Hypoxia inducible factor-1 alpha HIF-1α inhibitor

Name	AC	CK
Ginsenosides	15	26
Curcumin	7	18
Tanshinone IIA	11	16
Berberine	8	11
Flavonoids	6	10
Goji	1	10
Resveratrol	6	10
EGCG (Epigallocatechin gallate)	5	9
Paeoniflorin	6	9
Apigenin	5	8
Luteolin	5	8
Astragaloside	3	7
Beta-Elemene	5	7
Puerarin	3	7
Gingerol	3	6
Ginkgo biloba	3	6
Pomegranate	3	6
Vitamin C	5	6
Bee Venom	3	5
Quercetin	3	5
Sulforaphane	4	5
Wogonin	4	5
6-Shogaol	2	4
Bacopa	2	4
Chrysin	3	4
Lycopene	2	4
Melatonin	4	4
Nicotinamide Mononucleotide	2	4
Panax Notoginseng	2	4
Sesamin	2	4
Shikonin	3	4
Skullcap: Chinese	2	4
Thymoquinone	4	4
Andrographolide	3	3
Bifidobacterium Bifidum	1	3
Cannabidiol	3	3
Capsaicin	3	3
Celastrol	2	3
Echinacea	2	3
Honokiol	2	3
Lactococcus lactis	1	3
Mangiferin	3	3
Parthenolide	3	3
Salvia miltiorrhiza	2	3
Ursolic Acid	3	3
Vanillic Acid	1	3
Verbascoside	2	3
Vitexins	2	3
2-Methoxyestradiol	1	2
Adlay	1	2
Angelica	1	2
Anthocyanins	1	2
Artesunate	1	2
Astragalus	1	2
Basil	1	2
Bee Propolis	1	2
Broccoli Sprouts	2	2
Cinnamaldehyde	2	2
Corn: Purple	1	2
Crocin	1	2
Cucurbitacin B	1	2
Curcumol	1	2
DHA (Docosahexaenoic Acid)	1	2
Deguelin	2	2
Diosmin	1	2
Ellagic Acid	2	2
Eriodictyol	1	2
Ferulic acid	1	2
Fisetin	2	2
Flaxseed Oil	1	2
Ginseng (Korean)	2	2
Grape Seed Extract	1	2
Huaier (Trametes robiniophila murr)	1	2
Isoquercitrin	1	2
Lactobacillus rhamnosus GG	1	2
Licorice	1	2
Lingans	1	2
Moringa oleifera	2	2
Myricetin	1	2
Neem	2	2
Oleuropein	1	2
Oligosaccharides	1	2
Paeonol	2	2
Plantago asiatica	1	2
Polyphenols	2	2
Pterostilbene	2	2
Saccharomyces Boulardii	1	2
Safranal	1	2
Tomato	1	2
Vanillin	1	2
4-Shogaol	1	1
Allicin	1	1
Andrographis	1	1
Artemisinin	1	1
Ashwagandha	1	1
Astaxanthin	1	1
Avenanthramides	1	1
Banana	1	1
Barberry	1	1
Beet	1	1
Berbamine	1	1
Betulinic acid	1	1
Black Tea	1	1
Bufalin	1	1
Caffeic Acid	1	1
Cannabinoids	1	1
Cardamonin	1	1
Cinnamon	1	1
Citrus naringin	1	1
Coumestrol	1	1
Dandelion	1	1
Delphinidin	1	1
Diosgenin	1	1
Emodin	1	1
Formononetin	1	1
Fucoidan	1	1
Galbanic Acid	1	1
Gallic Acid	1	1
Garlic: Aged	1	1
Genistein	1	1
Geraniol	1	1
Grape	1	1
Graviola	1	1
Gynostemma	1	1
Harmine	1	1
Hops	1	1
Ketone Bodies	1	1
Liquiritigenin	1	1
Modified Citrus Pectin	1	1
Oats	1	1
Organosulfur Compounds	1	1
Oridonin	1	1
Oxaloacetate	1	1
Panaxadiol	1	1
Patchouli	1	1
Phloretin	1	1
Piceatannol	1	1
Piperlongumine	1	1
Plantago	1	1
Plumbagin	1	1
Proanthocyanidins	1	1
Rutin	1	1
Safflower	1	1
Silibinin	1	1
Terminalia chebula	1	1
Tetrahydrocurcumin	1	1
Theaflavins	1	1
Turmeric	1	1
Vitamin E	1	1
Vitamin K2	1	1
Xanthohumol	1	1
beta-Carotene	1	1

