Interleukin-8 downregulation

Name	AC	CK
Curcumin	17	34
Lactobacillus plantarum	4	23
Lactobacillus Acidophilus	4	22
Probiotics	3	21
Coenzyme Q10	2	20
Omega-3 Fatty Acids	2	20
Olive leaf extract	3	14
Quercetin	5	14
Black Tea	3	12
EGCG (Epigallocatechin gallate)	7	12
Lactobacillus paracasei	2	12
Milk Thistle	2	12
Red Sage	2	12
Vitamin D	3	12
Whey	2	12
Fermented Foods and Beverages	2	11
Fisetin	2	11
Bifidobacterium Bifidum	1	10
Ginkgo biloba	1	10
Japanese cypress	1	10
Lactobacillus casei	1	10
Lactobacillus fermentum	1	10
Mango	1	10
Porridge	1	10
Silibinin	1	10
Tea Tree	1	10
Zataria multiflora	1	10
Punicalagin	3	7
Flavonoids	4	6
Lotus	2	6
Phloretin	2	6
Resveratrol	4	6
Citral	1	5
Diosmetin	1	5
Niacinamide	1	5
Rosmarinic acid	1	5
Turmeric	4	5
Celastrol	3	4
Dandelion	3	4
Eriodictyol	3	4
Ginsenosides	3	4
Allicin	2	3
Astaxanthin	3	3
Berberine	3	3
Betulinic acid	2	3
Cannabidiol	2	3
Chokeberry	3	3
Feverfew	2	3
Frankincense	2	3
Oats	2	3
Polyphenols	3	3
Rose	2	3
Theaflavins	2	3
Astragaloside	2	2
Babchi	1	2
Biochanin A	1	2
Bitter Melon	1	2
Cardamonin	1	2
Carnosic Acid	1	2
Carrot	2	2
Carvacrol	2	2
Choline	1	2
Daidzein	2	2
Deguelin	1	2
Emodin	1	2
Genistein	2	2
Ginseng	1	2
Green Coffee Bean	1	2
Green Tea	2	2
Guduchi	1	2
Licorice	1	2
Luteolin	2	2
Lycopene	1	2
Myricetin	1	2
Olive	1	2
Oridonin	2	2
Panax Notoginseng	1	2
Perilla	1	2
Prunella vulgaris	1	2
Raisins	2	2
Tanshinone IIA	2	2
Thymol	1	2
Vitamin E: alpha tocopherol	1	2
Vitexins	1	2
Xanthones	1	2
Yarrow	1	2
Acorus calamus	1	1
Alpha Linolenic Acid	1	1
Apigenin	1	1
Apple	1	1
Arginine	1	1
Artichoke	1	1
Ashwagandha	1	1
Asiatic Acid	1	1
Avocado	1	1
Bee Venom	1	1
Bisdemethoxycurcumin	1	1
Bitter Apple	1	1
Blueberry	1	1
Caffeic acid phenethyl ester	1	1
Caffeoylquinic Acids	1	1
Cannabinoids	1	1
Capsaicin	1	1
Carotenoids	1	1
Catechin	1	1
Chamomile	1	1
Cherry: All Varieties	1	1
Chrysanthemum Morifolium	1	1
Cinnamaldehyde	1	1
Cranberry Proanthocyanidins	1	1
Crocetin	1	1
Cucumber	1	1
Cucurbitacin E	1	1
Cyanidin 3-glucoside	1	1
Dogwood	1	1
Echinacea	1	1
Eugenol	1	1
Ferulic acid	1	1
Fruit: All	1	1
Fucoidan	1	1
Ginger	1	1
Glutamine	1	1
Goji	1	1
Grape Seed Extract	1	1
Hawthorn	1	1
Hemp Seed	1	1
Honeysuckle	1	1
Hops	1	1
Legumes	1	1
Lentinan	1	1
Lutein	1	1
Mangiferin	1	1
Melatonin	1	1
Moringa oleifera	1	1
Motherwort	1	1
Nettle	1	1
Nobiletin	1	1
Noni	1	1
Paeoniflorin	1	1
Palash	1	1
Parthenolide	1	1
Passion Flower	1	1
Patchouli	1	1
Peony	1	1
Piceatannol	1	1
Piperine	1	1
Psyllium	1	1
Puerarin	1	1
Purple Carrots	1	1
Raspberry	1	1
Reishi Mushroom	1	1
Royal Jelly	1	1
Saw Palmetto	1	1
Sea buckthorn	1	1
Seaweed	1	1
Selenium	1	1
Shikonin	1	1
Skullcap: Chinese	1	1
Sophora Flavescens	1	1
Soybean: Black	1	1
Strawberry	1	1
Sulforaphane	1	1
Sumac	1	1
Thistle	1	1
Thyme	1	1
Thymoquinone	1	1
Turkey Tail Mushroom	1	1
Vegetables: All	1	1
Vitamin C	1	1
Vitex negundo	1	1
White Mulberry	1	1
Wogonin	1	1
Xanthohumol	1	1
Zeaxanthin	1	1

