Interleukin-6 Downregulation

Name	AC	CK
Curcumin	74	162
Probiotics	21	137
Vitamin C	22	133
Coenzyme Q10	14	130
Berberine	43	93
Ginsenosides	41	77
Flavonoids	38	63
Resveratrol	34	62
Vitamin D	16	62
Flaxseed	6	54
Omega-3 Fatty Acids	7	53
Pomegranate	11	52
Thymoquinone	22	52
Lycopene	14	51
Paeoniflorin	29	51
Polyphenols	30	50
Vitamin E	8	48
Astaxanthin	20	45
Melatonin	7	45
Spirulina	8	41
Luteolin	22	40
Quercetin	25	40
Garlic	6	38
Alpha-Lipoic Acid	5	36
Astragaloside	24	36
NAC (N-acetyl-L-cysteine)	5	36
Puerarin	16	36
EGCG (Epigallocatechin gallate)	15	35
Ginger	18	34
Anthocyanins	14	33
Lactobacillus plantarum	10	33
Tanshinone IIA	22	32
Tomato	3	31
Green Tea	16	30
Nigella sativa (aka Black Seed)	7	29
Citrus naringin	17	28
Diosmin	10	27
Fish Oil	4	26
Garlic: Aged	4	26
Red Sage	10	26
Fucoidan	10	25
Fucoxanthin	10	25
Paeonol	14	25
Patchouli	15	25
Peony	18	25
Sulforaphane	17	25
Fisetin	11	24
Lactobacillus fermentum	9	24
Rose	16	24
Sesame Seeds	5	24
Sesamin	5	24
Strawberry	4	24
Turmeric	11	24
Genistein	10	23
Hesperidin	13	23
Purslane	13	23
Burdock	7	22
Gastrodin	8	22
Almond	3	21
Chrysin	13	21
Lactobacillus rhamnosus GG	7	21
Dandelion	11	20
Isoflavones	2	20
Moringa oleifera	13	20
Soy Protein	2	20
Vitamin B-12	2	20
Crocin	11	19
DHA (Docosahexaenoic Acid)	6	18
Ginkgo biloba	6	18
Asiatic Acid	11	17
Black Currant	5	17
Kaempferol	10	17
Lotus	9	17
Nettle	5	17
Panax Notoginseng	9	17
Phloretin	9	17
Whey	5	17
Apigenin	11	16
Bee Venom	10	16
Black Raspberry	5	16
Cannabidiol	9	16
Cyanidin 3-glucoside	4	16
Ellagic Acid	11	16
Ginseng (Korean)	10	16
Lactobacillus Acidophilus	4	16
Lactobacillus casei	4	16
Lactobacillus probiotics	4	16
Magnolol	8	16
Nobiletin	10	16
Oleuropein	7	16
Olive	5	16
Silibinin	5	16
Vitamin E: alpha tocopherol	4	16
beta-Carotene	4	16
Fermented Foods and Beverages	10	15
Pterostilbene	8	15
Coconut Oil	3	14
Formononetin	8	14
Hydroxytyrosol	3	14
Indole-3-Carbinol	7	14
Lactobacillus reuteri	7	14
Mangiferin	9	14
Olive leaf extract	3	14
Punicalagin	8	14
Rosmarinic acid	6	14
Sea buckthorn	8	14
Tart Cherry	3	14
Apple	3	13
Ashwagandha	8	13
Astragalus	3	13
Beta-glucan	3	13
Caffeic acid phenethyl ester	3	13
Cardamonin	3	13
Chokeberry	8	13
Ginseng	5	13
Grape Seed Extract	7	13
Honeysuckle	8	13
Honokiol	7	13
Ligustrazine	7	13
Lychee	5	13
Vitexins	5	13
Yoghurt	3	13
Allicin	7	12
Baicalein	6	12
Biochanin A	7	12
Blueberry	8	12
Carnosic Acid	6	12
Emodin	7	12
Ferulic acid	7	12
Flaxseed Oil	2	12
Honey	2	12
Mastic gum	2	12
Myricetin	8	12
Nuts	3	12
Olive Oil	2	12
Pomegranate Peel	2	12
Porridge	2	12
Pumpkin Seeds	2	12
Tocotrienols	2	12
Yerba Mate	2	12
Boswellia	2	11
Chrysanthemum Indicum	6	11
Gallic Acid	6	11
Lactobacillus delbrueckii Subsp	2	11
Lutein	2	11
Magnesium	2	11
Mulberry	6	11
P-Coumaric Acid	6	11
Royal Jelly	2	11
Safflower	6	11
Zataria multiflora	2	11
Antioxidant formulas	1	10
Bacillus coagulans	1	10
Bilberry	1	10
Broccoli Sprouts	1	10
Carnitine	1	10
Carnosol	4	10
Chlorogenic Acid	5	10
Chocolate	1	10
Cruciferous Vegetables	1	10
Delphinidin	1	10
