Matrix metalloproteinase-9 MMP-9 inhibitor

Name	AC	CK
Curcumin	28	39
Ginsenosides	24	39
Flavonoids	27	36
Resveratrol	13	34
Bee Propolis	4	23
Yoghurt	3	22
Berberine	12	18
Fisetin	7	16
Hesperidin	6	16
Pomegranate	6	16
Luteolin	10	15
Quercetin	10	15
Melatonin	11	14
EGCG (Epigallocatechin gallate)	3	13
Celery Oil	2	12
Coenzyme Q10	2	12
Genistein	2	12
Tanshinone IIA	8	12
Ellagic Acid	8	11
Mangosteen	2	11
Pycnogenol (Pine Bark)	2	11
Baicalein	8	10
Cannabinoids	1	10
Cannabis	1	10
Ginkgo biloba	8	10
Green Tea	6	10
Maqui	1	10
Naringenin	8	10
Polyphenols	7	10
Purslane	1	10
Vitamin D	1	10
Paeoniflorin	7	9
Sulforaphane	7	9
Thymoquinone	8	9
Turmeric	7	9
Aloe Vera	5	8
Mangiferin	6	8
Red Sage	4	8
Shikonin	3	8
Anthocyanins	6	7
Fucoidan	5	7
Gallic Acid	7	7
Grape	5	7
Parthenolide	2	7
Piperine	3	7
Vitamin C	4	7
Arctigenin	5	6
Black Tea	4	6
Chrysanthemum Indicum	2	6
EPA (Eicosapentaenoic Acid)	3	6
Formononetin	5	6
Garlic	4	6
Ginseng	2	6
Nobiletin	5	6
Rosmarinic acid	5	6
Safflower	5	6
Salvia miltiorrhiza	3	6
Wogonin	6	6
Apigenin	4	5
Beta-Elemene	5	5
Catechin	3	5
Cordyceps Militaris	4	5
Cucurbitacin B	5	5
Feverfew	1	5
Ginger	4	5
Isoliquiritigenin	3	5
Isothiocyanates	5	5
Licorice	4	5
Magnolol	4	5
Rice Bran	3	5
Seaweed: Brown	5	5
Ursolic Acid	4	5
Verbascoside	3	5
Zerumbone	4	5
Biochanin A	3	4
Celastrol	4	4
Chrysin	3	4
Crocin	3	4
Diosgenin	3	4
Fermented Foods and Beverages	2	4
Ginseng (Korean)	3	4
Grape Seed Extract	2	4
Hydrogen Water	2	4
Icariin	3	4
Isoflavones	2	4
Kaempferol	3	4
Myricetin	3	4
Neem	3	4
Omega-3 Fatty Acids	2	4
Oridonin	4	4
Persimmon	4	4
Phellinus Linteus	3	4
Phlorotannins	4	4
Probiotics	2	4
Punicalagin	4	4
Rose	3	4
Sesamol	2	4
Silibinin	3	4
Theaflavins	3	4
Tomatidine	3	4
Allicin	2	3
Artesunate	3	3
Astaxanthin	2	3
Bee Venom	3	3
Benzyl isothiocyanate	3	3
Berbamine	2	3
Beta Sitosterol	1	3
Bisdemethoxycurcumin	3	3
Bitter Melon	2	3
Cannabinoids: Synthetic	2	3
Carnosine	2	3
Carvacrol	2	3
Chaga Mushroom (Inonotus obliquus)	2	3
Citrus Triterpenoids	1	3
Citrus naringin	2	3
Crocetin	3	3
Deguelin	3	3
Echinacea	2	3
Elm tree	2	3
Emodin	2	3
Guduchi	2	3
Huaier (Trametes robiniophila murr)	3	3
Lignans	2	3
Ligustrazine	2	3
Lotus	3	3
Mulberry	2	3
NAC (N-acetyl-L-cysteine)	2	3
Organosulfur Compounds	2	3
Paeonol	2	3
Phloretin	3	3
Piceatannol	3	3
Pterostilbene	3	3
Reishi Mushroom	3	3
Rhubarb	3	3
Sinomenine	3	3
Tomato	2	3
Vanillin	1	3
Xanthohumol	3	3
Acai	1	2
Apple	1	2
Apple Polyphenols	2	2
Ashwagandha	2	2
Asiatic Acid	1	2
Astragaloside	2	2
Bamboo	1	2
Berries: All	1	2
Bifidobacterium Bifidum	1	2
Black Pepper	1	2
Boswellia	1	2
Bufalin	2	2
Burdock	2	2
Caffeic acid phenethyl ester	1	2
Cannabidiol	1	2
Carnosol	1	2
Curcumol	2	2
Cysteine (see N-Acetylcysteine)	1	2
D-Limonene	1	2
DHA (Docosahexaenoic Acid)	1	2
Diosmin	1	2
Dogwood	1	2
Eggplant	2	2
Elecampane	2	2
Fenugreek	2	2
Fig	1	2
Folic Acid	1	2
Frankincense	2	2
Genipin	1	2