[+]

A mindfulness-based stress reduction program might have beneficial effects on early stages of wound healing.May 31, 2018

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Pubmed Data : J Behav Med. 2018 Jun ;41(3):385-397. Epub 2017 Nov 20. PMID: 29159589

Article Published Date : May 31, 2018

Study Type : Human Study

Additional Links

Diseases : Wound Healing

Therapeutic Actions : Mindfullness Training

Pharmacological Actions : Interleukin-8 downregulation

[+]

A single 20 min session of yogic breathing practice could reduce the levels of key pro-inflammatory biomarkers in saliva.Aug 17, 2016

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Pubmed Data : Dermatology. 2014 ;229(2):102-9. Epub 2014 Sep 6. PMID: 25228478

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Pubmed Data : Respir Med. 2008 Nov 14. PMID: 19010653

Article Published Date : Nov 14, 2008

Study Type : Human Study

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Substances : Quercetin

Diseases : Sarcoidosis

Pharmacological Actions : Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : J Ethnopharmacol. 2019 Nov 7:112325. Epub 2019 Nov 7. PMID: 31707049

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Pubmed Data : Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26658749

Article Published Date : Dec 10, 2015

Study Type : Human In Vitro

Additional Links

Substances : Citral

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Curcumin may offer a viable alternative for the prevention or control of HIV replication in the female genital tract.Dec 31, 2014

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Pubmed Data : Sci Rep. 2020 Jul 27 ;10(1):12528. Epub 2020 Jul 27. PMID: 32719431

Article Published Date : Jul 26, 2020

Study Type : Animal Study

Additional Links

Diseases : Allergic Rhinitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra.Oct 27, 2020

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Pubmed Data : Lab Anim Res. 2020 Oct 28 ;36(1):40. Epub 2020 Oct 28. PMID: 33292858

Article Published Date : Oct 27, 2020

Study Type : Animal Study

Additional Links

Substances : Lactobacillus paracasei, Licorice, Perilla

Diseases : Helicobacter Pylori Infection

Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-8 downregulation

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Antiviral activity of ginseng extract against respiratory syncytial virus infection.Jun 30, 2014

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Pubmed Data : Oncotarget. 2015 Oct 17. Epub 2015 Oct 17. PMID: 26506421

Article Published Date : Oct 16, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cardamonin

Diseases : Breast Cancer, Breast Cancer Stem Cells

Pharmacological Actions : Chemotherapeutic, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Drug Resistant Cancer Stem Cells

[+]

Celastrol alleviates chronic obstructive pulmonary disease by inhibiting cellular inflammation induced by cigarette smoke.Dec 31, 2017

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Pubmed Data : Mol Nutr Food Res. 2017 Oct ;61(10). Epub 2017 Aug 29. PMID: 28731213

Article Published Date : Sep 30, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Olive leaf extract

Diseases : Colitis, Gastrointestinal Inflammation, Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : Atherosclerosis. 2004 Jul;175(1):39-49. PMID: 15186945

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Pubmed Data : Eur J Nutr. 2016 Mar 7. Epub 2016 Mar 7. PMID: 26951205

Article Published Date : Mar 06, 2016

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Cardiovascular Diseases, Hypertension

Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Hypolipidemic, Interleukin-8 downregulation

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Polysaccharide derived from Inonotus obliquus inhibits lipopolysaccharide-induced acute endometritis.Dec 31, 2021

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Pubmed Data : Am J Transl Res. 2022 ;14(11):8332-8342. Epub 2022 Nov 15. PMID: 36505332

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Pubmed Data : Am J Chin Med. 2020 ;48(5):1121-1140. PMID: 32668966

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Yarrow

Diseases : Atopic Dermatitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

This is the first demonstration of the anti-inflammatory properties of CBD in an experimental model of allergic contact dermatitis.Apr 08, 2018

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Pubmed Data : Nutrients. 2020 Jun 18 ;12(6). Epub 2020 Jun 18. PMID: 32570937

Article Published Date : Jun 17, 2020

Study Type : Animal Study

Additional Links

Substances : Choline, Feverfew, Green Coffee Bean, Milk Thistle, Vitamin E: alpha tocopherol

