Apoptotic

Name	AC	CK
Curcumin	477	595
Resveratrol	161	196
Ginsenosides	138	160
Sulforaphane	95	157
Flavonoids	124	144
EGCG (Epigallocatechin gallate)	79	120
Thymoquinone	79	104
Quercetin	84	93
Vitamin C	63	88
Tanshinone IIA	75	83
Genistein	63	79
Berberine	62	72
Oridonin	59	69
Polyphenols	56	68
Licorice	59	67
Melatonin	46	67
Apigenin	45	65
Cannabinoids	47	64
Shikonin	50	64
Luteolin	56	63
Fucoidan	56	62
Silibinin	41	62
Honokiol	43	61
Cucurbitacin B	41	58
Indole-3-Carbinol	40	55
Catechin	38	54
Beta-Elemene	48	52
Pterostilbene	43	49
Ursolic Acid	37	47
Garlic	34	46
Xanthohumol	40	46
Betulinic acid	39	45
Myricetin	37	45
Capsaicin	15	44
Parthenolide	32	44
Cannabidiol	35	43
Delta-tetrahydrocannabinol (THC)	27	42
Deguelin	33	41
Fisetin	37	41
Green Tea	25	41
Wogonin	28	40
Grape Seed Extract	23	39
Reishi Mushroom	29	39
Emodin	30	38
Astaxanthin	22	37
Chrysin	28	37
Isoflavones	21	37
Piperlongumine	27	37
Vitamin E	22	37
Isoliquiritigenin	27	36
Ginger	27	35
Bee Venom	20	33
Anthocyanins	21	32
Fermented Foods and Beverages	19	31
Baicalein	23	30
Ellagic Acid	23	30
Moringa oleifera	24	30
Mulberry	20	29
NAC (N-acetyl-L-cysteine)	11	29
Turmeric	24	29
Bufalin	25	28
Phellinus Linteus	23	28
Vitamin D	26	28
Cannabinoids: Synthetic	16	27
Nigella sativa (aka Black Seed)	19	27
Artemisinin	23	26
Gingerol	20	26
Huaier (Trametes robiniophila murr)	22	26
Piperine	19	26
Ashwagandha	18	25
Formononetin	19	25
Frankincense	13	25
Kaempferol	23	25
Lichens	20	25
Lotus	23	25
Magnolol	17	25
Paeonol	20	25
Lycopene	14	24
Mistletoe	12	24
Tocotrienol: Delta	10	24
6-Shogaol	20	23
Daidzein	10	23
Graviola	8	23
Isothiocyanates	20	23
Lactoferrin	21	23
Naringenin	18	23
Paeoniflorin	19	23
Stilbenes	20	23
Fucoxanthin	16	22
Puerarin	19	22
Piceatannol	20	21
Arctigenin	14	20
Bromelain	12	20
Carnosic Acid	15	20
Citral	6	20
Cordyceps Militaris	19	20
Crocin	17	20
Curcumol	16	20
Diosgenin	18	20
Flaxseed	9	20
Ginkgo biloba	15	20
Milk Thistle	8	20
Tomato	7	20
Angelica	7	19
Blueberry	11	19
Chaga Mushroom (Inonotus obliquus)	12	19
Homeopathic Medicine: All	15	19
Maitake Mushroom	11	19
Raspberry	13	19
Toona sinensis	11	19
Allicin	17	18
Artesunate	16	18
Asiatic Acid	15	18
Gallic Acid	16	18
Peony	16	18
Pomegranate	11	18
Caffeic Acid	7	17
Dandelion	11	17
Demethoxycurcumin	14	17
Nobiletin	15	17
Phloretin	16	17
