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Interleukin-1 beta downregulation
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464 Substances Researched for Interleukin-1 beta downregulation
Name
AC
CK
Focus
Curcumin
51
104
Ginsenosides
53
94
Flavonoids
33
68
Berberine
33
56
Paeoniflorin
30
56
Resveratrol
26
48
Astragaloside
23
40
Astaxanthin
19
36
Polyphenols
22
36
Probiotics
6
36
Paeonol
20
35
Omega-3 Fatty Acids
5
34
Puerarin
18
34
Vitamin D
7
32
Hesperidin
15
30
Quercetin
17
29
Safflower
13
28
Ginger
14
26
Tanshinone IIA
17
26
Sulforaphane
15
25
Thymoquinone
13
24
Anthocyanins
6
23
Green Tea
9
23
Melatonin
12
23
Biochanin A
12
22
Almond
3
21
Chrysin
11
21
Fisetin
11
21
DHA (Docosahexaenoic Acid)
2
20
Luteolin
12
20
Pterostilbene
10
20
Bee Venom
6
19
Citrus naringin
13
19
Dandelion
12
19
Emodin
11
19
Fucoidan
12
19
Lycopene
11
19
Naringenin
12
19
Rose
12
19
Vitamin C
9
19
Dogwood
11
18
EGCG (Epigallocatechin gallate)
9
18
Magnolol
9
18
Patchouli
11
18
Rosmarinic acid
8
18
Honokiol
10
17
Betulinic acid
7
16
Moringa oleifera
10
16
Phloretin
7
16
Crocin
9
15
Piperine
9
15
Tangeretin
9
15
Allicin
8
14
Black Tea
4
14
Cyanidin 3-glucoside
3
14
Echinacea
3
14
Ellagic Acid
7
14
Folic Acid
3
14
Nobiletin
9
14
Sesamin
3
14
Vitamin B-6
3
14
Wogonin
9
14
Apigenin
9
13
Asiatic Acid
9
13
Gastrodin
8
13
Ginseng (Korean)
7
13
Honeysuckle
8
13
Lotus
8
13
Strawberry
3
13
FOS (Fructooligosaccharides)
2
12
Honey
2
12
Isoliquiritigenin
7
12
Lactobacillus plantarum
7
12
Lutein
2
12
Mulberry
6
12
Shikonin
6
12
Silibinin
3
12
Tart Cherry
2
12
Vitamin E
2
12
Vitexins
5
12
Burdock
6
11
Diosgenin
6
11
Formononetin
7
11
Gingerol
7
11
Gotu Kola
7
11
Kaempferol
6
11
Mangiferin
8
11
Pomegranate
6
11
Purslane
6
11
Yoghurt
2
11
Aloe Vera
5
10
Bacillus coagulans
1
10
Bilberry
1
10
Bloodroot
1
10
Breast Milk
1
10
Crocetin
6
10
Delphinidin
1
10
Eicosapentaenoic acid (EPA)
1
10
Fucoxanthin
6
10
Genipin
6
10
Guduchi
6
10
Olive
1
10
Olive leaf extract
6
10
Virgin Coconut Oil
1
10
Vitamin A
1
10
Arctigenin
5
9
Beta-Caryophyllene
5
9
Cannabidiol
6
9
Carnosic Acid
5
9
Chrysanthemum Indicum
5
9
Frankincense
6
9
Geraniol
5
9
Huperzine
5
9
Myricetin
6
9
Oleuropein
5
9
Procyanidin B2
6
9
Punicalagin
3
9
Red Sage
5
9
Celastrol
5
8
Chlorogenic Acid
4
8
Coenzyme Q10
4
8
Diosmin
5
8
Ginkgo biloba
4
8
Hydrogen Water
4
8
Ligustrazine
4
8
Lion's Mane (Hericium Erinaceus)
4
8
Lychee
4
8
Medicinal Mushrooms
5
8
Raspberry
4
8
Rutin
4
8
Sea buckthorn
5
8
Stilbenes
4
8
Turmeric
6
8
Chamomile
4
7
Fermented Foods and Beverages
4
7
Fig
2
7
Flaxseed
4
7
Grape Seed Extract
4
7
Kefir
4
7
NAC (N-acetyl-L-cysteine)
4
7
Panax Notoginseng
4
7
Selenium
4
7
Sesamol
5
7
Thymol
4
7
Whey
4
7
beta-Carotene
4
7
6-Shogaol
3
6
Agaricus Blazei
3
6
Amygdalin
3
6
Artesunate
3
6
Ashwagandha
4
6
Astragalus
3
6
Baicalein
3
6
Bitter Melon
4
6
Black Currant
3
6
Black Raspberry
4
6
Carvacrol
5
6
Chaga Mushroom (Inonotus obliquus)
3
6
Chinese Skullcap
3
6
Cordyceps Militaris
3
6
Cranberry
3
6
Eriodictyol
5
6
Eucalyptus
3
6
Ferulic acid
4
6
Ginseng
3
6
Lactobacillus probiotics
3
6
Lactobacillus reuteri
3
6
Lactoferrin
4
6
Oak
4
6
Palmitoylethanolamide
3
6
Parthenolide
4
6
Rosemaric Acid
3
6
Royal Jelly
4
6
Schisandra
3
6
Sweet Potato: Purple
3
6
Blueberry
4
5
Cinnamaldehyde
3
5
Diosmetin
1
5
Garlic
3
5
Glycyrrhizin
4
5
Hemp Seed
4
5
Isothiocyanates
3
5
Japanese cypress
3
5
Jujube
3
5
Kiwifruit
3
5
MSM (Methylsulfonylmethane)
3
5
Nigella sativa (aka Black Seed)
3
5
Oleanolic acid
3
5
Oridonin
4
5
P-Coumaric Acid
3
5
Papaya: Fermented
1
5
Peony
3
5
Plantago asiatica
3
5
Propolis: Bee
3
5
Seaweed: Brown
3
5
Urolithin A
3
5
Ursolic Acid
3
5
Xanthohumol
3
5
Alpha-Lipoic Acid
3
4
Amla Fruit
2
4
Apocynin
2
4
Artichoke
2
4
Bee Pollen
2
4
Bee Propolis
3
4
Caffeic Acid
2
4
Catechin
3
4
Chokeberry
3
4
Citral
2
4
Cordyceps sinensis
2
4
Dong Quai
2
4
Fish Oil
3
4
Genistein
2
4
Ginseng (Siberian)
2
4
Gynostemma
3
4
Hu Zhang (Polygonum cuspidatum)
2
4
Hydroxytyrosol
2
4
Lactobacillus paracasei
2
4
Lactobacillus rhamnosus
2
4
Lactobacillus rhamnosus GG
2
4
Lavender: Essential Oil
2
4
Myrrh
2
4
Oligosaccharides
2
4
Orange
2
4
Perilla
2
4
Perillaldehyde
2
4
Phyllanthus amarus
3
4
Piceatannol
2
4
Prunella vulgaris
2
4
Rosemary
2
4
Saffron
3
4
Salvia miltiorrhiza
2
4
Silymarin
2
4
Soy
3
4
Spikenard
3
4
Walnut
3
4
White Tea
2
4
Zerumbone
3
4
Antrodia camphorata
2
3
Bai Zhu
2
3
Banana
2
3
Bay Laurel
2
3
Bergamot
2
3
Bromelain
2
3
Caffeic acid phenethyl ester
2
3
Chrysanthemum Morifolium
2
3
Diallyl sulfide
2
3
Goji
2
3
Guava
2
3
Hawthorn
2
3
Licorice
3
3
Liquiritigenin
3
3
Manuka Honey
2
3
Oats
2
3
Persimmon
2
3
Red Clover
2
3
Red Marine Algae
2
3
Reishi Mushroom
2
3
Sarsaparilla
2
3
Theaflavins
2
3
Theanine
2
3
Vanillin
3
3
Zataria multiflora
2
3
18β-Glycyrrhetinic Acid
1
2
Acai
1
2
Adlay
1
2
Alpha Linolenic Acid
1
2
Amygdalin (laetrile)
2
2
Anemarrhena asphodeloides
1
2
Apple Cider Vinegar
1
2
Apples
1
2
Arginine
1
2
Arugula
1
2
Aspen
1
2
Avocado
2
2
Bael
1
2
Bamboo
1
2
Barley
1
2
Basil: Sweet
2
2
Beans: All
1
2
Beet
1
2
Benzyl isothiocyanate
2
2
Bifidobacterium
1
2
Bifidobacterium Bifidum
1
2
Bifidobacterium Lactis
1
2
Billygoat Weed
1
2
Bitter Orange
2
2
Blue Honeysuckle
1
2
Boron
1
2
Brown Rice
1
2
Brown Rice: Pre-Germinated
1
2
Bufalin
1
2
Cabbage
1
2
Camel Milk
