Glutathione Upregulation

Name	AC	CK
Whey	9	48
Sulforaphane	4	22
Chokeberry	2	20
Astaxanthin	4	16
Selenium	3	14
Probiotics	2	12
Coffee	2	11
Bee Propolis	1	10
Glutathione	1	10
Grape Seed Extract	1	10
MSM (Methylsulfonylmethane)	1	10
Prebiotics	1	10
Sesamol	4	8
Flavonoids	2	6
Ginger	3	6
Chrysin	2	4
Curcumin	2	4
Melatonin	2	4
Reishi Mushroom	2	4
Resveratrol	3	4
Saffron	2	4
Arginine	2	3
Barley	2	3
EGCG (Epigallocatechin gallate)	2	3
Zinc	2	3
6-Shogaol	1	2
Bacopa	1	2
Biochanin A	1	2
Blueberry	1	2
Catechin	1	2
Chlorella (Algae)	1	2
Cinnamon	1	2
Coconut Oil	1	2
Coenzyme Q10	1	2
Crocin	1	2
Cysteine (see N-Acetylcysteine)	1	2
Dandelion	2	2
Ellagic Acid	1	2
False Black Pepper	1	2
Ferulic acid	1	2
Fig	1	2
Garlic	1	2
Gingerol	1	2
Gotu Kola	1	2
Green Tea	1	2
Hesperidin	1	2
Holy Basil	1	2
Honokiol	1	2
Hydrogen: Molecular	1	2
Leonurine	1	2
Litchi	1	2
Loquat Seeds	1	2
Mangosteen	1	2
Moringa oleifera	1	2
Nettle	1	2
Olive leaf extract	1	2
Omega-3 Fatty Acids	1	2
Onion	1	2
Parsley	1	2
Pine Bark Extract	1	2
Pueraria mirifica	1	2
Pycnogenol (Pine Bark)	1	2
Quince	1	2
Rhodiola (Tibetan Ginseng)	1	2
Rosemary	1	2
Taurine	1	2
Thymoquinone	1	2
Turmeric	1	2
Virgin Coconut Oil	1	2
Vitamin B-6	1	2
Apple Polyphenols	1	1
Cinnamaldehyde	1	1
NAC (N-acetyl-L-cysteine)	1	1
Naringenin	1	1
P-Coumaric Acid	1	1
Polyphenols	1	1
Quercetin	1	1
Silibinin	1	1
Silymarin	1	1
Stilbenes	1	1
Vitamin E: alpha tocopherol	1	1
Broccoli	1	0
Nexrutine (Phellodendrom)	1	0
Sprouts	1	0

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Astaxanthin appears to be an effective agent to increase endogenous antioxidant status.Oct 04, 2021

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Pubmed Data : Int J Sport Nutr Exerc Metab. 2021 Oct 5:1-8. Epub 2021 Oct 5. PMID: 34611051

Article Published Date : Oct 04, 2021

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Muscle Soreness: Exercise-Induced, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation

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Breathing exercises increased superoxide dismutase and glutathione activities and decreased malondialdehyde content.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Iran Red Crescent Med J. 2016 Sep ;18(9):e31314. Epub 2016 Jul 17. PMID: 28144458

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2023 Sep ;27(18):8324-8329. PMID: 37782149

Article Published Date : Aug 31, 2023

Study Type : Animal Study

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Substances : Omega-3 Fatty Acids

Diseases : Oxidative Stress

Therapeutic Actions : Exercise

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation

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Astaxanthin attenuates environmental tobacco smoke-induced cognitive deficits.Jan 02, 2019

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Fresh nettle leaves are a natural protective herb that may play a beneficial role in the prevention of Hg intoxication.Nov 30, 2015

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Pubmed Data : Vet World. 2015 Dec ;8(12):1458-65. PMID: 27047060

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : Nettle

Diseases : Mercury Poisoning

Pharmacological Actions : Glutathione Upregulation

Additional Keywords : Herbal Teas, Methylmercury

Problem Substances : Mercury

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Ganoderma Lucidum from red mushroom attenuates formaldehyde-induced liver damage.Sep 26, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biology (Basel). 2020 Sep 27 ;9(10). Epub 2020 Sep 27. PMID: 32992510

Article Published Date : Sep 26, 2020

Study Type : Animal Study

Additional Links

Substances : Reishi Mushroom

Diseases : Chemically-Induced Liver Damage, Formaldehyde Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , Hepatoprotective

Problem Substances : Formaldehyde Releasers

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Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain. Jan 01, 2012

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Pubmed Data : Pharmacognosy Res. 2012 Jan ;4(1):27-32. PMID: 22224058

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

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Pubmed Data : Life Sci. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27436544

Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1111-21. Epub 2008 Oct 2. PMID: 18832452

