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Matrix metalloproteinase-9 (MMP-9) inhibitor
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267 Substances Researched for Matrix metalloproteinase-9 (MMP-9) inhibitor
Name
AC
CK
Focus
Curcumin
26
37
Ginsenosides
17
29
Resveratrol
10
22
Yoghurt
3
22
Pomegranate
5
15
Fisetin
5
14
EGCG (Epigallocatechin gallate)
3
13
Hesperidin
4
13
Quercetin
9
13
Coenzyme Q10
2
12
Genistein
2
12
Melatonin
10
12
Berberine
8
11
Flavonoids
9
11
Pycnogenol (Pine Bark)
2
11
Baicalein
8
10
Cannabinoids
1
10
Cannabis
1
10
Luteolin
7
10
Polyphenols
7
10
Purslane
1
10
Vitamin D
1
10
Naringenin
7
9
Paeoniflorin
7
9
Tanshinone IIA
6
9
Aloe Vera
5
8
Red Sage
4
8
Sulforaphane
6
8
Anthocyanins
6
7
Fucoidan
5
7
Grape
5
7
Parthenolide
2
7
Vitamin C
4
7
Arctigenin
5
6
Chrysanthemum Indicum
2
6
EPA (Eicosapentaenoic Acid)
3
6
Ellagic Acid
4
6
Formononetin
5
6
Ginseng
2
6
Green Tea
4
6
Piperine
2
6
Safflower
5
6
Apigenin
4
5
Feverfew
1
5
Ginger
4
5
Isoliquiritigenin
3
5
Isothiocyanates
5
5
Licorice
4
5
Nobiletin
4
5
Shikonin
1
5
Thymoquinone
5
5
Verbascoside
3
5
Wogonin
5
5
Black Tea
3
4
Chrysin
3
4
Cucurbitacin B
4
4
Ginseng (Korean)
3
4
Magnolol
3
4
Mangiferin
3
4
Omega-3 Fatty Acids
2
4
Oridonin
4
4
Phellinus Linteus
3
4
Rose
3
4
Sesamol
2
4
Theaflavins
3
4
Zerumbone
3
4
Allicin
2
3
Bee Propolis
2
3
Benzyl isothiocyanate
3
3
Biochanin A
2
3
Cannabinoids: Synthetic
2
3
Catechin
2
3
Celastrol
3
3
Chaga Mushroom (Inonotus obliquus)
2
3
Cordyceps Militaris
2
3
Deguelin
3
3
Emodin
2
3
Huaier (Trametes robiniophila murr)
3
3
Ligustrazine
2
3
Lotus
3
3
Mulberry
2
3
Myricetin
2
3
NAC (N-acetyl-L-cysteine)
2
3
Paeonol
2
3
Phloretin
3
3
Punicalagin
3
3
Rhubarb
3
3
Rice Bran
2
3
Tomato
2
3
Turmeric
3
3
Ursolic Acid
2
3
Acai
1
2
Apple
1
2
Apple Polyphenols
2
2
Ashwagandha
2
2
Asiatic Acid
1
2
Astaxanthin
1
2
Astragaloside
2
2
Bamboo
1
2
Bee Venom
2
2
Berries: All
1
2
Beta-Elemene
2
2
Bisdemethoxycurcumin
2
2
Black Pepper
1
2
Boswellia
1
2
Bufalin
2
2
Burdock
2
2
Caffeic acid phenethyl ester
1
2
Cannabidiol
1
2
Carnosol
1
2
Citrus naringin
1
2
Curcumol
2
2
Cysteine (see N-Acetylcysteine)
1
2
D-Limonene
1
2
DHA (Docosahexaenoic Acid)
1
2
Eggplant
2
2
Fermented Foods and Beverages
1
2
Fig
1
2
Folic Acid
1
2
Frankincense
2
2
Gallic Acid
2
2
Genipin
1
2
Ginkgo biloba
1
2
Gleditsia sinensis
1
2
Grape Seed Extract
1
2
Hibiscus sabdariffa
1
2
Holy Basil
2
2
Hydrogen Water
1
2
Kaempferia parviflora
1
2
Kaempferol
1
2
Lavender
1
2
Liquiritigenin
1
2
Long Pepper
1
2
Loquat Leaves
2
2
Lycopene
1
2
Lysine
1
2
Manuka Honey
2
2
Medicinal Mushrooms
2
2
Noni
1
2
Oleanolic acid
1
2
Oolong tea
1
2
Palmitoylethanolamide
1
2
Persimmon
2
2
Phyllanthus amarus
2
2
Phyllanthus niruri (Stonebreaker)
2
2
Phyllanthus urinaria
2
2
Piceatannol
2
2
Pine Bark Extract
2
2
Pineapple
1
2
Polyunsaturated Fatty Acids (PUFAs)
1
2
Poria cocos
2
2
Probiotics
1
2
Proline
1
2
Propolis: Bee
1
2
Prunella vulgaris
2
2
Psychedelics:All
2
2
Pterostilbene
2
2
Red Marine Algae
1
2
Reishi Mushroom
2
2
Rosmarinic acid
2
2
Saffron
1
2
Salvia miltiorrhiza
1
2
Schisandra
2
2
Sea Cucumber
1
2
Sea buckthorn
1
2
Silibinin
2
2
Stilbenes
2
2
Terminalia chebula
2
2
Thuja
1
2
Tocotrienol: Delta
2
2
Tocotrienol: Gamma
1
2
Tomatidine
2
2
Toona sinensis
2
2
Triptolide
1
2
Vinegar
1
2
Vitamin E
1
2
Vitamin E: Gamma-tocotrienol
1
2
Vitamin E: alpha tocopherol
1
2
Vitamin K
1
2
beta-Carotene
1
2
6-Shogaol
1
1
Achillea fragrantissima
1
1
Agaricus Blazei
1
1
Antrodia camphorata
1
1
Artesunate
1
1
Betulinic acid
1
1
Blackberry
1
1
Blueberry
1
1
Bromelain
1
1
Capsaicin
1
1
Carnosine
1
1
Carvacrol
1
1
Chili pepper
1
1
Citrus Peel
1
1
Crocetin
1
1
Crocin
1
1
Cyanidin 3-glucoside
1
1
Diosgenin
1
1
Enterolactone
1
1
False Black Pepper
1
1
Ferulic acid
1
1
Fruit: All
1
1
Gac
1
1
Garcinia Mangostana
1
1
Garlic
1
1
Germanium
1
1
Ginseng (Siberian)
1
1
Goji
1
1
Guduchi
1
1
Guggul
1
1
Gynostemma
1
1
Honeybush
1
1
Honokiol
1
1
Hops
1
1
Horse Chestnut
1
1
Hydrangea
1
1
Hydroxytyrosol
1
1
Jujube
1
1
Juniper
1
1
Justicia gendarussa
1
1
Lemon Peel
1
1
Lignans
1
1
Lion's Mane (Hericium Erinaceus)
1
1
Lupeol
1
1
Lychee
1
1
Magnolia
1
1
Mangosteen
1
1
Marjoram
1
1
Milk Thistle
1
1
Neem
1
1
Nettle
1
1
Oak
1
1
Oleuropein
1
1
Olive leaf extract
1
1
Orange: Mandarin
1
1
Pachymic acid
1
1
Palash
1
1
Panax Notoginseng
1
1
Papain
1
1
Passion Flower
1
1
Peach
1
1
Phenethyl isothiocyanate
1
1
Piperlongumine
1
1
Pomegranate Peel
1
1
Puerarin
1
1
Red Clover
1
1
Rice: Black
1
1
Rosemaric Acid
1
1
Rutin
1
1
Sesame Seeds
1
1
Sesamin
1
1
Soursop
1
1
St. Johns Wort
1
1
Syrian rue
1
1
Thistle
1
1
Thymol
1
1
Turkey Tail Mushroom
1
1
Turmerones
1
1
Tyrosol
1
1
Vegetables: All
1
1
Vitex negundo
1
1
Water: Deep Sea
1
1
Water: Deuterium Depleted
1
1
Wheat Grass
1
1
White Mulberry
1
1
Wormwood
1
1
Xanthohumol
1
1
Research Articles
505
Cumulative Knowledge Score
817
Overall Research Rating
EXCELLENT
View the Evidence:
657 Abstracts with Matrix metalloproteinase-9 (MMP-9) inhibitor Research
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[+]
A vegetarian diet is associated with a healthier profile of cardiovascular biomarkers compared to omnivorous.
Aug 01, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Chim Acta. 2016 Aug 2 ;461:110-113. Epub 2016 Aug 2. PMID:
27496081
Article Published Date
: Aug 01, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Risk Reduction
[+]
Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.