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : Phytother Res. 2020 May 30. Epub 2020 May 30. PMID: 32472655

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Pubmed Data : Molecules. 2020 Sep 23 ;25(19). Epub 2020 Sep 23. PMID: 32977636

Article Published Date : Sep 22, 2020

Study Type : In Vitro Study

Additional Links

Substances : Carrot

Diseases : Breast Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor

Additional Keywords : Cancer Stem Cells

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A combination of LL-37 and polyphenols from cranberry and green tea acted in synergy to reduce the secretion of cytokines by an LPS-stimulated 3D co-culture model of oral mucosal cells.May 31, 2015

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Pubmed Data : Arch Oral Biol. 2015 Jun ;60(6):845-53. Epub 2015 Feb 27. PMID: 25791329

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Pubmed Data : Int J Mol Sci. 2023 Feb 14 ;24(4). Epub 2023 Feb 14. PMID: 36835218

Article Published Date : Feb 13, 2023

Study Type : In Vitro Study

Additional Links

Substances : Allicin

Diseases : Lipopolysaccharide-Induced Toxicity, Mastitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Allicin could potentially alleviate oral cancer pain.May 22, 2021

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Pubmed Data : Phytother Res. 2020 Apr 6. Epub 2020 Apr 6. PMID: 32249518

Article Published Date : Apr 05, 2020

Study Type : Review

Additional Links

Substances : Carvacrol

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-8 downregulation, Malondialdehyde Down-regulation

[+]

Antioxidant and anti-Inflammatory effects of thyme essential oils.Jul 05, 2022

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Pubmed Data : Antioxidants (Basel). 2022 Jul 6 ;11(7). Epub 2022 Jul 6. PMID: 35883820

Article Published Date : Jul 05, 2022

Study Type : In Vitro Study

Additional Links

Substances : Thyme

Diseases : Lipopolysaccharide-Induced Toxicity, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Essential Oils

[+]

Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3.Dec 31, 2018

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Pubmed Data : J Cell Biochem. 2018 Nov 28. Epub 2018 Nov 28. PMID: 30485517

Article Published Date : Nov 27, 2018

Study Type : In Vitro Study

Additional Links

Substances : Carvacrol

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

CBD differentially regulated basal pro-inflammatory response and attenuated both LPS-induced cytokine release and NF-κB activity in monocytes.Aug 18, 2019

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Pubmed Data : Toxicol Appl Pharmacol. 2019 Aug 19:114713. Epub 2019 Aug 19. PMID: 31437494

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Pubmed Data : Cell Physiol Biochem. 2018 ;46(5):2072-2081. Epub 2018 Apr 28. PMID: 29723847

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Pubmed Data : Int Immunopharmacol. 2018 Sep ;62:86-95. Epub 2018 Jul 5. PMID: 29990698

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Melanoma

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Interleukin-8 downregulation, Postaglandin PGE2 downregulation

[+]

Ginger extract may be developed as a functional food for the maintenance of gastrointestinal health.Mar 28, 2017

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Pubmed Data : J Food Sci. 2017 Mar 29. Epub 2017 Mar 29. PMID: 28369951

Grape seed proanthocyanidin extract helps to prevent respiratory syncytial virus induced airway disease.Mar 31, 2019

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Pubmed Data : Mol Med Rep. 2019 Apr ;19(4):3330-3336. Epub 2019 Feb 19. PMID: 30816467

Article Published Date : Mar 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Grape Seed Extract

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation

[+]

Green and black tea extracts are capable of disrupting the molecular link between inflammation and carcinogenesis.Sep 30, 2010

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Pubmed Data : Planta Med. 2010 Oct ;76(15):1659-65. Epub 2010 May 26. PMID: 20506079

Article Published Date : Sep 30, 2010

Study Type : In Vitro Study

Additional Links

Substances : Black Tea, Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Gastric Cancer

Pharmacological Actions : Anticarcinogenic Agents, Interleukin-1 beta downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor

Additional Keywords : Plant Extracts

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Hyperoside attenuates inflammation in HT22 cells.Dec 31, 2020

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Pubmed Data : Int J Biol Macromol. 2020 Nov 18. Epub 2020 Nov 18. PMID: 33220376

Article Published Date : Nov 17, 2020

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Skin Diseases: Inflammatory

Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-1 beta downregulation, Interleukin-5 downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Luteolin as a modulator of skin aging and inflammation.Feb 28, 2021

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Pubmed Data : Open Dent J. 2018 ;12:265-274. Epub 2018 Mar 30. PMID: 29760819

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : White Mulberry

Diseases : Periodontal Diseases

Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation

Additional Keywords : Plant Extracts

[+]

