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Cyclooxygenase 2 Inhibitors
Views 1899
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419 Substances Researched for Cyclooxygenase 2 Inhibitors
Name
AC
CK
Focus
Curcumin
76
120
Flavonoids
30
60
Ginsenosides
21
34
Resveratrol
20
31
Frankincense
8
29
Omega-3 Fatty Acids
8
28
Sulforaphane
15
23
Cannabis
7
22
Melatonin
11
22
Polyphenols
14
22
Oleuropein
6
21
Vitamin C
7
20
Phloretin
5
19
Berberine
11
18
Spirulina
5
18
Fisetin
11
16
Thymoquinone
9
16
Turmeric
7
16
Rose
10
15
Cannabinoids
4
13
DHA (Docosahexaenoic Acid)
4
13
Ginseng (Korean)
10
13
Apples
2
12
Astaxanthin
7
12
Quercetin
9
12
Rosmarinic acid
7
12
Sesamin
2
12
Anthocyanins
7
11
Banana
2
11
EPA (Eicosapentaenoic Acid)
2
11
Fucoxanthin
6
11
Grape
6
11
Pomegranate
7
11
Strawberry
2
11
Diosmin
6
10
Eicosapentaenoic acid (EPA)
1
10
Gingerol
6
10
MSM (Methylsulfonylmethane)
1
10
Myricetin
8
10
Tocotrienols
1
10
Ginger
5
9
Hesperidin
5
9
Paeoniflorin
6
9
Adlay
6
8
Chrysin
5
8
Dandelion
6
8
Dogwood
5
8
Geraniol
4
8
Ginkgo biloba
5
8
Lignans
4
8
Lotus
6
8
Nobiletin
6
8
Seaweed: Brown
3
8
Stilbenes
5
8
Tanshinone IIA
7
8
Wogonin
6
8
Bee Venom
5
7
Citrus naringin
5
7
Ellagic Acid
5
7
Fermented Foods and Beverages
6
7
Formononetin
5
7
Grape Seed Extract
4
7
Japanese cypress
4
7
Lycopene
5
7
Mangiferin
5
7
Mulberry
6
7
Noni
4
7
Oleocanthal
3
7
Oligonol
4
7
Patchouli
4
7
Pterostilbene
5
7
Reishi Mushroom
5
7
Zerumbone
4
7
Antrodia camphorata
4
6
Beta-Caryophyllene
4
6
Black Tea
4
6
Cannabidiol
4
6
Honokiol
4
6
Indole-3-Carbinol
3
6
Isoliquiritigenin
4
6
Licorice
3
6
Olive
5
6
Puerarin
4
6
Punicalagin
4
6
Rutin
3
6
Shikonin
3
6
Tetrahydrocurcumin
3
6
Walnut
4
6
Alpha-Lipoic Acid
3
5
Apigenin
3
5
Artesunate
3
5
Carnosol
3
5
Carvacrol
3
5
Catechin
4
5
Citrus Peel
3
5
EGCG (Epigallocatechin gallate)
5
5
Genipin
3
5
Gotu Kola
3
5
Hydroxytyrosol
3
5
Justicia gendarussa
3
5
Luteolin
5
5
Moringa oleifera
3
5
Naringenin
3
5
Nettle
3
5
Palmitoylethanolamide
3
5
Perilla
3
5
Probiotics
3
5
Raspberry
3
5
Red Clover
4
5
Sesamol
3
5
Tangeretin
4
5
Vitex negundo
3
5
Water: Deuterium Depleted
3
5
Apple Polyphenols
2
4
Arginine
2
4
Astragaloside
2
4
Blueberry
3
4
Bromelain
4
4
Brown Rice
2
4
Chaga Mushroom (Inonotus obliquus)
3
4
Cordyceps sinensis
2
4
Crocin
3
4
D-Limonene
2
4
Daidzein
3
4
Delta-tetrahydrocannabinol (THC)
3
4
Ferulic acid
3
4
Flaxseed
2
4
Fucoidan
3
4
Garlic
3
4
Honeysuckle
3
4
Lactobacillus fermentum
2
4
Lactobacillus plantarum
3
4
Lion's Mane (Hericium Erinaceus)
2
4
Lychee
2
4
Magnolol
2
4
Medicinal Mushrooms
3
4
Medium Chain Triglycerides
2
4
Nexrutine (Phellodendrom)
3
4
Nigella sativa (aka Black Seed)
4
4
P-Coumaric Acid
3
4
Paeonol
3
4
Palm Oil
2
4
Peony
3
4
Piceatannol
3
4
Piperlongumine
3
4
Rice Bran
2
4
Royal Jelly
2
4
Saffron
3
4
Saturated fatty acids
2
4
Sea buckthorn
2
4
Sweet Potato: Purple
2
4
Toona sinensis
3
4
Ursolic Acid
4
4
Vitamin D
2
4
Vitamin E
2
4
White Tea
2
4
18β-Glycyrrhetinic Acid
2
3
Aduki bean
2
3
Arctigenin
2
3
Asiatic Acid
2
3
Avocado
2
3
Bee Propolis
2
3
Bitter Melon
3
3
Bitter Orange
3
3
Caffeic acid phenethyl ester
2
3
Chamomile
2
3
Chinese Skullcap
2
3
Crocetin
2
3
Diosgenin
2
3
Eriodictyol
2
3
Gastrodin
2
3
Genistein
3
3
Ginseng (American)
2
3
Honey
2
3
Hops
2
3
Isoflavones
2
3
Isothiocyanates
2
3
Kimchi
3
3
Lupeol
2
3
Maitake Mushroom
2
3
Olive leaf extract
2
3
Phellinus Linteus
2
3
Polyunsaturated Fatty Acids (PUFAs)
2
3
Red Sage
2
3
Rosemary
2
3
Safflower
2
3
Silibinin
2
3
Tocotrienol: Gamma
2
3
5-HTP (5-Hydroxytryptophan)
1
2
6-Shogaol
1
2
ALA (Alpha-Linolenic Acid)
1
2
Acai
1
2
African Basil
1
2
Agaricus Blazei
1
2
Alpha Linolenic Acid
1
2
Angelica
2
2
Apocynin
1
2
Apple
1
2
Artemisia asiatica
1
2
Artemisinin
2
2
Asparagus
2
2
Bai Zhu
1
2
Barley
1
2
Benzyl isothiocyanate
1
2
Bergamot
1
2
Betulinic acid
2
2
Black Currant
1
2
Boswellia
1
2
Brazil nut
1
2
Burdock
1
2
Butterbur
2
2
Camel Milk
1
2
Cardamonin
1
2
Carrot
1
2
Chickpea
2
2
Chlorogenic Acid
1
2
Chokeberry
1
2
Chrysanthemum Indicum
2
2
Chrysanthemum Morifolium
2
2
Citrus Oils
1
2
Cocoa
1
2
Coptis chinensis
1
2
Cordyceps Militaris
1
2
Corn: Purple
1
2
Cranberry
1
2
Curry Tree
1
2
Cyanidin 3-glucoside
1
2
Damnacanthal
1
2
Delphinidin
1
2
Demethoxycurcumin
1
2
Emodin
1
2
Evening Primrose Oil
1
2
Gallic Acid
1
2
Garcinia indica
1
2
Gardenia
1
2
Ginseng
1
2
Ginseng (Siberian)
1
2
Gold (nanoparticles)
1
2
Graviola
1
2
Green Tea
1
2
Guggul
2
2
Hazelnut
2
2
Hemp Seed
1
2
Horseradish
2
2
Hu Zhang (Polygonum cuspidatum)
1
2
Hydrogen Water
1
2
Isoquercitrin
1
2
Kaempferia parviflora
1
2
Kaempferol
1
2
Krill
1
2
L-Carnitine
1
2
Lactobacillus paracasei
1
2
Lactobacillus rhamnosus
1
2
Lavender
1
2
Ligustrazine
1
2
Loquat
1
2
Magnolia
1
2
Manuka Honey
1
2
Mint
1
2
Myo-inositol
1
2
Noni leaf extract
1
2
Nutmeg
1
2
Oak
1
2
Orange
1
2
Panax Ginseng
1
2
Papaya
1
2
Paprika
1
2
Pau D'Arco
1
2
Pelargonium sidoides
1
2
Peppermint
1
2
Pine Needle
1
2
Pineapple
1
2
Plantago asiatica
1
2
Polypodium leucotomos
1
2
Poria cocos
2
2
Potato
1
2
Psychedelics:All
2
2
Raspberry ketone
1
2
Red Wine
1
2
Rosemaric Acid
1
2
Ruta Graveolens
1
2
Schisandra
1
2
Selenium
1
2
Shiitake Mushroom
1
2
Sour Cherry
1
2
Taurine
1
2
Tea
1
2
Theaflavins
2
2
Thistle
1
2
Thuja
1
2
Thymol
1
2
Tongkat Ali
1
2
Turmeric: Fermented
1
2
Urolithin A
1
2
Vanillin
2
2
Verbascoside
2
2
Vinegar
1
2
Watermelon
1
2
Wheat Germ
2
2
Xanthohumol
1
2
Yam
1
2
Yeast
1
2
Yoghurt
1
2
Zeaxanthin
1
2
acetyl-11-keto-beta-boswellic acid
1
2
Achillea fragrantissima
1
1
Almond
1
1
Amla Fruit
1
1
Amygdalin (laetrile)
1
1
Apple Pectin
1
1
Ashwagandha
1
1
Avacado
1
1
Avenanthramides
1
1
Baicalein
1
1
Bamboo
1
1
Beet
1
1
Beta-glucan
1
1
Bifidobacterium Breve
1
1
Biochanin A
1
1
Black Pepper
1
1
Black Raspberry
1
1
Capsaicin
1
1
Carnosic Acid
1
1
Celastrol
1
1
Celery
1
1
Celery seed
1
1
Cherry: All Varieties
1
1
Chlorella (Algae)
1
1
Citric Acid
1
1
Coenzyme Q10
1
1
Coumestrol
1
1
Cucurbitacin B
1
1
Cumin
1
1
Cyanidin
1
1
Deguelin
1
1
Echinacea
1
1
Eugenol
1
1
False Black Pepper
1
1
Feverfew
1
1
Fish Oil
1
1
Fruit: All
1
1
Gleditsia sinensis
1
1
Glycyrrhizin
1
1
Green Coffee Bean
1
1
Guava
1
1
Homeopathic Medicine: All
1
1
Huperzine
1
1
Hyaluronic Acid
1
1
Jujube
1
1
Kahweol
1
1
Kava Kava
1
1
Lactobacillus reuteri
1
1
Lactobacillus rhamnosus GG
1
1
Long Pepper
1
1
Loquat Leaves
1
1
Lutein
1
1
Macadamia
1
1
Maqui
1
1
Mastic gum
1
1
Modified Citrus Pectin
1
1
Mushrooms: All
1
1
Mussel: Green-lipped (Perna canaliculus)
1
1
Nuts
1
1
Oats
1
1
Olive Oil
1
1
Onion
1
1
Orange: Mandarin
1
1
Oranges
1
1
Oridonin
1
1
Orthosiphon
1
1
Panax Notoginseng
1
1
Parthenolide
1
1
Passion Flower
1
1
Pea
1
1
Persimmon
1
1
Phenethyl isothiocyanate
1
1
Phyllanthus amarus
1
1
Pine Cone
1
1
Piperine
1
1
Pistachio nut
1
1
Plantago
1
1
Pomegranate Peel
1
1
Prickly Pear Cactus
1
1
Prunella vulgaris
1
1
Purple Carrots
1
1
Quince
1
1
Radish
