Cardiovascular Agents

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33 Substances Researched for Cardiovascular Agents
NameACCKFocus
Coenzyme Q10230Locked
Arginine220Locked
Vitamin D120Locked
Chocolate110Locked
Cocoa110Locked
Fiber110Locked
Flavonoids110Locked
Fruit: All110Locked
Ginkgo biloba110Locked
Monounsaturated fatty acids110Locked
Oats110Locked
Polyunsaturated Fatty Acids (PUFAs)110Locked
Pomegranate110Locked
Resveratrol110Locked
Saturated fatty acids110Locked
Curcumin47Locked
Nobiletin 15Locked
Omega-3 Fatty Acids23Locked
Black Tea12Locked
Black Tea Theaflavins12Locked
Flaxseed12Locked
Hibiscus sabdariffa 12Locked
Olive leaf extract12Locked
Quince12Locked
Saffron12Locked
Anthocyanins11Locked
Apigenin11Locked
Barley11Locked
Beet11Locked
Blueberry11Locked
DHA (Docosahexaenoic Acid)11Locked
EPA (Eicosapentaenoic Acid)11Locked
Milk Thistle11Locked

View the Evidence:
35 Abstracts with Cardiovascular Agents Research

[+]

Higher consumption of fruit and vegetables is associated with a lower risk of all cause mortality, particularly cardiovascular mortality.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 2014 ;349:g4490. Epub 2014 Jul 29. PMID: 25073782
Article Published Date : Dec 31, 2013
Study Type : Meta Analysis
Additional Links
Diseases : All-Cause Mortality, Cancers: All, Cardiovascular Diseases
Pharmacological Actions : Cardiovascular Agents
Additional Keywords : Dose Response, Risk Reduction
[+]

Patients with heart failure who used coenzyme Q10 had lower mortality and a higher exercise capacity improvement than the placebo.Jul 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cardiovasc Disord. 2017 Jul 24 ;17(1):196. Epub 2017 Jul 24. PMID: 28738783
Article Published Date : Jul 23, 2017
Study Type : Meta Analysis
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardiovascular Agents
[+]

Vitamin D supplementation might protect against cardiac failure in older people but does not appear to protect against MI or stroke.Aug 31, 2014

Pubmed Data : Am J Clin Nutr. 2014 Sep ;100(3):746-55. Epub 2014 Jul 23. PMID: 25057156
Article Published Date : Aug 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Heart Failure, Vitamin D Deficiency
Pharmacological Actions : Cardiovascular Agents
Additional Keywords : Risk Reduction, Significant Treatment Outcome
[+]

Consumption of high flavanol dark chocolate confers modest improvements in cardiovascular function.Jul 31, 2015

Pubmed Data : Vascul Pharmacol. 2015 Aug ;71:70-8. Epub 2015 Apr 11. PMID: 25869509
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Substances : Chocolate, Cocoa, Flavonoids
Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases
Pharmacological Actions : Cardiovascular Agents
[+]

Coq10 used as an adjunctive therapy in heart failure improves clinical signs and symptoms in the majority of patients tested. Jan 01, 1994

Pubmed Data : Mol Aspects Med. 1994;15 Suppl:s287-94. PMID: 7752841
Article Published Date : Jan 01, 1994
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardiovascular Agents
[+]

Daily resveratrol consumption may help to prevent and control cardiovascular disease in overweight or obese individuals.Jul 25, 2016

Pubmed Data : Obes Rev. 2016 Jul 26. Epub 2016 Jul 26. PMID: 27456934
Article Published Date : Jul 25, 2016
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Cardiovascular Diseases, Obesity, Overweight
Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Cardiovascular Agents, Hypoglycemic Agents
Additional Keywords : Risk Reduction
[+]

Fiber and fruit intakes are associated with a reduction in total mortality.Nov 30, 2014

Pubmed Data : Am J Clin Nutr. 2014 Dec ;100(6):1498-507. Epub 2014 Sep 10. PMID: 25411285
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Fiber, Fruit: All
Diseases : All-Cause Mortality, Cardiovascular Diseases
Pharmacological Actions : Cardioprotective, Cardiovascular Agents
Additional Keywords : Risk Factors
[+]

Gingko biloba compares favorably to the drug donepezil in the treatment of dementia.Sep 01, 2009

Pubmed Data : Fortschr Neurol Psychiatr. 2009 Sep;77(9):494-506. Epub 2009 Jul 20. PMID: 19621278
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Dementia
Pharmacological Actions : Cardiovascular Agents
Additional Keywords : Donepezil Alternatives, Natural Substances Versus Drugs, Plant Extracts
[+]

Green oat extract supplementation can improve vasodilator function in systemic and cerebral arteries.Dec 31, 2012

Pubmed Data : J Hypertens. 2013 Jan ;31(1):192-200. PMID: 23221935
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Oats
Pharmacological Actions : Cardioprotective, Cardiovascular Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

L-arginine protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease.May 01, 2009