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Probiotics

Diseases : Pancreatitis

Pharmacological Actions : Glutathione Upregulation

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Protective effects of triple fermented barley extract on indomethacin-induced gastric mucosal damage in rats.Feb 19, 2019

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Pubmed Data : BMC Complement Altern Med. 2019 Feb 20 ;19(1):49. Epub 2019 Feb 20. PMID: 30786935

Article Published Date : Feb 19, 2019

Study Type : Animal Study

Additional Links

Substances : Barley

Diseases : Gastric Ulcer, Lipid Peroxidation

Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective, Glutathione Upregulation

Additional Keywords : Plant Extracts

Problem Substances : Indomethacin

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Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Res Notes. 2017 Feb 1 ;10(1):77. Epub 2017 Feb 1. PMID: 28143589

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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Virgin coconut oil has the potential to be used as a memory enhancer.Nov 30, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutrients. 2017 Nov 16 ;9(11). Epub 2017 Nov 16. PMID: 29144408

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Pubmed Data : J Ethnopharmacol. 2011 Jan 27;133(2):834-42. Epub 2010 Nov 11. PMID: 21075189

Article Published Date : Jan 27, 2011

Study Type : In Vitro Study

Additional Links

Substances : Dandelion

Diseases : Glutathione Deficiency , Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

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Dandelion extracts especially leaf and flower extracts are potent protective agents against UVB damage.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2015 ;2015:619560. Epub 2015 Oct 20. PMID: 26576225

Protective effects of silibinin on LPS-induced inflammation in human periodontal ligament cells.Dec 31, 2021

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Pubmed Data : Exp Dermatol. 2010 Feb;19(2):137-44. Epub 2009 Jun 23. PMID: 19558496

Article Published Date : Feb 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Aging Skin, Glutathione Deficiency , Skin Diseases

Pharmacological Actions : Anticarcinogenic Agents, Glutathione Upregulation , NF-kappaB Inhibitor

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This review summarises the many health benefits of Sulforaphane as a antioxidant dietary supplement.May 04, 2015

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Pubmed Data : Recent Pat Endocr Metab Immune Drug Discov. 2015 May 5. Epub 2015 May 5. PMID: 25944116

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):949-54. PMID: 11535546

Article Published Date : Sep 01, 2001

Additional Links

Substances : Broccoli, Sprouts

Diseases : Prostate Cancer

Pharmacological Actions : Glutathione Upregulation

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Phellodendron amurense has the highest glutathione S-transferase activiting activity of 265 kinds of medicinal plants tested.Sep 01, 2006

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Pubmed Data : Peptides. 2006 Sep;27(9):2069-74. Epub 2006 Apr 19. PMID: 16624447

Article Published Date : Sep 01, 2006

Additional Links

Substances : Nexrutine (Phellodendrom)

Pharmacological Actions : Glutathione Upregulation

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Astaxanthin appears to be an effective agent to increase endogenous antioxidant status.Oct 04, 2021

Breathing exercises increased superoxide dismutase and glutathione activities and decreased malondialdehyde content.Dec 31, 2022

Changes in the glutathione system of erythrocytes due to enhanced formation of oxygen free radicals during short-term whole body cold stimulus.Dec 31, 1991

Coffee (especially dark roast) reduces body weight and restores red blood cell vitamin E and glutathione concentrations in healthy volunteers.Aug 02, 2011

Effects of synbiotic food consumption on metabolic status of diabetic patients.Mar 31, 2014

Grape seed extract for eight weeks had beneficial effects on the plasma GSH, MDA levels, and markers of insulin metabolism of female volleyball players.Aug 31, 2016

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.Oct 01, 2011

Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function.Dec 31, 2017

Pressurized whey protein isolate can increase lymphocyte glutathione levels by 24%Sep 01, 2007

Propolis as an adjuvant in the healing of human diabetic foot wounds.Dec 31, 2018

Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men.Feb 01, 2011

Supplementation with whey proteins persistently increased plasma glutathione levels in patients with advanced HIV-infection.Feb 01, 2002

These findings suggest that daily supplementation of 300 mg ABE might help boost GSH levels.Feb 01, 2023

This study demonstrated a significant increase in glutathione levels and improvement of cytoprotective targets following Aronia supplementation.Jan 02, 2023

Uric acid and glutathione levels are increased during short-term whole body cold exposure.Feb 28, 1994

Week-long oral administration of sulforaphane increased blood and thalamic glutathione levels in healthy human subjects.May 01, 2018

Whey protein concentrate supplementation can stimulate glutathione synthesis and, possibly, decrease the occurence of associated co-infections.Feb 01, 2006

Yoga participants had significantly greater improvement in reduced glutathione compared to controls. Jul 07, 2019

Flavonoid mixture inhibits Mycobacterium tuberculosis survival and infectivity.Feb 27, 2019

Melatonin alleviates renal injury in diabetic rats by regulating autophagy.Oct 31, 2023

