Cell cycle arrest

Name	AC	CK
Curcumin	122	145
Flavonoids	76	97
Resveratrol	49	57
Polyphenols	34	53
Sulforaphane	35	43
Berberine	34	41
Ginsenosides	35	39
Genistein	20	33
Cucurbitacin B	23	30
Lycopene	11	30
Quercetin	29	30
Apigenin	16	29
Licorice	22	27
Thymoquinone	18	26
Pterostilbene	16	21
Piperine	9	18
Xanthohumol	15	18
Fucoidan	16	17
Indole-3-Carbinol	13	17
Water: Deuterium Depleted	7	17
Garlic	15	16
Silibinin	7	16
Anthocyanins	12	15
Daidzein	11	15
Frankincense	7	15
Milk Thistle	6	15
Reishi Mushroom	11	15
Vitamin C	14	15
Honokiol	13	14
Kaempferol	14	14
Luteolin	13	14
Tanshinone IIA	13	14
Catechin	11	13
EGCG (Epigallocatechin gallate)	12	13
Myricetin	13	13
Naringenin	11	13
Piperlongumine	11	13
Caffeic Acid	3	12
Gingerol	11	12
Magnolol	7	12
Emodin	9	11
Fucoxanthin	9	11
Grape Seed Extract	7	11
Mulberry	5	11
Nobiletin	10	11
Oridonin	10	11
Vitamin E	10	11
Antrodia camphorata	4	10
Artemisinin	9	10
Caffeine	1	10
Huaier (Trametes robiniophila murr)	8	10
Isoflavones	8	10
Melatonin	10	10
Motherwort	1	10
Organosulfur Compounds	8	10
Phellinus Linteus	8	10
Progesterone	1	10
Stilbenes	9	10
Ursolic Acid	9	10
Astaxanthin	8	9
Baicalein	7	9
Bisdemethoxycurcumin	5	9
Curcumol	7	9
Dandelion	7	9
Dogwood	4	9
Ellagic Acid	4	9
Fisetin	9	9
Formononetin	7	9
Graviola	5	9
Isothiocyanates	9	9
Pomegranate	5	9
Sesamin	5	9
Tocotrienol: Gamma	5	9
Vitamin D	9	9
6-Shogaol	6	8
Amygdalin	6	8
Ashwagandha	7	8
Bee Propolis	7	8
Berbamine	5	8
Carnosic Acid	7	8
Cruciferous Vegetables	8	8
Green Tea	6	8
Isoliquiritigenin	7	8
Maitake Mushroom	6	8
Paeoniflorin	7	8
Phloretin	8	8
Proanthocyanidins	6	8
Rhubarb	4	8
Salvia miltiorrhiza	8	8
Shallot	6	8
Tetrahydrocurcumin	3	8
Wogonin	8	8
Andrographis	7	7
Artesunate	6	7
Benzyl isothiocyanate	5	7
Betulinic acid	7	7
Black Tea	7	7
Cannabidiol	6	7
Celastrol	6	7
Chaga Mushroom (Inonotus obliquus)	6	7
Chokeberry	3	7
Cordyceps Militaris	7	7
Cordyceps sinensis	4	7
Deguelin	7	7
Diosgenin	6	7
Ginger	5	7
Lemongrass	3	7
Moringa oleifera	5	7
Mushrooms: All	3	7
Shikonin	5	7
Tocotrienol: Delta	6	7
Adlay	6	6
Beta-Elemene	6	6
Caffeic acid phenethyl ester	5	6
Cannabinoids	5	6
Carrot	2	6
Chlorogenic Acid	5	6
Chrysin	5	6
Citral	2	6
Cucurbitacin E	6	6
Diosmin	4	6
