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Hepatoprotective
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596 Substances Researched for Hepatoprotective
Name
AC
CK
Focus
Curcumin
142
310
Coffee
11
108
Ginsenosides
49
85
Vitamin E
17
83
NAC (N-acetyl-L-cysteine)
25
80
Vitamin D
16
80
Vitamin C
31
75
Green Tea
20
64
Flavonoids
35
63
Thymoquinone
30
63
Turmeric
24
62
Garlic
19
60
Nigella sativa (aka Black Seed)
23
59
Resveratrol
32
59
Anthocyanins
26
56
Polyphenols
30
56
Probiotics
17
56
Berberine
29
54
Fermented Foods and Beverages
21
48
Peony
7
48
Silymarin
16
47
Milk Thistle
16
46
Omega-3 Fatty Acids
10
45
Melatonin
24
44
Astaxanthin
25
43
Quercetin
19
43
Spirulina
18
43
Fucoidan
18
42
Hydrogen Water
9
42
Ginger
20
39
Hydroxytyrosol
11
37
Saffron
9
35
Polyunsaturated Fatty Acids (PUFAs)
4
34
Puerarin
18
34
Lycopene
19
33
Moringa oleifera
18
33
Naringenin
18
32
Silibinin
15
32
Chrysin
16
31
Hesperidin
12
31
DHA (Docosahexaenoic Acid)
7
30
Pomegranate
16
30
Rose
17
30
Tanshinone IIA
9
30
Sulforaphane
13
29
Chlorogenic Acid
10
28
Flaxseed
6
28
Ginseng (Korean)
7
28
Blueberry
14
27
Luteolin
8
27
Alpha-Lipoic Acid
13
26
Artichoke
10
26
Fenugreek
9
26
Guduchi
5
26
Mangiferin
14
26
Blue Honeysuckle
13
25
Lactobacillus plantarum
13
25
Zataria multiflora
9
25
Crocin
12
24
EGCG (Epigallocatechin gallate)
14
24
Reishi Mushroom
8
24
Selenium
12
24
Apigenin
11
23
Chokeberry
12
23
Citrus naringin
13
23
Dandelion
12
23
Ginseng
12
23
Ginkgo biloba
12
22
Licorice
13
21
Olive Oil
7
21
Rosemary
11
21
Zinc
7
21
Chicory
6
20
Grape Seed Extract
10
20
Hibiscus sabdariffa
6
20
Pterostilbene
11
20
Tea: Black
1
20
Tea: Green
1
20
Ellagic Acid
10
19
Bilberry
5
18
Black Currant
5
18
Catechin
6
18
Honey
9
18
Lotus
11
18
Royal Jelly
10
18
Coenzyme Q10
9
17
Fisetin
9
17
Garden Cress (Lepidium sativum)
7
17
Honeysuckle
9
17
Lactobacillus rhamnosus GG
9
17
Mulberry
10
17
Olive leaf extract
9
17
Walnut
9
17
Asiatic Acid
9
16
Bee Propolis
8
16
Black Tea
8
16
Cryptoxanthin
5
16
Diosmin
8
16
Fucoxanthin
5
16
Grape
8
16
Lutein
5
16
Onion
4
16
Piperine
4
16
Yoghurt
4
16
Apple Polyphenols
8
15
Caffeic acid phenethyl ester
8
15
Carotenoids
4
15
Paeoniflorin
9
15
Shikonin
8
15
Betulinic acid
8
14
Broccoli
3
14
Chia
3
14
Genistein
8
14
Hawthorn
7
14
Lactobacillus casei
3
14
Magnesium
3
14
Paeonol
7
14
Rutin
8
14
Schisandra
8
14
Sea buckthorn
7
14
Strawberry
8
14
Sweet Potato: Purple
7
14
Ursolic Acid
8
14
Xanthohumol
8
14
Cannabidiol
7
13
Gingerol
7
13
Glycyrrhizin
7
13
L-Carnitine
3
13
Nobiletin
8
13
Beet
6
12
Camel Milk
6
12
Celery
6
12
Geraniol
6
12
Holy Basil
2
12
Radish
7
12
Turmeric: Fermented
2
12
White Tea
6
12
beta-Carotene
2
12
Aloe Vera
6
11
Curcuminoids
2
11
Diallyl sulfide
6
11
Lactobacillus fermentum
6
11
Lignans
7
11
Lychee
6
11
Medicinal Mushrooms
6
11
Myricetin
6
11
Panax Notoginseng
6
11
Alpha-Carotene
1
10
Astragaloside
7
10
Bamboo
5
10
Burdock
5
10
Capsaicin
5
10
Carvacrol
6
10
Cordyceps sinensis
5
10
Cranberry
5
10
Frankincense
5
10
Lactobacillus paracasei
5
10
Menatetrenone
1
10
Multivitamin
1
10
Nuts
1
10
Nuts: All
1
10
Oleocanthal
1
10
Oolong tea
1
10
Rice Bran
5
10
Rosmarinic acid
5
10
Sesame Seed Oil
1
10
Sesamol
5
10
Tetrahydrocurcumin
6
10
Vitamin K2
1
10
Vitamin K2: Menaquinones (MK-4-14)
1
10
Zeaxanthin
1
10
Allicin
5
9
Antrodia camphorata
5
9
Apple
5
9
Bael
5
9
Bee Venom
5
9
Bitter Melon
5
9
Genipin
5
9
Goji
5
9
Indole-3-Carbinol
5
9
Isoliquiritigenin
5
9
Oleuropein
5
9
Purslane
6
9
Safflower
6
9
Amla Fruit
4
8
Barley
4
8
Bee Pollen
4
8
Beta Sitosterol
4
8
Caffeic Acid
5
8
Carnosic Acid
4
8
Carrot
4
8
Chlorella (Algae)
4
8
Citrus Peel
5
8
Cordyceps Militaris
4
8
Dates
4
8
Ferulic acid
5
8
Gallic Acid
5
8
Garlic: Aged
4
8
Honokiol
5
8
Jujube
4
8
Krill
4
8
Litchi
4
8
Mangosteen
4
8
Noni
4
8
Olive
4
8
Orthosiphon
5
8
Pomegranate Peel
4
8
Poria cocos
5
8
Prickly Pear Cactus
5
8
Propolis: Bee
4
8
Pumpkin Seeds
4
8
Punicalagin
5
8
Rhubarb
4
8
Solanum nigrum (black nightshade)
4
8
Stevia
4
8
Vitexins
4
8
Ashwagandha
4
7
Berbamine
4
7
Beta-Caryophyllene
4
7
Chamomile
4
7
Eriodictyol
4
7
Fig
4
7
Gynostemma
5
7
Kombucha Tea
5
7
Liquiritigenin
4
7
Loquat
4
7
Nettle
4
7
Oleanolic acid
4
7
Oridonin
4
7
Palash
4
7
Rosemaric Acid
5
7
Acacia catechu
3
6
Angelica
3
6
Apple Cider Vinegar
3
6
Astragalus
4
6
Ayurvedic formulation: Liv52
3
6
Baicalein
3
6
Basil
3
6
Berries: All
3
6
Betanin
3
6
Black Raspberry
3
6
Blackberry
4
6
Choline
3
6
Cinnamon
3
6
Coconut Oil
3
6
Coconut Water
3
6
Dragon Fruit
3
6
EPA (Eicosapentaenoic Acid)
3
6
FOS (Fructooligosaccharides)
3
6
Folic Acid
3
6
Hu Zhang (Polygonum cuspidatum)
3
6
Juniper
3
6
Kaempferol
3
6
Marjoram
3
6
Oregano
4
6
Passion Flower
3
6
Phellinus Linteus
4
6
Phosphatidylcholine
3
6
Policosanol
3
6
Pomegranate Seed
3
6
Pumpkin Seed Oil/Meal
3
6
Pycnogenol (Pine Bark)
3
6
Raspberry
3
6
Salvia miltiorrhiza
3
6
Shiitake Mushroom
3
6
Taurine
3
6
Thyme
3
6
Whey
3
6
Yellow Tea
3
6
Zerumbone
3
6
Arctigenin
3
5
Babchi
3
5
Biochanin A
3
5
Cannabinoids
3
5
Chaga Mushroom (Inonotus obliquus)
4
5
Crocetin
3
5
Emodin
3
5
Eugenol
3
5
Fruit: All
3
5
Kudzu
3
5
Lemon Balm
3
5
Mugwort
4
5
Procyanidin B2
3
5
Quince
3
5
Red Cabbage
3
5
Rooibos
3
5
Sage
3
5
Sweet Potato
3
5
Tangeretin
4
5
Thistle
4
5
Tomatidine
3
5
Toona sinensis
3
5
Vitamin E: alpha tocopherol
3
5
Watercress
3
5
Wheat Grass
3
5
Amygdalin (laetrile)
2
4
Anise
2
4
Baccharis trimera
2
4
Beeswax
2
4
Benzyl isothiocyanate
2
4
Bifidobacterium Longum