Geraniol	1	2
Gleditsia sinensis	1	2
Hibiscus sabdariffa	1	2
Holy Basil	2	2
Hops	2	2
Kaempferia parviflora	1	2
Lactobacillus plantarum	1	2
Lavender	1	2
Leonurine	1	2
Lettuce	1	2
Liquiritigenin	1	2
Long Pepper	1	2
Loquat Leaves	2	2
Lycopene	1	2
Lysine	1	2
Manuka Honey	2	2
Medicinal Mushrooms	2	2
Noni	1	2
Oleanolic acid	1	2
Oolong tea	1	2
Palmitoylethanolamide	1	2
Panax Notoginseng	2	2
Panaxadiol	1	2
Phyllanthus amarus	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Phyllanthus urinaria	2	2
Pine Bark Extract	2	2
Pineapple	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Poria cocos	2	2
Proline	1	2
Propolis: Bee	1	2
Prunella vulgaris	2	2
Psychedelics:All	2	2
Red Marine Algae	1	2
Rosemaric Acid	2	2
Saffron	1	2
Saikosaponin	2	2
Schisandra	2	2
Sea Cucumber	1	2
Sea buckthorn	1	2
Sesame Seeds	2	2
St. Johns Wort	2	2
Stilbenes	2	2
Syringic Acid	1	2
Tamarind	1	2
Terminalia chebula	2	2
Tetrahydrocurcumin	1	2
Theanine	1	2
Thuja	1	2
Tocotrienol: Delta	2	2
Tocotrienol: Gamma	1	2
Toona sinensis	2	2
Triptolide	1	2
Vanillic Acid	1	2
Velvet antler	1	2
Vinegar	1	2
Vitamin E	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitamin E: alpha tocopherol	1	2
Vitamin K	1	2
Walnut	1	2
beta-Carotene	1	2
strawbrries	1	2
6-Shogaol	1	1
Achillea fragrantissima	1	1
Agaricus Blazei	1	1
Andrographis	1	1
Andrographolide	1	1
Antrodia camphorata	1	1
Bergamot	1	1
Beta-Caryophyllene	1	1
Betulinic acid	1	1
Black Raspberry	1	1
Blackberry	1	1
Blueberry	1	1
Bromelain	1	1
Capsaicin	1	1
Cardamonin	1	1
Chili pepper	1	1
Chlorogenic Acid	1	1
Cinnamaldehyde	1	1
Cinnamon	1	1
Citrus Peel	1	1
Curcuma phaeocaulis	1	1
Cyanidin 3-glucoside	1	1
Dandelion	1	1
Enterolactone	1	1
Eugenol	1	1
False Black Pepper	1	1
Ferulic acid	1	1
Fruit: All	1	1
Gac	1	1
Garcinia Mangostana	1	1
Germanium	1	1
Geum japonicum	1	1
Ginseng (Siberian)	1	1
Glycyrrhizin	1	1
Goji	1	1
Gold (nanoparticles)	1	1
Grapefruit	1	1
Guggul	1	1
Gynostemma	1	1
Harmine	1	1
Hawthorn	1	1
Herb Bennet	1	1
Honeybush	1	1
Honokiol	1	1
Horse Chestnut	1	1
Hydrangea	1	1
Hydroxytyrosol	1	1
Isothiocyanate	1	1
Jujube	1	1
Juniper	1	1
Justicia gendarussa	1	1
Lemon Peel	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Lupeol	1	1
Lychee	1	1
Magnolia	1	1
Marjoram	1	1
Milk Thistle	1	1
Nettle	1	1
Nisin	1	1
Oak	1	1
Oleuropein	1	1
Olive leaf extract	1	1
Orange: Mandarin	1	1
Oyster Mushroom	1	1
Pachymic acid	1	1
Palash	1	1
Papain	1	1
Passion Flower	1	1
Patchouli	1	1
Peach	1	1
Perilla	1	1
Phenethyl isothiocyanate	1	1
Piperlongumine	1	1
Plantago	1	1
Pomegranate Peel	1	1
Puerarin	1	1
Red Clover	1	1
Rice: Black	1	1
Rutin	1	1
Sage	1	1
Sesamin	1	1
Soursop	1	1
Syrian rue	1	1
Tangeretin	1	1
Thistle	1	1
Thymol	1	1
Turkey Tail Mushroom	1	1
Turmerones	1	1
Tyrosol	1	1
Urolithin A	1	1
Vegetables: All	1	1
Vitex negundo	1	1
Water: Deep Sea	1	1
Water: Deuterium Depleted	1	1
Wheat Grass	1	1
White Mulberry	1	1
Wormwood	1	1

