Chemosensitizer

Name	AC	CK
Curcumin	117	133
Ginsenosides	39	73
Flavonoids	38	46
Resveratrol	39	45
Quercetin	30	37
Vitamin C	29	36
EGCG (Epigallocatechin gallate)	25	35
Thymoquinone	21	29
Melatonin	23	28
Tanshinone IIA	27	28
Shikonin	23	27
Ursolic Acid	16	27
Berberine	24	26
Sulforaphane	23	26
Beta-Elemene	22	25
Silibinin	11	25
Emodin	18	23
Genistein	15	22
Fucoidan	10	21
Artesunate	13	18
Pterostilbene	9	18
Piperlongumine	15	17
Wogonin	10	17
Apigenin	15	16
Astragaloside	13	15
Piperine	9	15
Vitamin D	12	14
Capsaicin	8	13
Lotus	12	13
Cucurbitacin B	8	12
Curcumol	10	12
Bee Venom	11	11
Betulinic acid	9	11
Hesperidin	7	11
Luteolin	10	11
Naringenin	8	11
Reishi Mushroom	7	11
Amurensin G	2	10
Caffeine	1	10
Cannabidiol	8	10
Catechin	5	10
Crocin	7	10
Gingerol	4	10
Ginseng	2	10
Honokiol	10	10
Olive leaf extract	1	10
Puerarin	6	10
Fucoxanthin	9	9
Green Tea	4	9
Indole-3-Carbinol	6	9
Nobiletin	8	9
Organosulfur Compounds	6	9
Parthenolide	9	9
Polyphenols	9	9
Rutin	7	9
Turmeric	5	9
6-Shogaol	4	8
Bufalin	7	8
Chrysin	6	8
Cordyceps Militaris	7	8
Gold (nanoparticles)	7	8
Oridonin	6	8
Astaxanthin	6	7
Baicalein	4	7
Caffeic acid phenethyl ester	7	7
Celastrol	6	7
Ellagic Acid	5	7
Formononetin	5	7
Gynostemma	2	7
Lycopene	5	7
Panax Notoginseng	2	7
Biochanin A	4	6
Carotenoids	5	6
DHA (Docosahexaenoic Acid)	6	6
Demethoxycurcumin	5	6
Elecampane	5	6
Garlic	2	6
Ginger	5	6
Isothiocyanates	4	6
Kaempferol	5	6
Lupeol	5	6
Mistletoe	4	6
Myricetin	6	6
Pomegranate	4	6
Tangeretin	6	6
Triptolide	6	6
Vitamin E	5	6
Xanthohumol	6	6
Andrographis	4	5
Andrographolide	4	5
Antrodia camphorata	1	5
Arctigenin	5	5
Berbamine	4	5
Bromelain	4	5
Cannabinoids	4	5
Carbon 60	4	5
Deguelin	4	5
Genipin	3	5
Ginkgo biloba	5	5
Huaier (Trametes robiniophila murr)	1	5
Isoflavones	4	5
Mangiferin	3	5
Oleuropein	4	5
Paeoniflorin	4	5
Panaxadiol	1	5
Phenethyl isothiocyanate	4	5
Salvia miltiorrhiza	5	5
Vitamin E: Gamma-tocotrienol	5	5
White Mulberry	1	5
Ashwagandha	4	4
Bisdemethoxycurcumin	3	4
Cardamonin	3	4
Curcuminoids	3	4
Dandelion	3	4
Eugenol	4	4
Fenugreek	3	4
Fisetin	4	4
Isoliquiritigenin	3	4
Lactobacillus rhamnosus	2	4
Lactoferrin	3	4
Mulberry	4	4
Oleanolic acid	3	4
Paprika	3	4
Phellinus Linteus	4	4
Rosemaric Acid	4	4
Saikosaponin	4	4
Selenium	3	4
Tocotrienol: Gamma	3	4
Tripterygium wilfordii	4	4
Zerumbone	3	4
beta-Carotene	4	4
Allicin	3	3
Anthocyanins	3	3
Apple	2	3
Asiatic Acid	3	3
Bee Propolis	3	3
Beet	2	3
Beta-Caryophyllene	2	3
Chrysanthemum Indicum	2	3
Citrus naringin	2	3
Delphinidin	2	3
Diosgenin	2	3
Galbanic Acid	2	3
Gallic Acid	3	3
Horse Chestnut	3	3
Lemongrass	2	3
Licorice	3	3
Magnolol	3	3
Mangosteen	2	3
Nettle	3	3
Piceatannol	2	3
Red Clover	2	3
Sesamol	2	3
Sinomenine	3	3
Stilbenes	2	3
Tannic Acid	2	3
Tea	2	3
Theaflavins	3	3
Tocotrienol: Delta	3	3
Vitamin K	3	3
Alpha-Lipoic Acid	2	2
Alpinia galanga	1	2
Artemisinin	2	2
Barberry	1	2
Broccoli	1	2
Broccoli Sprouts	2	2
Butterfly Pea	1	2
Caffeic Acid	2	2
Cannabinoids: Synthetic	1	2
Carnosic Acid	2	2
Carvacrol	1	2
Chinese Skullcap	2	2
Chlorogenic Acid	2	2
Cholesterol	1	2
Cinnamic acid	1	2