2
4
Bitter Apple
2
4
Bitter Orange
2
4
Cannabis
2
4
Coffee: Green/Unroasted
2
4
Coriandrum sativum
2
4
Corn: Purple
2
4
Cucurbitacin B
2
4
D-Limonene
2
4
Date Seeds
2
4
Dill
2
4
Diosgenin
3
4
Embelia ribes
2
4
Feverfew
2
4
Flaxseed Oil
2
4
Formononetin
2
4
Gastrodin
2
4
Ginseng (American)
2
4
Gotu Kola
2
4
Guarana
2
4
Henna
2
4
Horehound
2
4
Isothiocyanates
2
4
Kefir
2
4
Kimchi
2
4
Lactobacillus probiotics
2
4
Lemon
2
4
Ligustrazine
2
4
Lingonberry
2
4
Magnolol
2
4
Maitake Mushroom
2
4
Okra
2
4
Oyster Mushroom
2
4
Panax Ginseng
2
4
Patchouli
2
4
Phloretin
3
4
Piceatannol
2
4
Pine Nut
2
4
Potato
2
4
Pumpkin
2
4
Raspberry ketone
2
4
Stigmasterol
2
4
Sweet Cherry
2
4
Syrian rue
2
4
Tamarind
3
4
Tannic Acid
2
4
Verbascoside
2
4
Vitex negundo
2
4
Xanthones
2
4
Yeast
2
4
Agaricus Blazei
2
3
Asparagus
2
3
Barberry
2
3
Celery seed
2
3
Chrysanthemum Indicum
2
3
Clove
2
3
Cucumber
2
3
Curcumol
2
3
Dong Quai
2
3
Guava
2
3
Huperzine
2
3
Lactobacillus reuteri
2
3
Lion's Mane (Hericium Erinaceus)
2
3
Motherwort
2
3
Mung Bean
2
3
Nicotinamide adenine dinucleotide (NADH)
2
3
Nutmeg
2
3
Phyllanthus urinaria
2
3
Pine Bark Extract
2
3
Seaweed
2
3
Terminalia chebula
2
3
Thymol
2
3
Water: Deep Sea
2
3
2-Methoxyestradiol
1
2
6-Shogaol
1
2
Acai
1
2
Acerola
1
2
Adlay
1
2
Ajwain
1
2
Algae
1
2
Almond
1
2
Amygdalin
1
2
Andrographis
1
2
Apocynin
1
2
Apples
1
2
Apricot
1
2
Apricot Kernel
1
2
Arginine
1
2
Artemisinin
1
2
Artesunate
1
2
Avocado
1
2
Bacopa
1
2
Banana
1
2
Banana Peel
1
2
Banana Stem
1
2
Bay leaf
1
2
Betaine
1
2
Bifidobacterium Lactis
1
2
Bisdemethoxycurcumin
1
2
Black Tea Theaflavins
1
2
Boron
1
2
Broccoli Sprouts
1
2
Bromelain
1
2
Brown Rice
1
2
Buckwheat
1
2
Butterbur
1
2
Butyrate
1
2
Caffeine
1
2
Calcium
1
2
Cardamonin
1
2
Carnosine
1
2
Cashew
1
2
Celastrol
1
2
Celery Oil
1
2
Celosia cristata (cockscomb)
1
2
Centella asiatica
1
2
Cherry: All Varieties
1
2
Chickpea
1
2
Cissus quadrangularis
1
2
Citric Acid
1
2
Cloudberry
1
2
Cocoa Butter
1
2
Copper
1
2
Coptidis rhizoma
1
2
Crowberry
1
2
Cucurbitacin E
1
2
Cumin
1
2
Cysteine (see N-Acetylcysteine)
1
2
Dibenzoylmethane (DBM)
1
2
Dogwood
1
2
Earthworms
1
2
Echinacea
1
2
Eggplant
1
2
Elderberry
1
2
False Black Pepper
1
2
Feijoa
1
2
Fennel
1
2
Fish Oil
1
2
Flowers
1
2
Galacto-oligosaccharides
1
2
Galbanic Acid
1
2
Gamma-Oryzanol
1
2
Gardenia
1
2
Geranium
1
2
Ginseng (Siberian)
1
2
Glycyrrhiza uralensis
1
2
Gold (nanoparticles)
1
2
Goldenseal
1
2
Grapefruit
1
2
Graviola
1
2
Green Coffee Bean
1
2
Harmine
1
2
Hazelnut
1
2
Helenalin
1
2
Hibiscus rosa-sinensis
1
2
Histidine
1
2
Homeopathic Medicine: All
1
2
Homeopathic Medicine: Lycopodium
1
2
Honeydew (melon)
1
2
Hops
1
2
Horse Chestnut
1
2
Humic Acid
1
2
Hydrangea
2
2
Indian Gooseberry
1
2
Indian Mulberry
2
2
Isoflavones
1
2
Isoquercitrin
1
2
Kiwifruit
1
2
Lactobacillus casei: Shirota
1
2
Lactobacillus rhamnosus
1
2
Lactobacillus salivarius
1
2
Lactoferrin
1
2
Lavender
2
2
Lecithin
1
2
Linden (Tilia)
1
2
Lobelia
1
2
Long Pepper
1
2
Loquat Seeds
1
2
MSM (Methylsulfonylmethane)
1
2
Maca
1
2
Magnesium Sulfate
1
2
Mango
1
2
Manuka Honey
1
2
Maple Syrup
1
2
Mastic gum
1
2
Medium Chain Triglycerides
1
2
Mint
1
2
Miso
1
2
Modified Arabinoxylan Rice Bran (MGN-3)
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Myrica rubra
1
2
Myrrh
1
2
Oak
1
2
Oats
1
2
Oleic acid
1
2
Oligosaccharides
1
2
Olives
1
2
Orange
1
2
P-Coumaric Acid
1
2
Palmitoylethanolamide
1
2
Papaya
1
2
Papaya: Fermented
1
2
Parsley
1
2
Parthenolide
1
2
Pear
1
2
Pecan
1
2
Pectin
1
2
Peppermint
1
2
Phenethyl isothiocyanate
1
2
Phospholipids
1
2
Phyllanthus emblica
1
2
Pine Needle
1
2
Piper cubeba (Cubeb)
1
2
Piperlongumine
1
2
Plant Stem Cells
1
2
Plantago
1
2
Plantago asiatica
1
2
Plantago major
1
2
Platycodon grandiflorum
1
2
Pleurotus nebrodensis
1
2
Pomelo
1
2
Proanthocyanidins
1
2
Propolis: Brazillian
1
2
Protein Supplement
1
2
Prunella vulgaris
1
2
Pterocarpus marsupium
1
2
Pueraria mirifica
1
2
Purple Carrots
1
2
Raisins
1
2
Rambutan
1
2
Red Sage
1
2
Red Wine
1
2
Rice
1
2
Rice: Brown
1
2
Rice: Parboiled
1
2
Rose Hips
1
2
SAMe (S-adenosylmethionine)
1
2
Safranal
1
2
Saikosaponin
1
2
Sesame Seeds
1
2
Sesamin
1
2
Sessile Joyweed
1
2
Shallot
1
2
Skullcap: Chinese
1
2
Soursop
1
2
Soy
1
2
Soybean: Black
1
2
Spearmint
1
2
Spermidine
1
2
Spinach
1
2
St. Johns Wort
1
2
Star Fruit
1
2
Stilbenes
1
2
Taro
1
2
Theanine
1
2
Tomato
1
2
Tribulus
1
2
Tyrosine
1
2
Vanillin
1
2
Virgin Coconut Oil
1
2
Vitamin B-3 (Niacin)
1
2
Vitamin E: Gamma-tocotrienol
1
2
Water: Deuterium Depleted
1
2
Water: Electrolyzed Reduced
1
2
White Clover
1
2
Wogonin
1
2
Wormwood
2
2
Yarrow
1
2
Yellow Sweet Clover (Melilotus officinalis)
1
2
Agrimony
1
1
B-Carotene
1
1
Beta-Elemene
1
1
Caraway
1
1
Cocoa
1
1
Coriandor
1
1
Crimini Mushroom
1
1
Cyanidin 3-glucoside
1
1
Cyperus longus
1
1
Delphinidin
1
1
Glucosamine
1
1
Haritaki (Terminalia chebula)
1
1
Lupeol
1
1
Methionine
1
1
Mushrooms: All
1
1
Muskmelon
1
1
Mustard: Field/Turnip
1
1
Persimmon
1
1
Prebiotics
1
1
Quinoa
1
1
Rice: Black
1
1
S-Adenosylmethionine (SAMe)
1
1
Tarragon
1
1
Vitamin A
1
1
Water Mint
1
1
White Mulberry
1
1
neohesperidin
1
1
Research Articles
2264
Cumulative Knowledge Score
3663
Overall Research Rating
EXCELLENT
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View the Evidence:
2794 Abstracts with Hepatoprotective Research
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[+]
Acupuncture may be effective and safe for treatment of NAFLD.
