Caspase-9 Activation

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53 Substances Researched for Caspase-9 Activation
NameACCKFocus
Bloodroot15Locked
Chrysin15Locked
Nigella sativa (aka Black Seed)15Locked
Piperine15Locked
Resveratrol33Locked
Ursolic Acid23Locked
Apple12Locked
Beet12Locked
Berberine12Locked
Betaine 12Locked
Bisdemethoxycurcumin22Locked
Curcuma Purpurascens 12Locked
Lichens22Locked
Mistletoe12Locked
Mushrooms: All 22Locked
Shemamruthaa12Locked
Tocotrienol: Delta12Locked
Vitamin E12Locked
Anthocyanins11Locked
Avocado11Locked
Blueberry11Locked
Cannabidiol11Locked
Carnosic Acid11Locked
Catechin 11Locked
Chickpea11Locked
Cucurbitacin E 11Locked
Curcumin11Locked
DHA (Docosahexaenoic Acid)11Locked
Demethoxycurcumin11Locked
EPA (Eicosapentaenoic Acid)11Locked
Gold (nanoparticles)11Locked
Hawthorn11Locked
Holy Basil11Locked
Isoflavones11Locked
Lion's Mane (Hericium Erinaceus)11Locked
Lithospermum erythrorhizon11Locked
Lotus 11Locked
Mango Seed11Locked
Medicinal Mushrooms11Locked
Melatonin11Locked
Moringa oleifera11Locked
Oridonin11Locked
Oyster Mushroom11Locked
Rosemary11Locked
Rutin11Locked
Shikonin11Locked
Tea11Locked
Tetrahydrocurcumin11Locked
Tomato11Locked
Tualang Honey11Locked
White Mulberry 11Locked
White Tea11Locked
Xanthohumol11Locked

View the Evidence:
47 Abstracts with Caspase-9 Activation Research

[+]

A Nigella sativa extract showed a 88.3% inhibition of proliferation of SiHa human cervical cancer cells and increased the expression of caspase-3, -8 and -9 several-foldJan 31, 2013

Pubmed Data : Nat Prod Commun. 2013 Feb ;8(2):213-6. PMID: 23513732
Article Published Date : Jan 31, 2013
Study Type : Human In Vitro
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Chrysin induces apoptosis of human uveal melanoma cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):4813-4820. Epub 2016 Oct 13. PMID: 28105189
Article Published Date : Nov 30, 2016
Study Type : Human In Vitro
Additional Links
Substances : Chrysin
Diseases : Melanoma: Uveal
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Piperine was found to exert selective cytotoxic effects against A549 cells in a dose-dependent manner.Mar 31, 2014

Pubmed Data : Tumour Biol. 2014 Apr ;35(4):3305-10. Epub 2013 Nov 24. PMID: 24272201
Article Published Date : Mar 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Piperine
Diseases : Lung Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 ratio: Increase, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Selective Cytotoxicity
[+]

Sanguinarine induces apoptosis of human oral squamous cell carcinoma KB cells.Jul 31, 2016

Pubmed Data : Drug Dev Res. 2016 Aug ;77(5):227-40. Epub 2016 Jul 1. PMID: 27363951
Article Published Date : Jul 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Bloodroot
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

An extract of Curcuma purpurascens suppressed the proliferation of HT-29 colon cancer cells and triggered the induction of apoptosis through mitochondrial-dependent pathway.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:15. Epub 2015 Feb 5. PMID: 25652758
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcuma Purpurascens
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation
Additional Keywords : Dose Response
[+]

Berberine activates apoptosis to suppress triple-negative breast cancer cells.Aug 17, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug 18 ;95:18-24. Epub 2017 Aug 18. PMID: 28826092
Article Published Date : Aug 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berberine
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Betanin significantly inhibits lung tumorigenesis in A/J mice and induces apoptosis in lung cancer cells. Aug 31, 2013

Pubmed Data : Mol Carcinog. 2013 Sep ;52(9):686-91. Epub 2012 Mar 27. PMID: 22456940
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Beet, Betaine
Diseases : Benzo[a]pyrene-induced Toxicity , Lung Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anticarcinogenic Agents, Apoptotic, Caspase-3 Activation, Caspase-7 Activation , Caspase-9 Activation, Chemopreventive
Additional Keywords : Beet, Benzo(a)pyrene, Betaine, lung cancer, Vinyl Carbamate
Problem Substances : Benzo(a)pyrene, Vinyl Carbamate
[+]