Crocetin	2	2
Cucurbitacin E	1	2
Cysteine (see N-Acetylcysteine)	1	2
Dimethyl trisulfide (DMTS)	1	2
EPA (Eicosapentaenoic Acid)	2	2
Echinacea	1	2
Fermented Foods and Beverages	2	2
Fish Oil	1	2
Geraniol	2	2
Ginseng (Korean)	2	2
Glycyrrhizin	2	2
Goji	2	2
Grape	2	2
Honey	2	2
Kahweol	2	2
Lignans	2	2
Long Pepper	1	2
Lutein	2	2
Modified Arabinoxylan Rice Bran (MGN-3)	2	2
NAC (N-acetyl-L-cysteine)	2	2
Nordihydroguaiaretic acid (NDGA)	2	2
Onion	1	2
Paeonol	1	2
Pantothenic Acid (Vitamin B-5)	1	2
Phloretin	2	2
Prunella vulgaris	1	2
Saffron	2	2
Sesame Seeds	1	2
Shiitake Mushroom	1	2
Soup	1	2
Soy	1	2
Sprouts	1	2
Sweet Orange	1	2
Tomatidine	1	2
Urolithin A	1	2
Verbascoside	2	2
Wasabi	1	2
Zeaxanthin	1	2
Acerola	1	1
Adlay	1	1
African Basil	1	1
Aloe Vera	1	1
Amygdalin	1	1
Antheraxanthin	1	1
Apple: Golden Delicious	1	1
Artichoke	1	1
Asafoetida	1	1
Bergamot	1	1
Beta Sitosterol	1	1
Betel	1	1
Bioflavonoids	1	1
Birch	1	1
Bixin	1	1
Bloodroot	1	1
Burdock	1	1
Cafestol	1	1
Camptothecin	1	1
Cannabis	1	1
Canthaxanthin	1	1
Capsorubin	1	1
Carnosine	1	1
Carnosol	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chia	1	1
Citrus Triterpenoids	1	1
Cleistocalyx Operculatus	1	1
Coenzyme Q10	1	1
Cranberry	1	1
Cucurbitacin D	1	1
Cyanidin	1	1
DIM (3,3'-diindolylmethane)	1	1
Daidzein	1	1
Damnacanthal	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Diosmetin	1	1
Dopa bean	1	1
Erucin	1	1
Evening Primrose Oil	1	1
Farnesiferol A	1	1
Fennel	1	1
Ferula Persica	1	1
Ferula Szowitsiana	1	1
Ferulic acid	1	1
Flavan-3-ols	1	1
Flaxseed	1	1
Flaxseed Oil	1	1
Folic Acid	1	1
Frankincense	1	1
Ginseng (American)	1	1
Glucosamine	1	1
Grape Seed Extract	1	1
Grapefruit	1	1
Guarana	1	1
Harmine	1	1
Hawthorn	1	1
Hedyotis corymbosa	1	1
Hedyotiscone A	1	1
Icariin	1	1
Japanese Raisin Tree	1	1
Kiwifruit	1	1
Lactobacillus gasseri	1	1
Lactobacillus paracasei	1	1
Lactobacillus plantarum	1	1
Lactobacillus rhamnosus GG	1	1
Ligustrazine	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Lobelia	1	1
Loquat	1	1
MSM (Methylsulfonylmethane)	1	1
Maca	1	1
Mango	1	1
Manuka Honey	1	1
Medicinal Mushrooms	1	1
Milk: Fermented	1	1
Nexrutine (Phellodendrom)	1	1
Nicotinamide	1	1
Nigella sativa (aka Black Seed)	1	1
Oat Bran	1	1
Oleocanthal	1	1
Omega-3 Fatty Acids	1	1
Oolong tea	1	1
Orange	1	1
Patchouli	1	1
Peony	1	1
Perilla	1	1
Persimmon	1	1
Phyllanthus emblica	1	1
Piperidines	1	1
Poria cocos	1	1
Prickly Pear Cactus	1	1
Proanthocyanidins	1	1
Pycnogenol (Pine Bark)	1	1
Red Sage	1	1
Rhubarb	1	1
Riboflavin (Vitamin B-2)	1	1
Rice Bran	1	1
Rosemary	1	1
Royal Jelly	1	1
S-Adenosylmethionine (SAMe)	1	1
Sakuranetin	1	1
Sea buckthorn	1	1
Silymarin	1	1
Spirulina	1	1
Stigmasterol	1	1
Tabebuia	1	1
Tetrahydrocurcumin	1	1
Thyme	1	1
Tocotrienols	1	1
Vanillin	1	1
Vinpocetine	1	1
Vitamin A	1	1
Vitamin B-6	1	1
Vitamin C: Intravenous	1	1
Vitamin E: alpha tocopherol	1	1
Vitamin K2	1	1
Vitex negundo	1	1
Vitexins	1	1
Wheat Grass	1	1
White Button Mushroom	1	1
Xanthones	1	1
Zataria multiflora	1	1
Zinc	1	1
Zyflamend	1	1
acetyl-11-keto-beta-boswellic acid	1	1

