13
Feverfew
9
13
Kahweol
9
13
Oleanolic acid
11
13
Phenethyl isothiocyanate
10
13
Prunella vulgaris
9
13
Pycnogenol (Pine Bark)
4
13
Rhubarb
9
13
Soy
3
13
Zinc
8
13
Beta Sitosterol
8
12
Biochanin A
11
12
Caffeic acid phenethyl ester
11
12
Carrot
7
12
Cryptoxanthin
3
12
Fenugreek
7
12
Goji
8
12
Hesperidin
10
12
Manuka Honey
7
12
Rose
11
12
Silver (nanoparticles)
11
12
Tangeretin
11
12
Tocotrienol: Gamma
8
12
Vitamin C: Intravenous
4
12
Vitamin E: Gamma-tocotrienol
12
12
Anandamide
9
11
Broccoli
9
11
Celastrol
9
11
Ginseng (Korean)
8
11
Lupeol
9
11
Mangiferin
10
11
Nettle
10
11
Rosemary
7
11
Shiitake Mushroom
7
11
Strawberry
6
11
Vitamin K
10
11
Walnut
11
11
Amygdalin
8
10
Apples
8
10
Babchi
6
10
Bai Zhu
8
10
Blackberry
5
10
Burdock
9
10
Carnosol
9
10
Carvacrol
8
10
Cucurbitacin E
9
10
Curcuminoids
9
10
Eugenol
9
10
Fiber
7
10
Grape
8
10
Kefir
7
10
Lemongrass
4
10
MSM (Methylsulfonylmethane)
7
10
Motherwort
1
10
Olive leaf extract
6
10
Omega-3 Fatty Acids
7
10
Psychedelics:All
9
10
Rutin
8
10
Sesamin
8
10
Sesamol
8
10
Silymarin
8
10
Verbena officinalis
1
10
Wormwood
9
10
Bitter Melon
9
9
Black Pepper
5
9
Bloodroot
5
9
Chlorogenic Acid
9
9
Cinnamaldehyde
7
9
Citrus Peel
7
9
Cucurbitacin D
8
9
Eucalyptus
7
9
Lion's Mane (Hericium Erinaceus)
8
9
Nexrutine (Phellodendrom)
7
9
Orange
7
9
Probiotics
6
9
Red Sage
8
9
Rosemaric Acid
9
9
Sweet Potato: Purple
7
9
Theaflavins
9
9
Tualang Honey
4
9
Vitexins
7
9
Wheat Grass
7
9
Amla Fruit
3
8
Antrodia camphorata
6
8
Avocado
4
8
D-Limonene
7
8
Diosmetin
8
8
Diosmin
6
8
Fig
7
8
Garcinia Mangostana
4
8
Genipin
6
8
Ginseng (Siberian)
4
8
Gynostemma
8
8
Holy Basil
7
8
Honey
7
8
Lignans
6
8
Modified Arabinoxylan Rice Bran (MGN-3)
5
8
Prickly Pear Cactus
7
8
Pumpkin
3
8
Shallot
7
8
Soy Protein
4
8
Tannic Acid
4
8
Verbascoside
5
8
Vitamin E: alpha tocopherol
6
8
Whey
5
8
White Mulberry
4
8
Agaricus Blazei
5
7
Beet
6
7
Bergamot
3
7
Butyrate
7
7
Crocetin
6
7
Curry Leaves
5
7
Delphinidin
7
7
Dogwood
3
7
Fish Oil
4
7
Inositol Hexaphosphate
5
7
Lactobacillus casei
6
7
Lemon
5
7
Lithospermum erythrorhizon
6
7
Nordihydroguaiaretic acid (NDGA)
6
7
Phyllanthus urinaria
7
7
Piperidines
5
7
Safflower
6
7
Saffron
6
7
Sea buckthorn
3
7
Sophora Flavescens
5
7
Soursop
5
7
St. Johns Wort
6
7
Syrian rue
6
7
Tripterygium wilfordii
6
7
Bacopa
5
6
Bamboo
5
6
Bay leaf
6
6
Brown Rice
2
6
Cardamonin
6
6
Cocoa
5
6
Curcumin: Degradiation byproducts
2
6
Endocannabinoids
5
6
Evodiamine
5
6
Fennel
5
6
Indian Gooseberry
2
6
Jujube
5
6
Long Pepper
4
6
Noni
6
6
Oregano
5
6
Panax Ginseng
5
6
Pine Bark Extract
6
6
Polyunsaturated Fatty Acids (PUFAs)
4
6
Proanthocyanidins
5
6
Punicalagin
6
6
Red Clover
5
6
Rosmarinic acid
4
6
Solanum nigrum (black nightshade)
5
6
Sprouts
5
6
Sweet Potato
4
6
Tea
5
6
Vitamin E: Gamma-Tocopherol
2
6
Vitamin K2
5
6
Zyflamend
6
6
beta-Carotene
6
6
Achiote
1
5
Adlay
5
5
Amurensin G
1
5
Andrographis
5
5
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
2
5
Apple Polyphenols
5
5
Barley
3
5
Black Currant
1
5
Broccoli Sprouts
3
5
Cafestol
5
5
Chlorella (Algae)
3
5
Cordyceps sinensis
5
5
Cyanidin 3-glucoside
4
5
Daisy
4
5
Damnacanthal
5
5
Echinacea
4
5
Eriodictyol
4
5
False Black Pepper
5
5
Geranium
3
5
Hawthorn
5
5
Honeysuckle
5
5
Hops
5
5
Hydroxytyrosol
5
5
Ligustrazine
4
5
Lingonberry
1
5
Liquiritigenin
3
5
Litchi
4
5
Nicotinamide adenine dinucleotide (NADH)
3
5
Olive
4
5
Palash
4
5
Panax Notoginseng
5
5
Panaxadiol
1
5
Patchouli
3
5
Pineapple
3
5
Rice
1
5
Sandalwood
5
5
Thymol
5
5
Tocotrienols
4
5
Triptolide
5
5
White Tea
4
5
18β-Glycyrrhetinic Acid
3
4
Alpha-Lipoic Acid
4
4
Alpinia galanga
3
4
Apple
3
4
Astragalus
4
4
Banana
3
4
Bergamot orange
4
4
Boswellia
3
4
CLA (Conjugated Linoleic Acid)
3
4
Chokeberry
4
4
Chrysanthemum Indicum
4
4
Corn Silk
4
4
Coumestrol
4
4
Diallyl sulfide
3
4
Essential Oils: Unspecified
3
4
Ferulic acid
4
4
Gac
3
4
Galbanic Acid
4
4
Geraniol
4
4
Gleditsia sinensis
3
4
Helenalin
4
4
Hibiscus
4
4
Hibiscus sabdariffa
3
4
Hyperforin
4
4
Isoquercitrin
3
4
Japanese mugwort
4
4
Juniper
3
4
Kava Kava
3
4
Kiwifruit
3
4
Lactobacillus Acidophilus
3
4
Lactobacillus paracasei
4
4
Lactobacillus plantarum
4
4
Lutein
4
4
Magnolia
3
4
Marijuana
4
4
Marjoram
4
4
Oyster Mushroom
4
4
Perilla
4
4
Persimmon
4
4
Phyllanthus amarus
4
4
Pleurotus nebrodensis
3
4
Red Wine Extract
4
4
S-Adenosylmethionine (SAMe)
3
4
Sea Cucumber
2
4
Seaweed: Brown
4
4
Shemamruthaa
2
4
Sumac
4
4
Tabebuia
4
4
Thyme
3
4
Trichosanthes Kirilowii
3
4
Vanillin
3
4
Vitamin E: delta-tocopherol
3
4
Wasabi
3
4
Xanthones
4
4
Yerba Santa
2
4
Amygdalin (laetrile)
3
3
Apple Pectin
2
3
Arginine
2
3
Beans: All
3
3
Berries: All
3
3
Beta-Caryophyllene
3
3
Betaine
2
3
Bilberry
2
3
Bile salts
2
3
Bitter Orange
3
3
Buckwheat
2
3
Camptothecin
2
3
Chlorophyllin
2
3
Coffee
3
3
Collagen
2
3
Colloidal Silver
3
3
Cyanidin
3
3
Dibenzoylmethane (DBM)
2
3
Dill
3
3
Dimethyl trisulfide (DMTS)
2
3
False Daisy
2
3
Folate
3
3
Folic Acid
