Cholinesterase Inhibitors

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25 Substances Researched for Cholinesterase Inhibitors
NameACCKFocus
Huperzine45Locked
Bacopa12Locked
Beet12Locked
Berberine12Locked
Carvacrol12Locked
Curcumin12Locked
Gotu Kola12Locked
Pomegranate12Locked
Thymol12Locked
Vitamin C12Locked
Zataria multiflora12Locked
Coptis chinensis11Locked
Devils Claw11Locked
Ginkgo biloba11Locked
Ginseng11Locked
Green Tea11Locked
Honeysuckle11Locked
Lemon Balm11Locked
Lotus 11Locked
Moringa oleifera11Locked
Onion11Locked
Persimmon 11Locked
Resveratrol11Locked
Sage11Locked
Zerumbone11Locked

View the Evidence:
25 Abstracts with Cholinesterase Inhibitors Research

[+]

Beetroot supplemented diet exhibit anti-amnesic effect.Oct 14, 2020

Pubmed Data : Nutr Neurosci. 2020 Oct 15:1-15. Epub 2020 Oct 15. PMID: 33054666
Article Published Date : Oct 14, 2020
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Amnesia
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Brahmi promises to be a novel agent in Alzheimer's disease.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Neurosci. 2017 May ;24(2):111-122. Epub 2017 May 12. PMID: 28588366
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Alzheimer's Disease
Pharmacological Actions : Cholinesterase Inhibitors, Lipoxygenase Inhibitors, Neuroprotective Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.May 31, 2012

Pubmed Data : Behav Pharmacol. 2012 Jun ;23(3):241-9. PMID: 22470103
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cholinesterase Inhibitors
[+]

Comparison of three different extracts of Centella asiatica for anti-amnesic, antioxidant and anticholinergic activities.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1344-1352. Epub 2018 Jun 27. PMID: 30021372
Article Published Date : Aug 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gotu Kola
Diseases : Amnesia
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Curcumin's neuroprotective properties may be due to its anticholinesterase, antioxidant activity and brain insulin receptor modulating activities.Mar 01, 2010

Pubmed Data : Pharmacol Res. 2010 Mar;61(3):247-52. Epub 2009 Dec 21. PMID: 20026275
Article Published Date : Mar 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Dementia, Memory Disorders
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Insulin Receptor Modulator
[+]

Huperzine induces alteration in oxidative balance and antioxidants.Dec 31, 2010

Pubmed Data : Neuro Endocrinol Lett. 2011 ;32 Suppl 1:95-100. PMID: 22167216
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease, Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

These findings highlight the neuroprotective effects of pomegranate extracts.Jun 26, 2017

Pubmed Data : BMC Complement Altern Med. 2017 Jun 27 ;17(1):339. Epub 2017 Jun 27. PMID: 28655305
Article Published Date : Jun 26, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : High Fructose Diet, Obesity
Pharmacological Actions : Cholinesterase Inhibitors, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Treatment with berberine prevents the changes in oxidative stress and ChE activity, and consequently memory impairment in ethanol treated rats.Jul 05, 2015

Pubmed Data : Pharmacol Biochem Behav. 2015 Jul 6 ;136:13-20. Epub 2015 Jul 6. PMID: 26159088
Article Published Date : Jul 05, 2015
Study Type : Animal Study
Additional Links
Substances : Berberine, Vitamin C
Diseases : Alcohol Toxicity , Cognitive Decline/Dysfunction, Memory Disorders: Drug-Induced, Oxidative Stress
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Zataria multiflora has anti-amnesic effect and might improve memory deficit through anticholinesterase activity.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):587-596. PMID: 31763217
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Zataria multiflora
Diseases : Amnesia: Drug-Induced
Pharmacological Actions : Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Allium cepa fraction attenuates STZ-induced dementia.Mar 10, 2020

Pubmed Data : J Basic Clin Physiol Pharmacol. 2020 Mar 11 ;31(3). Epub 2020 Mar 11. PMID: 32160161
Article Published Date : Mar 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Onion
Diseases : Dementia, Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

An ethyl acetate soluble fraction of the roots of Harpagophytum procumbens was found to inhibit AChE activity.Dec 31, 2013

Pubmed Data : Arch Pharm Res. 2014 ;37(9):1124-9. Epub 2013 Dec 28. PMID: 24374905
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Devils Claw
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
Additional Keywords : Plant Extracts
[+]

Cholinesterase inhibitory alkaloids from the rhizomes of Coptis chinensis.Feb 22, 2018

Pubmed Data : Bioorg Chem. 2018 Feb 23 ;77:625-632. Epub 2018 Feb 23. PMID: 29502023
Article Published Date : Feb 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Coptis chinensis
Diseases : Alzheimer's Disease
Pharmacological Actions : Cholinesterase Inhibitors
[+]