Oral administration of apple procyanidins inhibits the proliferation of tumor cells by inducing apoptosis through the intrinsic mitochondrial pathway.Feb 29, 2008

Pubmed Data : Carcinogenesis. 2008 Mar ;29(3):585-93. Epub 2007 Sep 7. PMID: 17827407
Article Published Date : Feb 29, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple
Diseases : Melanoma
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation
Additional Keywords : Proanthocyanidins
[+]

The herbal preparation Shemamruthaa had antiproliferative and apoptotic effects on chemically induced breast cancer.Sep 30, 2015

Pubmed Data : J Evid Based Complementary Altern Med. 2015 Oct ;20(4):259-68. Epub 2015 Apr 17. PMID: 25888591
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Shemamruthaa
Diseases : Breast Cancer, Breast Cancer: Chemically-Induced
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

These results suggest that the combination viscumTT may have a potential therapeutic value for the treatment AML.Dec 31, 2014

Pubmed Data : PLoS One. 2015;10(8):e0133892. Epub 2015 Aug 5. PMID: 26244918
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Mistletoe
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Caspase-8 activation, Caspase-9 Activation
Additional Keywords : Dose Response, Plant Extracts
[+]

Tocotrienols are potent antitumor agents capable of inducing apoptosis and inhibiting angiogenesis under both hypoxic and normoxic conditions.Jul 31, 2015

Pubmed Data : J Nutr Biochem. 2015 Aug ;26(8):832-40. Epub 2015 Apr 14. PMID: 25979648
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Tocotrienol: Delta, Vitamin E
Diseases : Colorectal Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest, P21 Activation
Additional Keywords : Dose Response
[+]

Ursolic acid exhibits significant anti-tumor effects by suppressing cell proliferation, promoting apoptosis in gallbladder cancer cells. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2014 ;14(1):96. Epub 2014 Oct 29. PMID: 25383044
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Abrogation of HDGF by EGCG enhances cisplatin-induced apoptosis and sensitizes A549 cells to chemotherapy.Jul 13, 2015

Pubmed Data : Proteomics Clin Appl. 2015 Jul 14. Epub 2015 Jul 14. PMID: 26175166
Article Published Date : Jul 13, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Avocado defensin could induce intrinsic apoptosis in breast cancer cells.Jul 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug ;82:620-7. Epub 2016 Jun 13. PMID: 27470405
Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Avocado
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Caspase-7 Activation , Caspase-9 Activation
Additional Keywords : Apoptotic, Avocado, Breast Cancer, Caspase-7 Activation, Caspase-9 Activation
[+]

Bisdemethoxycurcumin induced cell apoptosis through multiple signal pathways such as extrinsic, intrinsic and ES tress pathway.Sep 14, 2015

Pubmed Data : Environ Toxicol. 2015 Sep 15. Epub 2015 Sep 15. PMID: 26370218
Article Published Date : Sep 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Bisdemethoxycurcumin
Diseases : Lung Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, Cell cycle arrest
[+]

Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion.Nov 30, 2022

Pubmed Data : Oncol Rep. 2022 Dec ;48(6). Epub 2022 Oct 12. PMID: 36222295
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Bisdemethoxycurcumin
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Caspase-9 Activation, Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor
[+]

Blueberry anthocyanins inhibited proliferation and induced apoptosis in oral cancer cells in a dose dependent manner. Jun 19, 2014

Pubmed Data : Yi Chuan. 2014 Jun 20 ;36(6):566-73. PMID: 24929515
Article Published Date : Jun 19, 2014
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Blueberry
Diseases : Oral Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-9 Activation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Epigenetic Modification, Methylation Downregulation
[+]

Carnosic acid induced apoptosis in HCT116 cells via generation of ROS, induction of p53, activation of caspases, and inhibition of STAT3 signaling pathway.Jul 07, 2015

Pubmed Data : Mol Carcinog. 2015 Jul 8. Epub 2015 Jul 8. PMID: 26152521
Article Published Date : Jul 07, 2015
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Rosemary
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-9 Activation, STAT3 Inhibitor, Tumor Suppressor Protein p53 Upregulation
[+]

Curcumin could induce apoptosis in pancreatic cancer cells.Sep 30, 2015

Pubmed Data : Mol Med Rep. 2015 Oct ;12(4):5415-22. Epub 2015 Jul 8. PMID: 26166196
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 Ratio: Decrease, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest
[+]

Demethoxycurcumin may induce apoptosis of skin cancer cells through a caspase dependent pathway.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Jul ;16(1):539-546. Epub 2017 May 31. PMID: 28586041
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Demethoxycurcumin
Diseases : Skin Cancer: Squamous Cell
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