Spirulina	9	17
Tetrahydrocurcumin	10	17
Zerumbone	13	17
Bee Propolis	15	16
DHA (Docosahexaenoic Acid)	13	16
Gold (nanoparticles)	15	16
Neem	11	16
Benzyl isothiocyanate	13	15
Cannabis	14	15
Carotenoids	5	15
Cruciferous Vegetables	10	15
EPA (Eicosapentaenoic Acid)	4	15
Mangosteen	8	15
Medicinal Mushrooms	12	15
Oleuropein	14	15
Aloe Vera	12	14
Black Tea	10	14
Cinnamon	11	14
Ginseng	8	14
Iodine	4	14
Mushrooms: All	8	14
Selenium	12	14
Water: Deuterium Depleted	4	14
Wheat Germ	9	14
Astragaloside	12	13
Berbamine	12	13
Bisdemethoxycurcumin	11	13
Black Raspberry	4	13
Caffeine	3	13
Camel Milk	4	13
Chinese Skullcap	11	13
Citrus naringin	10	13
Cranberry	9	13
Feverfew	9	13
Kahweol	9	13
Oleanolic acid	11	13
Phenethyl isothiocyanate	10	13
Prunella vulgaris	9	13
Pycnogenol (Pine Bark)	4	13
Rhubarb	9	13
Soy	3	13
Zinc	8	13
Beta Sitosterol	8	12
Biochanin A	11	12
Caffeic acid phenethyl ester	11	12
Carrot	7	12
Cryptoxanthin	3	12
Fenugreek	7	12
Goji	8	12
Hesperidin	10	12
Manuka Honey	7	12
Rose	11	12
Silver (nanoparticles)	11	12
Tangeretin	11	12
Tocotrienol: Gamma	8	12
Vitamin C: Intravenous	4	12
Vitamin E: Gamma-tocotrienol	12	12
Anandamide	9	11
Broccoli	9	11
Celastrol	9	11
Ginseng (Korean)	8	11
Lupeol	9	11
Mangiferin	10	11
Nettle	10	11
Rosemary	7	11
Shiitake Mushroom	7	11
Strawberry	6	11
Vitamin K	10	11
Walnut	11	11
Amygdalin	8	10
Apples	8	10
Babchi	6	10
Bai Zhu	8	10
Blackberry	5	10
Burdock	9	10
Carnosol	9	10
Carvacrol	8	10
Cucurbitacin E	9	10
Curcuminoids	9	10
Eugenol	9	10
Fiber	7	10
Grape	8	10
Kefir	7	10
Lemongrass	4	10
MSM (Methylsulfonylmethane)	7	10
Motherwort	1	10
Olive leaf extract	6	10
Omega-3 Fatty Acids	7	10
Psychedelics:All	9	10
Rutin	8	10
Sesamin	8	10
Sesamol	8	10
Silymarin	8	10
Verbena officinalis	1	10
Wormwood	9	10
Bitter Melon	9	9
Black Pepper	5	9
Bloodroot	5	9
Chlorogenic Acid	9	9
Cinnamaldehyde	7	9
Citrus Peel	7	9
Cucurbitacin D	8	9
Eucalyptus	7	9
Lion's Mane (Hericium Erinaceus)	8	9
Nexrutine (Phellodendrom)	7	9
Orange	7	9
Probiotics	6	9
Red Sage	8	9
Rosemaric Acid	9	9
Sweet Potato: Purple	7	9
Theaflavins	9	9
Tualang Honey	4	9
Vitexins	7	9
Wheat Grass	7	9
Amla Fruit	3	8
Antrodia camphorata	6	8
Avocado	4	8
D-Limonene	7	8
Diosmetin	8	8
Diosmin	6	8
Fig	7	8
Garcinia Mangostana	4	8
Genipin	6	8
Ginseng (Siberian)	4	8
Gynostemma	8	8
Holy Basil	7	8
Honey	7	8