Elecampane	6	6
Ginkgo biloba	5	6
Hesperidin	5	6
Homeopathic Medicine: All	5	6
Lignans	5	6
Manuka Honey	2	6
Oleanolic acid	5	6
Parthenolide	5	6
Piceatannol	6	6
Prickly Pear Cactus	5	6
Prunella vulgaris	4	6
Psychedelics:All	5	6
Zerumbone	6	6
Aloe Vera	4	5
Andrographolide	5	5
Apples	4	5
Arctigenin	1	5
Bee Venom	5	5
Bitter Melon	5	5
Blueberry	4	5
Cinnamon	5	5
Cucurbitacin D	4	5
Curcumin: Degradiation byproducts	1	5
Demethoxycurcumin	5	5
Evodiamine	4	5
Fiber	4	5
Gac	3	5
Garlic: Aged	1	5
Gynostemma	5	5
Lactoferrin	5	5
Lichens	4	5
Mangosteen	4	5
Medicinal Mushrooms	3	5
Nettle	4	5
Olive leaf extract	4	5
Panax Notoginseng	4	5
Pine Bark Extract	5	5
Rose	5	5
Soy	4	5
Spirulina	4	5
Sprouts	4	5
Tangeretin	5	5
Toona sinensis	3	5
Turmeric	5	5
Vitamin E: Gamma-tocotrienol	5	5
Vitamin K	5	5
Alpinia galanga	3	4
Apple Pectin	2	4
Babchi	3	4
Bai Zhu	3	4
Beans: All	3	4
Broccoli	4	4
Capsaicin	4	4
Carotenoids	4	4
Carvacrol	4	4
Chlorella (Algae)	3	4
Crocin	4	4
DHA (Docosahexaenoic Acid)	4	4
Delta-tetrahydrocannabinol (THC)	3	4
Diosmetin	4	4
Echinacea	3	4
Ferulic acid	4	4
Gallic Acid	3	4
Icariin	3	4
Inositol Hexaphosphate	3	4
Lotus	4	4
Mangiferin	3	4
Mistletoe	3	4
Neem	4	4
Nordihydroguaiaretic acid (NDGA)	2	4
Oleuropein	4	4
Oyster Mushroom	4	4
Pine Needle	4	4
Poria cocos	2	4
Puerarin	4	4
Rosemary	4	4
Rosmarinic acid	3	4
Sandalwood	4	4
Selenium	3	4
Shiitake Mushroom	3	4
Solanum nigrum (black nightshade)	3	4
Syrian rue	3	4
Urolithin A	3	4
Wheat Grass	3	4
Whey	3	4
acetyl-11-keto-beta-boswellic acid	4	4
Angelica	2	3
Apple Polyphenols	3	3
Asiatic Acid	3	3
Bacopa	3	3
Beta Sitosterol	3	3
Bromelain	2	3
Bufalin	3	3
Cannabinoids: Synthetic	2	3
Carnosol	2	3
Chrysanthemum Indicum	3	3
Citrus naringin	3	3
Collagen	2	3
Curcuminoids	3	3
Curry Leaves	2	3
Daisy	2	3
Dimethyl trisulfide (DMTS)	2	3
Eriodictyol	2	3
Eugenol	3	3
Fermented Foods and Beverages	3	3
Ginseng	3	3
Gold (nanoparticles)	3	3
Harmine	2	3
Horse Chestnut	3	3
Litchi	2	3
Magnolia	3	3
Nexrutine (Phellodendrom)	2	3
Passion Flower	2	3
Peony	2	3
Perilla	3	3
Phenethyl isothiocyanate	3	3
Pomegranate Peel	3	3
Propolis: Brazillian	3	3
Rosemaric Acid	3	3
Saffron	3	3
Seaweed: Brown	3	3
Sumac	2	3
Tannic Acid	3	3
Theaflavins	3	3
