Insulin-releasing

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71 Substances Researched for Insulin-releasing
NameACCKFocus
Apple Cider Vinegar120Locked
Green Coffee Bean120Locked
Bitter Melon414Locked
Moringa oleifera212Locked
Probiotics212Locked
Polyphenols211Locked
Lactobacillus reuteri110Locked
Nicotinamide Mononucleotide110Locked
Raspberry110Locked
Coffee34Locked
Coriandrum sativum24Locked
Ginger24Locked
Nigella sativa (aka Black Seed)24Locked
Palash24Locked
Cafestol23Locked
Flavonoids23Locked
Gallic Acid23Locked
Acorus calamus12Locked
Agrimony12Locked
Andrographolide12Locked
Asiatic Acid12Locked
Beta-Caryophyllene12Locked
Chamomile12Locked
Chicory12Locked
Citrus naringin12Locked
Corn: Purple12Locked
Curcumin12Locked
Diosmin 12Locked
Eriodictyol12Locked
Eugenol12Locked
Fenugreek12Locked
Fucoidan12Locked
Fucoxanthin 12Locked
Garlic12Locked
Gotu Kola12Locked
Gymnema Sylvestre12Locked
Hydrogen Water12Locked
Lactobacillus gasseri12Locked
Lotus 22Locked
Mulberry12Locked
Myrrh22Locked
Noni12Locked
Phellinus Linteus12Locked
Sesamin12Locked
Stevia12Locked
Terminalia12Locked
Thymoquinone12Locked
Ursolic Acid12Locked
Andrographis11Locked
Antrodia camphorata11Locked
Apricot11Locked
Banaba11Locked
Basil11Locked
Berberine11Locked
Blackberries11Locked
Caffeic Acid11Locked
Carnitine11Locked
Cocoa11Locked
Eggplant11Locked
Fig11Locked
Ginseng (American)11Locked
Grapes11Locked
Green Tea11Locked
Hydroxytyrosol11Locked
Mangiferin11Locked
Mistletoe11Locked
Myricetin11Locked
Nettle11Locked
Purslane11Locked
Resveratrol11Locked
Scopoletin11Locked

View the Evidence:
75 Abstracts with Insulin-releasing Research

[+]

Apple cider vinegar had positive effects on FBS and HbA1c in T2DM patients.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2025 ;12:1528383. Epub 2025 Jan 30. PMID: 39949546
Article Published Date : Dec 31, 2024
Study Type : Meta Analysis
Additional Links
Substances : Apple Cider Vinegar
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

The influence of green coffee bean extract supplementation on blood glucose levels.Mar 10, 2020

Pubmed Data : Phytother Res. 2020 Mar 11. Epub 2020 Mar 11. PMID: 32159261
Article Published Date : Mar 10, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Green Coffee Bean
Diseases : Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Effects of red raspberry polyphenols and metabolites on the biomarkers of inflammation and insulin resistance in type 2 diabetes.May 09, 2022

Pubmed Data : Food Funct. 2022 May 10 ;13(9):5166-5176. Epub 2022 May 10. PMID: 35421887
Article Published Date : May 09, 2022
Study Type : Human Study
Additional Links
Substances : Polyphenols, Raspberry
Diseases : Diabetes Mellitus: Type 2, Inflammation, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Insulin-releasing
[+]

Enrichment of gut microbiota with lactobacillus reuteri increases insulin secretionJun 16, 2015

Pubmed Data : Diabetes Care. 2015 Jun 17. Epub 2015 Jun 17. PMID: 26084343
Article Published Date : Jun 16, 2015
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri, Probiotics
Diseases : Insulin: Low
Pharmacological Actions : Insulin-releasing
Additional Keywords : Microbiota
[+]

Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus.Feb 11, 2018

Pubmed Data : J Med Food. 2018 Feb 12. Epub 2018 Feb 12. PMID: 29431598
Article Published Date : Feb 11, 2018
Study Type : Human Study
Additional Links
Substances : Bitter Melon
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Moringa oleifera leaf may be a potential agent in the treatment of type 2 diabetes.Feb 29, 2016

Pubmed Data : J Med Assoc Thai. 2016 Mar ;99(3):308-13. PMID: 27276742
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Moringa oleifera
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Oral administration of NMN elevates plasma levels of NMN and NAD+, and postprandial serum insulin levels.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Nutr ESPEN. 2023 Aug ;56:83-86. Epub 2023 May 5. PMID: 37344088
Article Published Date : Jul 31, 2023
Study Type : Human Study
Additional Links
Substances : Nicotinamide Mononucleotide
Diseases : Aging
Pharmacological Actions : Insulin-releasing
[+]