1
2
Cannabigerol
1
2
Cannabinoids
1
2
Cannabis
1
2
Carnosine
1
2
Carnosol
1
2
Chaenomeles speciosa
1
2
Cherry: All Varieties
2
2
Chia
1
2
Chlorella (Algae)
1
2
Citrus Oils
1
2
Citrus Peel
1
2
Coconut Oil
1
2
Combretum fragrans
1
2
Common bean
1
2
Corn: Purple
1
2
Cucurbitacin E
2
2
Curry Tree
1
2
Cystine
1
2
Daidzein
1
2
EPA (Eicosapentaenoic Acid)
1
2
Elm tree
1
2
Essential Oils: Unspecified
1
2
Flavan-3-ols
1
2
Gallic Acid
1
2
Garcinia Mangostana
1
2
Gardenia
1
2
Ginseng (American)
1
2
Glycyrrhiza uralensis
2
2
Gold (nanoparticles)
1
2
Grape
1
2
Helenalin
1
2
Hibiscus
2
2
Hibiscus sabdariffa
1
2
Honeydew (melon)
1
2
Hops
1
2
Horsetail
1
2
Indole-3-Carbinol
1
2
Isoflavones
1
2
Japanese mugwort
1
2
Kaempferia parviflora
1
2
Krill
1
2
Kudzu
1
2
Lactobacillus Acidophilus
1
2
Lactobacillus Brevis
1
2
Lactobacillus fermentum
1
2
Lactobacillus sakei
1
2
Lactobacillus salivarius
1
2
Loquat
1
2
Lupeol
1
2
Magnesium
1
2
Magnolia
1
2
Mango
1
2
Maqui
1
2
Marigold
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Neem
1
2
Nettle
1
2
Oligonol
1
2
Oolong tea
1
2
Orange: Mandarin
1
2
Orthosiphon
1
2
Oyster Mushroom: Indian
1
2
Passion Flower
1
2
Peanut
1
2
Pectin
1
2
Peppermint
1
2
Phellinus Linteus
2
2
Phlorotannins
1
2
Phyllanthus emblica
1
2
Pine Needle
2
2
Pine Nut
1
2
Pipsisssewa
1
2
Porridge
1
2
Propolis: Brazillian
1
2
Psychedelics:All
1
2
Pulsatilla pratensis
1
2
Pumpkin Seeds
1
2
Pycnogenol (Pine Bark)
1
2
Quince
1
2
Radish
1
2
Rubia Cordifolia
1
2
Safranal
1
2
Shiitake Mushroom
1
2
Sour Cherry
2
2
Spirulina
1
2
St. Johns Wort
1
2
Stevia
1
2
Suma (Pfaffia Paniculata)
1
2
Sweet Lime
1
2
Tannic Acid
1
2
Tetrahydrocurcumin
1
2
Thyme
2
2
Tomatidine
1
2
Toona sinensis
1
2
Unsaponifiables
2
2
Vitamin B-12
1
2
Vitamin E: alpha tocopherol
1
2
Water: Deuterium Depleted
1
2
Wheat Bran
1
2
Wheat Germ
1
2
Xanthones
1
2
Yarrow
1
2
Yellow Tea
1
2
Yerba Mate
1
2
Zeaxanthin
1
2
Achillea fragrantissima
1
1
Agrimony
1
1
Alpha-Carotene
1
1
Angelica
1
1
Apple Polyphenols
1
1
Ayahuasca
1
1
Babchi
1
1
Beta Sitosterol
1
1
Beta-Elemene
1
1
Black Pepper
1
1
Blackberry
1
1
Boneset
1
1
Carotenoids
1
1
Chicory
1
1
Coconut
1
1
Coriandrum sativum
1
1
Coriolus versicolor
1
1
Corn Silk
1
1
Cryptomeria japonica
1
1
Cryptoxanthin
1
1
Cucurbitacin B
1
1
Damnacanthal
1
1
Delta-tetrahydrocannabinol (THC)
1
1
Dill
1
1
Eugenol
1
1
Evening Primrose Oil
1
1
Fruit: All
1
1
Galactooligosaccharides
1
1
Hazelnut
1
1
Hemp Protein
1
1
Juniper
1
1
Kimchi
1
1
Lactobacillus gasseri
1
1
Lupine
1
1
Macadamia
1
1
Maple
1
1
Meadowsweet
1
1
Mushrooms: All
1
1
Nuts
1
1
Oleocanthal
1
1
Oregano
1
1
Palash
1
1
Panax Ginseng
1
1
Pistachio nut
1
1
Plantago
1
1
Pomegranate flower
1
1
Poria cocos
1
1
Prebiotics
1
1
Purple Carrots
1
1
Rhubarb
1
1
Riboflavin (Vitamin B-2)
1
1
Rice Bran
1
1
Sage
1
1
Salicylic acid
1
1
Sesame Seed Oil
1
1
Sessile Joyweed
1
1
Silver (nanoparticles)
1
1
Syrian rue
1
1
Terminalia chebula
1
1
Vegetables: All
1
1
Verbascoside
1
1
Vitamin E: Gamma-tocotrienol
1
1
Vitex negundo
1
1
Willow Bark
1
1
Wormwood
1
1
acetyl-11-keto-beta-boswellic acid
1
1
Research Articles
1567
Cumulative Knowledge Score
2535
Overall Research Rating
EXCELLENT
View the Evidence:
2517 Abstracts with Interleukin-1 beta downregulation Research
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[+]
Pharmacological effects of berberine on models of ulcerative colitis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:937029. Epub 2022 Sep 6. PMID:
36147325
Article Published Date
: Dec 31, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Berberine
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The immunomodulatory effects of lactoferrin and its derived peptides on NF-κB signaling pathway.
Jul 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Immun Inflamm Dis. 2023 Aug ;11(8):e972. PMID:
37647433
Article Published Date
: Jul 31, 2023
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Lactoferrin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The present review provides the evidence of LLLT-dependent reduction of IL-1β, TNF-α, and MMP-13.
Aug 23, 2020
Click here to read the entire abstract
Pubmed Data
: Lasers Med Sci. 2020 Aug 24. Epub 2020 Aug 24. PMID:
32833088
Article Published Date
: Aug 23, 2020
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Osteoarthritis
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bovine lactoferrin suppresses inflammatory cytokine expression in endometrial stromal cells in chronic endometritis.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: J Reprod Immunol. 2022 Dec ;154:103761. Epub 2022 Nov 8. PMID:
36403531
Article Published Date
: Nov 30, 2022
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Endometritis
,
Inflammation
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Piperine suppresses inflammatory fibroblast-like synoviocytes derived from rheumatoid arthritis patients.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Cell Immunol. 2023 ;391-392:104752. Epub 2023 Jul 22. PMID:
37536000
Article Published Date
: Dec 31, 2022
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Piperine
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A single 20 min session of yogic breathing practice could reduce the levels of key pro-inflammatory biomarkers in saliva.