Vitamin E: delta-tocopherol	3	3
Walnut	3	3
Xanthones	3	3
Zataria multiflora	1	3
beta-Carotene	3	3
Allicin	2	2
Anthurium schlechtendalii	1	2
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	1	2
Antineoplastons	2	2
Apple	2	2
Astragaloside	2	2
Banaba	2	2
Barberry	2	2
Barley	1	2
Bergamot	2	2
Betel	2	2
Biochanin A	2	2
Bitter Orange	2	2
Black Bean	2	2
Black Cohosh	2	2
Black Pepper	1	2
Boswellia	1	2
Broccoli Sprouts	1	2
Burdock	2	2
Butyrate	2	2
Cannabis	2	2
Catechols	2	2
Chinese Skullcap	2	2
Cinnamaldehyde	2	2
Citrus Peel	2	2
Cranberry	2	2
Cyanidin 3-glucoside	2	2
Delphinidin	2	2
Diallyl sulfide	2	2
Dill	2	2
Eucalyptus	2	2
Fig	2	2
Fish Oil	1	2
Flaxseed	1	2
Fruit Peel	1	2
Fruit: All	2	2
Genipin	1	2
Ginseng (American)	2	2
Ginseng (Siberian)	2	2
Grape	2	2
Guava	2	2
Honey	2	2
Honeysuckle	2	2
Hydrogen: Molecular	1	2
Hydroxytyrosol	2	2
Indian Gooseberry	2	2
Isoquercitrin	1	2
Japanese mugwort	2	2
Lactococcus lactis	2	2
Ligustrazine	2	2
Lime	2	2
Lion's Mane (Hericium Erinaceus)	2	2
Lupeol	2	2
MSM (Methylsulfonylmethane)	2	2
Modified Arabinoxylan Rice Bran (MGN-3)	1	2
Modified Citrus Pectin	1	2
Mugwort	2	2
Mululuza	2	2
Myrrh	1	2
NAC (N-acetyl-L-cysteine)	1	2
Noni leaf extract	1	2
Olive	2	2
Paeonol	2	2
Palmitoylethanolamide	1	2
Panax Ginseng	1	2
Peanut	1	2
Probiotics	2	2
Punicalagin	2	2
Rhodiola (Tibetan Ginseng)	2	2
Rose Hips	2	2
Royal Jelly	2	2
Ruta Graveolens	2	2
Rutin	2	2
Safflower	2	2
Safranal	2	2
Saturated fatty acids	1	2
Sea buckthorn	2	2
Seaweed	2	2
Sesame Seeds	2	2
Sinomenine	2	2
Soy Protein	1	2
Stearic Acid (stearate)	1	2
Strawberry	1	2
Sweet Potato: Purple	1	2
Tea	2	2
Thymol	2	2
Tocotrienols	1	2
Tomato	1	2
Trichosanthes Kirilowii	1	2
Vanillin	2	2
Verbascoside	2	2
Vitamin A	2	2
Vitamin E: alpha tocopherol	2	2
Vitamin K2	2	2
Wasabi	2	2
Wheat Germ	2	2
18β-Glycyrrhetinic Acid	1	1
2-Methoxyestradiol	1	1
Agaricus Blazei	1	1
Agrimony	1	1
Aleurone	1	1
Algae	1	1
Alpha-Lipoic Acid	1	1
Asafoetida	1	1
Asparagus	1	1
Astragalus	1	1
Banana	1	1
Bergamot orange	1	1
Berries: All	1	1
Beta-Caryophyllene	1	1
Beta-glucan	1	1
Betaine	1	1
Bitter Apple	1	1
Brown Rice	1	1
Brussel sprouts	1	1
Cafestol	1	1
Camel Milk	1	1
Capparis spinosa (caper)	1	1
Carbon 60	1	1
