Bax/Bcl2 ratio: Increase

Views 378
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
31 Substances Researched for Bax/Bcl2 ratio: Increase
NameACCKFocus
Curcumin48Locked
Piperine15Locked
Anthocyanins12Locked
Black Currant12Locked
Burdock22Locked
Cordyceps Militaris22Locked
Ellagic Acid12Locked
Ginkgo biloba12Locked
Pomegranate12Locked
Pomegranate Peel22Locked
Quercetin22Locked
Shiitake Mushroom 12Locked
Astaxanthin11Locked
Cannabinoids: Synthetic11Locked
Cyanidin 3-glucoside11Locked
Epimedium11Locked
Flaxseed11Locked
Garlic11Locked
Genistein11Locked
Gingerol 11Locked
Holy Basil11Locked
Huaier (Trametes robiniophila murr)11Locked
Loquat Leaves11Locked
Melatonin11Locked
Molasses11Locked
Oridonin11Locked
Phellinus Linteus11Locked
Polyphenols11Locked
Puerarin11Locked
Tocotrienol: Delta11Locked
Whey11Locked

View the Evidence:
38 Abstracts with Bax/Bcl2 ratio: Increase Research

[+]

Piperine was found to exert selective cytotoxic effects against A549 cells in a dose-dependent manner.Mar 31, 2014

Pubmed Data : Tumour Biol. 2014 Apr ;35(4):3305-10. Epub 2013 Nov 24. PMID: 24272201
Article Published Date : Mar 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Piperine
Diseases : Lung Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Selective Cytotoxicity
[+]

A water-extracted polysaccharide from Lentinus edodes exerts direct antitumor effects by inducing apoptosis in colon cancer cells.Nov 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Nov 21. Epub 2016 Nov 21. PMID: 27888812
Article Published Date : Nov 20, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shiitake Mushroom
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Caspase-3 Activation, NF-kappaB Inhibitor
Additional Keywords : Polysaccharides
[+]

Anthocyanin-rich black currant extract affords chemoprevention against chemically-induced liver cancer in rats.Jan 07, 2011

Pubmed Data : J Nutr Biochem. 2011 Jan 7. Epub 2011 Jan 7. PMID: 21216582
Article Published Date : Jan 07, 2011
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Black Currant
Diseases : Chemically-Induced Liver Damage, Liver Cancer
Pharmacological Actions : Bax/Bcl2 ratio: Increase, Chemopreventive
[+]

Ginkgo biloba exocarp extracts induces apoptosis in Lewis lung cancer cells via mitochondrial-mediated intrinsic pathway.Jan 19, 2017

Pubmed Data : J Ethnopharmacol. 2017 Jan 20. Epub 2017 Jan 20. PMID: 28115284
Article Published Date : Jan 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Dose Response
[+]

Hair growth activity of Crataegus pinnatifida on C57BL/6 mouse model.Aug 31, 2013

Pubmed Data : Phytother Res. 2013 Sep ;27(9):1352-7. Epub 2012 Nov 12. PMID: 23148028
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Hawthorn
Diseases : Hair Loss
Pharmacological Actions : Anti-Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Lipophilic grape seed proanthocyanidin exerts anti-cervical cancer effects.Feb 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Feb 19 ;11(2). Epub 2022 Feb 19. PMID: 35204304
Article Published Date : Feb 18, 2022
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract, Proanthocyanidins
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest
[+]

Pomegranate fruit juice suppressed androgen dependent prostate carcinogenesis.Oct 03, 2014

Pubmed Data : Prostate. 2014 Oct 4. Epub 2014 Oct 4. PMID: 25284475
Article Published Date : Oct 03, 2014
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Pomegranate
Diseases : Cancer: Prostate, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Caspase-3 Activation, Chemopreventive
[+]

Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway.Jan 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2018 01 11 ;9(1):15. Epub 2018 Jan 11. PMID: 29323103
Article Published Date : Jan 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Osteosarcoma
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation, NF-kappaB Inhibitor
[+]

"Quercetin inhibits human breast cancer cell proliferation and induces apoptosis via Bcl-2 and Bax regulation."Jun 01, 2012

Pubmed Data : Mol Med Report. 2012 Jun ;5(6):1453-6. Epub 2012 Mar 22. PMID: 22447039
Article Published Date : Jun 01, 2012
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase
[+]

6-Gingerol with 5-flourouracil and paclitaxel resulted in 83.2% and 52% inhibition of cervical cancer cells. Feb 26, 2017

Pubmed Data : Food Chem Toxicol. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28249781
Article Published Date : Feb 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Paclitaxel
[+]