Pubmed Data : Atherosclerosis. 2009 May;204(1):73-8. Epub 2008 Sep 4. PMID: 18849028
Article Published Date : May 01, 2009
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Coronary Artery Disease, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2, Endothelial Dysfunction
Pharmacological Actions : Cardiovascular Agents, Vasodilator Agents
[+]

L-Arginine, the substrate for NO synthesis, may be an alternative treatment for premature atherosclerosis.Apr 04, 2007

Pubmed Data : Int J Cardiol. 2007 Apr 4;116(3):300-8. Epub 2006 Jul 24. PMID: 16860889
Article Published Date : Apr 04, 2007
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Atherosclerosis, Endothelial Dysfunction
Pharmacological Actions : Antihypertensive Agents, Cardiovascular Agents, Nitric Oxide Enhancer
[+]

MUFAs or n-6 PUFAs had beneficial effects on serum lipid biomarkers, blood pressure, and E-selectin offering a potential public health strategy for CVD risk reduction.May 26, 2015

Pubmed Data : Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID: 26016869
Article Published Date : May 26, 2015
Study Type : Human Study
Additional Links
Substances : Monounsaturated fatty acids, Polyunsaturated Fatty Acids (PUFAs), Saturated fatty acids
Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases
Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Cardiovascular Agents, Hypolipidemic
Additional Keywords : Risk Reduction
[+]

Pomegranate juice intake had a significant beneficial effect, lowering systolic blood pressure and improving the lipid profiles of hemodialysis patients.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2014 ;13:18. Epub 2014 Mar 4. PMID: 24593225
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Atherosclerosis, Cardiovascular Diseases, Hypertension, Kidney Failure, Oxidative Stress, Triglycerides: Elevated
Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Cardiovascular Agents
Additional Keywords : Phytotherapy
[+]

These findings indicate that resveratrol can significantly reduce red blood cell aggregation.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Ther. 2020 ;2020:7262474. Epub 2020 Jun 30. PMID: 32695229
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective, Cardiovascular Agents
[+]

Walking in the forest environment may promote cardiovascular relaxation.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:834360. Epub 2014 Feb 10. PMID: 24660018
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Disease: Prevention
Therapeutic Actions : Shinrin-yoku (taking in the atmosphere of the forest)
Pharmacological Actions : Cardiovascular Agents
[+]

These data suggest that nobiletin might be a potential antithrombotic agent of dietary origin.Mar 14, 2017

Pubmed Data : Biochem Pharmacol. 2017 Mar 15 ;128:26-33. Epub 2016 Dec 23. PMID: 28017776
Article Published Date : Mar 14, 2017
Study Type : Human In Vitro
Additional Links
Substances : Nobiletin
Diseases : Cholesterol: Oxidation, Oxidative Stress
Pharmacological Actions : Antithrombotic, Cardiovascular Agents, NF-kappaB Inhibitor
[+]

Andrographolide mitigates cardiac apoptosis to provide cardio-protection in high-fat-diet-induced obesity.May 31, 2020

Pubmed Data : Environ Toxicol. 2020 Jun ;35(6):707-713. Epub 2020 Feb 5. PMID: 32023008
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Cardioprotective, Cardiovascular Agents
[+]

Application of curcumin can inhibit expression of MMP-9, CD40L, TNF-α and CRP to improve the permeability of coronary artery.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(6):7247-53. Epub 2015 Jun 1. PMID: 26261622
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Atherosclerosis, C-Reactive Protein, Coronary Artery Disease, High Fat Diet
Pharmacological Actions : Cardiovascular Agents, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Black tea extract had protective benefits against endothelial dysfunction in hypertensive rats through alleviation of ER stress.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:10340. Epub 2015 May 15. PMID: 25976123
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Black Tea, Black Tea Theaflavins
Diseases : Endothelial Dysfunction, Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Cardiovascular Agents
[+]

Curcumin improves left ventricular function in pressure overloaded rabbits. Feb 01, 2004

Pubmed Data : Biol Pharm Bull. 2004 Feb;27(2):198-202. PMID: 14758033
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Left Ventricular Dysfunction, Left Ventricular Hypertrophy
Pharmacological Actions : Cardiovascular Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin prevents restenosis in a rabbit artery stent model. Nov 15, 2009

Pubmed Data : Catheter Cardiovasc Interv. 2009 Nov 15;74(6):881-8. PMID: 19496118
Article Published Date : Nov 15, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Coronary Artery Disease, Coronary Stenting , High Cholesterol
Pharmacological Actions : Antiproliferative , Cardioprotective, Cardiovascular Agents
[+]

OEE and HSE exerted negative inotropic and vasorelaxant effects without any chronotropic property with higher cytoprotective effects and antioxidant activities.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:318125. Epub 2015 Jun 9. PMID: 26180582
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Hibiscus sabdariffa , Olive leaf extract
Diseases : Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Cardiovascular Agents, Cytoprotective, Vasodilator Agents
Additional Keywords : Dose Response, Natural Substance Synergy, Plant Extracts
[+]

Omega-3 polyunsaturated fatty acids has a preventive effect against atrial fibrillation in a canine model of pericarditis.Apr 01, 2010