Cardamonin	1	1
Carnosine	1	1
Cashew	1	1
Celery	1	1
Celery seed	1	1
Chicory	1	1
Chives	1	1
Citrus Triterpenoids	1	1
Citrus aurantium	1	1
Cleavers	1	1
Cocoa	1	1
Coffee	1	1
Copper	1	1
Coptidis rhizoma	1	1
Coriolus versicolor	1	1
Corn Silk	1	1
Corn: Purple	1	1
Cryptomeria japonica	1	1
Cryptoxanthin	1	1
Curcuma Comosa	1	1
Curry Tree	1	1
D-Limonene	1	1
Decursin	1	1
Deuterium (heavy water)	1	1
Dragon Fruit	1	1
EPA (Eicosapentaenoic Acid)	1	1
Egg	1	1
Elm tree	1	1
Epimedium	1	1
Evening Primrose Oil	1	1
False Black Pepper	1	1
Fennel	1	1
Fenugreek	1	1
Flavan-3-ols	1	1
Flaxseed Oil	1	1
Folate	1	1
Galbanic Acid	1	1
Garcinia dulcis	1	1
Garcinia hanburyi	1	1
Geranium	1	1
Ginseng (Korean)	1	1
Glycitein	1	1
Glycyrrhiza uralensis	1	1
Glycyrrhizin	1	1
Goji	1	1
Gold	1	1
Goldenseal	1	1
Goldenthread	1	1
Gotu Kola	1	1
Grapefruit	1	1
Green Coffee Bean	1	1
Guduchi	1	1
HDTIC-1	1	1
HDTIC-2	1	1
Hawthorn	1	1
Helenalin	1	1
Hemp Seed	1	1
Hibiscus	1	1
Hibiscus sabdariffa	1	1
Hops	1	1
Hydrangea	1	1
Hydrogen Peroxide	1	1
Indigo Naturalis	1	1
Iodine	1	1
Jujube	1	1
Juniper	1	1
Kava Kava	1	1
Kimchi	1	1
Lactobacillus gasseri	1	1
Lactobacillus paracasei	1	1
Lactobacillus plantarum	1	1
Lactobacillus rhamnosus	1	1
Lactobacillus rhamnosus GG	1	1
Leek	1	1
Lemon Balm	1	1
Lemon Myrtle	1	1
Lettuce	1	1
Lithospermum erythrorhizon	1	1
Lobelia	1	1
Lutein	1	1
Lychee	1	1
Mango	1	1
Molasses	1	1
Mustard Oil	1	1
Nigella sativa (aka Black Seed)	1	1
Noni	1	1
Oats	1	1
Olive Oil	1	1
Onion	1	1
Orange	1	1
Oregano	1	1
Orthosiphon	1	1
Oyster Mushroom: Golden	1	1
P-Coumaric Acid	1	1
Palash	1	1
Palm Oil	1	1
Papaya	1	1
Parsley	1	1
Patchouli	1	1
Pau D'Arco	1	1
Pea	1	1
Peach	1	1
Pelargonium sidoides	1	1
Phyllanthus emblica	1	1
Pinus Massoniana Bark	1	1
Pistachio nut	1	1
Pleurotus nebrodensis	1	1
Propolis: Bee	1	1
Raspberry	1	1
Red Marine Algae	1	1
Red Wine Extract	1	1
Rice Bran	1	1
Rooibos	1	1
Rose: Essential Oil	1	1
Roselle	1	1
S-Adenosylmethionine (SAMe)	1	1
Sage	1	1
Schisandra	1	1
Scutellaria barbata	1	1
Sea Cucumber	1	1
Sembung Leaf	1	1
Sesamol	1	1
Shilajit	1	1
Silver (nanoparticles)	1	1
Soursop	1	1
Spikenard	1	1
Stevia	1	1
Thistle	1	1
Toad	1	1
Tongkat Ali	1	1
Traditional Chinese Medicine: Mylabris	1	1

