MicroRNA modulator

Name	AC	CK
Curcumin	44	68
Tanshinone IIA	36	57
Flavonoids	29	55
Resveratrol	22	53
Berberine	36	52
Ginsenosides	34	50
EGCG (Epigallocatechin gallate)	34	48
Polyphenols	17	31
Astragaloside	20	27
Quercetin	22	27
Vitamin D	12	26
Crocin	9	25
Vitamin C	4	23
Astaxanthin	9	22
Puerarin	13	20
Sulforaphane	18	19
Goji	6	18
Paeonol	12	18
Genistein	12	17
Pterostilbene	11	16
Emodin	10	15
Fucoidan	5	15
Apigenin	11	14
Grape	3	14
Nigella sativa (aka Black Seed)	3	14
Luteolin	10	13
Icariin	7	12
Licorice	10	12
Panax Notoginseng	7	12
Probiotics	2	12
Purslane	2	12
Rutin	2	12
Shikonin	10	12
Oleanolic acid	2	11
Salvia miltiorrhiza	7	11
Artichoke	1	10
Brazil nut	1	10
Chlorella (Algae)	1	10
Chocolate	1	10
Citrus naringin	6	10
Formononetin	8	10
Melatonin	8	10
Myricetin	4	10
Naringenin	6	10
Nuts	1	10
Olive	1	10
Orange	1	10
Thymoquinone	7	10
Tocotrienol: Alpha	1	10
Vitamin B-12	1	10
Baicalein	8	9
Mulberry	6	9
Oridonin	4	9
Curcumol	7	8
Delta-tetrahydrocannabinol (THC)	4	8
Ellagic Acid	5	8
Ginkgo biloba	5	8
Indole-3-Carbinol	5	8
Lactobacillus plantarum	5	8
Spirulina	3	8
Xanthohumol	6	8
Blueberry	6	7
Kaempferol	6	7
Nobiletin	6	7
Peony	5	7
Piperine	4	7
Reishi Mushroom	5	7
Selenium	4	7
Silibinin	6	7
Ursolic Acid	6	7
Angelica	6	6
Asiatic Acid	4	6
Cucurbitacin E	4	6
Diosgenin	3	6
Gastrodin	5	6
Ginger	4	6
Grape Seed Extract	4	6
Ligustrazine	5	6
Oleuropein	6	6
Pomegranate	3	6
Royal Jelly	2	6
Tangeretin	3	6
Beta-Elemene	4	5
Cucurbitacin B	3	5
Delphinidin	3	5
Fermented Foods and Beverages	3	5
Gallic Acid	3	5
Ginseng (Siberian)	1	5
Hesperidin	4	5
Honokiol	4	5
Isoliquiritigenin	3	5
Moringa oleifera	3	5
Silymarin	1	5
Vitamin E	3	5
Vitamin K2	1	5
Allicin	3	4
Andrographolide	3	4
Ashwagandha	4	4
Carnosic Acid	3	4
Flaxseed	2	4
Garlic	4	4
Genipin	2	4
Glycyrrhizin	2	4
Indian Mulberry	2	4
Isoflavones	3	4
Lotus	4	4
Mangiferin	4	4
NAC (N-acetyl-L-cysteine)	2	4
Paeoniflorin	4	4
Aloe Vera	2	3
Anthocyanins	2	3
Apple Polyphenols	2	3
Artesunate	3	3
Barley	2	3
Bee Venom	2	3
Betulinic acid	2	3
Bufalin	3	3
Catechin	3	3
Celastrol	3	3
Chlorogenic Acid	3	3
Gingerol	2	3
Ginseng (Korean)	2	3
Green Tea	2	3
Lactoferrin	3	3
Omega-3 Fatty Acids	2	3
Polyunsaturated Fatty Acids (PUFAs)	2	3
Prunella vulgaris	2	3
Sinomenine	3	3
Tocotrienol: Delta	2	3
Walnut	2	3
2-Methoxyestradiol	1	2
Achiote	1	2
Alpha Linolenic Acid	1	2
Amla Fruit	1	2
Apple	1	2
Babchi	1	2
Benzyl isothiocyanate	2	2
Beta-Caryophyllene	1	2