[+]

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:630825. Epub 2021 Mar 18. PMID: 33815097

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Ginsenosides

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Angiogenesis Inhibitors, Chemoprotective Agents, Chemosensitizer

[+]

"Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer."Feb 28, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Expert Opin Ther Targets. 2016 Jan ;20(1):7-18. Epub 2015 Dec 15. PMID: 26568207

Article Published Date : Dec 31, 2015

Study Type : Animal Study, Human In Vitro

Additional Links

Diseases : Esophageal Cancer

Pharmacological Actions : Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK, Anti-metastatic, Apoptotic, Chemosensitizer

[+]

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Fitoterapia. 2018 Jan ;124:42-48. Epub 2017 Oct 12. PMID: 29031537

Article Published Date : Dec 31, 2017

Study Type : Human In Vitro

Additional Links

Substances : Silibinin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Colon Cancer

Pharmacological Actions : Chemosensitizer, Glucose transporter-1 (GLUT1) expression down-regulation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.Oct 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Baicalein enhances cisplatin sensitivity in cervical cancer cells by promoting cuproptosis through the Akt pathway.Sep 30, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2023 Jun ;114:154780. Epub 2023 Mar 21. PMID: 37004402

Article Published Date : May 31, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Breast Cancer, Cancers: Drug Resistant, DNA damage

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Lipid-based nanoparticle formulation of diallyl trisulfide chemosensitizes the growth inhibitory activity of doxorubicin in colorectal cancer.Mar 27, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Sci. 2019 Jan ;110(1):389-400. Epub 2018 Dec 14. PMID: 30431207

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Cancers: Drug Resistant, Glioblastoma

Pharmacological Actions : Anti-metastatic, Chemosensitizer

[+]

6-Gingerol is a potent inducer of p53 reactivation in HPV positive cervical cancer cells through proteasome inhibition.Nov 24, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Antineoplaston A10 works synergistically with conventional chemotherapy in human liver cancer transplanted to animals.May 01, 1992

Click here to read the entire abstract

Pubmed Data : Jpn J Cancer Res. 1992 May ;83(5):527-31. PMID: 1377669

Article Published Date : May 01, 1992

Study Type : Animal Study

Additional Links

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

Antitumor effect of epigallocatechin gallate and vincristine in mice with L5178Y lymphoma.Nov 01, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Res. 2017 Nov 27. Epub 2017 Nov 27. PMID: 29180474

Article Published Date : Nov 26, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Melanoma

Pharmacological Actions : Chemosensitizer, Chemotherapeutic

[+]

Ascorbic acid chemosensitizes colorectal cancer cells and synergistically inhibits tumor growth.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Physiol. 2018 ;9:911. Epub 2018 Jul 23. PMID: 30083105