2
3
Garlic: Aged
3
3
Ginseng (American)
3
3
Ginseng, unspecified species
3
3
Harmine
3
3
Insulin-like Growth Factor (IGF-1)
2
3
Lactobacillus rhamnosus
2
3
Lactobacillus rhamnosus GG
3
3
Lysine
3
3
Modified Citrus Pectin
2
3
Mugwort
3
3
Oak
3
3
Okra
3
3
Oleocanthal
3
3
Olive Oil
3
3
P-Coumaric Acid
3
3
Palm Oil
2
3
Passion Flower
2
3
Pea
2
3
Peanut
2
3
Perillaldehyde
2
3
Phyllanthus emblica
3
3
Phyllanthus niruri (Stonebreaker)
3
3
Physalis minima
3
3
Pine Needle
2
3
Plum
3
3
Pomegranate Peel
3
3
Procyanidin B2
3
3
Red Yeast Rice
2
3
Riboflavin (Vitamin B-2)
3
3
Ruta Graveolens
3
3
Sage
3
3
Seaweed
2
3
Spinach
2
3
Theanine
2
3
Thistle
3
3
Tongkat Ali
3
3
Traditional Chinese Medicine: Mylabris
2
3
Turmerones
3
3
Urolithin A
3
3
Venom: Toad
2
3
Vitamin A
3
3
Wheat Bran
2
3
White Button Mushroom
2
3
Zeaxanthin
2
3
acetyl-11-keto-beta-boswellic acid
3
3
phytoestrogens
2
3
Allspice
1
2
Andrographolide
2
2
Anthurium schlechtendalii
1
2
Antioxidant formulas
1
2
Arachidonyl Ethanolamide (AEA)
2
2
Arugula
1
2
Asparagus
2
2
Azelaic Acid
1
2
Banaba
2
2
Barberry
2
2
Bifidobacterium Longum
1
2
Bifidobacterium animalis
1
2
Black Cohosh
2
2
Brown Rice: Pre-Germinated
1
2
Calcium
1
2
Cannabigerol
1
2
Capparis spinosa (caper)
2
2
Cashew
1
2
Catechols
2
2
Chamomile
2
2
Cinnamic acid
1
2
Clove
2
2
Coenzyme Q10
1
2
Coleus Forskohlii
2
2
Cucumber
1
2
Curcuma Longa
2
2
Curcuma Purpurascens
1
2
Dates
2
2
Eurya Emarginata
1
2
Evening Primrose Oil
2
2
Galactooligosaccharides
1
2
Garcinia indica
2
2
Glycoaminoglycans
1
2
Glycyrrhizin
2
2
Goat Milk
1
2
Gotu Kola
2
2
Guggul
2
2
Hazelnut
2
2
Hemp Seed
2
2
Henna
2
2
Hydrogen Peroxide
2
2
Hydrogen Water
1
2
Isothiocyanate
1
2
Jambul
1
2
Kaempferia parviflora
2
2
Kudzu
2
2
Lactobacillus Brevis
1
2
Lactococcus lactis
2
2
Lemon Balm
2
2
Lime: Key
2
2
Loquat
2
2
Lychee
2
2
Magnolia grandifloris (honokiol)
1
2
Mango
2
2
Mastic gum
2
2
Myo-inositol
1
2
Myrrh
2
2
Noni leaf extract
1
2
Onion
2
2
Organosulfur Compounds
2
2
Orthosiphon
2
2
Palmitoylethanolamide
1
2
Papaya
2
2
Paprika
1
2
Pear
2
2
Pecan
1
2
Pectin
1
2
Pistachio nut
2
2
Poria cocos
2
2
Potato
2
2
Potato: Pigmented
1
2
Prebiotics
1
2
Proline
2
2
Propolis: Bee
2
2
Propolis: Brazillian
2
2
Protandim
1
2
Purslane
2
2
Rooibos
2
2
Rose Hips
2
2
Rubia Cordifolia
1
2
Rye
1
2
Saccharomyces Boulardii
1
2
Safranal
2
2
Salvia miltiorrhiza
1
2
Sesame Seeds
2
2
Shitake Mushroom
1
2
Stearic Acid (stearate)
1
2
Stevia
2
2
Terminalia chebula
2
2
Thiamine (B-1)
1
2
Valerian
1
2
Vinegar
1
2
Viruses: Beneficial
1
2
Vitamin B-6
2
2
Vitex negundo
2
2
Water
1
2
Wheat: Fermented
2
2
Yarrow
2
2
Yoghurt
1
2
Zataria multiflora
2
2
vaccine
1
2
2-Methoxyestradiol
1
1
Acai
1
1
Agrimony
1
1
Aleurone
1
1
Algae
1
1
Antineoplastons
1
1
Apricot
1
1
Arabinoxylans
1
1
Arachidin-1
1
1
Argan Oil
1
1
Arnica
1
1
Artichoke
1
1
Avenanthramides
1
1
Bacillus coagulans
1
1
Bael
1
1
Banana Peel
1
1
Barley Grass
1
1
Basil
1
1
Basil: Sweet
1
1
Bee Pollen
1
1
Beer
1
1
Beta-glucan
1
1
Betanins
1
1
Betel
1
1
Bioflavonoids
1
1
Black Bean
1
1
Black Cherry
1
1
Black Tea Theaflavins
1
1
Black hellebore
1
1
Breast Milk
1
1
Brussel sprouts
1
1
Cabbage
1
1
Caffeoylquinic Acids
1
1
Carsonic Acid
1
1
Cassava
1
1
Cat's Claw
1
1
Cautleya gracilis
1
1
Celery
1
1
Celery seed
1
1
Chaste Tree (Chasteberry)
1
1
Chickpea
1
1
Chives
1
1
Chrysanthemum Morifolium
1
1
Cleavers
1
1
Clinacanthus nutans
1
1
Common bean
1
1
Copper
1
1
Coptidis rhizoma
1
1
Coptis chinensis
1
1
Cordyceps pruinosa
1
1
Coriolus versicolor
1
1
Corydalis Yanhusuo
1
1
Cranberry Proanthocyanidins
1
1
Crimini Mushroom
1
1
Cryptomeria japonica
1
1
Curcuma phaeocaulis
1
1
Curry Tree
1
1
Cyclopamine
1
1
Daikon radish
1
1
Decursin
1
1
Deuterium (heavy water)
1
1
Dong Quai
1
1
Dopa bean
1
1
Dragon Fruit
1
1
Egg
1
1
Elderberry
1
1
Elecampane
1
1
Endive (Cichorium endivia. L )
1
1
Epicatechin
1
1
Epimedium
1
1
Erucin
1
1
Essiac Tea
1
1
Feijoa
1
1
Flavan-3-ols
1
1
Flax Straw
1
1
Flaxseed Oil
1
1
Fruit: All
1
1
Fulvic Acid
1
1
Gallotannins
1
1
Gamma-Linoleic Acid (GLA)
1
1
Garcinia dulcis
1
1
Garden Cress (Lepidium sativum)
1
1
Gastrodin
1
1
Glycyrrhiza uralensis
1
1
Gold
1
1
Goldenseal
1
1
Grapefruit
1
1
Greater celandine
1
1
Green Leafy Vegetables
1
1
Guarana
1
1
Guava
1
1
Guduchi
1
1
Gymnema Sylvestre
1
1
Honeybush
1
1
Horsetail
1
1
Hu Zhang (Polygonum cuspidatum)
1
1
Humic Acid
1
1
IP6
1
1
Icariin
1
1
Ice Man Fungus
1
1
Japanese Herbal Formula: Juzen-taiho-to
1
1
Japanese cypress
1
1
Kimchi
1
1
King trumpet mushroom
1
1
Lactobacillus fermentum
1
1
Lactobacillus gasseri
1
1
Lactobacillus probiotics
1
1
Lauric acid
1
1
Leek
1
1
Lettuce
1
1
Lime
1
1
Linoleic acid
1
1
Lobelia
1
1
Loquat Leaves
1
1
Magnesium
1
1
Manganese
1
1
Mango Seed
1
1
Matairesinol
1
1
Melissa (Lemonbalm)
1
1
Menthol
1
1
Methionine
1
1
Milk: Fermented
1
1
Modified Rice Bran (MGN-3)
1
1
Molasses
1
1
Mustard Greens
1
1
Neoxanthin
1
1
Nicotinamide
1
1
Nutmeg
1
1
