Laxative

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7 Substances Researched for Laxative
NameACCKFocus
Chicory110Locked
Kiwifruit110Locked
Prebiotics110Locked
Probiotics110Locked
Senna110Locked
Cascara sagrada12Locked
Parsley10Locked

View the Evidence:
37 Abstracts with Laxative Research

[+]

Bifidobacterium bifidum CCFM16 can potentially and efficaciously relieve chronic constipation in Chinese adults.Feb 06, 2022

Pubmed Data : Food Funct. 2022 Feb 7 ;13(3):1628-1640. Epub 2022 Feb 7. PMID: 35079761
Article Published Date : Feb 06, 2022
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Bifidum
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Both flaxseed and psyllium may decrease constipation symptoms, weight, glycemic and lipid levels, with flaxseed appearing to be superior to psyllium.Jan 31, 2019

Pubmed Data : Clin Nutr ESPEN. 2019 Feb ;29:41-48. Epub 2018 Nov 17. PMID: 30661699
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : Flaxseed, Psyllium
Diseases : Constipation, Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Laxative
Additional Keywords : Anti-Obesity Agents
[+]

Chicory-derived fermentable dietary fiber was effective in volunteers with chronic constipation and significantly improved bowel function.Aug 04, 2016

Pubmed Data : Int J Food Sci Nutr. 2016 Aug 5:1-8. Epub 2016 Aug 5. PMID: 27492975
Article Published Date : Aug 04, 2016
Study Type : Human Study
Additional Links
Substances : Chicory
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Compared to placebo, the use of P. oleracea in patients with functional constipation significantly improved CSBM, severity of symptoms, and quality of life.Feb 23, 2022

Pubmed Data : Saudi J Gastroenterol. 2022 Feb 24. Epub 2022 Feb 24. PMID: 35229757
Article Published Date : Feb 23, 2022
Study Type : Human Study
Additional Links
Substances : Purslane
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Comparison of the effects of abdominal massage and oral administration of sweet almond oil on constipation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:9661939. Epub 2022 Jun 21. PMID: 35774276
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Almond
Diseases : Constipation
Therapeutic Actions : Massage/Therapeutic Touch
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

consuming kefir daily could prevent constipation.Jun 30, 2018

Pubmed Data : Jpn J Nurs Sci. 2018 Jul ;15(3):218-225. Epub 2017 Nov 6. PMID: 29105976
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Kefir
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Daily use of olive oil or flaxseed oil was as effective as mineral oil in the treatment of constipation in patients undergoing hemodialysis.Dec 31, 2014

Pubmed Data : J Ren Nutr. 2015 Jan ;25(1):50-6. Epub 2014 Sep 17. PMID: 25238699
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Flaxseed, Olive Oil
Diseases : Constipation, Hemodialysis
Pharmacological Actions : Laxative
[+]

Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2020 ;29(1):61-67. PMID: 32229443
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients.Aug 31, 2010

Pubmed Data : J Clin Gastroenterol. 2010 Sep ;44 Suppl 1:S49-53. PMID: 20495470
Article Published Date : Aug 31, 2010
Study Type : Human Study
Additional Links
Substances : Artichoke, Lactobacillus paracasei
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Efficacy of newly developed kombucha-based specialized food product for treatment of constipation-predominant irritable bowel syndrome.Dec 31, 2021

Pubmed Data : Vopr Pitan. 2022 ;91(5):95-104. Epub 2022 Aug 30. PMID: 36394933
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Kombucha Tea
Diseases : Constipation, Irritable Bowel Syndrome
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Efficacy of the herbal formula of Foeniculum vulgare and Rosa damascena on elderly patients with functional constipation.Apr 30, 2022

Pubmed Data : J Integr Med. 2022 May ;20(3):230-236. Epub 2022 Mar 10. PMID: 35339396
Article Published Date : Apr 30, 2022
Study Type : Human Study
Additional Links
Substances : Fennel, Rose
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Evaluation of the anti-constipation effects of abdominal application of olive oil ointment in children 1-4 years old.Dec 31, 2020