DHA and EPA are found to exhibit growth-inhibitory effect on the human neuroblastoma LA-N-1 cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(8):6956-73. Epub 2015 Aug 18. PMID: 26295255
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid)
Diseases : Neuroblastoma
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest
[+]

Hyperoside and rutin from lotus roots may be the promising candidates for treatment of colon cancer.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Apr ;11(4):2463-2470. Epub 2016 Feb 18. PMID: 27073499
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus , Rutin
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation
[+]

In the current study we demonstrated that cannabidiol can induce apoptosis in murine as well as human leukemia cells.Aug 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Pharmacol. 2006 Sep ;70(3):897-908. Epub 2006 Jun 5. PMID: 16754784
Article Published Date : Aug 31, 2006
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, NADPH Oxidase Inhibitors
Additional Keywords : Cannabinoid Receptors
[+]

Isoflavones extracted from chickpea sprouts induce mitochondria-dependent apoptosis in human breast cancer cells.Jan 31, 2015

Pubmed Data : Phytother Res. 2015 Feb ;29(2):210-9. Epub 2014 Oct 7. PMID: 25287332
Article Published Date : Jan 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chickpea, Isoflavones
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Caspase-7 Activation , Caspase-9 Activation, Chemopreventive, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Lethariella zahlbruckneri extract inhibited HT-29 cell proliferation by inducing apoptosis.Aug 31, 2009

Pubmed Data : Food Chem Toxicol. 2009 Sep ;47(9):2157-62. Epub 2009 Jun 6. PMID: 19501127
Article Published Date : Aug 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Lichens
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Caspase-8 activation, Caspase-9 Activation
Additional Keywords : Dose Response, Plant Extracts
[+]

Lichen metabolites showed various cytotoxic effects in a concentration-dependent manner against cancer cells. Feb 28, 2013

Pubmed Data : Phytother Res. 2013 Mar ;27(3):431-7. Epub 2012 May 25. PMID: 22628260
Article Published Date : Feb 28, 2013
Study Type : In Vitro Study
Additional Links
Substances : Lichens
Diseases : Breast Cancer, Cervical Cancer, Colon Cancer, Oxidative Stress
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation
Additional Keywords : Dose Response, Metabolites
[+]

Lion's mane induces programmed cell death in monocytic leukemia cells. Jun 01, 2011

Pubmed Data : Food Funct. 2011 Jun ;2(6):348-56. Epub 2011 Jun 8. PMID: 21779573
Article Published Date : Jun 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Infant Acute Monocytic Leukemia, Leukemia: Monocytic
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Major triterpenoids in Chinese hawthorn inhibited proliferation and induced apoptosis in MDA-MB-231 cancer cells.Jan 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Feb ;100:149-160. Epub 2016 Dec 23. PMID: 28025124
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Hawthorn, Ursolic Acid
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest, Cyclin D1 Down-Regulation
Additional Keywords : Antiproliferative, Breast Cancer: Triple Negative, Dose Response, Hawthorn, Ursolic Acid
[+]

Melatonin sensitizes the cisplatin-mediated growth suppression of liver cancer cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2017 ;7(1):13-27. Epub 2017 Jan 1. PMID: 28123844
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

MLAuNP possesses antiproliferative properties and induced apoptosis in A549 cells by activating alternate splicing of caspase-9.Feb 28, 2016

Pubmed Data : J Cell Biochem. 2016 Feb 29. Epub 2016 Feb 29. PMID: 26923760
Article Published Date : Feb 28, 2016
Study Type : In Vitro Study
Additional Links
Substances : Gold (nanoparticles), Moringa oleifera
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-9 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

Morus alba leaf lectin has possible antimetastatic effects by inducing anoikis in MCF-7 cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:34. Epub 2017 Feb 7. PMID: 28223935
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : White Mulberry
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Caspase-9 Activation, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Plant Extracts
[+]

Natural compounds present in oyster mushroom could modulate apoptosis and cell cycle pathways that are frequently blocked in human cancers.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Iran Med. 2015 May ;18(5):284-95. PMID: 25959910
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Mushrooms: All , Oyster Mushroom
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest, P21 Activation
[+]

Oridonin effectively inhibited cell proliferation and induced apoptosis in HCT-116 and LoVo cells in a concentration-dependent manner.Apr 30, 2015

Pubmed Data : Biomed Pharmacother. 2015 May ;72:125-34. Epub 2015 Apr 27. PMID: 26054686
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation, MicroRNA modulator
Additional Keywords : Dose Response
[+]