Acorus calamus has insulin releasing and alpha-glucosidase inhibitory activity, confirming its traditional use in American and Indonesia for diabetes. Jan 04, 2010

Pubmed Data : J Ethnopharmacol. 2010 Jan 4. Epub 2010 Jan 4. PMID: 20051258
Article Published Date : Jan 04, 2010
Study Type : Animal Study
Additional Links
Substances : Acorus calamus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Alpha-glucosidase inhibitor , Insulin-releasing
Additional Keywords : Science Confirms Tradition
[+]

Agrimony exhibits antihyperglycaemic, insulin-releasing and insulin-like activity. Jul 01, 1998

Pubmed Data : Br J Nutr. 1998 Jul;80(1):109-14. PMID: 9797650
Article Published Date : Jul 01, 1998
Study Type : Animal Study
Additional Links
Substances : Agrimony
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents, Insulin-mimetic, Insulin-releasing
[+]

Anthocyanin-rich purple corn extract exerted anti-diabetic effects through protection of pancreatic β-cells and increase of insulin secretion.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2015 Feb ;9(1):22-9. Epub 2015 Jan 28. PMID: 25671064
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Corn: Purple
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
[+]

Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats.Dec 31, 2003

Pubmed Data : J Pharm Pharmacol. 2004 Jan ;56(1):101-5. PMID: 14980006
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Diabetes Mellitus: Type 1: Prevention, Hypertension
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Phytotherapy
Problem Substances : Insulin
[+]

Asiatic acid improves insulin secretion of β cells in type 2 diabetes through TNF- α/Mfn2 pathway.Apr 24, 2023

Pubmed Data : Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Apr 25 ;52(2):185-194. PMID: 37283103
Article Published Date : Apr 24, 2023
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
[+]

Bitter melon fruit bioactives charantin and vicine potential for diabetes prophylaxis and treatment. Apr 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Apr 8 ;10(4). Epub 2021 Apr 8. PMID: 33918062
Article Published Date : Apr 07, 2021
Study Type : Animal Study
Additional Links
Substances : Bitter Melon
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing, Prophylactic Agents
[+]

Black seed thymoquinone improved insulin secretion, hepatic glycogen storage, and oxidative stress in streptozotocin-induced diabetic male wistar rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8104165. Epub 2018 Mar 4. PMID: 29686746
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Insulin-releasing
[+]

Butea monosperma extract significantly reduced blood glucose by 40% and increased plasma insulin levels by 37% in diabetic rats.Jul 31, 2014

Pubmed Data : Pharm Biol. 2014 Aug ;52(8):1021-7. Epub 2014 Mar 12. PMID: 24617860
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Palash
Diseases : Diabetic Complications, Dyslipidemias
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Cafestol may contribute to the reduced risk of developing type-2 diabetes in coffee consumers.Jul 31, 2017

Pubmed Data : J Nat Prod. 2017 Aug 1. Epub 2017 Aug 1. PMID: 28763212
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cafestol, Coffee
Diseases : Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Risk Reduction
[+]

Chicoric acid exhibits antidiabetic action throug enhancing insulin release and glucose intake.Dec 05, 2008

Pubmed Data : Biochem Biophys Res Commun. 2008 Dec 5;377(1):131-5. Epub 2008 Oct 1. PMID: 18834859
Article Published Date : Dec 05, 2008
Study Type : Animal Study
Additional Links
Substances : Chicory
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Coriadium sativum has antihyperglycaemic, insulin-releasing and insulin-like activity. Mar 01, 1999

Pubmed Data : Br J Nutr. 1999 Mar;81(3):203-9. PMID: 10434846
Article Published Date : Mar 01, 1999
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia
Pharmacological Actions : Insulin-mimetic, Insulin-releasing, Insulinotrophic
[+]

Coriander seed may stimulate insulin release from pancreatic beta cells in a type 1 diabetic rat model.Mar 01, 2009

Pubmed Data : Phytother Res. 2009 Mar;23(3):404-6. PMID: 19003941
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing, Insulinotrophic
Additional Keywords : Plant Extracts
[+]

Curcumin has an insulin releasing effect in rat-isolated pancreatic islets.Aug 01, 2010

