Immunosuppressive Agents

Name	AC	CK
Cannabinoids	3	12
Curcumin	7	10
Lactobacillus paracasei	1	10
Lactobacillus plantarum	1	10
Cannabidiol	4	5
Chrysin	1	5
Vitamin K2	1	5
Arctigenin	2	4
Chlorella (Algae)	1	3
Delta-tetrahydrocannabinol (THC)	2	3
Poria cocos	2	3
Tripterygium wilfordii	2	3
Artichoke	1	2
Berberine	1	2
Burdock	1	2
Cannabis	1	2
Geraniol	1	2
Luteolin	1	2
Mangosteen	1	2
Mugwort	1	2
Paeoniflorin	1	2
Panax Ginseng	1	2
Patchouli	1	2
Piperine	1	2
Resveratrol	2	2
Sinomenine	1	2
Soursop	1	2
Zerumbone	1	2
Acorus calamus	1	1
Arnica	1	1
Celastrol	1	1
Echinacea	1	1
Endocannabinoids	1	1
Flavonoids	1	1
Helenalin	1	1
Licorice	1	1
Marijuana	1	1
Naringenin	1	1
Phloretin	1	1
Piperlongumine	1	1
Prunella vulgaris	1	1
Quercetin	1	1
Stilbenes	1	1

[+]

Immunosuppressive effects of two probiotics, Lactobacillus paracasei DSM 13434 and Lactobacillus plantarum DSM 15312.Feb 19, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Allergy Asthma Immunol. 2023 Feb 20 ;22(1):34-45. Epub 2023 Feb 20. PMID: 37002629

Article Published Date : Feb 19, 2023

Study Type : Human Study

Additional Links

Substances : Lactobacillus paracasei, Lactobacillus plantarum

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents, Interferon Gamma Reducer, Transforming growth factor beta (TGF-β) inhibitor

[+]

These results reveal an immunosuppressive effect of cannabinoid preparations.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Mol Neurosci. 2017 ;10:14. Epub 2017 Jan 24. PMID: 28174520

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Cannabinoids

Diseases : Inflammation, Pancreatitis: Chronic

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

Additional Keywords : Anti-Inflammatory Agents, Cannabinoids, Immunosuppressive Agents, Inflammation, Pancreatitis: Chronic

[+]

Chrysin ameliorated experimental autoimmune encephalomyelitis, an animal model of MS, by reducing CNS inflammation and demyelination.Nov 14, 2015

Click here to read the entire abstract

Pubmed Data : J Neuroimmunol. 2015 Nov 15 ;288:13-20. Epub 2015 Sep 1. PMID: 26531689

Article Published Date : Nov 14, 2015

Study Type : Human In Vitro

Additional Links

Substances : Chrysin

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

[+]

Vitamin K2 immunosuppressive effect on pediatric patients with atopic dermatitis.Nov 30, 2019

Click here to read the entire abstract

Pubmed Data : Pediatr Int. 2019 Dec ;61(12):1188-1195. Epub 2019 Dec 13. PMID: 31560147

Article Published Date : Nov 30, 2019

Study Type : Human In Vitro

Additional Links

Substances : Vitamin K2

Diseases : Atopic Dermatitis

Pharmacological Actions : Immunosuppressive Agents

[+]

Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum.May 31, 2003

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Pubmed Data : Phytother Res. 2003 Jun ;17(6):665-70. PMID: 12820237

Article Published Date : May 31, 2003

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Chlorella (Algae)

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Immunostimulatory, Immunosuppressive Agents

Additional Keywords : Plant Extracts

[+]

Alcohol may contribute to Klebsiella pneumoniae infection by down-regulating interleukin-17. Jun 01, 2001

Click here to read the entire abstract

Pubmed Data : Alcohol Clin Exp Res. 2001 Jun;25(6):872-81. PMID: 11410724

Article Published Date : Jun 01, 2001

Study Type : Animal Study

Additional Links

Diseases : Alcohol Toxicity , Klebsiella Infections

Pharmacological Actions : Immunosuppressive Agents, Interleukin-17 upregulation

Additional Keywords : Diseases that are Linked

[+]