OPC (Oligomeric Proanthocyanidins)
1
1
Oats
1
1
Oligonol
1
1
Oolong tea
1
1
Orange: Mandarin
1
1
Parsley
1
1
Pau D'Arco
1
1
Peach
1
1
Pelargonium sidoides
1
1
Peppermint
1
1
Phosphatidylserine
1
1
Phytoalexins
1
1
Phytosterols
1
1
Pine Cone
1
1
Pinellia
1
1
Pinus Massoniana Bark
1
1
Plant Sterols/Stanols
1
1
Podophyllum hexandrum
1
1
Pomegranate flower
1
1
Portabella Mushroom
1
1
Potassium
1
1
Progesterone
1
1
Propionibacterium freudenreichii
1
1
Punicic acid
1
1
Radish
1
1
Raisins
1
1
Red Pepper
1
1
Reseda luteola
1
1
Resins
1
1
Riboflavin
1
1
Rice Bran
1
1
Rose: Essential Oil
1
1
SAMe (S-adenosylmethionine)
1
1
Schisandra
1
1
Scutellaria barbata
1
1
Sessile Joyweed
1
1
Smilax glabra
1
1
Soup
1
1
Spikenard
1
1
Stemona tuberosa
1
1
Tarragon
1
1
Taxifolin
1
1
Tea Tree
1
1
Tea: Oolong
1
1
Terminalia
1
1
Tetrahydropalmatine
1
1
Toad
1
1
Tocotrienol: Alpha
1
1
Tribulus
1
1
Triphala
1
1
Turkey Tail Mushroom
1
1
Ume (Japanese apricot)
1
1
Vegetables: All
1
1
Venom: Snake
1
1
Vitamin B-12
1
1
Vitamin B-3 (Niacin)
1
1
Vitamin B12: methylcobalamin
1
1
Vitex Agnus
1
1
Water: Electrolyzed Reduced
1
1
Wedelia chinensis
1
1
Wine
1
1
Yam
1
1
Yeast
1
1
Yucca
1
1
Zhu Ling Mushroom
1
1
neohesperidin
1
1
Research Articles
5304
Cumulative Knowledge Score
8581
Overall Research Rating
EXCELLENT
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View the Evidence:
6730 Abstracts with Apoptotic Research
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[+]
Anthocyanins reduce cell Invasion and migration through Akt/mTOR Downregulation and apoptosis activation in triple-negative breast cancer cells.
Apr 13, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2023 Apr 14 ;15(8). Epub 2023 Apr 14. PMID:
37190229
Article Published Date
: Apr 13, 2023
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Anthocyanins
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells.
May 28, 2022
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2022 May 29 ;105:33-52. Epub 2022 May 29. PMID:
35797732
Article Published Date
: May 28, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Naringenin
Diseases
:
Cancers: All
Pharmacological Actions
:
Apoptotic
[+]
Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.
Oct 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID:
29040973
Article Published Date
: Oct 17, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Sulforaphane
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
This meta-analysis implies moderation in capsaicin consumption in order to derive its protective benefits.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Gastrointest Cancer. 2014 Sep ;45(3):334-41. PMID:
24756832
Article Published Date
: Aug 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Capsaicin
Diseases
:
Gastric Cancer
,
Helicobacter Pylori Infection
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
[+]
Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Biol Toxicol. 2010 Oct;26(5):457-67. Epub 2010 Mar 14. PMID:
20229275
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Immune Disorders: Low Immune Function
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Apoptotic
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.
Sep 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID:
26023082
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study, Human Study, In Vitro Study
Additional Links
Substances
:
Cryptoxanthin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Chemotherapeutic Synergy: Oxaliplatin
[+]
Chinese motherwort has cytotoxicity against human breast cancer cells that is non-apoptic and estrogen receptor independent.
Mar 18, 2009
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 Mar 18;122(2):234-9. PMID:
19330917
Article Published Date
: Mar 18, 2009
Study Type
: Human Study
Additional Links
Substances
:
Motherwort
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
[+]
Curcumin induces programmed cell death in human malignant gliobastoma cells - Article 2.
Oct 16, 2006
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2006 Oct 16;407(1):53-8. Epub 2006 Sep 1. PMID:
16949208
Article Published Date
: Oct 16, 2006
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Cancer
,
Glioblastoma
Pharmacological Actions
:
Apoptotic
[+]
Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Invest Dermatol. 2010 Aug;130(8):2110-9. Epub 2010 Apr 15. PMID:
20393484
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
T-Cell Lymphoma: Cutaneous
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Danggui can prolong the survival rate of gastric cancer patients in Taiwan.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;48(6):2231-2246. Epub 2018 Aug 16. PMID:
30114701
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Angelica
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
EPA (eicosapentaenoic acid) induces programmed cell death in human pancreatic cancer cells.
