Interleukin-17 downregulation

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72 Substances Researched for Interleukin-17 downregulation
NameACCKFocus
Curcumin314Locked
Alpha-Lipoic Acid212Locked
Oleuropein212Locked
Paeoniflorin711Locked
Crocin110Locked
Ligustrazine36Locked
Probiotics35Locked
Berberine24Locked
Hyperforin24Locked
Lactobacillus casei24Locked
Peony24Locked
Cannabidiol23Locked
Vitamin E23Locked
Achiote12Locked
Anthocyanins12Locked
Artesunate12Locked
Astragaloside12Locked
Astragalus12Locked
Barley12Locked
Beta-Caryophyllene12Locked
Black Raspberry12Locked
Bromelain12Locked
Carnosic Acid12Locked
Carnosine12Locked
Carvacrol12Locked
EGCG (Epigallocatechin gallate)12Locked
Evening Primrose Oil12Locked
Fermented Foods and Beverages12Locked
Ferulic acid12Locked
Flavonoids12Locked
Ginseng (Korean)12Locked
Ginsenosides12Locked
Glycyrrhizin12Locked
Gotu Kola12Locked
Grape12Locked
Hemp Seed12Locked
Lactobacillus fermentum12Locked
Lactobacillus rhamnosus 12Locked
Lactobacillus salivarius 12Locked
Lavender: Essential Oil12Locked
Mangosteen12Locked
Noni12Locked
Okra12Locked
Oridonin12Locked
Parthenolide12Locked
Patchouli12Locked
Perillaldehyde12Locked
Phloretin12Locked
Pomegranate12Locked
Propolis: Bee12Locked
Quercetin12Locked
Raspberry12Locked
Saffron12Locked
Selenium12Locked
Shikonin22Locked
St. Johns Wort12Locked
Sulforaphane12Locked
Sweet Potato: Purple12Locked
Tarragon12Locked
Tetrahydrocurcumin12Locked
Vanillin12Locked
Vitamin D12Locked
Zinc12Locked
Almond11Locked
Cannabinoids 11Locked
Capparis spinosa (caper)11Locked
Cucurbitacin E 11Locked
Green Tea11Locked
Lactobacillus plantarum11Locked
Lupine11Locked
Resveratrol11Locked
Vitexins11Locked

View the Evidence:
89 Abstracts with Interleukin-17 downregulation Research

[+]

Electroacupuncture could effectively reduce the suffering and improve the quality of life of rheumatoid arthritis patients.Jul 31, 2019

Pubmed Data : J Tradit Chin Med. 2019 Aug ;39(4):582-586. PMID: 32186107
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Lipoic acid down-regulates inflammation in multiple sclerosis patients.Jan 01, 2010

Pubmed Data : PLoS One. 2010;5(9). Epub 2010 Sep 28. PMID: 20927401
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : cAMP up-regulation, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

These new data support a potential role of oleuropein in the treatment of ulcerative colitis.Apr 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Apr 15 ;9(4). Epub 2017 Apr 15. PMID: 28420140
Article Published Date : Apr 14, 2017
Study Type : Human Study
Additional Links
Substances : Oleuropein
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation
[+]

These results suggest the beneficial and therapeutic effects of crocin in multiple sclerosis.Oct 15, 2019

Pubmed Data : J Biochem Mol Toxicol. 2019 Oct 16:e22410. Epub 2019 Oct 16. PMID: 31617649
Article Published Date : Oct 15, 2019
Study Type : Human Study
Additional Links
Substances : Crocin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Transmucosal administration of microgranular curcumin leads to enhanced curcumin bioavailability.Nov 30, 2015

Pubmed Data : Anticancer Res. 2015 Dec ;35(12):6411-8. PMID: 26637850
Article Published Date : Nov 30, 2015
Study Type : Human Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Interleukin-17 downregulation
Additional Keywords : Increased Bioavailability
[+]

Lactobacillus casei could act as a potent nutraceutical modulator forosteoarthritis treatment by reducing pain, inflammatory responses, and articular cartilage degradation.Dec 16, 2010