Black Raspberry	2	2
Boswellia	1	2
Butyrate	2	2
Caffeic Acid	1	2
Caffeic acid phenethyl ester	1	2
Cannabidiol	2	2
Cannabis	1	2
Capsaicin	1	2
Carotenoids	1	2
Chokeberry	1	2
Chrysin	2	2
Coenzyme Q10	1	2
Coffee	1	2
Cordyceps sinensis	1	2
Corn Silk	1	2
Cranberry	1	2
Crocetin	1	2
Cryptoxanthin	1	2
Cucurbitacin D	1	2
Dandelion	2	2
Dill	1	2
Diosmetin	1	2
Evodiamine	1	2
Fish Oil	1	2
Fruit: All	1	2
Geraniol	1	2
Gold (nanoparticles)	1	2
Gotu Kola	1	2
Gynostemma	1	2
Hawthorn	1	2
Isoquercitrin	1	2
Isothiocyanates	2	2
Jambul	1	2
Litchi	1	2
Lychee	1	2
Lycopene	1	2
Magnolia	1	2
Magnolol	2	2
Maitake Mushroom	1	2
Mango	1	2
Mangosteen	1	2
Noni	1	2
Nordihydroguaiaretic acid (NDGA)	1	2
Organosulfur Compounds	2	2
Papaya	1	2
Patchouli	1	2
Phellinus Linteus	1	2
Piceatannol	2	2
Pine Nut	1	2
Pineapple	1	2
Piperlongumine	2	2
Potato: Pigmented	1	2
Pumpkin Seeds	1	2
Punicalagin	1	2
Pycnogenol (Pine Bark)	1	2
Rice Bran	1	2
S-Adenosylmethionine (SAMe)	2	2
Sweet Potato: Purple	1	2
Tocotrienols	1	2
Tripterygium wilfordii	1	2
Triptolide	1	2
Turmeric	1	2
Verbascoside	2	2
Vitamin A	2	2
Vitamin E: Gamma-tocotrienol	1	2
Vitamin E: alpha tocopherol	1	2
Vitexins	1	2
Zinc	1	2
beta-Carotene	1	2
6-Shogaol	1	1
Alpha-Lipoic Acid	1	1
Arctigenin	1	1
Astragalus	1	1
Berbamine	1	1
Bergamot	1	1
Beta Sitosterol	1	1
Bifidobacterium Bifidum	1	1
Bitter Orange	1	1
Cafestol	1	1
Camel Milk	1	1
Cardamonin	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Citrus Peel	1	1
Cordyceps Militaris	1	1
Cruciferous Vegetables	1	1
Curcuminoids	1	1
Cyanidin 3-glucoside	1	1
Demethoxycurcumin	1	1
Echinacea	1	1
Eggplant	1	1
Elecampane	1	1
Fiber	1	1
Folate	1	1
Folic Acid	1	1
Frankincense	1	1
Galactooligosaccharides	1	1
Garcinia indica	1	1
Huaier (Trametes robiniophila murr)	1	1
Hydroxytyrosol	1	1
Kahweol	1	1
Lactobacillus Acidophilus	1	1
Legumes	1	1
Lentinan	1	1
Liquiritigenin	1	1
Loquat	1	1
Mistletoe	1	1
Nettle	1	1
Oligosaccharides	1	1
Olive Oil	1	1
Olive leaf extract	1	1
Onion	1	1
Phenethyl isothiocyanate	1	1
Phospholipids	1	1
Plantago asiatica	1	1
Pomegranate Peel	1	1
Pomegranate Polyphenols	1	1
Propolis: Bee	1	1
Propolis: Brazillian	1	1
Psychedelics:All	1	1
Rhubarb	1	1
Rose	1	1
Rosemaric Acid	1	1
Seaweed: Brown	1	1
Sesamol	1	1
Shiitake Mushroom	1	1
Shitake Mushroom	1	1
Sweet Potato	1	1
Syrian rue	1	1
Tannic Acid	1	1
Theaflavins	1	1
Urolithin A	1	1
Velvet antler	1	1
Wogonin	1	1
Zerumbone	1	1
acetyl-11-keto-beta-boswellic acid	1	1