Oct 01, 2005
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2005 Oct;21(10):1010-7. PMID:
16157238
Article Published Date
: Oct 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Apoptotic
[+]
Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients.
Jun 17, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2022 Jun 18 ;12(1):10303. Epub 2022 Jun 18. PMID:
35717540
Article Published Date
: Jun 17, 2022
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Progesterone
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Grape seed procyanidin extract mediates antineoplastic effects against lung cancer.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2016 Dec ;9(12):925-932. Epub 2016 Sep 22. PMID:
27658889
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Proanthocyanidins
[+]
Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.
Jan 01, 2000
Click here to read the entire abstract
Pubmed Data
: Jpn J Cancer Res. 2000 Jan;91(1):34-40. PMID:
10744042
Article Published Date
: Jan 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Adult T-cell leukemia/lymphoma (ATL)
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiviral Agents
,
Apoptotic
[+]
High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.
Jan 06, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 12 7 ;7(1):17188. Epub 2017 Dec 7. PMID:
29215048
Article Published Date
: Jan 06, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
HLA-DQ2/8 genes may not cause gluten-associated villous atrophy, rather, be activated as a consequence of the pathological process.
Dec 31, 2004
Click here to read the entire abstract
Pubmed Data
: Clin Chem Lab Med. 2005 ;43(7):685-95. PMID:
16207126
Article Published Date
: Dec 31, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
HLA-DQ2/DQ8
,
Questions Of Causality
[+]
Hyperbaric oxygen therapy may be an appropriate therapeutic regimen for the treatment of patients with osteosarcoma.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2009 Nov;22(5):1045-50. PMID:
19787219
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Osteosarcoma
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Drug Synergy
[+]
Metabolised pycnogenol induces apoptosis in human fibrosarcoma cells.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2015 Apr ;46(4):1629-36. Epub 2015 Jan 27. PMID:
25625225
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Fibrosarcoma
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Gene Expression Regulation
,
Natural Substance Synergy
[+]
Mistletoe extract is known to induce apoptosis and immunactivation in chronic lymphocytic leukemia, and has been shown to have a non-propogating effect on leukemic cells.
Nov 01, 2007
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2007 Nov-Dec;27(6B):4195-200. PMID:
18225591
Article Published Date
: Nov 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Mistletoe
Diseases
:
Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Plant Extracts
[+]
Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.
Feb 16, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Feb 17. Epub 2015 Feb 17. PMID:
25691730
Article Published Date
: Feb 16, 2015
Study Type
: Human Study
Additional Links
Substances
:
Caffeic Acid
,
Caffeine
Diseases
:
Breast Cancer
,
Breast Cancer: Estrogen
Pharmacological Actions
:
Anti-Tumor
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
,
Estrogen Receptor Modulators
,
Insulin-Like Growth Factor Inhibition/Downregulation
Additional Keywords
:
Dose Response
,
Risk Reduction
Problem Substances
:
Tamoxifen
[+]
Molecular iodine-treated tumors exhibit less invasive potential, and significant increases in apoptosis, estrogen receptor expression, and immune cell infiltration.
Jul 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Jul 17 ;11(7). Epub 2019 Jul 17. PMID:
31319484
Article Published Date
: Jul 16, 2019
Study Type
: Human Study
Additional Links
Substances
:
Iodine
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
,
Immunomodulatory
[+]
N-acetylcysteine compares favorably to metformin on mammographic density in postmenopausal women.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Vopr Onkol. 2012 ;58(1):45-9. PMID:
22629827
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Breast: Mammographic Density
,
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Hypoglycemic Agents
Additional Keywords
:
Drug: Metformin
,
Natural Substances Versus Drugs
[+]
Puerarin: A potential therapeutic for colon adenocarcinoma patients suffering from SARS-CoV-2 infection.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:921517. Epub 2022 May 23. PMID:
35677450
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Puerarin
Diseases
:
Colon Cancer
,
Coronavirus Infection
Pharmacological Actions
:
Antioxidants
,
Antiviral Agents
,
Apoptotic
[+]
Soy isoflavones may benefit some patients with prostate cancer.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2003;47(2):111-7. PMID:
15087261
Article Published Date
: Jan 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Daidzein
,
Genistein
,
Isoflavones
,
Soy
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Suppression of pro-inflammatory and pro-survival biomarkers in oral cancer patients consuming a black raspberry phytochemical-rich troche.
Dec 22, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2015 Dec 23. Epub 2015 Dec 23. PMID:
26701664
Article Published Date
: Dec 22, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Oral Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Gene Expression Regulation
[+]
The bioactivity of garlic is multifaceted and includes activation of genes related to immunity, apoptosis, and xenobiotic metabolism in humans and Mono Mac 6 cells.
Sep 29, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Sep 30. Epub 2015 Sep 30. PMID:
26423732
Article Published Date
: Sep 29, 2015
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Leukemia: Monocytic
Pharmacological Actions
:
Apoptotic
,
Immunomodulatory
Additional Keywords
:
Gene Expression Regulation
[+]
The effect of dietary intervention with high-oleocanthal and oleacein olive oil in Patients with early-stage chronic lymphocytic leukemia.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2021 ;11:810249. Epub 2022 Jan 21. PMID:
35127522
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Oleocanthal
,
Olive leaf extract
Diseases
:
Chronic Lymphocytic Leukemia
Pharmacological Actions
:
Apoptotic
,
Chemotherapeutic
[+]
The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Cancer. 2013 ;65(2):240-6. PMID:
23441611
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, Human Study
Additional Links
Substances
:
Water: Deuterium Depleted
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Carcinoma: Small Cell Lung
,
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
Additional Keywords
:
Gene Expression Regulation
,
Proto-oncogene
[+]
The Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium.
Feb 01, 2011
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2011 Feb;93(2):267-74. Epub 2010 Dec 1. PMID:
21123460
Article Published Date
: Feb 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Atherosclerosis
,
Endothelial Dysfunction
,
Oxidative Stress
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Regenerative Actions
[+]
The present RCT provides evidence that serum from patients taking the extract showed cytotoxicity against human colorectal cancer cell lines.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asia Pac J Clin Nutr. 2017 ;26(4):606-612. PMID:
28582808
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Graviola
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Cytotoxic
[+]
These pilot data suggest that a flaxseed-supplemented, fat-restricted diet may affect prostate cancer biology and associated biomarkers.
Jun 30, 2001
Click here to read the entire abstract
Pubmed Data
: Urology. 2001 Jul ;58(1):47-52. PMID:
11445478
Article Published Date
: Jun 30, 2001
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostate Cancer
,
Testosterone: Too High
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Those with celiac disease may experience neurological damage as a result of the intolerance.
Jul 01, 2007
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2007 Jul ;133(1):195-206. Epub 2007 May 3. PMID:
17631142
Article Published Date
: Jul 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
Pharmacological Actions
:
Apoptotic
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Tomato sauce supplementation reduces prostate cancer growth in men.