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Pubmed Data : Biochem Biophys Res Commun. 2024 May 16 ;721:150130. Epub 2024 May 16. PMID: 38761750

Article Published Date : May 15, 2024

Study Type : Animal Study

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Substances : Apigenin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.Dec 31, 2021

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Pubmed Data : Biomed Pharmacother. 2023 May ;161:114534. Epub 2023 Mar 16. PMID: 36933376

Article Published Date : Apr 30, 2023

Study Type : Animal Study

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Substances : Chrysin

Diseases : Cerebral Ischemia, Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Neuroprotective Agents

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Cucurbitacin B inhibits HIF-1α and attenuates non-small cell lung cancer via ZFP91.Dec 31, 2024

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Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility.Nov 30, 2022

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Pubmed Data : Biomed Pharmacother. 2022 Dec ;156:113743. Epub 2022 Oct 14. PMID: 36252358

Article Published Date : Nov 30, 2022

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Infertility: Female

Pharmacological Actions : Fertility Agents: Female, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Impact of berberine on some epigenetic, transcription regulation and inflammatory biomarkers in a mice model of epilepsy.Sep 30, 2021

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Pubmed Data : Rep Biochem Mol Biol. 2021 Oct ;10(3):362-372. PMID: 34981012

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Pubmed Data : J Comp Neurol. 2012 Sep 1 ;520(13):2903-16. PMID: 22351621

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Pubmed Data : Mol Med Rep. 2018 Dec ;18(6):5652-5662. Epub 2018 Oct 30. PMID: 30387820

Article Published Date : Nov 30, 2018

Study Type : Animal Study

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Substances : Saccharomyces Boulardii

Diseases : Colitis

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Mechanism of hyperbaric oxygen therapy downregulating H-type angiogenesis in subchondral bone of knee osteoarthritis.Jan 21, 2025

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Pubmed Data : Int J Mol Sci. 2024 Sep 30 ;25(19). Epub 2024 Sep 30. PMID: 39408861

Article Published Date : Sep 29, 2024

Study Type : Animal Study

Additional Links

Substances : Nicotinamide Mononucleotide

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Pancreato Protective Agents

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Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD+/SIRT1 axis.Dec 31, 2022

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Pubmed Data : Cureus. 2024 Jan ;16(1):e51997. Epub 2024 Jan 10. PMID: 38205087

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Lingans

Diseases : Liver Cancer

Pharmacological Actions : Chemopreventive, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Safranal inhibits angiogenesis via targeting HIF-1α/VEGF machinery.Dec 31, 2020

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Pubmed Data : Nutr Cancer. 2015 Nov-Dec;67(8):1268-75. Epub 2015 Oct 16. PMID: 26474105

Article Published Date : Oct 31, 2015

Study Type : Animal Study

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Substances : Lycopene, Tomato

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Anticarcinogenic Agents, Chemopreventive, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Additional Keywords : Natural Substance/Drug Synergy

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Phenolic compound ellagic acid inhibits mitochondrial respiration and tumor growth in lung cancer.Jun 30, 2020

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Pubmed Data : Food Funct. 2020 Jul 1 ;11(7):6332-6339. Epub 2020 Jul 1. PMID: 32608435

Article Published Date : Jun 30, 2020

Study Type : In Vitro Study

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Substances : Ellagic Acid

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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15,16-dihydrotanshinone I inhibits EOMA cells proliferation by interfering in posttranscriptional processing of hypoxia-inducible factor 1.Dec 31, 2020

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Pubmed Data : J Cancer Res Clin Oncol. 2022 Aug 12. Epub 2022 Aug 12. PMID: 35960375

Article Published Date : Aug 11, 2022

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-metastatic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Wnt/β-catenin signaling pathway modulation

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Cannabidiol suppresses angiogenesis and stemness of breast cancer cells.Nov 11, 2021

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Pubmed Data : Cancers (Basel). 2021 Nov 12 ;13(22). Epub 2021 Nov 12. PMID: 34830821

Article Published Date : Nov 11, 2021

Study Type : In Vitro Study

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Substances : Cannabidiol

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Pubmed Data : Biofactors. 2019 Mar 10. Epub 2019 Mar 10. PMID: 30854715