Sep 23, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2021 Sep 24 ;100(38):e27050. PMID:
34559098
Article Published Date
: Sep 23, 2021
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Hepatoprotective
[+]
Coffee consumption can significantly reduce the risk for hepatic fibrosis and cirrhosis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015;10(11):e0142457. Epub 2015 Nov 10. PMID:
26556483
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Coffee
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Coffee consumption could lower the risks of liver cancers, liver diseases and liver cirrhosis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2016 ;9:4369-75. Epub 2016 Jul 19. PMID:
27499631
Article Published Date
: Dec 31, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Coffee
Diseases
:
Liver Cancer
,
Liver Cirrhosis
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Hepatoprotective
[+]
Effect of Nigella sativa in the treatment of nonalcoholic fatty liver disease/
Mar 15, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Mar 16. Epub 2021 Mar 16. PMID:
33728708
Article Published Date
: Mar 15, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Effect of saffron supplementation on liver enzymes: A systematic review and meta-analysis of randomized controlled trials.
Oct 11, 2021
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2021 Oct 12 ;15(6):102311. Epub 2021 Oct 12. PMID:
34678576
Article Published Date
: Oct 11, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Saffron
Diseases
:
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Effects of garlic supplementation on liver enzymes: A systematic review and meta-analysis of randomized controlled trials.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Aug ;34(8):1947-1955. Epub 2020 Mar 5. PMID:
32135032
Article Published Date
: Jul 31, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Garlic
Diseases
:
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Efficacy and safety of total glucosides of paeony combined with methotrexate and leflunomide for active rheumatoid arthritis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2019 ;13:1969-1984. Epub 2019 Jun 17. PMID:
31354242
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Peony
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
Additional Keywords
:
Natural Substance/Drug Synergy
Problem Substances
:
Methotrexate
[+]
Evaluation of astragaloside IV in hepatic fibrosis: A meta-analysis.
Apr 01, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2021 Apr 2 ;100(13):e25105. PMID:
33787592
Article Published Date
: Apr 01, 2021
Study Type
: Meta Analysis
Additional Links
Substances
:
Astragaloside
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Green tea intake reduces the risk of liver disease.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015;8(6):8339-8346. Epub 2015 Jun 15. PMID:
26309486
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Green Tea
Diseases
:
Liver Cancer: Prevention
,
Liver Cirrhosis
,
Liver Diseases
,
Liver Steatosis
Pharmacological Actions
:
Anticarcinogenic Agents
,
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Impact of silymarin in individuals with nonalcoholic fatty liver disease.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2021 03 ;83:111092. Epub 2020 Nov 25. PMID:
33418491
Article Published Date
: Dec 31, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Silymarin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Med-Diet is a beneficial pharmaconutritional therapy in patients with NAFLD.
Jun 18, 2021
Click here to read the entire abstract
Pubmed Data
: Semin Liver Dis. 2021 Jun 19. Epub 2021 Jun 19. PMID:
34147036
Article Published Date
: Jun 18, 2021
Study Type
: Meta Analysis
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Hepatoprotective
[+]
Physical activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD.
May 03, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2016 May 4. Epub 2016 May 4. PMID:
27155553
Article Published Date
: May 03, 2016
Study Type
: Meta Analysis
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Risk Reduction
[+]
Polyunsaturated fatty acids supplementation can improve liver steatosis and liver functions.
Dec 22, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2016 Dec 23. Epub 2016 Dec 23. PMID:
28040302
Article Published Date
: Dec 22, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Hepatic Steatosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Prophylactic therapy of milk thistle on anti-tuberculosis drug-induced liver injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Can J Gastroenterol Hepatol. 2019 ;2019:3192351. Epub 2019 Jan 10. PMID:
30733935
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Milk Thistle
Diseases
:
Chemically-Induced Liver Damage
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Saffron supplementation can reduce ALT serum concentrations without significant effects on other liver function indicators.
Mar 15, 2021
Click here to read the entire abstract
Pubmed Data
: Crit Rev Food Sci Nutr. 2021 Mar 16:1-13. Epub 2021 Mar 16. PMID:
33724127
Article Published Date
: Mar 15, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Saffron
Diseases
:
Liver Damage
Pharmacological Actions
:
Enzyme Inhibitors
,
Hepatoprotective
[+]
Studies on coffee and NAFLD suggest that coffee consumption could have a protective role on fibrosis.
Mar 29, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2016 Mar 30. Epub 2016 Mar 30. PMID:
27060021
Article Published Date
: Mar 29, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coffee
,
Tea: Black
,
Tea: Green
Diseases
:
Metabolic Diseases
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Synergistic and hepatoprotective effect of total glucosides of paeony on ankylosing spondylitis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:231. Epub 2019 Mar 19. PMID:
30941036
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Peony
Diseases
:
Spondylitis: Ankylosing
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
Tanshinone IIA can effectively improve liver fibrosis and liver function.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:7514046. Epub 2019 Dec 13. PMID:
31915451
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
The safety and efficacy of Momordica charantia L. in animal models of type 2 diabetes mellitus.
Jan 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytother Res. 2021 Feb ;35(2):637-656. Epub 2020 Sep 14. PMID:
32929814
Article Published Date
: Jan 31, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Bitter Melon
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
,
Renoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
These results found a significantly decreased risk of NAFLD among coffee drinkers and significantly decreased risk of liver fibrosis.
Nov 06, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2016 Nov 7. Epub 2016 Aug 7. PMID:
27824642
Article Published Date
: Nov 06, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coffee
Diseases
:
Liver Fibrosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.
Apr 30, 2020
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2020 May ;99(19):e20296. PMID:
32384521
Article Published Date
: Apr 30, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Vitamin D
Diseases
:
Liver Disease
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Total glucosides of paeony adjuvant therapy might alleviate the incidence of hepatic adverse effect and leukopenia for the rheumatoid arthritis treatment.
Mar 25, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2021 Mar 26 ;21(1):102. Epub 2021 Mar 26. PMID:
33771151
Article Published Date
: Mar 25, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Peony
Diseases
:
Leukopenia
,
Rheumatoid Arthritis
Pharmacological Actions
:
Hepatoprotective
[+]
Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2015 Jul-Aug;31(7-8):923-30. Epub 2014 Dec 24. PMID:
26059365
Article Published Date
: Jun 30, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin E
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis.
Jan 21, 2019
Click here to read the entire abstract
Pubmed Data
: JAMA. 2019 01 22 ;321(3):256-265. PMID:
30667502
Article Published Date
: Jan 21, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Dietary Modification
[+]
A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients.
Apr 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2015 May ;94(20):e758. PMID:
25997043
Article Published Date
: Apr 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
,
Black Currant
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
A multivitamin and phospholipids complex protects the hepatic cells from androgenic-anabolic-steroids-induced toxicity.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Clin Toxicol (Phila). 2008 Jan;46(1):57-66. PMID:
17852158
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Multivitamin
Diseases
:
Androgen-Induced Diseases
,
Steroid-Induced Toxicity: Androgenic-Anabolic steroids
Pharmacological Actions
:
Hepatoprotective
[+]
A probiotic yogurt demonstrates a significant rate of minimal hepatic encephalopathy reversal.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 2008 Jul;103(7):1707-15. PMID:
18691193
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
Diseases
:
Hepatic Encephalopathy
,
Liver Cirrhosis
,
Liver Cirrhosis: Alcoholic
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Disease Reversal
[+]
A vitamin K2 preparation inhibits the development of liver cancer in patients with type C cirrhosis.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Hepatogastroenterology. 2010 Sep-Oct;57(102-103):1264-7. PMID:
21410069
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Menatetrenone
,
Vitamin K2
,
Vitamin K2: Menaquinones (MK-4-14)
Diseases
:
Liver Cancer
,
Liver Cirrhosis
Pharmacological Actions
:
Anticarcinogenic Agents
,
Hepatoprotective
[+]
Acetylcysteine for the treatment of suspected remdesivir-associated acute liver Failure in COVID-19.
Oct 01, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacotherapy. 2020 Oct 2. Epub 2020 Oct 2. PMID:
33006138
Article Published Date
: Oct 01, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
AGM possibly improves insulin sensitivity and β-cell function and reduces liver damage and inflammation in prediabetic adults.
Jul 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2021 Jul 5 ;10(7). Epub 2021 Jul 5. PMID:
34359426
Article Published Date
: Jul 04, 2021
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
,
Ginseng
,
Nattokinase
,
Shiitake Mushroom
Diseases
:
Prediabetes
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Almond protects the liver in coronary artery disease.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2021 Mar ;71(3):791-795. PMID:
34057922
Article Published Date
: Feb 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Almond
Diseases
:
Coronary Artery Disease
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.