Pubmed Data : Life Sci. 2010 Dec 16. Epub 2010 Dec 16. PMID: 21167838
Article Published Date : Dec 16, 2010
Study Type : Animal Study
Additional Links
Substances : Lactobacillus casei
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-17 downregulation, Interleukin-2 Downregulation, Matrix Metalloproteinases Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.May 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 May 11 ;25(9). Epub 2020 May 11. PMID: 32403241
Article Published Date : May 10, 2020
Study Type : Animal Study
Additional Links
Substances : Grape, Pomegranate, Propolis: Bee
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation
[+]

Administering curcumin may alleviate cerebral inflammation resulting from intracerebral hemorrhage.Mar 25, 2016

Pubmed Data : Neurosci Lett. 2016 Mar 26 ;620:74-82. Epub 2016 Mar 26. PMID: 27026486
Article Published Date : Mar 25, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation
[+]

Administration of Epigallocatechin-3-gallate resulted in a significant reduction in bone loss.Sep 06, 2015

Pubmed Data : Int Immunopharmacol. 2015 Sep 7. Epub 2015 Sep 7. PMID: 26359545
Article Published Date : Sep 06, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Gingivitis, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-psoriatic effect of Lavandula angustifolia essential oil and its major components linalool and linalyl acetate.Jul 01, 2020

Pubmed Data : J Ethnopharmacol. 2020 Jul 2:113127. Epub 2020 Jul 2. PMID: 32623016
Article Published Date : Jul 01, 2020
Study Type : Animal Study
Additional Links
Substances : Lavender: Essential Oil
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, NF-kappaB Inhibitor
[+]

Artemisia dracunculus L. modulates the immune system in a multiple sclerosis mouse model.Oct 30, 2019

Pubmed Data : Nutr Neurosci. 2019 Oct 31:1-7. Epub 2019 Oct 31. PMID: 31665978
Article Published Date : Oct 30, 2019
Study Type : Animal Study
Additional Links
Substances : Tarragon
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2016 Mar ;32:32-38. Epub 2016 Jan 16. PMID: 26784569
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV stimulates hippocampal neurogenesis after stroke.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:421. Epub 2020 Apr 3. PMID: 32317974
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Stroke
Pharmacological Actions : Interleukin-17 downregulation, Neurogenesis
[+]

Berberine attenuates arthritis in adjuvant-induced arthritis.Feb 19, 2019

Pubmed Data : Eur J Pharmacol. 2019 Feb 20. Epub 2019 Feb 20. PMID: 30796904
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation, NF-kappaB Inhibitor
[+]

Berberine exerted a superior anti-arthritic effect and the mechanism maybe involve the balance between Treg and Th17 cells.Mar 05, 2017

Pubmed Data : Biomed Pharmacother. 2017 Mar 6 ;89:887-893. Epub 2017 Mar 6. PMID: 28282791
Article Published Date : Mar 05, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

Beta-Caryophyllene ameliorates the development of experimental autoimmune encephalomyelitis.Apr 28, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr 29 ;91:257-264. Epub 2017 Apr 29. PMID: 28463791
Article Published Date : Apr 28, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Autoimmune Diseases, Encephalomyelitis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bixin attenuates experimental autoimmune encephalomyelitis. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2020 ;11:593368. Epub 2020 Dec 9. PMID: 33362775
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Bixin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Black raspberries and protocatechuic acid mitigate DNFB-induced contact hypersensitivity.Jun 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jun 6 ;12(6). Epub 2020 Jun 6. PMID: 32517233
Article Published Date : Jun 05, 2020
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Hypersensitivity
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-12 downregulation, Interleukin-17 downregulation
[+]

Bromelain has a therapeutic effect in established allergic airway disease.Aug 31, 2012

Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):9-17. PMID: 22894886
Article Published Date : Aug 31, 2012
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Allergic Airway Diseases, Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-12 downregulation, Interleukin-17 downregulation, Interleukin-4 downregulation
[+]

