Interleukin-17 downregulation

Name	AC	CK
Curcumin	3	14
Alpha-Lipoic Acid	2	12
Oleuropein	2	12
Paeoniflorin	7	11
Crocin	1	10
Ligustrazine	3	6
Probiotics	3	5
Berberine	2	4
Hyperforin	2	4
Lactobacillus casei	2	4
Peony	2	4
Cannabidiol	2	3
Vitamin E	2	3
Achiote	1	2
Anthocyanins	1	2
Artesunate	1	2
Astragaloside	1	2
Astragalus	1	2
Barley	1	2
Beta-Caryophyllene	1	2
Black Raspberry	1	2
Bromelain	1	2
Carnosic Acid	1	2
Carnosine	1	2
Carvacrol	1	2
EGCG (Epigallocatechin gallate)	1	2
Evening Primrose Oil	1	2
Fermented Foods and Beverages	1	2
Ferulic acid	1	2
Flavonoids	1	2
Ginseng (Korean)	1	2
Ginsenosides	1	2
Glycyrrhizin	1	2
Gotu Kola	1	2
Grape	1	2
Hemp Seed	1	2
Lactobacillus fermentum	1	2
Lactobacillus rhamnosus	1	2
Lactobacillus salivarius	1	2
Lavender: Essential Oil	1	2
Mangosteen	1	2
Noni	1	2
Okra	1	2
Oridonin	1	2
Parthenolide	1	2
Patchouli	1	2
Perillaldehyde	1	2
Phloretin	1	2
Pomegranate	1	2
Propolis: Bee	1	2
Quercetin	1	2
Raspberry	1	2
Saffron	1	2
Selenium	1	2
Shikonin	2	2
St. Johns Wort	1	2
Sulforaphane	1	2
Sweet Potato: Purple	1	2
Tarragon	1	2
Tetrahydrocurcumin	1	2
Vanillin	1	2
Vitamin D	1	2
Zinc	1	2
Almond	1	1
Cannabinoids	1	1
Capparis spinosa (caper)	1	1
Cucurbitacin E	1	1
Green Tea	1	1
Lactobacillus plantarum	1	1
Lupine	1	1
Resveratrol	1	1
Vitexins	1	1

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Gallic acid diminishes pro-inflammatory interferon-γ- and interleukin-17-producing sub-populations in vitro in patients with psoriasis.May 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-6 Downregulation, STAT3 Inhibitor

Additional Keywords : Phytotherapy

Problem Substances : Arsenic

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Pubmed Data : Sci Rep. 2023 Sep 11 ;13(1):14924. Epub 2023 Sep 11. PMID: 37696876

Article Published Date : Sep 10, 2023

Study Type : Human Study

Additional Links

Diseases : Rheumatoid Arthritis

Therapeutic Actions : Yoga

Pharmacological Actions : Immunomodulatory, Interleukin-17 downregulation, Interleukin-6 Downregulation

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Alantolactone suppresses proliferation and the inflammatory response in human HaCaT keratinocytes.Jun 24, 2021

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Effect of combination treatment with Lactobacillus rhamnosus and corticosteroid in reducing airway inflammation in a mouse asthma model.Apr 22, 2022

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Fermented milk appears to potentially play a role in decreasing the Th17 response.Aug 07, 2018

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Pubmed Data : Nutrients. 2018 Aug 8 ;10(8). Epub 2018 Aug 8. PMID: 30096797

Article Published Date : Aug 07, 2018

Study Type : Animal Study

Additional Links

Substances : Lactobacillus fermentum

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation

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Ferulic acid altered IL-17A/IL-17RA interaction and protected against imiquimod-induced psoriasis-like skin injuryJun 30, 2019

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Pubmed Data : Food Chem Toxicol. 2019 Jul ;129:365-375. Epub 2019 May 3. PMID: 31054998

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Pubmed Data : Biomed Pharmacother. 2019 Feb ;110:692-699. Epub 2018 Dec 12. PMID: 30553196

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Glycyrrhizin

Diseases : Hepatitis: Lectin-Induced (concanavalin)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation

Problem Substances : Concanavalin A

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Glycyrrhizin improves the pathogenesis of psoriasis.May 26, 2021

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Pubmed Data : Chin J Integr Med. 2018 May ;24(5):353-358. Epub 2017 Oct 30. PMID: 29086220

Article Published Date : Apr 30, 2018

Study Type : Animal Study

Additional Links

Substances : Ligustrazine

Diseases : Asthma

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation

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Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats.Mar 14, 2021

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Pubmed Data : Life Sci. 2021 Mar 15 ;269:119008. Epub 2021 Jan 9. PMID: 33434535

Article Published Date : Mar 14, 2021

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Inflammation, Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation, NF-kappaB Inhibitor

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Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.Nov 30, 2018

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Pubmed Data : Pharm Biol. 2018 Dec ;56(1):455-464. PMID: 31070537

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Pubmed Data : Adv Pharmacol Sci. 2018 ;2018:8505383. Epub 2018 Oct 9. PMID: 30402093