1
1
Raisins
1
1
Rice: Black
1
1
Rooibos
1
1
Rose Hips
1
1
Sarsaparilla
1
1
Saw Palmetto
1
1
Sesame Seeds
1
1
Shallot
1
1
Silver (nanoparticles)
1
1
Skullcap: Chinese
1
1
Soy
1
1
Spikenard
1
1
Syrian rue
1
1
Tabebuia
1
1
Tamarind
1
1
Tart Cherry
1
1
Terminalia chebula
1
1
Truffles
1
1
Turmerones
1
1
Tyrosol
1
1
Unsaponifiables
1
1
Vegetables: All
1
1
Vitamin E: alpha tocopherol
1
1
Wasabi
2
1
White Button Mushroom
1
1
White Clover
1
1
White Mulberry
1
1
Wild basil
1
1
Wormwood
1
1
Yellow Sweet Clover (Melilotus officinalis)
1
1
Zinc
1
1
beta-Carotene
1
1
Research Articles
926
Cumulative Knowledge Score
1498
Overall Research Rating
EXCELLENT
View the Evidence:
1204 Abstracts with Cyclooxygenase 2 Inhibitors Research
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[+]
Piperine suppresses inflammatory fibroblast-like synoviocytes derived from rheumatoid arthritis patients.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Cell Immunol. 2023 ;391-392:104752. Epub 2023 Jul 22. PMID:
37536000
Article Published Date
: Dec 31, 2022
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Piperine
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.
Jan 01, 2005
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5. PMID:
15668484
Article Published Date
: Jan 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Antineoplastic Agents
[+]
A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.
Oct 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID:
24002213
Article Published Date
: Oct 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Frankincense
,
Turmeric
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
,
Superiority of Natural Substances versus Drugs
Problem Substances
:
Celecoxib
,
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Carbohydrate ingestion from bananas had positive influence in attenuating metabolic perturbation and inflammation following 75-km cycling.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2018 ;13(3):e0194843. Epub 2018 Mar 22. PMID:
29566095
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Banana
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Consumption of dried apple peel powder was associated with improved joint function and improved serum antioxidant protection status.
Oct 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2014 Nov ;17(11):1204-13. Epub 2014 Oct 1. PMID:
25271471
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Apples
Diseases
:
Joint Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antinoceceptive
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Lipoxygenase Inhibitors
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2012 Jan ;5(1):41-50. Epub 2011 Dec 1. PMID:
22135048
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
,
Risk Reduction
[+]
Electroacupuncture may prevent ischemia-reperfusion-induced endothelial dysfunction via a COX-2 dependent mechanism.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(6):e0178838. Epub 2017 Jun 7. PMID:
28591155
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Endothelial Dysfunction
,
Ischemia
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
[+]
Electroacupuncture treatment alleviates central post-stroke pain.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Plast. 2016 ;2016:1437148. Epub 2016 Aug 27. PMID:
27774321
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Stroke: Attenuation/Recovery
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Analgesics
,
Cyclooxygenase 2 Inhibitors
[+]
EPA supplementation significantly reduces Cox-2 enzyme expression in Barrett's esophagus.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2008 Apr;87(4):949-56. PMID:
18400718
Article Published Date
: Apr 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Barrett Esophagus
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
[+]
Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2016 Mar ;29(1):140-6. Epub 2015 Dec 18. PMID:
26684635
Article Published Date
: Feb 29, 2016
Study Type
: Human Study
Additional Links
Substances
:
Frankincense
,
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Omega-3 fatty acids cause a reduction in the mRNA levels for various proteins known to be important in the pathology of osteoarthritis.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Osteoarthritis Cartilage. 2009 Jul;17(7):896-905. Epub 2009 Jan 13. PMID:
19217322
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
Eicosapentaenoic acid (EPA)
,
Omega-3 Fatty Acids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Phloretin inhibits the growth of P. acnes, P. granulosum, and S. epidermidis.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Cosmet Sci. 2016 Feb ;38(1):85-92. Epub 2015 Aug 30. PMID:
26212527
Article Published Date
: Jan 31, 2016
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Phloretin
Diseases
:
Acne
Pharmacological Actions
:
Anti-Bacterial Agents
,
Antimicrobial
,
Cyclooxygenase 2 Inhibitors
,
Prostaglandin PGE2 downregulation
[+]
Pycnogenol may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2012 Feb 15 ;52(4):765-74. Epub 2011 Dec 13. PMID:
22198264
Article Published Date
: Feb 14, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gout
,
Hyperuricemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators
Jan 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Psychoneuroendocrinology. 2014 Feb ;40:96-107. Epub 2013 Nov 15. PMID:
24485481
Article Published Date
: Jan 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Meditation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Histone deacetylase inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Sesamin can relieve clinical symptoms and pathological changes that caused by inflammatory impairment in patients with rheumatoid arthritis.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Sep ;33(9):2421-2428. Epub 2019 Jul 15. PMID:
31309643
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Sesamin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Spirulina has favorable effects on lipid profiles, immune variables and antioxidant capacity in healthy individuals.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Ann Nutr Metab. 2008;52(4):322-8. Epub 2008 Aug 19. PMID:
18714150
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Spirulina
Diseases
:
High Cholesterol
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-2 upregulation
,
Interleukin-6 Downregulation
[+]
The anti-inflammatory activity of Cannabis extracts on colon epithelial cells derives from a fraction of the extract that contains THCA.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2017 ;2(1):167-182. Epub 2017 Jul 1. PMID:
29082314
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
The data support the strategy of flavonoid supplementation to mitigate post-exercise oxidative stress in endurance athletes.