[+]

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID: 23943362

This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.Dec 31, 2010

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Pubmed Data : Genom Data. 2015 Sep 1 ;5:189-191. PMID: 26309812

Article Published Date : Aug 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Mushrooms: All

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Epigenetic Modification In Cancer, Gene Expression Regulation

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Pubmed Data : Sci Rep. 2016 Aug 8 ;6:30917. Epub 2016 Aug 8. PMID: 27498973

Article Published Date : Aug 07, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Polyphenols, Strawberry

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest, Chemopreventive

Additional Keywords : Dose Response

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Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.Feb 12, 2016

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Pubmed Data : Mol Med Rep. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27035431

Article Published Date : Mar 29, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Gallbladder Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

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Pubmed Data : Planta Med. 2014 Apr ;80(6):452-7. Epub 2014 Mar 31. PMID: 24687742

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Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(6):2307-12. PMID: 25824755

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumol

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Dose Response, Selective Cytotoxicity

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Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion.Apr 13, 2021

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Pubmed Data : Cancers (Basel). 2024 Jan 16 ;16(2). Epub 2024 Jan 16. PMID: 38254868

Article Published Date : Jan 15, 2024

Study Type : Animal Study

Additional Links

Substances : Organosulfur Compounds

Diseases : Head and Neck Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.Mar 26, 2017

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Pubmed Data : Acta Pharmacol Sin. 2017 Mar 27. Epub 2017 Mar 27. PMID: 28344324

Pubmed Data : Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Feb 28 ;41(1):43-52. PMID: 30837041

Article Published Date : Feb 27, 2019

Study Type : Animal Study

Additional Links

Substances : Garlic, Organosulfur Compounds

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

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Pubmed Data : Cancers (Basel). 2019 Oct 5 ;11(10). Epub 2019 Oct 5. PMID: 31590367

Article Published Date : Oct 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Cancer Glycolysis, Chemotherapeutic Synergy: Gemcitabine

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Emodin inhibits the proliferation of papillary thyroid carcinoma by activating AMPK .Sep 30, 2021

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Pubmed Data : PLoS One. 2012 ;7(8):e43064. Epub 2012 Aug 8. PMID: 22905202

Article Published Date : Dec 31, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Grape Seed Extract

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest

Additional Keywords : Plant Extracts, Proanthocyanidins

[+]

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Pubmed Data : Biomed Pharmacother. 2017 Dec ;96:120-128. Epub 2017 Sep 30. PMID: 28972884

Lipophilic grape seed proanthocyanidin inhibited the growth of PC3-derived mouse xenografts by inhibiting tumor cell proliferation and inducing apoptosis.Jan 08, 2019

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Pubmed Data : J Agric Food Chem. 2019 Jan 9 ;67(1):229-235. Epub 2018 Dec 28. PMID: 30562012

Article Published Date : Jan 08, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Grape Seed Extract, Proanthocyanidins

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Maitake mushroom and its active fraction inhibit hepatoma growth by inducing autophagy and apoptosis.Mar 23, 2016

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Pubmed Data : Exp Biol Med (Maywood). 2016 Mar 24. Epub 2016 Mar 24. PMID: 27013543

Article Published Date : Mar 23, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Maitake Mushroom

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest

Additional Keywords : Plant Extracts

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Mangiferin may be considered a potential antineoplastic drug for the future treatment of cancer.Mar 31, 2016

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Pubmed Data : Mol Med Rep. 2016 Apr ;13(4):3423-32. Epub 2016 Feb 29. PMID: 26935347

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Pubmed Data : Sci Rep. 2016 ;6:20417. Epub 2016 Feb 3. PMID: 26838546

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Mulberry

Diseases : Bladder Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemopreventive

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Plant Extracts

[+]

Murraya koenigii and its flavonoid compounds which act as proteasome inhibitors.May 19, 2016

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Pubmed Data : Anticancer Agents Med Chem. 2016 May 20. Epub 2016 May 20. PMID: 27198988

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Pubmed Data : Front Nutr. 2022 ;9:839364. Epub 2022 Mar 3. PMID: 35308267

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Benzo[a]pyrene-induced Toxicity

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Gastroprotective

Problem Substances : Benzo(a)pyrene

[+]

Prunella vulgaris has potential as a lung cancer chemopreventive agent.Dec 31, 2009

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Pubmed Data : Asian Pac J Cancer Prev. 2010 ;11(5):1355-8. PMID: 21198292

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Pubmed Data : J Biomol Struct Dyn. 2021 Jan 22:1-23. Epub 2021 Jan 22. PMID: 33480316

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Pubmed Data : Int J Mol Sci. 2020 Dec 26 ;22(1). Epub 2020 Dec 26. PMID: 33375383