Fiber	1	10
Folate	1	10
Folic Acid	1	10
Gotu Kola	6	10
Hydrogen Water	5	10
Isothiocyanate	1	10
Isothiocyanates	6	10
Lactobacillus paracasei	5	10
Marshmallow Root	1	10
Naringenin	6	10
Raisins	1	10
Resistant Starch	1	10
Selenium	6	10
Soup	1	10
Thunder god vine	1	10
Tripterygium wilfordii	1	10
Ubiquinol	1	10
Vitamin A	1	10
Water: Electrolyzed Reduced	1	10
Adlay	6	9
Betulinic acid	6	9
Dogwood	6	9
Genipin	5	9
Guduchi	5	9
Isoliquiritigenin	5	9
Kefir	5	9
Lactobacillus rhamnosus	5	9
Lactoferrin	6	9
Raspberry	5	9
Rosemaric Acid	6	9
Stilbenes	5	9
Agaricus Blazei	4	8
Aloe Vera	4	8
Bamboo	3	8
Eugenol	3	8
Gingerol	5	8
Goji	5	8
Hops	5	8
Piceatannol	6	8
Piperine	5	8
Saffron	5	8
Shikonin	5	8
Sweet Potato: Purple	5	8
Tangeretin	5	8
White Tea	4	8
Wogonin	6	8
6-Shogaol	4	7
Arctigenin	4	7
Bitter Melon	5	7
Black Tea	4	7
Cinnamaldehyde	3	7
Diosgenin	4	7
Echinacea	5	7
Eriodictyol	5	7
Fig	2	7
Frankincense	5	7
Glycyrrhizin	4	7
Licorice	4	7
Lion's Mane (Hericium Erinaceus)	4	7
Manuka Honey	5	7
Oleanolic acid	4	7
Oridonin	5	7
Vanillin	5	7
Alpha Linolenic Acid	3	6
Artesunate	3	6
Beta-Elemene	4	6
Celastrol	4	6
Citral	3	6
Crocetin	4	6
Eucalyptus	3	6
Gold (nanoparticles)	3	6
Hibiscus sabdariffa	3	6
Histidine	3	6
Hu Zhang (Polygonum cuspidatum)	3	6
Lignans	4	6
Parthenolide	4	6
Procyanidin B2	4	6
Propolis: Brazillian	3	6
Reishi Mushroom	5	6
Rooibos	3	6
Rutin	4	6
Schisandra	3	6
Verbascoside	4	6
Yellow Tea	3	6
Artichoke	3	5
Bergamot	3	5
Bitter Apple	3	5
Bitter Orange	4	5
Citrus Peel	3	5
Diosmetin	1	5
Geraniol	3	5
Hemp Seed	4	5
Japanese cypress	3	5
Maitake Mushroom	3	5
Niacinamide	1	5
Oleocanthal	1	5
Perilla	3	5
Persimmon	3	5
Sesamol	3	5
Zerumbone	3	5
Acai	2	4
Amygdalin	2	4
Bael	2	4
Beans: All	2	4
Bee Pollen	2	4
Bee Propolis	4	4
Beta-Caryophyllene	3	4
Bifidobacterium Lactis	2	4
Bifidobacterium Longum	2	4
Blackberry	2	4
Brown Rice: Pre-Germinated	2	4
Camel Milk	2	4
Carnosine	2	4
Carvacrol	4	4
Catechin	2	4
Chinese Skullcap	2	4
Cocoa	2	4
Cordyceps Militaris	2	4
Cordyceps sinensis	2	4
Corn: Purple	2	4
Cranberry	2	4
EPA (Eicosapentaenoic Acid)	2	4
FOS (Fructooligosaccharides)	2	4
Huperzine	2	4
Kimchi	3	4
Liquiritigenin	3	4
Lupeol	2	4
Medicinal Mushrooms	3	4
Oligonol	2	4
Oolong tea	2	4
Perillaldehyde	2	4
Piperlongumine	3	4
Propolis: Bee	2	4
Prunella vulgaris	2	4
Purple Carrots	3	4
Red Yeast Rice	2	4
Rice	2	4
Seaweed: Brown	2	4
Shiitake Mushroom	2	4
Silymarin	2	4
Soy	2	4
St. Johns Wort	2	4
Ursolic Acid	3	4
Xanthohumol	2	4
Angelica	2	3
Apple Cider Vinegar	2	3
Bacopa	2	3
Banana	2	3
Barley	2	3
Bromelain	2	3
Carrot	2	3
Chamomile	2	3
Chia	2	3
Chlorella (Algae)	2	3
Cucurbitacin B	2	3
Curcumin: Degradiation byproducts	2	3
Garcinia Mangostana	2	3
Hawthorn	2	3
Hibiscus	3	3
Jujube	2	3
Justicia gendarussa	2	3
Kiwifruit	2	3
Loquat Leaves	2	3
MSM (Methylsulfonylmethane)	2	3
Mint	2	3
Myrrh	2	3
Oats	2	3
Oligosaccharides	2	3
Pine Needle	3	3
Pistachio nut	2	3
Plantago	2	3
Quince	2	3
Red Clover	2	3
Red Marine Algae	2	3
Safranal	2	3
Salvia miltiorrhiza	2	3
Sarsaparilla	2	3