Cannabidiol was found to promote neuronal survival by inhibiting JNK and p38 MAP kinases.Nov 24, 2016

Pubmed Data : Fitoterapia. 2016 Nov 25 ;116:77-84. Epub 2016 Nov 25. PMID: 27890794
Article Published Date : Nov 24, 2016
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Neuroprotective Agents
[+]

Curcumin ameloriates experimental autoimmune encephalomyelitis through inhibition of IL-17 production.May 01, 2009

Pubmed Data : Int Immunopharmacol. 2009 May;9(5):575-81. Epub 2009 Feb 3. PMID: 19539560
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Multiple Sclerosis
Pharmacological Actions : Antiproliferative , Interleukin-17 downregulation, Interleukin-21 downregulation, Interleukin-6 Downregulation
[+]

Dietary red raspberries attenuate dextran sulfate sodium-induced acute colitis.Dec 31, 2017

Pubmed Data : J Nutr Biochem. 2018 01 ;51:40-46. Epub 2017 Sep 14. PMID: 29091813
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Raspberry
Diseases : Colitis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary selenium supplementation alleviates immune toxicity in the hearts of chickens with lead-added drinking water.May 31, 2019

Pubmed Data : Avian Pathol. 2019 Jun ;48(3):230-237. Epub 2019 Feb 18. PMID: 30663336
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Lead Poisoning
Pharmacological Actions : Cardioprotective, Immunomodulatory, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-2 Downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation
Problem Substances : Lead
[+]

Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease.Dec 31, 2019

Pubmed Data : Vopr Pitan. 2020;89(5):6-16. Epub 2020 Sep 20. PMID: 33211913
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Carnosine
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-1 alpha downregulation
[+]

Enteral exposure to P histicola suppresses arthritis via mucosal regulation.Jan 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Rheumatol. 2016 12 ;68(12):2878-2888. PMID: 27337150
Article Published Date : Jan 11, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Probiotics
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

Fermented barley extract alleviates atopic dermatitis like skin lesions in NC/Nga mice.Mar 22, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2009 Mar 23 ;73(3):489-93. Epub 2009 Mar 7. PMID: 19270394
Article Published Date : Mar 22, 2009
Study Type : Animal Study
Additional Links
Substances : Barley, Fermented Foods and Beverages
Diseases : Atopic Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation
Additional Keywords : Plant Extracts
[+]

Fermented milk appears to potentially play a role in decreasing the Th17 response.Aug 07, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Aug 8 ;10(8). Epub 2018 Aug 8. PMID: 30096797
Article Published Date : Aug 07, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Ferulic acid altered IL-17A/IL-17RA interaction and protected against imiquimod-induced psoriasis-like skin injuryJun 30, 2019

Pubmed Data : Food Chem Toxicol. 2019 Jul ;129:365-375. Epub 2019 May 3. PMID: 31054998
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Psoriasis
Pharmacological Actions : Interleukin-17 downregulation
Additional Keywords : Gene Expression Regulation
[+]

Ginsenoside F2 may be a novel therapeutic approach for treating skin inflammation.Sep 29, 2016

Pubmed Data : Biochem Biophys Res Commun. 2016 Sep 30 ;478(4):1713-9. Epub 2016 Sep 3. PMID: 27596969
Article Published Date : Sep 29, 2016
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-17 downregulation
[+]

Glycyrrhizin alleviates Con A-induced hepatitis.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Feb ;110:692-699. Epub 2018 Dec 12. PMID: 30553196
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Glycyrrhizin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation
Problem Substances : Concanavalin A
[+]

Glycyrrhizin improves the pathogenesis of psoriasis.May 26, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Immunol. 2021 May 27 ;22(1):34. Epub 2021 May 27. PMID: 34044769
Article Published Date : May 26, 2021
Study Type : Animal Study
Additional Links
Substances : Glycyrrhizin
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation
[+]

Hemp seed and evening primrose oils treatment can be used to ameliorate the demyelination of spinal cord.Mar 31, 2019