Lignans	6	8
Modified Arabinoxylan Rice Bran (MGN-3)	5	8
Prickly Pear Cactus	7	8
Pumpkin	3	8
Shallot	7	8
Soy Protein	4	8
Tannic Acid	4	8
Verbascoside	5	8
Vitamin E: alpha tocopherol	6	8
Whey	5	8
White Mulberry	4	8
Agaricus Blazei	5	7
Beet	6	7
Bergamot	3	7
Butyrate	7	7
Crocetin	6	7
Curry Leaves	5	7
Delphinidin	7	7
Dogwood	3	7
Fish Oil	4	7
Inositol Hexaphosphate	5	7
Lactobacillus casei	6	7
Lemon	5	7
Lithospermum erythrorhizon	6	7
Nordihydroguaiaretic acid (NDGA)	6	7
Phyllanthus urinaria	7	7
Piperidines	5	7
Safflower	6	7
Saffron	6	7
Sea buckthorn	3	7
Sophora Flavescens	5	7
Soursop	5	7
St. Johns Wort	6	7
Syrian rue	6	7
Tripterygium wilfordii	6	7
Bacopa	5	6
Bamboo	5	6
Bay leaf	6	6
Brown Rice	2	6
Cardamonin	6	6
Cocoa	5	6
Curcumin: Degradiation byproducts	2	6
Endocannabinoids	5	6
Evodiamine	5	6
Fennel	5	6
Indian Gooseberry	2	6
Jujube	5	6
Long Pepper	4	6
Noni	6	6
Oregano	5	6
Panax Ginseng	5	6
Pine Bark Extract	6	6
Polyunsaturated Fatty Acids (PUFAs)	4	6
Proanthocyanidins	5	6
Punicalagin	6	6
Red Clover	5	6
Rosmarinic acid	4	6
Solanum nigrum (black nightshade)	5	6
Sprouts	5	6
Sweet Potato	4	6
Tea	5	6
Vitamin E: Gamma-Tocopherol	2	6
Vitamin K2	5	6
Zyflamend	6	6
beta-Carotene	6	6
Achiote	1	5
Adlay	5	5
Amurensin G	1	5
Andrographis	5	5
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	2	5
Apple Polyphenols	5	5
Barley	3	5
Black Currant	1	5
Broccoli Sprouts	3	5
Cafestol	5	5
Chlorella (Algae)	3	5
Cordyceps sinensis	5	5
Cyanidin 3-glucoside	4	5
Daisy	4	5
Damnacanthal	5	5
Echinacea	4	5
Eriodictyol	4	5
False Black Pepper	5	5
Geranium	3	5
Hawthorn	5	5
Honeysuckle	5	5
Hops	5	5
Hydroxytyrosol	5	5
Ligustrazine	4	5
Lingonberry	1	5
Liquiritigenin	3	5
Litchi	4	5
Nicotinamide adenine dinucleotide (NADH)	3	5
Olive	4	5
Palash	4	5
Panax Notoginseng	5	5
Panaxadiol	1	5
Patchouli	3	5
Pineapple	3	5
Rice	1	5
Sandalwood	5	5
Thymol	5	5
Tocotrienols	4	5
Triptolide	5	5
White Tea	4	5
18β-Glycyrrhetinic Acid	3	4
Alpha-Lipoic Acid	4	4
Alpinia galanga	3	4
Apple	3	4
Astragalus	4	4
Banana	3	4
Bergamot orange	4	4
Boswellia	3	4
CLA (Conjugated Linoleic Acid)	3	4
Chokeberry	4	4
Chrysanthemum Indicum	4	4
Corn Silk	4	4
Coumestrol	4	4
Diallyl sulfide	3	4
Essential Oils: Unspecified	3	4
Ferulic acid	4	4
Gac	3	4
Galbanic Acid	4	4
Geraniol	4	4
Gleditsia sinensis	3	4
Helenalin	4	4
Hibiscus	4	4
Hibiscus sabdariffa	3	4