Oct 24, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Oct 25 ;11(11). Epub 2019 Oct 25. PMID:
31731527
Article Published Date
: Oct 24, 2019
Study Type
: Human Study
Additional Links
Substances
:
Chlorogenic Acid
,
Luteolin
Diseases
:
Cardiovascular Diseases
,
Metabolic Syndrome X
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Cardioprotective
,
Hepatoprotective
[+]
An improved diet is particularly important for individuals with a high genetic risk for NAFLD.
Mar 27, 2018
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2018 Mar 28. Epub 2018 Mar 28. PMID:
29604292
Article Published Date
: Mar 27, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.
Oct 11, 2020
Click here to read the entire abstract
Pubmed Data
: Dig Liver Dis. 2020 Oct 12. Epub 2020 Oct 12. PMID:
33060043
Article Published Date
: Oct 11, 2020
Study Type
: Human Study
Additional Links
Substances
:
Hydroxytyrosol
,
Vitamin E
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antioxidative effects of silymarin on the reduction of liver complications of fingolimod in patients with relapsing-remitting multiple sclerosis.
May 01, 2021
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2021 May 2:e22800. Epub 2021 May 2. PMID:
33934443
Article Published Date
: May 01, 2021
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Liver Damage
,
Multiple Sclerosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Artichoke leaf extracts have benefits in the management of NASH.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Hepatol. 2016 ;2016:4030476. Epub 2016 May 11. PMID:
27293900
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Artichoke
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Association between serum vitamin D level and immune imbalance in advanced schistosomiasis patients with liver fibrosis.
Feb 03, 2021
Click here to read the entire abstract
Pubmed Data
: Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2021 Feb 4 ;33(1):22-27. PMID:
33660470
Article Published Date
: Feb 03, 2021
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
,
Schistosomiasis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Immunomodulatory
[+]
Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.
Feb 02, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Feb 3. Epub 2020 Feb 3. PMID:
32017253
Article Published Date
: Feb 02, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cirrhosis
Pharmacological Actions
:
Hepatoprotective
[+]
Beneficial effects of ketogenic diet in women with polycystic ovary syndrome and liver dysfunction who are obese.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: J Obstet Gynaecol Res. 2021 Mar ;47(3):1145-1152. Epub 2021 Jan 18. PMID:
33462940
Article Published Date
: Feb 28, 2021
Study Type
: Human Study
Additional Links
Diseases
:
Liver Damage
,
Obesity
,
Polycystic Ovary Syndrome
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 2018 Dec ;109(6):418-428. Epub 2018 Sep 13. PMID:
30221912
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Probiotics
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Beneficial effects of silybin treatment after viral eradication in patients with HCV.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:824879. Epub 2022 Feb 2. PMID:
35185575
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Hepatitis C
,
Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Black cumin seeds decreased Methotrexate hepatotoxicity and improved survival in children with ALL
Mar 19, 2015
Click here to read the entire abstract
Pubmed Data
: Infect Disord Drug Targets. 2015 Mar 20. Epub 2015 Mar 20. PMID:
25809628
Article Published Date
: Mar 19, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acute lymphoblastic leukemia (ALL)
,
Drug-Induced Toxicity: Methotrexate
Pharmacological Actions
:
Chemotherapeutic
,
Hepatoprotective
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Chia-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.
May 18, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2020 May 19 ;19(1):96. Epub 2020 May 19. PMID:
32430018
Article Published Date
: May 18, 2020
Study Type
: Human Study
Additional Links
Substances
:
Chia
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea
Jan 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Jan 31. Epub 2018 Jan 31. PMID:
29384173
Article Published Date
: Jan 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Oolong tea
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Hypolipidemic
[+]
Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.
Mar 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2014 Apr ;5(4):734-9. Epub 2014 Feb 19. PMID:
24549255
Article Published Date
: Mar 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Cranberry supplementation had a positive effect on some lipid profiles, insulin resistance, and hepatic steatosis in patients with NAFLD.
Nov 18, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2021 Nov 19 ;21(1):283. Epub 2021 Nov 19. PMID:
34798892
Article Published Date
: Nov 18, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cranberry
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anticholesteremic Agents
,
Hepatoprotective
,
Hypolipidemic
[+]
Curcuma longa (turmeric) and tinospora cordifolia (guduchi) prevents antibiotic-induced liver damage in patients with tubercolosis.
Aug 14, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Aug 14;14(30):4753-62.PMID:
18720535
Article Published Date
: Aug 14, 2008
Study Type
: Human Study
Additional Links
Substances
:
Guduchi
,
Turmeric
Diseases
:
Pulmonary Tubercolosis
,
Tubercolosis: Latent
,
Tuberculosis
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Antitubercular Agents
,
Hepatoprotective
Additional Keywords
:
Ethambutol
,
Isoniazid
,
Pyrazinamide
,
Rifampicin
[+]
Curcumin alleviates ethanol-induced oxidative damage in liver cells.
Jan 18, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID:
20080166
Article Published Date
: Jan 18, 2010
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin prevented the development of immunological alterations in NAFLD.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0172900. Epub 2017 Mar 3. PMID:
28257515
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Mar ;49:102322. Epub 2020 Jan 21. PMID:
32147075
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcuminoids
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin-galactomannoside complex offered significant hepatoprotective effects to attenuate alcohol induced alterations to hepatic function markers.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2018 ;2018:9159281. Epub 2018 Sep 23. PMID:
30345312
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Aug ;52:102494. Epub 2020 Jun 23. PMID:
32951743
Article Published Date
: Jul 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin E: delta-tocopherol
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
DHA supplementation improves liver steatosis in children with NAFLD.
Oct 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2013 Nov ;23(11):1066-70. Epub 2012 Dec 7. PMID:
23220074
Article Published Date
: Oct 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Dietary vitamin C intake is associated with improved liver function and glucose metabolism in Chinese adults.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Nutr. 2021 ;8:779912. Epub 2022 Jan 31. PMID:
35174195
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.
Sep 03, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMJ Open. 2019 Sep 4 ;9(9):e028961. Epub 2019 Sep 4. PMID:
31488477
Article Published Date
: Sep 03, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nuts: All
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity.
Mar 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2017 Mar 15. Epub 2017 Mar 15. PMID:
28294174
Article Published Date
: Mar 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease.
Jan 27, 2020
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2020 08 28 ;124(4):450-456. Epub 2020 Apr 21. PMID:
32312333
Article Published Date
: Jan 27, 2020
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Effect of Korea red ginseng on nonalcoholic fatty liver disease.
Feb 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2021 Mar ;45(2):316-324. Epub 2020 Jul 16. PMID:
33841012
Article Published Date
: Feb 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Effect of L-carnitine on health-related quality of life in patients with liver cirrhosis.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Rep. 2020 Dec ;13(6):65. Epub 2020 Oct 20. PMID:
33149909
Article Published Date
: Nov 30, 2020
Study Type
: Human Study
Additional Links
Substances
:
L-Carnitine
Diseases
:
Liver Cirrhosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury.
Jan 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Clin Nutr. 2021 Jan 29. Epub 2021 Jan 29. PMID:
33514869
Article Published Date
: Jan 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus casei
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Gastrointestinal Agents
,
Hepatoprotective
,
Hypolipidemic
[+]
Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 May ;32(3 Special):1343-1348. PMID:
31551213
Article Published Date
: Apr 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Effects of curcumin supplementation on vitamin D levels in women with premenstrual syndrome and dysmenorrhea.
Jan 21, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2022 Jan 22 ;22(1):19. Epub 2022 Jan 22. PMID:
35065636
Article Published Date
: Jan 21, 2022
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Vitamin D
Diseases
:
Dysmenorrhea
Pharmacological Actions
:
Hepatoprotective
[+]
Effects of oral vitamin C supplementation on liver health and associated parameters.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Nutr. 2021 ;8:745609. Epub 2021 Sep 14. PMID:
34595203
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
[+]
Efficacy of diammonium glycyrrhizinate combined with vitamin C for treating hospitalized COVID-19 patients.
Jul 25, 2021
Click here to read the entire abstract
Pubmed Data
: QJM. 2021 Jul 26. Epub 2021 Jul 26. PMID:
34314507
Article Published Date
: Jul 25, 2021
Study Type
: Human Study
Additional Links
Substances
:
Licorice
,
Vitamin C
Diseases
:
Coronavirus Infection
Pharmacological Actions
:
Antiviral Agents
,
Cardioprotective
,
Hepatoprotective
[+]
Efficacy of zinc supplement in minimal hepatic encephalopathy.
Aug 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2021 Sep 1 ;22(9):2879-2887. Epub 2021 Sep 1. PMID:
34582657
Article Published Date
: Aug 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Zinc
Diseases
:
Hepatic Encephalopathy
Pharmacological Actions
:
Hepatoprotective
[+]
Electroacupuncture and aerobic interval training exercise are potent modalities that improve liver functions in people with Nonalcoholic fatty liver disease.