Nov 01, 2002
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2002 Nov;227(10):886-93. PMID:
12424330
Article Published Date
: Nov 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Lycopene
,
Tomato
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Apoptotic
,
Chemopreventive
[+]
Treatment with melittin induces apoptosis and autophagy of fibroblastlike synoviocytes in patients with rheumatoid arthritis.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2020 ;21(8):734-740. PMID:
31820689
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Autophagy Inhibitors
,
Interleukin-1 beta downregulation
[+]
Verbena officinalis essential oil and its component citral has apoptoic-inducing activity against chronic lymphocytic leukemia.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):1097-104. PMID:
20074474
Article Published Date
: Oct 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Citral
,
Verbena officinalis
Diseases
:
Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions
:
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Vitamin E taken orally for 2 weeks before pancreatic surgery significantly induced apoptosis in the neoplastic cells of patients with pancreatic ductal neoplasia.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: EBioMedicine. 2015 Dec ;2(12):1987-95. Epub 2015 Nov 14. PMID:
26844278
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Tocotrienol: Delta
,
Vitamin E
Diseases
:
Pancreatic Cancer
,
Pancreatic Neoplasms
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
Additional Keywords
:
Significant Treatment Outcome
[+]
1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID:
22027761
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Tannic Acid
Diseases
:
Cancers
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
A cordyceps sinensis extract has a pro-apoptic effect on human lung adenocarcinoma A549 cells.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Cancer Res Ther. 2011 Oct-Dec;7(4):421-6. PMID:
22269403
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.
Mar 29, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID:
24742583
Article Published Date
: Mar 29, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Cancers: Drug Resistant
,
Pancreatic Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Cancer Stem Cells
,
Dietary Concentrations
[+]
A Nigella sativa extract showed a 88.3% inhibition of proliferation of SiHa human cervical cancer cells and increased the expression of caspase-3, -8 and -9 several-fold
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nat Prod Commun. 2013 Feb ;8(2):213-6. PMID:
23513732
Article Published Date
: Jan 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Caspase-9 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Plant Extracts
[+]
A water extract of Withania somnifera has potent cytotoxic effect on human malignant melanoma A375 cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(9):e0137498. Epub 2015 Sep 3. PMID:
26334881
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Ashwagandha
Diseases
:
Malignant Melanoma
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Alpha-bisobolol strongly induces apoptosis in glioma cells.
Mar 12, 2004
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2004 Mar 12 ;315(3):589-94. PMID:
14975741
Article Published Date
: Mar 12, 2004
Study Type
: Human In Vitro
Additional Links
Diseases
:
Glioma
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.
Jul 31, 2012
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2012 Aug 1 ;84(3):402-10. Epub 2012 Mar 29. PMID:
22483777
Article Published Date
: Jul 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Amurensin G
Diseases
:
Cancers: Drug Resistant
,
Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Cancer Stem Cells
,
Gene Expression Regulation
,
Natural Substance Synergy
[+]
An extract of Amla fruit inhibited human papillomavirus viral oncogenes responsible for development and progression of cervical cancer.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2013 ;65 Suppl 1:88-97. PMID:
23682787
Article Published Date
: Dec 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Amla Fruit
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Antiviral Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Epigenetic Modification
,
Phytotherapy
,
Plant Extracts
[+]
An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(7):e0132439. Epub 2015 Jul 15. PMID:
26176704
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Rosemary
Diseases
:
Melanoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Anti-cancer activity of bromelain nanoparticles by oral administration.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Biomed Nanotechnol. 2014 Dec ;10(12):3558-75. PMID:
26000370
Article Published Date
: Nov 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Bromelain
Diseases
:
Breast Cancer
,
Cancers: All
,
Cervical Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage associated with infertility.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 2010 Oct ;105(10):2254-61. Epub 2010 Jun 22. PMID:
20571491
Article Published Date
: Oct 01, 2010
Study Type
: Human In Vitro
Additional Links
Diseases
:
Celiac Disease
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Anti-tissue Transglutaminase Antibodies
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Immunotoxic
[+]
Anti-tumour effects of beta-sitosterol are mediated by AMPK/PTEN/HSP90 axis in AGS human gastric adenocarcinoma cells.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2018 06 ;152:60-70. Epub 2018 Mar 17. PMID:
29559312
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Beta Sitosterol
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Apoptotic
,
Heat Shock Protein Down-Regulation
[+]
Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.
Dec 25, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2022 Dec 26 ;12(1). Epub 2022 Dec 26. PMID:
36670903
Article Published Date
: Dec 25, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Arugula
,
Isothiocyanate
Diseases
:
Melanoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
Apigenin is a novel therapeutic candidate for melanoma.
Feb 13, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb 14. Epub 2017 Feb 14. PMID:
28260058
Article Published Date
: Feb 13, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Arctigenin is able to inhibit cell proliferation and may induce apoptosis and cell cycle arrest at the G0/G1 phase in glioma cells.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Feb ;13(2):1007-1013. Epub 2016 Dec 8. PMID:
28356992
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Arctigenin
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Baicalein induces caspase-dependent apoptosis in human lung carcinoma A549 cells.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2016 Mar ;77(2):73-86. Epub 2016 Mar 12. PMID:
26971531
Article Published Date
: Feb 29, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Baicalein
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Apoptotic
[+]
Berberine induced apoptosis and DNA damage in human osteosarcoma lines that were treated.
Sep 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2014 Oct ;10(4):1734-8. Epub 2014 Jul 21. PMID:
25050485
Article Published Date
: Sep 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Berberine suppressed the progression of human glioma cells.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2022 Jan-Dec;21:15347354221130303. PMID:
36255058
Article Published Date
: Dec 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Photochem Photobiol B. 2015 Jan ;142:197-203. Epub 2014 Dec 12. PMID:
25550119
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Diseases
:
Melanoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Tumor Suppressor Protein p53 Upregulation
[+]
Camel milk inhibited HepG2 and MCF7 cells survival and proliferation.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2012 ;2012:593195. Epub 2012 May 13. PMID:
22654482
Article Published Date
: Dec 31, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Camel Milk
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Capsaicin induced apoptosis in human bladder cancer cells activates dendritic cells.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2015 Apr ;31(4):578-81. Epub 2014 May 29. PMID:
25220876
Article Published Date
: Mar 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Capsaicin
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0121538. Epub 2015 May 1. PMID:
25933112
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Capsaicin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Cholangiocarcinoma
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
,
Autophagy Inhibitors
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
Chaga mushroom extract can inhibit the proliferation of tumor cells.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Int J Med Mushrooms. 2014 ;16(1):29-36. PMID:
24940902
Article Published Date
: Dec 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
Additional Keywords
:
Plant Extracts
[+]
Chrysin induces apoptosis of human uveal melanoma cells.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2016 Dec ;12(6):4813-4820. Epub 2016 Oct 13. PMID:
28105189
Article Published Date
: Nov 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Chrysin
Diseases
:
Melanoma: Uveal
Pharmacological Actions
:
Apoptotic
,
Caspase-3 Activation
,
Caspase-9 Activation
[+]
Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Cancer Res Clin Oncol. 2015 Sep ;141(9):1511-22. Epub 2014 Dec 28. PMID:
25544670
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Catechin
,
EGCG (Epigallocatechin gallate)
,
Green Tea
Diseases
:
Cancers: All
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Cancer Stem Cells
,
Natural Substance/Drug Synergy
[+]
Combined application of Grifola frondosa and vitamin C induced cell apoptosis and autophagy in vitro.