Article Published Date : Mar 09, 2019

Study Type : In Vitro Study

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Substances : Cinnamaldehyde

Diseases : Melanoma, Skin Cancer

Pharmacological Actions : Anti-metastatic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Cinnamaldehyde downregulation of Sept9 inhibits glioma progression.Dec 31, 2021

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Pubmed Data : Oncol Lett. 2019 Sep ;18(3):2248-2253. Epub 2019 Jul 5. PMID: 31452725

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

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Substances : Formononetin

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

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Fucoidan inhibits epithelial-to-mesenchymal transition via regulation of the HIF-1α pathway in mammary cancer cells under hypoxia.Jun 30, 2019

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Pubmed Data : Cell Physiol Biochem. 2010 ;26(6):849-58. Epub 2011 Jan 4. PMID: 21220916

Article Published Date : Dec 31, 2009

Study Type : In Vitro Study

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Substances : Ginsenosides

Diseases : Cancers: All

Pharmacological Actions : Anti-Angiogenic, Cyclooxygenase 2 Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Ginsenoside 20(S)-Rg3 suppresses ovarian cancer migration.Apr 30, 2017

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Pubmed Data : Tumour Biol. 2017 May ;39(5):1010428317692225. PMID: 28459376

Article Published Date : Apr 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Ovarian Cancer

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor

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Ginsenoside 20(S)-Rg3 targets HIF-1α to block hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cells.Dec 31, 2013

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Pubmed Data : Food Chem Toxicol. 2020 Jul ;141:111436. Epub 2020 May 18. PMID: 32439592

Article Published Date : Jun 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Nrf2 activation

Problem Substances : Ochratoxin A

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Luteolin is a potential therapeutic candidate for melanoma.Jan 16, 2019

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Pubmed Data : Int J Biol Sci. 2021 ;17(14):3728-3744. Epub 2021 Aug 27. PMID: 34671196

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Pubmed Data : Cancer Med. 2019 Aug ;8(9):4315-4329. Epub 2019 Jun 13. PMID: 31197964

Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.Nov 30, 2014

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Pubmed Data : Fitoterapia. 2014 Dec ;99:318-27. Epub 2014 Oct 16. PMID: 25454463

Article Published Date : Nov 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : Paeoniflorin

Diseases : Liver Cirrhosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Paeoniflorin is a natural product with multiple targets in liver diseases.Dec 31, 2019

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Pubmed Data : J Complement Integr Med. 2023 Sep 18. Epub 2023 Sep 18. PMID: 37712721

Article Published Date : Sep 17, 2023

Study Type : Review

Additional Links

Substances : Moringa oleifera

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Pterostilbene nanoparticles downregulate hypoxia-inducible factors in hepatoma cells under hypoxic conditions.Dec 31, 2020

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Pubmed Data : Int J Nanomedicine. 2021 ;16:867-879. Epub 2021 Feb 5. PMID: 33574667

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Pterostilbene

Diseases : Liver Cancer

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Resveratrol prevents bisphenol A-induced autism, type 2 diabetes mellitus and metabolic syndrome.Jan 31, 2016

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Pubmed Data : Nutrition. 2016 Feb ;32(2):174-8. Epub 2015 Sep 25. PMID: 26706021

Article Published Date : Jan 31, 2016

Study Type : Review

Additional Links

Substances : Resveratrol

Diseases : Autism Spectrum Disorders, Bisphenol-A Toxicity, Diabetes Mellitus: Type 2: Prevention, Metabolic Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Microbiota, Risk Reduction

Problem Substances : Bisphenol A

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Rg3 enhanced the radiosensitivity of human oesophageal carcinoma cell lines cultured under hypoxic conditions.May 31, 2014

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Pubmed Data : Biochem Biophys Res Commun. 2020 Jan 13. Epub 2020 Jan 13. PMID: 31948750

Article Published Date : Jan 12, 2020

Study Type : In Vitro Study

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Substances : Betulinic acid

Diseases : Cervical Cancer

Pharmacological Actions : Chemotherapeutic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC.Apr 18, 2024

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Pubmed Data : Toxicol Appl Pharmacol. 2024 Apr 19 ;486:116938. Epub 2024 Apr 19. PMID: 38642809

Article Published Date : Apr 18, 2024

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

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Synergistic effect of chrysin and radiotherapy against triple-negative breast cancer (TNBC) cell lines.Mar 24, 2023

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Pubmed Data : Clin Transl Oncol. 2023 Mar 25. Epub 2023 Mar 25. PMID: 36964888