Oct 28, 2019
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2019 Oct 29. Epub 2019 Oct 29. PMID:
31657614
Article Published Date
: Oct 28, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Electroacupuncture
,
Exercise: Aerobic
Pharmacological Actions
:
Hepatoprotective
[+]
Extra virgin olive oil with a high oleocanthal concentration had beneficial effects on metabolic parameters in MetS subjects.
Oct 01, 2020
Click here to read the entire abstract
Pubmed Data
: Metabolites. 2020 Oct 2 ;10(10). Epub 2020 Oct 2. PMID:
33023123
Article Published Date
: Oct 01, 2020
Study Type
: Human Study
Additional Links
Substances
:
Oleocanthal
,
Olive Oil
Diseases
:
Hepatic Steatosis
,
Inflammation
,
Metabolic Syndrome X
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Hepatoprotective
,
Hypolipidemic
[+]
Fenugreek seed intake has some beneficial effects on FPG, SBP, and some liver and kidney function tests in patients with T2DM.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Mar ;49:102315. Epub 2020 Feb 1. PMID:
32147060
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Fenugreek
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
,
Renoprotective
[+]
Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2017 Aug ;56(5):1993-2002. Epub 2016 Oct 14. PMID:
27743130
Article Published Date
: Jul 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Garlic
Diseases
:
Liver Disease
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2013 ;13:58. Epub 2013 Mar 8. PMID:
23497020
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Turmeric: Fermented
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.
Jan 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2020 Jan 29:1-24. Epub 2020 Jan 29. PMID:
31992372
Article Published Date
: Jan 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID:
26983396
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Insulin Resistance
,
Liver Fibrosis
,
Liver Steatosis
,
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Integrative Medicine
,
Lifestyle Changes: Positive
Pharmacological Actions
:
Anti-Fibrotic
,
Enzyme Inhibitors
,
Hepatoprotective
Additional Keywords
:
Significant Treatment Outcome
[+]
Fructose restriction decreased liver fat, visceral fat, and de novo lipogenesis, and improved insulin kinetics in children with obesity.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2017 Jun 1. Epub 2017 Jun 1. PMID:
28579536
Article Published Date
: May 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Obesity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Fructose
[+]
Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.
Mar 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2021 Mar 12 ;19(3). Epub 2021 Mar 12. PMID:
33809062
Article Published Date
: Mar 11, 2021
Study Type
: Human Study
Additional Links
Substances
:
Fucoidan
,
Fucoxanthin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
[+]
Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adv Biomed Res. 2016 ;5:2. Epub 2016 Jan 27. PMID:
26955623
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Anti-Obesity Agents
[+]
Garlic powder supplementation improved risk factors of NAFLD.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Jun ;51:102428. Epub 2020 May 11. PMID:
32507439
Article Published Date
: May 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Insulin Resistance
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
[+]
Green tea extract therapy resulted in significant improvement in metabolic, chemical, inflammatory and radiological parameters of NAFLD patients.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pak J Med Sci. 2017 Jul-Aug;33(4):931-936. PMID:
29067068
Article Published Date
: Jun 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Jul 1. Epub 2019 Jul 1. PMID:
31264313
Article Published Date
: Jun 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.
Apr 01, 2018
Click here to read the entire abstract
Pubmed Data
: Public Health Nutr. 2018 Apr 2:1-8. Epub 2018 Apr 2. PMID:
29607802
Article Published Date
: Apr 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Prediabetes
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Higher coffee consumption was associated with lower risk of elevated aminotransferase concentration in Korean adults.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asia Pac J Clin Nutr. 2016 Dec ;25(4):767-775. PMID:
27702720
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Liver Disease
Pharmacological Actions
:
Enzyme Inhibitors
,
Hepatoprotective
[+]
Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.
May 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 May 17 ;11(5). Epub 2019 May 17. PMID:
31108934
Article Published Date
: May 16, 2019
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Carotene
,
beta-Carotene
,
Carotenoids
,
Cryptoxanthin
,
Lutein
,
Zeaxanthin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Hijamat resulted in a relative improvement in fatty liver severity and improved HOMA-IR and liver enzymes.
Jan 08, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Med Sci. 2020 04 9 ;50(2):354-359. Epub 2020 Apr 9. PMID:
31999405
Article Published Date
: Jan 08, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Cupping
Pharmacological Actions
:
Hepatoprotective
[+]
Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease.
Apr 10, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Res Hepatol Gastroenterol. 2019 Apr 11. Epub 2019 Apr 11. PMID:
30982748
Article Published Date
: Apr 10, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Hydrogen-rich water significantly attenuates oxidative stress in chronic hepatitis B patients.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Transl Sci. 2013 Oct ;6(5):372-5. Epub 2013 Jun 13. PMID:
24127924
Article Published Date
: Sep 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Hepatitis B
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Intake of nuts and seeds is associated with a lower prevalence of nonalcoholic fatty liver disease.
Sep 14, 2021
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2021 Sep 15. Epub 2021 Sep 15. PMID:
34522969
Article Published Date
: Sep 14, 2021
Study Type
: Human Study
Additional Links
Substances
:
Nuts
,
Seeds
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Ketogenic, hypocaloric diet improves nonalcoholic steatohepatitis.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Transl Int Med. 2020 Mar ;8(1):26-31. Epub 2020 May 9. PMID:
32435609
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Antihypertensive Agents
,
Hepatoprotective
,
Hypolipidemic
[+]
Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2016 Dec ;22(12):964-969. Epub 2016 Sep 7. PMID:
27603149
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Hepatitis B
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Low 25(OH)vitamin D levels are associated with the presence of NAFLD independently from metabolic syndrome, diabetes and insulin-resistance profile.
Jul 11, 2011
Click here to read the entire abstract
Pubmed Data
: BMC Med. 2011 Jul 12 ;9:85. Epub 2011 Jul 12. PMID:
21749681
Article Published Date
: Jul 11, 2011
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Vitamin D Deficiency
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Factors
[+]
Maintenance of high cardiorespiratory fitness and stability of body weight are critical public health considerations for the treatment of NAFLD.
Jul 20, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Obes (Lond). 2016 Jul 21. Epub 2016 Jul 21. PMID:
27439593
Article Published Date
: Jul 20, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Hepatoprotective
[+]
n-3 PUFA treatment is safe and efficacious in obese children with NAFLD and can improve ultrasonographic findings and the elevated transaminase levels.
Jun 04, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Res Pediatr Endocrinol. 2015 Jun 5 ;7(2):121-7. PMID:
26316434
Article Published Date
: Jun 04, 2015
Study Type
: Human Study
Additional Links
Substances
:
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Hepatoprotective
[+]
N-acetyl cysteine may have a protective effect against reperfusion injury in liver transplant recipients.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Transplant Proc. 2008 Nov;40(9):2978-80. PMID:
19010165
Article Published Date
: Nov 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Organ Transplantation: Liver
Pharmacological Actions
:
Hepatoprotective
[+]
N-acetylcysteine supplementation for the prevention of postoperative liver dysfunction after on-pump cardiac surgery.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: Turk J Anaesthesiol Reanim. 2021 Dec ;49(6):460-469. PMID:
35110025
Article Published Date
: Nov 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Cardiac Surgery
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
N. sativa seed oil seems to be safe and improve liver steatosis and injury and blood levels of triglycerides, LDL-C and HDL-C in the NAFLD patients.
Apr 23, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Apr 24 ;234:106-111. Epub 2019 Jan 11. PMID:
30639231
Article Published Date
: Apr 23, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
NAC has a therapeutic effect on hepatotoxicity in children being treated with chemotherapeutic agents.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: Ir J Med Sci. 2020 Apr 1. Epub 2020 Apr 1. PMID:
32239424
Article Published Date
: Mar 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
NAC should be considered in management of anti-tuberculosis drug induced liver injury.
Aug 25, 2020
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2020 Aug 26. Epub 2020 Aug 26. PMID:
32845997
Article Published Date
: Aug 25, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Naringenin supplementation improves lipid profile, severity of hepatic steatosis and probability of liver fibrosis in overweight/obese patients with NAFLD.
Sep 12, 2021
Click here to read the entire abstract
Pubmed Data
: Int J Clin Pract. 2021 Sep 13:e14852. Epub 2021 Sep 13. PMID:
34516703
Article Published Date
: Sep 12, 2021
Study Type
: Human Study
Additional Links
Substances
:
Naringenin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Nigella sativa seed oil supplements may decrease the liver enzymes and lipid profiles in the patients with NAFLD.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Diabetes Metab Disord. 2019 Dec ;18(2):453-459. Epub 2019 Sep 11. PMID:
31890671
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Nut consumption might exert beneficial effects on the prevalence of NAFLD in males.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2020 ;15(12):e0244514. Epub 2020 Dec 31. PMID:
33382757
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nuts
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
Oral silymarin formulation efficacy in management of AC-T protocol induced hepatotoxicity in breast cancer patients.