Pubmed Data : Angiology. 2010 Aug;61(6):557-66. Epub 2010 Apr 14. PMID: 20395228
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetes Mellitus: Type 1, Insulin: Low
Pharmacological Actions : Insulin-releasing
[+]

Didymin protects pancreatic beta cells by enhancing mitochondrial function in high-fat diet-induced impaired glucose tolerance.Jan 02, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetol Metab Syndr. 2024 Jan 3 ;16(1):7. Epub 2024 Jan 3. PMID: 38172956
Article Published Date : Jan 02, 2024
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Diabetes Mellitus: Type 2, High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Insulin-releasing, Pancreato Protective Agents
[+]

Dietary garlic and especially ginger have anti-diabetic effects. Mar 01, 2008

Pubmed Data : J Med Food. 2008 Mar;11(1):152-9. PMID: 18361751
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Garlic, Ginger
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Insulinotrophic
[+]

Diosmin potentiates the antidiabetic effects of linagliptin.Apr 28, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2025 Apr 29 ;18(5). Epub 2025 Apr 29. PMID: 40430475
Article Published Date : Apr 28, 2025
Study Type : Animal Study
Additional Links
Substances : Diosmin
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing, Renoprotective
[+]

Dual actions of gallic acid and andrographolide trigger AdipoR1 to stimulate insulin secretion in a streptozotocin-induced diabetes rat model.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2023 Jan ;13(1):11-19. Epub 2022 Sep 28. PMID: 36685073
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Andrographolide, Gallic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
[+]

Effect of fucoxanthin on metabolic syndrome, insulin sensitivity, and insulin secretion.Jun 30, 2023

Pubmed Data : J Med Food. 2023 Jul ;26(7):521-527. Epub 2023 Jul 4. PMID: 37405785
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Effect of β-Caryophyllene on insulin resistance in skeletal muscle of high fat diet and fructose-induced type-2 diabetes.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinformation. 2021 ;17(8):741-747. Epub 2021 Aug 31. PMID: 35540699
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Diabetes Mellitus: Type 2, High Fat Diet
Pharmacological Actions : Insulin-releasing, MicroRNA modulator
[+]

Eriodictyol stimulates insulin secretion.Feb 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Feb 5 ;820:245-255. Epub 2017 Dec 8. PMID: 29229531
Article Published Date : Feb 04, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Eugenol improves insulin secretion and content of pancreatic islets from male mouse.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Endocrinol. 2020 ;2020:7416529. Epub 2020 Aug 5. PMID: 32831835
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
[+]

Exploring the therapeutic potential of Terminalia chebula Retz. in alleviating the complications of letrozole-induced PCOS.Feb 28, 2025

Pubmed Data : Reprod Sci. 2025 Mar ;32(3):836-853. Epub 2025 Feb 12. PMID: 39939489
Article Published Date : Feb 28, 2025
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Fucoidan may stimulate insulin secretion and provide pancreatic protection via the cAMP signaling pathway, in vivo and in vitro.Aug 31, 2015

Pubmed Data : Mol Med Rep. 2015 Sep ;12(3):4501-7. Epub 2015 Jun 23. PMID: 26130492
Article Published Date : Aug 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Pancreatic Diseases
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Dose Response
[+]

Gymnena sylvestre stimulates insulin release.Nov 01, 1999

Pubmed Data : J Endocrinol. 1999 Nov;163(2):207-12. PMID: 10556769
Article Published Date : Nov 01, 1999
Study Type : Animal Study
Additional Links
Substances : Gymnema Sylvestre
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
[+]

Naringin was found to be an effective antidiabetic agent which increased Insulin gene expression and insulin secretion.Dec 31, 2017

Pubmed Data : Cells Tissues Organs. 2018 ;206(3):133-143. Epub 2019 Mar 18. PMID: 30884485
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin-releasing
Additional Keywords : Gene Expression Regulation
[+]

Nigella sativa stimulate insulin secretion from isolated rat islets and inhibit the digestion and absorption of (CH2O)n in the gut.Aug 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31375555
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Noni fruit juice prevents ischemic neuronal damage through suppression of the development of post-ischemic glucose intolerance.Oct 01, 2010

Pubmed Data : J Nat Med. 2010 Oct;64(4):468-73. Epub 2010 Jun 24. PMID: 20574728
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Insulin-releasing, Neuroprotective Agents
[+]