Magnolol ameliorates the accumulation of reactive oxidative stress and inflammation in diabetic periodontitis.Feb 09, 2021

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2021 Nov 25 ;67(3):99-106. Epub 2021 Nov 25. PMID: 34933727

Article Published Date : Nov 24, 2021

Study Type : Review

Additional Links

Substances : Melatonin

Diseases : Alzheimer's Disease, Neurodegenerative Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Melatonin is an alternative therapeutic strategy to ameliorate poor condition for diabetic wound healing.Dec 31, 2015

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Pubmed Data : Molecules. 2022 Aug 4 ;27(15). Epub 2022 Aug 4. PMID: 35956908

Article Published Date : Aug 03, 2022

Study Type : In Vitro Study

Additional Links

Substances : Pomegranate

Diseases : Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Anti-Obesity Agents

[+]

Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19.Oct 15, 2020

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Pubmed Data : Inflammation. 2016 Jun ;39(3):1124-9. PMID: 27072015

Article Published Date : May 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Periodontal Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation, Interleukin-6 Downregulation, Interleukin-8 downregulation

[+]

Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways.Sep 13, 2021

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Pubmed Data : Sci Rep. 2021 Sep 14 ;11(1):18263. Epub 2021 Sep 14. PMID: 34521930

Article Published Date : Sep 13, 2021

Study Type : In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Sinensetin suppresses influenza a virus-triggered inflammation.May 04, 2020

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Pubmed Data : BMC Complement Med Ther. 2020 May 5 ;20(1):135. Epub 2020 May 5. PMID: 32370749

Article Published Date : May 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Inflammation, Influenza

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation,

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CoQ10 supplementation reduced some of the important markers of inflammation and MMPs in patients with breast cancer.May 31, 2021

A mindfulness-based stress reduction program might have beneficial effects on early stages of wound healing.May 31, 2018

A single 20 min session of yogic breathing practice could reduce the levels of key pro-inflammatory biomarkers in saliva.Aug 17, 2016

An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients. Jun 01, 2005

Anti-inflammatory effects of diet and caloric restriction in metabolic syndrome.Mar 07, 2021

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Coenzyme Q10 supplementation could be effective in ameliorating inflammatory cytokine levels caused by breast cancer.Dec 31, 2018

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

Curcumin could be used for improving nasal airflow and modulating immune response in patients with allergic rhinitis.Nov 30, 2016

Effect of berberine hydrochloride on the diversity of intestinal flora in Parkinson's disease patients.Dec 31, 2021

Effect of butylphthalide on serum CRP, PARK7, NT-3 and neurological function in patients with acute cerebral infarction.Dec 31, 2020

Effects of oligo-fucoidan on the immune response, inflammatory status and pulmonary function in patients with asthma.Oct 27, 2022

Effects of Pelargonium sidoides extract vs roxithromycin on chemokine levels in nasal secretions of patients with uncomplicated acute rhinosinusitis.Jan 31, 2021

Effects of standardized Brazilian green propolis extract on inflammation in haemodialysis patients.Dec 31, 2021

Fermented Carica papaya and Morinda citrifolia as perspective food supplements for the treatment of post-COVID symptoms.May 24, 2022

Fisetin could improve the inflammatory status in colorectal cancer patients.Mar 14, 2018

Ginkgo is effective in treating pulmonary interstitial fibrosis.Mar 01, 2005

Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19.Dec 31, 2020

L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.Feb 06, 2019

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation.Feb 16, 2021

Lactobacillus-fermented Chamaecyparis obtusa treatment was rapid and effective for treating acne lesions compared to tea tree oil.Dec 31, 2013

Mango polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase lactobacillus species in patients with inflammatory bowel disease. Dec 31, 2019

Micronized palmitoylethanolamide, hempseed oil, and maritime pine bark dry extract for pelvic pain.Feb 13, 2023

Oat porridge consumption alleviates markers of inflammation and oxidative stress in hypercholesterolemic adults.Dec 31, 2018

Omega-3 fatty acid supplementation reduces inflammatory biomarkers, erythrocyte sedimentation rate, and interleukin-8 concentrations in cystic fibrosis patients.May 01, 2010

Oral administration of tannase-treated green tea extract containing antioxidants without concomitant exercise can improve muscle mass and strength.Jun 24, 2021

Oral supplementation with pressurized whey improves nutritional status and can have additional beneficial effects on inflammation in patients with cystic fibrosis.Feb 01, 2010

Photobiomodulation improves serum cytokine response in mild to moderate COVID-19.Dec 31, 2021