Article Published Date : Jan 13, 2021

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, MicroRNA modulator

[+]

The daily consumption of a high dose of vitamin C for 8 weeks resulted in enhanced anti-senescence and anti-atherosclerotic effects via an improvement of lipoprotein parameters.Sep 02, 2015

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Pubmed Data : Food Funct. 2015 Sep 3. Epub 2015 Sep 3. PMID: 26333284

Article Published Date : Sep 02, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Advanced Glycation End products (AGE)

Pharmacological Actions : Anti-atherogenic, Anti-Glycation Agents, Anti-Inflammatory Agents, Antioxidants, Hypolipidemic, MicroRNA modulator

[+]

The data support the strategy of flavonoid supplementation to mitigate post-exercise oxidative stress in endurance athletes.Nov 20, 2019

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Pubmed Data : Int J Sport Nutr Exerc Metab. 2019 Nov 21:1-8. Epub 2019 Nov 21. PMID: 31754080

Berberine can significantly inhibit the activity of N-acetyltransferase in human lung cancer cell line A549.May 31, 2014

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Pubmed Data : Adv Biol (Weinh). 2022 Dec ;6(12):e2200162. Epub 2022 Aug 26. PMID: 36026561

Article Published Date : Nov 30, 2022

Study Type : Animal Study

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Substances : Icariin

Diseases : Sarcopenia

Pharmacological Actions : MicroRNA modulator

[+]

Acacetin ameliorates insulin resistance in obesity.Mar 28, 2021

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Pubmed Data : Oncotarget. 2016 Apr 25. Epub 2016 Apr 25. PMID: 27129171

Article Published Date : Apr 24, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Amla Fruit

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator

Additional Keywords : Tumor Microenvironment

[+]

An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo. Oct 12, 2015

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Pubmed Data : Planta Med. 2015 Oct 13. Epub 2015 Oct 13. PMID: 26460672

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Pubmed Data : Nat Prod Res. 2015 Mar 16:1-5. Epub 2015 Mar 16. PMID: 25774691

Article Published Date : Mar 15, 2015

Study Type : Animal Study

Additional Links

Substances : Potato: Pigmented, Sweet Potato: Purple

Diseases : Alcoholic Liver Disease, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

Anti-obesity action of fermented barley extracts with Lactobacillus plantarum dy-1.Sep 30, 2019

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Pubmed Data : Biomed Environ Sci. 2019 Oct ;32(10):755-768. PMID: 31843045

Article Published Date : Sep 30, 2019

Study Type : Animal Study

Additional Links

Substances : Barley, Fermented Foods and Beverages, Lactobacillus plantarum

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Hepatoprotective, MicroRNA modulator

Additional Keywords : Anti-Obesity Agents

[+]

Antioxidant vtamins attenuate glyphosate-induced development of type-2 diabetes.Nov 30, 2023

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Pubmed Data : Cureus. 2023 Dec ;15(12):e51088. Epub 2023 Dec 25. PMID: 38274944

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Pubmed Data : Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID: 28282876

[+]

Berberine alleviates disease symptoms in mouse models mimicking the symptoms of IBS-D. Dec 31, 2014

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Crocin protected the liver against IR injury through increasing the activity of antioxidant enzymes.Dec 31, 2016

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Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:1702967. Epub 2017 Mar 6. PMID: 28367266

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Carotenoids, Crocin

Diseases : Liver Injury: Ischemia/reperfusion

Pharmacological Actions : Antioxidants, Hepatoprotective, MicroRNA modulator, Nrf2 activation

[+]

Crocin showed promising neuroprotective effects in rotenone-induced Parkinson's disease.Dec 03, 2019

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Pubmed Data : Neuropharmacology. 2019 Dec 4:107900. Epub 2019 Dec 4. PMID: 31811872

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Pubmed Data : Mol Nutr Food Res. 2015 Sep 23. Epub 2015 Sep 23. PMID: 26395192

Article Published Date : Sep 22, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Fructose-Induced Toxicity , High Fructose Diet, Proteinuria

Pharmacological Actions : MicroRNA modulator

[+]

Curcumin treated animals had a significant reduction in tumor growth as measured by the decrease in size of the subcutaneous xenografts compared to untreated animals.Jun 07, 2015

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Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26116834

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Pubmed Data : J Agric Food Chem. 2017 Jan 11 ;65(1):45-50. Epub 2016 Dec 29. PMID: 28000445