Phellinus linteus extracts could significantly decrease serum glucose concentration and increases insulin secretion in the islets of Langerhans.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(4):301-11. PMID: 27481296
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Phellinus Linteus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Probiotic Lactobacillus gasseri SBT2055 improves insulin secretion in a diabetic rat model.Jan 31, 2019

Pubmed Data : J Dairy Sci. 2019 Feb ;102(2):997-1006. Epub 2018 Nov 22. PMID: 30471910
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri, Probiotics
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Standardized Mori ramulus extract improves insulin secretion and insulin sensitivity in C57BLKS/J db/db mice and INS-1 cells.Jul 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug ;92:308-315. Epub 2017 May 25. PMID: 28551552
Article Published Date : Jul 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mulberry
Diseases : Insulin Resistance
Pharmacological Actions : Anti-Glycation Agents, Antioxidants, Insulin-releasing, Insulin Sensitizers
Additional Keywords : Plant Extracts
[+]

Stevia contains compounds which enhance the insulin secretion of beta cells. Feb 01, 2000

Pubmed Data : Metabolism. 2000 Feb;49(2):208-14. PMID: 10690946
Article Published Date : Feb 01, 2000
Study Type : Animal Study
Additional Links
Substances : Stevia
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
[+]

The antihyperglycemic activity of B. monosperma was mediated by enhanced insulin secretion and enhanced glycogen formation in the liver.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:356290. Epub 2014 Mar 31. PMID: 24860609
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Palash
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

The combination treatment with ursolic acid and rosiglitazone ameliorated HFD-induced glucose intolerance and insulin resistance.May 31, 2016

Pubmed Data : J Physiol Biochem. 2016 Jun ;72(2):345-52. Epub 2016 Apr 18. PMID: 27090933
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : High Fat Diet, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

The effects of photobiomodulation therapy on porcine islet insulin secretion.May 31, 2022

Pubmed Data : Photobiomodul Photomed Laser Surg. 2022 Jun ;40(6):395-401. Epub 2022 May 20. PMID: 35594334
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 1
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Insulin-releasing
[+]

The improvement of insulin level after hydrogen-rich water therapy in streptozotocin-induced diabetic rats.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2022 Jan ;15(1):182-187. Epub 2022 Jan 28. PMID: 35369585
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Insulin-releasing, Superoxide Dismutase Up-regulation
[+]

These findings prove sesamin's efficacy in ameliorating the symptoms of diabetes through its potent pharmacological activities.Oct 24, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Oct 25 ;28(21). Epub 2023 Oct 25. PMID: 37959677
Article Published Date : Oct 24, 2023
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Hypoglycemic Agents, Insulin-releasing, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

These results showed that hypoglycemic effects of MOLE might be mediated through the stimulation of insulin release leading to enhanced glucose uptake and glycogen synthesis.Jun 26, 2015

Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 Jun 27. Epub 2015 Jun 27. PMID: 26124050
Article Published Date : Jun 26, 2015
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Diabetes Mellitus: Type 2, Hypoglycemia
Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Metformin
[+]

This study has provided evidence that clearly supported the traditional use of Goto Kola as a remedy for diabetes.Jan 12, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jan 13. Epub 2016 Jan 13. PMID: 26775274
Article Published Date : Jan 12, 2016
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Together these data demonstrated chamomile oil along with in vivo-differentiated stem cell is a promising new treatment for diabetes.May 31, 2020

Pubmed Data : J Diabetes Metab Disord. 2020 Jun ;19(1):453-460. Epub 2020 May 11. PMID: 32550197
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Insulin-releasing
[+]

Trigonelline inhibits caspase 3 to protect β cells apoptosis in streptozotocin-induced type 1 diabetic mice.Oct 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Oct 5 ;836:115-121. Epub 2018 Aug 18. PMID: 30130525
Article Published Date : Oct 04, 2018
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Insulin-releasing, Interleukin-6 Downregulation, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A Portulaca oleracea L. extract promotes insulin secretion.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2018 Jun ;12(3):183-190. Epub 2018 Apr 25. PMID: 29854323
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Purslane
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Dose Response
[+]

A review of the effects of Urtica dioica (nettle) in metabolic syndrome.Apr 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2022 May ;25(5):543-553. PMID: 35911652
Article Published Date : Apr 30, 2022
Study Type : Review
Additional Links
Substances : Nettle
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Insulin-releasing
[+]