Silver (nanoparticles)	2	3
Soybean: Black	2	3
Theaflavins	2	3
Theanine	2	3
Thyme	2	3
Thymol	2	3
Urolithin A	2	3
Vitex negundo	2	3
Walnut	2	3
Wheat Germ	2	3
White Mulberry	3	3
Zeaxanthin	2	3
5-HTP (5-Hydroxytryptophan)	1	2
ALA (Alpha-Linolenic Acid)	1	2
Aduki bean	1	2
African Basil	1	2
Amla Fruit	1	2
Antrodia Camphorate	1	2
Apocynin	1	2
Arginine	1	2
Banaba	1	2
Banana Leaf	1	2
Barberry	1	2
Basil	1	2
Basil: Sweet	2	2
Bay Laurel	1	2
Beta Sitosterol	1	2
Bifidobacterium	1	2
Bifidobacterium Bifidum	1	2
Bifidobacterium Breve	1	2
Bifidobacterium Infantis	1	2
Billygoat Weed	1	2
Black Pepper	2	2
Blue Honeysuckle	1	2
Boron	1	2
Brown Rice	1	2
Buckwheat	1	2
Bufalin	1	2
Butyrate	1	2
Caffeic Acid	1	2
Carotenoids	2	2
Celadrin	1	2
Chaenomeles speciosa	1	2
Chaga Mushroom (Inonotus obliquus)	1	2
Cinnamon	1	2
Citrulline	1	2
Coffee: Green/Unroasted	1	2
Common bean	1	2
Cystine	1	2
Daidzein	2	2
Diallyl sulfide	1	2
Dill	1	2
Dong Quai	1	2
Elderberry	1	2
Elm tree	1	2
Evening Primrose Oil	1	2
Galactooligosaccharides	1	2
Garden Cress (Lepidium sativum)	1	2
Grape	1	2
Gymnema Sylvestre	1	2
Helenalin	1	2
Honeydew (melon)	1	2
Kaempferia parviflora	1	2
Krill	1	2
L-Carnitine	1	2
L-arginine	1	2
Lactobacillus Brevis	1	2
Lactobacillus gasseri	2	2
Lactobacillus sakei	1	2
Lactobacillus salivarius	1	2
Lemon Verbena	1	2
Litchi	1	2
Lobelia	1	2
Loquat	1	2
Maca	1	2
Mangosteen	1	2
Milk Thistle	1	2
Milk: Fermented	1	2
Mosla scabra	1	2
Motherwort	2	2
Moxibustion	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Mussel: Green-lipped (Perna canaliculus)	1	2
Nattokinase	1	2
Neem	1	2
Noni	1	2
Onion	1	2
Orange	1	2
Orthosiphon	1	2
Palmitoylethanolamide	1	2
Pectin	1	2
Peppermint	1	2
Phellinus Linteus	2	2
Phlorotannins	1	2
Phosphatidylcholine	1	2
Phytosterols	1	2
Pine Nut	1	2
Piper cubeba (Cubeb)	1	2
Plantago asiatica	1	2
Potato	1	2
Riboflavin (Vitamin B-2)	2	2
Rosemary	2	2
Satsuma	1	2
Seaweed	1	2
Sembung Leaf	1	2
Sesame Seed Oil	1	2
Sour Cherry	2	2
Spikenard	2	2
Stevia	1	2
Suma (Pfaffia Paniculata)	1	2
Sweet Lime	1	2
Taurine	1	2
Tea	1	2
Tetrahydrocurcumin	1	2
Thistle	2	2
Tualang Honey	1	2
Turkey Tail Mushroom	2	2
Velvet antler	1	2
Vitamin B-6	1	2
Vitamin K	1	2
Vitamin K2: (MK-4)	1	2
Water: Deuterium Depleted	1	2
Xanthones	1	2
Yarrow	1	2
Yeast	1	2
acetyl-11-keto-beta-boswellic acid	1	2
Acorus calamus	1	1
Agrimony	1	1
Amino Acids	1	1
Amygdalin (laetrile)	1	1
Andrographis	1	1
Antrodia camphorata	1	1
Apple Pectin	1	1
Avocado	1	1
Ayahuasca	1	1
Babchi	1	1
Bai Zhu	1	1
Berbamine	1	1
Bifidobacterium animalis	1	1
Bisdemethoxycurcumin	1	1
Caffeoylquinic Acids	1	1
Celery seed	1	1
Cherry: All Varieties	1	1
Chrysanthemum Morifolium	1	1
Citric Acid	1	1
Coconut	1	1
Coffee	1	1
Coriandrum sativum	1	1
Cranberry Proanthocyanidins	1	1
Cryptomeria japonica	1	1
Cucumber	1	1
Cucurbitacin E	1	1
Curcumin: Lipidated	1	1
Damnacanthal	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Devils Claw	1	1
False Black Pepper	1	1
Feverfew	1	1
Fruit: All	1	1
Gynostemma	1	1
Haritaki (Terminalia chebula)	1	1
Hazelnut	1	1