Article Published Date : Jan 10, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Delphinidin

Diseases : Muscle Atrophy

Pharmacological Actions : MicroRNA modulator

Additional Keywords : Delphinidin, MicroRNA modulator, Muscle Atrophy

[+]

Delta-tocotrienol protects human and mouse cells from radiation damage may through suppression of IL-1β-induced NFκB/miR-30 signaling. Dec 31, 2014

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Pubmed Data : Oncotarget. 2016 Mar 29 ;7(13):16158-71. PMID: 26930714

Article Published Date : Mar 28, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cancers: Drug Resistant, Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, MicroRNA modulator

Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: 5-flourouracil

[+]

EGCG induces miRNA profile changes in the NNK-induced A/J mouse lung tumor.Dec 31, 2013

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Pubmed Data : BMC Genomics. 2014 ;15 Suppl 11:S3. Epub 2014 Dec 16. PMID: 25559244

Epigallocatechin gallate ameliorates nicotine withdrawal conditions-induced somatic and affective behavior changes.Dec 31, 2022

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Gallic acid protects the liver in rats against injuries induced by transient ischemia-reperfusion.Mar 31, 2019

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Pubmed Data : FEBS J. 2018 Feb ;285(3):501-517. Epub 2017 Dec 26. PMID: 29197188

Article Published Date : Jan 31, 2018

Study Type : Animal Study

Additional Links

Substances : Genipin

Diseases : Hyperlipidemia

Pharmacological Actions : Hepatoprotective, Hypolipidemic, MicroRNA modulator

[+]

Genipin improves lipid metabolism and sperm parametersin obese mice via regulation of miR-132 expression.Sep 24, 2022

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Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2022 Sep 25 ;54(9):1278-1288. PMID: 36082932

Article Published Date : Sep 24, 2022

Study Type : Animal Study

Additional Links

Substances : Genipin

Diseases : Fatty Liver, Hyperlipidemia, Obesity

Pharmacological Actions : MicroRNA modulator

Additional Keywords : MicroRNA-135

[+]

Genistein alleviates high-fat diet-induced obesity.Apr 07, 2022

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Pubmed Data : Int Immunopharmacol. 2021 Jun ;95:107514. Epub 2021 Mar 4. PMID: 33677255

Article Published Date : May 31, 2021

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, MicroRNA modulator, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ginsenoside 20(S)-Rg3 inhibited the Warburg effect in ovarian cancer cells via H19/miR-324-5p/PKM2 pathway.Dec 31, 2017

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Pubmed Data : Cell Physiol Biochem. 2018 ;51(3):1340-1353. Epub 2018 Nov 27. PMID: 30481782

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Pubmed Data : Sci Rep. 2016 Sep 19 ;6:33709. Epub 2016 Aug 19. PMID: 27641158

Article Published Date : Sep 18, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Panax Notoginseng

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, MicroRNA modulator

Additional Keywords : Dose Response

[+]

Ginsenoside Rg-1 promoted the wound closure of diabetic foot ulcer.May 30, 2019

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Pubmed Data : Life Sci. 2019 May 31. Epub 2019 May 31. PMID: 31158376

Article Published Date : May 30, 2019

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Diabetic Ulcer

Pharmacological Actions : Anti-Ulcer Agents, MicroRNA modulator

[+]

Ginsenoside Rg1 attenuates lung injury in mice with type 2 diabetes mellitus-associated pulmonary tuberculosis.Dec 31, 2021

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Pubmed Data : Drug Deliv Transl Res. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31637677

Article Published Date : Oct 20, 2019

Study Type : Animal Study

Additional Links

Substances : Gold (nanoparticles)

Diseases : Albuminuria, Diabetic Nephropathy

Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor A Enhancer

[+]

Gotu kola plays an important role in preventing and curing diabetic nephropathy.Jan 07, 2018

Pubmed Data : Nutr Metab (Lond). 2018 ;15:86. Epub 2018 Dec 5. PMID: 30555521

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Gynostemma

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, MicroRNA modulator

[+]

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Pubmed Data : Biomed Pharmacother. 2022 Sep ;153:113411. Epub 2022 Jul 19. PMID: 36076481