An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells.Aug 30, 2011

Click here to read the entire abstract

Pubmed Data : Immunol Lett. 2011 Aug 30;138(2):169-78. Epub 2011 Apr 15. PMID: 21524666

Article Published Date : Aug 30, 2011

Study Type : Animal Study

Additional Links

Substances : Panax Ginseng

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory: Regulatory T Cell Up-Regulation, Immunosuppressive Agents

[+]

Arctigenin could be a powerful drug candidate for acute hepatitis through immune suppression.Mar 22, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Mar 23 ;102:464-471. Epub 2018 Mar 23. PMID: 29579707

Article Published Date : Mar 22, 2018

Study Type : Animal Study

Additional Links

Substances : Arctigenin

Diseases : Hepatitis, Hepatitis: Lectin-Induced (concanavalin)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Immunosuppressive Agents

[+]

Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.Oct 05, 2015

Click here to read the entire abstract

Pubmed Data : Mol Neurobiol. 2015 Oct 6. Epub 2015 Oct 6. PMID: 26440666

Article Published Date : Oct 05, 2015

Study Type : Animal Study

Additional Links

Substances : Arctigenin, Burdock

Diseases : Autoimmune Diseases, Brain Inflammation , Multiple Sclerosis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents

[+]

Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.Aug 14, 2000

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Proc Natl Acad Sci U S A. 2000 Aug 15 ;97(17):9561-6. PMID: 10920191

Article Published Date : Aug 14, 2000

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Arthritis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin appears to have therapeutic value as an immunosuppressive/anti-rejection agent.Jun 01, 2010

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Pubmed Data : Exp Clin Transplant. 2010 Jun;8(2):161-71. PMID: 20565374

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Kidney Transplant, Organ Transplantation

Pharmacological Actions : Immunosuppressive Agents, NF-kappaB Inhibitor

[+]

Curcumin has a novel synergistic effect with the drug cyclosporine as an immunosuppressive. Jun 01, 2003

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Pubmed Data : Transplant Proc. 2003 Jun;35(4):1603-5. PMID: 12826232

Article Published Date : Jun 01, 2003

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Organ Transplantation: Heart

Pharmacological Actions : Immunosuppressive Agents

Additional Keywords : Drug Synergy

[+]

Curcumin has variable immunomodulatory effects.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2005;25(2):137-40. PMID: 16116955

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Immunomodulatory, Immunostimulatory, Immunosuppressive Agents

[+]

Geraniol represents a valuable asset against colitis alone or in combination with the conventional anti-colitic therapies.Aug 31, 2015

Click here to read the entire abstract

Pubmed Data : Life Sci. 2015 Sep 1 ;136:142-50. Epub 2015 Jul 10. PMID: 26165751

Article Published Date : Aug 31, 2015

Study Type : Animal Study

Additional Links

Substances : Geraniol

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunosuppressive Agents, NF-kappaB Inhibitor, Wnt/β-catenin signaling pathway modulation

[+]

Immunomodulatory effect of Cynara scolymus (artichoke) in rats.Oct 23, 2018

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Pubmed Data : Phytother Res. 2018 Oct 24. Epub 2018 Oct 24. PMID: 30353592

Article Published Date : Oct 23, 2018

Study Type : Animal Study

Additional Links

Substances : Artichoke

Pharmacological Actions : Immunomodulatory, Immunosuppressive Agents

[+]

Immunosuppression by piperine as a regulator of the NLRP3 inflammasome.Jan 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Vet World. 2022 Feb ;15(2):288-298. Epub 2022 Feb 11. PMID: 35400961

Article Published Date : Jan 31, 2022

Study Type : Animal Study

Additional Links

Substances : Piperine

Diseases : Arthritis

Pharmacological Actions : Immunosuppressive Agents

[+]

Immunosuppressive effect of sinomenine in an allergic rhinitis mouse model.Apr 30, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2017 May ;13(5):2405-2410. Epub 2017 Mar 20. PMID: 28565855