Hyperforin	4	4
Isoquercitrin	3	4
Japanese mugwort	4	4
Juniper	3	4
Kava Kava	3	4
Kiwifruit	3	4
Lactobacillus Acidophilus	3	4
Lactobacillus paracasei	4	4
Lactobacillus plantarum	4	4
Lutein	4	4
Magnolia	3	4
Marijuana	4	4
Marjoram	4	4
Oyster Mushroom	4	4
Perilla	4	4
Persimmon	4	4
Phyllanthus amarus	4	4
Pleurotus nebrodensis	3	4
Red Wine Extract	4	4
S-Adenosylmethionine (SAMe)	3	4
Sea Cucumber	2	4
Seaweed: Brown	4	4
Shemamruthaa	2	4
Sumac	4	4
Tabebuia	4	4
Thyme	3	4
Trichosanthes Kirilowii	3	4
Vanillin	3	4
Vitamin E: delta-tocopherol	3	4
Wasabi	3	4
Xanthones	4	4
Yerba Santa	2	4
Amygdalin (laetrile)	3	3
Apple Pectin	2	3
Arginine	2	3
Beans: All	3	3
Berries: All	3	3
Beta-Caryophyllene	3	3
Betaine	2	3
Bilberry	2	3
Bile salts	2	3
Bitter Orange	3	3
Buckwheat	2	3
Camptothecin	2	3
Chlorophyllin	2	3
Coffee	3	3
Collagen	2	3
Colloidal Silver	3	3
Cyanidin	3	3
Dibenzoylmethane (DBM)	2	3
Dill	3	3
Dimethyl trisulfide (DMTS)	2	3
False Daisy	2	3
Folate	3	3
Folic Acid	2	3
Garlic: Aged	3	3
Ginseng (American)	3	3
Ginseng, unspecified species	3	3
Harmine	3	3
Insulin-like Growth Factor (IGF-1)	2	3
Lactobacillus rhamnosus	2	3
Lactobacillus rhamnosus GG	3	3
Lysine	3	3
Modified Citrus Pectin	2	3
Mugwort	3	3
Oak	3	3
Okra	3	3
Oleocanthal	3	3
Olive Oil	3	3
P-Coumaric Acid	3	3
Palm Oil	2	3
Passion Flower	2	3
Pea	2	3
Peanut	2	3
Perillaldehyde	2	3
Phyllanthus emblica	3	3
Phyllanthus niruri (Stonebreaker)	3	3
Physalis minima	3	3
Pine Needle	2	3
Plum	3	3
Pomegranate Peel	3	3
Procyanidin B2	3	3
Red Yeast Rice	2	3
Riboflavin (Vitamin B-2)	3	3
Ruta Graveolens	3	3
Sage	3	3
Seaweed	2	3
Spinach	2	3
Theanine	2	3
Thistle	3	3
Tongkat Ali	3	3
Traditional Chinese Medicine: Mylabris	2	3
Turmerones	3	3
Urolithin A	3	3
Venom: Toad	2	3
Vitamin A	3	3
Wheat Bran	2	3
White Button Mushroom	2	3
Zeaxanthin	2	3
acetyl-11-keto-beta-boswellic acid	3	3
phytoestrogens	2	3
Allspice	1	2
Andrographolide	2	2
Anthurium schlechtendalii	1	2
Antioxidant formulas	1	2
Arachidonyl Ethanolamide (AEA)	2	2
Arugula	1	2
Asparagus	2	2
Azelaic Acid	1	2
Banaba	2	2
Barberry	2	2
Bifidobacterium Longum	1	2
Bifidobacterium animalis	1	2
Black Cohosh	2	2
Brown Rice: Pre-Germinated	1	2
Calcium	1	2
Cannabigerol	1	2
Capparis spinosa (caper)	2	2
Cashew	1	2
Catechols	2	2
Chamomile	2	2
Cinnamic acid	1	2
Clove	2	2
Coenzyme Q10	1	2