Apr 15, 2021
Click here to read the entire abstract
Pubmed Data
: J Oncol Pharm Pract. 2021 Apr 16:10781552211006182. Epub 2021 Apr 16. PMID:
33861657
Article Published Date
: Apr 15, 2021
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Chemotherapy-Induced Toxicity: Paclitaxel
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Chemotherapeutic
,
Hepatoprotective
[+]
Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pak J Med Sci. 2020 Mar-Apr;36(3):445-450. PMID:
32292450
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Hepatitis C
,
Liver Damage
,
Vitamin D Deficiency
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Increased Risk
[+]
Probiotic compounds can be effective in improving pediatric NAFLD.
Oct 12, 2016
Click here to read the entire abstract
Pubmed Data
: J Pediatr Gastroenterol Nutr. 2016 Oct 13. Epub 2016 Oct 13. PMID:
27753706
Article Published Date
: Oct 12, 2016
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Clin Oncol. 2017 Nov ;7(5):891-896. Epub 2017 Sep 1. PMID:
29142752
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Colorectal Cancer
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Mar ;35(3):1669-1679. Epub 2020 Nov 9. PMID:
33166032
Article Published Date
: Feb 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Results of this clinical trial suggest that short-term treatment with curcumin plus piperine administration improves NAFLD severity.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Adv Exp Med Biol. 2021 ;1328:11-19. PMID:
34981468
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Piperidines
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Rosa damascena meaningfully improves liver function in NAFLD.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:6628911. Epub 2021 Aug 12. PMID:
34422077
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Rose
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Royal jelly might have antiatherogenic property by improving vascular endothelial function.
Sep 27, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Atheroscler Thromb. 2021 Sep 28. Epub 2021 Sep 28. PMID:
34588374
Article Published Date
: Sep 27, 2021
Study Type
: Human Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Atherosclerosis
,
Endothelial Damage
Pharmacological Actions
:
Anti-atherogenic
,
Hepatoprotective
[+]
Short-term supplementation with Curcumin led to an improvement in different features of NAFLD.
Jun 07, 2016
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2016 Jun 8. Epub 2016 Jun 8. PMID:
27270872
Article Published Date
: Jun 07, 2016
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Significant Treatment Outcome
[+]
Short-term vitamin E treatment significantly improves abnormal liver enzyme levels in NAFLD patients with metabolic syndrome.
Nov 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Mol Hepatol. 2015 Dec ;21(4):379-86. Epub 2015 Dec 24. PMID:
26770927
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Significant immunomodulatory and hepatoprotective impacts of Silymarin in MS patients.
Apr 28, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Apr 29 ;97:107715. Epub 2021 Apr 29. PMID:
33933848
Article Published Date
: Apr 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Immunomodulatory
,
Immunomodulatory: Th17 downregulation
,
Interleukin-10 upregulation
[+]
Silibinin could be beneficial in preventing drug-induced liver injury in tuberculosis treatments.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(3):4320-7. Epub 2015 Mar 15. PMID:
26064348
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Silymarin has an efficacy to prevent liver injury from standard combined antituberculosis drugs without significant adverse effects.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):334. Epub 2015 Sep 23. PMID:
26400476
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Interferon Cytokine Res. 2017 Nov ;37(11):480-487. PMID:
29135373
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Silymarin
Diseases
:
Hepatitis C
,
Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Supplementation at a high dosage of 6 g daily in NAFLD patients has strong and multiple beneficial metabolic effects and improves their health-related quality of life.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Gastroenterol. 2014 ;27(4):387-394. PMID:
25331487
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Spirulina
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Quality of Life: Poor
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Significant Treatment Outcome
[+]
Supplementation with sulforaphane rich broccoli sprout extract could improve liver function through reduction of oxidative stress.
Nov 20, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2015 Nov 21 ;21(43):12457-67. PMID:
26604653
Article Published Date
: Nov 20, 2015
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Fatty Liver
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
The association between N-acetylcysteine treatment and hepatic healing in patients with non-acetaminophen-induced liver injury.
Jan 31, 2022
Click here to read the entire abstract
Pubmed Data
: Arch Pediatr. 2022 Feb ;29(2):140-144. Epub 2022 Jan 14. PMID:
35039188
Article Published Date
: Jan 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
The effect of acetyl-L-carnitine, alpha-lipoic acid, and coenzyme Q10 combination in preventing anti-tuberculosis drug-induced hepatotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Pharm Res. 2021 ;20(3):431-440. PMID:
34903999
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
,
Coenzyme Q10
,
L-Carnitine
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
The effect of daily consumption of probiotic yogurt on liver enzymes, steatosis and fibrosis in patients with nonalcoholic fatty liver disease.
Mar 06, 2022
Click here to read the entire abstract
Pubmed Data
: BMC Gastroenterol. 2022 Mar 7 ;22(1):102. Epub 2022 Mar 7. PMID:
35255811
Article Published Date
: Mar 06, 2022
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
The efficacy of Plantago major seed on liver enzymes in nonalcoholic fatty liver disease.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:6693887. Epub 2021 Mar 27. PMID:
33854559
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Plantago
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
The increased amount of coffee consumption lowers the incidence of fatty liver disease in Korean men.
Jun 01, 2020
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2020 Jun 2. Epub 2020 Jun 2. PMID:
32631703
Article Published Date
: Jun 01, 2020
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Risk Reduction
[+]
The present intervention demonstrated the antioxidation, anti-aging and hepatoprotective nature of Ganoderma lucidum.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):1041-1046. PMID:
28183232
Article Published Date
: Nov 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
The results suggest that quercetin-rich onion may be beneficial for preventing obesity and improving liver function.
Dec 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Dec 28 ;12(1). Epub 2019 Dec 28. PMID:
31905615
Article Published Date
: Dec 27, 2019
Study Type
: Human Study
Additional Links
Substances
:
Onion
,
Quercetin
Diseases
:
Obesity
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Anti-Obesity Agents
[+]
These observations clearly indicate the beneficial effects of O. sanctum on various biochemical parameters in young overweight or obese subjects.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2017 Jul ;32(3):357-363. Epub 2016 Sep 16. PMID:
28811698
Article Published Date
: Jun 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Obesity
Pharmacological Actions
:
Hepatoprotective
[+]
This study suggested beneficial effects of combined curcuminoids and piperine supplementation on disease severity in patients with NAFLD.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 Sep ;120(9):15989-15996. Epub 2019 Jun 6. PMID:
31168845
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Piperine
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Tinospora cordifolia has a protective effect on hepatic and gastrointestinal toxicity induced by chronic and moderate alcoholism.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Alcohol Alcohol. 2016 Jan ;51(1):1-10. Epub 2015 Aug 19. PMID:
26589585
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Guduchi
Diseases
:
Alcohol Toxicity
,
Alcoholism
Pharmacological Actions
:
Gastroprotective
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Treatment of non-alcoholic steatohepatitis patients with vitamin D.
Sep 28, 2018
Click here to read the entire abstract
Pubmed Data
: Scand J Gastroenterol. 2018 Sep 29:1-7. Epub 2018 Sep 29. PMID:
30270688
Article Published Date
: Sep 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Turmeric and chicory seed supplementation can be significantly useful in management of NAFLD risk factors.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2019 Nov ;89(5-6):293-302. Epub 2019 Apr 24. PMID:
31017556
Article Published Date
: Oct 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Chicory
,
Turmeric
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
,
Risk Reduction
[+]
Vitamin E and C intake may be protective from NAFLD-related liver damage.
Jul 03, 2019
Click here to read the entire abstract
Pubmed Data
: Dig Liver Dis. 2019 Jul 4. Epub 2019 Jul 4. PMID:
31281067
Article Published Date
: Jul 03, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
,
Vitamin D
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Vitamin E and hydroxytyrosol may be a promising strategy that could be easily diet integrated to improve NAFLD-related liver damage in children.
Feb 10, 2019
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2019 Feb 11. Epub 2019 Feb 11. PMID:
30588836
Article Published Date
: Feb 10, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hydroxytyrosol
,
Vitamin E
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Vitamin E is an effective treatment for nonalcoholic steatohepatitis in HIV mono-infected patients.
Oct 15, 2019
Click here to read the entire abstract
Pubmed Data
: AIDS. 2019 Oct 16. Epub 2019 Oct 16. PMID:
31651429
Article Published Date
: Oct 15, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin E
Diseases
:
HIV Infections
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
White sesame seed oil may play an important role in GLU regulation and against deleterious effects of diabetes in humans with type 2 diabetes.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2019 Mar-Apr;38(3):235-246. Epub 2018 Sep 27. PMID:
30260748
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seed Oil
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Yogurt improves insulin resistance and liver fat in obese women with nonalcoholic fatty liver disease and metabolic syndrome.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2019 Jun 1 ;109(6):1611-1619. PMID:
31136662
Article Published Date
: May 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Insulin Resistance
,
Metabolic Syndrome X
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Zataria multiflora supplementation for 12 weeks improved insulin resistance in patients with NAFLD.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2018 Dec ;41:118-123. Epub 2018 Sep 17. PMID:
30477827
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Zataria multiflora
Diseases
:
Insulin Resistance
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.