Article Published Date : Apr 30, 2017

Study Type : Animal Study

Additional Links

Substances : Sinomenine

Diseases : Allergic Rhinitis

Pharmacological Actions : Immunosuppressive Agents, Interleukin-4 downregulation, Transforming growth factor beta (TGF-β) upregulation

[+]

Immunosuppressive effects of Annona muricata leaf extract on cellular and humoral immune responses.Dec 31, 2022

Click here to read the entire abstract

Pubmed Data : Curr Pharm Biotechnol. 2023 ;24(11):1465-1477. PMID: 36545731

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Soursop

Pharmacological Actions : Immunosuppressive Agents

Additional Keywords : Plant Extracts

[+]

Isogarcinol is a promising immunosuppressive agent for treating psoriasis.Jan 31, 2017

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID: 28081600

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Mangosteen

Diseases : Lipopolysaccharide-Induced Toxicity, Psoriasis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-23 Downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Modulation of gut microbiota mediates berberine-induced expansion of immuno-suppressive cells to against alcoholic liver disease.Jul 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Transl Med. 2020 Aug ;10(4):e112. Epub 2020 Aug 13. PMID: 32790968

Article Published Date : Jul 31, 2020

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Immunosuppressive Agents

[+]

Mugwort (Artemisa vulgaris) demonstrates immunosuppressive activity which may be beneficial in the treatment of autoimmune diseases. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Immunopharmacol Immunotoxicol. 2009;31(4):625-30. PMID: 19874232

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Mugwort

Diseases : Autoimmune Diseases

Pharmacological Actions : Immunosuppressive Agents

[+]

Paeoniflorin attenuates the allergic contact dermatitis response.May 05, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int Immunopharmacol. 2021 May 6 ;96:107687. Epub 2021 May 6. PMID: 33965879

Article Published Date : May 05, 2021

Study Type : Animal Study

Additional Links

Substances : Paeoniflorin

Diseases : Dermatitis: Contact

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

[+]

Poria cocos bark extract has potential as an oral immune suppressor for the treatment of atopic dermatitis and food allergy.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2016 ;2016:3472608. Epub 2016 Jun 29. PMID: 27445434

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Poria cocos

Diseases : Atopic Dermatitis, Female, Food Allergies

Pharmacological Actions : Immunomodulatory, Immunosuppressive Agents

Additional Keywords : Plant Extracts

[+]

T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis.Sep 30, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2017 Oct ;16(4):4511-4520. Epub 2017 Aug 2. PMID: 28791344

Article Published Date : Sep 30, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Patchouli

Pharmacological Actions : Immunosuppressive Agents

Additional Keywords : Plant Extracts

[+]

The current study clearly demonstrates that exposure to THC leads to suppression of the immune response.Jul 31, 2002

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pharmacol Exp Ther. 2002 Aug ;302(2):451-65. PMID: 12130702

Article Published Date : Jul 31, 2002

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Autoimmune Diseases, Immune Disorders

Pharmacological Actions : Apoptotic, Immunomodulatory, Immunosuppressive Agents

Additional Keywords : Dose Response

[+]

The present study provides evidence for a promising novel therapeutic strategy for the early intervention of autoimmune thyroiditis.Nov 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):4049-4054. Epub 2016 Nov 2. PMID: 28101184

Article Published Date : Nov 30, 2016

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Hashimoto's thyroiditis

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents, Interferon Gamma Reducer

[+]

Triptolide, a compound from Tripterygium wildordii, shows promise in an experimental model of Multiple Sclerosis. Aug 01, 2009

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Pubmed Data : J Med Food. 2009 Aug;12(4):714-21. PMID: 18438925

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Substances : Tripterygium wilfordii

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunosuppressive Agents

[+]

Zerumbone on the immune responses suggest that zerumbone can be a potential candidate for development of immunosuppressive agent.Jul 31, 2019

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Pubmed Data : Int Immunopharmacol. 2019 Aug ;73:552-559. Epub 2019 Jun 7. PMID: 31177081