[+]

Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells.May 28, 2022

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Pubmed Data : Nutr Res. 2022 May 29 ;105:33-52. Epub 2022 May 29. PMID: 35797732

Article Published Date : May 28, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Naringenin

Diseases : Cancers: All

Pharmacological Actions : Apoptotic

[+]

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID: 29040973

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID: 26023082

Article Published Date : Sep 30, 2015

Study Type : Animal Study, Human Study, In Vitro Study

Additional Links

Substances : Cryptoxanthin

Diseases : Colon Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin

[+]

Chinese motherwort has cytotoxicity against human breast cancer cells that is non-apoptic and estrogen receptor independent. Mar 18, 2009

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Pubmed Data : J Ethnopharmacol. 2009 Mar 18;122(2):234-9. PMID: 19330917

Click here to read the entire abstract

Pubmed Data : Nutrition. 2005 Oct;21(10):1010-7. PMID: 16157238

Article Published Date : Oct 01, 2005

Study Type : Human Study

Additional Links

Substances : EPA (Eicosapentaenoic Acid)

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic

[+]

Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients.Jun 17, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2022 Jun 18 ;12(1):10303. Epub 2022 Jun 18. PMID: 35717540

Article Published Date : Jun 17, 2022

Study Type : Human Study

Additional Links

Substances : Genistein, Progesterone

Diseases : Endometrial Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Grape seed procyanidin extract mediates antineoplastic effects against lung cancer.Nov 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Prev Res (Phila). 2016 Dec ;9(12):925-932. Epub 2016 Sep 22. PMID: 27658889

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Grape Seed Extract

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Proanthocyanidins

[+]

Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.Jan 01, 2000

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Pubmed Data : Jpn J Cancer Res. 2000 Jan;91(1):34-40. PMID: 10744042

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Diseases : Adult T-cell leukemia/lymphoma (ATL)

Pharmacological Actions : Anticarcinogenic Agents, Antiviral Agents, Apoptotic

[+]

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

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The Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium.Feb 01, 2011

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Pubmed Data : Am J Clin Nutr. 2011 Feb;93(2):267-74. Epub 2010 Dec 1. PMID: 21123460

Article Published Date : Feb 01, 2011

Study Type : Human Study

Additional Links

Diseases : Atherosclerosis, Endothelial Dysfunction, Oxidative Stress

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Apoptotic

Additional Keywords : Regenerative Actions

[+]

The present RCT provides evidence that serum from patients taking the extract showed cytotoxicity against human colorectal cancer cell lines. Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID: 22027761

Article Published Date : Oct 01, 2011

Study Type : Human In Vitro

Additional Links

Substances : Polyphenols, Tannic Acid

Diseases : Cancers

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

[+]

A cordyceps sinensis extract has a pro-apoptic effect on human lung adenocarcinoma A549 cells. Oct 01, 2011

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Pubmed Data : J Cancer Res Ther. 2011 Oct-Dec;7(4):421-6. PMID: 22269403

Article Published Date : Oct 01, 2011

Study Type : Human In Vitro

Additional Links

Diseases : Lung Cancer

Pharmacological Actions : Apoptotic, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.Mar 29, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biochem Biophys Res Commun. 2004 Mar 12 ;315(3):589-94. PMID: 14975741

Article Published Date : Mar 12, 2004

Study Type : Human In Vitro

Additional Links

Diseases : Glioma

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutrition. 2015 Apr ;31(4):578-81. Epub 2014 May 29. PMID: 25220876

Article Published Date : Mar 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Capsaicin

Diseases : Bladder Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2012 Jan ;5(1):196-201. Epub 2011 Sep 30. PMID: 21964700

Article Published Date : Dec 31, 2011

Study Type : Human In Vitro

Additional Links

Substances : Pumpkin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

[+]

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Breast Cancer. 2015 Sep ;18(3):225-34. Epub 2015 Sep 24. PMID: 26472972

Article Published Date : Aug 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Citral, Curcumin, Lemongrass

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Dose Response, Natural Substance Synergy, Selective Cytotoxicity

[+]

Curcumin inhibited proliferation and induced apoptosis in both KG-1 and U937 cells.Jun 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Hematol Oncol Stem Cell Res. 2016 Jul 1 ;10(3):120-9. PMID: 27489587

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Pubmed Data : Nat Prod Res. 2015 Nov 2:1-4. Epub 2015 Nov 2. PMID: 26525080

Article Published Date : Nov 01, 2015

Study Type : Human In Vitro

Additional Links

Substances : Goji

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Chemopreventive

Additional Keywords : Dose Response, Plant Extracts, Selective Cytotoxicity

[+]

Graviola extracts inhibited the proliferation of HL-60 cells in a concentration dependent manner and induced apoptosis.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 Mar 31 ;62(3):72-7. Epub 2016 Mar 31. PMID: 27064876

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Phytother Res. 2012 May 8. Epub 2012 May 8. PMID: 22566066

Article Published Date : May 08, 2012

Study Type : Human In Vitro

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Ginseng, Green Tea, Panaxadiol

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance Synergy

[+]

Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.Mar 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Nanomedicine. 2016 ;11:4991-5002. Epub 2016 Aug 3. PMID: 27757032

Article Published Date : Dec 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Myricetin

Diseases : Glioblastoma

Pharmacological Actions : Apoptotic, Cytotoxic, MicroRNA modulator

[+]

