Interleukin-10 upregulation

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18 Substances Researched for Interleukin-10 upregulation
NameACCKFocus
Vitamin D321Locked
Camel Milk 110Locked
Chocolate110Locked
Probiotics110Locked
Shiitake Mushroom 110Locked
Soup110Locked
Apigenin12Locked
Banana12Locked
Chinese Skullcap 12Locked
Loquat Seeds12Locked
Phytosterols12Locked
Sesame Seed Oil 12Locked
Chili pepper11Locked
Curcumin11Locked
Moringa oleifera11Locked
Red Clover11Locked
Rice Bran11Locked
Saccharomyces Boulardii11Locked

View the Evidence:
337 Abstracts with Interleukin-10 upregulation Research

[+]

Pharmacological effects of berberine on models of ulcerative colitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:937029. Epub 2022 Sep 6. PMID: 36147325
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Berberine
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects of oral supplementation with curcumin.Aug 08, 2021

Pubmed Data : Nutr Rev. 2021 Aug 9 ;79(9):1043-1066. PMID: 34378053
Article Published Date : Aug 08, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Curcumin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This meta-analysis suggests that resveratrol can be a clinically effective therapy for rheumatoid arthritis.Nov 04, 2021

Pubmed Data : Eur J Pharmacol. 2021 Nov 5 ;910:174504. Epub 2021 Sep 11. PMID: 34520733
Article Published Date : Nov 04, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Resveratrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

1, 25-dihydroxyvitamin D3 downregulates cytotoxic effector response in pulmonary tuberculosis.Aug 31, 2018

Pubmed Data : Int Immunopharmacol. 2018 Sep ;62:251-260. Epub 2018 Jul 20. PMID: 30032050
Article Published Date : Aug 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Tuberculosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation
[+]

Alpha-lipoic acid modifies circulating angiogenic factors in patients with type 2 diabetes mellitus.Jan 31, 2015

Pubmed Data : Diabetes Res Clin Pract. 2015 Feb ;107(2):273-9. Epub 2014 Dec 3. PMID: 25511715
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Interleukin-10 upregulation, Vascular Endothelial Growth Factor Regulator
[+]

Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.Oct 11, 2020

Pubmed Data : Dig Liver Dis. 2020 Oct 12. Epub 2020 Oct 12. PMID: 33060043
Article Published Date : Oct 11, 2020
Study Type : Human Study
Additional Links
Substances : Hydroxytyrosol, Vitamin E
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Beneficial effects of Phyllanthus amarus leaves on hangover symptoms.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2019 Dec ;57(1):145-153. PMID: 30922154
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Substances : Phyllanthus amarus
Diseases : Alcohol Toxicity , Hangover
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-8 upregulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Beta-glucan modulates waist circumference and inflammation in obese subjects.Mar 04, 2017

Pubmed Data : J Diet Suppl. 2017 Mar 4 ;14(2):173-185. Epub 2016 Aug 11. PMID: 27715351
Article Published Date : Mar 04, 2017
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Inflammation, Obesity
Pharmacological Actions : Hypotensive, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Camel milk had a regulatory effect on multiple parameters of inflammatory mediators, immunomodulators, antiapoptosis, and antioxidants.Oct 31, 2015

Pubmed Data : Nutr Cancer. 2015 Nov-Dec;67(8):1305-13. Epub 2015 Oct 22. PMID: 26492130
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Substances : Camel Milk
Diseases : Hepatitis C
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory, Interleukin-10 upregulation
Additional Keywords : Vitamin D3
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Chaihu Shihuang soup can significantly regulate cytokine and improve early recovery of severe acute pancratitis.May 31, 2009

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 Jun ;34(12):1582-4. PMID: 19777852
Article Published Date : May 31, 2009
Study Type : Human Study
Additional Links
Substances : Soup
Diseases : Pancreatitis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Significant Treatment Outcome
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Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

Pubmed Data : Eur J Appl Physiol. 2020 Jul ;120(7):1531-1540. Epub 2020 May 2. PMID: 32361773
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Substances : Curcumin, Turmeric
Diseases : Inflammation, Muscle Damage: Exercise-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Additional Keywords : Plant Extracts
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Curcumin could be used for improving nasal airflow and modulating immune response in patients with allergic rhinitis.Nov 30, 2016

Pubmed Data : Ann Allergy Asthma Immunol. 2016 Dec ;117(6):697-702.e1. Epub 2016 Oct 24. PMID: 27789120
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Allergic Rhinitis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-4 downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Bacillus coagulans
Diseases : C-Reactive Protein, Dysbiosis, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Microbiota
[+]

Dark chocolate attenuates intracellular pro-inflammatory reactivity to acute psychosocial stress in men.Apr 27, 2016

Pubmed Data : Brain Behav Immun. 2016 Apr 28. Epub 2016 Apr 28. PMID: 27091601
Article Published Date : Apr 27, 2016
Study Type : Human Study
Additional Links
Substances : Chocolate
Diseases : Inflammation, Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, MicroRNA modulator
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Effect of B vitamins supplementation on cardio-metabolic factors in patients with stable coronary artery disease.Dec 31, 2019

Pubmed Data : Asia Pac J Clin Nutr. 2020 ;29(2):245-252. PMID: 32674231
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-6
Diseases : Coronary Artery Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Hypolipidemic, Interleukin-10 upregulation, Interleukin-1 beta downregulation
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Effect of butylphthalide on serum CRP, PARK7, NT-3 and neurological function in patients with acute cerebral infarction.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2021 ;13(9):10388-10395. Epub 2021 Sep 15. PMID: 34650707
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Celery Oil
Diseases : Stroke
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Neuroprotective Agents
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Effects of Pelargonium sidoides extract vs roxithromycin on chemokine levels in nasal secretions of patients with uncomplicated acute rhinosinusitis.Jan 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Laryngoscope Investig Otolaryngol. 2021 Feb ;6(1):25-33. Epub 2020 Dec 21. PMID: 33614926
Article Published Date : Jan 31, 2021
Study Type : Human Study
Additional Links
Substances : Germanium
Diseases : Rhinosinusitis: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-8 downregulation
[+]

Effects of photobiomodulation on interleukin-10 and nitrites in individuals with relapsing-remitting multiple sclerosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2020 ;15(4):e0230551. Epub 2020 Apr 7. PMID: 32255785
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Multiple Sclerosis
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Electroacupuncture for acute ischemic stroke and its effect on plasma levels of IL-17 and IL-10.Aug 11, 2022

Pubmed Data : Zhongguo Zhen Jiu. 2022 Aug 12 ;42(8):849-52. PMID: 35938325
Article Published Date : Aug 11, 2022
Study Type : Human Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
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Electroacupuncture may reduce the severity of acute pancreatitis by inducing anti-inflammatory effects and reducing the time to re-feeding.Mar 31, 2015

Pubmed Data : Acupunct Med. 2015 Apr ;33(2):115-20. Epub 2014 Dec 17. PMID: 25520280
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Pancreatitis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
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Ginkgo biloba extract attenuates the disruption of pro- and anti-inflammatory balance of peripheral blood in arsenism patients.Nov 30, 2022

Pubmed Data : Biol Trace Elem Res. 2022 Dec ;200(12):4967-4976. Epub 2022 Jan 22. PMID: 35064870
Article Published Date : Nov 30, 2022
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Arsenic Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
Additional Keywords : Plant Extracts
Problem Substances : Arsenic
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High-dose vitamin D might be useful in promoting an anti-inflammatory state in RRMS patients.Sep 24, 2015

Pubmed Data : Neuroimmunomodulation. 2015 Sep 25. Epub 2015 Sep 25. PMID: 26401986
Article Published Date : Sep 24, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
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L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.Feb 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Feb 7 ;11(2). Epub 2019 Feb 7. PMID: 30736479
Article Published Date : Feb 06, 2019
Study Type : Human Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Athletic Performance, Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2016 Feb 28 ;115(4):567-75. Epub 2016 Jan 15. PMID: 26769562
Article Published Date : Feb 27, 2016
Study Type : Human Study
Additional Links
Substances : Lactobacillus Acidophilus
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Lactobacillus brevis KB290 and β-carotene improves minor IBS diarrhoea-like symptoms and inflammatory status in healthy volunteers. Apr 08, 2017

Pubmed Data : Int J Food Sci Nutr. 2017 Apr 9:1-14. Epub 2017 Apr 9. PMID: 28391736
Article Published Date : Apr 08, 2017
Study Type : Human Study
Additional Links
Substances : B-Carotene, Lactobacillus Brevis
Diseases : Diarrhea: IBS associated, Irritable Bowel Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation
Additional Keywords : Anti-Inflammatory Agents, B-Carotene, Diarrhea: IBS associated, Gastrointestinal Agents, Interleukin-10 upregulation, irritable bowel syndrome, Lactobacillus Brevis
[+]

Lactobacillus plantarum DR7 improved upper respiratory tract infections .May 31, 2019

Pubmed Data : J Dairy Sci. 2019 Jun ;102(6):4783-4797. Epub 2019 Apr 4. PMID: 30954261
Article Published Date : May 31, 2019
Study Type : Human Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Upper Respiratory Infections
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunostimulatory, Interleukin-10 upregulation, Interleukin-4 upregulation
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Olive fruit and almond skin extract seems to protect LDL from oxidation and to prevent inflammatory status in moderately hypercholesterolemic subjects.Aug 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2020 Aug 18. Epub 2020 Aug 18. PMID: 32816626
Article Published Date : Aug 17, 2020
Study Type : Human Study
Additional Links
Substances : Almond, Olive
Diseases : Hypercholesterolemia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Omega 3 supplementation can regulate inflammatory states in gas station workers.Mar 12, 2020

Pubmed Data : J Interferon Cytokine Res. 2020 Mar 13. Epub 2020 Mar 13. PMID: 32176565
Article Published Date : Mar 12, 2020
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Photobiomodulation improves serum cytokine response in mild to moderate COVID-19.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2022 ;13:929837. Epub 2022 Jul 8. PMID: 35874678
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Potential modulation of inflammation by probiotic and omega-3 supplementation in elderly with chronic low-grade inflammation.Sep 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Sep 27 ;14(19). Epub 2022 Sep 27. PMID: 36235651
Article Published Date : Sep 26, 2022
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Probiotics
Diseases : C-Reactive Protein, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Probiotic NVP-1703 alleviates allergic rhinitis by inducing IL-10 expression.May 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 May 15 ;12(5). Epub 2020 May 15. PMID: 32429063
Article Published Date : May 14, 2020
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Longum , Lactobacillus plantarum, Probiotics
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
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Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis.Mar 31, 2014

Pubmed Data : Nutrition. 2014 Apr ;30(4):430-5. Epub 2013 Dec 17. PMID: 24355439
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Lactobacillus casei
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Probiotics have a favorable effect on immune status in multiple sclerosis patients. Jun 01, 2011

Pubmed Data : Mult Scler. 2011 Jun;17(6):743-54. Epub 2011 Mar 3. PMID: 21372112
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Multiple Sclerosis, Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation, Interleukin-4 upregulation
[+]

Propolis as an adjuvant in the healing of human diabetic foot wounds.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2019 ;2019:2507578. Epub 2019 Sep 12. PMID: 31612147
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Bee Propolis
Diseases : Diabetic Complications, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Glutathione Upregulation , Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Regular shiitake mushroom consumption resulted in improved immunity.Dec 31, 2014

Pubmed Data : J Am Coll Nutr. 2015 ;34(6):478-87. Epub 2015 Apr 11. PMID: 25866155
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Shiitake Mushroom
Diseases : C-Reactive Protein, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunostimulatory, Interleukin-10 upregulation, Interleukin-4 upregulation
[+]

Significant immunomodulatory and hepatoprotective impacts of Silymarin in MS patients.Apr 28, 2021

Pubmed Data : Int Immunopharmacol. 2021 Apr 29 ;97:107715. Epub 2021 Apr 29. PMID: 33933848
Article Published Date : Apr 28, 2021
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation
[+]

The effectiveness of BIFIFORM KIDS in the prevention of the incidence of acute respiratory infections in children.Dec 31, 2021

Pubmed Data : Vopr Pitan. 2022 ;91(4):97-106. Epub 2022 Jul 1. PMID: 36136951
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Upper Respiratory Infections
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
Additional Keywords : Risk Reduction
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The effects of saffron in conjunction with concurrent training on body composition, glycaemic status, and inflammatory markers.Jan 08, 2022

Pubmed Data : Br J Clin Pharmacol. 2022 Jan 9. Epub 2022 Jan 9. PMID: 35001410
Article Published Date : Jan 08, 2022
Study Type : Human Study
Additional Links
Substances : Saffron
Diseases : Diabetes Mellitus: Type 2
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The present study provides evidence that Diabetea tea has hypoglycemic and antihyperlipidemic properties.Dec 23, 2016

Pubmed Data : J Ethnopharmacol. 2016 Dec 24 ;194:1069-1077. Epub 2016 Oct 27. PMID: 27989874
Article Published Date : Dec 23, 2016
Study Type : Human Study
Additional Links
Substances : Black Tea
Diseases : Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-8 downregulation
Additional Keywords : BLACK TEA, Diabetes mellitus: Type 2, Hypoglycemic Agents, Hypolipidemic, Inflammation, Plant Extracts
[+]

Vitamin D has the potential of serving as a safe and effective adjuvant to oral nifedipine in treating women with preeclampsia against hypertension.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:865. Epub 2017 Nov 24. PMID: 29225576
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pre-Eclampsia
Pharmacological Actions : Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin D supplementation can improve mood status and anti-inflammatory biomarkers in female diabetics with anxiety and vitamin D deficiency.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2019 ;10:17. Epub 2019 Feb 12. PMID: 30820304
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Anxiety, Diabetes Mellitus: Type 2, Vitamin D Deficiency
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Vitamin D supplementation could help reduce the occurrence of chronic tonsillitis in susceptible children.May 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 May 17 ;13(1):8014. Epub 2023 May 17. PMID: 37198277
Article Published Date : May 16, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Tonsillitis, Vitamin D Deficiency
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin D(3) reduces the inflammatory milieu in congestive heart failure patients and might serve as a new antiinflammatory agent for the future treatment of the disease.Apr 01, 2006

Pubmed Data : Am J Clin Nutr. 2006 Apr;83(4):754-9. PMID: 16600924
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Congestive Heart Failure, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Zataria multiflora extract influenced asthmatic patients by improving respiratory symptoms, pulmonary function tests and lung inflammation.Feb 28, 2022

Pubmed Data : J Ethnopharmacol. 2022 Mar 1 ;285:114888. Epub 2021 Dec 1. PMID: 34863879
Article Published Date : Feb 28, 2022
Study Type : Human Study
Additional Links
Substances : Zataria multiflora
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Honeys with anti-inflammatory capacity can alter the elderly gut microbiota in an ex vivo gut model.Oct 29, 2022

Pubmed Data : Food Chem. 2022 Oct 30 ;392:133229. Epub 2022 May 18. PMID: 35679723
Article Published Date : Oct 29, 2022
Study Type : Human In Vitro
Additional Links
Substances : Honey
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Anti-tumor activity of arjunolic acid against ehrlich ascites carcinoma cells.Jul 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug ;82:28-34. Epub 2016 May 3. PMID: 27470335
Article Published Date : Jul 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Breast Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Apoptotic, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoidan from Fucus vesiculosus inhibits inflammatory response.May 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2023 May 17 ;21(5). Epub 2023 May 17. PMID: 37233496
Article Published Date : May 16, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

The neuroprotection of verbascoside in Alzheimer's disease mediated through mitigation of neuroinflammation.Mar 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Mar 29 ;14(7). Epub 2022 Mar 29. PMID: 35406030
Article Published Date : Mar 28, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Verbascoside
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) upregulation
[+]

The immunomodulatory activity of Punica granatum peel extract increases the lifespan of mice with lethal sepsis.Dec 31, 2022

Pubmed Data : J Immunol Res. 2023 ;2023:2868707. Epub 2023 Aug 16. PMID: 37621924
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Immunomodulatory, Interleukin-10 upregulation
[+]

6-gingerol alleviates inflammatory injury in DSS-induced ulcerative colitis.Jul 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Palliat Med. 2020 Jul 14. Epub 2020 Jul 14. PMID: 32692218
Article Published Date : Jul 13, 2020
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor
[+]

8 and 10-Gingerol reduces urothelial damage in ifosfamide-induced hemorrhagic cystitis.Feb 26, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Feb 27. Epub 2023 Feb 27. PMID: 36843129
Article Published Date : Feb 26, 2023
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Cystitis: Hemorrhagic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Accelerated skeletal muscle recovery after in vivo polyphenol administration.Aug 31, 2012

Pubmed Data : J Nutr Biochem. 2012 Sep ;23(9):1072-9. Epub 2011 Nov 12. PMID: 22079208
Article Published Date : Aug 31, 2012
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract, Polyphenols
Diseases : Muscle Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation
Additional Keywords : Muscle Regeneration
[+]

Acteoside promotes B cell-derived IL-10 production and ameliorates autoimmunity.Sep 30, 2022

Pubmed Data : J Leukoc Biol. 2022 Oct ;112(4):875-885. Epub 2022 May 31. PMID: 35638582
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Verbascoside
Diseases : Autoimmune Diseases, Rheumatoid Arthritis, Sjogren's Syndrome
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.Jul 22, 2019

Pubmed Data : Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID: 31334539
Article Published Date : Jul 22, 2019
Study Type : Animal Study
Additional Links
Substances : Mango leaf
Diseases : Inflammation, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor
Anti Therapeutic Actions : Western Diet
[+]

Administration of Lycium barbarum polysaccharides and capsaicin attenuate dextran sulfate sodium-induced ulcerative colitis symptoms.Feb 21, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Feb 22 ;23(5). Epub 2022 Feb 22. PMID: 35269566
Article Published Date : Feb 21, 2022
Study Type : Animal Study
Additional Links
Substances : Capsaicin, Goji
Diseases : Oxidative Stress, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Adrenal sympathetic nerve mediated the anti-inflammatory effect of electroacupuncture at ST25 acupoint in a model of sepsis.Oct 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Rec (Hoboken). 2022 Oct 27. Epub 2022 Oct 27. PMID: 36300612
Article Published Date : Oct 26, 2022
Study Type : Animal Study
Additional Links
Diseases : Sepsis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Aerobic exercise decreases lung inflammation by IgE decrement in an OVA mice model.May 31, 2017

Pubmed Data : Int J Sports Med. 2017 Jun ;38(6):473-480. Epub 2017 Apr 7. PMID: 28388779
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Asthma
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

Aerobic training and royal jelly improved inflammatory and regulatory factors of autoimmunity and reduced anxiety and depression.Jan 19, 2023

Pubmed Data : Mult Scler Relat Disord. 2023 Jan 20 ;70:104527. Epub 2023 Jan 20. PMID: 36696832
Article Published Date : Jan 19, 2023
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Brain Inflammation , Multiple Sclerosis
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-23 Downregulation, Transforming growth factor beta (TGF-β) inhibitor
[+]

Aloe vera gel suppressed Th2 immune responses in mice with food allergy.Feb 25, 2018

Pubmed Data : Biomed Pharmacother. 2018 Feb 26 ;101:201-210. Epub 2018 Feb 26. PMID: 29494957
Article Published Date : Feb 25, 2018
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Hypersensitivity
Pharmacological Actions : Interleukin-10 upregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
Additional Keywords : Aloe vera, Hypersensitivity, Polysaccharides
[+]

Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction.Jul 06, 2020

Pubmed Data : Toxicology. 2020 Jul 7 ;442:152536. Epub 2020 Jul 7. PMID: 32649955
Article Published Date : Jul 06, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Radiation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation
[+]

Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne.May 09, 2019

Pubmed Data : J Ethnopharmacol. 2019 May 10 ;235:460-471. Epub 2019 Feb 13. PMID: 30771518
Article Published Date : May 09, 2019
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Ameliorative effect of thymoquinone-loaded PLGA nanoparticles on chronic lung injury induced by repetitive intratracheal instillation of lipopolysaccharide.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:5511523. Epub 2021 May 28. PMID: 34136063
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Ameliorative effects of Moringa oleifera leaf extract on levofloxacin-induced hepatic toxicity.Feb 19, 2019

Pubmed Data : Drug Chem Toxicol. 2019 Feb 20:1-7. Epub 2019 Feb 20. PMID: 30782023
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Antibiotic Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation
Problem Substances : Fluoroquinolone Antibiotic, Levofloxacin
[+]