[+]

A vegetarian diet is associated with a healthier profile of cardiovascular biomarkers compared to omnivorous.Aug 01, 2016

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Pubmed Data : Clin Chim Acta. 2016 Aug 2 ;461:110-113. Epub 2016 Aug 2. PMID: 27496081

Article Published Date : Aug 01, 2016

Study Type : Human Study

Additional Links

Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases

Therapeutic Actions : Dietary Modification: Vegetarian

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Risk Reduction

[+]

Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.Dec 04, 2016

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Pubmed Data : Sci Rep. 2016 Dec 5 ;6:37819. Epub 2016 Dec 5. PMID: 27917862

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Pubmed Data : Clin Neuropharmacol. 2016 Dec 9. Epub 2016 Dec 9. PMID: 27941526

Article Published Date : Dec 08, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Ischemia, Stroke: Attenuation/Recovery

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents

[+]

Fisetin prolongs therapy window of brain ischemic stroke using tissue plasminogen activator.Dec 31, 2018

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Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

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Pubmed Data : J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID: 27566200

Article Published Date : Dec 23, 2016

Study Type : Human In Vitro

Additional Links

Substances : Ginseng, Ginsenosides

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-metastatic, Chemosensitizer, Interleukin-6 Downregulation, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.Mar 31, 2017

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Acacetin alleviates inflammation and matrix degradation in nucleus pulposus cells and ameliorates intervertebral disc degeneration.Dec 31, 2019

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Pubmed Data : Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID: 29794468

Article Published Date : May 21, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Allicin

Diseases : Cholangiocarcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.Dec 31, 2012

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Pubmed Data : J Ethnopharmacol. 2016 Aug 22 ;190:142-58. Epub 2016 Jun 4. PMID: 27269390

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Pubmed Data : Prev Nutr Food Sci. 2022 Jun 30 ;27(2):172-179. PMID: 35919566

Article Published Date : Jun 29, 2022

Study Type : Animal Study

Additional Links

Substances : Rice Bran

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Anticancer effects of Gleditsia sinensis extract in rats transplanted with hepatocellular carcinoma cells.Aug 07, 2019

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Pubmed Data : Oncol Res. 2019 Aug 8 ;27(8):889-899. Epub 2019 Apr 2. PMID: 30940289

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Additional Keywords : Blood Brain Barrier

[+]

Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice.Nov 29, 2020

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Curcumin's antiulcer activity is primarily attributed to MMP-9 inhibition, one of the major path-ways of ulcer healing.Mar 11, 2005

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Pubmed Data : J Biol Chem. 2005 Mar 11;280(10):9409-15. Epub 2004 Dec 22. PMID: 15615723

Article Published Date : Mar 11, 2005

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Gastric Ulcer, Oxidative Stress

Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Drug: Indomethacin

[+]

D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis.Mar 31, 2017

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Early treatment of acute myocardial infarction with melatonin.Mar 29, 2022

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Additional Keywords : Natural Substance/Drug Synergy

[+]

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Pubmed Data : Int Immunopharmacol. 2017 Dec ;53:49-55. Epub 2017 Oct 15. PMID: 29035815