Article Published Date : Dec 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Colorectal Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Oxaliplatin

[+]

Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progressionOct 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Appl Pharmacol. 2019 Sep 15 ;379:114662. Epub 2019 Jul 10. PMID: 31301315

Article Published Date : Sep 14, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bufalin

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

[+]

Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.Jan 25, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2013 Feb ;5(2):641-644. Epub 2012 Nov 22. PMID: 23419988

Article Published Date : Jan 31, 2013

Study Type : Animal Study

Additional Links

Substances : Butterfly Pea

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

Cholesterol derived from LDL acts as a chemosensitizer in multidrug resistant lymphoblastic leukemia cells.Oct 01, 2007

Click here to read the entire abstract

Pubmed Data : Biochem Cell Biol. 2007 Oct;85(5):638-46. PMID: 17901905

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Cholesterol

Diseases : Acute lymphoblastic leukemia (ALL), Cancers: Multi-Drug Resistant, Leukemia: T-cell acute Lymphoblastic

Pharmacological Actions : Chemosensitizer

[+]

Chrysanthemum indicum could enhance the anti-cancer activity of bleomycin and reduce the its induced pulmonary injury in H22 tumor-bearing mice.Feb 23, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Deguelin may represent a novel and effective chemo-agent against head and neck squamous cell carcinoma.Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Mar 29 ;7(13):16158-71. PMID: 26930714

Article Published Date : Mar 28, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cancers: Drug Resistant, Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, MicroRNA modulator

Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: 5-flourouracil

[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Formononetin regulates multiple oncogenic signalling cascades and enhances sensitivity to bortezomib in a multiple myeloma mouse model.Jul 06, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2019 Jul 7 ;9(7). Epub 2019 Jul 7. PMID: 31284669

Article Published Date : Jul 06, 2019

Study Type : Animal Study

Additional Links

Substances : Formononetin

Diseases : Multiple Myeloma

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

Functional combination of resveratrol and tamoxifen to overcome tamoxifen-resistance in breast cancer cells.Jun 28, 2024

Click here to read the entire abstract

Pubmed Data : Arch Pharm (Weinheim). 2024 Jun 29:e2400261. Epub 2024 Jun 29. PMID: 38943449

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2020 Dec ;20(6):374. Epub 2020 Oct 21. PMID: 33154772

Article Published Date : Nov 30, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Genipin

Diseases : Lung Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Genipin enhances the therapeutic effects of oxaliplatin by upregulating BIM in colorectal cancer.Feb 19, 2019

Click here to read the entire abstract

Pubmed Data : Mol Cancer Ther. 2019 Feb 20. Epub 2019 Feb 20. PMID: 30787174

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Drug: Oxaliplatin, Natural Substance/Drug Synergy

[+]

Mangiferin shows synergistic anticancer activity with cisplatin.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2019 Nov 26 ;67:153141. Epub 2019 Nov 26. PMID: 31884406

Article Published Date : Nov 25, 2019

Study Type : Animal Study

Additional Links

Substances : Nobiletin

Diseases : Cancers: Multi-Drug Resistant, Lung Cancer

Pharmacological Actions : Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

Novel pomegranate-nanoparticles ameliorate cisplatin-induced nephrotoxicity and improves cisplatin anti-cancer efficacy.Feb 27, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Mol Med Rep. 2014 Nov ;10(5):2535-41. Epub 2014 Sep 5. PMID: 25189132

Article Published Date : Oct 31, 2014

Study Type : Animal Study

Additional Links

Substances : Puerarin

Diseases : Esophageal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Drug: 5-flourouracil, Natural Substance/Drug Synergy

[+]

Puerarin enhances the anti-tumor effect of cisplatin on drug-resistant A549 cancer.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Biol Sci. 2021 ;17(13):3595-3607. Epub 2021 Aug 19. PMID: 34512168

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Rutin

Diseases : Liver Cancer

Pharmacological Actions : Autophagy Inhibitors, Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: Sorafenib

[+]

Rutin enhances the cisplatin-mediated antitumor activity and cytotoxicity against Dalton's lymphoma cells.Aug 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Adv Pharm Bull. 2021 Sep ;11(4):746-754. Epub 2020 Aug 5. PMID: 34888222