A. camphorata might have anti-diabetic effects and could be a novel treatment for T2DM.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:67. Epub 2016 Mar 21. PMID: 27047382
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Advances in the pharmacological effects and mechanisms of Nelumbo nucifera gaertn. Extract nuciferine.Sep 14, 2024

Pubmed Data : J Ethnopharmacol. 2024 Sep 15 ;331:118262. Epub 2024 Apr 24. PMID: 38670406
Article Published Date : Sep 14, 2024
Study Type : Review
Additional Links
Substances : Lotus
Diseases : HIV Infections, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antimicrobial, Antioxidants, Antiviral Agents, Hypolipidemic, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

American Ginseng Stimulates Insulin Production and Prevents Beta Cell Death. Sep 01, 2006

Pubmed Data : Evid Based Complement Alternat Med. 2006 Sep;3(3):365-72. PMID: 16951721
Article Published Date : Sep 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Ginseng (American)
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Protection
[+]

Andrographis exhibits insulin-releasing cells in vitro.Apr 01, 2008

Pubmed Data : Acta Med Indones. 2008 Apr-Jun;40(2):63-8. PMID: 18560025
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
[+]

Berberine potentiates insulin secretion and prevents β-cell dysfunction through the miR-204/SIRT1 signaling pathway.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:720866. Epub 2021 Sep 22. PMID: 34630099
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing, MicroRNA modulator, Pancreato Protective Agents
[+]

Cafestol may contribute to the preventive effects on T2D in coffee drinkers and be of therapeutic interest.Oct 22, 2015

Pubmed Data : J Nat Prod. 2015 Oct 23 ;78(10):2447-51. Epub 2015 Oct 14. PMID: 26465380
Article Published Date : Oct 22, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cafestol, Caffeic Acid, Coffee
Diseases : Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Insulin-releasing
Additional Keywords : Risk Reduction
[+]

Commiphora myrrha stimulates insulin secretion from β-cells.Feb 09, 2023

Pubmed Data : J Ethnopharmacol. 2023 Feb 10 ;302(Pt B):115937. Epub 2022 Nov 19. PMID: 36410575
Article Published Date : Feb 09, 2023
Study Type : In Vitro Study
Additional Links
Substances : Myrrh
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
[+]

Effect of low-level laser irradiation on in vitro function of pancreatic islets.Nov 30, 2009

Pubmed Data : Transplant Proc. 2009 Dec ;41(10):4313-5. PMID: 20005390
Article Published Date : Nov 30, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
Problem Substances : Insulin
[+]

Effects of carnitine supplementation on glycemic markers in women with overweight and obesity.Oct 30, 2025

Pubmed Data : Diabetes Res Clin Pract. 2025 Oct 31 ;230:112981. Epub 2025 Oct 31. PMID: 41177307
Article Published Date : Oct 30, 2025
Study Type : Review
Additional Links
Substances : Carnitine
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing, Insulin Sensitizers
[+]

Epicatechin flavanoid compound cause beta cell regeneration. - Article 2Mar 01, 1984

Pubmed Data : Diabetes. 1984 Mar;33(3):291-6. PMID: 6365662
Article Published Date : Mar 01, 1984
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Regeneration
[+]

Gallic acid preserves beta cell function and exhibits insulin-secreting action. Jul 16, 2009

Pubmed Data : Phytother Res. 2009 Jul 16. PMID: 19610036
Article Published Date : Jul 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Regeneration
[+]

Lagerstroemia speciosa leaves were effective in the treatment of diabetes.Apr 30, 2013

Pubmed Data : Mol Med Rep. 2013 May ;7(5):1607-12. Epub 2013 Mar 26. PMID: 23545843
Article Published Date : Apr 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Banaba
Diseases : Diabetes Mellitus: Type 1, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective, Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Low-carbohydrate diets in the management of obesity and type 2 diabetes.Apr 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Apr 8 ;17(7). Epub 2020 Apr 8. PMID: 32276484
Article Published Date : Apr 07, 2020
Study Type : Review
Additional Links
Diseases : Diabetes Mellitus: Type 2, Obesity
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Hepatoprotective, Insulin-releasing, Insulin Sensitizers
Additional Keywords : Anti-Obesity Agents
[+]

Mangiferin, a potential supplement to improve metabolic syndrome.Dec 31, 2023

Pubmed Data : Am J Chin Med. 2024 ;52(2):355-386. Epub 2024 Mar 26. PMID: 38533569
Article Published Date : Dec 31, 2023
Study Type : Review
Additional Links
Substances : Mangiferin
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Insulin-releasing
[+]