Article Published Date : Jul 31, 2019

Study Type : Animal Study

Additional Links

Substances : Zerumbone

Pharmacological Actions : Immunosuppressive Agents

[+]

A review of the pharmacokinetics and pharmacodynamics of cannabinoids.Dec 31, 2002

Click here to read the entire abstract

Pubmed Data : Clin Pharmacokinet. 2003 ;42(4):327-60. PMID: 12648025

Article Published Date : Dec 31, 2002

Study Type : Review

Additional Links

Substances : Cannabidiol, Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Cancers: All

Pharmacological Actions : Analgesics, Apoptotic, Immunosuppressive Agents, Neuroprotective Agents

Additional Keywords : Phytotherapy

[+]

Anticellular and immunosuppressive properties of ethanolic extract of Acorus calamus rhizome.Dec 31, 2002

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2003 Jan ;3(1):53-61. PMID: 12538034

Article Published Date : Dec 31, 2002

Study Type : In Vitro Study

Additional Links

Substances : Acorus calamus

Diseases : Alcohol Toxicity

Pharmacological Actions : Immunosuppressive Agents

Additional Keywords : Plant Extracts

[+]

Antidepressant and immunosuppressive activities of two polysaccharides from Poria cocos.Nov 30, 2018

Click here to read the entire abstract

Pubmed Data : Int J Biol Macromol. 2018 Dec ;120(Pt B):1696-1704. Epub 2018 Sep 26. PMID: 30267822

Article Published Date : Nov 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Poria cocos

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Immunosuppressive Agents, Neuroprotective Agents

[+]

Baicalin suppresses type 2 immunity through breaking off the interplay between mast cell and airway epithelial cell.Feb 28, 2021

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2021 Mar 1 ;267:113492. Epub 2020 Oct 19. PMID: 33091489

Article Published Date : Feb 28, 2021

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Asthma

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

[+]

Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation.Nov 08, 2016

Click here to read the entire abstract

Pubmed Data : Cell Immunol. 2016 Nov 9. Epub 2016 Aug 9. PMID: 27865421

Article Published Date : Nov 08, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Pharmacological Actions : Immunosuppressive Agents

[+]

Cannabis may have a therapeutic role to play in reducing inflammation and over-active immune cells in autoimmune diseases. May 18, 2009

Click here to read the entire abstract

Pubmed Data : Immunobiology. 2009 May 18; PMID: 19457575

Article Published Date : May 18, 2009

Study Type : Commentary

Additional Links

Substances : Marijuana

Diseases : Autoimmune Diseases

Pharmacological Actions : Immunosuppressive Agents

[+]

CBD treatment may ameliorate experimental autoimmune encephalomyelitis through induction of immunosuppressive myeloid-derived suppressor cells.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Immunol. 2018 ;9:1782. Epub 2018 Aug 3. PMID: 30123217

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-17 downregulation

[+]

Celastrol suppresses humoral immune responses and autoimmunity.Mar 30, 2023

Click here to read the entire abstract

Pubmed Data : Sci Immunol. 2023 Mar 31 ;8(81):eadc9324. Epub 2023 Mar 31. PMID: 37000855

Article Published Date : Mar 30, 2023

Study Type : In Vitro Study

Additional Links

Substances : Celastrol

Diseases : Arthritis, Autoimmune Diseases

Pharmacological Actions : Immunosuppressive Agents

[+]

Curcumin has profound immunosuppressive effects of potential value in organ transplantation. Oct 01, 2004

Click here to read the entire abstract

Pubmed Data : J Surg Res. 2004 Oct;121(2):171-7. PMID: 15501456

Article Published Date : Oct 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Organ Transplantation

Pharmacological Actions : Antiproliferative , Histamine H2 Antagonists, Immunosuppressive Agents, NF-kappaB Inhibitor

[+]

Curcumin may have a therapeutic role in Th1-mediated immune diseases.Sep 01, 1999