Jun 01, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Med. 2021 Jun 2 ;10(11). Epub 2021 Jun 2. PMID:
34199421
Article Published Date
: Jun 01, 2021
Study Type
: Human Study
Additional Links
Substances
:
Zinc
Diseases
:
Hepatitis: Autoimmune
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Zinc and vitamin C oral supplementation for 1 month had an ameliorative effect on the hepatotoxicity of Aflatoxin B1 in wheat miller workers.
Jun 12, 2019
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2019 Jun 13 ;16(4). Epub 2019 Jun 13. PMID:
31199767
Article Published Date
: Jun 12, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
,
Zinc
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Aflatoxin
[+]
Apigenin and Luteolin significantly activate the PI3K/Nrf2/ARE system, and this activation may be responsible for their anti-inflammatory effects.
Apr 21, 2015
Click here to read the entire abstract
Pubmed Data
: Biopharm Drug Dispos. 2015 Apr 22. Epub 2015 Apr 22. PMID:
25904312
Article Published Date
: Apr 21, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Luteolin
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Nrf2 activation
[+]
Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.
Aug 23, 2015
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2015 Aug 24. Epub 2015 Aug 24. PMID:
26302188
Article Published Date
: Aug 23, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Lycium barbarum polysaccharides promotes mitochondrial biogenesis and energy balance in a NAFLD cell model.
Dec 06, 2021
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2021 Dec 7. Epub 2021 Dec 7. PMID:
34874519
Article Published Date
: Dec 06, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Goji
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID:
28071871
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangiferin
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Methylmercury
Problem Substances
:
Mercury
[+]
Procyanidin B2 alleviates palmitic acid-Induced injury in HepG2 cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:8920757. Epub 2021 Dec 16. PMID:
34956386
Article Published Date
: Dec 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Procyanidin B2
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
The study suggests the cytoprotective effects of Lepidium sativum seed against H2O2-induced toxicity in HepG2.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 ;54(2):314-21. Epub 2015 Apr 17. PMID:
25885937
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Garden Cress (Lepidium sativum)
Diseases
:
Hydrogen Peroxide Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
,
Hepatoprotective
[+]
A case report of severe alcoholic hepatitis effectively treated with vitamin E as an add-on to corticosteroids.
Oct 10, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intern Med. 2017 Oct 11. Epub 2017 Oct 11. PMID:
29021453
Article Published Date
: Oct 10, 2017
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alcohol Toxicity
,
Hepatitis
Pharmacological Actions
:
Hepatoprotective
[+]
After taking 30 mg artichoke leaf extract tea 3 times a day, patients bilirubin levels significantly declined at the end of the first week and all liver function tests were normalized within 2 months.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Case Reports Hepatol. 2014 ;2014:697359. Epub 2014 Sep 3. PMID:
25374729
Article Published Date
: Dec 31, 2013
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Significant Treatment Outcome
Problem Substances
:
Fluconazole
[+]
N-acetylcysteine in the management of acute liver failure from sickle cell hepatic crisis.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ACG Case Rep J. 2019 Aug ;6(8):e00161. Epub 2019 Aug 21. PMID:
31737700
Article Published Date
: Jul 31, 2019
Study Type
: Human: Case Report
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage
,
Sickle Cell Anemia
Pharmacological Actions
:
Hepatoprotective
[+]
Nonalcoholic fatty liver disease parameters were dramatically improved by plant-based diet.
Oct 17, 2019
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2019 Oct 18 ;25(11):e146-e147. PMID:
31560040
Article Published Date
: Oct 17, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Inflammatory Bowel Diseases
,
Nonalcoholic fatty liver disease (NAFLD)
,
Ulcerative Colitis
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Hepatoprotective
[+]
Novel use of N-acetylcysteine in management of tyrosine kinase inhibitor induced acute liver injury.
Nov 26, 2019
Click here to read the entire abstract
Pubmed Data
: Cureus. 2019 Nov 27 ;11(11):e6251. Epub 2019 Nov 27. PMID:
31890447
Article Published Date
: Nov 26, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Phloretin mitigates oxidative injury, inflammation and fibrogenic responses.
May 20, 2022
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2022 May 21:109062. Epub 2022 May 21. PMID:
35609858
Article Published Date
: May 20, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Phloretin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Targeting mitochondrial ROS-mediated ferroptosis by quercetin alleviates high-fat diet-induced hepatic lipotoxicity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:876550. Epub 2022 Apr 12. PMID:
35496312
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Quercetin
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
A diet rich in vitamin C and quercetin could prevent nicotine-induced toxicity.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Arh Hig Rada Toksikol. 2016 Dec 1 ;67(4):304-310. PMID:
28033106
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
,
Vitamin C
Diseases
:
Nicotine/Tobacco Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Anti-inflammatory and antioxidant effects of Apium graveolens L. extracts mitigate against fatal acetaminophen-induced acute liver toxicity.
Jul 25, 2020
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2020 Jul 26:e13399. Epub 2020 Jul 26. PMID:
32713084
Article Published Date
: Jul 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
[+]
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3
Aug 19, 2021
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2021 Aug 20. Epub 2021 Aug 20. PMID:
34417576
Article Published Date
: Aug 19, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Metabolic Diseases
,
Obesity
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2015 Oct ;59(10):1883-95. Epub 2015 Jul 20. PMID:
26108684
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Turmeric
Diseases
:
Hepatic Steatosis
,
High Fat Diet
,
Obesity
Pharmacological Actions
:
Hepatoprotective
[+]
Co-administration of N-Acetylcysteine and Acetaminophen efficiently blocks Acetaminophen toxicity.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2015 Aug ;76(5):251-8. Epub 2015 Aug 7. PMID:
26250417
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Effects of grape juice, red wine and resveratrol on liver parameters of rat submitted high-fat diet.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: An Acad Bras Cienc. 2020 ;92(2):e20191230. Epub 2020 Aug 10. PMID:
32785427
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Red Wine
,
Resveratrol
Diseases
:
High Fat Diet
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota.
Jun 19, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2020 Jun 20 ;84:108455. Epub 2020 Jun 20. PMID:
32688217
Article Published Date
: Jun 19, 2020
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
F. religisoa protects against isoniazid, rifampicin and paracetamol induced oxidative liver injury in rats.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacognosy Res. 2013 Oct ;5(4):271-6. PMID:
24174821
Article Published Date
: Sep 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Isoniazid
,
Paracetamol
[+]
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy
Nov 09, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chin Med. 2021 Nov 10 ;16(1):115. Epub 2021 Nov 10. PMID:
34758848
Article Published Date
: Nov 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.
Sep 15, 2020
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2020 Sep 16. Epub 2020 Sep 16. PMID:
32939034
Article Published Date
: Sep 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Liver Damage
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]
Moringa oleifera Lam. leaf extract might be a good alternative herbal choice in the treatment of metabolic syndrome disease.
May 14, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2020 May 15:1-7. Epub 2020 May 15. PMID:
32412306
Article Published Date
: May 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
High Fat Diet
,
High Fructose Diet
,
Metabolic Syndrome X
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2020 Dec ;81:197-208. Epub 2020 Oct 26. PMID:
33121995
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Isoniazid
[+]
Purple grape juices prevent pentylenetetrazol-induced oxidative damage in the liver and serum of Wistar rats.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2013 Feb ;33(2):120-5. Epub 2013 Jan 17. PMID:
23399662
Article Published Date
: Jan 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice
Jun 11, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Prev Med. 2017 Jun 12 ;22(1):54. Epub 2017 Jun 12. PMID:
29165178
Article Published Date
: Jun 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
The hepatoprotective effect of prazosin is comparable to N- acetylcysteine against acetaminophen induced hepatotoxicity.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Ayub Med Coll Abbottabad. 2020 Jan- Mar;32(1):28-32. PMID:
32468750
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage.
Apr 29, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2020 Apr 30:1-12. Epub 2020 Apr 30. PMID:
32349632
Article Published Date
: Apr 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
[+]
Vitexin ameliorates chronic stress plub high fat diet-induced nonalcoholic fatty liver disease by inhibiting inflammation.
Sep 04, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Sep 5 ;882:173264. Epub 2020 Jun 13. PMID:
32544504
Article Published Date
: Sep 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Vitexins
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Zingiber mioga reduces weight gain, insulin resistance and hepatic gluconeogenesis in diet-induced obese mice.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2016 Jul ;12(1):369-376. Epub 2016 May 11. PMID:
27347064
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Hepatic Steatosis
,
Obesity
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation.
Nov 29, 2020
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2020 Nov 30 ;81:153426. Epub 2020 Nov 30. PMID:
33341026
Article Published Date
: Nov 29, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammation
,
Liver Fibrosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
"Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats."