Pubmed Data : Res Pharm Sci. 2019 Apr ;14(2):146-154. Epub 2019 Mar 8. PMID: 31620191
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil, Hemp Seed
Diseases : Encephalomyelitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, STAT3 Inhibitor
[+]

Hyperforin could promote functional recovery when delivered in the later phases of stroke recovery.Aug 31, 2016

Pubmed Data : Brain Res. 2016 Sep 1 ;1646:504-13. Epub 2016 Jun 17. PMID: 27328426
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Hyperforin, St. Johns Wort
Diseases : Stroke: Attenuation/Recovery
Pharmacological Actions : Interleukin-17 downregulation, Neuroprotective Agents
[+]

Hyperforin could protect against acute cerebral ischemic injury.Dec 31, 2017

Pubmed Data : Brain Res. 2018 Jan 1 ;1678:254-261. Epub 2017 Sep 1. PMID: 28870826
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hyperforin
Diseases : Cerebral Ischemia
Pharmacological Actions : Interleukin-17 downregulation, Neuroprotective Agents
[+]

Inhibitory effect of Centella asiatica extract on DNCB-induced atopic dermatitis.Feb 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Feb 5 ;12(2). Epub 2020 Feb 5. PMID: 32033291
Article Published Date : Feb 04, 2020
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 downregulation, Interleukin-17 downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

KGC3P attenuates ovalbumin-induced airway inflammation through downregulation of p-PTEN in asthmatic mice.Apr 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2019 Apr 30 ;62:152942. Epub 2019 Apr 30. PMID: 31102886
Article Published Date : Apr 29, 2019
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-17 downregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus salivarius LA307 and Lactobacillus rhamnosus LA305 attenuate skin inflammation.Feb 26, 2018

Pubmed Data : Benef Microbes. 2018 Feb 27 ;9(2):299-309. Epub 2018 Feb 7. PMID: 29409331
Article Published Date : Feb 26, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus , Lactobacillus salivarius
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-22 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ligustrazine could alleviate the airway inflflammation in the neutrophilic asthma mice model.Apr 30, 2018

Pubmed Data : Chin J Integr Med. 2018 May ;24(5):353-358. Epub 2017 Oct 30. PMID: 29086220
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):455-464. PMID: 31070537
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation, Interleukin-17 downregulation
Additional Keywords : Natural Substance/Drug Synergy
[+]

Okra polysaccharides could act as an effective material to enhance immune response.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Sci. 2018 ;2018:8505383. Epub 2018 Oct 9. PMID: 30402093
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Immunostimulatory, Interleukin-17 downregulation
Additional Keywords : Polysaccharides
[+]

Oleuropein supplementation could be a promising protective agent against colitis-associated colorectal cancer.Sep 28, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Sep 29. Epub 2015 Sep 29. PMID: 26502315
Article Published Date : Sep 28, 2015
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Colitis, Colorectal Cancer: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Wnt/β-catenin pathway down-regulation
[+]

Oral administration of paeoniflorin attenuates allergic contact dermatitis.Mar 31, 2015

Pubmed Data : Int Immunopharmacol. 2015 Apr ;25(2):432-9. Epub 2015 Mar 3. PMID: 25744601
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dermatitis
Pharmacological Actions : Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-17 downregulation
[+]

Oridonin ameliorates experimental autoimmune encephalomyelitis.May 31, 2020

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2020 Jun ;36(6):492-498. PMID: 32696738
Article Published Date : May 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Encephalomyelitis
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-17 downregulation
[+]

Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1 ;306(1):G27-36. Epub 2013 Nov 14. PMID: 24232001
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin ameliorates experimental autoimmune encephalomyelitis.Jan 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 02 6 ;7:41887. Epub 2017 Feb 6. PMID: 28165507
Article Published Date : Jan 05, 2017
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Multiple Sclerosis
Pharmacological Actions : Interleukin-17 downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis.Nov 30, 2013

Pubmed Data : Inflamm Res. 2013 Dec ;62(12):1035-44. Epub 2013 Oct 5. PMID: 24096935
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation
[+]

Parthenolide modulates immune response in cells from C57BL/6 mice induced with experimental autoimmune encephalomyelitis.Apr 30, 2017

Pubmed Data : Planta Med. 2017 May ;83(8):693-700. Epub 2016 Dec 20. PMID: 27997959
Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Parthenolide
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Patchouli alcohol: a natural sesquiterpene against both inflammation and intestinal barrier damage of ulcerative colitis. Jul 31, 2020

Pubmed Data : Inflammation. 2020 Aug ;43(4):1423-1435. PMID: 32388657
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Perillaldehyde has a significant preventative and therapeutic effect on vaginal candidiasis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2019 ;10:1466. Epub 2019 Jul 2. PMID: 31333606
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perillaldehyde
Diseases : Candidiasis: Vulvovaginal
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-22 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phloretin could be a potent and effective antiarthritis agent.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:9831263. Epub 2016 Dec 4. PMID: 28044086
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Purple-fleshed potato has the potential to aid in the amelioration of ulcerative colitis symptoms.Mar 07, 2021

Pubmed Data : J Nutr Biochem. 2021 Mar 8:108616. Epub 2021 Mar 8. PMID: 33705951
Article Published Date : Mar 07, 2021
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Sweet Potato: Purple
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Quercetin may be an alternative treatment for rheumatoid arthritis because it modulates the main pathogenic pathways.Mar 21, 2017

Pubmed Data : Biomed Pharmacother. 2017 Mar 22 ;90:38-46. Epub 2017 Mar 22. PMID: 28342364
Article Published Date : Mar 21, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Rosemary derived carnosic acid is a promising natural compound for the treatment of rheumatoid arthritis.Jul 31, 2018

Pubmed Data : J Cell Physiol. 2018 Aug ;233(8):6291-6303. Epub 2018 Mar 9. PMID: 29521424
Article Published Date : Jul 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Arthritis, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid protects mice from imiquimod induced psoriasis-like skin lesions.May 17, 2021

Pubmed Data : Phytother Res. 2021 May 18. Epub 2021 May 18. PMID: 34008239
Article Published Date : May 17, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

Study on the physicochemical properties and anti-inflammatory effects of paeonol in rats with TNBS-induced ulcerative colitis.Dec 31, 2016

Pubmed Data : Int Immunopharmacol. 2017 Jan ;42:32-38. Epub 2016 Nov 15. PMID: 27863299
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

Sulforaphane may have therapeutic value in the treatment of rheumatoid arthritis.Jan 01, 2010

Pubmed Data : Arthritis Rheum. 2010 Jan;62(1):159-70. PMID: 20039434
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Supplementation with tetrahydrocurcumin enhances the therapeutic effects of dexamethasone in a murine model of allergic asthma.Dec 31, 2019

Pubmed Data : Int Arch Allergy Immunol. 2020 ;181(11):822-830. Epub 2020 Aug 12. PMID: 32784298
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
Additional Keywords : Natural Substance Synergy
[+]

Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response.Jul 31, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 Aug 1. Epub 2018 Aug 1. PMID: 30078676
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Multiple Sclerosis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-18 down-regulation
[+]

The administration of probiotic L. casei exerted an anti-inflammatory response in mice fed an high fat diet.Jun 30, 2015

Pubmed Data : Nutrition. 2015 Jul-Aug;31(7-8):1000-7. Epub 2015 Feb 24. PMID: 26059375
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Lactobacillus casei, Probiotics
Diseases : High Fat Diet, Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Cytokine Modulation
[+]

The combination of Astragalus membranaceus extract and ligustrazine to improve the inflammation in rats with thrombolytic cerebral ischemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419869055. PMID: 31409163
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Astragalus, Ligustrazine
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

The hydroalcoholic extract of saffron can be considered as a useful strategy in the treatment of type 1 diabetes.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Allergy Asthma Immunol. 2019 Feb ;18(1):38-47. PMID: 30848572
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation
[+]