A homogeneous polysaccharide from Huaier inhibited the proliferation of human osteosarcoma cancer cells by promoting apoptosis.Jun 30, 2015

Pubmed Data : Tumour Biol. 2015 Jul ;36(7):5255-63. Epub 2015 Feb 11. PMID: 25666751
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Huaier (Trametes robiniophila murr)
Diseases : Osteosarcoma
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation
Additional Keywords : Dose Response
[+]

An ethyl acetate extract of burdock may be a promising neuroprotective agent for the prevention and treatment of neurodegenerative diseases.Jun 30, 2014

Pubmed Data : Environ Toxicol Pharmacol. 2014 Jul ;38(1):189-98. Epub 2014 Jun 7. PMID: 24956398
Article Published Date : Jun 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Oxidative Stress
Pharmacological Actions : Bax/Bcl2 ratio: Increase, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Astaxanthin demonstrates anti-cancer activity against liver cancer.Jan 01, 2011

Pubmed Data : Biol Pharm Bull. 2011;34(6):839-44. PMID: 21628881
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation
[+]

Burdock extracts may be regarded as potential antioxidant agents and possess potent neuroprotective activity against H2O2-induced injury.Mar 31, 2015

Pubmed Data : Cell Mol Neurobiol. 2015 Apr ;35(3):335-44. Epub 2014 Oct 29. PMID: 25352420
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Bax/Bcl2 ratio: Increase, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Cordycepin induces apoptosis in human bladder cancer T24 cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Trends. 2019 ;13(4):324-333. PMID: 31527329
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
[+]

Curcumin induces programmed cell death in hepatoma cells.Jan 01, 2011

Pubmed Data : Asian Pac J Cancer Prev. 2011 ;12(8):1925-9. PMID: 22292626
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Hepatoma
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase
[+]

Curcumin may be considered a novel therapeutic strategy to inhibit gastric cancer cell growth.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):5156-5162. Epub 2016 Nov 4. PMID: 28105222
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Bax/Bcl2 ratio: Increase, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Antiproliferative, CURCUMIN, gastric cancer
[+]

Curcumin nanoencapsulation with whey protein had enhanced colon cancer chemoprevention effects.Jul 08, 2016

Pubmed Data : Eur J Pharmacol. 2016 Jul 9. Epub 2016 Jul 9. PMID: 27404761
Article Published Date : Jul 08, 2016
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Whey
Diseases : Colon Cancer
Pharmacological Actions : Bax/Bcl2 ratio: Increase, Chemopreventive, Tumor Suppressor Protein p53 Upregulation
[+]

Cyanidin-3-O-glucoside chloride exhibits cytotoxicity on Caco-2 cells in vitro and induces apoptosis in Caco-2 cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(7). Epub 2016 Jun 23. PMID: 27347927
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cyanidin 3-glucoside, Molasses
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest, Cyclin D1 Down-Regulation, Cytotoxic
[+]

Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer.Jun 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2021 Jun 10 ;21(1):304. Epub 2021 Jun 10. PMID: 34112163
Article Published Date : Jun 09, 2021
Study Type : In Vitro Study
Additional Links
Substances : Echinacea
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Transforming growth factor beta (TGF-β) upregulation
[+]

Fresh garlic juice induces apoptosis in the KB cells through increasing caspase-3 activity and Bax:Bcl2 ratio.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent Res Dent Clin Dent Prospects. 2015 ;9(4):267-73. Epub 2015 Dec 30. PMID: 26889365
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Garlic
Diseases : Oral Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase
[+]

Hispolon from Phellinus linteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells.Dec 31, 2012

Pubmed Data : Am J Chin Med. 2013 ;41(6):1439-57. PMID: 24228611
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Phellinus Linteus, Polyphenols
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Cyclin D1 Down-Regulation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Icariin and its derivatives are shown to be compounds with tremendous potential for the treatment of cancers.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:191. Epub 2016 Jun 29. PMID: 27445824
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Epimedium
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest, Immunomodulatory
[+]

Isothiocyanate From Moringa oleifera seeds inhibits the growth and migration of renal cancer cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:790618. Epub 2022 Jan 4. PMID: 35059399
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanate, Moringa oleifera
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Bax/Bcl2 ratio: Increase
[+]

Loquat leaves induce programmed cell death in human leukemia cell lines. Jan 01, 2011

Pubmed Data : Chem Pharm Bull (Tokyo). 2011;59(3):378-81. PMID: 21372421
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Loquat Leaves
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Caspase-2 Activation
[+]