Nov 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Sport Nutr Exerc Metab. 2019 Nov 21:1-8. Epub 2019 Nov 21. PMID:
31754080
Article Published Date
: Nov 20, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Athletic Performance: Recovery
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
MicroRNA modulator
,
Nrf2 activation
[+]
These findings indicate that combination therapy of ω-3 fatty acids and nano-curcumin can be considered as a promising new approach in migraine prevention.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2019 ;19(6):874-884. PMID:
30760195
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Omega-3 Fatty Acids
Diseases
:
Headache: Migraine
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
Prophylactic Agents
[+]
These new data support a potential role of oleuropein in the treatment of ulcerative colitis.
Apr 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Apr 15 ;9(4). Epub 2017 Apr 15. PMID:
28420140
Article Published Date
: Apr 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-17 downregulation
[+]
Tocotrienols attenuate UV-induced inflammaging.
Jun 01, 2018
Click here to read the entire abstract
Pubmed Data
: J Cosmet Dermatol. 2018 Jun ;17(3):555-565. Epub 2017 Sep 26. PMID:
28952200
Article Published Date
: Jun 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Tocotrienols
Diseases
:
Oxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
[+]
Vitamin C attenuates aspirin-induced gastric damage.
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2009 May;29(5):382-4. PMID:
17218764
Article Published Date
: May 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Aspirin-Induced Toxicity
,
NSAID-induced toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
[+]
Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2011 Oct ;49(10):2580-5. Epub 2011 Jul 13. PMID:
21771629
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Berberine alleviates myocardial ischemia-reperfusion injury.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):652-663. PMID:
35311466
Article Published Date
: Nov 30, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Cyclooxygenase 2 Inhibitors
[+]
Betulinic acid exerts anti-inflammatory activity in human periodontal ligament cells stimulated with lipopolysaccharide or high glucose.
May 08, 2022
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2022 May 9. Epub 2022 May 9. PMID:
35538811
Article Published Date
: May 08, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Betulinic acid
Diseases
:
Diabetic Complications
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Cannabidiolic acid an active component in the cannabis plant offers potential therapeutic modality in the abrogation of cancer cell migration.
Nov 14, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Lett. 2012 Nov 15 ;214(3):314-9. Epub 2012 Sep 8. PMID:
22963825
Article Published Date
: Nov 14, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabis
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Ginsenoside Rg1 can inhibit inflammatory responses in human chondrocytes in vitro and reduce articular cartilage damage in vivo.
Mar 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 10 ;9(3). Epub 2017 Mar 10. PMID:
28287423
Article Published Date
: Mar 09, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Chondroprotective
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Marine alga Ecklonia cava extract and dieckol attenuate prostaglandin E2 production in HaCaT keratinocytes exposed to airborne particulate matter.
Jun 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2019 Jun 21 ;8(6). Epub 2019 Jun 21. PMID:
31234405
Article Published Date
: Jun 20, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Seaweed: Brown
Diseases
:
Air Pollution Linked Toxicity
,
Lung Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Melatonin as a novel selective ATF-6 inhibitor can sensitize human hepatoma cells to ER stress inducing apoptosis.
Feb 13, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2017 Feb 14 ;23(6):986-998. PMID:
28246472
Article Published Date
: Feb 13, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
Cyclooxygenase 2 Inhibitors
[+]
Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID:
22348531
Article Published Date
: Aug 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(6):2414-2426. Epub 2018 Sep 27. PMID:
30261513
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleocanthal
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oleuropein might provide a basis for developing a new dietary strategy for the prevention and management of rheumatoid arthritis.
Apr 19, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Apr 20. Epub 2017 Apr 20. PMID:
28426090
Article Published Date
: Apr 19, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleuropein
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Jun ;6(6):1960-7. PMID:
25996641
Article Published Date
: May 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Phloretin
Diseases
:
Experimental Lung Inflammation
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Prostaglandin PGE2 downregulation
[+]
Resveratrol functions as a suppressor of particulate matter induced inflammatory signalling pathways.
May 07, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Biochem Cell Biol. 2017 May 8 ;88:113-123. Epub 2017 May 8. PMID:
28495310
Article Published Date
: May 07, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Air Pollution Linked Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID:
30041241
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-cancer
,
Anti-metastatic
,
Anti-Proliferative
,
Cyclooxygenase 2 Inhibitors
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Anti-inflammatory effect of fucoidan isolated from fermented Sargassum fusiforme in in vitro and in vivo models.
Oct 04, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2022 Oct 5. Epub 2022 Oct 5. PMID:
36208806
Article Published Date
: Oct 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 alpha downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anticancer investigation of fullerene C60 on DMBA induced breast cancer.
Feb 14, 2022
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2022 Feb 15 ;291:120281. Epub 2022 Jan 1. PMID:
34982963
Article Published Date
: Feb 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Carbon 60
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antineoplastic Agents
,
Antioxidants
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 alpha downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer's disease.
Jan 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Feb ;9(2):e13411. Epub 2023 Feb 3. PMID:
36820018
Article Published Date
: Jan 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Farrerol ameliorates TNBS-induced colonic inflammation.
Jul 12, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 13 ;19(7). Epub 2018 Jul 13. PMID:
30011811
Article Published Date
: Jul 12, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Ginkgolide A ameliorates lipopolysaccharide-induced inflammatory responses.
Apr 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Apr 10 ;18(4). Epub 2017 Apr 10. PMID:
28394269
Article Published Date
: Apr 09, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
In vitro and in vivo assessment of the anti-inflammatory activity of olive leaf extract in rats.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2023 Jun ;31(3):1529-1538. Epub 2023 Apr 8. PMID:
37029328
Article Published Date
: May 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Olive leaf extract
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Macrophage-targeted berberine-loaded β-glucan nanoparticles enhance the treatment of ulcerative colitis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2022 ;17:5303-5314. Epub 2022 Nov 14. PMID:
36406639
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
,
Beta-glucan
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation.
Sep 12, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2023 Sep 13 ;167:115501. Epub 2023 Sep 13. PMID:
37713995
Article Published Date
: Sep 12, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Salvia miltiorrhiza
,
Tanshinone IIA
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19.