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Pubmed Data : Br J Pharmacol. 1999 Sep;128(2):380-4. PMID: 10510448

Article Published Date : Sep 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Immune Dysregulation: TH1 dominance, Lipopolysaccharide-Induced Toxicity, Listeria Infections

Pharmacological Actions : Immunomodulatory, Immunosuppressive Agents, Interleukin-4 downregulation

[+]

Curcumin may have therapeutic value in inhibiting B-Cell over-activity. Oct 01, 2009

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Pubmed Data : Phytomedicine. 2009 Oct;16(10):982-8. Epub 2009 Mar 20. PMID: 19303754

Article Published Date : Oct 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Immune Disorders: B-Cell Over-Activity

Pharmacological Actions : Antiproliferative , Immunosuppressive Agents

[+]

Curcumin prevents human dendritic cell response to immune stimulants, indicating it may have value as an immunosuppresant. Sep 26, 2008

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Pubmed Data : Biochem Biophys Res Commun. 2008 Sep 26;374(3):431-6. Epub 2008 Jul 17. PMID: 18639521

Article Published Date : Sep 26, 2008

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Autoimmune Diseases, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Immunosuppressive Agents

[+]

Echinacea purpurea can be immunostimulatory, immunosuppressive, and/or anti-inflammatory depending on the portion of the plant and extraction method.Oct 07, 2009

Click here to read the entire abstract

Pubmed Data : J Neurosci Res. 2009 Oct 7. PMID: 20149833

Article Published Date : Oct 07, 2009

Study Type : In Vitro Study

Additional Links

Substances : Echinacea

Pharmacological Actions : Immunomodulatory, Immunostimulatory, Immunosuppressive Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Glycyrol prevents the progression of psoriasis-like skin inflammation.Dec 10, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Dec 11 ;24(24). Epub 2023 Dec 11. PMID: 38139164

Article Published Date : Dec 10, 2023

Study Type : In Vitro Study

Additional Links

Substances : Licorice

Diseases : Inflammation, Psoriasis

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents, Interleukin-6 Downregulation

[+]

Helenalin, a compound found within Arnica, may have a role as an immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses.Sep 01, 2009

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Pubmed Data : Mol Immunol. 2009 Sep;46(15):2892-901. Epub 2009 Aug 5. PMID: 19656571

Article Published Date : Sep 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Arnica, Helenalin

Diseases : Immune Dysregulation: TH1/TH2 imbalance

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Immunosuppressive Agents, NF-kappaB Inhibitor, Proteasome Inhibitors, Tumor Suppressor Protein p53 Upregulation

[+]

Naringenin may have therapeutic value in contact hypersensitivity supression.Jun 25, 2010

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2010 Jun 25;397(2):163-9. Epub 2010 May 22. PMID: 20471963

Article Published Date : Jun 25, 2010

Study Type : In Vitro Study

Additional Links

Substances : Naringenin

Diseases : Hypersensitivity, Hypersensitivity: Immediate

Pharmacological Actions : Antioxidants, Apoptotic, Immunosuppressive Agents

[+]

Piperlongumine may act as a promising agent for therapeutic immunosuppression.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Immunol. 2020 ;11:1172. Epub 2020 Jun 12. PMID: 32595640

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Piperlongumine

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents

[+]

Prunella vulgaris L: Critical pharmacological, expository traditional uses and extensive phytochemistry.Feb 02, 2021

Click here to read the entire abstract

Pubmed Data : Curr Drug Discov Technol. 2021 Feb 3. Epub 2021 Feb 3. PMID: 33538676

Article Published Date : Feb 02, 2021

Study Type : Review

Additional Links

Substances : Prunella vulgaris

Diseases : Cancers: All, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Cardioprotective, Immunosuppressive Agents

[+]

Quercetin's immunosuppressive action on dendritic cell activation function indicate it may play a therapeutic role in autoimmune, hypersensitivity, and/or organ transplantation.Jun 15, 2010

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Pubmed Data : J Immunol. 2010 Jun 15;184(12):6815-21. Epub 2010 May 17. PMID: 20483746