[+]

Alpha-lipoic acid supplementation had beneficial effects on inflammatory markers among patients with metabolic syndrome and related disorders.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Dairy Sci. 2019 Nov 27. Epub 2019 Nov 27. PMID: 31785874

Article Published Date : Nov 26, 2019

Study Type : Meta Analysis

Additional Links

Substances : Probiotics

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Effects of probiotic supplementation on respiratory infection and immune function in athletes.Jan 21, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Supplementation

[+]

A hydro alcoholic extract of nettle could decrease the levels of IL-6 and hs-CRP in patients with type 2 diabetes.Jul 31, 2011

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Pubmed Data : Pak J Biol Sci. 2011 Aug 1 ;14(15):775-9. PMID: 22303583

Article Published Date : Jul 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur J Appl Physiol. 2003 May ;89(3-4):393-400. Epub 2003 Apr 1. PMID: 12682838

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Pubmed Data : J Nutr. 2008 Apr ;138(4):732-9. PMID: 18356328

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Substances : Fiber

Diseases : Adiponectin: Low Levels, Inflammation, Insulin Resistance

Pharmacological Actions : Adiponectin upregulation, Interleukin-6 Downregulation

Problem Substances : Insulin

[+]

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

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Pubmed Data : Neurol Sci. 2017 May ;38(Suppl 1):173-175. PMID: 28527073

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Diseases : Headache: Migraine, Inflammation

Therapeutic Actions : Meditation , Mindfullness Training

Pharmacological Actions : Analgesics, Interleukin-6 Downregulation

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Mindfulness meditation training is associated with improvements in a marker of inflammatory disease risk.Jun 30, 2016

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Pubmed Data : Biol Psychiatry. 2016 Jul 1 ;80(1):53-61. Epub 2016 Jan 29. PMID: 27021514

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Antioxidants (Basel). 2021 Jun 25 ;10(7). Epub 2021 Jun 25. PMID: 34202133

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Pubmed Data : Ann Surg. 2006 Nov;244(5):706-14. PMID: 17060763

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Lactobacillus casei, Lactobacillus probiotics, Probiotics

Diseases : Biliary Obstruction , Biliary Tract Diseases, Liver Cancer

Pharmacological Actions : Interleukin-6 Downregulation

[+]

Phototherapy can be an important tool in the obesity, mostly considering its potential effects associated to exercise training in attenuating inflammation in women.May 09, 2015

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Pubmed Data : Lasers Med Sci. 2015 May 10. Epub 2015 May 10. PMID: 25958170

Punicalagin might be one of natural therapeutic compounds for relieving rheumatoid arthritis progression.Dec 31, 2020

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Pubmed Data : Asian J Anesthesiol. 2020 Mar 1 ;58(1):35-44. Epub 2020 Mar 26. PMID: 33081432