Paeoniflorin ameliorates experimental autoimmune encephalomyelitis.Jan 05, 2017

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Pubmed Data : Arthritis Rheum. 2010 Jan;62(1):159-70. PMID: 20039434

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Supplementation with tetrahydrocurcumin enhances the therapeutic effects of dexamethasone in a murine model of allergic asthma.Dec 31, 2019

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Pubmed Data : Int Arch Allergy Immunol. 2020 ;181(11):822-830. Epub 2020 Aug 12. PMID: 32784298

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Pubmed Data : Mediators Inflamm. 2017 ;2017:6567432. Epub 2017 Jan 17. PMID: 28194046

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Noni

Diseases : Colitis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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Tocotrienol-rich fraction could serve as a gut health supplement for preventive measures for ulcerative colitis condition in patients.Dec 31, 2018

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Pubmed Data : Proc Natl Acad Sci U S A. 2016 Feb 16. Epub 2016 Feb 16. PMID: 26884164

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Pubmed Data : Front Immunol. 2018 ;9:1782. Epub 2018 Aug 3. PMID: 30123217

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-17 downregulation

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Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.Jan 18, 2022

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Pubmed Data : Front Pharmacol. 2021 ;12:700696. Epub 2021 Sep 1. PMID: 34539397

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Acne

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation

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Kaempferol modulates IFN-γ induced JAK-STAT signaling pathway and ameliorates imiquimod-induced psoriasis.Dec 14, 2022

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Pubmed Data : Nutrition. 2016 Feb ;32(2):174-8. Epub 2015 Sep 25. PMID: 26706021

Article Published Date : Jan 31, 2016

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View the Evidence: 156 Abstracts with Interleukin-17 downregulation Research

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Gallic acid diminishes pro-inflammatory interferon-γ- and interleukin-17-producing sub-populations in vitro in patients with psoriasis.May 31, 2023

Combining nano-curcumin with catechin improves COVID-19-infected patient's inflammatory conditions.Aug 31, 2023

Effects of standardized Brazilian green propolis extract on inflammation in haemodialysis patients.Dec 31, 2021

Electroacupuncture could effectively reduce the suffering and improve the quality of life of rheumatoid arthritis patients.Jul 31, 2019

Electroacupuncture for acute ischemic stroke and its effect on plasma levels of IL-17 and IL-10.Aug 11, 2022

Ginkgo biloba extract attenuates the disruption of pro- and anti-inflammatory balance of peripheral blood in arsenism patients.Nov 30, 2022

Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations.Jan 13, 2021

Lipoic acid down-regulates inflammation in multiple sclerosis patients.Jan 01, 2010

Potential value and mechanism of Rosa roxburghii tratt juice on pro-inflammatory responses in peripheral blood of patients with arsenic poisoning.Dec 31, 2021

Selenium supplementation as add-on therapy with medical management induced remission and improved the quality of life in patients with active mild-to-moderate UC.Nov 30, 2023

The effectiveness of BIFIFORM KIDS in the prevention of the incidence of acute respiratory infections in children.Dec 31, 2021

These new data support a potential role of oleuropein in the treatment of ulcerative colitis.Apr 14, 2017

These results suggest the beneficial and therapeutic effects of crocin in multiple sclerosis.Oct 15, 2019

Transmucosal administration of microgranular curcumin leads to enhanced curcumin bioavailability.Nov 30, 2015

Vitamin D modulates systemic inflammation in patients with severe COVID-19.Aug 23, 2022

Yoga maintains Th17/Treg cell homeostasis and reduces the rate of T cell aging in rheumatoid arthritis.Sep 10, 2023

Lactobacillus casei could act as a potent nutraceutical modulator forosteoarthritis treatment by reducing pain, inflammatory responses, and articular cartilage degradation.Dec 16, 2010

3, 3'- diindolylmethane hinders IL-17A/IL-17RA interaction and mitigates imiquimod-induced psoriasis.Jul 31, 2022

A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.May 10, 2020

Acteoside promotes B cell-derived IL-10 production and ameliorates autoimmunity.Sep 30, 2022

Administering curcumin may alleviate cerebral inflammation resulting from intracerebral hemorrhage.Mar 25, 2016

Administration of Epigallocatechin-3-gallate resulted in a significant reduction in bone loss.Sep 06, 2015

Aerobic training and royal jelly improved inflammatory and regulatory factors of autoimmunity and reduced anxiety and depression.Jan 19, 2023

Alantolactone suppresses proliferation and the inflammatory response in human HaCaT keratinocytes.Jun 24, 2021

Anti-inflammatory effect a specific Lactiplantibacillus plantarum in an Ovalbumin-induced asthma model.Jun 07, 2022

Anti-psoriatic effect of Lavandula angustifolia essential oil and its major components linalool and linalyl acetate.Jul 01, 2020

Artemisia dracunculus L. modulates the immune system in a multiple sclerosis mouse model.Oct 30, 2019