Pubmed Data : Heart Rhythm. 2010 Apr;7(4):520-8. Epub 2009 Dec 28. PMID: 20156610
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Atrial Fibrillation, Pericarditis
Pharmacological Actions : Cardiovascular Agents, Epidermal growth factor receptor (EGFR) inhibitor, JAM3 gene down-regulation , Myosin heavy chain alpha (MHCalpha) reducer, Protein Kinase Inhibitors
[+]

Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.Mar 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Res. 2012 Apr 1 ;94(1):144-53. Epub 2012 Jan 27. PMID: 22287575
Article Published Date : Mar 31, 2012
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Coronary Bypass Surgery, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardiovascular Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Prolonged flaxseed flour intake decreased the thickness of the aorta and modulates some modifiable risk factors related to cardiovascular disease in rats.Dec 31, 2013

Pubmed Data : Nutr Hosp. 2014 ;29(2):376-81. Epub 2014 Feb 1. PMID: 24528356
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Aortic Plaques, Cardiovascular Diseases
Pharmacological Actions : Cardioprotective, Cardiovascular Agents
[+]

Saffron acts as a calcium channel blocker on guinea-pig isolated heart. Mar 01, 2008

Pubmed Data : Phytother Res. 2008 Mar;22(3):330-4. PMID: 18058985
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Calcium Channel Blockers, Cardiovascular Agents
[+]

This confirns the experimental effects of quince on hemostasis and thrombosis.May 27, 2014

Pubmed Data : J Ethnopharmacol. 2014 May 28 ;154(1):163-9. Epub 2014 Apr 4. PMID: 24704668
Article Published Date : May 27, 2014
Study Type : Animal Study
Additional Links
Substances : Quince
Diseases : Thrombosis
Pharmacological Actions : Cardiovascular Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Apigenin protects endothelium-dependent relaxation of rat aorta against oxidative stress.Aug 15, 2009

Pubmed Data : Eur J Pharmacol. 2009 Aug 15;616(1-3):200-5. Epub 2009 Jun 21. PMID: 19549516
Article Published Date : Aug 15, 2009
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Endothelial Dysfunction
Pharmacological Actions : Cardiovascular Agents
[+]

Beetroot is a powerful dietary source of health promoting agents with potential as therapeutic treatment for several pathological disorders.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 Apr ;7(4):2801-22. Epub 2015 Apr 14. PMID: 25875121
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Beet
Diseases : Cognitive Decline/Dysfunction, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardiovascular Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Biological activities of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside in antiaging and antiaging-related disease treatments.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:4973239. Epub 2016 Jun 20. PMID: 27413420
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Aging, Alzheimer's Disease, Atherosclerosis, Brain Inflammation , Cerebral Ischemia, Fibrosis, Memory Disorders, Parkinson's Disease
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective, Cardiovascular Agents, Hypoglycemic Agents, Neuroprotective Agents
Additional Keywords : Phytotherapy
[+]

Curcumin has a protective role in cardiovascular diseases.Apr 03, 2009

Pubmed Data : Int J Cardiol. 2009 Apr 3;133(2):145-51. Epub 2009 Feb 23. PMID: 19233493
Article Published Date : Apr 03, 2009
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardiovascular Agents
[+]

Multiple pathways are responsible for anti-inflammatory and cardiovascular activities of Hordeum vulgare L.Nov 25, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2014 Nov 26 ;12:316. Epub 2014 Nov 26. PMID: 25428431
Article Published Date : Nov 25, 2014
Study Type : In Vitro Study
Additional Links
Substances : Barley
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardiovascular Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

This review article aims to present different aspects of Silybum marianum, especially the data in recently published articles about its effects on different diseases.Sep 30, 2015

Pubmed Data : J Evid Based Complementary Altern Med. 2015 Oct ;20(4):292-301. Epub 2015 Feb 16. PMID: 25686616
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Substances : Milk Thistle
Diseases : Alzheimer's Disease, Cancers: All, Insulin Resistance, Liver Cirrhosis, Liver Disease
Pharmacological Actions : Anti-atherogenic, Antioxidants, Cardiovascular Agents, Hepatoprotective, Hypolipidemic, Regenerative
[+]

This review highlights the recent developments in the understanding of the vascular effects of blueberries.Aug 24, 2016

Pubmed Data : Mol Nutr Food Res. 2016 Aug 25. Epub 2016 Aug 25. PMID: 27558887
Article Published Date : Aug 24, 2016
Study Type : Review
Additional Links
Substances : Anthocyanins, Blueberry
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardiovascular Agents
[+]

This review indicates that omega-3s and their oxygenated metabolites may play a role in preventing atherothrombosis.Apr 01, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochim Biophys Acta. 2015 Apr ;1851(4):485-95. Epub 2014 Sep 28. PMID: 25263947
Article Published Date : Apr 01, 2015
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Omega-3 Fatty Acids
Diseases : Atherosclerosis, Thrombosis
Pharmacological Actions : Cardioprotective, Cardiovascular Agents

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