Dec 04, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Dec 5 ;6:37819. Epub 2016 Dec 5. PMID:
27917862
Article Published Date
: Dec 04, 2016
Study Type
: Human Study
Additional Links
Substances
:
Purslane
Diseases
:
Atherosclerosis
,
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
NF-kappaB Inhibitor
,
Uricosuric Agents
Additional Keywords
:
Risk Reduction
[+]
Butylphthalide combined with conventional treatment attenuates MMP-9 levels and increases VEGF Levels in patients with stroke.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Neurol. 2021 ;12:686199. Epub 2021 Dec 20. PMID:
34987460
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Celery Oil
Diseases
:
Stroke
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Clinical and immunological efficacy of mangosteen and propolis extracted complex in patients with gingivitis.
Jul 27, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Jul 28 ;13(8). Epub 2021 Jul 28. PMID:
34444764
Article Published Date
: Jul 27, 2021
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2015 May ;18(4):169-76. Epub 2014 Jan 10. PMID:
24621064
Article Published Date
: Apr 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effect of maqui-berry extract in dry eye disease - A clinical and molecular analysis.
Mar 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Indian J Ophthalmol. 2023 Apr ;71(4):1613-1618. PMID:
37026311
Article Published Date
: Mar 31, 2023
Study Type
: Human Study
Additional Links
Substances
:
Maqui
Diseases
:
Dry Eye Syndromes
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.
Dec 08, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Neuropharmacol. 2016 Dec 9. Epub 2016 Dec 9. PMID:
27941526
Article Published Date
: Dec 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Ischemia
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Fisetin prolongs therapy window of brain ischemic stroke using tissue plasminogen activator.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619871359. PMID:
31434498
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Fisetin
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
French maritime pine bark extract (Pycnogenol) displays anti-inflammatory effects in vivo.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Inflamm (Lond). 2006;3:1. Epub 2006 Jan 27. PMID:
16441890
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Inflammation
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Hesperidin reduces adverse symptomatic intracerebral hemorrhage.
Sep 01, 2019
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2019 Sep 2. Epub 2019 Sep 2. PMID:
31478148
Article Published Date
: Sep 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Cerebral Hemorrhage
,
Stroke: Ischemic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Pomegranate juice significantly modulates matrix metalloproteinases 2 and 9 and serum levels of inflammatory factors protecting against exercise induced oxidative injury.
Jun 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2014 Jul ;64(7):785-90. PMID:
25255587
Article Published Date
: Jun 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Prolonged Exercise
[+]
Regular consumption of vitamin D-fortified yogurt drink improved endothelial biomarkers in subjects with type 2 diabetes
Nov 23, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Med. 2011 Nov 24 ;9:125. Epub 2011 Nov 24. PMID:
22114787
Article Published Date
: Nov 23, 2011
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
,
Yoghurt
Diseases
:
Diabetes Mellitus: Type 2
,
Hypertension
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Regular probiotic yoghurt consumption guarded against exhaustive exercise-inducing oxidative injury in young healthy females.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2018 Dec ;68(12):1748-1754. PMID:
30504936
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.
Mar 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Mar 28. Epub 2016 Mar 28. PMID:
27035424
Article Published Date
: Mar 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Resveratrol
Diseases
:
Chronic Obstructive Pulmonary Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.
Jan 02, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2017 01 3 ;14(1):1. Epub 2017 Jan 3. PMID:
28086917
Article Published Date
: Jan 02, 2017
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
The anti-inflammatory activity of Cannabis extracts on colon epithelial cells derives from a fraction of the extract that contains THCA.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2017 ;2(1):167-182. Epub 2017 Jul 1. PMID:
29082314
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intest Res. 2017 Apr ;15(2):174-181. Epub 2017 Apr 27. PMID:
28522946
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Feverfew
,
Parthenolide
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Jan ;24(1):50-8. Epub 2014 Nov 20. PMID:
25479727
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Piperine
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.
Apr 10, 2017
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2017 Apr 11. Epub 2017 Apr 11. PMID:
28401486
Article Published Date
: Apr 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Shikonin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic Synergy: Temozolomide
,
Glioblastoma
,
Shikonin
[+]
Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoaging
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cytotechnology. 2016 Mar ;68(2):229-40. Epub 2014 Jul 23. PMID:
25052044
Article Published Date
: Feb 29, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Glabridin inhibited the invasion of human liver cancer cells.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2014 Jun ;171(12):3037-50. PMID:
24641665
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoflavones
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Liposomal β-sitosterol suppresses metastasis of CT26/luc colon carcinoma.
Jun 06, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceutics. 2022 Jun 7 ;14(6). Epub 2022 Jun 7. PMID:
35745788
Article Published Date
: Jun 06, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Beta Sitosterol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Immunomodulatory
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0123478. Epub 2015 May 8. PMID:
25954974
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
[+]
A blend of Tamarindus indica and Curcuma longa extracts alleviates osteoarthritic pain and joint inflammation.
May 23, 2023
Click here to read the entire abstract
Pubmed Data
: J Am Nutr Assoc. 2023 May 24:1-11. Epub 2023 May 24. PMID:
37224433
Article Published Date
: May 23, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Tamarind
,
Turmeric
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Chondroprotective
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A low molecular-weight gel fraction of Aloe vera has the potential to alleviate alcohol-induced acute gastric lesions.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):2110-2115. PMID:
28874080
Article Published Date
: Nov 30, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.
Mar 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 18 ;9(3). Epub 2017 Mar 18. PMID:
28335466
Article Published Date
: Mar 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Lysine
,
Proline
,
Quercetin
,
Vitamin C
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Acacetin alleviates inflammation and matrix degradation in nucleus pulposus cells and ameliorates intervertebral disc degeneration.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:4801-4813. Epub 2020 Nov 10. PMID:
33204066
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Degenerative Disk Disease
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2016 ;11(11):e0166059. Epub 2016 Aug 16. PMID:
27851787
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Acai
Diseases
:
Endometriosis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Nitric Oxide Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Acupoint electroacupuncture intervention can significantly alleviate the inflammatory reaction of adjuvant arthritis.
Dec 13, 1901
Click here to read the entire abstract
Pubmed Data
: Zhen Ci Yan Jiu. 2019 Sept 25;44(9):659-62. PMID:
31532135
Study Type
: Animal Study
Additional Links
Diseases
:
Arthritis
,
Inflammation
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Administration of N- acetylcysteine and genistein have an additive gastroprotective effect in indomethacin induced gastric injury.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2018 Jul 16. Epub 2018 Jul 16. PMID:
30011378
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Genistein
Diseases
:
Drug-Induced Toxicity: Indomethacin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Allicin inhibits the proliferation and invasion in cholangiocarcinoma.
May 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID:
29794468
Article Published Date
: May 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(10):e78061. Epub 2013 Oct 28. PMID:
24205091
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Analysis of the potential biological mechanisms of diosmin against renal fibrosis.
May 12, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2023 May 13 ;23(1):157. Epub 2023 May 13. PMID:
37179298
Article Published Date
: May 12, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Kidney Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Renoprotective
[+]
Anthocyanins derived from Vitis coignetiae Pulliat contributes anti-cancer effects in Hep3B human hepatocellular carcinoma cells.
Nov 19, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Nov 20 ;25(22). Epub 2020 Nov 20. PMID:
33233701
Article Published Date
: Nov 19, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L.
Aug 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Aug 22 ;190:142-58. Epub 2016 Jun 4. PMID:
27269390
Article Published Date
: Aug 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Lavender
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Inflammatory Bowel Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anti-obesity effect of rice bran extract on high-fat diet-induced obese mice.
Jun 29, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prev Nutr Food Sci. 2022 Jun 30 ;27(2):172-179. PMID:
35919566
Article Published Date
: Jun 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Rice Bran
Diseases
:
High Fat Diet
,
Obesity
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Anticancer effects of Gleditsia sinensis extract in rats transplanted with hepatocellular carcinoma cells.
Aug 07, 2019
Click here to read the entire abstract
Pubmed Data
: Oncol Res. 2019 Aug 8 ;27(8):889-899. Epub 2019 Apr 2. PMID:
30940289
Article Published Date
: Aug 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gleditsia sinensis
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Oct ;75:105753. Epub 2019 Jul 20. PMID:
31336334
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Sciatica
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antinoceceptive
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2019 Jun ;54(6):2069-2079. Epub 2019 Apr 16. PMID:
31081060
Article Published Date
: May 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2019 ;16:49. Epub 2019 Jul 26. PMID:
31372176
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pineapple
,
Vinegar
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.