Discovery of potent and selective dual cholinesterases and β-secretase inhibitors in pomegranate as a treatment for Alzheimer's disease.Sep 09, 2022

Pubmed Data : Bioorg Chem. 2022 Sep 10 ;129:106137. Epub 2022 Sep 10. PMID: 36108590
Article Published Date : Sep 09, 2022
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Huperzine A has greater efficacy than the drugs donepezil and rivastigmine in raising brain levels of acetylcholine and dopamine in freely-moving rats.Sep 01, 2006

Pubmed Data : Acta Pharmacol Sin. 2006 Sep;27(9):1127-36. PMID: 16923332
Article Published Date : Sep 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease
Pharmacological Actions : Cholinesterase Inhibitors, Dopaminergic, Neuroprotective Agents
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Huperzine A has neuroprotective effects beyond the ability to inhibit acetylcholinesterase activity. Feb 01, 2008

Pubmed Data : Cell Mol Neurobiol. 2008 Feb;28(2):173-83. Epub 2007 Jul 27. PMID: 17657601
Article Published Date : Feb 01, 2008
Study Type : Review
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Huperzine has significant therapeutic activity in neurological conditions such as Alzheimers.Jan 01, 2005

Pubmed Data : Neurosignals. 2005;14(1-2):71-82. PMID: 15956816
Article Published Date : Jan 01, 2005
Study Type : Review
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease
Pharmacological Actions : Cholinesterase Inhibitors
[+]

M. oleifera has in vitro anti-cholinesterase and antioxidant activities.Jul 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2018 Jul 5 ;5(3). Epub 2018 Jul 5. PMID: 29976887
Article Published Date : Jul 04, 2018
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors
[+]

N. nucifera possesses potent cholinesterases and BACE1-inhibitory activities.May 31, 2015

Pubmed Data : Arch Pharm Res. 2015 Jun ;38(6):1178-87. Epub 2014 Oct 11. PMID: 25300425
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors
Additional Keywords : Plant Extracts
[+]

N. sativa is a good candidate for seeking the new anticholinesterase agent and could be considered as a good supplement for the health of the elderly.Aug 07, 2019

Pubmed Data : Curr Aging Sci. 2019 Aug 8. Epub 2019 Aug 8. PMID: 31418667
Article Published Date : Aug 07, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Neurodegenerative Diseases
Pharmacological Actions : Cholinesterase Inhibitors, Neuroprotective Agents
[+]

New cholinesterase inhibitory constituents from Lonicera quinquelocularis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(4):e94952. Epub 2014 Apr 14. PMID: 24733024
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Honeysuckle
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
[+]

Persimmon an active source of natural antioxidants and acetylcholinesterase inhibitors. Jul 07, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Jul 8 ;21(7). Epub 2016 Jul 8. PMID: 27399664
Article Published Date : Jul 07, 2016
Study Type : In Vitro Study
Additional Links
Substances : Persimmon
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Cholinesterase Inhibitors, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Potential benefits of phytochemicals against Alzheimer's disease.Jan 31, 2017

Pubmed Data : Proc Nutr Soc. 2017 Feb 1:1-7. Epub 2017 Feb 1. PMID: 28143625
Article Published Date : Jan 31, 2017
Study Type : Review
Additional Links
Substances : Ginkgo biloba, Ginseng, Lemon Balm, Resveratrol, Sage
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Profile of phenolic compounds of Prunus armeniaca L. leaf extract.Nov 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Nov 24 ;10(12). Epub 2021 Nov 24. PMID: 34942972
Article Published Date : Nov 23, 2021
Study Type : In Vitro Study
Additional Links
Substances : Apricot
Diseases : Hyperglycemia, Oxidative Stress
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Antioxidants, Cholinesterase Inhibitors, Hypoglycemic Agents
[+]

Tea polyphenols inhibit AChE as well as BChE and enhance the cholinergic neurotransmission by prolonging the time.Mar 20, 2016

Pubmed Data : CNS Neurol Disord Drug Targets. 2016 Mar 21. Epub 2016 Mar 21. PMID: 26996169
Article Published Date : Mar 20, 2016
Study Type : In Vitro Study
Additional Links
Substances : Green Tea
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
[+]

Zerumbone was clearly identified as a unique dual acetylcholinesterase and butyrylcholinesterase inhibitor.Apr 24, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 25 ;12(5). Epub 2020 Apr 25. PMID: 32344943
Article Published Date : Apr 24, 2020
Study Type : In Vitro Study
Additional Links
Substances : Zerumbone
Diseases : Alzheimer's Disease
Pharmacological Actions : Cholinesterase Inhibitors, Neuroprotective Agents
Additional Keywords : Risk Reduction

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