The protective effects of 18 β-glycyrrhetinic acid on imiquimod-induced psoriasis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2020 ;2020:1980456. Epub 2020 Aug 27. PMID: 32908937
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The study provides scientific reference for artesunate usage in preventing autoimmune liver injury.Apr 30, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 May ;43(10):2123-2128. PMID: 29933681
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Autoimmune Diseases, Chemically-Induced Liver Damage, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

Therapeutic effect of carvacrol-loaded albumin nanoparticles on rheumatoid arthritis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2020 ;19(1):312-320. PMID: 32922489
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Nitric Oxide Inhibitor
[+]

These results may point to noni fruit as an important source of anti-inflammatory molecules.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2017 ;2017:6567432. Epub 2017 Jan 17. PMID: 28194046
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Tocotrienol-rich fraction could serve as a gut health supplement for preventive measures for ulcerative colitis condition in patients.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2019 ;65(4):318-327. PMID: 31474681
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Total glucosides of Paeony effectively improves the symptoms of DSS-induced colitis.May 22, 2021

Pubmed Data : Phytomedicine. 2021 May 23 ;87:153590. Epub 2021 May 23. PMID: 34033998
Article Published Date : May 22, 2021
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-23 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Total glycosides of peony protects against inflammatory bowel disease.Dec 31, 2018

Pubmed Data : Am J Chin Med. 2019 ;47(1):177-201. Epub 2019 Jan 7. PMID: 30612460
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation
Additional Keywords : Phytotherapy
[+]

Vanillin was an effective bioactive compound against psoriatic skin inflammation.Nov 28, 2017

Pubmed Data : J Agric Food Chem. 2017 Nov 29 ;65(47):10233-10242. Epub 2017 Nov 14. PMID: 29073354
Article Published Date : Nov 28, 2017
Study Type : Animal Study
Additional Links
Substances : Vanillin
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

Vitamin D3 supplementation diminished the inflammatory conditions in systemic lupus erythematosus.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2016 Apr ;19(4):374-80. PMID: 27279980
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Zinc deficiency is an important contributing factor in immune aging.Jan 02, 2021

Pubmed Data : Biometals. 2021 Jan 3. Epub 2021 Jan 3. PMID: 33392795
Article Published Date : Jan 02, 2021
Study Type : Animal Study
Additional Links
Substances : Zinc
Diseases : Aging, Inflammation, Zinc Deficiency
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Shikonin inhibits CEBPD downregulation in IL‑17‑treated HaCaT cells and in an imiquimod‑induced psoriasis model.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2020 Sep ;22(3):2263-2272. Epub 2020 Jul 9. PMID: 32705251
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Psoriasis
Pharmacological Actions : Antiproliferative , Interleukin-17 downregulation
[+]

A novel probiotic mixture, slows down the tumor growth significantly and reduces the tumor size and weight by 40% compared with the control.Feb 15, 2016

Pubmed Data : Proc Natl Acad Sci U S A. 2016 Feb 16. Epub 2016 Feb 16. PMID: 26884164
Article Published Date : Feb 15, 2016
Study Type : In Vitro Study
Additional Links
Substances : Probiotics
Diseases : Gastrointestinal Inflammation, Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-17 downregulation
Additional Keywords : Microbiota
[+]

Cannabinoids could be possible agents for treatment of psoriasis. Jan 31, 2017

Pubmed Data : Med Hypotheses. 2017 Feb ;99:15-18. Epub 2016 Dec 14. PMID: 28110689
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Psoriasis
Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Interleukin-17 downregulation, Interleukin-8 downregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Capparis Spinosa L. promotes anti-inflammatory responses in vitro.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Immunol. 2016 ;17(1):26. Epub 2016 Aug 2. PMID: 27483999
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Capparis spinosa (caper)
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-4 upregulation
[+]

CBD treatment may ameliorate experimental autoimmune encephalomyelitis through induction of immunosuppressive myeloid-derived suppressor cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1782. Epub 2018 Aug 3. PMID: 30123217
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-17 downregulation
[+]

Green tea could reduce inflammatory and oxidant patterns in Inflammatory bowel diseases.Mar 31, 2019