Nov 11, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2019 Nov 12. Epub 2019 Nov 12. PMID:
31714653
Article Published Date
: Nov 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Magnolol
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Application of curcumin can inhibit expression of MMP-9, CD40L, TNF-α and CRP to improve the permeability of coronary artery.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Pathol. 2015 ;8(6):7247-53. Epub 2015 Jun 1. PMID:
26261622
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Atherosclerosis
,
C-Reactive Protein
,
Coronary Artery Disease
,
High Fat Diet
Pharmacological Actions
:
Cardiovascular Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Arctigenin attenuates tumor metastasis of hepatocellular carcinoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:937. Epub 2019 Aug 29. PMID:
31555129
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Ascorbic acid may be considered as a useful candidate to reduce the side effects of delayed application of ecombinant tissue plasminogen activators in stroke therapy.
Apr 20, 2015
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2015 Apr 21. Epub 2015 Apr 21. PMID:
25899606
Article Published Date
: Apr 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage.
Oct 21, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2015 Oct 22 ;1624:113-24. Epub 2015 Jul 23. PMID:
26210617
Article Published Date
: Oct 21, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Subarachnoid hemorrhage
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin.
Mar 14, 2021
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2021 Mar 15:1-12. Epub 2021 Mar 15. PMID:
33719799
Article Published Date
: Mar 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Hypolipidemic
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalein alleviated myocardial remodelling and improved cardiac function.
Jan 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jan 15 ;145:213-23. Epub 2015 Dec 17. PMID:
26706290
Article Published Date
: Jan 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberine as a promising natural compound for the treatment of periodontal disease.
Oct 29, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2021 Oct 30. Epub 2021 Oct 30. PMID:
34719112
Article Published Date
: Oct 29, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine attenuates experimental autoimmune encephalomyelitis in mice.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(10):e13489. Epub 2010 Oct 19. PMID:
20976070
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Blood-Brain-Barrier Disorders
,
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberine protects against chronic cerebral hypoperfusion-induced cognitive impairment and hippocampal damage.
Jun 09, 2022
Click here to read the entire abstract
Pubmed Data
: J Chem Neuroanat. 2022 Jun 10:102119. Epub 2022 Jun 10. PMID:
35697268
Article Published Date
: Jun 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Cerebral Hypoperfusion
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Nrf2 activation
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.
Jan 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2017 Jan 18. Epub 2017 Jan 18. PMID:
28098340
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
,
Fibrosarcoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model).
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID:
22066019
Article Published Date
: Jan 01, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Boswellia
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.
May 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 15. Epub 2016 May 15. PMID:
27191743
Article Published Date
: May 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bee Propolis
,
Caffeic acid phenethyl ester
Diseases
:
Cancer Metastasis
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Cardioprotective effect of Ulmus wallichiana in β-adrenergic agonist induced cardiac hypertrophy.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:510. Epub 2016 Dec 21. PMID:
28066255
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Elm tree
Diseases
:
Cardiac Hypertrophy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Carnosine protects against cerebral ischemic injury by inhibiting matrix-metalloproteinases.
Jul 12, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Jul 13 ;22(14). Epub 2021 Jul 13. PMID:
34299128
Article Published Date
: Jul 12, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Carnosine
Diseases
:
Brain Ischemia
,
Stroke
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2019 ;9:743. Epub 2019 Aug 8. PMID:
31456939
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carnosol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Anat. 2019 Mar ;222:120-128. Epub 2018 Dec 24. PMID:
30590121
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Safflower
Diseases
:
Hypertension
Pharmacological Actions
:
Cardioprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury.
Sep 03, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2023 Sep 4 ;13(1):14546. Epub 2023 Sep 4. PMID:
37666857
Article Published Date
: Sep 03, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Brain Injury: Traumatic
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice.
Nov 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chin Med. 2020 Nov 30 ;15(1):125. Epub 2020 Nov 30. PMID:
33292347
Article Published Date
: Nov 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Oolong tea
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
CBD can be used as a novel therapeutic option to inhibit growth and metastasis of highly aggressive breast cancer subtypes including TNBC.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Oncol. 2015 Apr ;9(4):906-19. Epub 2015 Jan 19. PMID:
25660577
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Epidermal growth factor receptor (EGFR) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction.
Sep 16, 2018
Click here to read the entire abstract
Pubmed Data
: J Mol Histol. 2018 Sep 17. Epub 2018 Sep 17. PMID:
30225683
Article Published Date
: Sep 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Fibrosis
,
Myocardial Infarction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Components of Salvia miltiorrhiza Bunge, could inhibit the development of elastase-induced experimental abdominal aortic aneurysms.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2012 Dec ;178(2):1029-37. Epub 2012 May 17. PMID:
22640888
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aneurysm: Aortic
,
Hypertension
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Dec ;16(6):6930-6939. Epub 2018 Sep 27. PMID:
30546425
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Crocin and Metformin suppress metastatic breast cancer progression.
Apr 29, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2021 Apr 30. Epub 2021 Apr 30. PMID:
33929675
Article Published Date
: Apr 29, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Crocin
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease.
Aug 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2023 Sep ;165:115105. Epub 2023 Jul 1. PMID:
37399718
Article Published Date
: Aug 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Chronic Obstructive Pulmonary Disease
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cryptotanshinone could be developed as a potential therapeutic agent for the treatment of chronic diabetic wound healing.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2020 Dec ;58(1):845-853. PMID:
32870741
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Diabetes Mellitus: Type 2
,
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Cucurbitacin B inhibited breast cancer metastasis and angiogenesis.
May 18, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Biochem Cell Biol. 2016 May 19 ;77(Pt A):41-56. Epub 2016 May 19. PMID:
27210504
Article Published Date
: May 18, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin alleviates matrix metalloproteinases associated with inflammation during eradication of H. pylori infection.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011;6(1):e16306. Epub 2011 Jan 21. PMID:
21283694
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin can significantly decrease cerebral ischemia reperfusions pathological damage and suppressed the expression of MMP-9 and TNF-α.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Zhong Yao Cai. 2015 Feb ;38(2):344-9. PMID:
26415414
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin could restore the core and associated symptoms of the autistic phenotype by suppressing oxidative-nitrosative stress, mitochondrial dysfunction in PPA-induced autism in rats.
Sep 22, 2015
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2015 Sep 23. Epub 2015 Sep 23. PMID:
26407474
Article Published Date
: Sep 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuromodulatory
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.
Sep 07, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Sep 7. Epub 2010 Sep 7. PMID:
20824699
Article Published Date
: Sep 07, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-Proliferative
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Curcumin inhibits the growth of choroidal melanoma.
Jan 15, 2011
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2011 Jan 15;11(2):229-35. Epub 2011 Jan 15. PMID:
21084858
Article Published Date
: Jan 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Melanoma
,
Melanoma: Choroidal
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin sensitizes human colorectal cancer to capecitabine.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2009 Nov 1 ;125(9):2187-97. PMID:
19623659
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Curcumin's antiulcer activity is primarily attributed to MMP-9 inhibition, one of the major path-ways of ulcer healing.
Mar 11, 2005
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2005 Mar 11;280(10):9409-15. Epub 2004 Dec 22. PMID:
15615723
Article Published Date
: Mar 11, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Gastric Ulcer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Drug: Indomethacin
[+]
D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2017 Apr ;15(4):2339-2346. Epub 2017 Feb 22. PMID:
28260017
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
D-Limonene
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Postaglandin PGE2 downregulation
[+]
Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.
Jul 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jul 5 ;758:188-96. Epub 2015 Apr 8. PMID:
25863259
Article Published Date
: Jul 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary intake of EPA and DHA prevented abdominal aortic aneurysm development.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Circ J. 2015 ;79(7):1470-8. Epub 2015 Apr 30. PMID:
25925976
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
EPA (Eicosapentaenoic Acid)
,
Omega-3 Fatty Acids
Diseases
:
Aneurysm: Aortic
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary supplementation with n-3 PUFAs may have protective anti-inflammatory effects mediated through modulation of MMPs and TIMPs.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Heart Lung Circ. 2015 Apr ;24(4):377-85. Epub 2014 Nov 20. PMID:
25512019
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Diosgenin could be a good candidate for new MS treatment strategies.
Sep 30, 2021
Click here to read the entire abstract
Pubmed Data
: Mult Scler Relat Disord. 2021 Oct ;55:103211. Epub 2021 Aug 10. PMID:
34425463
Article Published Date
: Sep 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dl-3-n-butylphthalide attenuates spinal cord injury.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2021 Sep ;46(9):2297-2306. Epub 2021 Jun 4. PMID:
34086144
Article Published Date
: Aug 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Celery Oil
Diseases
:
Hypoxia
,
Spinal Cord Injuries
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Early treatment of acute myocardial infarction with melatonin.