Promising cytotoxic activity profile of fermented wheat germ extract in human cancer cell lines.Apr 15, 2011

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Pubmed Data : J Exp Clin Cancer Res. 2011 Apr 16 ;30:42. Epub 2011 Apr 16. PMID: 21496306

Article Published Date : Apr 15, 2011

Study Type : Human In Vitro

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Substances : Fermented Foods and Beverages, Wheat Germ

Diseases : Cancers

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Oxaliplatin, Plant Extracts

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Pubmed Data : Cell Physiol Biochem. 2016 Jul 15 ;39(2):604-616. Epub 2016 Jul 15. PMID: 27415599

Article Published Date : Jul 14, 2016

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Pubmed Data : Int J Food Sci Nutr. 2019 Aug ;70(5):570-578. Epub 2019 Jan 9. PMID: 30624124

Article Published Date : Aug 01, 2019

Study Type : Human In Vitro

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Substances : Sulforaphane

Diseases : Gastric Cancer, Gastric Cancer: Prevention

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Anti-cancer

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Sulforaphene inhibits liver cancer cell proliferation by stimulating apoptosis and causing cytotoxicity.Jun 04, 2018

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Pubmed Data : Nutrients. 2018 Jun 4 ;10(6). Epub 2018 Jun 4. PMID: 29866995

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Pubmed Data : Cancer Cell Int. 2015 ;15:33. Epub 2015 Mar 29. PMID: 25859163

Article Published Date : Dec 31, 2014

Study Type : Human In Vitro

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Substances : Apigenin

Diseases : Bladder Cancer, Bladder Cancer: Prevention

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, P21 Activation, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Dose Response

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The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.Dec 31, 2014

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Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells.May 28, 2022

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

This meta-analysis implies moderation in capsaicin consumption in order to derive its protective benefits.Aug 31, 2014

Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.Oct 01, 2010

Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.Sep 30, 2015

Chinese motherwort has cytotoxicity against human breast cancer cells that is non-apoptic and estrogen receptor independent. Mar 18, 2009

Curcumin induces programmed cell death in human malignant gliobastoma cells - Article 2. Oct 16, 2006

Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).Aug 01, 2010

Danggui can prolong the survival rate of gastric cancer patients in Taiwan.Dec 31, 2017

EPA (eicosapentaenoic acid) induces programmed cell death in human pancreatic cancer cells. Oct 01, 2005

Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients.Jun 17, 2022

Grape seed procyanidin extract mediates antineoplastic effects against lung cancer.Nov 30, 2016

Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.Jan 01, 2000

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

HLA-DQ2/8 genes may not cause gluten-associated villous atrophy, rather, be activated as a consequence of the pathological process. Dec 31, 2004

Hyperbaric oxygen therapy may be an appropriate therapeutic regimen for the treatment of patients with osteosarcoma.Nov 01, 2009

Metabolised pycnogenol induces apoptosis in human fibrosarcoma cells.Mar 31, 2015

Mistletoe extract is known to induce apoptosis and immunactivation in chronic lymphocytic leukemia, and has been shown to have a non-propogating effect on leukemic cells.Nov 01, 2007

Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.Feb 16, 2015

Molecular iodine-treated tumors exhibit less invasive potential, and significant increases in apoptosis, estrogen receptor expression, and immune cell infiltration.Jul 16, 2019

N-acetylcysteine compares favorably to metformin on mammographic density in postmenopausal women.Dec 31, 2011

Puerarin: A potential therapeutic for colon adenocarcinoma patients suffering from SARS-CoV-2 infection.Dec 31, 2021

Soy isoflavones may benefit some patients with prostate cancer. Jan 01, 2003

Suppression of pro-inflammatory and pro-survival biomarkers in oral cancer patients consuming a black raspberry phytochemical-rich troche.Dec 22, 2015

The bioactivity of garlic is multifaceted and includes activation of genes related to immunity, apoptosis, and xenobiotic metabolism in humans and Mono Mac 6 cells.Sep 29, 2015

The effect of dietary intervention with high-oleocanthal and oleacein olive oil in Patients with early-stage chronic lymphocytic leukemia.Dec 31, 2020