Article Published Date : Aug 31, 2022

Korean red ginseng extract alleviated neurological impairment of myelin oligodendrocyte glycoprotein induced mouse model of chronic experimental autoimmune encephalomyelitis.Apr 06, 2015

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Pubmed Data : Mol Neurobiol. 2015 Apr 7. Epub 2015 Apr 7. PMID: 25846819

Article Published Date : Apr 06, 2015

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Ginsenosides

Diseases : Autoimmune Diseases, Encephalomyelitis

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Lactobacillus plantarum strain Ln4 attenuates diet-induced obesity, insulin resistance, and changes in hepatic mRNA levels.May 18, 2018

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Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:7943212. Epub 2018 Nov 15. PMID: 30581486

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Angiogenic, MicroRNA modulator

Additional Keywords : Polysaccharides

[+]

Lycium barbarum polysaccharides protects H9c2 cells from hypoxia-induced injury.Jan 31, 2019

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Pubmed Data : Biomed Pharmacother. 2019 Feb ;110:20-28. Epub 2018 Nov 17. PMID: 30458344

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Pubmed Data : Phytomedicine. 2018 Oct 22 ;57:18-29. Epub 2018 Oct 22. PMID: 30668319

Article Published Date : Oct 21, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator

[+]

MicroRNAs involved in the therapeutic functions of noni fruit juice in the treatment of acute gouty arthritis. Jul 14, 2021

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Pubmed Data : Foods. 2021 Jul 15 ;10(7). Epub 2021 Jul 15. PMID: 34359507

Article Published Date : Jul 14, 2021

Study Type : Animal Study

Additional Links

Substances : Noni

Diseases : Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

miR-222 is iInvolved in the amelioration effect of genistein on dexamethasone-induced skeletal muscle atrophy. Apr 28, 2022

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Pubmed Data : Nutrients. 2022 Apr 29 ;14(9). Epub 2022 Apr 29. PMID: 35565830

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Pubmed Data : Kaohsiung J Med Sci. 2022 Jul ;38(7):675-685. Epub 2022 May 20. PMID: 35593324

Article Published Date : Jun 30, 2022

Study Type : Animal Study

Additional Links

Substances : Indian Mulberry

Diseases : Osteoporosis

Pharmacological Actions : MicroRNA modulator, Osteoprotective

Additional Keywords : Polysaccharides

[+]

Moringa oleifera ethanolic extract attenuates tilmicosin-induced renal damage.Nov 12, 2020

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Pubmed Data : Sci Rep. 2016 ;6:20051. Epub 2016 Feb 3. PMID: 26837852

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cervical Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator

Additional Keywords : E6 Oncoprotein

Problem Substances : Benzo(a)pyrene

[+]

Naringenin alleviates myocardial ischemia reperfusion injury.Jul 31, 2021

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Pubmed Data : J Pharmacol Exp Ther. 2018 May ;365(2):281-290. Epub 2018 Feb 22. PMID: 29472517

Article Published Date : Apr 30, 2018

Study Type : Animal Study

Additional Links

Substances : Nordihydroguaiaretic acid (NDGA)

Diseases : Metabolic Diseases

Pharmacological Actions : Antioxidants, MicroRNA modulator

Anti Therapeutic Actions : Western Diet

[+]

Notoginsenoside R1 alleviates high glucose-induced inflammation and oxidative stress in HUVECs via upregulating miR-147a.Aug 08, 2021

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Pubmed Data : Food Sci Biotechnol. 2018 Oct ;27(5):1429-1438. Epub 2018 Apr 11. PMID: 30319853

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Pubmed Data : J Nutr Biochem. 2018 Apr 7 ;57:170-179. Epub 2018 Apr 7. PMID: 29734116

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Pubmed Data : Am J Transl Res. 2021 ;13(4):2006-2020. Epub 2021 Apr 15. PMID: 34017372

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Apigenin

Diseases : Diabetic Nephropathy

Pharmacological Actions : MicroRNA modulator, Renoprotective

[+]

Protective role of Spirulina platensis against bifenthrin-induced reprotoxicity.May 11, 2020

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[+]

Quercetin is able to protect BEAS-2B cells from hexavalent chromium-induced carcinogenesis.Jun 16, 2016

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Pubmed Data : Oncotarget. 2016 Jun 17. Epub 2016 Jun 17. PMID: 27344173