Melatonin might be a novel adjuvant therapy and may confer advantages for breast cancer treatment.Jul 14, 2016

Pubmed Data : Biomed Pharmacother. 2016 Jul 15 ;83:456-465. Epub 2016 Jul 15. PMID: 27427852
Article Published Date : Jul 14, 2016
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest, Chemotherapeutic, P21 Activation
Problem Substances : Arsenic Trioxide
[+]

Ocimum sanctum essential oil has the ability to inhibit the proliferation of MCF-7 cells by inducing apoptosis.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2016 May ;12(Suppl 3):S327-31. PMID: 27563220
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Essential Oils
[+]

Orbitides isolated from flaxseed induce apoptosis against SGC-7901 adenocarcinoma cells.Apr 11, 2020

Pubmed Data : Int J Food Sci Nutr. 2020 Apr 12:1-11. Epub 2020 Apr 12. PMID: 32281434
Article Published Date : Apr 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flaxseed
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase
[+]

Physiological concentrations of genistein and 17β-estradiol inhibit breast cancer cell growth.Mar 31, 2012

Pubmed Data : Anticancer Res. 2012 Apr ;32(4):1181-91. PMID: 22493348
Article Published Date : Mar 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Paradox: Estrogen Kills Breast Cancer?
[+]

Pomegranate peel extract could be a promising drug candidate to treat prostate cancer.Jul 13, 2017

Pubmed Data : Biomed Pharmacother. 2017 Jul 14 ;93:976-984. Epub 2017 Jul 14. PMID: 28724216
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Bax/Bcl2 ratio: Increase
Additional Keywords : Plant Extracts
[+]

Pomegranate peel polyphenols could inhibit the growth of HepG2 cells by blocking the cell cycle and inducing the mitochondrial apoptotic pathway.Apr 23, 2016

Pubmed Data : Food Chem Toxicol. 2016 Apr 24. Epub 2016 Apr 24. PMID: 27120393
Article Published Date : Apr 23, 2016
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Puerarin inhibited cadmium induced apoptosis in rPT cells by ameliorating the mitochondrial dysfunction.Dec 24, 2016

Pubmed Data : Chem Biol Interact. 2016 Dec 25 ;260:219-231. Epub 2016 Oct 4. PMID: 27717697
Article Published Date : Dec 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cadmium Poisoning
Pharmacological Actions : Anti-Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Anti-Apoptotic, Bax/Bcl2, Cadmium, Cadmium Poisoning, Puerarin
Problem Substances : Cadmium
[+]

Quercetin seems to be a promising approach for primary liver tumors through GLUT-1 competitive inhibition.Mar 03, 2016

Pubmed Data : Nutr Cancer. 2016 Mar 4:1-17. Epub 2016 Mar 4. PMID: 26943884
Article Published Date : Mar 03, 2016
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

The inhibitory effect of cordycepin on the proliferation of MCF-7 breast cancer cells, and its mechanism.Aug 22, 2019

Pubmed Data : Biomolecules. 2019 Aug 23 ;9(9). Epub 2019 Aug 23. PMID: 31450828
Article Published Date : Aug 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
[+]

This study demonstrated for the first time that δ-T3 is a potent agent against human bladder cancer cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(4):e0122712. Epub 2015 Apr 7. PMID: 25849286
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest, Chemosensitizer, STAT3 Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Thymoquinone and costunolide induce apoptosis of both proliferative and doxorubicin-induced-senescent colon and breast cancer cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2021 Jan-Dec;20:15347354211035450. PMID: 34490824
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Breast Cancer, Colon Cancer
Pharmacological Actions : Antiproliferative , Bax/Bcl2 ratio: Increase
[+]

WIN induces a clear apoptotic effect which was accompanied by up-regulation of the death signaling factors and down regulation of the survival factors.Mar 31, 2009

Pubmed Data : Biochimie. 2009 Apr ;91(4):457-65. Epub 2008 Nov 27. PMID: 19059457
Article Published Date : Mar 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation, Survivin Down-Regulation
[+]

Zerumbone sensitizes the anti-cancer efficacy of cisplatin in hepatocellular carcinoma cells.Mar 23, 2022

Pubmed Data : Anticancer Agents Med Chem. 2022 Mar 24. Epub 2022 Mar 24. PMID: 35331096
Article Published Date : Mar 23, 2022
Study Type : In Vitro Study
Additional Links
Substances : Zerumbone
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest
Additional Keywords : Chemotherapeutic Synergy: Cisplatin

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.
  • Printer-friendly version

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.