Amygdalin attenuates atherosclerosis and plays an anti-inflammatory roleDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:590929. Epub 2020 Oct 29. PMID: 33192531
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Amygdalin
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Analysis of protective effects of Rosa Roxburghii Tratt fruit polyphenols on lipopolysaccharide-induced acute lung injury.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2022 Dec ;10(12):4258-4269. Epub 2022 Aug 25. PMID: 36514748
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Rose
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Andrographolide attenuates inflammation due to intra-abdominal sepsis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm Res. 2023 ;16:4413-4423. Epub 2023 Oct 6. PMID: 37822531
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Andrographolide prevented type 1 diabetes by maintaining Th1/Th2/Th17 homeostasis.Jul 31, 2013

Pubmed Data : Int Immunopharmacol. 2013 Aug ;16(4):451-6. Epub 2013 May 23. PMID: 23707775
Article Published Date : Jul 31, 2013
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-2 Downregulation
[+]

Anti-inflammatory, anti-oxidant and anti-lipaemic effects of daily dietary coenzyme-Q10 supplement in a mouse model of metabolic syndrome.Apr 25, 2021

Pubmed Data : Antiinflamm Antiallergy Agents Med Chem. 2021 Apr 26. Epub 2021 Apr 26. PMID: 33906592
Article Published Date : Apr 25, 2021
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-malarial and cytokine-modulating effects of andrographolide in a murine model of malarial infection.Aug 31, 2019

Pubmed Data : Trop Biomed. 2019 Sep 1 ;36(3):776-791. PMID: 33597499
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Malaria
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 upregulation
[+]

Antioxidant activity of yogurt fermented at low temperature and its anti-inflammatory effect on DSS-induced colitis.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Anim Resour. 2019 Feb ;39(1):162-176. Epub 2019 Feb 28. PMID: 30882084
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Yoghurt
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation
[+]

Apigenin may be an alternative therapeutic option for prevention of sepsis-induced organ damage. May 31, 2016

Pubmed Data : Immunopharmacol Immunotoxicol. 2016 Jun ;38(3):228-237. PMID: 27144896
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway.Dec 31, 2022

Pubmed Data : Int Immunopharmacol. 2023 Jan ;114:109529. Epub 2022 Dec 6. PMID: 36481528
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Insulin Sensitizers, Interleukin-10 upregulation
[+]

Astaxanthin exerts different anti-inflammatory effects in female and male brains.Jan 29, 2016

Pubmed Data : J Sci Food Agric. 2016 Jan 30 ;96(2):615-8. Epub 2015 Feb 25. PMID: 25678261
Article Published Date : Jan 29, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Aging, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation
[+]

Baicalein may be an effective immunomodulator that attenuates overwhelming inflammatory responses in severe abdominal sepsis.Mar 29, 2022

Pubmed Data : Chin J Integr Med. 2022 Mar 30. Epub 2022 Mar 30. PMID: 35355199
Article Published Date : Mar 29, 2022
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalin regulates autophagy to interfere with small intestinal acute graft-versus-host disease.Jan 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2022 04 21 ;12(1):6551. Epub 2022 Apr 21. PMID: 35449393
Article Published Date : Jan 20, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Graft vs Host Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Beneficial effects of Thymus vulgaris extract in experimental autoimmune encephalomyelitis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:2100-2108. Epub 2018 Nov 26. PMID: 30551467
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thyme
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Berberine ameliorates depression-like behavior.Sep 10, 2022

Pubmed Data : Phytother Res. 2022 Sep 11. Epub 2022 Sep 11. PMID: 36089660
Article Published Date : Sep 10, 2022
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine exerted a superior anti-arthritic effect and the mechanism maybe involve the balance between Treg and Th17 cells.Mar 05, 2017

Pubmed Data : Biomed Pharmacother. 2017 Mar 6 ;89:887-893. Epub 2017 Mar 6. PMID: 28282791
Article Published Date : Mar 05, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.Aug 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Aug 7 ;25(29):3956-3971. PMID: 31413530
Article Published Date : Aug 06, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Berberine protests the heart from ischemic reperfusion injury. May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Arch. 2021 Jun ;75(3):174-179. PMID: 34483445
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine treatment reduced hepatic injury caused by concanavalin A.Dec 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2017 Dec 28 ;23:6150-6161. Epub 2017 Dec 28. PMID: 29283990
Article Published Date : Dec 27, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Hepatitis: Autoimmune
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Berberine, Hepatitis: Autoimmune, Hepatoprotective, Interferon Gamma Reducer
Problem Substances : Concanavalin A
[+]

Betulinic acid derivative BA5 had a potent anti-inflammatory activity on a model of parasite-driven heart disease.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:1257. Epub 2019 Jun 11. PMID: 31244833
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Chagas Disease, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A attenuates zymosan-induced arthritis in mice similarly to 17-β estradiol.Nov 30, 2020

Pubmed Data : Inflamm Res. 2020 Dec ;69(12):1245-1256. Epub 2020 Sep 25. PMID: 32975609
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Ovariectomy-Induced Changes
[+]

Bixin attenuates experimental autoimmune encephalomyelitis. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2020 ;11:593368. Epub 2020 Dec 9. PMID: 33362775
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Bixin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Boric acid attenuates AOM-induced colorectal cancer.Sep 28, 2023

Pubmed Data : Biol Trace Elem Res. 2023 Sep 29. Epub 2023 Sep 29. PMID: 37770673
Article Published Date : Sep 28, 2023
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

C60 fullerenes could be represented as a promising therapeutic agent in the treatment of obesity and its related complications.Nov 30, 2018

Pubmed Data : Int J Obes (Lond). 2018 Dec ;42(12):1987-1998. Epub 2018 Jan 30. PMID: 30401827
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Carbon 60
Diseases : High Fat Diet, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation
[+]

Caffeic acid phenethyl ester protects against photothrombotic cortical ischemic injury in mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2018 Jan ;22(1):101-110. Epub 2017 Dec 22. PMID: 29302217
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Caffeic acid phenethyl ester, Heme oxygenase-1 up-regulation, Ischemia
[+]

Camel milk attenuates rheumatoid arthritis in animals. Sep 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 Sep 20 ;43(2):540-552. Epub 2017 Sep 20. PMID: 28930753
Article Published Date : Sep 19, 2017
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cannabidiol can possibly be used as a therapeutic agent for treatment of type 1 diabetes.Dec 31, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropharmacology. 2008 Jan ;54(1):244-9. Epub 2007 Jul 17. PMID: 17714746
Article Published Date : Dec 31, 2007
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation
[+]

Cannabidiol-rich non-psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms.Apr 30, 2023

Pubmed Data : Phytother Res. 2023 May ;37(5):1924-1937. Epub 2022 Dec 30. PMID: 36583304
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Centella asiatica can be useful in the management of diabetic complications.Feb 28, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar 1 ;101:447-457. Epub 2018 Mar 1. PMID: 29501767
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 upregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chinese skullcap contains a compound, Baicalin, which may favorably alter the TH1/TH2 balance in asthma. Sep 01, 2009

Pubmed Data : Zhong Yao Cai. 2009 Sep;32(9):1407-10. PMID: 20034219
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Chrysin is immunomodulatory and anti-inflammatory against complete Freund's adjuvant-induced arthritis.Apr 11, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2023 Apr 12 ;15(4). Epub 2023 Apr 12. PMID: 37111711
Article Published Date : Apr 11, 2023
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation
[+]

Chrysin, a 5,7-dihydroxyflavone restrains inflammatory arthritis.Jul 31, 2023

Pubmed Data : Inflammopharmacology. 2023 Aug ;31(4):1863-1878. Epub 2023 Apr 21. PMID: 37083920
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Arthritis, Oxidative Stress
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation
[+]

Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice.Dec 31, 2020

Pubmed Data : Transl Neurosci. 2021 Jan 1 ;12(1):469-481. Epub 2021 Nov 30. PMID: 34900345
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin and vitamin C attenuate gentamicin-induced nephrotoxicity.Dec 27, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2022 Dec 28 ;13(1). Epub 2022 Dec 28. PMID: 36676974
Article Published Date : Dec 27, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin, Vitamin C
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Interleukin-10 upregulation, Renoprotective
[+]

Curcumin can reduce the degree of severity of acute lung injury and uncontrolled inflammation.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 May ;125:109946. Epub 2020 Jan 28. PMID: 32004976
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Lung Injury: Acute, Respiratory Distress Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

Curcumin suppresses titanium particle-induced inflammation by regulating macrophage polarization.Dec 31, 2016

Pubmed Data : Front Immunol. 2017 ;8:55. Epub 2017 Jan 31. PMID: 28197150
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin-added whey protein positively modulates skeletal muscle inflammation and oxidative damage after exhaustive exercise.Nov 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 19 ;14(22). Epub 2022 Nov 19. PMID: 36432591
Article Published Date : Nov 18, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin, Whey
Diseases : Inflammation, Muscle Soreness: Exercise-Induced, Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:362-372. Epub 2018 Apr 24. PMID: 29669302
Article Published Date : Jun 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Inflammation, Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Hepatoprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Deuterium-depleted water as adjuvant therapeutic agent for treatment of diet-induced obesity.Dec 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Dec 19 ;25(1). Epub 2019 Dec 19. PMID: 31861678
Article Published Date : Dec 18, 2019
Study Type : Animal Study
Additional Links
Substances : Water: Deuterium Depleted
Diseases : Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Differential relieving effects of shikonin and its derivatives on inflammation and mucosal barrier damage caused by ulcerative colitis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2021 ;9:e10675. Epub 2021 Jan 7. PMID: 33505807
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Shikonin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-10 upregulation
[+]

Echinacoside improves neurobehavioral symptoms in Parkinson's disease.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2021 ;17:1779-1792. Epub 2021 Jun 3. PMID: 34113108
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effect of berberine on atherosclerosis and gut microbiota modulation and their correlation in high-fat diet-fed ApoE-/- mice.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:223. Epub 2020 Mar 13. PMID: 32231564
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Atherosclerosis, High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Effect of black seeds on inflammatory and immunomodulatory markers in Plasmodium berghei.Jul 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Biochem. 2022 Jul 14:e14300. Epub 2022 Jul 14. PMID: 35833536
Article Published Date : Jul 13, 2022
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Malaria
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease.Dec 31, 2019

Pubmed Data : Vopr Pitan. 2020;89(5):6-16. Epub 2020 Sep 20. PMID: 33211913
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Carnosine
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-1 alpha downregulation
[+]