Oct 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytomed Plus. 2021 Nov ;1(4):100058. Epub 2021 Mar 18. PMID:
35403084
Article Published Date
: Oct 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Green Tea
,
Guava
,
Rose
Diseases
:
Coronavirus Infection
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0123478. Epub 2015 May 8. PMID:
25954974
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Effect of oleuropein on oxidative stress, inflammation and apoptosis induced by ischemia-reperfusion injury in rat kidney.
Aug 14, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Aug 15 ;255:117833. Epub 2020 May 22. PMID:
32450167
Article Published Date
: Aug 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Inflammation
,
Ischemia
,
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
[+]
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study
Mar 25, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Mar 26 ;11(3):2654-2666. PMID:
32159191
Article Published Date
: Mar 25, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Nrf2 activation
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Therapeutic effect of melittin on a rat model of chronic prostatitis induced by complete freund's adjuvant.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Jun ;90:921-927. Epub 2017 Apr 22. PMID:
28441718
Article Published Date
: May 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Hyperalgesia
,
Inflammation
,
Prostatitis: Chronic
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."
Feb 15, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID:
21167192
Article Published Date
: Feb 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Tumor Suppressor Protein p53 Upregulation
[+]
18β-Glycyrrhetinic acid significantly attenuated H. pylori-infected gastritis in gerbils.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2016 ;2016:4943793. Epub 2016 Feb 24. PMID:
27006947
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
18β-Glycyrrhetinic Acid
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside may be a promising natural lead compound for treating early phases of colorectal cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:3634915. Epub 2017 Nov 7. PMID:
29238715
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2019 Feb 1 ;448:20-30. Epub 2019 Feb 1. PMID:
30716361
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
[+]
5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID:
27468227
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Gene Expression Regulation
[+]
5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis.
Jan 10, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2018 11 ;27(11):1273-1279. Epub 2018 Oct 9. PMID:
30221419
Article Published Date
: Jan 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
5-HTP (5-Hydroxytryptophan)
Diseases
:
Dermatitis
,
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Gingerol abates benzo[a]pyrene-induced colonic injury.
Apr 17, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2019 Apr 18 ;307:1-7. Epub 2019 Apr 18. PMID:
31004597
Article Published Date
: Apr 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Benzo[a]pyrene-induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Benzo(a)pyrene
[+]
6-gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer.
Jun 04, 2020
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2020 Jun 5 ;142:111483. Epub 2020 Jun 5. PMID:
32512025
Article Published Date
: Jun 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Problem Substances
:
Benzo(a)pyrene
[+]
6-gingerol prevented DSS-induced chronic ulcerative colitis via anti-inflammatory and antioxidative mechanisms.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2018 Jan 1:960327117751235. Epub 2018 Jan 1. PMID:
29350052
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
6-Shogaol reduces progression of experimental endometriosis.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2018 Nov ;22(6):627-636. Epub 2018 Oct 25. PMID:
30402023
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
[+]
A Burdock extract was able to reduce intestinal inflammation in an acute TNBS-induced experimental model of colitis in rats.
Mar 06, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ethnopharmacol. 2013 Mar 7 ;146(1):300-10. Epub 2013 Jan 10. PMID:
23313393
Article Published Date
: Mar 06, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
A combination of ginger and peony root may prevent memory impairment in AD by inhibiting Aβ accumulation and inflammation in the brain.
Nov 29, 2015
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2015 Nov 30. Epub 2015 Nov 30. PMID:
26639976
Article Published Date
: Nov 29, 2015
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginger
,
Peony
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID:
30919084
Article Published Date
: Mar 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Metab. 2017 Dec ;6(12):1563-1573. Epub 2017 Oct 18. PMID:
29107524
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cranberry
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A. paniculata extract can be used for prevention and treatment of cardiovascular disease in obese patients.
Nov 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Nov 4 ;192:170-177. Epub 2016 Jul 9. PMID:
27401291
Article Published Date
: Nov 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Cardiac Hypertrophy
,
High Fat Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Acacetin alleviates inflammation and matrix degradation in nucleus pulposus cells and ameliorates intervertebral disc degeneration.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:4801-4813. Epub 2020 Nov 10. PMID:
33204066
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Degenerative Disk Disease
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Acacetin attenuates neuroinflammation.
Jun 30, 2012
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2012 Jul ;37(7):1560-7. Epub 2012 Mar 24. PMID:
22447574
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
Postaglandin PGE2 downregulation
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Activities of Andrographis paniculata tablet on Cox-2 and prostaglandin expression of placental of Plasmodium berghei infection.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Parasitol. 2021 Jan-Mar;16(1):43-51. PMID:
33786046
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Malaria
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Adlay bran ethanolic extract suppressed 1,2-dimethylhydrazine-indued preneoplastic lesions of the colon.
Jul 13, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Jul 14 ;58(13):7616-23. PMID:
20536243
Article Published Date
: Jul 13, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Adlay
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Adlay
,
Anti-Inflammatory Agents
,
Chemopreventive
,
COLON CANCER
,
Cyclooxygenase 2 Inhibitors
,
Plant Extracts
[+]
Administration of chlorogenic acid alleviates spinal cord injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2018 Jan ;17(1):1340-1346. Epub 2017 Nov 6. PMID:
29115619
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Alleviative effects of pinostrobin against cadmium-induced renal toxicity.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Front Nutr. 2023 ;10:1175008. Epub 2023 May 24. PMID:
37342552
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cadmium
[+]
Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(7):e102975. Epub 2014 Jul 22. PMID:
25051185
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Colitis
,
Inflammation
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Allylmethylsulfide (AMS), a volatile organosulfur derivative from garlic has radioprotective properties.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Jun;12(3):542-51. PMID:
19627202
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Lipid Peroxidation
,
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Radioprotective
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Alpha linolenic fatty acid supplementation had a beneficial effect on tumor cell proliferation and cachexia parameters.
May 25, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 May 26:1-8. Epub 2015 May 26. PMID:
26011096
Article Published Date
: May 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Alpha Linolenic Acid
Diseases
:
Breast Cancer
,
Cachexia
Pharmacological Actions
:
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha lipoic acid has hepatoprotective effects against methotrexate-induced hepatic injury.
Jun 03, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jun 4 ;105:428-433. Epub 2018 Jun 4. PMID:
29879626
Article Published Date
: Jun 03, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Drug-Induced Toxicity: Methotrexate
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction.
Jul 06, 2020
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2020 Jul 7 ;442:152536. Epub 2020 Jul 7. PMID:
32649955
Article Published Date
: Jul 06, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Radiation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Radioprotective
Anti Therapeutic Actions
:
Low Dose Ionizing Radiation
[+]
Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne.
May 09, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 May 10 ;235:460-471. Epub 2019 Feb 13. PMID:
30771518
Article Published Date
: May 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Currant
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Amelioration of experimental autoimmune encephalomyelitis by Ishige okamurae.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anat Cell Biol. 2018 Dec ;51(4):292-298. Epub 2018 Dec 29. PMID:
30637164
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Seaweed: Brown
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ameliorative effects of hempseed against hypercholesterolemia associated cardiovascular changes.
Sep 12, 2019
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2019 Sep 13. Epub 2019 Sep 13. PMID:
31668458
Article Published Date
: Sep 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Hemp Seed
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hypolipidemic
[+]
Ameliorative effects of loganin on arthritis in chondrocytes.
Feb 07, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2021 Feb 8 ;14(2). Epub 2021 Feb 8. PMID:
33567513
Article Published Date
: Feb 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Dogwood
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
American ginseng prevents and treats Ulcerative Colitis.
Sep 18, 2008
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2008 Sep 18. [Epub ahead of print] PMID:
18802031
Article Published Date
: Sep 18, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (American)
Diseases
:
Colitis: Pseudomembranous
,
Ulcerative Colitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Nitric Oxide Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.