Artemisinin alleviates intestinal inflammation and metabolic disturbance in ulcerative colitis rats induced by DSS.Dec 31, 2021

Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions.Feb 29, 2016

Astragaloside IV ameliorates experimental autoimmune myasthenia gravis.Aug 03, 2023

Astragaloside IV stimulates hippocampal neurogenesis after stroke.Dec 31, 2019

Berberine as a promising natural compound for the treatment of periodontal disease.Oct 29, 2021

Berberine attenuates arthritis in adjuvant-induced arthritis.Feb 19, 2019

Berberine exerted a superior anti-arthritic effect and the mechanism maybe involve the balance between Treg and Th17 cells.Mar 05, 2017

Beta-Caryophyllene ameliorates the development of experimental autoimmune encephalomyelitis.Apr 28, 2017

Bixin attenuates experimental autoimmune encephalomyelitis. Dec 31, 2019

Black raspberries and protocatechuic acid mitigate DNFB-induced contact hypersensitivity.Jun 05, 2020

Bromelain has a therapeutic effect in established allergic airway disease.Aug 31, 2012

Cannabidiol was found to promote neuronal survival by inhibiting JNK and p38 MAP kinases.Nov 24, 2016

Capsaicin attenuates imiquimod-induced epidermal hyperplasia and cutaneous inflammation in a murine model of psoriasis.Aug 31, 2021

Celastrol attenuates Guillain-Barré syndrome.Dec 31, 2022

Chrysin reduces hypercholesterolemia-mediated atherosclerosis through modulating oxidative stress, microflora, and apoptosis in experimental rats.Jul 26, 2022

Curcumin ameloriates experimental autoimmune encephalomyelitis through inhibition of IL-17 production.May 01, 2009

Dietary red raspberries attenuate dextran sulfate sodium-induced acute colitis.Dec 31, 2017

Dietary selenium supplementation alleviates immune toxicity in the hearts of chickens with lead-added drinking water.May 31, 2019

Diosgenin could be a good candidate for new MS treatment strategies.Sep 30, 2021

Effect of astaxanthin on neuron damage, inflammatory factors expressions and oxidative stress in mice with subarachnoid hemorrhage.Dec 31, 2020

Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease.Dec 31, 2019

Effect of carvacrol on histological analysis and expression of genes involved in an animal model of multiple sclerosis.Dec 15, 2022

Effect of combination treatment with Lactobacillus rhamnosus and corticosteroid in reducing airway inflammation in a mouse asthma model.Apr 22, 2022

Effect of electroacupuncture on expression of IL-23/IL-17 axis and TLR4 in infarcted tissue in rats with myocardial infarction.Sep 11, 2021

Effects of Astragalus membranaceus on systemic lupus erythematosus in a mouse model of pregnancy.May 31, 2022

Effects of naringenin on experimentally induced rheumatoid arthritis. Sep 30, 2021

EGCG improved lung damage in P. aeruginosa infection by inhibiting the production.Dec 31, 2021

Enteral exposure to P histicola suppresses arthritis via mucosal regulation.Jan 11, 2016

Fermented barley extract alleviates atopic dermatitis like skin lesions in NC/Nga mice.Mar 22, 2009

Fermented milk appears to potentially play a role in decreasing the Th17 response.Aug 07, 2018

Ferulic acid altered IL-17A/IL-17RA interaction and protected against imiquimod-induced psoriasis-like skin injuryJun 30, 2019

Fucoxanthin prevents the ovalbumin-induced food allergic response by enhancing the intestinal epithelial barrier and regulating the intestinal flora.Aug 09, 2022

Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation.Jun 30, 2021

Ginseng-derived panaxadiol ameliorates STZ-induced type 1 diabetes.May 31, 2023

Ginsenoside F2 may be a novel therapeutic approach for treating skin inflammation.Sep 29, 2016

Glycyrrhizin alleviates Con A-induced hepatitis.Jan 31, 2019

Glycyrrhizin improves the pathogenesis of psoriasis.May 26, 2021

Hemp seed and evening primrose oils treatment can be used to ameliorate the demyelination of spinal cord.Mar 31, 2019

Hyperforin could promote functional recovery when delivered in the later phases of stroke recovery.Aug 31, 2016

Hyperforin could protect against acute cerebral ischemic injury.Dec 31, 2017

Inhibitory effect of Centella asiatica extract on DNCB-induced atopic dermatitis.Feb 04, 2020

KGC3P attenuates ovalbumin-induced airway inflammation through downregulation of p-PTEN in asthmatic mice.Apr 29, 2019

Lactobacillus salivarius LA307 and Lactobacillus rhamnosus LA305 attenuate skin inflammation.Feb 26, 2018

Licorice protects against ulcerative colitis via the Nrf2/PINK1-mediated mitochondrial autophagy.Dec 31, 2022

Ligustrazine could alleviate the airway inflflammation in the neutrophilic asthma mice model.Apr 30, 2018

Interleukin-17 downregulation

View the Evidence:
156 Abstracts with Interleukin-17 downregulation Research