Sep 10, 2017
Click here to read the entire abstract
Pubmed Data
: Apoptosis. 2017 Sep 11. Epub 2017 Sep 11. PMID:
28894987
Article Published Date
: Sep 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Maitake Mushroom
,
Vitamin C
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
Additional Keywords
:
Polysaccharides
[+]
Cucurbitacin B in the combination with curcumin could serve as a novel, promising approach for human hepatoma.
Oct 05, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Oct 6. Epub 2015 Oct 6. PMID:
26452516
Article Published Date
: Oct 05, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Cucurbitacin B
,
Curcumin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Multidrug Resistance
,
Natural Substance Synergy
[+]
Cucurmosin has potential anticancer activity for human hepatoma.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2012 Jan ;5(1):196-201. Epub 2011 Sep 30. PMID:
21964700
Article Published Date
: Dec 31, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Pumpkin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Breast Cancer. 2015 Sep ;18(3):225-34. Epub 2015 Sep 24. PMID:
26472972
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Citral
,
Curcumin
,
Lemongrass
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Dose Response
,
Natural Substance Synergy
,
Selective Cytotoxicity
[+]
Curcumin inhibited proliferation and induced apoptosis in both KG-1 and U937 cells.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Hematol Oncol Stem Cell Res. 2016 Jul 1 ;10(3):120-9. PMID:
27489587
Article Published Date
: Jun 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Acute Myeloid Leukemia
,
Acute Myeloid Leukemia: Stem Cell
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Cancer Stem Cells
[+]
Curcumin treatment causes a rapid increase in reactive oxygen species and a decrease in the mitochondrial membrane potential-events leading to apoptosis activation.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2014 Dec ;48(12):1397-408. Epub 2014 Oct 6. PMID:
25179440
Article Published Date
: Nov 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Heat Shock Protein Inducer
[+]
Dandelion root induces selective apoptosis and autophagy in human pancreatic cancer cells in a dose and time dependent manner.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Pancreas. 2012 Oct ;41(7):1039-47. PMID:
22647733
Article Published Date
: Sep 30, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Dandelion
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
Additional Keywords
:
Selective Cytotoxicity
[+]
Delta tocotrienol might represent an effective option for chemopreventive strategies for melanoma.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:30502. Epub 2016 Jul 27. PMID:
27461002
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Tocotrienol: Delta
Diseases
:
Melanoma
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
[+]
Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Radiat Res. 2008 Sep ;170(3):327-34. PMID:
18763855
Article Published Date
: Sep 01, 2008
Study Type
: Human In Vitro
Additional Links
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Apoptotic
[+]
Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Radiat Res. 2008 Sep ;170(3):327-34. PMID:
18763855
Article Published Date
: Sep 01, 2008
Study Type
: Human In Vitro
Additional Links
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Apoptotic
[+]
Electromagnetic fields induce astrocytoma proliferation in vitro.
Jan 12, 2009
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 2009 12 ;24(12):1551-61. PMID:
19795354
Article Published Date
: Jan 12, 2009
Study Type
: Human In Vitro
Additional Links
Diseases
:
Astrocytoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Heat Shock Protein Inducer
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Emodin induces apoptosis and autophagy of fibroblasts obtained from patient with ankylosing spondylitis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2019 ;13:601-609. Epub 2019 Feb 11. PMID:
30809091
Article Published Date
: Dec 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Emodin
Diseases
:
Spondylitis: Ankylosing
Pharmacological Actions
:
Apoptotic
[+]
Extracts of T. sinensis inhibited cell proliferation and induced apoptosis in human leukemia HL-60 cells.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem Lett. 2014 Sep 1 ;24(17):4286-90. Epub 2014 Jul 14. PMID:
25074815
Article Published Date
: Aug 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Toona sinensis
Diseases
:
Leukemia
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Fenugreek extract can significantly enhance radiation induced apoptosis.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Signals Sens. 2015 Jul-Sep;5(3):176-81. PMID:
26284174
Article Published Date
: Jun 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Fenugreek
Diseases
:
Cancers: All
Pharmacological Actions
:
Apoptotic
,
Radiosensitizer
Additional Keywords
:
Plant Extracts
[+]
Fermented brown rice extract causes apoptotic death of human acute lymphoblastic leukemia cells.
Jan 13, 2016
Click here to read the entire abstract
Pubmed Data
: Appl Biochem Biotechnol. 2016 Jan 14. Epub 2016 Jan 14. PMID:
26769704
Article Published Date
: Jan 13, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Brown Rice
,
Fermented Foods and Beverages
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2016 Oct ;41(10):2728-2751. Epub 2016 Jul 9. PMID:
27394418
Article Published Date
: Sep 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
Gamma- tocopherol was superior to alpha- tocopherol in the inactivation of the Kinase Akt.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Signal. 2013 ;6(267):ra19. Epub 2013 Mar 19. PMID:
23512990
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Vitamin E
,
Vitamin E: Gamma-Tocopherol
Diseases
:
Cancer: Prostate
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Enzyme Inhibitors
Additional Keywords
:
Akt Inhibition
[+]
Genetic polymorphisms affect superoxide dismutase activity may potentiate the negative effects of magnetic fields.
Feb 01, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2017 Feb ;24(5):5078-5088. Epub 2016 Dec 21. PMID:
28004364
Article Published Date
: Feb 01, 2017
Study Type
: Human In Vitro
Additional Links
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Goji berry extracts have chemopreventive potential in breast cancer treatment.
Nov 01, 2015
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2015 Nov 2:1-4. Epub 2015 Nov 2. PMID:
26525080
Article Published Date
: Nov 01, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Goji
Diseases
:
Breast Cancer
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
Additional Keywords
:
Dose Response
,
Plant Extracts
,
Selective Cytotoxicity
[+]
Graviola extracts inhibited the proliferation of HL-60 cells in a concentration dependent manner and induced apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2014 ;14(1):516. Epub 2014 Dec 24. PMID:
25539720
Article Published Date
: Dec 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Graviola
Diseases
:
Acute Myeloid Leukemia
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Honokiol has a unique application in chemotherapy for human thyroid cancers.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Jan ;115:288-298. Epub 2016 Dec 7. PMID:
27940017
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Honokiol
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
Honokiol induced apoptosis and autophagy in glioblastoma multiforme cells.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Data Brief. 2016 Dec ;9:667-672. Epub 2016 Oct 8. PMID:
27774504
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Honokiol
Diseases
:
Glioma
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
[+]
Human bladder cancer cells and immortalized normal bladder cells were studied using Frankincense oil; Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability.
Dec 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2009 ;9:6. Epub 2009 Mar 18. PMID:
19296830
Article Published Date
: Dec 31, 2008
Study Type
: Human In Vitro
Additional Links
Substances
:
Frankincense
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
,
Selective Cytotoxicity
[+]
Human NB SH-SY5Y cells undergo apoptosis in response to treatment with cucurbitacin B.