Article Published Date : Jun 15, 2010

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Autoimmune Diseases, Hypersensitivity, Organ Transplantation

Pharmacological Actions : Immunomodulatory, Immunosuppressive Agents

[+]

Resveratrol has immunomodulatory activity that may be useful for autoimmune conditions such as MS. Mar 01, 2011

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2011 Mar;11(3):310-8. Epub 2010 Aug 12. PMID: 20708723

Article Published Date : Mar 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Autoimmune Diseases, Multiple Sclerosis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents

[+]

Resveratrol has tolerogenic properties in dendritic cells.Apr 01, 2010

Click here to read the entire abstract

Pubmed Data : Immunology. 2010 Apr;129(4):525-35. Epub 2009 Nov 25. PMID: 20002210

Article Published Date : Apr 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol, Stilbenes

Diseases : Autoimmune Diseases

Pharmacological Actions : Antiproliferative , Immunosuppressive Agents, Interleukin-10 downregulation, NF-kappaB Inhibitor

[+]

The experimental evidence reviewed in this article argues in favor of the therapeutic potential of these compounds in immune disorders and cancer.Jan 31, 2002

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Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):319-32. PMID: 12052046

Article Published Date : Jan 31, 2002

Study Type : Review

Additional Links

Substances : Cannabinoids , Endocannabinoids

Diseases : Cancers: All, Endocannabinoid System, Immune Disorders

Pharmacological Actions : Antiproliferative , Apoptotic, Immunosuppressive Agents

Additional Keywords : Cannabinoid Receptors

[+]

The results demonstrate that phloretin might be developed into a new immuosuppressive treatment.Apr 30, 2009

Click here to read the entire abstract

Pubmed Data : Yao Xue Xue Bao. 2009 May ;44(5):480-5. PMID: 19618722

Article Published Date : Apr 30, 2009

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

[+]

Tripterygium wilfordii may contribute to a reduction in autoimmunity in diseases like Multiple Sclerosis. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Yao Xue Xue Bao. 2008 Dec;43(12):1179-85. PMID: 19244746

Article Published Date : Dec 01, 2008

Study Type : Commentary

Additional Links

Substances : Tripterygium wilfordii

Diseases : Autoimmune Diseases, Multiple Sclerosis

Pharmacological Actions : Immunosuppressive Agents

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View the Evidence: 52 Abstracts with Immunosuppressive Agents Research

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Immunosuppressive effects of two probiotics, Lactobacillus paracasei DSM 13434 and Lactobacillus plantarum DSM 15312.Feb 19, 2023

These results reveal an immunosuppressive effect of cannabinoid preparations.Dec 31, 2016

Chrysin ameliorated experimental autoimmune encephalomyelitis, an animal model of MS, by reducing CNS inflammation and demyelination.Nov 14, 2015

Vitamin K2 immunosuppressive effect on pediatric patients with atopic dermatitis.Nov 30, 2019

Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum.May 31, 2003

Alcohol may contribute to Klebsiella pneumoniae infection by down-regulating interleukin-17. Jun 01, 2001

An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells.Aug 30, 2011

Arctigenin could be a powerful drug candidate for acute hepatitis through immune suppression.Mar 22, 2018

Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.Oct 05, 2015

Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.Aug 14, 2000

Curcumin appears to have therapeutic value as an immunosuppressive/anti-rejection agent.Jun 01, 2010

Curcumin has a novel synergistic effect with the drug cyclosporine as an immunosuppressive. Jun 01, 2003

Curcumin has variable immunomodulatory effects.Jan 01, 2005

Geraniol represents a valuable asset against colitis alone or in combination with the conventional anti-colitic therapies.Aug 31, 2015

Immunomodulatory effect of Cynara scolymus (artichoke) in rats.Oct 23, 2018

Immunosuppression by piperine as a regulator of the NLRP3 inflammasome.Jan 31, 2022

Immunosuppressive effect of sinomenine in an allergic rhinitis mouse model.Apr 30, 2017