Mar 29, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Med. 2022 Mar 30 ;11(7). Epub 2022 Mar 30. PMID:
35407517
Article Published Date
: Mar 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effect of hyperbaric oxygen treatment in a rat model of abdominal aortic aneurysm.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Undersea Hyperb Med. 2014 Jan-Feb;41(1):9-15. PMID:
24649712
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Aneurysm: Aortic
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effect of photobiomodulation therapy on the proliferation phase and wound healing in rats fed with an experimental hypoproteic diet.
Nov 05, 2020
Click here to read the entire abstract
Pubmed Data
: Lasers Med Sci. 2020 Nov 6. Epub 2020 Nov 6. PMID:
33156476
Article Published Date
: Nov 05, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Wound Healing
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Cir Bras. 2021 ;36(9):e360904. Epub 2021 Nov 8. PMID:
34755764
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Silibinin
Diseases
:
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats.
Oct 31, 2020
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2020 Nov ;33(6):2527-2533. PMID:
33867326
Article Published Date
: Oct 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Shikonin
Diseases
:
High Fat Diet
,
Liver Fibrosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
EGCG inhibited SW780 bladder cancer tumor growth by down-regulation of NF-κB and MMP-9.
Dec 19, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Dec 20 ;41:56-64. Epub 2016 Dec 20. PMID:
28040581
Article Published Date
: Dec 19, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Ellagic acid may be beneficial for the treatment of glioblastoma.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb ;37(2):1084-1092. Epub 2016 Dec 22. PMID:
28035411
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Bcl-2 protein down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Emodin exerts anti-metastatic activity in pancreatic cancer both in vitro and in vivo.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID:
22375400
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID:
26919952
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
EPA prevents the development of abdominal aortic aneurysms.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(10):e0165132. Epub 2016 Oct 20. PMID:
27764222
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fermented lettuce extract containing nitric oxide metabolites attenuates inflammatory parameters.
Feb 22, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2023 Feb 23 ;15(5). Epub 2023 Feb 23. PMID:
36904105
Article Published Date
: Feb 22, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Lettuce
Diseases
:
Arthritis
,
Rheumatoid Arthritis
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine.
Apr 14, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2012 Apr 15 ;18(8):2220-9. Epub 2012 Feb 20. PMID:
22351692
Article Published Date
: Apr 14, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienol: Gamma
,
Vitamin E
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Bcl-2 protein down-regulation
,
Chemosensitizer
,
Cyclin D1 Down-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Folic acid modulates matrix metalloproteinase-9 expression following spinal cord injury.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Neurosci. 2019 Apr ;26(2):60-65. Epub 2019 Apr 1. PMID:
31975775
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Folic Acid
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fucoidan suppresses hypoxia-induced lymphangiogenesis and lymphatic metastasis in mouse hepatocarcinoma.
Jun 02, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2015 Jun 3 ;13(6):3514-30. Epub 2015 Jun 3. PMID:
26047481
Article Published Date
: Jun 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Hypoxia
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Genipin inhibits allergic responses in ovalbumin-induced asthmatic mice.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Dec ;53:49-55. Epub 2017 Oct 15. PMID:
29035815
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Genipin
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
,
Cyclooxygenase 2 Inhibitors
,
interleukin-13 down-regulation
,
Interleukin-5 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2022 Aug ;36(8):e23098. Epub 2022 May 24. PMID:
35608392
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Geraniol
Diseases
:
Inflammation
,
Lipid Peroxidation
,
Myocardial Infarction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Problem Substances
:
Isoproterenol
[+]
Ginsenoside compound K suppresses tumor growth in the 22Rv1 xenograft model.
Nov 07, 2022
Click here to read the entire abstract
Pubmed Data
: FEBS J. 2022 Nov 8. Epub 2022 Nov 8. PMID:
36349420
Article Published Date
: Nov 07, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg1 may represent a novel treatment target for spinal cord injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2017 ;40(10):1630-1637. PMID:
28966235
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 decreases fibrotic and invasive nature of endometriosis.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Dec 15 ;7(1):17670. Epub 2017 Dec 15. PMID:
29247225
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
[+]
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer.
Aug 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2014 Sep ;45(3):1065-72. Epub 2014 Jun 16. PMID:
24938458
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 inhibits migration and invasion, and promotes apoptosis of Caco-2 cells.
Jan 07, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2019 Jan 8 ;106:131-138. Epub 2019 Jan 8. PMID:
30633886
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 might be a useful agent for the treatment of metastatic thyroid cancers.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):849-857. Epub 2018 Aug 23. PMID:
30136914
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.
Jun 17, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Beijing Da Xue Xue Bao Yi Xue Ban. 2016 Jun 18 ;48(3):496-501. PMID:
27318914
Article Published Date
: Jun 17, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Grape juice concentrate protects rat liver against cadmium intoxication.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Res (Stuttg). 2016 Jul ;66(7):339-44. Epub 2016 Apr 7. PMID:
27056637
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cadmium
[+]
Grape juice has a hypolipidemic and cardiac protective potential.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2020 ;15(9):e0238163. Epub 2020 Sep 3. PMID:
32881885
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Dyslipidemias
Pharmacological Actions
:
Hypolipidemic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Grape seed extracts may improve the quality of life of lung fibrosis patients by inhibiting MMP-9 and TGF-β1 expression in the lungs.
Mar 11, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2017 Mar 12 ;273:1-9. Epub 2017 Mar 12. PMID:
28300665
Article Published Date
: Mar 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions
:
Anti-Fibrotic
,
Chemoprotective Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Grape-seed-derived procyanidin attenuates chemotherapy-induced cognitive impairment.
Apr 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Sci. 2022 Apr 28 ;12(5). Epub 2022 Apr 28. PMID:
35624958
Article Published Date
: Apr 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Chemoprotective Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Hesperidin protects against aluminum-induced renal injury.
Dec 21, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Sci Pollut Res Int. 2022 Dec 22. Epub 2022 Dec 22. PMID:
36547838
Article Published Date
: Dec 21, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Aluminum Toxicity
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Renoprotective
[+]
Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 ;7(7):5065-87. Epub 2015 Jun 24. PMID:
26115086
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Prostate Cancer
,
Prostate Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Hirsutanol A could be a useful agent for treating inflammatory diseases.
Jun 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2019 Jun 17 ;17(6). Epub 2019 Jun 17. PMID:
31213027
Article Published Date
: Jun 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Red Marine Algae
Diseases
:
Endotoxemia
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
STAT3 Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hispolon protects rats from liver damage from carbon tetrachloride.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:480714. Epub 2011 Oct 15. PMID:
22013489
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Phellinus Linteus
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
Apr 19, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurosci. 2015 Apr 20 ;16:22. Epub 2015 Apr 20. PMID:
25925889
Article Published Date
: Apr 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Hypertension
,
Oxidative Stress
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Hyperbaric oxygen therapy could inhibit glioma cell proliferation and inflammatory cell infiltration.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Med. 2016 Nov ;5(11):3147-3155. Epub 2016 Oct 13. PMID:
27734611
Article Published Date
: Oct 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Diseases
:
Glioma
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Chemosensitizer
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
I. obliquus can prevent the aging process by attenuating oxidative stress in a model of stress-induced premature senescence.
Apr 30, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Cells. 2011 May ;31(5):423-9. Epub 2011 Feb 22. PMID:
21359681
Article Published Date
: Apr 30, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Aging Skin
,
Lipid Peroxidation
,
Oxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Icariin attenuates perfluorooctane sulfonate-induced testicular toxicity.
Mar 20, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Mar 21 ;13(6):3674-3689. Epub 2022 Mar 21. PMID:
35262540
Article Published Date
: Mar 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Icariin
Diseases
:
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Sci Rep. 2016 ;6:21731. Epub 2016 Feb 25. PMID:
26911838
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
STAT3 Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Inhibitory effects of formononetin on the monocrotaline‑induced pulmonary arterial hypertension.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2020 Mar ;21(3):1192-1200. Epub 2020 Jan 3. PMID:
31922224
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Aug 04, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID:
31004603
Article Published Date
: Aug 04, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
Wnt/β-catenin signaling pathway modulation
[+]
Juglone may improve diabetic atherosclerosis by inhibiting proliferation and migration of VSMCs.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2020 ;2020:4196482. Epub 2020 Jul 23. PMID:
32774672
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Atherosclerosis
,
Diabetic Complications
Pharmacological Actions
:
Antiproliferative
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Kaempferol might act as a therapeutic potential candidate for cancer metastasis.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 2015 Feb ;93(1):16-27. Epub 2014 Sep 12. PMID:
25453494
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kaempferol
Diseases
:
Breast Cancer: Triple Negative
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Korean Red Ginseng extracts might have the ability to reduce the incidence of leukemia.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Oct ;40(4):431-436. Epub 2016 Aug 4. PMID:
27746697
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Lymphoma
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2021 03 ;89:108556. Epub 2020 Nov 26. PMID:
33249185
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Theanine
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.