Nov 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID:
29182579
Article Published Date
: Nov 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
[+]
Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2014 ;4:6234. Epub 2014 Aug 29. PMID:
25167935
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Raspberry
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins from black chokeberry delayed aging-related degenerative changes of the brain.
Jul 25, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Jul 26 ;65(29):5973-5984. Epub 2017 Jul 12. PMID:
28657734
Article Published Date
: Jul 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
Diseases
:
Aging: Brain
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Anti-diabetic effect of ramulus mori polysaccharides, isolated from Morus alba L., on STZ-diabetic mice through blocking inflammatory response and attenuating oxidative stress.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2013 May ;16(1):93-9. Epub 2013 Apr 6. PMID:
23566811
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Mulberry
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hypoglycemic Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
,
Polysaccharides
[+]
Anti-hyperuricemic and anti-gouty arthritis activities of polysaccharide purified from Lonicera japonica.
Feb 14, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Feb 15 ;123:801-809. Epub 2018 Nov 13. PMID:
30445085
Article Published Date
: Feb 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Hyperuricemia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Uricosuric Agents
Additional Keywords
:
Polysaccharides
[+]
Anti-Inflammatory activity and chemical analysis of different fractions from Solidago chilensis inflorescence.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:7612380. Epub 2021 Oct 29. PMID:
34745422
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Goldenrod
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Nitric Oxide Inhibitor
[+]
Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L.
Aug 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Aug 22 ;190:142-58. Epub 2016 Jun 4. PMID:
27269390
Article Published Date
: Aug 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Lavender
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Inflammatory Bowel Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anti-inflammatory activity of patchouli alcohol isolated from Pogostemonis Herba in animal models.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2011 Dec ;82(8):1295-301. Epub 2011 Sep 19. PMID:
21958968
Article Published Date
: Nov 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Patchouli
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:6874692. Epub 2018 Oct 11. PMID:
30405742
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway.
Jul 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2021 Aug ;140:111749. Epub 2021 May 28. PMID:
34058437
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Psychedelics:All
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Anti-inflammatory and vasorelaxant effects induced by an aqueous aged black garlic extract supplemented with vitamins D, C, and B12 on cardiovascular system.
Apr 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2023 Apr 6 ;12(7). Epub 2023 Apr 6. PMID:
37048379
Article Published Date
: Apr 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
,
Vitamin B12
,
Vitamin C
,
Vitamin D
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vasoprotective
[+]
Anti-inflammatory effects of deuterium-depleted water plus Rosa damascena essential oil via cyclooxygenase-2 pathway.
Jan 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Pharm Sci. 2020 Feb ;17(1):99-107. Epub 2020 Feb 19. PMID:
32454767
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Rose
,
Water: Deuterium Depleted
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Essential Oils
[+]
Anti-inflammatory effects of eriocitrin against the dextran sulfate sodium-induced experimental colitis in murine model.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Nov ;33(11):e22400. Epub 2019 Oct 8. PMID:
31593355
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Inflammation
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory mechanisms could be involved in pomegranate-mediated prevention of breast cancer.
Apr 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Apr 28 ;9(5). Epub 2017 Apr 28. PMID:
28452959
Article Published Date
: Apr 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Heat Shock Protein Down-Regulation
[+]
Anti-inflammatory, antioxidant and anti-apoptotic activity of diosmin in acetic acid-induced ulcerative colitis.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2018 Jan ;37(1):78-86. Epub 2017 Feb 23. PMID:
29187079
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-neuroinflammatory effect of the ethanolic extract of black ginseng.
Oct 17, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Oct 18 ;24(20). Epub 2023 Oct 18. PMID:
37894998
Article Published Date
: Oct 17, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-nociceptive effect of patchouli alcohol.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2019 Jun ;25(6):454-461. Epub 2017 Aug 9. PMID:
28795389
Article Published Date
: May 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Patchouli
Diseases
:
Hyperalgesia
Pharmacological Actions
:
Analgesics
,
Antinoceceptive
,
Cyclooxygenase 2 Inhibitors
[+]
Anti-ulcerative effects of wogonin on ulcerative colitis induced by dextran sulfate sodium.
Jan 18, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2022 Jan 19. Epub 2022 Jan 19. PMID:
35044701
Article Published Date
: Jan 18, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Wogonin
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastrointestinal Agents
,
Nrf2 activation
[+]
Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.
Apr 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Biol Sci. 2018 May ;25(4):747-754. Epub 2016 Oct 13. PMID:
29740240
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antiosteoarthritic effect of morroniside in chondrocyte inflammation and destabilization of medial meniscus-induced mouse model.
Mar 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Mar 15 ;22(6). Epub 2021 Mar 15. PMID:
33804203
Article Published Date
: Mar 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Dogwood
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Postaglandin PGE2 downregulation
Additional Keywords
:
Plant Extracts
[+]
Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl4-induced hepatotoxicity
Jan 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2020 Feb ;19(2):1313-1321. Epub 2019 Dec 19. PMID:
32010304
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antitumor activity of enzymatically hydrolyzed Ganoderma lucidum polysaccharide on U14 cervical carcinoma-bearing mice.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419869489. PMID:
31462112
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Polysaccharides
[+]
Antrodia camphorata extract, when combined with anti-tumor agents, showed adjuvant antiproliferative effects on multi-drug resistant hepatoma.
Aug 13, 2008
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2008 Aug 13;118(3):387-95. Epub 2008 May 7. PMID:
18571350
Article Published Date
: Aug 13, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Antrodia camphorata
Diseases
:
Cancers: Multi-Drug Resistant
,
Liver Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Cell cycle arrest
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Apigenin and myricetin exhibited a protective and promising preventive strategy against cisplatin-induced nephrotoxicity.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):766-774. PMID:
28064632
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Myricetin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin, a dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation in mice.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Arthritis Res Ther. 2009;11(2):R59. Epub 2009 Apr 30. PMID:
19405952
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Autoimmune Diseases
,
Lupus Erythematosus: Systemic
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2019 ;16:49. Epub 2019 Jul 26. PMID:
31372176
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pineapple
,
Vinegar
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Apple polyphenols extract (APE) improves colon damage in a rat model of colitis.
Feb 28, 2012
Click here to read the entire abstract
Pubmed Data
: Dig Liver Dis. 2012 Feb 28. Epub 2012 Feb 28. PMID:
22381211
Article Published Date
: Feb 28, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Colitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apples rich polyphenols reduce colonic inflammation in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(11):1620-8. Epub 2009 Jul 22. PMID:
19622193
Article Published Date
: Dec 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammatory Bowel Diseases
,
Irritable Bowel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Arctigenin exerts protective effects against myocardial infarction.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar ;17(3):4839-4845. Epub 2018 Jan 10. PMID:
29328478
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Heme oxygenase-1 up-regulation
Additional Keywords
:
Anti-Inflammatory Agents
,
Antioxidants
,
Arctigenin
,
Myocardial Infarction
[+]
Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2023 Jan ;114:109529. Epub 2022 Dec 6. PMID:
36481528
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Insulin Sensitizers
,
Interleukin-10 upregulation
[+]
Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration.
Dec 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Exp Ther. 2001 Dec;299(3):832-9. PMID:
11714866
Article Published Date
: Dec 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Alcoholic Liver Disease
,
Inflammation
,
Liver Fibrosis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aromatic-turmerone ameliorates DSS-induced ulcerative colitis via modulating gut microbiota in mice.
Jul 05, 2022
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2022 Jul 6. Epub 2022 Jul 6. PMID:
35794287
Article Published Date
: Jul 05, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Turmerones
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastrointestinal Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Artemisia extracts were mucoprotective by attenuating stress related mucosal damages.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2015 Mar ;56(2):132-42. Epub 2014 Nov 28. PMID:
25759519
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Artemisia asiatica
Diseases
:
Gastrointestinal Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Nrf2 activation
Additional Keywords
:
Dose Response
[+]
Artesunate affords protection against aspirin-induced gastric injury.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2018 Apr ;70(2):390-397. Epub 2017 Jun 15. PMID:
29397336
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Ulcer Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Natural Substances Versus Drugs
Problem Substances
:
Aspirin
[+]
Artesunate suppresses inflammation and oxidative stress in a rat model of colorectal cancer.