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Genipin

Diseases : Asthma

Pharmacological Actions : Anti-Asthmatic Agents, Cyclooxygenase 2 Inhibitors, interleukin-13 down-regulation, Interleukin-5 downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction.Jul 31, 2022

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Pubmed Data : J Biochem Mol Toxicol. 2022 Aug ;36(8):e23098. Epub 2022 May 24. PMID: 35608392

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Pubmed Data : Sci Rep. 2017 Dec 15 ;7(1):17670. Epub 2017 Dec 15. PMID: 29247225

Article Published Date : Dec 14, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Endometriosis

Pharmacological Actions : Anti-Fibrotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, MicroRNA modulator

[+]

Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer.Aug 31, 2014

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Pubmed Data : Drug Res (Stuttg). 2016 Jul ;66(7):339-44. Epub 2016 Apr 7. PMID: 27056637

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Pubmed Data : Environ Sci Pollut Res Int. 2022 Dec 22. Epub 2022 Dec 22. PMID: 36547838

Article Published Date : Dec 21, 2022

Study Type : Animal Study

Additional Links

Substances : Hesperidin

Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Renoprotective

[+]

Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.Dec 31, 2014

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Pubmed Data : Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID: 31004603

Article Published Date : Aug 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, MicroRNA modulator, Wnt/β-catenin signaling pathway modulation

[+]

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Pubmed Data : Nutr Cancer. 2015 ;67(5):761-70. Epub 2015 May 15. PMID: 25978595

Momordica charantia exosome-like nanoparticles exert neuroprotective effects against ischemic brain injury.Dec 31, 2021

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Pubmed Data : Front Pharmacol. 2022 ;13:908830. Epub 2022 Jun 24. PMID: 35814200

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Bitter Melon

Diseases : Cerebral Ischemia

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents

Additional Keywords : Exosomes

[+]

Morroniside protects against cerebral ischemia/reperfusion injury.Aug 31, 2018

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Pubmed Data : Pharm Biol. 2017 Dec ;55(1):423-427. PMID: 27937032

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Fatigue

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Naturally fermented Noni juice manifests a protective potential on liver fibrosis.Mar 31, 2017

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Pubmed Data : Food Funct. 2016 Jul 13 ;7(7):3121-9. PMID: 27279123

Article Published Date : Jul 12, 2016

Study Type : Animal Study

Additional Links

Substances : Nobiletin

Diseases : Cardiovascular Diseases, Diabetic Complications

Pharmacological Actions : Antioxidants, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Notoginsenoside R1 facilitated wound healing in high-fat diet/streptozotocin-induced diabetic rats.Dec 31, 2021

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Pubmed Data : Biosci Biotechnol Biochem. 2016 Apr 4:1-9. Epub 2016 Apr 4. PMID: 27045316

Article Published Date : Apr 03, 2016

Study Type : Animal Study

Additional Links

Substances : Aloe Vera

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Photoprotective

[+]

Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.Mar 31, 2012

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Preventive efficacy of vanillic acid on regulation of redox homeostasis, matrix metalloproteinases and cyclin D1 in rats bearing endometrial carcinoma.Sep 30, 2017

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Pubmed Data : Indian J Clin Biochem. 2017 Oct ;32(4):429-436. Epub 2016 Aug 24. PMID: 29062174

Article Published Date : Sep 30, 2017

Study Type : Animal Study

Additional Links

Substances : Vanillic Acid

Diseases : Endometrial Cancer

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Cyclin D1 Down-Regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Superoxide Dismutase Up-regulation

[+]

Pro-apoptotic, anti-metastatic, and anti-telomerase activity of Tinospora cordifolia and its active polysaccharide arabinogalactan during Benzo(a)pyrene-induced lung carcinogenesis.Apr 30, 2022

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Pubmed Data : Exp Ther Med. 2017 Dec ;14(6):6022-6026. Epub 2017 Oct 10. PMID: 29285153

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Quercetin reduces oxidative stress and inhibits activation of c Jun N terminal kinase/activator protein 1 signalling. Jan 31, 2014

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Pubmed Data : Prostate. 2019 Mar 19. Epub 2019 Mar 19. PMID: 30889629

Article Published Date : Mar 18, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Sea Cucumber

Diseases : Prostate Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights.Dec 31, 2017

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Pubmed Data : Redox Biol. 2018 06 ;16:169-178. Epub 2018 Mar 1. PMID: 29505920