May 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2013 Jun ;6(6):603-13. Epub 2013 Apr 26. PMID:
23625311
Article Published Date
: May 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Licorice
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Liquiritigenin potentiates the inhibitory effects of cisplatin on invasion and metastasis in B16F10 melanoma cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(5):761-70. Epub 2015 May 15. PMID:
25978595
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Liquiritigenin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Low molecular-weight fucoidan can be used as a skin-protective remedy for photoaging.
Aug 17, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2018 Aug 18 ;16(8). Epub 2018 Aug 18. PMID:
30126169
Article Published Date
: Aug 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Luteolin can be a chemotherapeutic agent against colorectal cancer.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2014 Nov ;33(11):1176-85. Epub 2014 Feb 14. PMID:
24532706
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells.
Jan 20, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jan 21. Epub 2019 Jan 21. PMID:
30663726
Article Published Date
: Jan 20, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Mangiferin reduces colonic damage in a murine model of colitis.
Jun 24, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Jun 25 ;253:18-26. Epub 2016 Apr 26. PMID:
27125760
Article Published Date
: Jun 24, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Melatonin has cardioprotective effects in a rat model of cardiorenal syndrome.
Jul 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27465663
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Heart Disease
,
Kidney Diseases
,
Multi-Organ Failure
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Melatonin restricts the periodontitis-induced inflammatory stress, apoptosis, and structural but not functional impairments.
Nov 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2020 Nov 30. Epub 2020 Nov 30. PMID:
33251634
Article Published Date
: Nov 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-8 (MMP-8) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Metformin in combination with curcumin inhibits the growth, metastasis and angiogenesis of hepatocellular carcinoma.
Aug 18, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2017 Aug 19. Epub 2017 Aug 19. PMID:
28833603
Article Published Date
: Aug 18, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Modulation of antioxidant potential with coenzyme Q10 suppressed invasion of temozolomide-resistant glioma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:3061607. Epub 2019 Mar 12. PMID:
30984333
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Chemotherapeutic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Momordica charantia exosome-like nanoparticles exert neuroprotective effects against ischemic brain injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:908830. Epub 2022 Jun 24. PMID:
35814200
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
Additional Keywords
:
Exosomes
[+]
Morroniside protects against cerebral ischemia/reperfusion injury.
Aug 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Sep ;16(3):2229-2234. Epub 2018 Jul 17. PMID:
30186462
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Dogwood
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Myricetin has potential anticancer activity and could be an important chemoprevention agent for bladder cancer.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2012 ;64(4):599-606. Epub 2012 Apr 6. PMID:
22482362
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Myricetin
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
NAC reduces hippocampal neuronal damage following transient global ischemia.
Nov 09, 2019
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2019 Nov 10. Epub 2019 Nov 10. PMID:
31722253
Article Published Date
: Nov 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Naringenin ameliorates diabetic neuropathic pain by modulation of oxidative-nitrosative stress, cytokines and MMP-9 levels.
May 12, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 May 13. Epub 2020 May 13. PMID:
32400767
Article Published Date
: May 12, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Naringenin
Diseases
:
Diabetic Neuropathy
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Naringenin inhibits UVB irradiation-induced skin damage and may be a promising therapeutic approach to control skin disease.
Jul 23, 2015
Click here to read the entire abstract
Pubmed Data
: J Nat Prod. 2015 Jul 24 ;78(7):1647-55. Epub 2015 Jul 8. PMID:
26154512
Article Published Date
: Jul 23, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Naringenin
Diseases
:
Inflammation
,
Skin Cancer
,
Skin Cancer: Prevention
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Antioxidants
,
Interferon Gamma Reducer
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Cytokines
[+]
Naringin may be a promising agent for the treatment of physical fatigue.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):423-427. PMID:
27937032
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Citrus naringin
Diseases
:
Fatigue
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Naturally fermented Noni juice manifests a protective potential on liver fibrosis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Chin Med Assoc. 2017 Apr ;80(4):212-221. Epub 2017 Mar 6. PMID:
28268174
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Noni
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury.
Mar 04, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar 5. Epub 2018 Mar 5. PMID:
29512719
Article Published Date
: Mar 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Neurovascular protection of salvianolic acid B and ginsenoside Rg1 combination against acute ischemic stroke.
Jan 07, 2021
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2021 09 8 ;32(13):1140-1146. PMID:
34284451
Article Published Date
: Jan 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Salvia miltiorrhiza
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Nimbolide ameliorates the streptozotocin-induced diabetic retinopathy.
Jul 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Biol Sci. 2021 Aug ;28(8):4255-4262. Epub 2021 Jun 19. PMID:
34354407
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Neem
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Nobiletin ameliorates the cardiovascular dysfunction of diabetes by inhibiting oxidative stress, MMP-2 and MMP-9.
Jul 12, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jul 13 ;7(7):3121-9. PMID:
27279123
Article Published Date
: Jul 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Cardiovascular Diseases
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Notoginsenoside R1 facilitated wound healing in high-fat diet/streptozotocin-induced diabetic rats.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2022 ;2022:2476493. Epub 2022 Jan 13. PMID:
35069970
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Oleanolic acid exerts inhibitory effects on the late stage of osteoclastogenesis and prevents bone loss in osteoprotegerin knockout mice.
Jul 17, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 Jul 18. Epub 2019 Jul 18. PMID:
31318102
Article Published Date
: Jul 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Oleanolic acid
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Osteoprotective
[+]
Oral administration of black ginger extract significantly prevents UVB-induced photoaging in hairless mice.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Photodermatol Photoimmunol Photomed. 2014 Oct ;30(5):237-45. Epub 2014 Jan 9. PMID:
24313661
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Kaempferia parviflora
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Photoprotective
Additional Keywords
:
Plant Extracts
[+]
Oral Aloe vera gel powder has the ability to prevent the skin photoaging.
Apr 03, 2016
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2016 Apr 4:1-9. Epub 2016 Apr 4. PMID:
27045316
Article Published Date
: Apr 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Paeoniflorin attenuates postoperative pain by suppressing matrix metalloproteinase-9/2 in mice.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pain. 2018 02 ;22(2):272-281. Epub 2017 Oct 29. PMID:
29081070
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Allodynia
,
Hyperalgesia
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Paeonol exerts anti-angiogenic and anti-metastatic activities.
Jun 30, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2009 Jul ;32(7):1142-7. PMID:
19571375
Article Published Date
: Jun 30, 2009
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeonol
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Palmitoylethanolamide and polydatin treatment causes endometriotic lesion regression.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:382. Epub 2016 Oct 14. PMID:
27790149
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Endometriosis
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Panaxadiol as a major metabolite of AD-1 can significantly inhibit the proliferation and migration of breast cancer cells.
Jan 10, 2021
Click here to read the entire abstract
Pubmed Data
: Bioorg Chem. 2021 11 ;116:105392. Epub 2021 Sep 30. PMID:
34619469
Article Published Date
: Jan 10, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Panaxadiol
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells.
Oct 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2013 Oct 31 ;4:e891. Epub 2013 Oct 31. PMID:
24176849
Article Published Date
: Oct 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Parthenolide
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Pharmacological effects of natural components against ovarian cancer and mechanisms.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Adv Exp Med Biol. 2021 ;1330:55-73. PMID:
34339030
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
,
Lignans
,
Luteolin
,
Mangiferin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Pinocembrin pretreatment may represent a novel means of increasing the safety and the therapeutic time window of t-PA following ischemic stroke.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2018 ;2018:8943210. Epub 2018 Apr 22. PMID:
29850586
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Ischemia
,
Stroke
,
Thrombosis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Piperlongumine suppresses growth and sensitizes pancreatic tumors to gemcitabine in a xenograft mouse model.
Dec 13, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2015 Dec 14. Epub 2015 Dec 14. PMID:
26667450
Article Published Date
: Dec 13, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Long Pepper
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Bcl-2 protein down-regulation
,
Chemosensitizer
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Survivin Down-Regulation
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
[+]
Pro-apoptotic, anti-metastatic, and anti-telomerase activity of Tinospora cordifolia and its active polysaccharide arabinogalactan during Benzo(a)pyrene-induced lung carcinogenesis.