The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.Dec 31, 2012

The Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium.Feb 01, 2011

The present RCT provides evidence that serum from patients taking the extract showed cytotoxicity against human colorectal cancer cell lines. Dec 31, 2016

These pilot data suggest that a flaxseed-supplemented, fat-restricted diet may affect prostate cancer biology and associated biomarkers.Jun 30, 2001

Those with celiac disease may experience neurological damage as a result of the intolerance. Jul 01, 2007

Tomato sauce supplementation reduces prostate cancer growth in men.Nov 01, 2002

Treatment with melittin induces apoptosis and autophagy of fibroblastlike synoviocytes in patients with rheumatoid arthritis.Dec 31, 2019

Verbena officinalis essential oil and its component citral has apoptoic-inducing activity against chronic lymphocytic leukemia.Oct 01, 2009

Vitamin E taken orally for 2 weeks before pancreatic surgery significantly induced apoptosis in the neoplastic cells of patients with pancreatic ductal neoplasia.Nov 30, 2015

1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.Oct 01, 2011

A cordyceps sinensis extract has a pro-apoptic effect on human lung adenocarcinoma A549 cells. Oct 01, 2011

A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.Mar 29, 2014

A Nigella sativa extract showed a 88.3% inhibition of proliferation of SiHa human cervical cancer cells and increased the expression of caspase-3, -8 and -9 several-foldJan 31, 2013

A water extract of Withania somnifera has potent cytotoxic effect on human malignant melanoma A375 cells.Dec 31, 2014

Alpha-bisobolol strongly induces apoptosis in glioma cells.Mar 12, 2004

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

An extract of Amla fruit inhibited human papillomavirus viral oncogenes responsible for development and progression of cervical cancer.Dec 31, 2012

An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.Dec 31, 2014

Anti-cancer activity of bromelain nanoparticles by oral administration.Nov 30, 2014

Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage associated with infertility.Oct 01, 2010

Anti-tumour effects of beta-sitosterol are mediated by AMPK/PTEN/HSP90 axis in AGS human gastric adenocarcinoma cells.Dec 31, 2017

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.Nov 30, 2013

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Arctigenin is able to inhibit cell proliferation and may induce apoptosis and cell cycle arrest at the G0/G1 phase in glioma cells.Jan 31, 2017

Baicalein induces caspase-dependent apoptosis in human lung carcinoma A549 cells.Feb 29, 2016

Berberine induced apoptosis and DNA damage in human osteosarcoma lines that were treated.Sep 30, 2014

Berberine suppressed the progression of human glioma cells.Dec 31, 2021

Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.Dec 31, 2014

Camel milk inhibited HepG2 and MCF7 cells survival and proliferation.Dec 31, 2011

Capsaicin induced apoptosis in human bladder cancer cells activates dendritic cells.Mar 31, 2015

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Chaga mushroom extract can inhibit the proliferation of tumor cells.Dec 31, 2013

Chrysin induces apoptosis of human uveal melanoma cells.Nov 30, 2016

Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.Aug 31, 2015

Combined application of Grifola frondosa and vitamin C induced cell apoptosis and autophagy in vitro.Sep 10, 2017

Cucurbitacin B in the combination with curcumin could serve as a novel, promising approach for human hepatoma.Oct 05, 2015

Cucurmosin has potential anticancer activity for human hepatoma.Dec 31, 2011

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

Curcumin inhibited proliferation and induced apoptosis in both KG-1 and U937 cells.Jun 30, 2016

Curcumin treatment causes a rapid increase in reactive oxygen species and a decrease in the mitochondrial membrane potential-events leading to apoptosis activation.Nov 30, 2014

Dandelion root induces selective apoptosis and autophagy in human pancreatic cancer cells in a dose and time dependent manner.Sep 30, 2012

Delta tocotrienol might represent an effective option for chemopreventive strategies for melanoma.Dec 31, 2015

Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.Sep 01, 2008

Electromagnetic field exposure induces caspase 3 activation, a protein involved in apoptosis as well as other cellular processes.Sep 01, 2008

Electromagnetic fields induce astrocytoma proliferation in vitro.Jan 12, 2009

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6461 Abstracts with Apoptotic Research