Effect of Lactobacillus fermentum MCC2760-based probiotic curd on hypercholesterolemic C57BL6 mice.Mar 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2021 Mar 23 ;6(11):7701-7710. Epub 2021 Mar 12. PMID: 33778280
Article Published Date : Mar 22, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Hypercholesterolemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of 1, 25-dihydroxy vitamin D3 on clinical symptoms, pro-inflammatory and inflammatory cytokines in calves with experimental pneumonia.Sep 30, 2020

Pubmed Data : Res Vet Sci. 2020 Oct ;132:186-193. Epub 2020 May 17. PMID: 32593863
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Pneumonia
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of dietary chlorogenic acid on intestinal barrier function and the inflammatory response in broilers during lipopolysaccharide-induced immune stress.Apr 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Poult Sci. 2023 May ;102(5):102623. Epub 2023 Mar 4. PMID: 36972676
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of Lactobacillus plantarum strain OLL2712 culture conditions on the anti-inflammatory activities for murine immune cells and obese and type 2 diabetic mice.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Appl Environ Microbiol. 2017 04 1 ;83(7). Epub 2017 Mar 17. PMID: 28087537
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Effects of ursolic acid on oxidative stress and inflammatory factors in a rat model of AR after PM2.5 exposure.Jul 06, 2022

Pubmed Data : Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Jul 7 ;57(7):860-867. PMID: 35866280
Article Published Date : Jul 06, 2022
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Allergic Rhinitis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation
[+]

EGCG improved lung damage in P. aeruginosa infection by inhibiting the production.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2022 ;13:874354. Epub 2022 Apr 25. PMID: 35547130
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Lung Damage, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation, Quorum Sensing Inhibition, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Electroacupuncture at Zusanli alleviates sepsis. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:6706622. Epub 2022 Jun 10. PMID: 35722155
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Sepsis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Electroacupuncture pre-treatment alleviates cerebral ischemic injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2019 ;13:537. Epub 2019 Dec 6. PMID: 31866829
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Cerebral Ischemia
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Enteral exposure to P histicola suppresses arthritis via mucosal regulation.Jan 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Rheumatol. 2016 12 ;68(12):2878-2888. PMID: 27337150
Article Published Date : Jan 11, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Probiotics
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

Epigallocatechin gallate ameliorates airway inflammation by regulating Treg/Th17 imbalance in an asthmatic mouse model.Apr 24, 2019

Pubmed Data : Int Immunopharmacol. 2019 Apr 25 ;72:422-428. Epub 2019 Apr 25. PMID: 31030098
Article Published Date : Apr 24, 2019
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation
[+]

Evening primrose/hemp seed oil was able to reduce the severity of autoimmune encephalomyelitis and inhibited the development of the disease.Apr 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Allergy Asthma Immunol. 2020 Apr 16 ;19(2):183-192. Epub 2020 Apr 16. PMID: 32372631
Article Published Date : Apr 15, 2020
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil, Hemp Seed
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-10 upregulation
[+]

Exercise training improves the IL-10/TNF-α cytokine balance in the gastrocnemius of rats with heart failure.Sep 06, 2017

Pubmed Data : Braz J Phys Ther. 2017 Sep 7. Epub 2017 Sep 7. PMID: 28939262
Article Published Date : Sep 06, 2017
Study Type : Animal Study
Additional Links
Diseases : Heart Failure, Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fermented H erinaceus juice may be used as one of the food-based health-promoting supplement to manage diabetes mellitus along with medication.Dec 31, 2017

Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18765699. PMID: 29619846
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus fermentum, Lion's Mane (Hericium Erinaceus)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Ferulic acid improves depressive-like behaviour.Jan 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jan 24 ;20(3). Epub 2019 Jan 24. PMID: 30678337
Article Published Date : Jan 23, 2019
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ferulic Acid reduces amyloid beta mediated neuroinflammation.Dec 31, 2022

Pubmed Data : PLoS One. 2023 ;18(8):e0290249. Epub 2023 Aug 17. PMID: 37590236
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Flaxseed oligosaccharides alleviate DSS-induced colitis.Aug 27, 2020

Pubmed Data : Food Funct. 2020 Aug 28. Epub 2020 Aug 28. PMID: 32856645
Article Published Date : Aug 27, 2020
Study Type : Animal Study
Additional Links
Substances : Flaxseed, Oligosaccharides
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

G. gargal extract augments the lung population of regulatory T cells and ameliorates allergic inflammation.Dec 19, 2017

Pubmed Data : J Med Food. 2017 Dec 20. Epub 2017 Dec 20. PMID: 29261008
Article Published Date : Dec 19, 2017
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms
Diseases : Asthma: Bronchial
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, interleukin-13 down-regulation
[+]

Garden cress extracts have significant hepatoprotective activity in animals. Dec 02, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):501. Epub 2016 Dec 3. PMID: 27912738
Article Published Date : Dec 02, 2016
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum)
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.Feb 04, 2021

Pubmed Data : Eur J Pharmacol. 2021 Feb 5 ;892:173734. Epub 2020 Nov 18. PMID: 33220272
Article Published Date : Feb 04, 2021
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Aging: Brain , Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genistein prevents hypoxia-induced cognitive dysfunctions by ameliorating oxidative stress and inflammation in the hippocampus.Mar 18, 2021

Pubmed Data : Neurotox Res. 2021 Mar 19. Epub 2021 Mar 19. PMID: 33740236
Article Published Date : Mar 18, 2021
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Hypoxia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2019 Apr ;83(4):675-683. Epub 2018 Dec 20. PMID: 30570395
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Ginsenoside CK inhibits obese insulin resistance by activating PPARγ to interfere with macrophage activation.May 25, 2021

Pubmed Data : Microb Pathog. 2021 May 26 ;157:105002. Epub 2021 May 26. PMID: 34051328
Article Published Date : May 25, 2021
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Inflammation, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rb1 interfered with macrophage activation by activating PPARγ to inhibit insulin resistance in obesity.Mar 29, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Mar 30 ;28(7). Epub 2023 Mar 30. PMID: 37049846
Article Published Date : Mar 29, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetes Mellitus: Type 2, Inflammation, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers, Interleukin-10 upregulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rg3 treats acute radiation proctitis through the TLR4/MyD88/NF-κB pathway and regulation of intestinal flora.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Infect Microbiol. 2022 ;12:1028576. Epub 2023 Jan 6. PMID: 36683687
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Proctitis, Radiation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Radioprotective
[+]

Glabridin prevents doxorubicin-induced cardiotoxicity through gut microbiota modulation and colonic macrophage polarization.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:107. Epub 2019 Feb 15. PMID: 30833897
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Isoflavones
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Chemoprotective Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Glycyrrhizin attenuates Salmonella typhimurium-induced tissue injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2021 ;8:648698. Epub 2021 Jun 22. PMID: 34239908
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Glycyrrhizin
Diseases : Dysbiosis, Salmonella Infections
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Heat-killed Lacticaseibacillus paracasei repairs lipopolysaccharide-induced intestinal epithelial barrier damage.Apr 03, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Apr 4 ;15(7). Epub 2023 Apr 4. PMID: 37049598
Article Published Date : Apr 03, 2023
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Lipopolysaccharide-Induced Toxicity, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Heat-killed probiotic regulates the body's regulatory immunity to attenuate subsequent experimental autoimmune arthritis.Oct 19, 2019

Pubmed Data : Immunol Lett. 2019 Oct 20. Epub 2019 Oct 20. PMID: 31644891
Article Published Date : Oct 19, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri, Probiotics
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Hemp seed oil and evening primrose oil has beneficial effects on the repair of myelin.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2019 Feb ;14(1):36-45. PMID: 30936931
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil, Hemp Seed
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Additional Keywords : Gene Expression Regulation, Remyelination
[+]

Hepatosplenic protective actions of Spirulina platensis and matcha green tea against Schistosoma mansoni infection.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2021 ;8:650531. Epub 2021 Apr 30. PMID: 33996977
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Green Tea, Spirulina
Diseases : Schistosomiasis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, interleukin-13 down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Honokiol-rich Magnolia officinalis bark extract attenuates trauma-induced neuropathic pain.Jul 27, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Jul 28 ;12(8). Epub 2023 Jul 28. PMID: 37627513
Article Published Date : Jul 27, 2023
Study Type : Animal Study
Additional Links
Substances : Honokiol, Magnolia
Diseases : Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Humulus japonicus has a beneficial effect on cognitive impairment and neuroinflammation induced by systemic inflammation and on amnesia.Jul 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2022 Jul 19 ;38(1):21. Epub 2022 Jul 19. PMID: 35854340
Article Published Date : Jul 18, 2022
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation, Neuroprotective Agents
[+]

Hydrogen-rich water protects against chronic ethanol-induced liver injury.Jul 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2017 Jul 21 ;23(27):4920-4934. PMID: 28785146
Article Published Date : Jul 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hydrogen Water
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis.Dec 31, 2020

Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2021 04 1 ;320(4):G450-G463. Epub 2021 Jan 13. PMID: 33439102
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation
[+]

Icariin improves cutaneous wound healing in streptozotocin-induced diabetes.Jan 31, 2022

Pubmed Data : J Tissue Viability. 2022 Feb ;31(1):197-206. Epub 2021 Sep 21. PMID: 34565677
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Diabetic Complications, Wound Healing: Delayed
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Identification of a Lactobacillus plantarum strain that ameliorates chronic inflammation and metabolic disorders in obese and type 2 diabetic mice.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dairy Sci. 2016 Feb ;99(2):933-946. Epub 2015 Dec 10. PMID: 26686731
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Diabetes Mellitus: Type 2, Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Immunomodulatory effect of curcumin on hepatic cirrhosis in experimental rats.Mar 24, 2020

Pubmed Data : J Food Biochem. 2020 Mar 25:e13219. Epub 2020 Mar 25. PMID: 32215945
Article Published Date : Mar 24, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Cirrhosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) inhibitor
[+]

In vivo and in vitro anti-inflammatory effects of water-soluble polysaccharide from Arctium lappa.Aug 14, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 15 ;135:717-724. Epub 2019 May 23. PMID: 31129217
Article Published Date : Aug 14, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

In vivo evaluation of the protective effects of arjunolic acid against lipopolysaccharide-induced septic myocardial injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2022 ;10:e12986. Epub 2022 Feb 16. PMID: 35190789
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-10 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Inonotus obliquus polysaccharide protects against adverse pregnancy caused by Toxoplasma gondii infection.Nov 10, 2019

Pubmed Data : Int J Biol Macromol. 2019 Nov 11. Epub 2019 Nov 11. PMID: 31726135
Article Published Date : Nov 10, 2019
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents, Immunomodulatory, Interleukin-10 upregulation, NF-kappaB Inhibitor
[+]

Isogarcinol is a promising immunosuppressive agent for treating psoriasis.Jan 31, 2017

Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID: 28081600
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Lipopolysaccharide-Induced Toxicity, Psoriasis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-23 Downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Kgengwe seeds increase circulating levels of IL-10 and EPO. Jan 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Appl Physiol Nutr Metab. 2021 Feb ;46(2):169-177. Epub 2020 Aug 26. PMID: 32846097
Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Substances : Watermelon
Diseases : Inflammation
Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Korean Red Ginseng alleviates neuroinflammation and promotes cell survival.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2020 Jul ;44(4):593-602. Epub 2019 May 24. PMID: 32617039
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L. fermentum PC1 could prove to be a valuable therapeutic agent in the management of rheumatoid arthritis.Apr 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Apr 5 ;11(4). Epub 2019 Apr 5. PMID: 30959746
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-4 upregulation
[+]

L. sakei S1 may inhibit the NF-κB pathway and be used as functional food to treat colitis.Oct 12, 2019

Pubmed Data : J Microbiol Biotechnol. 2019 Oct 13. Epub 2019 Oct 13. PMID: 31635441
Article Published Date : Oct 12, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus sakei
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus fermentum could act as potential probiotic for lifestyle-related disorders such as obesity, diabetes, and metabolic syndrome.Feb 10, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Probiotics Antimicrob Proteins. 2021 Feb 11. Epub 2021 Feb 11. PMID: 33575913
Article Published Date : Feb 10, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Diabetes Mellitus: Type 2, High Fat Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Lactobacillus fermentum CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway.Jul 04, 2021

Pubmed Data : Food Funct. 2021 Jul 5 ;12(13):6029-6044. PMID: 34037025
Article Published Date : Jul 04, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation
Problem Substances : Lead
[+]

Lactobacillus fermentum species ameliorate dextran sulfate sodium-induced colitis.Apr 02, 2019

Pubmed Data : Gut Microbes. 2019 Apr 3:1-16. Epub 2019 Apr 3. PMID: 30939976
Article Published Date : Apr 02, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

Lactobacillus helveticus NS8 improves behavioural, cognitive, and biochemical aberrations caused by chronic restraint stress.Dec 02, 2015

Pubmed Data : Neuroscience. 2015 Dec 3 ;310:561-77. Epub 2015 Sep 25. PMID: 26408987
Article Published Date : Dec 02, 2015
Study Type : Animal Study
Additional Links
Substances : Lactobacillus helveticus, Probiotics
Diseases : Anxiety, Depression
Pharmacological Actions : Antidepressive Agents, Interleukin-10 upregulation
Additional Keywords : Gut-brain Axis, Superiority of Natural Substances versus Drugs
[+]

Lactobacillus plantarum and Bifidobacterium bifidum alleviate dry eye.Mar 20, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2021 Mar 21 ;12(6):2489-2497. Epub 2021 Mar 3. PMID: 33656499
Article Published Date : Mar 20, 2021
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium Bifidum, Lactobacillus plantarum
Diseases : Dry Eye Syndromes
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus plantarum HNU082 supplementation relieves ulcerative colitis.Nov 01, 2022

Pubmed Data : Microbiol Spectr. 2022 Nov 2:e0165122. Epub 2022 Nov 2. PMID: 36321893
Article Published Date : Nov 01, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Lactobacillus reuteri CCFM1175 and Lactobacillus paracasei CCFM1176 could prevent capsaicin-induced ileal and colonic Injuries.Jul 31, 2023

Pubmed Data : Probiotics Antimicrob Proteins. 2023 Aug ;15(4):797-812. Epub 2023 Jun 14. PMID: 37314694
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei, Lactobacillus reuteri
Diseases : Diarrhea, Gastrointestinal Complaints
Pharmacological Actions : Anti-Inflammatory Agents, Beta-Endorphin Enhancer, Gastroprotective, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus reuteri FYNLJ109L1 attenuating metabolic syndrome.Sep 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Sep 2 ;10(9). Epub 2021 Sep 2. PMID: 34574191
Article Published Date : Sep 01, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Lactobacillus sakei WIKIM30 ameliorates atopic dermatitis-like skin lesions.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1905. Epub 2018 Aug 14. PMID: 30154801
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lactobacillus sakei
Diseases : Atopic Dermatitis
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Lactoferrin peptides limit pro-inflammatory signaling and cytokine production by LPS-activated human macrophages.Jul 20, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Jul 21 ;21(14). Epub 2020 Jul 21. PMID: 32708308
Article Published Date : Jul 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

LED treatment ameliorates allergic lung inflammation in experimental model of asthma.Apr 17, 2017

Pubmed Data : J Biophotonics. 2017 Apr 18. Epub 2017 Apr 18. PMID: 28417574
Article Published Date : Apr 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Asthma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interferon-gamma (IFN-gamma) inducer, Interleukin-10 upregulation
[+]

LED treatment reduced the release of IL-6 and TNF-α and increased the release of IL-10, improving the inflammatory response in OVX rats.Dec 31, 2015

Pubmed Data : Lasers Med Sci. 2016 Jan ;31(1):33-40. Epub 2015 Oct 27. PMID: 26507001
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Tendon Injury
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lentinan attenuates damage of the small intestinal mucosa, liver, and lung in mice with gut-origin sepsis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2021 ;2021:2052757. Epub 2021 Nov 8. PMID: 34790828
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Shitake Mushroom
Diseases : Inflammation, Sepsis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Light-emitting diode therapy reduces persistent inflammatory pain.Mar 17, 2016

Pubmed Data : Neuroscience. 2016 Mar 18 ;324:485-495. Epub 2016 Mar 18. PMID: 27001179
Article Published Date : Mar 17, 2016
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Pain
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Interleukin-10 upregulation, Superoxide Dismutase Up-regulation
[+]

Ligustrazine could alleviate the airway inflflammation in the neutrophilic asthma mice model.Apr 30, 2018

Pubmed Data : Chin J Integr Med. 2018 May ;24(5):353-358. Epub 2017 Oct 30. PMID: 29086220
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2023 Mar ;47(2):210-217. Epub 2021 Apr 22. PMID: 36926614
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Aging, Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Loquat seed has immunomodulatory properties in allergic dermatitis. Jan 01, 2010

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2010;56(2):145-9. PMID: 20495297
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Loquat Seeds
Diseases : Allergies, Dermatitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory, Interferon-gamma (IFN-gamma) inducer, Interleukin-10 upregulation, Interleukin-2 upregulation, Interleukin-4 downregulation
Additional Keywords : Plant Extracts
[+]

Low level laser therapy reduces the development of lung inflammation induced by formaldehyde exposure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(11):e0142816. Epub 2015 Nov 16. PMID: 26569396
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Formaldehyde Toxicity, Lung Inflammation
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Formaldehyde
[+]

Low molecular weight fucoidan could be used to ameliorate the occurrence and development of atherosclerosis.Jun 11, 2018

Pubmed Data : Int J Biol Macromol. 2018 Jun 12. Epub 2018 Jun 12. PMID: 29906534
Article Published Date : Jun 11, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Low molecular-weight fucoidan can be used as a skin-protective remedy for photoaging.Aug 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2018 Aug 18 ;16(8). Epub 2018 Aug 18. PMID: 30126169
Article Published Date : Aug 17, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Photoprotective
[+]

Lupeol enhances wound healing in streptozotocin-induced hyperglycaemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:3182627. Epub 2019 May 9. PMID: 31210838
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lupeol
Diseases : Diabetic Complications, Hyperglycemia, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury.Jul 07, 2021

Pubmed Data : Int Immunopharmacol. 2021 Jul 8 ;99:107914. Epub 2021 Jul 8. PMID: 34246059
Article Published Date : Jul 07, 2021
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Luteolin prevents intestinal mucositis induced by irinotecan.Jan 23, 2020

Pubmed Data : Br J Pharmacol. 2020 Jan 24. Epub 2020 Jan 24. PMID: 31976547
Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Chemotherapy-Induced Toxicity: Irinotecan, Drug-Induced Toxicity: Gastrointestinal, Mucositis
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Irinotecan
[+]

Lycium barbarum lipid-based edible nanoparticles protect against experimental colitis.Dec 22, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Dec 23:110747. Epub 2019 Dec 23. PMID: 31924469
Article Published Date : Dec 22, 2019
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):455-464. PMID: 31070537
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-17 downregulation
Additional Keywords : Natural Substance/Drug Synergy
[+]

Manuka honey is effective in the treatment of chronic ulcer and preservation of mucosal glycoproteins.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:5413917. Epub 2017 Jan 19. PMID: 28250794
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Manuka Honey
Diseases : Gastric Ulcers
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Milk Kefir therapy reduces inflammation and alveolar bone loss on periodontitis in rats.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Jul ;139:111677. Epub 2021 May 6. PMID: 33965727
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Inflammation, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Modulation of pro-inflammatory and anti-inflammatory cytokines in the fat by an aloe gel-based formula.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Immune Netw. 2021 Apr ;21(2):e15. Epub 2021 Mar 25. PMID: 33996171
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Dysbiosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Molecular mechanism of astragaloside Ⅳ against atherosclerosis by regulating miR-17-5p and PCSK9/VLDLR signal pathway.Dec 31, 2021

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2022 Jan ;47(2):492-498. PMID: 35178994
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Momordica charantia polysaccharides alleviate diarrhea-predominant irritable bowel syndrome.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergol Immunopathol (Madr). 2022 ;50(3):62-70. Epub 2022 May 1. PMID: 35527657
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Bitter Melon
Diseases : Diarrhea, Inflammation, Irritable Bowel Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Moringa oleifera alcoholic extract protected stomach from bisphenol A-induced gastric ulcer.May 11, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2022 May 12. Epub 2022 May 12. PMID: 35554805
Article Published Date : May 11, 2022
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Bisphenol Toxicity, Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Bisphenol A
[+]

Moringa oleifera leaf polysaccharide alleviates experimental colitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:1055791. Epub 2022 Nov 10. PMID: 36438754
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation
Additional Keywords : Polysaccharides
[+]

Nano-celastrol represents a translatable therapeutic opportunity for treating diet-induced obesity in humans.Sep 27, 2019

Pubmed Data : J Control Release. 2019 Sep 28 ;310:188-197. Epub 2019 Aug 25. PMID: 31454532
Article Published Date : Sep 27, 2019
Study Type : Animal Study
Additional Links
Substances : Celastrol
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

Naringin attenuates cerebral ischemia-reperfusion injury.Dec 31, 2020

Pubmed Data : Transl Neurosci. 2021 Jan 1 ;12(1):190-197. Epub 2021 May 13. PMID: 34046215
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-8 downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Naringin improved sepsis-induced intestinal injury.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:50-58. Epub 2018 Apr 7. PMID: 29635128
Article Published Date : Jun 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effect of formononetin against traumatic brain injury.Sep 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:349-354. Epub 2018 Jul 11. PMID: 29966980
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effect of methanolic Ajwa seed extract on lipopolysaccharide-induced memory dysfunction and neuroinflammation.Feb 17, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2023 Feb 18 ;12(4). Epub 2023 Feb 18. PMID: 36840284
Article Published Date : Feb 17, 2023
Study Type : Animal Study
Additional Links
Substances : Dates
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Nobiletin alleviates cerebral ischemic-reperfusion injury via MAPK signaling pathway.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(9):5967-5977. Epub 2019 Sep 15. PMID: 31632564
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Novel ginsenoside monomer RT4 promotes colitis repair.Jun 22, 2023

Pubmed Data : Fundam Clin Pharmacol. 2023 Jun 23. Epub 2023 Jun 23. PMID: 37350460
Article Published Date : Jun 22, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Oral administration of banana lectin modulates cytokine profile and abundance of T-cell populations in mice. Apr 18, 2016

Pubmed Data : Int J Biol Macromol. 2016 Apr 19. Epub 2016 Apr 19. PMID: 27106589
Article Published Date : Apr 18, 2016
Study Type : Animal Study
Additional Links
Substances : Banana
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-17 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Upregulation
[+]

Oral administration of Lactobacillus plantarum 06CC2 prevents experimental colitis in mice via an anti‑inflammatory response.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2020 Mar ;21(3):1181-1191. Epub 2020 Jan 9. PMID: 31922249
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

P. incarnata treatment might be a potential therapy in the alcohol withdrawal syndrome.Jul 31, 2017

Pubmed Data : Phytother Res. 2017 Aug ;31(8):1199-1208. Epub 2017 Jun 1. PMID: 28568647
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Alcohol Withdrawal
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Interleukin-10 upregulation
Additional Keywords : Plant Extracts
[+]

Paeoniflorin can improve acute lung injury caused by severe acute pancreatitis through Nrf2/ARE pathway. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comput Math Methods Med. 2022 ;2022:5712219. Epub 2022 May 9. PMID: 35586665
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Lung Injury: Acute, Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis.Nov 30, 2013

Pubmed Data : Inflamm Res. 2013 Dec ;62(12):1035-44. Epub 2013 Oct 5. PMID: 24096935
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation
[+]

Paeoniflorin suppresses kidney inflammation by regulating macrophage polarization.Jul 24, 2023

Pubmed Data : Phytomedicine. 2023 Jul 25 ;116:154901. Epub 2023 May 24. PMID: 37247587
Article Published Date : Jul 24, 2023
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Chronic Kidney Disease (CKD), Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeonol accelerates skin wound healing by regulating macrophage polarization and inflammation in diabetic rats.Aug 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2023 Sep 1 ;27(5):437-448. PMID: 37641806
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Diabetic Ulcer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Panax notoginseng promotes repair of colonic microvascular injury in sprague-dawley rats with experimental colitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:4386571. Epub 2018 Jan 29. PMID: 29785192
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Panax notoginseng repairs vascular injury in experimental colitis.Dec 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2017 Dec 21 ;23(47):8308-8320. PMID: 29307991
Article Published Date : Dec 20, 2017
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Oxidative Stress, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Panax quinquefolius polysaccharides ameliorate ulcerative colitis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2023 ;14:1161625. Epub 2023 Jun 21. PMID: 37415978
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Ginseng (American)
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Passiflora edulis fruit peel extract could be used as an adjuvant for treating hypertension.Aug 02, 2021

Pubmed Data : Planta Med. 2021 Aug 3. Epub 2021 Aug 3. PMID: 34344056
Article Published Date : Aug 02, 2021
Study Type : Animal Study
Additional Links
Substances : Passion fruit
Diseases : Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation
[+]

Patchouli alcohol attenuates 5-fluorouracil-induced intestinal mucositis.Mar 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Apr ;124:109883. Epub 2020 Jan 28. PMID: 32004938
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil , Mucositis
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Microbiota
[+]

Peripheral activation of formyl peptide receptor 2/ALX by electroacupuncture alleviates inflammatory pain.Aug 09, 2023

Pubmed Data : Neuroscience. 2023 Aug 10 ;529:1-15. Epub 2023 Aug 10. PMID: 37572879
Article Published Date : Aug 09, 2023
Study Type : Animal Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Photobiomodulation may be considered a promising tool for the treatment of chronic pulmonary allergic inflammation observed in asthma.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Inflam. 2019 ;2019:3945496. Epub 2019 Mar 21. PMID: 31015955
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Asthma
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Physical exercise attenuates experimental autoimmune encephalomyelitis.Dec 31, 2016

Pubmed Data : Mol Neurobiol. 2017 08 ;54(6):4723-4737. Epub 2016 Jul 22. PMID: 27447807
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Encephalomyelitis, Multiple Sclerosis
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phytosterols ameliorate clinical manifestations and inflammation in experimental autoimmune encephalomyelitis.May 01, 2011

Pubmed Data : Inflamm Res. 2011 May;60(5):457-65. Epub 2010 Dec 7. PMID: 21136279
Article Published Date : May 01, 2011
Study Type : Animal Study
Additional Links
Substances : Phytosterols
Diseases : Multiple Sclerosis
Pharmacological Actions : Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Piperine improves experimental autoimmune encephalomyelitis.Aug 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Neurobiol. 2021 Aug 2. Epub 2021 Aug 2. PMID: 34338970
Article Published Date : Aug 01, 2021
Study Type : Animal Study
Additional Links
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Neuroprotective Agents, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Piperine treating sciatica through regulating inflammation and MiR-520a/P65 pathway.May 31, 2021

Pubmed Data : Chin J Nat Med. 2021 Jun ;19(6):412-421. PMID: 34092292
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Piperine
Diseases : Inflammation, Sciatica
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Polyphenol-rich extract of Ocimum gratissimum leaves ameliorates colitis.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:812-822. Epub 2018 Apr 24. PMID: 29684860
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : African Basil
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation
[+]

Polysaccharide from fermented mycelium of Inonotus obliquus attenuates the ulcerative colitis and adjusts the gut microbiota in mice.Mar 31, 2023

Pubmed Data : Microb Pathog. 2023 Apr ;177:105990. Epub 2023 Feb 3. PMID: 36739923
Article Published Date : Mar 31, 2023
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus), Fermented Foods and Beverages
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion.Feb 20, 2022

Pubmed Data : Food Funct. 2022 Feb 21 ;13(4):1941-1952. Epub 2022 Feb 21. PMID: 35088782
Article Published Date : Feb 20, 2022
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Cerebral Hypoperfusion, Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Neuroprotective Agents, Transforming growth factor beta (TGF-β) upregulation
Additional Keywords : Polysaccharides
[+]

Polysaccharide from Ganoderma lucidum ameliorates cognitive impairment.Aug 01, 2021

Pubmed Data : Food Funct. 2021 Aug 2 ;12(15):6900-6914. PMID: 34338268
Article Published Date : Aug 01, 2021
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Poricoic acid A inhibits the NF- κ B/MAPK pathway to alleviate renal fibrosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:8644353. Epub 2022 Jun 15. PMID: 35754696
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Poria cocos
Diseases : Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Renoprotective
[+]

Post-screening characterization of an acidic polysaccharide from Echinacea purpurea with potent anti-inflammatory properties in vivo.Sep 22, 2020

Pubmed Data : Food Funct. 2020 Sep 23 ;11(9):7576-7583. PMID: 32821898
Article Published Date : Sep 22, 2020
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Potential of myricetin to restore the immune balance in dextran sulfate sodium-induced acute murine ulcerative colitis.Nov 13, 2019

Pubmed Data : J Pharm Pharmacol. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31724745
Article Published Date : Nov 13, 2019
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Propolis may constitute a potential candidate to modulate inflammation during Celiac disease and has a potential therapeutic value.Mar 06, 2018

Pubmed Data : Inflammopharmacology. 2018 Mar 7. Epub 2018 Mar 7. PMID: 29516252
Article Published Date : Mar 06, 2018
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Celiac Disease
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Nitric Oxide Inhibitor
[+]

Protection against dextran sulfate sodium-induced ulcerative colitis in mice by neferine.Dec 31, 2020

Pubmed Data : Cell J. 2021 Jan ;22(4):523-531. Epub 2020 Apr 22. PMID: 32347046
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of dietary polysaccharides from yellow passion fruit peel on DSS-induced colitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:6298662. Epub 2022 Oct 15. PMID: 36285298
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Passion fruit
Diseases : Colitis, Inflammation, Inflammatory Bowel Diseases, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of procyanidin B2 on intestinal barrier and against enteritis in a mouse model of trinitrobenzene sulphonic acid-induced colitis.Jul 29, 2019

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2019 Jul 30 ;39(7):778-783. PMID: 31340909
Article Published Date : Jul 29, 2019
Study Type : Animal Study
Additional Links
Substances : Procyanidin B2
Diseases : Colitis, Crohn's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of Lycium ruthenicum Murr. juice on alcoholic liver injury in rats.Aug 31, 2022

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2022 Sep ;38(3):241-246. PMID: 36062793
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of naringenin and apigenin in ameliorating skin damage.May 23, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2023 May 24 ;12(11). Epub 2023 May 24. PMID: 37297362
Article Published Date : May 23, 2023
Study Type : Animal Study
Additional Links
Substances : Apigenin, Naringenin
Diseases : Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation
[+]

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway.Jun 09, 2021

Pubmed Data : Sci China Life Sci. 2021 Jun 10. Epub 2021 Jun 10. PMID: 34125371
Article Published Date : Jun 09, 2021
Study Type : Animal Study
Additional Links
Substances : Punicalagin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Resveratrol inhibits the inflammatory response and oxidative stress induced by uterine ischemia reperfusion injury.Dec 31, 2021

Pubmed Data : PLoS One. 2022 ;17(6):e0266961. Epub 2022 Jun 24. PMID: 35749345
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Ischemia, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Rosmarinic acid alleviates intestinal inflammatory damage.Aug 17, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiol Spectr. 2023 Aug 18:e0191423. Epub 2023 Aug 18. PMID: 37594285
Article Published Date : Aug 17, 2023
Study Type : Animal Study
Additional Links
Substances : Rosemaric Acid
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sage extract at low dose exhibits similar effects to rosiglitazone.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2018 ;6:e4166. Epub 2018 Jan 9. PMID: 29333341
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : High Fat Diet, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-2 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substances Versus Drugs
[+]

Sambucus nigra: A traditional medicine effective in reducing inflammation.Jan 29, 2022

Pubmed Data : J Ethnopharmacol. 2022 Jan 30 ;283:114736. Epub 2021 Oct 11. PMID: 34648899
Article Published Date : Jan 29, 2022
Study Type : Animal Study
Additional Links
Substances : Elderberry
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sesame oil therapy protects mice from developing experimental autoimmune encephalomyelitis by reducing IFN-gamma secretion.Apr 28, 2011

Pubmed Data : Phytother Res. 2011 Apr 28. Epub 2011 Apr 28. PMID: 21538630
Article Published Date : Apr 28, 2011
Study Type : Animal Study
Additional Links
Substances : Sesame Seed Oil
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation
[+]

Six types of tea could reduce acute alcoholism in this study.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:848918. Epub 2022 May 23. PMID: 35677547
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Alcoholism
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sulforaphane elicits antioxidant, anti-inflammatory, and extracellular matrix remodelling effects in a rat model of diabetic peripheral neuropathy.Aug 01, 2018

Pubmed Data : Inflammation. 2018 Aug ;41(4):1460-1476. PMID: 29704151
Article Published Date : Aug 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Malonaldehyde (MDA) Down-Regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Neuroprotective Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates
[+]

Systemic administration of Rosmarinus officinalis attenuates the inflammatory response induced by carrageenan in the mouse model of pleurisy.Oct 31, 2013

Pubmed Data : Planta Med. 2013 Nov ;79(17):1605-14. Epub 2013 Nov 28. PMID: 24288274
Article Published Date : Oct 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosemary
Diseases : Asthma, Inflammation, Pleurisy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Tanshinone IIA ameliorate coxsackie virus B3-induced viral myocarditis. Dec 31, 2018

Pubmed Data : Pharmacology. 2019 ;103(3-4):136-142. Epub 2019 Jan 2. PMID: 30602153
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Coxsackievirus Infections, Myocarditis: Viral
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation
[+]

Tanshinone IIA attenuates diabetic peripheral neuropathic pain.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:2789847. Epub 2018 Mar 11. PMID: 29713362
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA exerts immune modulatory effect and might be a useful strategy to ameliorate immunosuppression in polymicrobial sepsis.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Apr ;112:108609. Epub 2019 Feb 20. PMID: 30784917
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Peritonitis, Sepsis
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation
[+]

Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response.Jul 31, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 Aug 1. Epub 2018 Aug 1. PMID: 30078676
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Multiple Sclerosis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-18 down-regulation
[+]

Tetramethylpyrazine attenuates experimental autoimmune myasthenia gravis.Oct 31, 2016

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016 Nov ;32(11):1471-1474. PMID: 27774937
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Myasthenia Gravis
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The antimalarial effect of curcumin is mediated by the inhibition of glycogen synthase kinase-3β.Jan 31, 2017

Pubmed Data : J Med Food. 2017 Feb ;20(2):152-161. PMID: 28146408
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Malaria
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The effects of acetyl-11-keto-β-boswellic acid on brain cytokines and memory impairment induced by lipopolysaccharide. Jun 30, 2020

Pubmed Data : Cytokine. 2020 Jul ;131:155107. Epub 2020 May 4. PMID: 32380425
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The gastroprotective effect of small molecule oligopeptides isolated from walnut against ethanol-induced gastric mucosal injury.Apr 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 18 ;12(4). Epub 2020 Apr 18. PMID: 32325708
Article Published Date : Apr 17, 2020
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Alcohol Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The hydroalcoholic extract of saffron can be considered as a useful strategy in the treatment of type 1 diabetes.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Allergy Asthma Immunol. 2019 Feb ;18(1):38-47. PMID: 30848572
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

The present research broadens the therapeutic scope of Quercetin in central nervous system (CNS) disorders.Mar 09, 2022

Pubmed Data : Mol Neurobiol. 2022 Mar 10. Epub 2022 Mar 10. PMID: 35267135
Article Published Date : Mar 09, 2022
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Neuroprotective Agents
[+]

The protective effect and mechanism of lentinan on acute kidney injury in septic rats.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2020 Jul ;8(14):883. PMID: 32793727
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Shitake Mushroom
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The protective role of garlic on allergen-induced airway inflammation.Dec 31, 2018

Pubmed Data : Am J Chin Med. 2019 ;47(5):1099-1112. Epub 2019 Jul 31. PMID: 31366207
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-12 upregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Therapeutic effects of standardized Vitex negundo seeds extract on complete Freund's adjuvant induced arthritis.May 14, 2014

Pubmed Data : Phytomedicine. 2014 May 15 ;21(6):838-46. Epub 2014 Mar 25. PMID: 24680620
Article Published Date : May 14, 2014
Study Type : Animal Study
Additional Links
Substances : Lignans, Vitex negundo
Diseases : Arthritis, Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Therapeutic ultrasound in combination with treadmill training reduces neuropathic pain more than either modality alone.Apr 27, 2016

Pubmed Data : Phys Ther. 2016 Apr 28. Epub 2016 Apr 28. PMID: 27126126
Article Published Date : Apr 27, 2016
Study Type : Animal Study
Additional Links
Diseases : Peripheral Neuropathies
Therapeutic Actions : Exercise, Ultrasound
Pharmacological Actions : Analgesics, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

These findings show that physical exercise modulates pulmonary allergic inflammation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:854. Epub 2019 May 16. PMID: 31156611
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Asthma
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

These findings suggest that blackberry consumption could help prevent or reduce manic episodes.Dec 31, 2019

Pubmed Data : Neurosci Lett. 2020 Jan 1 ;714:134566. Epub 2019 Nov 4. PMID: 31698027
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Blackberry
Diseases : Mania: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

These findings suggested that buckwheat and bee pollen extract had the effects of alleviating colitis and immunomodulation.Apr 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Apr 29 ;11(9). Epub 2022 Apr 29. PMID: 35564016
Article Published Date : Apr 28, 2022
Study Type : Animal Study
Additional Links
Substances : Bee Pollen, Buckwheat
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results provide insights into butyrate as a potential therapeutic for the treatment of inflammatory bowel disease.Mar 26, 2019

Pubmed Data : Inflamm Bowel Dis. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30918945
Article Published Date : Mar 26, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Butyrate
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation
[+]

These results recognize the high anti-inflammatory and immunomodulatory potential of the L. bulgaricus 151 and S. thermophiles.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dairy Sci. 2019 Jan ;102(1):37-53. Epub 2018 Oct 19. PMID: 30343915
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Streptococcus thermophilus, Yoghurt
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-2 upregulation, Interleukin-4 upregulation
[+]

These results suggest that 6-gingerol suppresses inflammation.Aug 14, 2016

Pubmed Data : Planta Med. 2016 Aug 15. Epub 2016 Aug 15. PMID: 27525509
Article Published Date : Aug 14, 2016
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

These results suggest that L. paracasei KW3110 may have a preventive effect against degrative retinal diseases.Dec 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 15 ;10(12). Epub 2018 Dec 15. PMID: 30558320
Article Published Date : Dec 14, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Blue Light Toxicity, Inflammation, Macular Degeneration, Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

This suggested that polyphenol-rich by-products might provide a similar health effect in high-fat diet individuals.Mar 31, 2020

Pubmed Data : Food Funct. 2020 Apr 1 ;11(4):3167-3179. Epub 2020 Mar 24. PMID: 32208477
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Blueberry, Fermented Foods and Beverages, Polyphenols
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone may be an important agent for the treatment of sepsis-induced liver injury.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Sep ;18(3):1985-1992. Epub 2019 Jul 17. PMID: 31410159
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Liver Damage, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ursolic acid enhances myelin repair in adult mice brains.Aug 16, 2022

Pubmed Data : J Mol Neurosci. 2022 Aug 17. Epub 2022 Aug 17. PMID: 35976486
Article Published Date : Aug 16, 2022
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Remyelination
[+]

Vitamin D has an effect on airway inflammation and Th17/Treg balance in asthmatic mice.Aug 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2021 Aug 30. Epub 2021 Aug 30. PMID: 34460994
Article Published Date : Aug 29, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Vitamin K2 alleviated the DSS-induced colitis.Feb 02, 2023

Pubmed Data : Int J Mol Sci. 2023 Feb 3 ;24(3). Epub 2023 Feb 3. PMID: 36769323
Article Published Date : Feb 02, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke.Feb 28, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar ;99:583-590. Epub 2018 Feb 20. PMID: 29710456
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Autophagy Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Yarrow oil ameliorates ulcerative colitis in mice.Aug 20, 2020

Pubmed Data : Intest Res. 2020 Aug 21. Epub 2020 Aug 21. PMID: 32819032
Article Published Date : Aug 20, 2020
Study Type : Animal Study
Additional Links
Substances : Yarrow
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Zataria multiflora essential oil accelerated the healing process of infected wounds.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2021 Dec ;59(1):1-10. PMID: 33378625
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Substances : Zataria multiflora
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus plantarum OLL2712 induces IL-10 production by intestinal dendritic cells. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Microbiota Food Health. 2020 ;39(2):39-44. Epub 2019 Nov 29. PMID: 32328399
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Inflammation
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation
[+]

A fucoidan-gelatin wound dressing accelerates wound healing.Nov 02, 2022

Pubmed Data : Int J Biol Macromol. 2022 Nov 3 ;223(Pt A):36-48. Epub 2022 Nov 3. PMID: 36336154
Article Published Date : Nov 02, 2022
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Wound Healing
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A trypsin inhibitor from Moringa oleifera flowers modulates the immune response in vitro of Trypanosoma cruzi-infected human cells.Aug 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2020 Aug 14 ;9(8). Epub 2020 Aug 14. PMID: 32823803
Article Published Date : Aug 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera
Diseases : Chagas Disease, Parasitic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antiparasitic Agents, Interleukin-10 upregulation
[+]

A. princeps may be useful in the treatment of autoimmune diseases and organ transplantation rejection. Jul 31, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Aug ;61(8):1043-50. PMID: 19703348
Article Published Date : Jul 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Japanese mugwort
Diseases : Autoimmune Diseases, Organ Transplantation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
Additional Keywords : Plant Extracts
[+]

Adaptive immunoregulation of luteolin and chlorogenic acid in lipopolysaccharide-induced interleukin-10 expression.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ci Ji Yi Xue Za Zhi. 2019 Apr-Jun;32(2):186-192. Epub 2019 Jun 24. PMID: 32269953
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Luteolin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

Adhesion-related immunomodulatory activity of the screened Lactobacillus plantarum from sichuan pickle.Dec 31, 2018

Pubmed Data : Curr Microbiol. 2019 Jan ;76(1):29-36. Epub 2018 Oct 9. PMID: 30302554
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-8 downregulation
[+]

Alantolactone enhances the phagocytic properties of human macrophages and modulates their proinflammatory functions.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1339. Epub 2020 Sep 3. PMID: 33013371
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory activity of polysaccharides from Phellinus linteus.May 14, 2019

Pubmed Data : Int J Biol Macromol. 2019 May 15 ;129:61-67. Epub 2019 Feb 4. PMID: 30731160
Article Published Date : May 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Phellinus Linteus
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Anti-inflammatory effect of vanillin protects the stomach against ulcer formation.Mar 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Mar 30 ;14(4). Epub 2022 Mar 30. PMID: 35456589
Article Published Date : Mar 29, 2022
Study Type : In Vitro Study
Additional Links
Substances : Vanillin
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory properties of honokiol in activated primary microglia and astrocytes.Oct 14, 2018

Pubmed Data : J Neuroimmunol. 2018 Oct 15 ;323:78-86. Epub 2018 Jul 25. PMID: 30196838
Article Published Date : Oct 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-neuroinflammatory of chloroform extract of Panax ginseng root culture on lipopolysaccharide-stimulated BV2 microglia cells.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rep Biochem Mol Biol. 2022 Apr ;11(1):125-137. PMID: 35765526
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Ginseng
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antihypertensive effect of carvacrol is improved after incorporation in β-cyclodextrin as a drug delivery system.Oct 31, 2020

Pubmed Data : Clin Exp Pharmacol Physiol. 2020 Nov ;47(11):1798-1807. Epub 2020 Aug 7. PMID: 32568422
Article Published Date : Oct 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation
[+]

Apigenin, resveratrol and kaempferol may reduce the intensity of inflammatory processes.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:1205-1212. Epub 2017 Jul 20. PMID: 28738536
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Kaempferol, Resveratrol
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV protects neurons from microglia-mediated cell damage through promoting microglia polarization.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Neuropathol. 2019 ;57(2):170-181. PMID: 31556576
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein alleviated the brain injury after Intracerebral hemorrhage by inhibiting ROS and NLRP3 inflammasome.Oct 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Inflammation. 2021 Oct 8. Epub 2021 Oct 8. PMID: 34625906
Article Published Date : Oct 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Intracerebral Hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Biomedical properties of propolis on diverse chronic diseases.Dec 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Dec 29 ;13(1). Epub 2020 Dec 29. PMID: 33383693
Article Published Date : Dec 28, 2020
Study Type : Review
Additional Links
Substances : Propolis: Bee
Diseases : Cancers: All, Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

C-Phycocyanin and Lycium barbarum polysaccharides protect against aspirin-induced Inflammation and apoptosis.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Dec 1 ;14(23). Epub 2022 Dec 1. PMID: 36501143
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Goji
Diseases : Aspirin-Induced Toxicity , Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Gastroprotective, Interleukin-10 upregulation
Additional Keywords : Polysaccharides
Problem Substances : Aspirin
[+]

Carnosol suppresses microglia cell inflammation and apoptosis through PI3K/AKT/mTOR signaling pathway.May 05, 2022

Pubmed Data : Immunopharmacol Immunotoxicol. 2022 May 6:1-11. Epub 2022 May 6. PMID: 35521965
Article Published Date : May 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Inflammation, Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carvacrol exhibits modulatory effects on expression of pro-and anti-inflammatory cytokines.Feb 14, 2019

Pubmed Data : Life Sci. 2019 Feb 15 ;219:257-263. Epub 2018 Nov 23. PMID: 30472298
Article Published Date : Feb 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Chrysin attenuates global cerebral ischemic reperfusion injury via suppression of oxidative stress, inflammation and apoptosis.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Apr ;112:108619. Epub 2019 Feb 20. PMID: 30797156
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Brain Ischemia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Citric acid treatment enhanced the anti-inflammatory activity of wheat germ extract.Jul 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Jul 10 ;9(7). Epub 2017 Jul 10. PMID: 28698513
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citric Acid , Fermented Foods and Beverages, Wheat Germ
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:963662. Epub 2022 Sep 8. PMID: 36159482
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Orange
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cucumis sativus L. extract attenuated lipopolysaccharide-induced inflammatory response in endothelial cells.Jun 24, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Jun 25 ;18(1):194. Epub 2018 Jun 25. PMID: 29941006
Article Published Date : Jun 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cucumber
Diseases : Alcohol Toxicity , Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-18 upregulation, Interleukin-1 alpha downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
Additional Keywords : Plant Extracts
[+]

Curcuma aromatica protects from acetaminophen-induced hepatotoxicity.Feb 03, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Feb 4 ;15(4). Epub 2023 Feb 4. PMID: 36839166
Article Published Date : Feb 03, 2023
Study Type : In Vitro Study
Additional Links
Substances : Turmeric
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acetaminophen, Paracetamol
[+]

Curcumin attenuates beta-amyloid-induced toxicity through beta-catenin and PI3K signalling.Sep 30, 2013

Pubmed Data : Neurol Res. 2013 Oct ;35(8):857-66. Epub 2013 May 14. PMID: 23816368
Article Published Date : Sep 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Diospyros malabarica fruits extract attenuated acute and chronic inflammation.Nov 30, 2022

Pubmed Data : Inflammopharmacology. 2022 Dec ;30(6):2211-2227. Epub 2022 Oct 12. PMID: 36223063
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Persimmon
Diseases : Arthritis, Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Electroacupuncture treatment could be partially associated with suppression of pro-inflammatory cytokines mediated by induction of IL-10.Mar 19, 2020

Pubmed Data : Inflammation. 2020 Mar 20. Epub 2020 Mar 20. PMID: 32198725
Article Published Date : Mar 19, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Galangin as an inflammatory response modulator: An updated overview and therapeutic potential.May 31, 2023

Pubmed Data : Chem Biol Interact. 2023 Jun 1 ;378:110482. Epub 2023 Apr 10. PMID: 37044286
Article Published Date : May 31, 2023
Study Type : Review
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genomic diversity and immunomodulatory activity of Lactobacillus plantarum isolated from dairy products.Aug 23, 2017

Pubmed Data : Benef Microbes. 2017 Aug 24 ;8(4):597-604. Epub 2017 May 30. PMID: 28555501
Article Published Date : Aug 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Inflammation
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation, Interleukin-12 downregulation
[+]

Ginsenoside Rd may be a potential immunomodulating agent or supplement that can be applied for transplantation and autoimmune disorders.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Biotechnol. 2018 Feb ;27(1):227-232. Epub 2017 Nov 23. PMID: 30263744
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ginseng (Korean), Ginsenosides
Diseases : Autoimmune Diseases
Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation
[+]

Ginsenoside Rg3 alleviates inflammation in a rat model of myocardial infarction via the SIRT1/NF-κB pathway.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Dec ;20(6):238. Epub 2020 Oct 22. PMID: 33193843
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Glycyrrhizin micellar nanocarriers for topical delivery of baicalin to the hair follicles: A targeted approach tailored for alopecia treatment.Sep 24, 2022

Pubmed Data : Int J Pharm. 2022 Sep 25 ;625:122109. Epub 2022 Aug 13. PMID: 35973589
Article Published Date : Sep 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Glycyrrhizin
Diseases : Alopecia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Gypenoside attenuates β amyloid-induced inflammation in N9 microglial cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2016 ;2016:6362707. Epub 2016 Apr 26. PMID: 27213058
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Gynostemma
Diseases : Brain Inflammation
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Hemp protein hydrolysates promote anti-inflammatory response in primary human monocytes.May 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 May 22 ;10(5). Epub 2020 May 22. PMID: 32456009
Article Published Date : May 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Hemp Seed
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Immunomodulatory effects of Lactobacillus plantarum on inflammatory response induced by Klebsiella pneumoniae.Sep 02, 2019

Pubmed Data : Infect Immun. 2019 Sep 3. Epub 2019 Sep 3. PMID: 31481408
Article Published Date : Sep 02, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Klebsiella Infections
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

In vitro adhesion and anti-inflammatory properties of native Lactobacillus fermentum and Lactobacillus delbrueckii spp.Mar 13, 2018

Pubmed Data : J Appl Microbiol. 2018 Mar 14. Epub 2018 Mar 14. PMID: 29537703
Article Published Date : Mar 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus delbrueckii Subsp, Lactobacillus fermentum
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Kaempferol may serve as a novel target for treatment of Intervertebral disc degeneration.Dec 29, 2016

Pubmed Data : Int Immunopharmacol. 2016 Dec 30 ;43:236-242. Epub 2016 Dec 30. PMID: 28043032
Article Published Date : Dec 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Degenerative Disk Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

L. helveticus NS8 exhibited good probiotic and particularly immunomodulatory properties.Oct 01, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Microbiol. 2015 Oct 2 ;15:196. Epub 2015 Oct 2. PMID: 26428623
Article Published Date : Oct 01, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus helveticus
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Lactobacillus paracasei KW3110 prevents inflammatory-stress-induced mitochondrial dysfunction.Jan 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Jan 27 ;23(3). Epub 2022 Jan 27. PMID: 35163375
Article Published Date : Jan 26, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Lactobacillus plantarum HNU082 alleviates dextran sulfate sodium-induced ulcerative colitis.Oct 02, 2022

Pubmed Data : Food Funct. 2022 Oct 3 ;13(19):10171-10185. Epub 2022 Oct 3. PMID: 36111438
Article Published Date : Oct 02, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

M. citrifolia leaf extract suppressed inflammation, and potential metastasis by inhibiting new cancer-related blood vessel formation.Jun 30, 2019

Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12868. Epub 2019 Apr 24. PMID: 31353737
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Leukemia
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Apoptotic, Interleukin-10 upregulation, Interleukin-4 upregulation

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