Aug 29, 2019
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2019 Aug 30. Epub 2019 Aug 30. PMID:
31471932
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Ascorbic acid contributes to the reduction of oxidative stress and inflammatory response in DSS-induced colitis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(11):20245-53. Epub 2015 Nov 15. PMID:
26884937
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Gastrointestinal Inflammation
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Asiatic acid alleviates LPS-induced acute kidney injury.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2022 Dec ;170:113468. Epub 2022 Oct 14. PMID:
36244460
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Nrf2 activation
,
Renoprotective
[+]
Asiatic acid is a potent nutraceutical agent against the progression of Parkinson's disease.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Apr ;7(4):1999-2005. PMID:
26999333
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin could be a promising agent for atopic dermatitis by inhibition of NF-κB signalling.
Sep 07, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2017 Sep 8. Epub 2017 Sep 8. PMID:
28887839
Article Published Date
: Sep 07, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin exhibits anti-inflammatory and anti-cancer activity in a rat model of colon cnacer.
Apr 01, 2011
Click here to read the entire abstract
Pubmed Data
: Invest New Drugs. 2011 Apr;29(2):207-24. Epub 2009 Oct 30. PMID:
19876598
Article Published Date
: Apr 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Colorectal Cancer
,
Inflammation
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Astaxanthin had an anti-depressant effect on diabetic mice.
Dec 21, 2016
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2016 Dec 22. Epub 2016 Dec 22. PMID:
28017669
Article Published Date
: Dec 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Depression
,
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Prophylactic Agents
[+]
Astaxanthin significantly suppressed the occurrence of esophageal cancer.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2019 ;12:5087-5096. Epub 2019 Jul 1. PMID:
31308688
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Astilbin ameliorates cisplatin-induced nephrotoxicity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Apr ;114:227-236. Epub 2018 Feb 20. PMID:
29471006
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID:
27816726
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Aspirin
[+]
Astragaloside IV suppresses inflammatory mediator production in synoviocytes and collagen‑induced arthritic rats.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2016 Apr ;13(4):3289-96. Epub 2016 Feb 22. PMID:
26936538
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Atractylodes macrocephala or Taraxacum herba extracts can be considered natural agents that can prevent inflammatory bowel disease relapse.
Sep 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Sep 15 ;11(5):655-666. PMID:
28651306
Article Published Date
: Sep 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bai Zhu
,
Dandelion
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Heme oxygenase-1 up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
,
Risk Reduction
,
Superiority of Natural Substances versus Drugs
[+]
Avocado may be used as a promising therapeutic against inflammatory bowel diseases.
Jan 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Jan 5 ;20(1). Epub 2019 Jan 5. PMID:
30621304
Article Published Date
: Jan 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Avocado
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
STAT3 Inhibitor
[+]
Bachu mushroom polysaccharide alleviates colonic injury by modulating the gut microbiota.
Dec 31, 2021
Click here to read the entire abstract
Pubmed Data
: Comput Math Methods Med. 2022 ;2022:1353724. Epub 2022 Mar 14. PMID:
35371288
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Mushrooms: All
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastrointestinal Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bee venom alleviated edema and pain in monosodium urate crystals-induced gouty arthritis.
Sep 15, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxins (Basel). 2021 Sep 16 ;13(9). Epub 2021 Sep 16. PMID:
34564665
Article Published Date
: Sep 15, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Benzyl isothiocyanate and sulforaphane protect against initiation of pancreatic carcinogenesis in hamsters.
Sep 28, 2006
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2006 Sep 28;241(2):275-80. Epub 2006 Jan 4. PMID:
16386831
Article Published Date
: Sep 28, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Benzyl isothiocyanate
,
Sulforaphane
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Isothiocyanates
,
Stilbenes
[+]
Berberine attenuates arthritis in adjuvant-induced arthritis.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Feb 20. Epub 2019 Feb 20. PMID:
30796904
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-17 downregulation
,
NF-kappaB Inhibitor
[+]
Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats.
Aug 22, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Aug 23 ;95:175-185. Epub 2017 Aug 23. PMID:
28843149
Article Published Date
: Aug 22, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
,
Pancreato Protective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Diabetes Mellitus: Type 1
[+]
Berberine has a preventive effect on experimental colon cancer.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(20):2768-73. PMID:
21246838
Article Published Date
: Oct 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Berberine prevents non-alcoholic steatohepatitis-derived hepatocellular carcinoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2019 ;11(5):2668-2682. Epub 2019 May 15. PMID:
31217846
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Liver Cancer
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Berberine reduces neuroglia activation and inflammation in streptozotocin-induced diabetic mice.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419866379. PMID:
31337260
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine suppresses growth and metastasis of endometrial cancer cells.
Jun 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1287-1293. Epub 2018 May 7. PMID:
29864910
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Prostaglandin PGE2 downregulation
[+]
Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion.
Sep 02, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2021 Sep 3:112122. Epub 2021 Sep 3. PMID:
34489150
Article Published Date
: Sep 02, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
[+]
Beta-caryophyllene constitutes an alluring therapeutic molecule towards the treatment of multiple sclerosis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Apr 1 ;18(4). Epub 2017 Apr 1. PMID:
28368293
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Beta-Caryophyllene
Diseases
:
Inflammation: Brain
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Cannabinoid Receptors
[+]
Betulinic acid exerts antigenotoxic and anticarcinogenic activities via inhibition of COX-2 and PCNA in rodents.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2021 Dec ;35(12):e22917. Epub 2021 Sep 19. PMID:
34541749
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Colorectal Cancer
,
Inflammation
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antimutagenic Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
[+]
Black Adzuki bean attenuates high-fat diet-induced colon inflammation.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Apr ;20(4):367-375. PMID:
28406732
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Aduki bean
Diseases
:
Colitis
,
High Fat Diet
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Black ginseng-enriched Chong-Myung-Tang extracts improve spatial learning behavior.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2017 Apr ;41(2):151-158. Epub 2016 Mar 25. PMID:
28413319
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginseng
Diseases
:
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Blueberry treatment administered before and/or after lipopolysaccharide stimulation attenuates inflammation and oxidative stress.
Jan 31, 2023
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2023 Feb ;26(2):127-137. Epub 2022 Jan 4. PMID:
36692990
Article Published Date
: Jan 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Brain: Microglial Activation
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Boosting memory by an ergothioneine-rich Hericium erinaceus primordium extract.
Jan 27, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biology (Basel). 2023 Jan 28 ;12(2). Epub 2023 Jan 28. PMID:
36829475
Article Published Date
: Jan 27, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
[+]
Boswellia serrata extracts exhibits potential as a therapeutic agent for treating osteoarthritis.
Sep 29, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prev Nutr Food Sci. 2023 Sep 30 ;28(3):285-292. PMID:
37842260
Article Published Date
: Sep 29, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Osteoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Boswellia serrate extract has great potential to suppress colon tumorigenesis.
Feb 27, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2017 Feb 28. Epub 2017 Feb 28. PMID:
28245338
Article Published Date
: Feb 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Boswellic acid inhibits growth and metastasis of human colorectal cancer.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2012 May 1 ;130(9):2176-84. Epub 2011 Sep 12. PMID:
21702037
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
,
Frankincense
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model).
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID:
22066019
Article Published Date
: Jan 01, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Boswellia
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Both indole-3-carbinol and myo-inositol inhibit the development of vinyl carbamate induced pulmonary adenocarcinoma in mice.