Pubmed Data : Adv Exp Med Biol. 2021 ;1328:411-419. PMID: 34981493
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Flaxseed cookies used as a snack may be a useful tool for decreasing constipation symptoms, weight, glycemic and lipid levels in T2D patients. Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2018 ;15:36. Epub 2018 May 9. PMID: 29760761
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Constipation, Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Laxative
[+]

High-dose senna compares favorably with conventional polyethylene glycol-electrolyte lavage solution for outpatient colonoscopy preparation. Dec 01, 2005

Pubmed Data : Am J Gastroenterol. 2005 Dec;100(12):2674-80. PMID: 16393219
Article Published Date : Dec 01, 2005
Study Type : Human Study
Additional Links
Substances : Senna
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Intake of okara soup for 2 weeks for breakfast improved defecation habits in young Japanese women with self-reported constipation.Sep 30, 2020

Pubmed Data : J Food Sci. 2020 Oct ;85(10):3570-3576. Epub 2020 Sep 4. PMID: 32885419
Article Published Date : Sep 30, 2020
Study Type : Human Study
Additional Links
Substances : Soup
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Kiwifruit and kiwifruit-derived supplements demonstrated a clinically meaningful increase in bowel movements in healthy individuals.Apr 10, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res. 2015 Apr 11. Epub 2015 Apr 11. PMID: 25931419
Article Published Date : Apr 10, 2015
Study Type : Human Study
Additional Links
Substances : Kiwifruit
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Prune juice exerted an effective and safe natural food therapy for chronic constipation.Sep 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Gastroenterol. 2022 Oct 1 ;117(10):1714-1717. Epub 2022 Aug 12. PMID: 35971232
Article Published Date : Sep 30, 2022
Study Type : Human Study
Additional Links
Substances : Fiber, Polyphenols, Prune
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

The consumption of a fermented milk containing multiple probiotic strains and prebiotic fiber could improve constipation in patients with PD.Aug 18, 2016

Pubmed Data : Neurology. 2016 Aug 19. Epub 2016 Aug 19. PMID: 27543643
Article Published Date : Aug 18, 2016
Study Type : Human Study
Additional Links
Substances : Prebiotics, Probiotics
Diseases : Constipation, Parkinson's Disease
Pharmacological Actions : Laxative
[+]

The effect of abdominal massage on the severity of constipation in elderly patients hospitalized with fractures.Oct 31, 2022

Pubmed Data : Int J Orthop Trauma Nurs. 2022 Nov ;47:100936. Epub 2022 Feb 24. PMID: 36274468
Article Published Date : Oct 31, 2022
Study Type : Human Study
Additional Links
Diseases : Constipation
Therapeutic Actions : Massage/Therapeutic Touch
Pharmacological Actions : Laxative
[+]

The effect of abdominal massage with extra-virgin olive oil on constipation among elderly individuals.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Community Based Nurs Midwifery. 2021 Oct ;9(4):268-277. PMID: 34604396
Article Published Date : Sep 30, 2021
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

The effect of aroma massage on constipation in elderly individuals.Dec 31, 2022

Pubmed Data : Exp Gerontol. 2023 Jan ;171:112023. Epub 2022 Nov 11. PMID: 36372282
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : Constipation
Therapeutic Actions : Aromatherapy Massage
Pharmacological Actions : Laxative
[+]

Traditional Chinese medicine hemp seed pill could improve chronic constipation of elderly.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Family Med Prim Care. 2019 Jun ;8(6):2150. PMID: 31334198
Article Published Date : May 31, 2019
Study Type : Human: Case Report
Additional Links
Substances : Hemp Seed
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Amelioration effect of Lactobacillus plantarum KFY02 on low-fiber diet-induced constipation in mice by regulating gut microbiota.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:938869. Epub 2022 Aug 24. PMID: 36091233
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Anti-inflammatory response and muscarinic cholinergic regulation during the laxative effect of Asparagus cochinchinensis in loperamide-induced constipation.Feb 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Feb 21 ;20(4). Epub 2019 Feb 21. PMID: 30795644
Article Published Date : Feb 20, 2019
Study Type : Animal Study
Additional Links
Substances : Asparagus
Diseases : Constipation
Pharmacological Actions : Anti-Inflammatory Agents, Laxative
Additional Keywords : Plant Extracts
[+]