Article Published Date : Aug 31, 2021

Study Type : Animal Study

Additional Links

Substances : Rutin

Diseases : Dalton's Ascitic Lymphoma

Pharmacological Actions : Chemoprotective Agents, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Sensitization to anoikis by pygenic acid A could be used as a new therapeutic strategy to control the metastasis of breast cancer.Nov 09, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

The combination of TRAIL and cannabidiol decreased tumor growth in xenograft models.May 08, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2019 May 9 ;11(5). Epub 2019 May 9. PMID: 31075907

Article Published Date : May 08, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

The discovery of IL-12-induced CB2 overexpression in thyroid cancer cells may offer a new target for anaplastic thyroid cancer treatmentJan 31, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biosci Rep. 2018 Dec 21 ;38(6). Epub 2018 Dec 11. PMID: 30420490

Article Published Date : Dec 20, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Cancers: Drug Resistant, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

[+]

These results suggest that the combination of SK and gemcitabine may be a promising chemotherapy regimen for pancreatic cancer.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Transl Res. 2017 ;9(12):5507-5517. Epub 2017 Dec 15. PMID: 29312502

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

These results suggested that quercetin and cisplatin synergistically increased cellular toxicity in breast cancer cells.Jun 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ethnopharmacol. 2019 Oct 5 ;242:111699. Epub 2019 Apr 18. PMID: 31005632

Article Published Date : Oct 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Formononetin, Isoflavones

Diseases : Gliomas

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

This study highlights the potential therapeutic usefulness of curcumin as an adjunct in patients with chemoresistant advanced CRC. Feb 28, 2015

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2015 Mar ;36(3):355-67. Epub 2015 Feb 4. PMID: 25653233

Wogonin and 5-fluorouracil combination treatment caused a significant growth inhibition of human tumor xenografts in vivo.Jul 31, 2013

Click here to read the entire abstract

Pubmed Data : Biochem Cell Biol. 2013 Aug ;91(4):221-9. Epub 2013 Feb 14. PMID: 23859016

Article Published Date : Jul 31, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Wogonin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors

Additional Keywords : Drug: 5-flourouracil, Natural Substance/Drug Synergy, Plant Extracts

[+]

Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Int J Biol Macromol. 2021 Nov 3. Epub 2021 Nov 3. PMID: 34742847

Click any topic below to filter + focus research

View the Evidence: 1254 Abstracts with Chemosensitizer Research

Limited to Members Only

Currently Available Sorting Options

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

"Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer."Feb 28, 2011

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

Leaf extract from european olive post-transcriptionally suppresses the epithelial-mesenchymal transition and sensitizes gastric cancer cells to chemotherapy.Dec 31, 2023

6-shogaol, 6-gingerol and pterostilbene selectively killed breast cancer stem cells.Mar 10, 2015

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

An ethanolic extract of T. camphoratus treatment further enhanced the tumor suppression efficiency of cisplatin and doxorubicin.Dec 31, 2014

Calebin A potentiates the effect of 5-FU and TNF-β against human colorectal cancer cells.Mar 30, 2020

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Epigenetic upregulation of metallothionein 2A by diallyl trisulfide enhances chemosensitivity of human gastric cancer cells to docetaxel.Jan 21, 2016

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells.Nov 03, 2016

Huaier may be a potential drug for the treatment of cancers caused by aberrant mTOR signaling.Mar 31, 2016

Melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human liver cancer cells.Feb 07, 2017

Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.Mar 30, 2016

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Piperine enhanced mitomycin-C therapy in human cervical cancer cells.Nov 19, 2017

Pterostilbene might be used to modulate two anticancer compounds in well-defined sets of GBM patients.Nov 07, 2016

Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.Dec 31, 2015

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.Oct 31, 2016

Thymoquinone intensified temozolomide-induced apoptosis in U87MG cells.Apr 20, 2017

Ursolic acid could affect the proliferation and apoptosis of human ovarian cancer stem-like cells and it is a potent anti-ovarian cancer agent.Oct 31, 2015

Ursolic acid enhances the sensitivity of MCF-7 and MDA-MB-231 cells to epirubicin.May 24, 2022

Wogonin could increase doxorubicin sensitivity in human breast cancer cells.Dec 31, 2014

3,3'-diindolylmethane enhances fluorouracil sensitivity via inhibition of pyrimidine metabolism in colorectal cancer.Apr 29, 2022