Pubmed Data : Complement Ther Med. 2019 Apr ;43:148-153. Epub 2019 Jan 19. PMID: 30935522
Article Published Date : Mar 31, 2019
Study Type : Review
Additional Links
Substances : Green Tea
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Immunomodulatory effects of Lactobacillus plantarum on inflammatory response induced by Klebsiella pneumoniae.Sep 02, 2019

Pubmed Data : Infect Immun. 2019 Sep 3. Epub 2019 Sep 3. PMID: 31481408
Article Published Date : Sep 02, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Klebsiella Infections
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

Narrow-leafed lupin seeds gamma-conglutin is an anti-inflammatory protein promoting insulin resistance improvement and oxidative stress.Dec 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Dec 23 ;9(1). Epub 2019 Dec 23. PMID: 31877933
Article Published Date : Dec 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lupine
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin attenuates allergic inflammation in asthma.Dec 31, 2014

Pubmed Data : Int Immunopharmacol. 2015 Jan ;24(1):88-94. Epub 2014 Nov 26. PMID: 25433342
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-17 downregulation, Interleukin-5 downregulation
[+]

Paeoniflorin suppresses inflammatory response in imiquimod-induced psoriasis.Jul 31, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Aug ;94(8):888-94. Epub 2016 Mar 10. PMID: 27348512
Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin-6'-o-benzene sulfonate (CP-25) improves vasculitis.Oct 01, 2020

Pubmed Data : Phytother Res. 2020 Oct 2. Epub 2020 Oct 2. PMID: 33006176
Article Published Date : Oct 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Rheumatoid Arthritis, Vasculitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, STAT3 Inhibitor
[+]

Resveratrol prevents bisphenol A-induced autism, type 2 diabetes mellitus and metabolic syndrome.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrition. 2016 Feb ;32(2):174-8. Epub 2015 Sep 25. PMID: 26706021
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Autism Spectrum Disorders, Bisphenol-A Toxicity, Diabetes Mellitus: Type 2: Prevention, Metabolic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Interleukin-17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Microbiota, Risk Reduction
Problem Substances : Bisphenol A
[+]

Saikosaponin A may be used as a therapeutic candidate for allergic rhinitis disease.Jan 04, 2020

Pubmed Data : Chem Biol Interact. 2020 Jan 5 ;315:108874. Epub 2019 Oct 24. PMID: 31669322
Article Published Date : Jan 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Saikosaponin
Diseases : Allergic Rhinitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, STAT3 Inhibitor
[+]

Shikonin has anti-inflammatory effects on collagen-induced arthritis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:2428546. Epub 2018 Dec 16. PMID: 30643526
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

These results imply that cucurbitacin E possesses powerful anti-encephalitogenic activity.Jun 21, 2016

Pubmed Data : J Agric Food Chem. 2016 Jun 22 ;64(24):4900-7. Epub 2016 Jun 8. PMID: 27225664
Article Published Date : Jun 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin E
Diseases : Autoimmune Diseases, Encephalitis
Pharmacological Actions : Antioxidants, Interferon Gamma Reducer, Interleukin-17 downregulation, MicroRNA modulator, Nitric Oxide Inhibitor
[+]

These results may explain the antiviral potential of almond skins.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(5):8816-22. Epub 2015 May 15. PMID: 25988612
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Almond
Diseases : Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents, Interleukin-17 downregulation
Additional Keywords : Plant Extracts
[+]

Tocotrienol regulates osteoclastogenesis in rheumatoid arthritis. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Intern Med. 2021 03 ;36(Suppl 1):S273-S282. Epub 2020 Jun 19. PMID: 32550719
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Vitexin protected melanocytes from oxidative stress by activating MAPK-Nrf2/ARE signaling pathway.Nov 02, 2020

Pubmed Data : Immunopharmacol Immunotoxicol. 2020 Nov 3:1-10. Epub 2020 Nov 3. PMID: 33045867
Article Published Date : Nov 02, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Nrf2 activation

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