Apr 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Indian J Pharmacol. 2022 May-Jun;54(3):198-207. PMID:
35848691
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Guduchi
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
,
Polysaccharides
[+]
Propolis enhances cutaneous wound healing by promoting TGF-Beta/Smad-mediated collagen production in a streptozotocin-induced type I diabetic mouse model.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2015;37(3):940-954. Epub 2015 Sep 18. PMID:
26381245
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Bee
Diseases
:
Diabetes Mellitus: Type 1
,
Wound Healing
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Protective effects of paeoniflorin on alveolar bone resorption and soft-tissue breakdown in experimental periodontitis.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Periodontal Res. 2016 Apr ;51(2):257-64. Epub 2015 Jul 14. PMID:
26179445
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Protective role of black tea flavonoids against ethanol-induced gastropathy via matrix metalloproteinase pathway.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2019 Oct ;34(4):379-394. Epub 2018 Aug 23. PMID:
31686725
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
Alcohol Toxicity
,
Gastrointestinal Diseases
Pharmacological Actions
:
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Quercetin alleviates pulmonary fibrosis in mice exposed to silica by inhibiting macrophage senescence.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:912029. Epub 2022 Jul 26. PMID:
35959439
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Pulmonary Fibrosis
,
Silicosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Quercetin has a certain therapeutic effect on rats with diabetic retinopathy.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Dec ;14(6):6022-6026. Epub 2017 Oct 10. PMID:
29285153
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Quercetin reduces oxidative stress and inhibits activation of c Jun N terminal kinase/activator protein 1 signalling.
Jan 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2014 Feb ;9(2):435-42. Epub 2013 Dec 6. PMID:
24337353
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Aneurysm: Aortic
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Regular boysenberry consumption has the potential to moderate chronic lung remodelling and fibrosis in asthma and other chronic pulmonary diseases.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1 ;311(3):L628-38. Epub 2016 Jul 1. PMID:
27371734
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Berries: All
Diseases
:
Asthma
,
Fibrosis
,
Lung Diseases
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2011 Dec ;171(2):e237-46. Epub 2011 Aug 24. PMID:
21962734
Article Published Date
: Nov 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Resveratrol downregulates the TLR4 signaling pathway to reduce brain damage in a rat model of focal cerebral ischemia.
Mar 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Apr ;17(4):3215-3221. Epub 2019 Feb 27. PMID:
30936996
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol reduces hippocampal neuronal cell damage following transient global ischemia by reducing MMP-9 activity.
Sep 02, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Sep 3. Epub 2015 Sep 3. PMID:
26421359
Article Published Date
: Sep 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Rosmarinic acid suppresses abdominal aortic aneurysm progression in apolipoprotein E-deficient mice.
Nov 04, 2021
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2021 Nov 5. Epub 2021 Nov 5. PMID:
34741296
Article Published Date
: Nov 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Aneurysm
Pharmacological Actions
:
Anti-Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Saffron aqueous extract exerted dose-dependent anti-atherosclerotic and plaque-stabilizing effects in mice.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2017 Nov 1. Epub 2017 Nov 1. PMID:
29128090
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-atherogenic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Salvianolic acid C significantly ameliorated the progression of aortic aneurysm in mice.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Dec 1 ;166:75-81. Epub 2016 Sep 20. PMID:
27663582
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Red Sage
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sea buckthorn has potential as a protective and therapeutic treatment candidate against skin aging.
Jul 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2012 Aug ;30(2):392-400. Epub 2012 May 24. PMID:
22641502
Article Published Date
: Jul 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sea buckthorn
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Sea cucumber extract TBL-12 could suppress the proliferation and metastasis of human prostate cancer cells.
Mar 18, 2019
Click here to read the entire abstract
Pubmed Data
: Prostate. 2019 Mar 19. Epub 2019 Mar 19. PMID:
30889629
Article Published Date
: Mar 18, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sea Cucumber
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2018 06 ;16:169-178. Epub 2018 Mar 1. PMID:
29505920
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
Immunomodulatory
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Selective Cytotoxicity
[+]
Sesamol attenuates experimentally induced myocardial infarction.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2011 ;27(3-4):273-80. Epub 2011 Apr 1. PMID:
21471716
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Sesamol
Diseases
:
Hypertension
,
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome.
Jun 17, 2011
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Biophys. 2011 Jun 17. Epub 2011 Jun 17. PMID:
21681587
Article Published Date
: Jun 17, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Sesamol
Diseases
:
Sinusoidal obstruction syndrome
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sika deer (Cervus nippon) velvet antler extract attenuates prostate cancer in xenograft model.
Jan 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biosci Biotechnol Biochem. 2019 Feb ;83(2):348-356. Epub 2018 Oct 31. PMID:
30381032
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Velvet antler
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis.
Oct 02, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Oct 3 ;13(19):9973-9987. Epub 2022 Oct 3. PMID:
36056701
Article Published Date
: Oct 02, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sulforaphane may be a potential a candidate for use in the treatment of acute lung injury.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2016 Jan ;37(1):182-8. Epub 2015 Oct 27. PMID:
26531002
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-E2-Related Factor-2 (Nrf2) Modulator
,
Prostaglandin PGE2 downregulation
[+]
Sulforaphane reduces inflammation following spinal cord injury in mice.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ann Clin Lab Sci. 2010;40(4):354-60. PMID:
20947810
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Supplementation with lycopene-enriched tomato extract may counteract hepatocellular carcinoma progression or protect against disease onset.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Nov-Dec;67(8):1268-75. Epub 2015 Oct 16. PMID:
26474105
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
,
Tomato
Diseases
:
Liver Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Anticarcinogenic Agents
,
Chemopreventive
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Synthetic cannabinoids inhibited growth, migration and invasion of NSCLC cells in in vitro as well as in vivo in a mouse model.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jan ;4(1):65-75. Epub 2010 Nov 19. PMID:
21097714
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids: Synthetic
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Cannabinoid Receptors
[+]
Systemic administration of luteolin promotes wound restoration by ameliorating inflammation and oxidative stress.
Jun 29, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomedicines. 2021 Jun 30 ;9(7). Epub 2021 Jun 30. PMID:
34209369
Article Published Date
: Jun 29, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Diabetic Complications
,
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Tanshinone IIA attenuates the development of elastase-induced experimental abdominal aortic aneurysms.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Zhonghua Wai Ke Za Zhi. 2012 Oct ;50(10):923-7. PMID:
23302465
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152.
Dec 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Rep. 2019 Dec 31. Epub 2019 Dec 31. PMID:
31894340
Article Published Date
: Dec 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemothapeutic Synergy: Imatinib
[+]
Tanshinone IIA relieves arthritis by inhibiting autophagy of fibroblast-like synoviocytes.
Mar 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytother Res. 2023 Apr ;37(4):1391-1404. Epub 2023 Feb 28. PMID:
36852883
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Arthritis
,
Rheumatoid Arthritis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Tanshinone IIA suppresses glioma cell oroliferation, migration and invasion.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Manag Res. 2020 ;12:11309-11320. Epub 2020 Nov 6. PMID:
33192091
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Glioma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
[+]
Tetramethylpyrazine may be a potential candidate for neuropathic pain treatment.
Aug 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2017 Aug 31 ;14(1):174. Epub 2017 Aug 31. PMID:
28859670
Article Published Date
: Aug 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ligustrazine
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vasodilator Agents
[+]
The combination of CS plus metronomic ZOL demonstrated significant antitumor, anti-metastatic and anti-osteolytic effects against breast cancer
May 19, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 May 20. Epub 2015 May 20. PMID:
25998578
Article Published Date
: May 19, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Green Tea
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
Problem Substances
:
Zoledronic Acid
[+]
The dibenzyl isoquinoline alkaloid berbamine ameliorates osteoporosis by inhibiting bone resorption.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Endocrinol (Lausanne). 2022 ;13:885507. Epub 2022 May 18. PMID:
35663327
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berbamine
Diseases
:
Osteoporosis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Osteoprotective
[+]
The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.
Dec 19, 2016
Click here to read the entire abstract
Pubmed Data
: Photodermatol Photoimmunol Photomed. 2016 Dec 20. Epub 2016 Dec 20. PMID:
27995657
Article Published Date
: Dec 19, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Aloe vera
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Ultraviolet Radiation Induced Damage
[+]
The effect of rice bran extract on arterial blood pressure, hepatic steatosis, and inflammation in mice fed with a high-fat diet.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr Metab. 2020 ;2020:8374287. Epub 2020 Jun 26. PMID:
32685208
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Rice Bran
Diseases
:
Hepatic Steatosis
,
High Fat Diet
,
Hypertension
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
The main components of pomegranate can inhibit metastasis of ovarian cancer.