Aug 17, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2016 Aug 18 ;16:294. Epub 2016 Aug 18. PMID:
27538513
Article Published Date
: Aug 17, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Yogic Breathing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-8 downregulation
[+]
Acupuncture attenuates postoperative inflammation in patients after craniotomy.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2020 Mar ;99(11):e19071. PMID:
32176032
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Postoperative Recovery
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
An anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2013 Sep ;23(9):843-9. Epub 2012 Aug 17. PMID:
22906565
Article Published Date
: Aug 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Cyanidin 3-glucoside
,
Delphinidin
Diseases
:
Atherosclerosis
,
C-Reactive Protein
,
High Cholesterol
,
Hypercholesterolemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Dose Response
,
Natural Substance Synergy
[+]
Berberine improves negative symptoms and cognitive function in patients with chronic schizophrenia.
Apr 16, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chin Med. 2023 Apr 17 ;18(1):41. Epub 2023 Apr 17. PMID:
37069570
Article Published Date
: Apr 16, 2023
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Schizophrenia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bloodroot and echinacea offset exercise-associated effects of immune activity.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: Blood Cells Mol Dis. 2009 Nov-Dec;43(3):298-303. Epub 2009 Sep 19. PMID:
19766513
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bloodroot
,
Echinacea
Diseases
:
Immune Disorders: Low Immune Function
,
Low Immune Function: Exercise-Induced
Pharmacological Actions
:
Immunomodulatory
,
Immunostimulatory
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Breastfeeding protects against illness-induced anorexia and is mediated partially by docosahexaenoic acid.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2008 Jan;62(1):32-8. Epub 2007 Feb 21. PMID:
17311056
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Breast Milk
,
DHA (Docosahexaenoic Acid)
Diseases
:
Anorexia: Illness and Vaccine Induced
,
Vaccine-induced Toxicity
Therapeutic Actions
:
Breastfeeding
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.
Dec 06, 2006
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID:
16824715
Article Published Date
: Dec 06, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chondroprotective properties of human-enriched serum following polyphenol extract absorption.
Dec 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Dec 16 ;11(12). Epub 2019 Dec 16. PMID:
31888255
Article Published Date
: Dec 15, 2019
Study Type
: Human Study
Additional Links
Substances
:
Grape
,
Olive leaf extract
,
Polyphenols
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chondroprotective
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM.
Jun 21, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2022 Jun 22 ;22(1):165. Epub 2022 Jun 22. PMID:
35733163
Article Published Date
: Jun 21, 2022
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Inflammation
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID:
26066335
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
,
Significant Treatment Outcome
Problem Substances
:
Antidepressants
[+]
Curcumin suppresses inflammation in the mucosa of children and adults with inflammatory bowel disease.
Nov 02, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Nov 2:1-9. Epub 2009 Nov 2. PMID:
19878610
Article Published Date
: Nov 02, 2009
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID:
25948780
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bacillus coagulans
Diseases
:
C-Reactive Protein
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Microbiota
[+]
Dietary strawberries may have significant analgesic and anti-inflammatory effects in obese adults with established knee osteoarthritis.
Aug 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Aug 28 ;9(9). Epub 2017 Aug 28. PMID:
28846633
Article Published Date
: Aug 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords
:
Analgesics
,
Anti-Inflammatory Agents
,
Osteoarthritis: Knee
,
Strawberry
[+]
Effect of B vitamins supplementation on cardio-metabolic factors in patients with stable coronary artery disease.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2020 ;29(2):245-252. PMID:
32674231
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
,
Vitamin B-6
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Hypolipidemic
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
[+]
Effect of berberine on activation of TLR4-NFκB signaling pathway and NLRP3 inflammasome in patients with gout.
Sep 19, 2022
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2022 Sep 20. Epub 2022 Sep 20. PMID:
36125615
Article Published Date
: Sep 19, 2022
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Gout
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Effect of maqui-berry extract in dry eye disease - A clinical and molecular analysis.
Mar 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Indian J Ophthalmol. 2023 Apr ;71(4):1613-1618. PMID:
37026311
Article Published Date
: Mar 31, 2023
Study Type
: Human Study
Additional Links
Substances
:
Maqui
Diseases
:
Dry Eye Syndromes
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effects of 14-weeks betaine supplementation on pro-inflammatory cytokines and hematology status in professional youth soccer players.
Jun 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Soc Sports Nutr. 2021 Jun 5 ;18(1):42. Epub 2021 Jun 5. PMID:
34090451
Article Published Date
: Jun 04, 2021
Study Type
: Human Study
Additional Links
Substances
:
Betaine
Diseases
:
Athletic Performance
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effects of Sudarshan Kriya yoga and advanced meditation program on benetic expression of pro-inflammatory and antioxidants genes.
Jun 30, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2023 Jul ;15(7):e41377. Epub 2023 Jul 4. PMID:
37546047
Article Published Date
: Jun 30, 2023
Study Type
: Human Study
Additional Links
Diseases
:
Stress
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Electroacupuncture has a therapeutic effect on patients wtih osteoarthritis.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2009 Jul;29(7):529-31. PMID:
19835118
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture inhibits the corneal ROS/TXNIP/NLRP3 signaling pathway in a rat model of dry eye syndrome.
Sep 22, 2021
Click here to read the entire abstract
Pubmed Data
: Acupunct Med. 2021 Sep 23:9645284211039235. Epub 2021 Sep 23. PMID:
34553633
Article Published Date
: Sep 22, 2021
Study Type
: Human Study
Additional Links
Diseases
:
Dry Eye Syndromes
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
[+]
Etiological periodontal treatment with and without low-level laser therapy on IL-1β level.
Mar 25, 2018
Click here to read the entire abstract
Pubmed Data
: J Biol Regul Homeost Agents. 2018 Mar 26 ;32(2). Epub 2018 Mar 26. PMID:
29577710
Article Published Date
: Mar 25, 2018
Study Type
: Human Study
Additional Links
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Green tea chewing gum may be a safe adjunct for treatment of gingival inflammation.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Dent (Shiraz). 2016 Jun ;17(2):149-54. PMID:
27284561
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
Diseases
:
Gingivitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Green tea supplementation, in addition to SRP, may reduce salivary IL-1β levels in patients with chronic periodontitis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Dent. 2022 ;2022:8992313. Epub 2022 Jun 6. PMID:
35706460
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
High polyphenol intake may help individuals to reduce systemic inflammation.
May 04, 2023
Click here to read the entire abstract
Pubmed Data
: J Health Popul Nutr. 2023 May 5 ;42(1):39. Epub 2023 May 5. PMID:
37147659
Article Published Date
: May 04, 2023
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Higher flavonoid intake is associated with lower IL-1β.
Jan 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Clin Periodontol. 2020 Jan 30. Epub 2020 Jan 30. PMID:
31999847
Article Published Date
: Jan 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Periodontal Diseases
,
Periodontal Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Honey reduce the probable aggravating effects of intensive cycling training on spermatogenesis and fertility capacity in road cyclists.
Apr 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Androl. 2012 May-Jun;33(3):449-61. Epub 2011 Jun 2. PMID:
21636735
Article Published Date
: Apr 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Honey
Diseases
:
Exercise-Induced Hormone Fluctuations
,
Infertility: Male
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Immunomodulating effect of the consumption of watercress on exercise-induced inflammation.
Jul 29, 2021
Click here to read the entire abstract
Pubmed Data
: Foods. 2021 Jul 30 ;10(8). Epub 2021 Jul 30. PMID:
34441551
Article Published Date
: Jul 29, 2021
Study Type
: Human Study
Additional Links
Substances
:
Watercress
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis.
Mar 26, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Oral Health. 2023 Mar 27 ;23(1):177. Epub 2023 Mar 27. PMID:
36973728
Article Published Date
: Mar 26, 2023
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Inflammation
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-8 downregulation
[+]
Including almonds in diets as a snack may help healthy overweight and obese individuals improve nutritional status and reduce their risk for CVD.