Article Published Date : Mar 24, 2023

Study Type : In Vitro Study

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Substances : Chrysin

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Radiosensitizer

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Pubmed Data : PLoS One. 2013 ;8(10):e76918. Epub 2013 Oct 21. PMID: 24204703

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Cancer Metastasis, Glioma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antineoplastic Agents, Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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The results of this study suggests a positive role for ascorbic acid in regulating HIF-1α in melanoma.Dec 31, 2014

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Pubmed Data : Phytother Res. 2012 Aug ;26(8):1133-41. Epub 2011 Dec 14. PMID: 22170854

Article Published Date : Jul 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Liquiritigenin

Diseases : Cervical Cancer

Pharmacological Actions : Anti-Angiogenic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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This study suggests that ginsenoside Rg3 has a therapeutic potential targeting breast cancer stem cells.Jun 30, 2019

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β‑elemene inhibits the generation of peritoneum effusion in pancreatic cancer.Nov 30, 2019

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Pubmed Data : Oncol Rep. 2019 Dec ;42(6):2561-2571. Epub 2019 Oct 9. PMID: 31638231

Article Published Date : Nov 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Beta-Elemene

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor A Inhibitor

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View the Evidence: 258 Abstracts with Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor Research

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Both NBH and HBOT can effectively improve cognitive outcome for patients with mild TBI.Sep 14, 2023

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Hyperbaric oxygen therapy can ameliorate the EMT phenomenon in keloid tissue.Jun 30, 2018

Lycium barbarum polysaccharide inhibited hypoxia-inducible factor 1 in COPD patients.Dec 31, 2019

The effects of nanocurcumin on immune-related factors in the ankylosing spondylitis patients.Mar 18, 2025

DMT can increase survival and alleviate cellular stress in hypoxic environments.Dec 31, 2015

6-shogaol alleviates endotoxin-induced uveitis.Jun 30, 2025

Anticancer effects of tanshinone IIA in bladder urothelial carcinoma.Apr 30, 2024

Astragaloside IV in hypoxic pulmonary hypertension.Aug 01, 2022

Bifidobacterium bifidum and Lactococcus lactis strains with synergistic effects alleviates colitis-associated colorectal cancer.Sep 24, 2024

Luteolin attenuates lupus nephritis by regulating macrophage oxidative stress via HIF-1α pathway.Aug 14, 2023

Puerarin suppresses hypoxia-induced vascular endothelial growth factor upregulation in human retinal pigmented epithelial cells.Apr 30, 2022

Reduced HIF-1α stability induced by 6-gingerol inhibits lung cancer growth.Mar 23, 2022

Resveratrol alleviates MSU-induced gouty arthritis.Jul 30, 2023

Scutellarin suppresses Mycobacterium tuberculosis-induced pyroptosis in macrophages.Nov 30, 2025

Sesamin inhibits hypoxia-stimulated angiogenesis.Aug 29, 2022

Tanshinone IIA attenuates airway inflammation and airway remodeling in bronchial asthma.Jan 19, 2026

Vanillic acid is an effective inhibitor of HIF-1α and provides new perspectives into the mechanism of its antitumor activity.Jan 21, 2019

Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.Sep 15, 2020

2-Methoxyestradiol attenuates testosterone-induced benign prostate hyperplasia.Dec 31, 2017

A Huaier polysaccharide restrains hepatocellular carcinoma growth and metastasis.Mar 31, 2015

A purple corn extract may be a potent therapeutic agent targeting abnormal angiogenesis in diabetic nephropathy leading to kidney failure.Dec 31, 2012

Adlay and cisplatin led to pronounced antitumor activity in mice with Lewis lung carcinoma.May 31, 2018

An extract of Bacopa monnieri restored the memory in CoCl2-hypoxia mimetic mice.Dec 31, 2014

Antioxidant-rich extract from plantaginis semen Ameliorates diabetic retinal injury in a streptozotocin-induced diabetic rat model.Sep 17, 2016

Antitumor activity of ferulic acid against Ehrlich solid carcinoma in rats via affecting hypoxia, oxidative stress and cell proliferation.Jun 30, 2023

Apigenin attenuates pulmonary hypertension.Jan 09, 2020

Apigenin could improve hypertensive cardiac hypertrophy and abnormal myocardial glucolipid metabolism in rats.Mar 17, 2016

Apigenin intervenes in liver fibrosis by regulating PKM2-HIF-1α mediated oxidative stress.May 15, 2024

Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.Dec 31, 2021

Astragaloside IV promotes cerebral tissue restoration.Jul 05, 2024

Astragaloside IV restrains pyroptosis and fibrotic development of pulmonary artery smooth muscle cells to ameliorate pulmonary artery hypertension.Oct 11, 2023

Bacopa monnieri extract diminish hypoxia-induced anxiety.Jan 23, 2025

Basil polysaccharide inhibits hypoxia-induced hepatocellular carcinoma metastasis and progression.Jun 24, 2019

Beneficial impact of epigallocatechingallate on LDL-C through PCSK9/LDLR pathway by blocking HNF1α and activating FoxO3a.May 11, 2020

Berberine improves insulin-induced diabetic retinopathy in type I and II diabetes.Dec 31, 2020

Berberine may exert antitumor effects by suppressing tumor growth and elevating the intestinal mucosal permeability.Oct 31, 2018

Celastrol protects against cerebral ischemia/reperfusion injury.Dec 31, 2021

Chrysin protects against cerebral ischemia-reperfusion injury in hippocampus.Apr 30, 2023

Cucurbitacin B inhibits HIF-1α and attenuates non-small cell lung cancer via ZFP91.Dec 31, 2024

Curcumol might represent a promising lead compound for the development of new targeted anti-cancer therapeutics.Apr 08, 2020

Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury.Jun 30, 2021

Dihydrotanshinone I inhibits the translational expression of hypoxia-inducible factor-1α.Oct 04, 2015

Diosmin potentially attenuates renal ferroptosis and fibrosis.May 31, 2025

Down-regulation of survivin and hypoxia-inducible factor-1 α by β-elemene enhances the radiosensitivity of lung adenocarcinoma xenograft.Jan 31, 2012

Effect of eriodictyol on collagen-induced arthritis in rats by Akt/HIF-1α pathway.Dec 31, 2019

Effects of echinacoside on ehrlich carcinoma in rats by targeting proliferation, hypoxia and inflammation.Sep 30, 2023

EGCG could attenuate testosterone-induced benign prostatic hyperplasia and fibrosis.Aug 31, 2018

Electroacupuncture enhances cerebral blood perfusion by inhibiting HIF-1α in rat subarachnoid hemorrhage.Sep 14, 2024

Epigallocatechin gallate relieves asthmatic symptoms.May 27, 2022

Epigallocatechin-3-gallate decreases hypoxia-inducible factor-1 in pancreatic cancer cells. Mar 02, 2023

Flaxseed oil alleviates chronic high fat diet induced insulin resistance.Nov 07, 2017

Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis.Jun 30, 2023

Ginkgo biloba extract promotes Treg differentiation to ameliorate ischemic stroke.Nov 30, 2023

Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.Jun 17, 2016

Grape seed proanthocyanidine extract administration may decrease periodontal inflammation and alveolar bone loss.May 31, 2018

High concentrations of L-ascorbic acid specifically inhibit the growth of human leukemic cells.Dec 31, 2012

Honokiol attenuates choroidal neovascularization.Sep 13, 2023

Human milk oligosaccharides activate epidermal growth factor receptor and protect against hypoxia-induced injuries.Jan 07, 2020

Hyperbaric oxygen therapy could inhibit glioma cell proliferation and inflammatory cell infiltration.Oct 31, 2016

Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility.Nov 30, 2022

Impact of berberine on some epigenetic, transcription regulation and inflammatory biomarkers in a mice model of epilepsy.Sep 30, 2021

Impact of licochalcone A on the progression of diabetic nephropathy in type 2 diabetes mellitus.Oct 31, 2021

Isoquercitrin may be considered a safer alternative for managing osteoporosis.Dec 14, 2019

Liposomal curcumin inhibits hypoxia-induced angiogenesis.Dec 31, 2014

Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury.Aug 31, 2012

Luteolin suppresses sepsis-induced cold-inducible RNA-binding protein production and lung injury.Jan 31, 2021

Lycopene prevents DEHP-induced liver lipid metabolism disorder.Oct 13, 2020

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis.Nov 30, 2018

Mechanism of hyperbaric oxygen therapy downregulating H-type angiogenesis in subchondral bone of knee osteoarthritis.Jan 21, 2025

Mechanistic insights on the effect of crocin on atherosclerosis.Jul 31, 2022

Melittin exerts an antitumor effect on non‑small cell lung cancer cells.Aug 31, 2017

Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

View the Evidence:
258 Abstracts with Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor Research