Jan 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2010 Feb ;31(2):239-45. Epub 2009 Jul 22. PMID:
19625346
Article Published Date
: Jan 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Indole-3-Carbinol
,
Myo-inositol
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
Problem Substances
:
Vinyl Carbamate
[+]
C-phycocyanin relieved symptoms associated with cyclophosphamide-induced cystitis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:8424872. Epub 2019 Jul 29. PMID:
31467580
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Spirulina
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Cystitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
Additional Keywords
:
C-phycocyanin
[+]
C. asiatica treatment helps to prevent cerebral damage and maintain near normal cerebral function in diabetes.
Jun 24, 2020
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2020 Jun 25. Epub 2020 Jun 25. PMID:
32588370
Article Published Date
: Jun 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
C. obtusa essential oil may constitute a novel source of anti-inflammatory treatments.
Jun 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2013 Jul ;8(1):255-9. Epub 2013 May 8. PMID:
23652412
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Japanese cypress
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Oils
[+]
Caffeic acid phenethyl ester, a compound found within propolis causes regression of experimental endometriosis.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Reprod Sci. 2007 Apr;14(3):270-9. PMID:
17636241
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
,
Caffeic acid phenethyl ester
Diseases
:
Endometriosis
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
[+]
Camel milk attenuates rheumatoid arthritis in animals.
Sep 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2017 Sep 20 ;43(2):540-552. Epub 2017 Sep 20. PMID:
28930753
Article Published Date
: Sep 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 upregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol could be used to prevent experimental colitis in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Mol Med (Berl). 2009 Nov ;87(11):1111-21. Epub 2009 Aug 20. PMID:
19690824
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Colitis
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
[+]
Cardioprotective effect of silymarin nanoemulsion on 5-fluorouracil-induced cardiotoxicity.
Apr 10, 2022
Click here to read the entire abstract
Pubmed Data
: Arch Pharm (Weinheim). 2022 Apr 11:e2200060. Epub 2022 Apr 11. PMID:
35411625
Article Published Date
: Apr 10, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Silibinin
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia.
Feb 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2021 Mar ;135:111197. Epub 2021 Feb 1. PMID:
33433362
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
Diseases
:
Prostatic Hyperplasia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
[+]
Carnosol protects against spinal cord injury through Nrf-2 upregulation.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Recept Signal Transduct Res. 2016 ;36(1):72-8. Epub 2015 Jul 6. PMID:
26791582
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Carnosol
Diseases
:
Oxidative Stress
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Carrot seeds contain phytochemicals capable of inhibiting inflammatory enzymes.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2007 Jun;28(6):1188-96. Epub 2006 Dec 6. PMID:
13680840
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Cyclooxygenase Inhibitors
[+]
Carvacrol can be used as a protective agent against benzo(a)pyrene-induced lung toxicity and inflammation.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2017 Jan 1:960327117735572. Epub 2017 Jan 1. PMID:
29019276
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
Problem Substances
:
Benzo(a)pyrene
[+]
Carvacrol preserves antioxidant status and attenuates kidney fibrosis.
Oct 16, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Oct 17 ;13(20):10587-10600. Epub 2022 Oct 17. PMID:
36156620
Article Published Date
: Oct 16, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Nicotinamide adenine dinucleotide (NADH)
Diseases
:
Inflammation
,
Kidney Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Carvacrol prevents the proconvulsant effect of LPS possibly through the inhibition of the COX-2 increased activity.
Jan 11, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2018 12 ;33(6):2045-2050. Epub 2018 Sep 18. PMID:
30229386
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Seizures
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Celastrol ameliorates osteoarthritis via regulating TLR2/NF-κB signaling pathway.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:963506. Epub 2022 Aug 10. PMID:
36034791
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Celastrol
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
[+]
Chamaecyparis obtusa essential oil has anti-inflammatory and anti-nociceptive effects on arthritis in rats.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2015 ;80(1):203-9. Epub 2015 Aug 19. PMID:
26581235
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Japanese cypress
Diseases
:
Arthritis
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Antinoceceptive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Essential Oils
[+]
Chemical characterization of different extracts from Artemisia annua and their antioxidant, enzyme inhibitory and anti-inflammatory properties.
Jul 31, 2023
Click here to read the entire abstract
Pubmed Data
: Chem Biodivers. 2023 Aug ;20(8):e202300547. Epub 2023 Jul 17. PMID:
37306942
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Mugwort
Diseases
:
Alcohol Toxicity
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chemopreventive effects of Eryngium foetidum L. leaves on COX-2 reduction in mice induced colorectal carcinogenesis.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 ;68(1):144-53. Epub 2016 Jan 15. PMID:
26771664
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thistle
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Phytotherapy
[+]
Chinese skullcap (Scutellaria baicalensis) significantly improves functional recovery from spinal cord injury in rats by inhibiting inflammation and oxidative stress after injury.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2009 Aug;110(4):1276-87. Epub 2009 Jun 10. PMID:
19519665
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chinese Skullcap
Diseases
:
Brain: Microglial Activation
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chrysin alleviates cerebral ischemia-reperfusion injury
Feb 28, 2023
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2023 Mar ;48(6):1597-1605. PMID:
37005848
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
[+]
Chrysin has a protective effect against cyclophosphamide -induced hepatorenal toxicity.
Oct 15, 2019
Click here to read the entire abstract
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 16. Epub 2019 Oct 16. PMID:
31620822
Article Published Date
: Oct 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cyclophosphamide
[+]
Cloudy apple juice potentiates hepatoprotection during experimental liver injury.
Aug 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Aug 21 ;140:1006-1017. Epub 2019 Aug 21. PMID:
31445146
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
[+]
Cocoa may merit further clinical investigation as a chemopreventive agent that helps prevent colitis-associated cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biofactors. 2015 Jan-Feb;41(1):1-14. Epub 2014 Dec 24. PMID:
25545372
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Nrf2 activation
[+]
Cocoa polyphenols may inhibit tumor promotion through antioxidant and antiinflammatory mechanisms.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 May;136(5):1150-5. PMID:
16614396
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Tumors
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Coix lachryma-jobi extract ameliorates inflammation and oxidative stress in a complete Freund's adjuvant-induced rheumatoid arthritis model.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2019 Dec ;57(1):792-798. PMID:
31747811
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Adlay
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory responses.
Jan 18, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2018 Jan 19 ;18(1):20. Epub 2018 Jan 19. PMID:
29351747
Article Published Date
: Jan 18, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coptis chinensis
,
Pelargonium sidoides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):1022-1031. PMID:
35635784
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Puerarin
,
Tanshinone IIA
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
[+]
Combination of white tea and peppermint demonstrated synergistic antibacterial and anti-inflammatory activities.
Oct 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2020 Oct 15. Epub 2020 Oct 15. PMID:
33058206
Article Published Date
: Oct 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Peppermint
,
White Tea
Diseases
:
Staphylococcal Infections
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
[+]
Combinational treatment effect of tetrahydrocurcumin and celecoxib on cervical cancer cell-induced tumor growth and tumor angiogenesis.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: J Med Assoc Thai. 2016 Jul ;99 Suppl 4:S23-31. PMID:
29916670
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Tetrahydrocurcumin
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Angiogenic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Compounds present in grape juice could reduce the inflammatory effects induced by experimental colitis.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2014 Mar ;37(2):819-27. Epub 2014 Feb 26. PMID:
24637249
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Colitis
,
DNA damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Considering the effect of Rosa damascen essential oil on oxidative stress and COX-2 gene expression in the liver of septic rats.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Pharm Sci. 2019 Dec ;16(4):416-424. Epub 2019 Nov 11. PMID:
32454744
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Oxidative Stress
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Essential Oils
[+]
Cordyceps cicadae NTTU 868 mycelia fermented with deep ocean water minerals prevents D-galactose-induced memory deficits.