Nov 26, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2017 Nov 27:1-10. Epub 2017 Nov 27. PMID:
29173024
Article Published Date
: Nov 26, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
,
Luteolin
,
Pomegranate
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
The results suggested that taxifolin has a therapeutic potential for osteoclastogenesis-related diseases.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2019 ;103(1-2):101-109. Epub 2018 Dec 6. PMID:
30522105
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoporosis
,
Rheumatoid Arthritis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Osteoprotective
[+]
Theaflavins have therapeutic potential in the treatment of periodontal disease.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Periodontal Res. 2018 Dec ;53(6):1009-1019. Epub 2018 Aug 30. PMID:
30159985
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Theaflavins
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Therapeutic applications of garlic and turmeric for the diabetic wound healing in mice.
Nov 03, 2022
Click here to read the entire abstract
Pubmed Data
: J Burn Care Res. 2022 Nov 4. Epub 2022 Nov 4. PMID:
36331804
Article Published Date
: Nov 03, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Turmeric
Diseases
:
Diabetic Complications
,
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
These data indicate that quercetin may be useful for the prevention and treatment of abdominal aortic aneurysms.
Sep 04, 2012
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2012 Sep 5 ;690(1-3):133-41. Epub 2012 Jun 19. PMID:
22728078
Article Published Date
: Sep 04, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings represent the promising anti-schistosomal activities of probiotics and yogurt.
Jan 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2019 Jan 3 ;19(1):3. Epub 2019 Jan 3. PMID:
30606163
Article Published Date
: Jan 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Lipid Peroxidation
,
Liver Cirrhosis
,
Oxidative Stress
,
Schistosomiasis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings reveal a new potential therapeutic application of curcumin in anti-metastatic therapy for endometrial carcinoma.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2015 Sep ;10(3):1297-1302. Epub 2015 Jul 9. PMID:
26622667
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings show that baicalein is an effective agent for abdominal aortic aneurysm prevention.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Sci China Life Sci. 2016 Sep ;59(9):940-9. Epub 2016 Jun 22. PMID:
27333787
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These results demonstrate a novel role of eicosapentaenoic acid in attenuating abdominal aortic aneurysm formation.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(5):e96286. Epub 2014 May 5. PMID:
24798452
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These results demonstrated that salvianolic acid A held great potential for aortic aneurysm therapy.
Sep 14, 2014
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2014 Sep 15 ;21(10):1137-45. Epub 2014 Jun 7. PMID:
24916705
Article Published Date
: Sep 14, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aortic Aneurysm
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
These results suggest a potential therapeutic role of isoliquiritigenin to treat osteoarthritis.
Jun 14, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Ther Methods Clin Dev. 2018 Jun 15 ;9:153-159. Epub 2018 Feb 15. PMID:
29766025
Article Published Date
: Jun 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
These results suggest that piperine free P. nigrum extracts can enhance breast cancer cell response to phytochemicals.
May 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 May 4. Epub 2016 May 4. PMID:
27155135
Article Published Date
: May 03, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Black Pepper
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Suppressor Protein p53 Upregulation
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Bioenhancer
,
Natural Substance Synergy
[+]
These results suggest that treatment with EGb 761 in mice prevented the development of CaCl2-induced abdominal aortic aneurysm.
Oct 27, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Oct 28 ;150(1):308-15. Epub 2013 Sep 5. PMID:
24012526
Article Published Date
: Oct 27, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
This study demonstrated tanshinone IIA suppressed the progression of atherosclerosis.
Apr 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Open. 2017 Apr 15 ;6(4):489-495. Epub 2017 Apr 15. PMID:
28412716
Article Published Date
: Apr 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
This study provides evidence for the beneficial effects of far-infrared therapy exposure in a model of skin photoaging.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0174042. Epub 2017 Mar 16. PMID:
28301572
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Ultraviolet Radiation Induced Damage
Therapeutic Actions
:
Thermal Therapy: Far-Infrared
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
This study provides evidence that morin may have anticancer effects against metastatic breast cancer.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2014 Oct ;45(4):1629-37. Epub 2014 Jul 4. PMID:
24993541
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Flavonoids
,
Mulberry
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
This study shows asiatic acid is effective against multiple models of focal ischemia.
May 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Stroke. 2012 Jun ;43(6):1632-8. Epub 2012 Apr 17. PMID:
22511009
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Stroke
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
This study suggests an effect of apple polyphenols and apple anthocyanin Cy3Gal against colon carcinogenesis.
May 18, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2020 May 19 ;83:108418. Epub 2020 May 19. PMID:
32592950
Article Published Date
: May 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Thuja orientalis reduces airway inflammation in ovalbumin-induced allergic asthma.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2015 Sep ;12(3):4640-4646. Epub 2015 Jun 11. PMID:
26063078
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thuja
Diseases
:
Asthma
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Thymoquinone suppresses angiogenesis in DEN-induced hepatocellular carcinoma by targeting miR-1-3p.
Dec 13, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Dec 14 ;23(24). Epub 2022 Dec 14. PMID:
36555545
Article Published Date
: Dec 13, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Liver Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Tomatidine suppresses the destructive behaviors of fibroblast-like synoviocytes.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:670707. Epub 2021 Aug 26. PMID:
34512321
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Tomatidine
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Total saponins from Rosa laevigata can be applied as one effective candidate for the treatment of liver fibrosis.
Jun 14, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 Jun 15 ;7(6):4829-50. Epub 2015 Jun 15. PMID:
26083117
Article Published Date
: Jun 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Treatment of berberine alleviates diabetic nephropathy by reducing iron overload and inhibiting oxidative stress.
Feb 23, 2023
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 2023 Feb 24:18599. Epub 2023 Feb 24. PMID:
36861878
Article Published Date
: Feb 23, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Diabetic Nephropathy
,
Iron Overload
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Renoprotective
[+]
Triptolide inhibited B16F10 cell migration and invasion via the inhibition of NF-κB expression
Sep 28, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2015 Sep 29. Epub 2015 Sep 29. PMID:
26420756
Article Published Date
: Sep 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Triptolide
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Tristetraprolin: A novel target of diallyl disulfide that inhibits the progression of breast cancer.
Apr 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 May ;15(5):7817-7827. Epub 2018 Mar 20. PMID:
29725473
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ursolic acid ameliorated the severity of abdominal aortic aneurysms.
Feb 14, 2018
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2018 Feb 15 ;271:128-135. Epub 2018 Feb 15. PMID:
29499360
Article Published Date
: Feb 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ursolic Acid
Diseases
:
Aortic Aneurysm
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Verbascoside has potential use as a potent anticancer agent in oral squamous cell carcinoma therapeutic strategies.
Aug 14, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2018 Aug 15 ;143(4):980-991. Epub 2018 Apr 16. PMID:
29536537
Article Published Date
: Aug 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Vitamin C in combination with vitamin K3 inhibits primary tumor growth and exhibits antimetastastic potential in vivo through attenuated tumor invasion and proliferation.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2011 ;63(7):1036-43. Epub 2011 Sep 2. PMID:
21888506
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
,
Vitamin K
Diseases
:
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Disease Regression
,
Dose Response
[+]
Vitamin E has a potential role as an atheroprotective agent in early and established atherosclerosis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2016 ;60:31525. Epub 2016 Oct 28. PMID:
27799085
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E: alpha tocopherol
,
Vitamin E: Gamma-tocotrienol
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Coronary Artery Disease
Pharmacological Actions
:
Anti-atherogenic
,
Cardioprotective
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Risk Reduction
[+]
Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jan 12 ;7(2):1544-58. PMID:
26637807
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Zerumbone
Diseases
:
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.
Jul 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jul 26 ;7(30):47232-47241. PMID:
27323807
Article Published Date
: Jul 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Cancers: All
Pharmacological Actions
:
angiogenesis
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
β-Carotene is a potent anti-inflammatory agent that improves the barrier functions of atopic dermatitis skin.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2019 Sep ;28(9):1044-1050. Epub 2019 Aug 8. PMID:
31287602
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
beta-Carotene
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Inhibition of programmed death ligand 1 (PD-L1) expression in breast cancer cells by sesamin.
Aug 31, 2020
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2020 Sep ;86:106759. Epub 2020 Jul 11. PMID:
32663768
Article Published Date
: Aug 31, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Sesamin
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Theaflavins suppress the growth and metastasis of human hepatocellular carcinoma.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2016 ;9:4265-75. Epub 2016 Jul 14. PMID:
27478384
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Theaflavins
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
"Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells."
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2008 Jul-Aug;62(6):366-72. Epub 2007 Oct 22. PMID:
17988825
Article Published Date
: Jul 01, 2008
Study Type
: In Vitro Study
Additional Links
Substances
:
Resveratrol
,
Stilbenes
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
2,3,5,4 tetrahydroxy diphenylethylene 2 O glucoside inhibits the adhesion and invasion of A549 human lung cancer cells.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2017 Dec ;16(6):8900-8906. Epub 2017 Oct 2. PMID:
28990072
Article Published Date
: Nov 30, 2017
Study Type
: In Vitro Study
Additional Links
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
3,4,5-trihydroxybenzaldehyde from Geum japonicum has dual inhibitory effect on matrix metalloproteinase 9; inhibition of gelatinoytic activity.