Immunosuppressive effects of Annona muricata leaf extract on cellular and humoral immune responses.Dec 31, 2022

Isogarcinol is a promising immunosuppressive agent for treating psoriasis.Jan 31, 2017

Modulation of gut microbiota mediates berberine-induced expansion of immuno-suppressive cells to against alcoholic liver disease.Jul 31, 2020

Mugwort (Artemisa vulgaris) demonstrates immunosuppressive activity which may be beneficial in the treatment of autoimmune diseases. Jan 01, 2009

Paeoniflorin attenuates the allergic contact dermatitis response.May 05, 2021

Poria cocos bark extract has potential as an oral immune suppressor for the treatment of atopic dermatitis and food allergy.Dec 31, 2015

T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis.Sep 30, 2017

The current study clearly demonstrates that exposure to THC leads to suppression of the immune response.Jul 31, 2002

The present study provides evidence for a promising novel therapeutic strategy for the early intervention of autoimmune thyroiditis.Nov 30, 2016

Triptolide, a compound from Tripterygium wildordii, shows promise in an experimental model of Multiple Sclerosis. Aug 01, 2009

Zerumbone on the immune responses suggest that zerumbone can be a potential candidate for development of immunosuppressive agent.Jul 31, 2019

A review of the pharmacokinetics and pharmacodynamics of cannabinoids.Dec 31, 2002

Anticellular and immunosuppressive properties of ethanolic extract of Acorus calamus rhizome.Dec 31, 2002

Antidepressant and immunosuppressive activities of two polysaccharides from Poria cocos.Nov 30, 2018

Baicalin suppresses type 2 immunity through breaking off the interplay between mast cell and airway epithelial cell.Feb 28, 2021

Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation.Nov 08, 2016

Cannabis may have a therapeutic role to play in reducing inflammation and over-active immune cells in autoimmune diseases. May 18, 2009

CBD treatment may ameliorate experimental autoimmune encephalomyelitis through induction of immunosuppressive myeloid-derived suppressor cells.Dec 31, 2017

Celastrol suppresses humoral immune responses and autoimmunity.Mar 30, 2023

Curcumin has profound immunosuppressive effects of potential value in organ transplantation. Oct 01, 2004

Curcumin may have a therapeutic role in Th1-mediated immune diseases.Sep 01, 1999

Curcumin may have therapeutic value in inhibiting B-Cell over-activity. Oct 01, 2009

Curcumin prevents human dendritic cell response to immune stimulants, indicating it may have value as an immunosuppresant. Sep 26, 2008

Echinacea purpurea can be immunostimulatory, immunosuppressive, and/or anti-inflammatory depending on the portion of the plant and extraction method.Oct 07, 2009

Glycyrol prevents the progression of psoriasis-like skin inflammation.Dec 10, 2023

Helenalin, a compound found within Arnica, may have a role as an immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses.Sep 01, 2009

Naringenin may have therapeutic value in contact hypersensitivity supression.Jun 25, 2010

Piperlongumine may act as a promising agent for therapeutic immunosuppression.Dec 31, 2019

Prunella vulgaris L: Critical pharmacological, expository traditional uses and extensive phytochemistry.Feb 02, 2021

Quercetin's immunosuppressive action on dendritic cell activation function indicate it may play a therapeutic role in autoimmune, hypersensitivity, and/or organ transplantation.Jun 15, 2010

Resveratrol has immunomodulatory activity that may be useful for autoimmune conditions such as MS. Mar 01, 2011

Resveratrol has tolerogenic properties in dendritic cells.Apr 01, 2010

The experimental evidence reviewed in this article argues in favor of the therapeutic potential of these compounds in immune disorders and cancer.Jan 31, 2002

The results demonstrate that phloretin might be developed into a new immuosuppressive treatment.Apr 30, 2009

Tripterygium wilfordii may contribute to a reduction in autoimmunity in diseases like Multiple Sclerosis. Dec 01, 2008

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Immunosuppressive Agents

View the Evidence:
52 Abstracts with Immunosuppressive Agents Research