Phenolic substances from Ocimum species enhance glucose-stimulated insulin secretion.Dec 21, 2017

Pubmed Data : J Nat Prod. 2017 Dec 22 ;80(12):3267-3275. Epub 2017 Dec 1. PMID: 29192771
Article Published Date : Dec 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Basil
Diseases : Insulin Disorders
Pharmacological Actions : Insulin-releasing
Additional Keywords : Gene Expression Regulation
[+]

Resveratrol may positively modulate insulin secretion and response in beta cells. Feb 25, 2011

Pubmed Data : J Biol Chem. 2011 Feb 25;286(8):6049-60. Epub 2010 Dec 16. PMID: 21163946
Article Published Date : Feb 25, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Blood Sugar Problems, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Saponins of Momordica charantia increase insulin secretion in INS-1 pancreatic β-cells.Oct 13, 2020

Pubmed Data : Endocrinol Diabetes Nutr. 2020 Oct 14. Epub 2020 Oct 14. PMID: 33069631
Article Published Date : Oct 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Bitter Melon
Diseases : Hyperglycemia
Pharmacological Actions : Insulin-releasing
[+]

Scopoletin stimulates the secretion of insulin.Aug 31, 2022

Pubmed Data : J Pharm Pharmacol. 2022 Sep 1 ;74(9):1274-1281. PMID: 35099527
Article Published Date : Aug 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Scopoletin
Diseases : Insulin Disorders
Pharmacological Actions : Insulin-releasing
[+]

The aim of this review is to report on the available anti-diabetic polyphenols, medicinal plants, fruits and vegetables and their potential in the treatment of diabetes mellitus.Nov 23, 2015

Pubmed Data : Curr Pharm Des. 2015 Nov 24. Epub 2015 Nov 24. PMID: 26601968
Article Published Date : Nov 23, 2015
Study Type : Review
Additional Links
Substances : Apricot, Blackberries, Cocoa, Coffee, Eggplant, Grapes, Green Tea, Polyphenols
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Glucose Uptake Optimization, Insulin-releasing
Additional Keywords : Risk Reduction
[+]

The antidiabetic effectiveness of momordica was compared to active treatment with several oral antidiabetic drugs and proved it had comparable effects.Dec 31, 2014

Pubmed Data : Ceska Slov Farm. 2015 ;64(4):126-32. PMID: 26459126
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Bitter Melon
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing, Insulin Sensitizers
Additional Keywords : Natural Substances Versus Drugs
[+]

The effects of hydroxytyrosol on Prdx6 and insulin expression in diabetic rat pancreases.Jul 31, 2023

Pubmed Data : Histochem Cell Biol. 2023 Aug ;160(2):127-134. Epub 2023 May 23. PMID: 37219732
Article Published Date : Jul 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Hydroxytyrosol
Diseases : Hyperglycemia
Pharmacological Actions : Antioxidants, Insulin-releasing
Problem Substances : Insulin
[+]

Therapeutic potential of multifunctional myricetin for treatment of type 2 diabetes mellitus.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2023 ;10:1175660. Epub 2023 May 26. PMID: 37305094
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Myricetin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Insulin-releasing
[+]

These data indicate that aqueous myrrh resin solution has a direct stimulatory effect on β-cells without compromising plasma membrane integrity.Aug 19, 2020

Pubmed Data : J Ethnopharmacol. 2020 Aug 20 ;264:113075. Epub 2020 Aug 20. PMID: 32829055
Article Published Date : Aug 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Myrrh
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
[+]

These results validate the traditional use of Nelumbo Nucifera leaves for the management of diabetes.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Chin Med. 2016 Feb ;36(1):71-7. PMID: 26946622
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Insulin-releasing, Interleukin-1 beta downregulation
Additional Keywords : Plant Extracts
[+]

This review summarizes the antidiabetic potentials of the genus Ficus.Jan 02, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29305899
Article Published Date : Jan 02, 2018
Study Type : Review
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Viscothionin purified from mistletoe induces insulin secretion from pancreatic beta cells.Apr 23, 2019

Pubmed Data : J Ethnopharmacol. 2019 Apr 24 ;234:172-179. Epub 2019 Jan 17. PMID: 30660712
Article Published Date : Apr 23, 2019
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe
Diseases : Diabetes Mellitus: Type 2, Hypoglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Insulin-releasing
Additional Keywords : Plant Extracts

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