Jun 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2014 Jul ;10(1):89-94. Epub 2014 Apr 24. PMID:
24789581
Article Published Date
: Jun 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Irradiation with blue LED light induced apoptotic cell death through autophagosome activation in RAMOS cells.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Data Brief. 2016 Mar ;6:630-3. Epub 2016 Jan 15. PMID:
26909378
Article Published Date
: Feb 29, 2016
Study Type
: Human In Vitro
Additional Links
Diseases
:
Lymphoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Apoptotic
[+]
Isoliquiritigenin is a candidate agent for the treatment of human ovarian cancer.
Sep 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Sep 21 ;18(10). Epub 2017 Sep 21. PMID:
28934130
Article Published Date
: Sep 20, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Autophagy Up-regulation
[+]
Kahweol inhibits colorectal tumor cell growth by promoting apoptosis and suppressing HSP70 expression.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2015 Mar ;23(2):128-33. Epub 2015 Mar 1. PMID:
25767680
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Kahweol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Caspase-3 Activation
,
Heat Shock Protein Down-Regulation
[+]
Lyophilised camel's milk triggered apoptosis in BT-474 human breast cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2015 ;16(15):6651-61. PMID:
26434890
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Camel Milk
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
M. nigra may be a novel candidate for the development of new natural product based therapeutic agents against prostate cancer.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi Pharm J. 2017 Feb ;25(2):241-248. Epub 2016 Jun 20. PMID:
28344475
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mulberry
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Magnetic fields may upregulate chemoresistance in human glioblastoma.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Electromagn Biol Med. 2018 ;37(3):138-145. Epub 2018 May 30. PMID:
29846098
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Diseases
:
Glioblastoma
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Chemoresistance upregulation
[+]
Magnolol induced cell cycle arrest and promoted apoptosis in gallbladder carcinoma cells by regulating the p53 signaling pathway.
Sep 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Sci. 2015 Oct ;106(10):1341-50. PMID:
26250568
Article Published Date
: Sep 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Magnolol
Diseases
:
Gallbladder Cancer
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Cyclin D1 Down-Regulation
,
P21 Activation
,
Tumor Suppressor Protein p53 Upregulation
[+]
Makgeolli reduced the tumor size and volume in gastric adenocarcinoma tumor xenografts.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microbiol Biotechnol. 2015 Sep ;25(9):1485-92. PMID:
26017227
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Rice
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
Melatonin as a novel selective ATF-6 inhibitor can sensitize human hepatoma cells to ER stress inducing apoptosis.
Feb 13, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2017 Feb 14 ;23(6):986-998. PMID:
28246472
Article Published Date
: Feb 13, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
Cyclooxygenase 2 Inhibitors
[+]
Melatonin in combination with HDAC inhibitors may be a novel therapeutic intervention for human lung adenocarcinoma.
Jul 15, 2015
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2015 Jul 16. Epub 2015 Jul 16. PMID:
26184924
Article Published Date
: Jul 15, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human liver cancer cells.
Feb 07, 2017
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2017 Feb 8. Epub 2017 Feb 8. PMID:
28178378
Article Published Date
: Feb 07, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: Sorafenib
,
Dose Response
[+]
Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.
Mar 30, 2016
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2016 Mar 31 ;62(3):72-7. Epub 2016 Mar 31. PMID:
27064876
Article Published Date
: Mar 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
White Mulberry
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
,
COLON CANCER
,
Dose Response
,
Plant Extracts
,
White Mulberry
[+]
Naringenin causes ASK1-induced apoptosis via reactive oxygen species in human pancreatic cancer cells.
Nov 08, 2016
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2016 Nov 9. Epub 2016 Aug 9. PMID:
27838343
Article Published Date
: Nov 08, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Naringenin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Neem leaf extract exhibits anti-leukemic properties in patient primary chronic lymphocytic leukemia cells.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Leuk Lymphoma. 2014 Mar ;55(3):652-61. Epub 2013 Jul 1. PMID:
23721511
Article Published Date
: Feb 28, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Neem
Diseases
:
Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Nigella sativa has successfully produced inhibition of growth of MCF cell lines with an equivalent potency as that of the standard cisplatin.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacognosy Res. 2015 Apr-Jun;7(2):193-7. PMID:
25829794
Article Published Date
: Mar 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Natural Substances Versus Drugs
,
Superiority of Natural Substances versus Drugs
[+]
P. granatum extracts had cytotoxic and apoptotic effects on human U266 multiple myeloma cells via disruption of mitochondrial membrane potential and increasing cell cycle arrest.
Aug 28, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Aug 29. Epub 2015 Aug 29. PMID:
26318303
Article Published Date
: Aug 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Multiple Myeloma
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
,
Cytotoxic
Additional Keywords
:
Plant Extracts
[+]
P. sulcata inhibited the growth in a dose-dependent manner and induced caspase-independent apoptosis at low doses.
Apr 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cytotechnology. 2015 May ;67(3):531-43. Epub 2014 Mar 28. PMID:
24676908
Article Published Date
: Apr 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Lichens
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
,
Caspase-3 Activation
Additional Keywords
:
Apoptotic
,
Breast Cancer
,
Breast Cancer: Triple Negative
,
Caspase-3 Activation
,
Dose Response
,
Lichens
[+]
Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.
May 08, 2012
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2012 May 8. Epub 2012 May 8. PMID:
22566066
Article Published Date
: May 08, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Catechin
,
EGCG (Epigallocatechin gallate)
,
Ginseng
,
Green Tea
,
Panaxadiol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Natural Substance Synergy
[+]
Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intest Res. 2017 Apr ;15(2):174-181. Epub 2017 Apr 27. PMID:
28522946
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Feverfew
,
Parthenolide
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Parthenolide is a strong apoptotic inducer that deserves the further investigations for potential chemotherapeutic agent of human oral cancers.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oral Oncol. 2015 Jun ;51(6):602-9. Epub 2015 Mar 26. PMID:
25817195
Article Published Date
: May 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Parthenolide
Diseases
:
Oral Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
[+]
Piperine was found to exert selective cytotoxic effects against A549 cells in a dose-dependent manner.
Mar 31, 2014
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2014 Apr ;35(4):3305-10. Epub 2013 Nov 24. PMID:
24272201
Article Published Date
: Mar 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Piperine
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
Bax/Bcl2 ratio: Increase
,
Bcl-2 protein down-regulation
,
Caspase-3 Activation
,
Caspase-9 Activation
,
Cell cycle arrest
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Selective Cytotoxicity
[+]
Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2016 ;11:4991-5002. Epub 2016 Aug 3. PMID:
27757032
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Myricetin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Apoptotic
,
Cytotoxic
,
MicroRNA modulator
[+]
Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.
Apr 15, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID:
21496306
Article Published Date
: Apr 15, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Fermented Foods and Beverages
,
Wheat Germ
Diseases
:
Cancers
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Chemotherapeutic Synergy: Oxaliplatin
,
Plant Extracts
[+]
Psoralea corylifolia induces apoptosis and autophagy and alteres genes expression assayed by cDNA microarray in human prostate cancer PC-3 cells.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2018 Jul ;33(7):770-788. Epub 2018 Apr 18. PMID:
29667321
Article Published Date
: Jun 30, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Babchi
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
[+]
Resveratrol can be considered as a neo-adjuvant to improve sorafenib efficacy in breast cancer treatment.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Dec ;84:1906-1914. Epub 2016 Nov 15. PMID:
27863838
Article Published Date
: Nov 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Breast Cancer
Pharmacological Actions
:
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Chemothapeutic Synergy: Sorafenib
[+]
Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.