6-Shogaol can alleviate allergic dermatitis-like skin lesions.Oct 31, 2016

Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice.Dec 31, 2016

Alpha mangostin attenuated hepatic steatosis in high fat-diet fed rats potentially through enhanced cellular antioxidant capacity.Dec 31, 2015

Antioxidant effect of omega-3 fatty acids on exercise-induced oxidative stress.Aug 31, 2023

Astaxanthin attenuates environmental tobacco smoke-induced cognitive deficits.Jan 02, 2019

Astaxanthin improves diabetic complications associated wtih dental pulp tissue. Nov 01, 2010

Astaxanthin restores the enzymatic antioxidant profile in salivary gland of alloxan-induced diabetic rats.Jul 01, 2010

Beneficial effect of the methanolic leaf extract of Allium hookeri on stimulating glutathione biosynthesis and preventing impaired glucose metabolism in type 2 diabetes.Jan 14, 2021

Biochanin A ameliorates arsenic-induced hepato- and hematotoxicity in rats.Jan 08, 2016

Blueberry attenuates liver injury in metabolic dysfunction-associated liver disease.Mar 31, 2023

Brahmi vati may be used to treat seizures associated with schizophrenia and related memory loss.Feb 28, 2018

Centella asiatica potential in alleviating the alterations caused by diabetes in testes.Jul 12, 2020

Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.Jul 07, 2011

Chrysin protects against free radical-mediated oxidative stress in rats with ethanol-induced liver injury. Jun 01, 2009

Cinnamon and rhodiola have significant blood sugar lowering and antioxidant activity.Jan 01, 2006

Coenzyme Q10 has a coloprotective effect against experimentally induced ulcerative colitis.Jan 02, 2017

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo, indicating its value for Parkinson disease. Mar 01, 2008

EGCG protects against muscle wasting disease, in a mouse model. Apr 14, 2010

Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats.Dec 31, 2012

Fresh nettle leaves are a natural protective herb that may play a beneficial role in the prevention of Hg intoxication.Nov 30, 2015

Ganoderma Lucidum from red mushroom attenuates formaldehyde-induced liver damage.Sep 26, 2020

Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain. Jan 01, 2012

Ginger protects against liver fibrosis.Jan 01, 2011

Green tea catechin prevents the decline of glutathione peroxidase activity and protein oxidative damage in aging mouse brain.Aug 01, 2007

Hesperidin and chrysin alleviated the renal injury induced by colistin via anti-oxidant and anti-inflammatory activities.Nov 30, 2018

Holy basil (O. sanctum) protects against radiation injury through modulating glutathione and antioxidant enzymes. Mar 01, 1999

Honokiol protects the kidney from renal ischemia and reperfusion injury.Sep 14, 2020

L-arginine protects against pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.Aug 01, 2005

Leonurine reduces oxidative stress and provides neuroprotection against ischemic injury.Sep 04, 2022

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Lychee pulp phenolics protect the liver against restraint stress-induced damage by scavenging free radicals and modulating mitochondrial dysfunction.Dec 31, 2015

Moringa oleifera prevents acetaminophen induced liver injury through restoration of glutathione level. Aug 01, 2008

N-acetylcysteine and thymoquinone have renoprotective effects of against the toxicity of fluoride via multiple mechanisms.Dec 31, 2017

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients.Feb 01, 2001

Parsley is effective in reducing stress-induced gastric injury by supporting the cellular antioxidant defence system.Dec 31, 2016

Photobiomodulation therapy reduces apoptotic factors and increases glutathione levels in a neuropathic pain model.Nov 30, 2016

Pinus massoniana bark extract treatment prevents hydrogen peroxide and carbon tetrachloride induced liver damage.Dec 31, 2009

Polysaccharides from Ganoderma lucidum played a positive protective role in the pulmonary fibrosis.Oct 31, 2016

Probiotics enhance glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis. Nov 01, 2008

Protective effects of triple fermented barley extract on indomethacin-induced gastric mucosal damage in rats.Feb 19, 2019

Pueraria mirifica and miroestrol as promising alternative medicine candidates for hormone replacement therapy of estradiol.Feb 28, 2013

Pycnogenol treatment attenuated α-chlorohydrin-induced spermatotoxicity through antioxidant and antiapoptotic effects.Feb 28, 2014

Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotectionJan 17, 2020

Quince and fig may increase the therapeutic index of doxorubicin.May 31, 2017

Rosemary attenuates radiation-induced toxicity.Oct 01, 2007

Saffron and crocin ameliorate prenatal valproic acid-induced autistic-like behaviors and brain oxidative stress in the male offspring rats.Sep 30, 2023

Selenium inhibits pancreatic cancer cell growth in hamsters. Jul 15, 1990

Glutathione Upregulation

View the Evidence:
110 Abstracts with Glutathione Upregulation Research