Resveratraol induces cell death in human ovarian cancer cells. Nov 01, 2010

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2010 Nov;30(11):2440-2. PMID: 21097399
Article Published Date : Nov 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Resveratrol could suppress hyperplasia of synovial cells, a critical factor of rheumatoid arthritis.Aug 10, 2010

Pubmed Data : Rheumatol Int. 2010 Aug 10. Epub 2010 Aug 10. PMID: 20697895
Article Published Date : Aug 10, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Arthritis: Rheumatoid
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Resveratrol induces programmed cell death in ovarian cancer cells. Jan 01, 2011

Pubmed Data : J Med Food. 2011 Jan-Feb;14(1-2):46-52. Epub 2010 Dec 27. PMID: 21186985
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Shikonin exhibited its anti-tumor activity against HGC-27 cells through inhibiting cell growth and promoting apoptosis by targeting mitochondrial-related signaling pathway.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 Apr-Jun;11(42):250-6. PMID: 25829762
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lithospermum erythrorhizon, Shikonin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation
[+]

Tetrahydrocurcumin is more effective than curcumin in inducing the apoptosis of H22 cells.Aug 01, 2017

Pubmed Data : Food Funct. 2017 Aug 2. Epub 2017 Aug 2. PMID: 28766664
Article Published Date : Aug 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

The green tea polyphenol EGCG enhances the anti-cancer activity of bortezomib in multiple myeloma cells. Dec 01, 2009

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2009 Dec;41(12):1018-26. PMID: 20011976
Article Published Date : Dec 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Tea
Diseases : Multiple Myeloma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Chemosensitizer
Additional Keywords : Drug: Bortezomib, Drug Synergy
[+]

These findings suggest that mango kernel extract has potential to be developed into a therapeutic mixture for treatment of breast cancers.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:45. Epub 2015 Mar 9. PMID: 25881293
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mango Seed
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, Redox Modulator
Additional Keywords : Dose Response
[+]

These results reveal that Taiwanofungus salmoneus could be a potential adjuvant chemotherapeutic agent.Dec 31, 2014

Pubmed Data : Int J Med Mushrooms. 2015 ;17(6):567-77. PMID: 26349514
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Medicinal Mushrooms, Mushrooms: All
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, Cell cycle arrest, Chemotherapeutic
Additional Keywords : Drug: Cisplatin, Plant Extracts
Problem Substances : Cisplatin
[+]

These results suggested that cucurbitacin E maybe used as a therapeutic agent in the treatment of human prostate cancer.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Jun ;13(6):4905-4910. Epub 2017 Apr 24. PMID: 28599494
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin E
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-9 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

Tualang honey has significant anticancer activity against human breast and cervical cancer cell lines.Mar 31, 2011

Pubmed Data : Food Chem Toxicol. 2011 Apr ;49(4):871-8. Epub 2010 Dec 16. PMID: 21167897
Article Published Date : Mar 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Tualang Honey
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cervical Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-7 Activation , Caspase-9 Activation
[+]

Tulsi extracts can effectively induce apoptosis in prostate cancer cells.Jun 30, 2015

Pubmed Data : J Med Food. 2015 Jul ;18(7):776-85. Epub 2015 Feb 18. PMID: 25692494
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Caspase-9 Activation
Additional Keywords : Plant Extracts
[+]

White tea extract showed high anti-proliferative activity against HT-29 cells, without being toxic to normal fibroblasts.Feb 14, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2015 Feb 15 ;169:401-10. Epub 2014 Jul 8. PMID: 25236244
Article Published Date : Feb 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : White Tea
Diseases : Colon Cancer, Colon Cancer: Prevention, DNA damage
Pharmacological Actions : Antioxidant, Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation
Additional Keywords : DNA Protective, Plant Extracts
[+]

Xanthohumol induces cell death in human malignant glioblastoma cells. Dec 27, 2011

Pubmed Data : J Nat Prod. 2011 Dec 27 ;74(12):2505-13. Epub 2011 Nov 23. PMID: 22111577
Article Published Date : Dec 27, 2011
Study Type : In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Glioblastoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

α-tomatine in pure form and in tomatine rich green tomatoes might prevent colon cancer.Jan 22, 2015

Pubmed Data : J Agric Food Chem. 2015 Jan 23. Epub 2015 Jan 23. PMID: 25614934
Article Published Date : Jan 22, 2015
Study Type : In Vitro Study
Additional Links
Substances : Tomato
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation

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