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Pubmed Data : J Ethnopharmacol. 2021 Oct 5 ;278:114289. Epub 2021 Jun 4. PMID: 34090908

Article Published Date : Oct 04, 2021

Study Type : Animal Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Obesity

Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator

Additional Keywords : Anti-Obesity Agents

[+]

Scleral vitamin D3 inhibits myopia development in mice.Jan 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cell Biochem. 2019 Nov 26. Epub 2019 Nov 26. PMID: 31769066

Article Published Date : Nov 25, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Lung Injury: Acute, Sepsis

Pharmacological Actions : MicroRNA modulator

Additional Keywords : Gene Expression Regulation

[+]

Silibinin inhibited tumor aggressiveness in head and neck squamous cell carcinomas.Jun 07, 2015

Click here to read the entire abstract

Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26090866

Article Published Date : Jun 07, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Silibinin

Diseases : Head and Neck Cancer

Pharmacological Actions : Antiproliferative , MicroRNA modulator

Additional Keywords : Dose Response

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View the Evidence: 890 Abstracts with MicroRNA modulator Research

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Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.Dec 04, 2016

Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos.Aug 19, 2022

B12 supplementation influences regulation of several metabolically important Type 2 diabetes-associated genes through methylation of miR21.Nov 13, 2017

Biological effects of rutin on skin aging.Jun 30, 2016

Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women.Nov 24, 2022

Brazil nut intake increases circulating miR-454-3p and miR-584-5p in obese women.Jun 30, 2019

Chlorella works for polycyclic aromatic hydrocarbon detoxification through the epigenetic modulation.Sep 11, 2015

Dark chocolate attenuates intracellular pro-inflammatory reactivity to acute psychosocial stress in men.Apr 27, 2016

Dietary components could have the ability to change miRNA expression, thereby modulating important pathways involved in lipid and glucose metabolism.Jan 28, 2021

Fatiguing freestyle swimming modifies miRNA profiles of circulating extracellular vesicles in athletes.May 11, 2023

Goji berry intake has antioxidative and anti-inflammatory effects in overweight and hypercholesterolemic subjects.Jan 17, 2017

Ketogenic diet induced shifts in the gut microbiome associate with changes to inflammatory cytokines and brain-related miRNAs.May 06, 2024

Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs.Nov 30, 2021

Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study.Feb 27, 2020

Role of resveratrol in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2.May 31, 2022

Role of δ-tocotrienol and resveratrol supplementation in the regulation of micro RNAs in patients with metabolic syndrome.May 31, 2023

Significant effect of crocin on the gene expression of MicroRNA-21 and MicroRNA-155 in patients with osteoarthritis.Jun 17, 2022

Tai Chi ameliorates coronary heart disease by affecting serum levels of miR-24 and miR-155.Dec 31, 2018

Tanshinone IIA improves ventricular remodeling following cardiac infarction by regulating miR-205-3p.Dec 31, 2020

The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus.Jan 13, 2021

The daily consumption of a high dose of vitamin C for 8 weeks resulted in enhanced anti-senescence and anti-atherosclerotic effects via an improvement of lipoprotein parameters.Sep 02, 2015

The data support the strategy of flavonoid supplementation to mitigate post-exercise oxidative stress in endurance athletes.Nov 20, 2019

The dietary intake of table grape affects circulating miRNAs levels in healthy subjects.Oct 31, 2021

The effect of nanomicelle curcumin supplementation and Nigella sativa oil on the expression level of miRNA-21, miRNA-422a, and miRNA-503 gene in postmenopausal women.Oct 31, 2021

There was a significant reduction of neopterin and IDO mRNA levels after the supplementation with probiotic.Dec 31, 2015

This data showed a clinical evidence that oleanolic acid could improve hyperlipidemia.Apr 30, 2018

This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.Aug 31, 2014

Vitamin C supplementation has beneficial effects for the male partners of couples with recurrent pregnancy loss could lead to improved pregnancy outcomes.Feb 29, 2020

Vitamin D supplementation could ameliorate AGEs–RAGE signaling pathway in T2DM patients.Dec 31, 2018

Whole-body vibration is a sufficient mechanical stimulus for altering c-miR-21-5p expression.Dec 31, 2021