Dec 14, 2016
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2016 Dec 15. Epub 2016 Dec 15. PMID:
28000876
Article Published Date
: Dec 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
MicroRNA modulator
[+]
Resveratrol may represent a new interesting therapeutic approach, in order to affect glioma stem cell proliferation and motility.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(1):e0169854. Epub 2017 Jan 12. PMID:
28081224
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Glioblastoma Multiforme
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Cancer Stem Cells
[+]
Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer.
Jan 29, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2017 Jan 30. Epub 2017 Jan 30. PMID:
28197628
Article Published Date
: Jan 29, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Cancers: Drug Resistant
,
Oral Cancer
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
[+]
Sanguinarine induces apoptosis of human oral squamous cell carcinoma KB cells.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2016 Aug ;77(5):227-40. Epub 2016 Jul 1. PMID:
27363951
Article Published Date
: Jul 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Bloodroot
Diseases
:
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-9 Activation
[+]
Saponin extracts induced apoptosis of endometrial cells from women with endometriosis.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Reprod Sci. 2017 Jan 1:1933719117711263. Epub 2017 Jan 1. PMID:
28558522
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng (Siberian)
Diseases
:
Endometriosis
Pharmacological Actions
:
Apoptotic
,
MicroRNA modulator
Additional Keywords
:
Plant Extracts
[+]
Sea buckthorn procyanidins were promising FAS inhibitors which could induce the apoptosis of MDA-MB-231 cells.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2014 Oct ;35(10):9563-9. Epub 2014 Jun 24. PMID:
24957042
Article Published Date
: Sep 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Sea buckthorn
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Dose Response
,
Phytotherapy
[+]
Shikonin induces apoptosis in HL-60 cells without significant effect on primary cells from healthy volunteers.
Jul 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2016 Jul 15 ;39(2):604-616. Epub 2016 Jul 15. PMID:
27415599
Article Published Date
: Jul 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Shikonin
Diseases
:
Acute Myeloid Leukemia
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Dose Response
[+]
Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Expert Opin Ther Targets. 2016 Jan ;20(1):7-18. Epub 2015 Dec 15. PMID:
26568207
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK
,
Anti-metastatic
,
Apoptotic
,
Chemosensitizer
[+]
Spirulina phycocyanin induces differential protein expression and apoptosis in SKOV-3 cells.
Sep 25, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2015 Sep 26 ;81:951-959. Epub 2015 Sep 26. PMID:
26410814
Article Published Date
: Sep 25, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Spirulina
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Apoptotic
[+]
Strawberry can be developed as therapeutic or preventive agent for uterine leiomyomas.
Feb 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Feb 15. Epub 2017 Feb 15. PMID:
28212568
Article Published Date
: Feb 14, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Anthocyanins
,
Strawberry
Diseases
:
Leiomyoma
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Plant Extracts
[+]
Sulforaphane attentuates cadmium-induced carcinogenesis through Nrf2, antioxidant, and autophagy mechanisms.
Jan 15, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2018 08 15 ;353:23-30. Epub 2018 Jun 6. PMID:
29885333
Article Published Date
: Jan 15, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Cadmium Poisoning
,
Cancers
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidant
,
Antioxidant Effects
,
Apoptotic
,
Autophagy Up-regulation
,
NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Sulforaphane inhibits Wnt/β-catenin signaling in colorectal cancer cells, supressing proliferation and inducing cell death.
Sep 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2018 Sep 21 ;9(74):33982-33994. Epub 2018 Sep 21. PMID:
30338040
Article Published Date
: Sep 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Anti-cancer
[+]
Sulforaphane suppresses proliferation and enhances apoptosis of gastric cancer stem cells in vitro.
Aug 01, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2019 Aug ;70(5):570-578. Epub 2019 Jan 9. PMID:
30624124
Article Published Date
: Aug 01, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Gastric Cancer
,
Gastric Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Anti-cancer
[+]
Sulforaphene inhibits liver cancer cell proliferation by stimulating apoptosis and causing cytotoxicity.
Jun 04, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jun 4 ;10(6). Epub 2018 Jun 4. PMID:
29866995
Article Published Date
: Jun 04, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Tetrahydrocurcumin exhibited significant cell growth inhibition by inducing MCF-7 cells to undergo mitochondrial apoptosis and G2/M arrest.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 May ;67:193-200. Epub 2014 Mar 1. PMID:
24593988
Article Published Date
: Apr 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin: Degradiation byproducts
,
Tetrahydrocurcumin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Caspase-3 Activation
,
Cell cycle arrest
,
P21 Activation
[+]
THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells.
Apr 30, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Invest. 2010 May ;28(4):357-63. PMID:
19916793.
Article Published Date
: Apr 30, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
The annatto constituent cis-bixin has intriguing selective anti-myeloma activity.
Sep 30, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxid Redox Signal. 2010 Oct 1 ;13(7):987-97. PMID:
20170403
Article Published Date
: Sep 30, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Achiote
,
NAC (N-acetyl-L-cysteine)
Diseases
:
Cancers: Multi-Drug Resistant
,
Multiple Myeloma
,
Oxidative Stress
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
Additional Keywords
:
Natural Substance Synergy
,
Phytotherapy
,
Plant Extracts
,
Selective Cytotoxicity
[+]
The anti-cancer effect of four curcumin analogues on human glioma cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2021 ;14:4345-4359. Epub 2021 Aug 4. PMID:
34376999
Article Published Date
: Dec 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Bisdemethoxycurcumin
,
Curcumin
,
Curcuminoids
,
Demethoxycurcumin
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
The present data suggest that targeting CB(1)/CB(2) may have therapeutic potential for the treatment of mantle cell lymphoma.
Oct 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Pharmacol. 2006 Nov ;70(5):1612-20. Epub 2006 Aug 25. PMID:
16936228
Article Published Date
: Oct 31, 2006
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabinoids
,
Cannabinoids: Synthetic
Diseases
:
Lymphoma
Pharmacological Actions
:
Apoptotic
,
P38 Mitogen-Activated Protein Kinase Modulator
Additional Keywords
:
Selective Cytotoxicity
[+]
The present study results indicated that human bladder cancer T-24 cells are highly sensitive to growth inhibition by apigenin.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell Int. 2015 ;15:33. Epub 2015 Mar 29. PMID:
25859163
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Bladder Cancer
,
Bladder Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Cell cycle arrest
,
P21 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Dose Response
[+]
The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2015;2015:154164. Epub 2015 Jun 9. PMID:
26180579
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Black Currant
,
Blackberry
,
Blueberry
,
Cranberry
,
Indian Gooseberry
,
Lingonberry
,
Raspberry
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Apoptotic
,
Caspase-8 activation
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
,
Growing Your Own Food
,
Procyanidins
[+]
The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.
Mar 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell. 2006 Apr ;9(4):301-12. PMID:
16616335
Article Published Date
: Mar 31, 2006
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Cannabinoids
Diseases
:
Astrocytoma
,
Cancers: All
,
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
