Cannabinoid Receptor Antagonist/Inverse Agonist

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7 Substances Researched for Cannabinoid Receptor Antagonist/Inverse Agonist
NameACCKFocus
Cannabinoids: Synthetic46Locked
Cannabinoids 24Locked
Delta-tetrahydrocannabinol (THC)12Locked
Cannabidiol11Locked
Curcumin11Locked
Endocannabinoids11Locked
Resveratrol11Locked

View the Evidence:
7 Abstracts with Cannabinoid Receptor Antagonist/Inverse Agonist Research

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Cannabinoid receptor agonists HU210 and Delta(9)-tetrahydrocannabinol lowers the viability of translocation-positive rhabdomyosarcoma cells through the induction of apoptosis.Jun 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer Ther. 2009 Jul ;8(7):1838-45. Epub 2009 Jun 9. PMID: 19509271
Article Published Date : Jun 30, 2009
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Cannabinoids: Synthetic, Delta-tetrahydrocannabinol (THC)
Diseases : Rhabdomyosarcoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cannabinoid Receptor Antagonist/Inverse Agonist, Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin
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The discovery of IL-12-induced CB2 overexpression in thyroid cancer cells may offer a new target for anaplastic thyroid cancer treatmentJan 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Gene Ther. 2008 Feb ;15(2):101-7. Epub 2007 Dec 21. PMID: 18197164
Article Published Date : Jan 31, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Cannabinoids: Synthetic
Diseases : Thyroid Cancer
Pharmacological Actions : Apoptotic, Cannabinoid Receptor Antagonist/Inverse Agonist, Chemosensitizer
Additional Keywords : Cannabinoid Receptors, Chemothapeutic Synergy: Paclitaxel
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Cannabinoid receptor agonists, including WIN, may be considered as novel therapeutics for the treatment of hepatocellular carcinoma.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Dec ;12(6):7963-70. Epub 2015 Oct 23. PMID: 26500101
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Cannabinoid Receptor Antagonist/Inverse Agonist, Matrix metalloproteinase-9 (MMP-9) inhibitor
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The ability of cannabidiol to behave as a CB2 receptor inverse agonist may contribute to its documented anti-inflammatory properties.Feb 28, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2007 Mar ;150(5):613-23. Epub 2007 Jan 22. PMID: 17245363
Article Published Date : Feb 28, 2007
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cannabinoid Receptor Antagonist/Inverse Agonist
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The cannabinoid system could be a potential target for pharmacological treatment of Kaposi's sarcoma.Aug 14, 2009

Pubmed Data : Eur J Pharmacol. 2009 Aug 15 ;616(1-3):16-21. Epub 2009 Jun 17. PMID: 19539619
Article Published Date : Aug 14, 2009
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Kaposi Disease
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cannabinoid Receptor Antagonist/Inverse Agonist
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The dietary polyphenols trans-resveratrol and curcumin interact with cannabinoid receptors indicating their potential role in treating obesity and/or drug dependence. Jun 01, 1996

Pubmed Data : Biosci Biotechnol Biochem. 1996 Jun;60(6):1000-5. PMID: 19359525
Article Published Date : Jun 01, 1996
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Marijuana Addiction/Withdrawal, Obesity
Pharmacological Actions : Appetite Suppresant, Cannabinoid Receptor Antagonist/Inverse Agonist
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This review discusses how the endocannabinoid system can help treat diseases of the skin.Jul 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trends Pharmacol Sci. 2009 Aug ;30(8):411-20. Epub 2009 Jul 14. PMID: 19608284
Article Published Date : Jul 31, 2009
Study Type : Review
Additional Links
Substances : Endocannabinoids
Diseases : Acne, Allergies, Dermatitis, Dry Skin , Inflammation, Psoriasis, Seborrheic Keratosis, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Cannabinoid Receptor Antagonist/Inverse Agonist
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System

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