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Pubmed Data : Cancer Prev Res (Phila). 2011 Jan ;4(1):65-75. Epub 2010 Nov 19. PMID: 21097714

Article Published Date : Dec 31, 2010

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabinoids: Synthetic

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Cannabinoid Receptors

[+]

These findings reveal a new potential therapeutic application of curcumin in anti-metastatic therapy for endometrial carcinoma.Aug 31, 2015

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Pubmed Data : Biomed Pharmacother. 2008 Jul-Aug;62(6):366-72. Epub 2007 Oct 22. PMID: 17988825

Article Published Date : Jul 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol, Stilbenes

Diseases : Cancer Metastasis, Liver Cancer

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Oncol Rep. 2014 Jan ;31(1):189-96. Epub 2013 Nov 20. PMID: 24270601

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Isothiocyanates

Diseases : Cancer Metastasis, Colorectal Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Aloin inhibits the proliferation and migration of gastric cancer cells.Dec 31, 2019

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Pubmed Data : Drug Des Devel Ther. 2020 ;14:145-155. Epub 2020 Jan 14. PMID: 32021099

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Aloe Vera

Diseases : Gastric Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

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Pubmed Data : Nutrients. 2023 Aug 16 ;15(16). Epub 2023 Aug 16. PMID: 37630786

Article Published Date : Aug 15, 2023

Study Type : In Vitro Study

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Substances : Gallic Acid

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

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Anticancer effects of Rosmarinus officinalis leaf extract on KB cell lines.Jan 31, 2024

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Pubmed Data : Cureus. 2024 Feb ;16(2):e54031. Epub 2024 Feb 11. PMID: 38481883

Article Published Date : Jan 31, 2024

Study Type : In Vitro Study

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Substances : Rosemaric Acid

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor

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Anticancer potential of naringenin, biosynthesis, molecular target, and structural perspectives.Sep 11, 2021

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Pubmed Data : Mini Rev Med Chem. 2021 Sep 12. Epub 2021 Sep 12. PMID: 34517796

Article Published Date : Sep 11, 2021

Study Type : In Vitro Study

Additional Links

Substances : Naringenin

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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View the Evidence: 720 Abstracts with Matrix metalloproteinase-9 (MMP-9) inhibitor Research

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A vegetarian diet is associated with a healthier profile of cardiovascular biomarkers compared to omnivorous.Aug 01, 2016

Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.Dec 04, 2016

Butylphthalide combined with conventional treatment attenuates MMP-9 levels and increases VEGF Levels in patients with stroke.Dec 31, 2020

Clinical and immunological efficacy of mangosteen and propolis extracted complex in patients with gingivitis.Jul 27, 2021

Combined light therapy shows promising results in patients with chronic meibomian gland dysfunction and dry eye disease, even in recalcitrant cases.Aug 31, 2022

CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.Apr 30, 2015

Effect of maqui-berry extract in dry eye disease - A clinical and molecular analysis.Mar 31, 2023

Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.Dec 08, 2016

Fisetin prolongs therapy window of brain ischemic stroke using tissue plasminogen activator.Dec 31, 2018

French maritime pine bark extract (Pycnogenol) displays anti-inflammatory effects in vivo.Jan 01, 2006

Hesperidin reduces adverse symptomatic intracerebral hemorrhage.Sep 01, 2019

Pomegranate juice significantly modulates matrix metalloproteinases 2 and 9 and serum levels of inflammatory factors protecting against exercise induced oxidative injury.Jun 30, 2014

Regular consumption of vitamin D-fortified yogurt drink improved endothelial biomarkers in subjects with type 2 diabetesNov 23, 2011

Regular probiotic yoghurt consumption guarded against exhaustive exercise-inducing oxidative injury in young healthy females.Nov 30, 2018

Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.Mar 27, 2016

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.Jan 02, 2017

Slow-velocity eccentric-only resistance training improves symptoms of type 2 diabetic mellitus patients by regulating plasma MMP-2 and -9.Jul 18, 2024

The anti-inflammatory activity of Cannabis extracts on colon epithelial cells derives from a fraction of the extract that contains THCA.Dec 31, 2016

The clinical effect of a propolis and mangosteen extract complex in subjects with gingivitis.Sep 04, 2024