Black mulberry possesses prokinetic, laxative, and antidiarrheal effects.Jul 31, 2016

Pubmed Data : Phytother Res. 2016 Aug ;30(8):1362-76. Epub 2016 May 27. PMID: 27230535
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Mulberry
Diseases : Constipation, Diarrhea
Pharmacological Actions : Antidiarrheals, Laxative
[+]

Cascara sagrada does not contribute to carcinogenesis in a rat model, as does the stimulant laxative drug bisacodyl (Dulcolax). Sep 07, 2001

Pubmed Data : Life Sci. 2001 Sep 7;69(16):1871-7. PMID: 11693267
Article Published Date : Sep 07, 2001
Study Type : Animal Study
Additional Links
Substances : Cascara sagrada
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Ficus carica aqueous extract alleviates delayed gastric emptying and recovers ulcerative colitis-enhanced acute functional gastrointestinal disorders.Jun 01, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jun 2 ;224:242-249. Epub 2018 Jun 2. PMID: 29870788
Article Published Date : Jun 01, 2018
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Ulcerative Colitis
Pharmacological Actions : Antioxidants, Laxative
[+]

Flax seeds may serve as an effective diet supplement in the management of chronic constipation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Multidiscip Healthc. 2022 ;15:2407-2418. Epub 2022 Oct 20. PMID: 36299564
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Hesperidin improves colonic motility in loeramide-induced constipation.Aug 26, 2019

Pubmed Data : Digestion. 2019 Aug 27:1-14. Epub 2019 Aug 27. PMID: 31454820
Article Published Date : Aug 26, 2019
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Laxative effects of phlorotannins derived from Ecklonia cava on loperamide-induced constipation.Nov 27, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Nov 28 ;26(23). Epub 2021 Nov 28. PMID: 34885790
Article Published Date : Nov 27, 2021
Study Type : Animal Study
Additional Links
Substances : Phlorotannins, Seaweed: Brown
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents, Laxative
[+]

Laxative effects of triple fermented barley extracts on loperamide-induced constipation.Jun 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Jun 21 ;19(1):143. Epub 2019 Jun 21. PMID: 31226979
Article Published Date : Jun 20, 2019
Study Type : Animal Study
Additional Links
Substances : Barley, Fermented Foods and Beverages
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Plant Extracts
[+]

Naringenin may be effective as a candidate in patients suffering from lifestyle-induced constipation.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Feb ;41(2):649-658. Epub 2017 Dec 1. PMID: 29207043
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Opuntia humifusa water extract ameliorates loperamide-induced constipation in rats.Jan 16, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 17 ;17(1):49. Epub 2017 Jan 17. PMID: 28095842
Article Published Date : Jan 16, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Plant Extracts
[+]

These results demonstrate that probiotic chocolate has potential as a dietary adjunct for the treatment of constipation.Jan 31, 2019

Pubmed Data : Food Res Int. 2019 Feb ;116:1173-1182. Epub 2018 Oct 1. PMID: 30716903
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chocolate
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Nonfermented gel-forming psyllium was 3.4 times more effective than insoluble wheat bran for increasing stool output.Dec 31, 2019

Pubmed Data : J Am Assoc Nurse Pract. 2020 Jan ;32(1):15-23. PMID: 31764399
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Fiber, Psyllium
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Electron Physician. 2018 Feb ;10(2):6390-6399. Epub 2018 Feb 25. PMID: 29629064
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Substances : Plantago
Pharmacological Actions : Anti-Infective Agents, Anti-Inflammatory Agents, Anti-pyretic , Antitussive Agents, Astringents, Diuretics, Laxative
[+]

Parsley's traditional use as a laxative is supported by its inhibition of water absorption.Sep 01, 2001

Pubmed Data : Phytomedicine. 2001 Sep;8(5):382-8. PMID: 11695882
Article Published Date : Sep 01, 2001
Additional Links
Substances : Parsley
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Science Confirms Tradition

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