Baicalin enhances the proliferation and invasion of trophoblasts and suppresses vascular endothelial damage in hypertensive disorder complicating pregnancy.Aug 31, 2021

Berberine can significantly inhibit the activity of N-acetyltransferase in human lung cancer cell line A549.May 31, 2014

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells.Dec 31, 2015

Puerarin attenuates preeclampsia-induced trophoblast mobility loss and inflammation by modulating miR-181b-5p/RBAK axis.Nov 06, 2021

Resveratrol markedly decreased the overexpression of miR-196b/miR-1290 and elevated IGFBP3 expression in the ALL cell lines.Dec 14, 2016

Royal jelly regulates the proliferation of human dermal microvascular endothelial cells through the down-regulation of a photoaging-related microRNA.Dec 31, 2018

Saponin extracts induced apoptosis of endometrial cells from women with endometriosis.Dec 31, 2016

Silymarin suppresses cellular inflammation by inducing reparative stress signaling.Aug 27, 2015

Spirulina platensis and related tetrapyrroles have potent antiproliferative effects on experimental human pancreatic cancer.Feb 28, 2014

The results of the present study suggested that vitamin K2 targets miR-133a to regulate osteogenesis.Apr 30, 2017

The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.Dec 31, 2014

3,3'-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells.Jun 29, 2022

Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion.Nov 30, 2022

Electroacupuncture-regulated miR-34a-3p/PDCD6 axis promotes post-spinal cord injury recovery.Dec 31, 2021

Icariin inhibits the malignant progression of lung cancer.May 31, 2022

Naringenin promotes angiogenesis of ischemic myocardium after myocardial infarction.Nov 30, 2022

Salvianolic acid A protects against acetaminophen-induced hepatotoxicity.Apr 02, 2023

Tangeretin synergizes with 5-fluorouracil to induce autophagy through MicroRNA-21 in colorectal cancer cells.Dec 31, 2021

Tanshinone IIA improves diabetes-induced renal fibrosis.Oct 31, 2022

Oridonin inhibition and miR‑200b‑3p/ZEB1 axis in human pancreatic cancer.Dec 31, 2016

Paeonol suppresses the effect of ox-LDL on mice vascular endothelial cells by regulating miR-338-3p/TET2 axis in atherosclerosis Aug 06, 2020

The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.Jul 21, 2020

Xanthohumol targets the ERK1/2‑Fra1 signaling axis to reduce cyclin D1 expression and inhibit non‑small cell lung cancer.Jul 19, 2020

1,8 cineole and ellagic acid inhibit hepatocarcinogenesis.Dec 31, 2021

2-Methoxyestradiol attenuates chronic-intermittent-hypoxia-induced pulmonary hypertension.Sep 23, 2018

6-Gingerol relieves myocardial ischaemia/reperfusion injury.Mar 22, 2021

A mechanistic insight into the potential anti-cancerous property of Nigella sativa on breast cancer.Aug 31, 2023

A phytomolecule icariin protects from sarcopenia.Nov 30, 2022

Acacetin ameliorates insulin resistance in obesity.Mar 28, 2021

Acupuncture improves insulin resistance in OLETF rats.Dec 31, 2015

Administration of chokeberry powder may help attenuate high-fat diet-induced NAFLD.Dec 31, 2015

Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis.Oct 03, 2021

Aloe-emodin attenuates myocardial infarction and apoptosis via up-regulating miR-133 expression.Jul 31, 2019

Aloin decelerates the progression of hepatocellular carcinoma through circ_0011385/miR-149-5p/WT1 axis.Jan 11, 2021

Alpha-mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders.Dec 05, 2019

Amla extract modulates cancer cells and the tumor microenvironment.Apr 24, 2016

An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo. Oct 12, 2015

Andrographolide suppresses osteoarthritis progression by regulating circ_Rapgef1/miR-383-3p/NLRP3 signaling axis.Mar 31, 2022

Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats.Feb 29, 2012

Anthocyanins from purple sweet potato and purple potato are good source of anti inflammatory phytochemicals to prevent alcoholic liver disease.Mar 15, 2015

Anti-obesity action of fermented barley extracts with Lactobacillus plantarum dy-1.Sep 30, 2019

MicroRNA modulator

View the Evidence:
890 Abstracts with MicroRNA modulator Research