Artesunate Sensitizes human hepatocellular carcinoma to sorafenib.Sep 20, 2023

Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.Dec 30, 2023

Baicalein enhances cisplatin sensitivity in cervical cancer cells by promoting cuproptosis through the Akt pathway.Sep 30, 2024

Chrysin induces autophagy-dependent ferroptosis to increase chemosensitivity to gemcitabine by targeting CBR1 in pancreatic cancer cells.Jan 10, 2021

Curcumol increases the sensitivity of colon cancer to 5-FU.Apr 30, 2021

FBP1 induced by β-elemene enhances the sensitivity of gefitinib in lung cancer.Jan 31, 2023

Fucoidan enhances the chemotherapeutic sensitivity of capecitabine in colon cancer Sep 24, 2022

Ganoderma lucidum enhances carboplatin chemotherapy effect by inhibiting the DNA damage response pathway and stemness.Dec 31, 2021

Ginsenoside Rg3 overcomes tamoxifen resistance through inhibiting glycolysis in breast cancer cells.Jan 14, 2024

Interaction of quercetin and 5-fluorouracil: cellular and pharmacokinetic study.Mar 12, 2023

Isorhamnetin induces cell cycle arrest and apoptosis in doxorubicin-resistant breast cancer.May 31, 2023

Lipid-based nanoparticle formulation of diallyl trisulfide chemosensitizes the growth inhibitory activity of doxorubicin in colorectal cancer.Mar 27, 2022

Low concentration of thymoquinone enhances the inhibitory effects of 5-FU on cell growth in colorectal cancer cell line.Dec 31, 2021

Molecular mechanism of ion channel protein TMEM16A regulated by natural product of narirutin for lung cancer adjuvant treatment.Dec 30, 2022

Oxidative lipid damage by naringenin selectively sensitizes chronic myeloid leukemia cell lines.Sep 02, 2024

Paclitaxel-loaded ginsenoside Rg3 liposomes for drug-resistant cancer therapy.Sep 23, 2022

Piperine improves the sensitivity of osteosarcoma cells to doxorubicin.Mar 08, 2023

Puerarin inhibits EMT induced by oxaliplatin via targeting carbonic anhydrase XII.Dec 31, 2021

Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma.Aug 24, 2022

This reports on the synergistic effects of vitamin C with sorafenib against liver cancers. May 31, 2016

Ursolic acid restores sensitivity to gemcitabine.Jan 14, 2021

Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway.Dec 31, 2019

"Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia."Jun 30, 2012

10-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models.Aug 05, 2020

20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.Dec 31, 2018

6-Gingerol is a potent inducer of p53 reactivation in HPV positive cervical cancer cells through proteasome inhibition.Nov 24, 2015

A combination therapy using silibinin and doxorubicin may show a better therapeutic efficacy in patients with HCC.Jun 30, 2016

A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo.Sep 09, 2020

A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines. Mar 01, 2004

Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.Dec 31, 2020

Adjunctive probiotic Lactobacillus rhamnosus Probio-M9 administration enhances the effect of anti-PD-1 antitumor therapy.Dec 31, 2020

Adjuvant mistletoe therapy should be considered as an auspicious treatment option for glioma patients.Dec 31, 2017

Alleviation of doxorubicin adverse effects via loading into various drug-delivery systems: a comparative study.Apr 18, 2024

An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer.Jun 04, 2017

Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisplatin.Apr 30, 2014

Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice.Dec 31, 2015

Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells.Dec 31, 2018

Anti-tumor effect of Wasabi component, 6-(methylsulfinyl) hexyl isothiocyanate, against endometrial carcinoma cells.Jan 22, 2023

Antineoplaston A10 works synergistically with conventional chemotherapy in human liver cancer transplanted to animals.May 01, 1992

Antitumor effect of epigallocatechin gallate and vincristine in mice with L5178Y lymphoma.Nov 01, 2023

Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.Feb 28, 2019

Artesunate alleviates 5-fluorouracil-induced intestinal damage.Jul 26, 2023

Artesunate promotes sensitivity to sorafenib in hepatocellular carcinoma.Oct 28, 2019

Ascorbate supplementation might help reduce the severe side effects that arise from BETi therapy by reducing the dosage necessary for treatment.Nov 26, 2017

Ascorbic acid chemosensitizes colorectal cancer cells and synergistically inhibits tumor growth.Dec 31, 2017

Chemosensitizer

View the Evidence:
1254 Abstracts with Chemosensitizer Research