Article Published Date : Dec 25, 2020

Study Type : Animal Study

Additional Links

Substances : Sumac

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Plant Extracts

[+]

Synergetic delivery of artesunate and isosorbide 5-mononitrate with reduction-sensitive polymer nanoparticles for ovarian cancer.Nov 04, 2022

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Pubmed Data : J Nanobiotechnology. 2022 Nov 5 ;20(1):471. Epub 2022 Nov 5. PMID: 36335352

Article Published Date : Nov 04, 2022

Study Type : Animal Study

Additional Links

Substances : Artesunate

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

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View the Evidence: 1701 Abstracts with Cell cycle arrest Research

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Lycopene inhibits liver cancer cell growth.Jan 01, 2005

Chinese motherwort has cytotoxicity against human breast cancer cells that is non-apoptic and estrogen receptor independent. Mar 18, 2009

Curcuminoids could be coadjuvants that might help fight breast cancer upon regular consumption.May 31, 2021

Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients.Jun 17, 2022

Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.Feb 16, 2015

The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.Dec 31, 2012

An ethanolic extract of T. camphoratus treatment further enhanced the tumor suppression efficiency of cisplatin and doxorubicin.Dec 31, 2014

Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.Nov 30, 2013

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Arctigenin is able to inhibit cell proliferation and may induce apoptosis and cell cycle arrest at the G0/G1 phase in glioma cells.Jan 31, 2017

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest. Mar 31, 2007

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

Graviola extracts inhibited the proliferation of HL-60 cells in a concentration dependent manner and induced apoptosis.Dec 31, 2013

Human bladder cancer cells and immortalized normal bladder cells were studied using Frankincense oil; Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Dec 31, 2008

M. nigra may be a novel candidate for the development of new natural product based therapeutic agents against prostate cancer.Jan 31, 2017

Magnolol induced cell cycle arrest and promoted apoptosis in gallbladder carcinoma cells by regulating the p53 signaling pathway.Sep 30, 2015

P. granatum extracts had cytotoxic and apoptotic effects on human U266 multiple myeloma cells via disruption of mitochondrial membrane potential and increasing cell cycle arrest.Aug 28, 2015

Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.Dec 31, 2014

Piperine was found to exert selective cytotoxic effects against A549 cells in a dose-dependent manner.Mar 31, 2014

Pterostilbene might be used to modulate two anticancer compounds in well-defined sets of GBM patients.Nov 07, 2016

Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.Dec 14, 2016

Tetrahydrocurcumin exhibited significant cell growth inhibition by inducing MCF-7 cells to undergo mitochondrial apoptosis and G2/M arrest.Apr 30, 2014

The present study results indicated that human bladder cancer T-24 cells are highly sensitive to growth inhibition by apigenin.Dec 31, 2014

The synergistic antiproliferative action of combined γ-tocotrienol and sesamin treatment in mouse and human mammary cancer cells was cytostatic, not cytotoxic.Dec 31, 2012

These results increase knowledge of the effect of gastrointestinal digestion on the biological effect of honey against colorectal cancer.Jan 09, 2020

These results provide important new data for ellagic acid in anti-colorectal carcinoma research.Jan 31, 2017

These results suggest that HEABG may be effective in the prevention and treatment of endometriosis in humans.Jun 30, 2013

This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.Dec 31, 2010

This study demonstrates that sulforaphane targets multiple signaling pathways to suppress ovarian cancer in vitro and in vivo.Nov 01, 2018

Thymoquinone promotes pancreatic cancer cell death and reduction of tumor size.Dec 31, 2015

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.Jan 09, 2017

Amentoflavone induces caspase-dependent/-independent apoptosis and dysregulates cyclin-dependent kinase-mediated cell cycle in colorectal cancer.Apr 30, 2023

Berbamine exerts an anti-oncogenic effect on pancreatic cancer.May 08, 2022

Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancer.Sep 20, 2022

Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells.Feb 20, 2023

Cordycepin enhances radiosensitivity to induce apoptosis through cell cycle arrest, caspase pathway and ER stress in MA-10 mouse Leydig tumor cells.Dec 31, 2021

Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells.Sep 30, 2022

Fucoxanthin inactivates the PI3K/Akt signaling pathway to mediate malignant biological behaviors of non-small cell lung cancer.Jul 14, 2022

Glabridin inhibits urothelial bladder carcinoma cell growth.Sep 12, 2022

In-vitro and in-vivo investigation of amygdalin, metformin, and combination of both against doxorubicin on hepatocellular carcinoma.Nov 14, 2021

Moringa oleifera L. leaf extract induces cell cycle arrest and mitochondrial apoptosis in Dalton's Lymphoma.Oct 24, 2022

Pachymic acid inhibits growth and induces cell cycle arrest and apoptosis in gastric cancer SGC-7901 cells.Jul 31, 2018

Promotion of ROS-mediated apoptosis, G2/M arrest, and autophagy by naringenin in non-small cell lung cancer.Dec 31, 2023

This study demonstrated the successful inhibitory effect of AP-ZEONE on metastatic breast cancer cells.Dec 31, 2021

"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."Mar 01, 2005

6-Gingerol induces cell-cycle G1-phase arrest through AKT-GSK 3β-cyclin D1 pathway in renal-cell carcinoma.Dec 11, 2019

A combined mixture of medicinal mushrooms and P. ginseng root extracts could be an adjuvant treatment in human colorectal cancer.Aug 31, 2017

A compound from Allium hirtifolium could inhibit growth of MCF-7 and MDA-MB-231 cells through cell cycle arrest and apoptosis induction.Aug 31, 2017

A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.Aug 07, 2016

Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.Feb 12, 2016

Administration of quercetin at 15mg/kg body weight resulted in a ~70% reduction in tumor growth.Dec 31, 2015

Allomelanins suppress the tumor cell growth in vitro and in vivo.Aug 01, 1997

Aloe vera gel could suppress colitis-related colon carcinogenesis.Sep 29, 2016

An ethanol extract of Shitake (Lentinula elodes) selectively kills skin cancer cells in mice. Mar 18, 2005

An ethanol extract of sporoderm-broken spores of G. lucidum suppressed the growth of human lung cancer.Sep 30, 2016

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.Jan 29, 2017

Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo.Sep 14, 2017

Anthocyanin enriched sweet potatoes may protect against colorectal cancer by inducing cell-cycle arrest, antiproliferative, and apoptotic mechanisms.Oct 31, 2013

Anti-cancer effect of cordycepin on FGF9-induced testicular tumorigenesis. Nov 05, 2020

Anticancer activities of parthenolide in primary effusion lymphoma preclinical models.Jun 07, 2021

Antitumor activity of fucoidan against diffuse large B cell lymphoma in vitro and in vivo.Oct 31, 2015

Antrodia camphorata extract, when combined with anti-tumor agents, showed adjuvant antiproliferative effects on multi-drug resistant hepatoma. Aug 13, 2008

Apigenin may act as a chemotherapeutic agent for cervical cancer treatment.Apr 03, 2022

Apple total triterpenoid content induced apoptosis in MDA-MB-231 cells.Sep 18, 2012

Artemisinin may be suitable for the treatment of gallbladder cancer.Mar 29, 2016

As mono-therapy the natural isoflavone genistein has a powerful therapeutic effect in vivo on A431 and Colo205 tumors.Apr 06, 2016

Astaxanthin can inhibit proliferation and induce apoptosis and cell cycle arrest in mice H22 hepatoma cells in vitro and in vivo.Dec 31, 2015

Baicalein exerts potent S phase cell cycle arrest and pro-apoptotic effects in HCT-116 cells.Oct 31, 2015

Baicalein may be a potent reagent for acute megakaryoblastic leukemia (AMKL) therapy.Dec 31, 2015

Benzyl isothiocyanate induces apoptosis and inhibits tumor growth in canine mammary carcinoma.Dec 31, 2019

Cell cycle arrest

View the Evidence:
1701 Abstracts with Cell cycle arrest Research