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.Mar 31, 2017

Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.Dec 31, 2014

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.Apr 10, 2017

Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoagingFeb 29, 2016

Glabridin inhibited the invasion of human liver cancer cells.May 31, 2014

Limonin inhibits angiogenesis and metastasis of human breast cancer cells.Oct 31, 2020

Liposomal β-sitosterol suppresses metastasis of CT26/luc colon carcinoma.Jun 06, 2022

Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells.Apr 30, 2005

Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.Dec 31, 2014

A blend of Tamarindus indica and Curcuma longa extracts alleviates osteoarthritic pain and joint inflammation.May 23, 2023

A low molecular-weight gel fraction of Aloe vera has the potential to alleviate alcohol-induced acute gastric lesions.Nov 30, 2017

A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.Mar 17, 2017

Acacetin alleviates inflammation and matrix degradation in nucleus pulposus cells and ameliorates intervertebral disc degeneration.Dec 31, 2019

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Acceleration of wound healing activity with syringic acid in streptozotocin induced diabetic rats.Sep 14, 2019

Acupoint electroacupuncture intervention can significantly alleviate the inflammatory reaction of adjuvant arthritis.Dec 13, 1901

Administration of N- acetylcysteine and genistein have an additive gastroprotective effect in indomethacin induced gastric injury.Jul 15, 2018

Allicin inhibits the proliferation and invasion in cholangiocarcinoma.May 21, 2018

An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.Dec 31, 2012

Analysis of the potential biological mechanisms of diosmin against renal fibrosis.May 12, 2023

Anthocyanins derived from Vitis coignetiae Pulliat contributes anti-cancer effects in Hep3B human hepatocellular carcinoma cells.Nov 19, 2020

Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L.Aug 21, 2016

Anti-inflammatory effects of anethole in lipopolysaccharide-induced acute lung injury.Dec 04, 2013

Anti-inflammatory effects of rhamnetin on bradykinin-induced matrix metalloproteinase-9 expression and cell migration in rat brain astrocytes.Jan 05, 2022

Anti-obesity effect of rice bran extract on high-fat diet-induced obese mice. Jun 29, 2022

Anticancer effects of Gleditsia sinensis extract in rats transplanted with hepatocellular carcinoma cells.Aug 07, 2019

Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve.Sep 30, 2019

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.Dec 31, 2018

Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.Nov 11, 2019

Application of curcumin can inhibit expression of MMP-9, CD40L, TNF-α and CRP to improve the permeability of coronary artery.Dec 31, 2014

Arctigenin attenuates tumor metastasis of hepatocellular carcinoma.Dec 31, 2018

Ascorbic acid may be considered as a useful candidate to reduce the side effects of delayed application of ecombinant tissue plasminogen activators in stroke therapy.Apr 20, 2015

Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage.Oct 21, 2015

Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin.Mar 14, 2021

Baicalein alleviated myocardial remodelling and improved cardiac function.Jan 14, 2016

Berberine as a promising natural compound for the treatment of periodontal disease.Oct 29, 2021

Berberine attenuates experimental autoimmune encephalomyelitis in mice.Jan 01, 2010

Berberine protects against chronic cerebral hypoperfusion-induced cognitive impairment and hippocampal damage.Jun 09, 2022

Biomechanical and biochemical protective effect of low-level laser therapy for Achilles tendinitis.Dec 31, 2013

Black tea preserves intestinal homeostasis through balancing barriers and microbiota in mice.Dec 31, 2023

Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.Jan 17, 2017

Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model). Jan 01, 2011

Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.May 14, 2016

Camellia sinensis L. alleviates OVA-induced allergic asthma through NF-κB and MMP-9 pathways.Dec 31, 2023

Cardioprotective effect of Ulmus wallichiana in β-adrenergic agonist induced cardiac hypertrophy.Dec 31, 2015

Carnosine protects against cerebral ischemic injury by inhibiting matrix-metalloproteinases.Jul 12, 2021

Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.Dec 31, 2018

Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats.Feb 28, 2019

Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury.Sep 03, 2023

Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice.Nov 29, 2020

CBD can be used as a novel therapeutic option to inhibit growth and metastasis of highly aggressive breast cancer subtypes including TNBC.Mar 31, 2015

Matrix metalloproteinase-9 (MMP-9) inhibitor

View the Evidence:
720 Abstracts with Matrix metalloproteinase-9 (MMP-9) inhibitor Research