Apr 18, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2023 Apr 19 ;15(8). Epub 2023 Apr 19. PMID:
37111188
Article Published Date
: Apr 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Medicinal Mushrooms
Diseases
:
Aging
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cordyceps militaris protected against chronic kidney disease progression.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:7850863. Epub 2019 Mar 31. PMID:
31049139
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
COX2 expression in HPV16-induced lesions may be modulated by nutraceuticals.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2018 03 ;38(3):1461-1466. PMID:
29491072
Article Published Date
: Dec 31, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
,
Rutin
Diseases
:
Human Papillomavirus (HPV)
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Crocetin supplementation in the MCA mice also showed protection against cervical cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2015 ;2015:829513. Epub 2015 Mar 22. PMID:
25874230
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Crocin potentiates the suppressive effects of sorafenib on tumor growth.
Aug 10, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2023 Aug 11 ;15(16). Epub 2023 Aug 11. PMID:
37627094
Article Published Date
: Aug 10, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Chemosensitizer
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
Additional Keywords
:
Chemothapeutic Synergy: Sorafenib
[+]
Crocin, a carotenoid fround within Gardenia jasminoides and Crocus sativus (Safron) has significant anti-inflammatory activity.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8325-30. PMID:
19754168
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Gardenia
,
Saffron
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Cyclooxygenase Inhibitors
,
Prostaglandin Antagonists
[+]
Cryptotanshinone ameliorates hemorrhagic shock-induced liver injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Folia Histochem Cytobiol. 2023 ;61(2):109-122. PMID:
37435898
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Hemorrhagic Shock
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Curcumin ameliorates doxorubicin-induced cardiotoxicity.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2018 Feb ;32(2). Epub 2018 Jan 5. PMID:
29315967
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Curcumin ameliorates experimentally induced ulcerative colitis.
Mar 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2007 Mar;7(3):333-42. Epub 2006 Dec 18. PMID:
17276891
Article Published Date
: Mar 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colitis
,
Ulcerative Colitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin attenuated glucose intolerance and insulin resistance through its antioxidant and anti-inflammatory effects.
Dec 19, 2015
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2015 Dec 20. Epub 2015 Dec 20. PMID:
26713546
Article Published Date
: Dec 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Inflammation
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin can enhance postsynaptic electrical reactivity and cell viability in intact neural circuits with antidepressant-like effects.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2017 ;2017:6280925. Epub 2017 Jan 11. PMID:
28167853
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Antidepressive Agents
,
CURCUMIN
,
Cyclooxygenase 2 Inhibitors
,
Depression
[+]
Curcumin has therapeutic effects in chemically-induced colitis.
Jun 28, 2006
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2006 Jun 28;12(24):3848-53. PMID:
16804969
Article Published Date
: Jun 28, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin inhibits NF-kappaB activation and reduces the severity of experimental fatty liver in mice.
Dec 01, 2003
Click here to read the entire abstract
Pubmed Data
: Mech Ageing Dev. 2003 Dec;124(10-12):1025-34. PMID:
15582125
Article Published Date
: Dec 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Fatty Liver
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Curcumin inhibits prostate cancer tumors.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Peptides. 2009 Dec;30(12):2357-64. Epub 2009 Sep 20. PMID:
19772879
Article Published Date
: Dec 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2006 Aug;6(8):1233-42. Epub 2006 Apr 7. PMID:
16782535
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Curcumin may have therapeutic value in colon cancer prevention.
Oct 28, 1999
Click here to read the entire abstract
Pubmed Data
: Oncogene. 1999 Oct 28;18(44):6013-20. PMID:
10557090
Article Published Date
: Oct 28, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin might be useful in the chemoprevention of colorectal cancer in individuals consuming an high-protein diet.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2015 Aug ;35(8):726-35. Epub 2015 Jun 1. PMID:
26094212
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer: Prevention
,
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin potentiated significant increase in Nrf2 activation. It restored activity of phase-II antioxidant enzymes like GST, GR, NQO1, and tumour suppressor p53 level.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(4):e0124000. Epub 2015 Apr 10. PMID:
25860911
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Liver Cancer
,
Liver Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
MicroRNA modulator
,
Nrf2 activation
,
Tumor Suppressor Protein p53 Upregulation
[+]
Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2009 Dec 1;69(23):8958-66. Epub 2009 Nov 10. PMID:
19903839
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords
:
Drug Synergy
[+]
Curcumin prevents colon carcinogenesis.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1999 Apr;20(4):641-4. PMID:
10223193
Article Published Date
: Apr 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
,
Nitric Oxide Inhibitor
[+]
Curcumin protects against necrotizing enterocolitis in neonatal rats.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Dang Dai Er Ke Za Zhi. 2010 Feb;12(2):132-6. PMID:
20199731
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Infant Infections
,
Necrotising enterocolitis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin reduces oxidative and nitrative DNA damage associated with fluke infection.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2009 Oct;53(10):1316-28. PMID:
19753608
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
DNA damage
,
Flukes
,
Oxidative Stress
,
Parasitic Diseases
Pharmacological Actions
:
Antimutagenic Agents
,
Antiparasitic Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2019 07 ;127:432-448. Epub 2019 Apr 2. PMID:
30951849
Article Published Date
: Dec 31, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Curcumin retards the growth of intestinal polyps in a mouse model of familial adenomatous polyposis.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID:
16387490
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Familial Adenomatous Polyposis
,
Intestinal Polyps
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Curcumin reverses neurochemical, histological and immuno-histochemical alterations in the model of global brain ischemia.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2017 Jan ;7(1):14-23. Epub 2016 Feb 11. PMID:
28053883
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin sensitizes human colorectal cancer to capecitabine.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2009 Nov 1 ;125(9):2187-97. PMID:
19623659
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Curcumin works synergistically with paclitaxel to inhibit breast cancer cell metastasis to the lung in a mouse model.
Oct 15, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2005 Oct 15;11(20):7490-8. PMID:
16243823
Article Published Date
: Oct 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Drug: Paclitaxel
,
Drug-Plant-Vitamin Synergies
[+]
Cyanidin-3-O-glucoside exerts pulmonary protective effects on CLP-induced ALI rats.
Jun 11, 2015
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2015 Jun 12. Epub 2015 Jun 12. PMID:
26152793
Article Published Date
: Jun 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cyanidin 3-glucoside
Diseases
:
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Mitochondrial Superoxide Dismutase Upregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2017 Apr ;15(4):2339-2346. Epub 2017 Feb 22. PMID:
28260017
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
D-Limonene
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Postaglandin PGE2 downregulation
[+]
D-limonene suppresses doxorubicin-induced oxidative stress and inflammation.
Mar 31, 2014
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2014 Apr ;239(4):465-76. Epub 2014 Feb 28. PMID:
24586096
Article Published Date
: Mar 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
D-Limonene
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Daidzein attenuates abdominal aortic aneurysm through NF-κB, p38MAPK and TGF-β1 pathways.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2016 Jul ;14(1):955-62. Epub 2016 May 18. PMID:
27222119
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Daidzein
,
Isoflavones
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Demethoxycurcumin may decrease COX-2 expression and improve endothelial function in hypertension.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2016 ;2016:9045736. Epub 2016 Dec 25. PMID:
28105253
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Demethoxycurcumin
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
[+]
Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.
Jul 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jul 5 ;758:188-96. Epub 2015 Apr 8. PMID:
25863259
Article Published Date
: Jul 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary administration of garcinol effectively reduced the tumor size and incidence in the mouse colon.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2014 Sep ;58(9):1820-9. Epub 2014 Jul 1. PMID:
24981158
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garcinia indica
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
,
Cyclin D1 Down-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice.
May 20, 2011
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2011 May 20. Epub 2011 May 20. PMID:
21621527
Article Published Date
: May 20, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Colitis
,