Jul 09, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2017 Jul 10. Epub 2017 Jul 10. PMID:
28695324
Article Published Date
: Jul 09, 2017
Study Type
: Human Study
Additional Links
Substances
:
Almond
,
Vitamin E
Diseases
:
Cardiovascular Disease: Prevention
,
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2015 ;16(5):10665-73. Epub 2015 May 11. PMID:
25970751
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
Diseases
:
Gingivitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Intestinal homeostasis is a balance between pro and anti-inflammatory responses of intestinal immunocytes and could be maintained by probiotics.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Pharm Res. 2013 ;12(4):929-36. PMID:
24523774
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients.
Mar 31, 2014
Click here to read the entire abstract
Pubmed Data
: Ocul Surf. 2014 Apr ;12(2):134-45. Epub 2013 Dec 30. PMID:
24725325
Article Published Date
: Mar 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Vitamin A
,
Vitamin D
Diseases
:
Eye Diseases
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Local ice cryotherapy had beneficial effects in human non-septic knee arthritis.
Jul 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Arthritis Res Ther. 2019 Jul 30 ;21(1):180. Epub 2019 Jul 30. PMID:
31362785
Article Published Date
: Jul 29, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Arthritis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Lutein exerts anti-inflammatory effects in patients with coronary artery disease.
May 05, 2017
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2017 May 6 ;262:87-93. Epub 2017 May 6. PMID:
28527371
Article Published Date
: May 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Lutein
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Dose Response
[+]
Micronized palmitoylethanolamide, hempseed oil, and maritime pine bark dry extract for pelvic pain.
Feb 13, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cells. 2023 Feb 14 ;12(4). Epub 2023 Feb 14. PMID:
36831284
Article Published Date
: Feb 13, 2023
Study Type
: Human Study
Additional Links
Substances
:
Hemp Seed
,
Palmitoylethanolamide
,
Pine Bark Extract
Diseases
:
Chronic Pelvic Pain Syndrome
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Moderate-intensity exercise may help maintain cellular functions.
Oct 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cardiovasc Nurs. 2023 Oct 6. Epub 2023 Oct 6. PMID:
37801568
Article Published Date
: Oct 05, 2023
Study Type
: Human Study
Additional Links
Diseases
:
Aging
,
Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Telomere Protective
[+]
Montmorency cherries significantly lowered systemic inflammatory and oxidative stress induced by a series of metabolically challenging cycling bouts.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2014 ;6(2):829-43. Epub 2014 Feb 21. PMID:
24566440
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Tart Cherry
Diseases
:
C-Reactive Protein
,
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oligopin supplementation in traumatic brain injury patients in ICU reduced inflammation and improved the clinical status.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Sep ;35(9):5178-5188. Epub 2021 Aug 12. PMID:
34382717
Article Published Date
: Aug 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
Olive fruit and almond skin extract seems to protect LDL from oxidation and to prevent inflammatory status in moderately hypercholesterolemic subjects.
Aug 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32816626
Article Published Date
: Aug 17, 2020
Study Type
: Human Study
Additional Links
Substances
:
Almond
,
Olive
Diseases
:
Hypercholesterolemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Omega-3 fatty acids cause a reduction in the mRNA levels for various proteins known to be important in the pathology of osteoarthritis.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Osteoarthritis Cartilage. 2009 Jul;17(7):896-905. Epub 2009 Jan 13. PMID:
19217322
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
Eicosapentaenoic acid (EPA)
,
Omega-3 Fatty Acids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Omega-3 long chain-polyunsaturated fatty acids could have a potential therapeutic impact on chronic inflammation in Duchenne muscular dystrophy.
Sep 22, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2017 Sep 23. Epub 2017 Sep 23. PMID:
28987470
Article Published Date
: Sep 22, 2017
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Duchenne's Muscular Dystrophy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Ozone therapy is a potential therapeutic alternative for Multiple sclerosis patients.
Sep 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Sep 15 ;811:148-154. Epub 2017 Jun 13. PMID:
28623000
Article Published Date
: Sep 14, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Multiple Sclerosis
Therapeutic Actions
:
Ozone Therapy
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Phototherapy appears to be a plausible complementary option to reduce the inflammatory component in rheumatoid arthritis.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Acta Med Acad. 2015 Nov ;44(2):102-8. PMID:
26702905
Article Published Date
: Oct 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Rheumatoid Arthritis
Therapeutic Actions
:
Light Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Probiotic therapies modestly improved insulin resistance in patients with type 2 diabetes.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2018 Sep ;12(5):617-624. Epub 2018 Apr 10. PMID:
29661605
Article Published Date
: Aug 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Prune supplementation for 12 months alters the gut microbiome in postmenopausal women.
Nov 27, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Nov 28 ;13(23):12316-12329. Epub 2022 Nov 28. PMID:
36350082
Article Published Date
: Nov 27, 2022
Study Type
: Human Study
Additional Links
Substances
:
Prune
Diseases
:
Postmenopausal Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
[+]
Psilocybin induces acute and persisting alterations in immune status in healthy volunteers.
Oct 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Behav Immun. 2023 Nov ;114:299-310. Epub 2023 Sep 7. PMID:
37689275
Article Published Date
: Oct 31, 2023
Study Type
: Human Study
Additional Links
Substances
:
Psilocybin
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Punica granatum peel extract as adjunct irrigation to nonsurgical treatment of chronic gingivitis.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Complement Ther Clin Pract. 2021 May ;43:101383. Epub 2021 Apr 2. PMID:
33862350
Article Published Date
: Apr 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Gingivitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Extracts
[+]
Punicalagin might be one of natural therapeutic compounds for relieving rheumatoid arthritis progression.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm Res. 2021 ;14:1901-1913. Epub 2021 May 12. PMID:
34012288
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Regulation of NLRP3 inflammasome by zinc supplementation in Behçet's disease patients.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2022 Aug ;109:108825. Epub 2022 May 10. PMID:
35561480
Article Published Date
: Jul 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Zinc
Diseases
:
Behcet Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Role of ascorbic acid infusion in critically ill patients with transfusion-related acute lung injury.
Dec 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Clin Pharmacol. 2021 Dec 5. Epub 2021 Dec 5. PMID:
34866234
Article Published Date
: Dec 04, 2021
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-8 downregulation
,
Malondialdehyde Down-regulation
[+]
Sesamin can relieve clinical symptoms and pathological changes that caused by inflammatory impairment in patients with rheumatoid arthritis.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Sep ;33(9):2421-2428. Epub 2019 Jul 15. PMID:
31309643
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Sesamin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia.
Apr 18, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Apr 19 ;24(8). Epub 2019 Apr 19. PMID:
31010153
Article Published Date
: Apr 18, 2019
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Pre-Eclampsia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sinomenine inhibits the progression of rheumatoid arthritis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2018 ;9:2228. Epub 2018 Sep 26. PMID:
30319663
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Sinomenine
Diseases
:
Arthritis
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Successful therapy of Clostridium difficile infection with fecal microbiota transplantation.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Physiol Pharmacol. 2016 Dec ;67(6):859-866. PMID:
28195066
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Clostridium Infections
,
Diarrhea
,
Inflammation
Therapeutic Actions
:
Microbiota Transfer Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Supplementation with algal sulfated polysaccharide improved plasma lipids, anti-inflammatory activity, and microbiome shifts in overweight participants.
Aug 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2022 Aug 2 ;20(8). Epub 2022 Aug 2. PMID:
36005503
Article Published Date
: Aug 01, 2022
Study Type
: Human Study
Additional Links
Substances
:
Seaweed
Diseases
:
C-Reactive Protein
,
Inflammation
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
The 3-year effect of the mediterranean diet intervention on inflammatory biomarkers related to cardiovascular disease.
Jul 21, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomedicines. 2021 Jul 22 ;9(8). Epub 2021 Jul 22. PMID:
34440065
Article Published Date
: Jul 21, 2021
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Diseases
,
Inflammation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Risk Reduction
[+]
The effects of saffron in conjunction with concurrent training on body composition, glycaemic status, and inflammatory markers.
Jan 08, 2022
Click here to read the entire abstract
Pubmed Data
: Br J Clin Pharmacol. 2022 Jan 9. Epub 2022 Jan 9. PMID:
35001410
Article Published Date
: Jan 08, 2022
Study Type
: Human Study
Additional Links
Substances
:
Saffron
Diseases
:
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The findings of the present trial suggested that curcumin may exert immunomodulatory effects via altering the circulating concentrations of IL-1β, IL-4, and VEGF.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: ScientificWorldJournal. 2014 ;2014:898361. Epub 2014 Feb 11. PMID:
24678280
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
VEGFR3 inhibition
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
The impact of virgin coconut oil and high-oleic safflower oil on body composition, lipids, and inflammatory markers in postmenopausal women.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28277823
Article Published Date
: Mar 08, 2017
Study Type
: Human Study
Additional Links
Substances
:
Safflower
,
Virgin Coconut Oil
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Oils
[+]
The impacts of synbiotic supplementation on periodontal indices and biomarkers of oxidative stress in type 2 diabetes mellitus patients with chronic periodontitis.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetes Metab Syndr Obes. 2020 ;13:19-29. Epub 2020 Jan 6. PMID:
32021348
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
FOS (Fructooligosaccharides)
,
Probiotics
Diseases
:
Diabetes Mellitus: Type 2
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Malonaldehyde (MDA) Down-Regulation
[+]
The oral intake of Pycnogenol down-regulated the gene expression of various cartilage degradation markers in the patients' chondrocytes.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Dec 16 ;17(1):537. Epub 2017 Dec 16. PMID:
29246219
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
The present study provides evidence that Diabetea tea has hypoglycemic and antihyperlipidemic properties.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:1069-1077. Epub 2016 Oct 27. PMID:
27989874
Article Published Date
: Dec 23, 2016
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
Diseases
:
Diabetes Mellitus: Type 2
,
Inflammation
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-8 downregulation
Additional Keywords
:
BLACK TEA
,
Diabetes mellitus: Type 2
,
Hypoglycemic Agents
,
Hypolipidemic
,
Inflammation
,
Plant Extracts
[+]
The role of yoga in inflammatory markers.
Feb 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Behav Immun Health. 2022 Mar ;20:100421. Epub 2022 Feb 1. PMID:
35199049
Article Published Date
: Feb 28, 2022
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Treatment with melittin induces apoptosis and autophagy of fibroblastlike synoviocytes in patients with rheumatoid arthritis.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2020 ;21(8):734-740. PMID:
31820689
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Autophagy Inhibitors
,
Interleukin-1 beta downregulation
[+]
Vitamin D modulates systemic inflammation in patients with severe COVID-19.
Aug 23, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Life Sci. 2022 Aug 24 ;307:120909. Epub 2022 Aug 24. PMID:
36028169
Article Published Date
: Aug 23, 2022
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Coronavirus Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Walking and taking vitamin C can reduce levels of ROS, 8-OHdG and IL-1β, but not TNF-α, in overweight/obese participants.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Public Health. 2022 ;10:1024864. Epub 2022 Oct 5. PMID:
36276369
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Inflammation
,
Obesity
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
[+]
Weight loss and vitamin D supplementation may act synergistically to reduce levels of meta-inflammation.
Sep 23, 2018
Click here to read the entire abstract
Pubmed Data
: Clin Endocrinol (Oxf). 2018 Sep 24. Epub 2018 Sep 24. PMID:
30246883
Article Published Date
: Sep 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Inflammation
,
Obesity
Therapeutic Actions
:
Weight Reduction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Anthocyanins from wild blueberry reduce the activation of NF-kB and mitigate IL-1B activity human intestinal cells.
Aug 20, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2014 Aug 20 ;62(33):8346-51. Epub 2014 Aug 8. PMID:
25075866
Article Published Date
: Aug 20, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Anthocyanins
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory effect of mushrooms in dengue-infected human monocytes.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Trop Biomed. 2019 Dec 1 ;36(4):1087-1098. PMID:
33597478
Article Published Date
: Nov 30, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Medicinal Mushrooms
Diseases
:
Dengue
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-tumor and immunoregulatory effects of fermented papaya preparation.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2016 ;17(7):3077-84. PMID:
27509932
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Papaya: Fermented
Diseases
:
Cancers: All
Pharmacological Actions
:
Antineoplastic Agents
,
Chemotherapeutic
,
Immunomodulatory
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside potentially serve as a promising and effective therapeutic agent for treating osteoarthritis patients.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2019 Aug ;41(4):497-503. Epub 2019 Jul 11. PMID:
31293216
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Astragaloside
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Nitric Oxide Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Betulinic acid inhibited IL-1β-induced inflammation in osteoarthritis chondrocytes by activating PPAR-γ.
Sep 17, 2015
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Sep 18. Epub 2015 Sep 18. PMID:
26391061
Article Published Date
: Sep 17, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Betulinic acid
Diseases
:
Inflammation
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Diosmetin exhibits anti-proliferative and anti-inflammatory effects on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.
Dec 12, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Dec 13. Epub 2019 Dec 13. PMID:
31833613
Article Published Date
: Dec 12, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Diosmetin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Ficus carica attenuates denervated skeletal muscle atrophy.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2020 ;11:580223. Epub 2020 Dec 3. PMID:
33343385
Article Published Date
: Dec 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Fig
Diseases
:
Muscle Atrophy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Honeys with anti-inflammatory capacity can alter the elderly gut microbiota in an ex vivo gut model.
Oct 29, 2022
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2022 Oct 30 ;392:133229. Epub 2022 May 18. PMID:
35679723
Article Published Date
: Oct 29, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Honey
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID:
22348531
Article Published Date
: Aug 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Metabolomics profiling reveals berberine-inhibited inflammatory response in human gingival fibroblasts.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:940224. Epub 2022 Aug 22. PMID:
36071855
Article Published Date
: Dec 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Paeoniflorin may provide a new therapeutic approach to regulate P2X7R-mediated pathologic responses of primary Sjögren's syndrome.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Sep ;28(1):115-20. Epub 2015 Jun 3. PMID:
26049028
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Sjogren's Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Jun ;6(6):1960-7. PMID:
25996641
Article Published Date
: May 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Phloretin
Diseases
:
Experimental Lung Inflammation
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Prostaglandin PGE2 downregulation
[+]
Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.
Mar 21, 2018
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2018 Mar 22 ;31(3):134-143. Epub 2018 Mar 22. PMID:
29566388
Article Published Date
: Mar 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Punicalagin
Diseases
:
Air Pollution Linked Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol may be a useful preventative therapeutic for pregnancies complicated by inflammation and insulin resistance.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0173373. Epub 2017 Mar 9. PMID:
28278187
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Gestational Diabetes
,
Inflammation
,
Pregnancy Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Rosmarinic acid may be a potential candidate for the treatment of psoriasis.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jun 15 ;155:189-94. Epub 2016 May 17. PMID:
27210890
Article Published Date
: Jun 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect.
Mar 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2018 Mar 12 ;15(1):75. Epub 2018 Mar 12. PMID:
29530050
Article Published Date
: Mar 11, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The antioxidants astaxanthin and vitamin C promoted a significant improvement in the function of neutrophils and in the redox status.
Jun 28, 2012
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2012 Jun 29. Epub 2012 Jun 29. PMID:
22750055
Article Published Date
: Jun 28, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Astaxanthin
,
Vitamin C
Diseases
:
Advanced Glycation Endproduct (AGE) Formation
,
Neutrophils: Damaged
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D attenuates human gingival fibroblast inflammatory cytokine production following advanced glycation end product interaction with receptors for AGE.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Periodontal Res. 2019 Apr ;54(2):154-163. Epub 2018 Oct 8. PMID:
30295316
Article Published Date
: Mar 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin D
Diseases
:
Advanced Glycation End products (AGE)
,
Endotoxemia
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Vitexin alleviates interleukin-1β induced inflammatory responses in chondrocytes from osteoarthritis patients.
May 03, 2019
Click here to read the entire abstract
Pubmed Data
: Scand J Immunol. 2019 May 4:e12773. Epub 2019 May 4. PMID:
31055848
Article Published Date
: May 03, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitexins
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ameliorative effect of traditional polyherbal formulation on TNF-α, IL-1β and Caspase-3 expression in kidneys.
Jul 10, 2023
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2023 Jul 11 ;318(Pt A):116900. Epub 2023 Jul 11. PMID:
37442489
Article Published Date
: Jul 10, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
,
Ellagic Acid
,
Ferulic acid
,
Quercetin
Diseases
:
Chronic Kidney Disease (CKD)
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Sodium Fluoride
[+]
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2023 Jul 1 ;324:121743. Epub 2023 Apr 27. PMID:
37120013
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
[+]
Anti-tumor activity of arjunolic acid against ehrlich ascites carcinoma cells.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Aug ;82:28-34. Epub 2016 May 3. PMID:
27470335
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Terminalia
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antineoplastic Agents
,
Apoptotic
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer's disease.
Jan 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Feb ;9(2):e13411. Epub 2023 Feb 3. PMID:
36820018
Article Published Date
: Jan 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin ameliorates radiation-induced lung injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2022 ;2022:2765354. Epub 2022 Jun 24. PMID:
35783527
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bromelain extract exerts antiarthritic effects via chondroprotection.
Oct 22, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Plants (Basel). 2021 Oct 23 ;10(11). Epub 2021 Oct 23. PMID:
34834636
Article Published Date
: Oct 22, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bromelain
Diseases
:
Inflammation
,
Osteoarthritis
,
Rheumatoid Arthritis
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Chondroprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Celastrol inhibits TXNIP expression to protect pancreatic β cells in diabetic mice.
Jul 04, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Jul 5 ;104:154316. Epub 2022 Jul 5. PMID:
35820305
Article Published Date
: Jul 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Celastrol
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Pancreato Protective Agents
[+]
Chlorogenic acid may be a viable therapeutic option for bacterial and viral-induced acute respiratory distress syndrome-like pathology.
May 30, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Sci (Lond). 2023 May 31 ;137(10):785-805. PMID:
36951146
Article Published Date
: May 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Acute Respiratory Distress Syndrome
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diallyl trisulfide inhibits monosodium urate-induced NLRP3 inflammasome activation.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Apr ;112:154705. Epub 2023 Feb 9. PMID:
36796188
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI/HSP70/NF-κB anti-inflammatory axis.
Feb 14, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Feb 15 ;99:153991. Epub 2022 Feb 15. PMID:
35217435
Article Published Date
: Feb 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.
Jan 11, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2022 Jan 12 ;23(2). Epub 2022 Jan 12. PMID:
35054997
Article Published Date
: Jan 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Farrerol alleviates myocardial ischemia/reperfusion injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:879232. Epub 2022 Apr 13. PMID:
35496295
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Farrerol ameliorates TNBS-induced colonic inflammation.
Jul 12, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 13 ;19(7). Epub 2018 Jul 13. PMID:
30011811
Article Published Date
: Jul 12, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Formononetin improves the inflammatory response and bone destruction in knee joint lesions.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 Apr 1. Epub 2023 Apr 1. PMID:
37002905
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Formononetin
Diseases
:
Bone Diseases
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Osteoprotective
[+]
Fucoxanthin exert dose-dependent antifibrotic and anti-inflammatory effects on CCl4-induced liver fibrosis.
Aug 31, 2023
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2023 Sep ;77(4):953-963. Epub 2023 Jun 30. PMID:
37391684
Article Published Date
: Aug 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Liver Cirrhosis
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation.
Aug 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID:
30121057
Article Published Date
: Aug 15, 2018
Study Type
: Human: Case Report
Additional Links
Substances
:
Ginger
Diseases
:
Bronchopulmonary Dysplasia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginkgolide B functions as a determinant constituent of Ginkgolides in alleviating lipopolysaccharide-induced lung injury.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Jul ;81:71-78. Epub 2016 Apr 11. PMID:
27261579
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury.
Mar 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2021 Apr ;47(4). Epub 2021 Mar 2. PMID:
33649807
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome.
Feb 28, 2023
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2023 Mar 1 ;303:115948. Epub 2022 Nov 21. PMID:
36423713
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Glycyrrhizin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Grape seed extract attenuates demyelination in experimental autoimmune encephalomyelitis.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2023 May ;29(5):394-404. Epub 2023 Jan 6. PMID:
36607588
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Healing effect of carboxymethyl chitosan-plantamajoside hydrogel on burn wound skin.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Burns. 2022 Jun ;48(4):902-914. Epub 2022 Jan 29. PMID:
35153110
Article Published Date
: May 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Plantago
Diseases
:
Burns
,
Wound Healing
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Honokiol alleviates ulcerative colitis by targeting PPAR-γ-TLR4-NF-κB signaling.
Jul 25, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2022 Jul 26 ;111:109058. Epub 2022 Jul 26. PMID:
35901530
Article Published Date
: Jul 25, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Honokiol
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lactobacillus modulates chlamydia infectivity and genital tract pathology in vitro and in vivo.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Microbiol. 2022 ;13:877223. Epub 2022 Apr 28. PMID:
35572713
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lactobacillus probiotics
Diseases
:
Chlamydia Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lutein attenuates Propionibacterium acnes-induced inflammation.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2023 Apr ;117:109937. Epub 2023 Mar 8. PMID:
37012890
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lutein
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Macrophage-targeted berberine-loaded β-glucan nanoparticles enhance the treatment of ulcerative colitis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2022 ;17:5303-5314. Epub 2022 Nov 14. PMID:
36406639
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
,
Beta-glucan
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Narirutin exerts anti-inflammatory activity by inhibiting NLRP3 inflammasome activation.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 Apr ;37(4):1293-1308. Epub 2023 Feb 7. PMID:
36751854
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Oral administration of cryptotanshinone-encapsulated nanoparticles for the amelioration of ulcerative colitis.
Jan 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Mol Bioeng. 2022 Feb ;15(1):129-136. Epub 2021 Oct 26. PMID:
35096188
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Oral administration of Ulmus davidiana extract suppresses interleukin-1β expression in LPS-induced immune responses and lung injury.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Genes Genomics. 2020 01 ;42(1):87-95. Epub 2019 Nov 17. PMID:
31736005
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Elm tree
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Med Sci. 2022 ;19(4):681-694. Epub 2022 Mar 28. PMID:
35582418
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Piperine attenuates cigarette smoke-induced oxidative stress, lung inflammation, and epithelial-mesenchymal transition.
Nov 24, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Nov 25 ;23(23). Epub 2022 Nov 25. PMID:
36499047
Article Published Date
: Nov 24, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Piperine
Diseases
:
Lung Inflammation
,
Oxidative Stress
,
Smoking
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pterostilbene interferes with lipopolysaccharide-induced myocardial injury,
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2022 ;13:862187. Epub 2022 Mar 24. PMID:
35399278
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Rosmarinic acid exerts anti-inflammatory effect and relieves oxidative stress via Nrf2 activation in carbon tetrachloride-induced liver damage.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2022 ;66. Epub 2022 Nov 18. PMID:
36590857
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Tanshinone IIA mediates protection from diabetes kidney disease.
Nov 14, 2023
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2023 Nov 15 ;316:116667. Epub 2023 May 29. PMID:
37257702
Article Published Date
: Nov 14, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Diabetic Nephropathy
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Renoprotective
[+]
Tanshinone IIA protected against lipopolysaccharide-induced brain injury.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Aug 1 ;13(15):8304-8312. Epub 2022 Aug 1. PMID:
35839080
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The aqueous extracts of Ageratum conyzoides inhibit inflammation by suppressing NLRP3 inflammasome activation.
Jun 11, 2023
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2023 Jun 12 ;309:116353. Epub 2023 Mar 10. PMID:
36907476
Article Published Date
: Jun 11, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Billygoat Weed
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The neuroprotection of verbascoside in Alzheimer's disease mediated through mitigation of neuroinflammation.
Mar 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Mar 29 ;14(7). Epub 2022 Mar 29. PMID:
35406030
Article Published Date
: Mar 28, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Transforming growth factor beta (TGF-β) upregulation
[+]
The protective effect of mangiferin on osteoarthritis.
Jan 24, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Physiol Res. 2022 03 25 ;71(1):135-145. Epub 2022 Jan 19. PMID:
35043648
Article Published Date
: Jan 24, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
NF-kappaB Inhibitor
[+]
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines.
Aug 17, 2020
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32812061
Article Published Date
: Aug 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2020 Aug ;42(4):306-313. Epub 2020 May 18. PMID:
32419528
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effect of a flavonoid-rich extract of orange juice in adult zebrafish subjected to Vibrio anguillarum-induced enteritis.
Apr 26, 2020
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2020 Apr 27:1-4. Epub 2020 Apr 27. PMID:
32338069
Article Published Date
: Apr 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Orange
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin protects LPS-induced blood-brain barrier damage and activates Nrf2-mediated antioxidant stress pathway
Jun 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Jul ;96:107725. Epub 2021 May 28. PMID:
34162131
Article Published Date
: Jun 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cardioprotective effect of thymol against adrenaline-induced myocardial injury in rats.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2020 Jul ;6(7):e04431. Epub 2020 Jul 21. PMID:
32715125
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Thymol
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
[+]
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Jul 15, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Anim. 2020 Jul 16. Epub 2020 Jul 16. PMID:
32669479
Article Published Date
: Jul 15, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Parkinson's Disease
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ficus carica polysaccharide attenuates DSS-induced ulcerative colitis in C57BL/6 mice.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Jul 1 ;11(7):6666-6679. Epub 2020 Jul 13. PMID:
32658237
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adipocyte. 2020 Dec ;9(1):302-312. PMID:
32580621
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Aug 25:960327120949618. Epub 2020 Aug 25. PMID:
32840384
Article Published Date
: Aug 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lactoferrin Decreases Inflammatory Response by Cystic Fibrosis Bronchial Cells Invaded with Burkholderia Cenocepacia Iron-Modulated Biofilm
Sep 30, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1057-68. PMID:
22230411
Article Published Date
: Sep 30, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Cystic Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.
Jul 24, 2020
Click here to read the entire abstract
Pubmed Data
: IUBMB Life. 2020 Jul 25. Epub 2020 Jul 25. PMID:
32710811
Article Published Date
: Jul 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Jul 15 ;253:117671. Epub 2020 Apr 24. PMID:
32335165
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Piperine
Diseases
:
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
1,8-cineol appears to be able to augment protection against influenza viral infection in mice.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Aug ;39(4):1582-93. PMID:
27351430
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Eucalyptus
Diseases
:
Inflammation
,
Influenza
,
Pneumonia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression.
Aug 08, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Aug 9. Epub 2021 Aug 9. PMID:
34369548
Article Published Date
: Aug 08, 2021
Study Type
: Animal Study
Additional Links
Substances
:
18β-Glycyrrhetinic Acid
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Nrf2 activation
[+]
18β-Glycyrrhetinic acid significantly attenuated H. pylori-infected gastritis in gerbils.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2016 ;2016:4943793. Epub 2016 Feb 24. PMID:
27006947
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
18β-Glycyrrhetinic Acid
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2017 08 ;28(5):365-374. PMID:
28410266
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-Gingerol abates benzo[a]pyrene-induced colonic injury.
Apr 17, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2019 Apr 18 ;307:1-7. Epub 2019 Apr 18. PMID:
31004597
Article Published Date
: Apr 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Benzo[a]pyrene-induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Benzo(a)pyrene
[+]
6-gingerol ameliorates metabolic disorders by inhibiting hypertrophy and hyperplasia.
Jan 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Feb ;146:112491. Epub 2021 Dec 9. PMID:
34896967
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
[+]
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Jul 15:173294. Epub 2020 Jul 15. PMID:
32681941
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer.
Jun 04, 2020
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2020 Jun 5 ;142:111483. Epub 2020 Jun 5. PMID:
32512025
Article Published Date
: Jun 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Problem Substances
:
Benzo(a)pyrene
[+]
6-Gingerol exerts protective effects against ischemia reperfusion induced intestinal mucosa injury.
Feb 03, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Feb 4 ;119:137-148. Epub 2017 Feb 4. PMID:
28167239
Article Published Date
: Feb 03, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ischemia
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Shogaol inhibits osteoclastogenesis and alveolar bone resorption in ligature-induced periodontitis.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2019 Nov 1. Epub 2019 Nov 1. PMID:
31675438
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Shogaol reduces progression of experimental endometriosis.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2018 Nov ;22(6):627-636. Epub 2018 Oct 25. PMID:
30402023
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
[+]
6-Shogaol treatment produced beneficial effects for TBI-induced anxiety/depression-like behaviors.
Jan 10, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ACS Omega. 2022 Jan 11 ;7(1):140-148. Epub 2021 Dec 28. PMID:
35036685
Article Published Date
: Jan 10, 2022
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Brain Injury: Traumatic
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A combination of apple vinegar drink with Bacillus coagulans ameliorates high fat diet-induced body weight gain, insulin resistance and hepatic steatosis.
Aug 18, 2020
Click here to read the entire abstract
Pubmed Data
: Nutrients. 2020 Aug 19 ;12(9). Epub 2020 Aug 19. PMID:
32825073
Article Published Date
: Aug 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple Cider Vinegar
Diseases
:
High Fat Diet
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
A combination therapy of betulinic acid and fluvastatin that reduces the risk of both rheumatoid arthritis and CVD.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Sep ;93:681-694. Epub 2017 Jul 8. PMID:
28692940
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Arthritis
,
Cardiovascular Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A compound in Chinese skullcap known as baicalein reduces the inflammatory process in a rodent model of diabetic retinopathy
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Invest Ophthalmol Vis Sci. 2009 May;50(5):2319-27. Epub 2008 Nov 14. PMID:
19011009
Article Published Date
: May 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chinese Skullcap
Diseases
:
Brain: Microglial Activation
,
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
A dietary supplement of nuciferine rich in lotus leaf may have potential for the prevention and treatment of hyperuricemia with kidney inflammation.
Jan 14, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jan 15 ;747:59-70. Epub 2014 Dec 8. PMID:
25499818
Article Published Date
: Jan 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lotus
Diseases
:
Hyperuricemia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID:
30919084
Article Published Date
: Mar 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.
May 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 May 11 ;25(9). Epub 2020 May 11. PMID:
32403241
Article Published Date
: May 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Pomegranate
,
Propolis: Bee
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
[+]
A natural compound mixture ameliorates psoriasis-like skin lesions.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2020 ;2020:9416962. Epub 2020 Oct 22. PMID:
33149756
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
,
Emodin
,
Genipin
,
Ginsenosides
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2021 ;65. Epub 2021 Jul 1. PMID:
34262422
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Autophagy Up-regulation
,
Gastrointestinal Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A pine nut polysaccharide is a promising functional food to prevent alcohol induced-liver injury.
Nov 08, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Nov 9. Epub 2019 Nov 9. PMID:
31712149
Article Published Date
: Nov 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pine Nut
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
A proprietary blend of herbs suppresses bladder oxidative stress and inflammation in a rat model of partial bladder outlet obstruction.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Urol. 2009 Jul;182(1):382-90. Epub 2009 May 17. PMID:
19447421
Article Published Date
: Jul 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Aspen
,
Horsetail
,
Pipsisssewa
,
Pulsatilla pratensis
,
Wheat Bran
Diseases
:
Bladder Dysfunction
,
Bladder Outlet Obstruction
,
Oxidative Stress
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A standardised Andrographis paniculata Burm. Nees aqueous extract prevents Lipopolysaccharide-induced cognitive deficits.
Feb 28, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: J Adv Res. 2019 Mar ;16:87-97. Epub 2018 Nov 30. PMID:
30899592
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A standardized extract of neem has neuroprotective effects in partial sciatic nerve injury.
Dec 31, 2016
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Article Publish Status
: This is a free article.
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Pubmed Data
: EXCLI J. 2017 ;16:546-565. Epub 2017 Apr 18. PMID:
28694757
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Neem
Diseases
:
Nerve Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A variety of orange by-products could be used as food supplements in the potential amelioration of inflammatory bowel diseases.
Sep 18, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Sep 19 ;9(9):4888-4896. PMID:
30167607
Article Published Date
: Sep 18, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Orange
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A. princeps extract might be developed as therapeutic potential in the treatment of inflammasome-mediated inflammatory disorders, such as gouty arthritis.
Dec 31, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Mediators Inflamm. 2018 ;2018:6054069. Epub 2018 Mar 4. PMID:
29686531
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Japanese mugwort
Diseases
:
Arthritis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Aastragaloside IV can alleviate inflammation and enhance immunity in rats with experimental periodontitis.
Apr 24, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Braz Oral Res. 2019 Apr 25 ;33:e032. Epub 2019 Apr 25. PMID:
31038567
Article Published Date
: Apr 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunostimulatory
,
Interleukin-1 beta downregulation
,
Interleukin-2 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin alleviates neuroinflammation and oxidative stress injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Neurosci. 2022 Jan 1 ;13(1):483-494. Epub 2022 Dec 21. PMID:
36590896
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin attenuates mice endotoxin-induced acute lung injury via augmentation of heme oxygenase-1 activity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2018 Apr ;26(2):635-643. Epub 2017 Oct 7. PMID:
28988328
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endotoxemia
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin suppresses IL-1 β-induced expression of matrix metalloproteinases in chondrocytes and protects against osteoarthritis.
Dec 31, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Biomed Res Int. 2020 ;2020:2328401. Epub 2020 Oct 26. PMID:
33195691
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
NF-kappaB Inhibitor
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acetyl-11-keto-beta-boswellic acid promotes sciatic nerve repair after injury.
Nov 30, 2022
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Article Publish Status
: This is a free article.
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Pubmed Data
: Neural Regen Res. 2022 Dec ;17(12):2778-2784. PMID:
35662229
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
Diseases
:
Sciatic Nerve Crush Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Nerve Regeneration
[+]
Achillea Millefolium hydro alcoholic extract protects pancreatic cells.
Dec 31, 2013
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Article Publish Status
: This is a free article.
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Pubmed Data
: Int J Mol Cell Med. 2014 ;3(4):255-62. PMID:
25635252
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Yarrow
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Pancreato Protective Agents
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
[+]
Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Mar 1 ;213:159-165. Epub 2017 Nov 21. PMID:
29174375
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kiwifruit
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Extracts
[+]
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID:
29128856
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Activity of isoflavone biochanin A in chronic experimental toxoplasmosis: impact on inflammation.
Jun 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Parasitol Res. 2022 Jun 17. Epub 2022 Jun 17. PMID:
35710847
Article Published Date
: Jun 16, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Toxoplasmosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Administering crocin ameliorates anxiety-like behaviors and reduces the inflammatory response in amyloid-beta induced neurotoxicity.
Mar 07, 2021
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2021 Mar 8. Epub 2021 Mar 8. PMID:
33686675
Article Published Date
: Mar 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Anxiety
,
Brain Inflammation
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Administration of biochanin A can improve and postpone retinopathy.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Can J Diabetes. 2018 Dec ;42(6):639-644. Epub 2018 Apr 3. PMID:
30054234
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Administration of Epigallocatechin-3-gallate resulted in a significant reduction in bone loss.
Sep 06, 2015
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Sep 7. Epub 2015 Sep 7. PMID:
26359545
Article Published Date
: Sep 06, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Gingivitis
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Adrenal sympathetic nerve mediated the anti-inflammatory effect of electroacupuncture at ST25 acupoint in a model of sepsis.
Oct 26, 2022
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anat Rec (Hoboken). 2022 Oct 27. Epub 2022 Oct 27. PMID:
36300612
Article Published Date
: Oct 26, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Sepsis
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Aegle marmelos bark extract is active in attenuating the neuropathic pain caused by vincristine.
Jun 20, 2019
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2019 Jun 21:1-11. Epub 2019 Jun 21. PMID:
31221045
Article Published Date
: Jun 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Aerobic exercise improves depressive-like behavior.
Aug 08, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Life (Basel). 2023 Aug 9 ;13(8). Epub 2023 Aug 9. PMID:
37629568
Article Published Date
: Aug 08, 2023
Study Type
: Animal Study
Additional Links
Diseases
:
Depression
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
[+]
Agaricus blazei polysaccharide has a protective effect on cadmium induced damage in chicken spleens.
Oct 13, 2017
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2017 Oct 14. Epub 2017 Oct 14. PMID:
29032405
Article Published Date
: Oct 13, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Agaricus Blazei
Diseases
:
Cadmium Poisoning
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alantolactone suppresses proliferation and the inflammatory response in human HaCaT keratinocytes.
Jun 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Life (Basel). 2021 Jun 25 ;11(7). Epub 2021 Jun 25. PMID:
34202301
Article Published Date
: Jun 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Elecampane
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-23 Downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Albiflorin alleviates ovalbumin (OVA)-induced pulmonary inflammation in asthmatic mice.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2019 ;11(12):7300-7309. Epub 2019 Dec 15. PMID:
31934279
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Peony
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Albiflorin attenuates high glucose-induced endothelial apoptosis via suppressing PARP1/NF-κB signaling pathway.
Nov 09, 2022
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2022 Nov 10. Epub 2022 Nov 10. PMID:
36357814
Article Published Date
: Nov 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Peony
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alkali-soluble sweet potato polysaccharide can be developed as a novel anti-inflammation agent.
Mar 19, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Mar 20 ;131:484-494. Epub 2019 Mar 20. PMID:
30904524
Article Published Date
: Mar 19, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sweet Potato: Purple
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Alleviation effects of grape seed proanthocyanidin extract on inflammation and oxidative stress in a D-galactose-induced aging mouse model.
Feb 06, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Feb 7 ;13(3):1348-1359. Epub 2022 Feb 7. PMID:
35043135
Article Published Date
: Feb 06, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gut-brain Axis
,
Gut-Lung-Axis
,
Proanthocyanidins
[+]
Alleviative effects of pinostrobin against cadmium-induced renal toxicity.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Front Nutr. 2023 ;10:1175008. Epub 2023 May 24. PMID:
37342552
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cadmium
[+]
Allicin attenuates liver oxidative stress and inflammation.
Sep 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2016 Sep 28 ;64(38):7104-13. Epub 2016 Sep 19. PMID:
27584700
Article Published Date
: Sep 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alcohol Toxicity
,
Fatty Liver
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Alcohol Toxicity
,
Allicin
,
Anti-Inflammatory Agents
,
Fatty Liver
,
Inflammation
,
oxidative stress
[+]
Allicin modifies the composition and function of the gut microbiota in alcoholic hepatic steatosis mice.
Mar 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2020 Mar 11 ;68(10):3088-3098. Epub 2020 Feb 27. PMID:
32050766
Article Published Date
: Mar 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