Sep 30, 2008
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2008 Oct 1 ;105(2):524-33. PMID:
18773430
Article Published Date
: Sep 30, 2008
Study Type
: In Vitro Study
Additional Links
Substances
:
Geum japonicum
,
Herb Bennet
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2010 Dec ;161(8):1763-77. PMID:
20718733
Article Published Date
: Dec 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer.
Oct 29, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2019 Oct 30. Epub 2019 Oct 30. PMID:
31673889
Article Published Date
: Oct 29, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Black Tea
,
Citrus Peel
,
Orange: Mandarin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
A hydroalcoholic extract of oak acorn shell acts as a potent antiangiogenic agent.
Feb 28, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2013 Mar ;51(3):361-8. Epub 2012 Nov 8. PMID:
23137183
Article Published Date
: Feb 28, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Oak
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A novel function of artesunate on inhibiting migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients.
Jun 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Arthritis Res Ther. 2019 Jun 24 ;21(1):153. Epub 2019 Jun 24. PMID:
31234900
Article Published Date
: Jun 23, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Artesunate
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A review of formononetin and its anticancer potentials and mechanisms.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:820. Epub 2019 Jul 26. PMID:
31402861
Article Published Date
: Dec 31, 2018
Study Type
: Review
Additional Links
Substances
:
Formononetin
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Chemopreventive
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
A Rheum palmatum extract has potential anti-metastatic activity.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2015 Jul ;40(1):30-8. Epub 2015 May 16. PMID:
26056975
Article Published Date
: Jun 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Rhubarb
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
A rice bran phytochemical, cyanidin 3-glucoside, inhibits the progression of PC3 prostate cancer cell.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Anat Cell Biol. 2020 Aug 25. Epub 2020 Aug 25. PMID:
32839357
Article Published Date
: Aug 24, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Cyanidin 3-glucoside
,
Rice Bran
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
A standardized Terminalia chebula fruit extract alters the expression of genes associated with skin architecture and barrier formation.
Oct 05, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Dermatol. 2020 Oct 6. Epub 2020 Oct 6. PMID:
33021480
Article Published Date
: Oct 05, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Terminalia chebula
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
A water extract of Rosa hybrida has the potential to act as a novel agent for the prevention and treatment of vascular diseases.
Feb 24, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2016 Feb 25. Epub 2016 Feb 25. PMID:
26935151
Article Published Date
: Feb 24, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Rose
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
P21 Activation
[+]
A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects.
Mar 02, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Mar 3 ;7:43789. Epub 2017 Mar 3. PMID:
28256567
Article Published Date
: Mar 02, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Wogonin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chondroprotective
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Acanthopanax senticosus polysaccharide suppressed the proliferation and metastasis of the human non-small cell lung cancer NCI-H520 cells.
Jul 22, 2019
Click here to read the entire abstract
Pubmed Data
: Neoplasma. 2019 Jul 23 ;66(4):555-563. Epub 2019 Mar 30. PMID:
30943746
Article Published Date
: Jul 22, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginseng (Siberian)
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Polysaccharides
[+]
Achillea fragrantissima possesses anti-neuroinflammatory activities for prevention or treatment of neurodegenerative diseases.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2011 ;11:98. Epub 2011 Oct 21. PMID:
22018032
Article Published Date
: Dec 31, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Achillea fragrantissima
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Acteoside has the potential to be a potent anticancer agent in therapeutic strategies for fibrosarcoma metastasis.
Apr 30, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2011 May ;55 Suppl 1:S103-16. Epub 2010 Nov 18. PMID:
21089054
Article Published Date
: Apr 30, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Fibrosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Advances in research on the relationship between thymoquinone and pancreatic cancer.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2022 ;12:1092020. Epub 2023 Jan 4. PMID:
36686732
Article Published Date
: Dec 31, 2021
Study Type
: Review
Additional Links
Substances
:
Thymoquinone
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Allicin may be recognized as an anti-invasive agent for lung adenocarcinoma treatment.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Jul ;14(1):468-474. Epub 2017 May 5. PMID:
28693193
Article Published Date
: Jun 30, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Allyl isothiocyanate may be beneficial in the treatment of human colorectal adenocarcinoma in the future.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Rep. 2014 Jan ;31(1):189-96. Epub 2013 Nov 20. PMID:
24270601
Article Published Date
: Dec 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Aloin inhibits the proliferation and migration of gastric cancer cells.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:145-155. Epub 2020 Jan 14. PMID:
32021099
Article Published Date
: Dec 31, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
An alkaloid rich fraction from Nelumbo nucifera targets VSMC proliferation and migration to attenuate neo-intima formation.
Mar 20, 2016
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2016 Mar 21 ;248:179-189. Epub 2016 Mar 21. PMID:
27018542
Article Published Date
: Mar 20, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Atherosclerosis
,
Restenosis
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An ethanol extract of root of Prunus persica inhibited the growth of liver cancer cells.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:8231936. Epub 2017 Oct 12. PMID:
29234432
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Peach
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of holy basil significantly inhibited cell adhesion and invasion at nontoxic concentrations.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2014 ;14:419. Epub 2014 Oct 27. PMID:
25345853
Article Published Date
: Dec 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
PI3K/Akt/signaling suppression
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
An extract of Lotus may be a powerful agent against colon cancer cells.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Mar ;13(3):1470-1478. Epub 2016 Dec 28. PMID:
28454279
Article Published Date
: Feb 28, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Apoptotic
,
Bcl-2 protein down-regulation
,
COLON CANCER
,
Lotus
,
Plant Extracts
[+]
An extract of Z. cassumunar and its constituent should be benefit to ameliorate inflammation and hypersensitiveness of airway epithelium.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Allergy Immunol. 2015 Mar ;33(1):42-51. PMID:
25840633
Article Published Date
: Feb 28, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginger
Diseases
:
Allergic Airway Diseases
,
Allergies
,
Hypersensitivity: Respiratory
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Enzyme Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells.
Sep 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 Sep 28 ;10(1):15921. Epub 2020 Sep 28. PMID:
32985606
Article Published Date
: Sep 27, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Anthocyanin from the fruit of Vitis Coignetiae acts as a potent inhibitor of TNF-α effect by inhibiting NF-κB-regulated genes in human breast cancer cells.
May 20, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 May 21 ;25(10). Epub 2020 May 21. PMID:
32455624
Article Published Date
: May 20, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Grape
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-Inflammatory Agents
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Gene Expression Regulation
[+]
Anthocyanins from black rice could suppress CAL 27 cell metastasis by reduction of MMP-2, MMP-9, and NF-κB p65 expression.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(2):327-38. Epub 2015 Feb 6. PMID:
25658905
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Rice: Black
Diseases
:
Oral Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Anthocyanins isolated from fruits of Vitis coignetiae Pulliat inhibit cancer proliferation, cancer migration, and invasion.
Jan 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2017 11 26 ;18(11):2919-2923. Epub 2017 Nov 26. PMID:
29172259
Article Published Date
: Jan 25, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Grape
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cyclin D1 Down-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Cytokine. 2019 Apr ;116:48-60. Epub 2019 Jan 24. PMID:
30685603
Article Published Date
: Mar 31, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Quercetin
Diseases
:
Inflammation
,
Retinal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2013 Feb ;65(2):310-6. Epub 2012 Oct 22. PMID:
23278699
Article Published Date
: Jan 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Anti-invasive activity of anthocyanins isolated from Vitis coignetiae in human hepatocarcinoma cells.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Oct ;12(5):967-72. PMID:
19857058
Article Published Date
: Sep 30, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Grape
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anti-metastatic potential of natural triterpenoid cucurbitacin B against cholangiocarcinoma cells.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2022 Jan-Dec;21:15347354221124861. PMID:
36154723
Article Published Date
: Dec 31, 2021
Study Type
: In Vitro Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Anti-osteoarthritic effects of an herbal composition LI73014F2 on interleukin-1β-induced primary human articular chondrocytes.
Apr 26, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Apr 27 ;25(9). Epub 2020 Apr 27. PMID:
32349389
Article Published Date
: Apr 26, 2020
Study Type
: In Vitro Study
Additional Links
Substances
:
Frankincense
,
Terminalia chebula
,
Turmeric
Diseases
:
Osteoarthritis
Pharmacological Actions
:
5-Lipoxygenase Inhibitor
,