Article Published Date : Feb 29, 2020

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Cardiac Surgery, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation

[+]

The roles of physical activity and inflammation in mortality, cognition, and depressive symptoms among older Mexican Americans.Oct 31, 2019

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Pubmed Data : Am J Epidemiol. 2019 Nov 1 ;188(11):1944-1952. PMID: 31497846

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia, Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Physical Activity

[+]

The use of black raspberry improved cardiovascular risks in patients with metabolic syndrome during the 12-week follow-up.Mar 31, 2016

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Additional Keywords : Significant Treatment Outcome

[+]

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

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Pubmed Data : Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID: 25253919

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Pneumonia

Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin C supplementation prevented endurance exercise-induced lipid peroxidation and muscle damage but had no effect on inflammatory markers.May 31, 2008

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Pubmed Data : J Sports Med Phys Fitness. 2008 Jun ;48(2):217-24. PMID: 18427418

Article Published Date : May 31, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Lipid Peroxidation

Therapeutic Actions : Exercise

Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation

[+]

Vitamin D administration can significantly reduce the IL-6 as prognostic marker in ventilator-associated pneumonia patients.Sep 11, 2017

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Pubmed Data : J Crit Care. 2017 Sep 12 ;44:300-305. Epub 2017 Sep 12. PMID: 29248753

Article Published Date : Sep 11, 2017

Study Type : Human Study

Additional Links

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Alpha-lipoic acid supplementation had beneficial effects on inflammatory markers among patients with metabolic syndrome and related disorders.Dec 31, 2017

Coenzyme Q10 could have significant inflammatory lowering effects.Feb 04, 2017

Coenzyme Q10 supplementation may partly improve the process of inflammatory state.Dec 31, 2016

Dietary probiotics are effective in improving the symptoms of inflammatory bowel disease.Nov 26, 2019

Effects of probiotic supplementation on respiratory infection and immune function in athletes.Jan 21, 2021

Flaxseed supplementation may improve some circulating concentrations of specific adhesion molecules and inflammatory cytokines.Nov 14, 2019

Garlic supplementation reduces circulating C-reactive protein, tumor necrosis factor, and interleukin-6 in adults.Mar 31, 2019

Meta-analysis: curcumin down-regulates inteleukin-6. Jul 04, 2016

Mind-body therapies reduce markers of inflammation and influence virus-specific immune responses to vaccination.Dec 31, 2013

Probiotic supplementation significantly reduced serum concentrations of pro-inflammatory cytokines.Mar 10, 2019

Probiotics lowered pro-inflammatory cytokines IL-6 in rheumatoid arthritis.Sep 14, 2017

Prolonged vitamin C supplementation has some modest beneficial effects on recovery from unaccustomed exercise.Nov 30, 2001

Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension.Apr 30, 2017

Supplementation of fish oil may reduce the circulating levels of TNF-α, IL-1 and IL-6 in patients with chronic heart failure.Dec 31, 2011

The effects of NAC on amending TNF-α and IL-6 levels were significant after sensitivity analysis.Jul 25, 2020

The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction.Feb 29, 2020

The present review provides the evidence of LLLT-dependent reduction of IL-1β, TNF-α, and MMP-13.Aug 23, 2020

This meta-analysis showed the promising effect of melatonin administration on reducing CRP and IL-6 among patients with MetS and related disorders.Jun 14, 2018

This suggests that CQ10 supplementation likely attenuates subclinical inflammation.Aug 24, 2017

Tomato products and lycopene supplementation have positive effects on blood lipids, blood pressure and endothelial function.Jan 12, 2017

Vitamin C supplementation attenuates the oxidative stress and inflammatory response to a single bout of exercise.Mar 10, 2020

A combination of gastrodin, folate, and vitamin-B12 in addition to standard antiepileptic treatment can effectively control epileptic seizures.Oct 31, 2017

A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levelsDec 31, 2013

A hydro alcoholic extract of nettle could decrease the levels of IL-6 and hs-CRP in patients with type 2 diabetes.Jul 31, 2011

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

Active polymyalgia rheumatica is characterized by increased serum levels of Interleukin-6 probably originating in inflamed tissue. Mar 01, 2009

Adherence to the mediterranean diet is inversely associated with inflammation (circulating interleukin-6) among middle-aged men. Jan 15, 2008

Aged garlic extract inhibits coronary artery calcification progression, lowers IL–6, glucose levels and blood pressure.Apr 28, 2020

Aged garlic extract may be beneficial in preventing the development of chronic diseases associated with low-grade inflammation.Dec 31, 2017

An anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.Aug 31, 2013

An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients. Jun 01, 2005

Annatto carotenoids attenuate oxidative stress and inflammatory response after high-calorie meal in healthy subjects.Jan 09, 2017

Anti-inflammatory effects of diet and caloric restriction in metabolic syndrome.Mar 07, 2021

Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.Oct 11, 2020

Association of endodontic infection with detection of an initial lesion to the cardiovascular system.Nov 30, 2011

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astragalus improves cardiac function in aged patients with Chronic Heart Failure.Sep 01, 2005

Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome.Jun 30, 2014

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Berberine possesses potential lipid-regulating, antiarthritis, and synovial hyperplasia inhibition activities against rheumatoid arthritis.Dec 31, 2018

Berberine promoted myocardial protection of postoperative patients through regulating myocardial autophagy.Aug 31, 2018

Beta-glucan modulates waist circumference and inflammation in obese subjects.Mar 04, 2017

Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology.Sep 30, 2016

Burdock root tea improves inflammatory status and oxidative stress in patients with knee osteoarthritis.Oct 27, 2014

Cardamonin is a potential candidate for controlling inflammation during primary Sjögren's syndrome.Mar 31, 2018

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Chaihu Shihuang soup can significantly regulate cytokine and improve early recovery of severe acute pancratitis.May 31, 2009

Children and adolescents with ADHD who received Lactobacillus rhamnosus GG supplementation reported better health-related quality of life.Dec 31, 2019

Chronic ingestion of acrylamide-containing products (potato chips) induces a proinflammatory state, a risk factor for progression of atherosclerosis.Mar 01, 2009

Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime.Jul 01, 2002

Coenzyme Q10 might have a role as a good supplement in young children with Down syndrome to ameliorate the neurological symptoms.Oct 18, 2016

Coenzyme Q10 supplementation could be effective in ameliorating inflammatory cytokine levels caused by breast cancer.Dec 31, 2018

Combined therapy regulates the inflammatory process and oxidative stress and contributes to immune protection on patients with T2D.May 07, 2018

Consumption of black currant nectar prior to and after a bout of eccentric exercise attenuates muscle damage and inflammation.Dec 31, 2015

Consumption of cruciferous and apiaceous vegetables reduced circulating IL-6.Oct 31, 2014

Consumption of pomegranate peel extract in combination with vitamin E enhanced the inflammatory status and endothelial function in hemodialysis patients.Aug 24, 2020

CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.Apr 30, 2015

Curcumin and Boswellia serrata are safe and tolerable and helped to improvethe levels of an inflammatory cytokine (IL-6).Dec 31, 2012

Curcumin supplementation effectively mitigates inflammation in patients suffering from chronic SM-induced cutaneous complications. Oct 31, 2012

Curcumin supplementation significantly decreases serum concentrations of pro-inflammatory cytokines in subjects with MetS.Jun 05, 2016

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

Daily supplementation of coenzyme Q10 can be effective in decreasing some pro-inflammatory factors in hypertensive patients. Nov 30, 2015

Dark chocolate has beneficial effects on serum adiponectin, biochemical and inflammatory parameters in diabetic patients.Dec 31, 2017

Defatted flaxseed flour improves weight loss and lipid profile in overweight and obese adults.Sep 22, 2020

Dietary soy improves the inflammatory and nutritional status in end-stage renal disease patients on chronic hemodialysisAug 01, 2006

Dietary strawberries may have significant analgesic and anti-inflammatory effects in obese adults with established knee osteoarthritis.Aug 27, 2017

Dietary supplementation with pressurized whey may potentiate the effects of exercise training on exercise tolerance and quality of life in patients with COPD.Jun 01, 2010

Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.Sep 11, 2019

Effect of yoga therapy on disease activity, inflammatory markers, and heart rate variability in patients with rheumatoid arthritis.Apr 22, 2020

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

Either free radicals are not involved in delaying the recovery process following a bout of unaccustomed exercise or the consumption of VitaminC wholly after exercise is unable to deliver this antioxidant to the appropriate sites with sufficient expediencyApr 30, 2003

Electroacupuncture can effectively decrease the proinflammatory cytokine of IL-1 and IL-6 and increase the inhibition cytokine of IL-4 and IL-10 and improve the internal environment of occurrence and progression of rheumatoid arthritis.Oct 01, 2010

Interleukin-6 Downregulation

View the Evidence:
2108 Abstracts with Interleukin-6 Downregulation Research