Probiotic supplementation for 12 weeks in patients with multiple sclerosis significantly improved gene expression of IL-8 and TNF-α.Oct 31, 2017

Punicalagin might be one of natural therapeutic compounds for relieving rheumatoid arthritis progression.Dec 31, 2020

Quercetin significantly improves antioxidant status of patients with sarcoidosis.Nov 14, 2008

Role of ascorbic acid infusion in critically ill patients with transfusion-related acute lung injury.Dec 04, 2021

Salvia miltiorrhiza mitigates severe acute pancreatitis.Jan 01, 2007

Silibinin may improve the effects of methotrexate on certain biochemical and clinical markers of patients with active rheumatoid arthritis.Jun 30, 2016

Silymarin has anti-inflammatory activity superior to the drugs piroxicam and meloxicam in the treatment of osteoarthritis of the knee. Mar 10, 2010

Successful therapy of Clostridium difficile infection with fecal microbiota transplantation.Nov 30, 2016

The 3-year effect of the mediterranean diet intervention on inflammatory biomarkers related to cardiovascular disease.Jul 21, 2021

The effect of two-month treatment with Zataria multiflora on inflammatory cytokines, pulmonary function testes and respiratory symptoms in patients with chronic obstructive pulmonary disease.Jul 14, 2022

The present study provides evidence that Diabetea tea has hypoglycemic and antihyperlipidemic properties.Dec 23, 2016

The results concluded that inflammation as a major cause of hypertension was significantly decreased in patients using olive leaf extract tablets.Dec 31, 2018

These data strongly suggest that probiotics may down modulate key parameters of allergic rhinitis.Mar 31, 2011

This study contributes important insights into the potential benefits and mechanisms of tai chi.Aug 24, 2015

Vitamin D supplementation may contribute to reduced inflammation and improved lung function in cystic fibrosis.Dec 13, 2016

Z. multiflora reduced inflammation and improved pulmonary function tests indices in sulfur mustard-exposed patients.Nov 06, 2019

Zinc supplementation is associated with clinical and laboratory improvement in cases of neonatal respiratory distress syndrome.Dec 31, 2020

Antiviral and immunomodulatory effects of Pelargonium sidoides DC. root extract EPs® 7630 in SARS-CoV-2-infected human lung cells.Dec 31, 2020

Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.Dec 10, 2015

Curcumin may offer a viable alternative for the prevention or control of HIV replication in the female genital tract.Dec 31, 2014

Diosmetin exhibits anti-proliferative and anti-inflammatory effects on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.Dec 12, 2019

Neferine exerts a cytoprotective effect against hypoxia-induced oxidative stress and inflammation in human peripheral blood mononuclear cells.Jul 08, 2017

Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin.Sep 30, 2020

Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.May 31, 2015

Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.Mar 21, 2018

Rosmarinic acid may be a potential candidate for the treatment of psoriasis.Jun 14, 2016

Bromelain extract exerts antiarthritic effects via chondroprotection.Oct 22, 2021

Korean Red Ginseng water extract inhibits cadmium-induced lung injury.Aug 31, 2022

Terminalia chebula extract ameliorates the symptoms of atopic dermatitis.Jul 03, 2022

The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response.Jun 30, 2020

A combination of baicalin and berberine hydrochloride ameliorates dextran sulfate sodium-induced colitis.Jul 31, 2022

A frankincense nutraceutical inhibited tumor growth and induced apoptosis in vivo in breast cancer xenografts.Oct 01, 2019

Alantolactone suppresses proliferation and the inflammatory response in human HaCaT keratinocytes.Jun 24, 2021

Allicin can protect rats against myocardial ischemia reperfusion injury by suppressing inflammation and oxidative stress.Jul 31, 2019

Amelioration of PM 2.5-induced lung toxicity in rats by nutritional supplementation with biochanin A.Sep 30, 2020

An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo. Oct 12, 2015

Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling.Jul 26, 2020

Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra.Oct 27, 2020

Antiviral activity of ginseng extract against respiratory syncytial virus infection.Jun 30, 2014

Ar-turmerone exerts anti-proliferative and anti-inflammatory activities.Mar 31, 2020

Artemisia anomala herba alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions.Sep 05, 2021

Artificial tears containing epigallocatechin gallate and hyaluronic acid had a synergistic effect in the treatment of dry eye syndrome.Dec 31, 2015

Astragaloside IV improves high-fat diet-induced hepatic steatosis in nonalcoholic fatty liver disease.Dec 31, 2019

Interleukin-8 downregulation

View the Evidence:
332 Abstracts with Interleukin-8 downregulation Research