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2006 Oct ;290(1-2):61-7. Epub 2006 Aug 26. PMID:
16937016
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Chemically-Induced Liver Damage
,
Formaldehyde Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Formaldehyde
[+]
6-gingerol ameliorates age-related hepatic steatosis
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2019 Jan 1 ;362:125-135. Epub 2018 Nov 5. PMID:
30408433
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Hepatic Steatosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
6-gingerol ameliorates age-related hepatic steatosis.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2019 Jan 1 ;362:125-135. Epub 2018 Nov 5. PMID:
30408433
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Hepatic Steatosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
6-gingerol ameliorates hepatic steatosis via HNF4α/miR-467b-3p/GPAT1 cascade.
Jun 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Mol Gastroenterol Hepatol. 2021 Jun 15. Epub 2021 Jun 15. PMID:
34139323
Article Published Date
: Jun 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
6-gingerol ameliorates metabolic disorders by inhibiting hypertrophy and hyperplasia.
Jan 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Feb ;146:112491. Epub 2021 Dec 9. PMID:
34896967
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
[+]
6-gingerol, a major ingredient of ginger attenuates diethylnitrosamine-induced liver injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2021 ;2021:6661937. Epub 2021 Jan 19. PMID:
33531877
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
6-gingerol, an active ingredient of ginger, protects acetaminophen-induced liver damage in mice.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhong Xi Yi Jie He Xue Bao. 2011 Nov ;9(11):1264-9. PMID:
22088594
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
6-shogaol can be used as a therapeutic agent for preventing complications in diabetic patients.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetol Metab Syndr. 2019 ;11:15. Epub 2019 Feb 12. PMID:
30805033
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Diabetes Mellitus: Type 1
,
Diabetic Complications
Pharmacological Actions
:
Hepatoprotective
,
Pancreato Protective Agents
,
Renoprotective
[+]
A broccoli extract enriched diet increases antioxidant enzyme activities and exerts an antioxidant effect towards cholesterol oxidation in rat liver.
Apr 11, 2016
Click here to read the entire abstract
Pubmed Data
: J Steroid Biochem Mol Biol. 2016 Apr 12. Epub 2016 Apr 12. PMID:
27084531
Article Published Date
: Apr 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
Diseases
:
Cholesterol: Oxidation
,
Liver Disease: Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A combination of apple vinegar drink with Bacillus coagulans ameliorates high fat diet-induced body weight gain, insulin resistance and hepatic steatosis.
Aug 18, 2020
Click here to read the entire abstract
Pubmed Data
: Nutrients. 2020 Aug 19 ;12(9). Epub 2020 Aug 19. PMID:
32825073
Article Published Date
: Aug 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple Cider Vinegar
Diseases
:
High Fat Diet
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
A combination of five main alkaloids from Rhizoma Coptidis showed a synergetic cholesterol-lowering efficacy.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Apr 15 ;151:50-60. Epub 2016 Feb 11. PMID:
26876917
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Coptidis rhizoma
Diseases
:
Cardiovascular Disease: Prevention
,
Hypercholesterolemia
,
Hyperlipidemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Natural Substance Synergy
[+]
A combination of flaxseed oil and astaxanthin may reduce NAFLD by reversing hepatic steatosis and reducing lipid accumulation and oxidative stress.
Mar 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 13 ;9(3). Epub 2017 Mar 13. PMID:
28335388
Article Published Date
: Mar 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
,
Flaxseed Oil
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Hypolipidemic
[+]
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease.
Jan 08, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Jan 9 ;58:152824. Epub 2019 Jan 9. PMID:
30836218
Article Published Date
: Jan 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Kudzu
,
Milk Thistle
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypolipidemic
[+]
A combination strategy of thymoquinone and curcumin might be considered as a potential antidote in combating liver injury induced by acetaminophen.
Mar 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Folia Morphol (Warsz). 2019 Mar 5. Epub 2019 Mar 5. PMID:
30835338
Article Published Date
: Mar 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Thymoquinone
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A comparative study of the hepatoprotective effect of Centella asiatica extract on lipopolysaccharide/d-galactosamine-induced acute liver injury.
Nov 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Nov 15 ;13(11). Epub 2021 Nov 15. PMID:
34836346
Article Published Date
: Nov 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A curcumin-phospholipid complex works synergistically to protect the livers of rats following chemical exposure.
Feb 07, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Pharm. 2007 Feb 7;330(1-2):155-63. Epub 2006 Sep 23. PMID:
17112692
Article Published Date
: Feb 07, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Phosphatidylcholine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A diet rich in saturated fat to a diet rich in unsaturated fat can attenuate NAFLD and atherosclerosis development.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(9):e0139196. Epub 2015 Sep 25. PMID:
26405765
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pumpkin Seeds
Diseases
:
Atherosclerosis
,
Dyslipidemias
,
Inflammation
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
A flavonoids rich bitter orange extract could ameliorate ethanol induced liver injury in mice.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2015 Oct ;29(10):1577-84. Epub 2015 Jul 14. PMID:
26178909
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Plant Extracts
[+]
A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Dec;46(12):3714-20. Epub 2008 Oct 1. PMID:
18938206
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
,
Pumpkin Seed Oil/Meal
Diseases
:
Arteriosclerosis
,
High Cholesterol
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:387. Epub 2018 Apr 20. PMID:
29731716
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
A herbal complex is an effective herbal formulation in the attenuation of obesity and obesity-induced metabolic dysfunction including NAFLD.
Jan 07, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Jan 8 ;26(2). Epub 2021 Jan 8. PMID:
33435558
Article Published Date
: Jan 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cinnamon
,
Hawthorn
,
Raspberry
Diseases
:
Metabolic Diseases
,
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Enzyme Inhibitors
,
Hepatoprotective
,
Hypolipidemic
[+]
A hydroalcoholic extract of watercress could be a beneficial new curative agent for cholestatic liver damage.
Apr 22, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 Apr 23. Epub 2019 Apr 23. PMID:
31016763
Article Published Date
: Apr 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Watercress
Diseases
:
Hepatitis: Cholestatic
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2012 ;7(6):e38797. Epub 2012 Jun 7. PMID:
22685607
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Fatty Liver
,
Insulin: Elevated
,
Triglycerides: Elevated
Pharmacological Actions
:
Hepatoprotective
[+]
A maple syrup extract alleviates liver injury in type 2 diabetic model mice.
Oct 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res. 2019 Oct 24 ;73:97-101. Epub 2019 Oct 24. PMID:
31945627
Article Published Date
: Oct 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Maple Syrup
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A methanolic extract of pomegranate peel ameliorated the hepatic damage caused by acetaminophen.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pak Med Assoc. 2016 Jul ;66(7):859-63. PMID:
27427136
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A mixture of curcumin, hesperidin and rutin ameliorates hepatic oxidative stress caused by STZ-induced hyperglycemia.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26265154
Article Published Date
: Aug 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Hesperidin
,
Rutin
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperglycemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
[+]
A new possible mechanism by which punicalagin protects against liver injury induced by type 2 diabetes mellitus.
Nov 06, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Nov 7. Epub 2019 Nov 7. PMID:
31698901
Article Published Date
: Nov 06, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Diabetes Mellitus: Type 2
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2021 ;65. Epub 2021 Jul 1. PMID:
34262422
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Autophagy Up-regulation
,
Gastrointestinal Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A novel acidic polysaccharide from the residue of Panax notoginseng and its hepatoprotective effect on alcoholic liver damage in mice.
Feb 05, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2020 Feb 6 ;149:1084-1097. Epub 2020 Feb 6. PMID:
32035151
Article Published Date
: Feb 05, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Panax Notoginseng
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Polysaccharides
[+]
A phenolics rich extract of ginger had protective effects against Aflatoxin B1-induced oxidative stress and hepatotoxicity.
May 01, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 May 2 ;91:415-424. Epub 2017 May 2. PMID:
28475920
Article Published Date
: May 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Gingerol
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Aflatoxin
[+]
A pine nut polysaccharide is a promising functional food to prevent alcohol induced-liver injury.
Nov 08, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Nov 9. Epub 2019 Nov 9. PMID:
31712149
Article Published Date
: Nov 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pine Nut
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
A polyphenol extract from red grapes redues fat content in an animal model of non-alcoholic liver disease.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Dec;104(12):1760-70. Epub 2010 Aug 2. PMID:
20673376
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
,
Resveratrol
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A polysaccharide from Pleurotus nebrodensis might be a promising candidate for preventing hepatic I/R injury.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2017 Dec ;105(Pt 1):447-451. Epub 2017 Jul 11. PMID:
28709897
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pleurotus nebrodensis
Diseases
:
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
A polysaccharide rich ginkgo biloba extract has a protective effect against HFD-induced NAFLD.
Jun 02, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2015 Jun 3. Epub 2015 Jun 3. PMID:
