Neurogenesis

Name	AC	CK
Ginsenosides	2	22
Curcumin	8	13
Bacopa	6	11
Alpha-Lipoic Acid	1	10
Astragaloside	5	10
Echinacea	1	10
Linoleic acid	1	10
Psychedelics:All	5	8
Gastrodin	3	6
Ginkgo biloba	4	6
Luteolin	3	6
Polyphenols	2	6
Ursolic Acid	3	6
Blueberry	1	5
Cannabinoids	4	5
Delta-tetrahydrocannabinol (THC)	4	5
Flavonoids	4	5
Ginger	1	5
Panax Notoginseng	3	5
Cannabidiol	4	4
Ginseng (Korean)	2	4
Hesperidin	2	4
Hydroxytyrosol	2	4
Melatonin	3	4
Moringa oleifera	2	4
Resveratrol	3	4
Rosemaric Acid	2	4
Silibinin	2	4
Thymoquinone	2	4
Astaxanthin	2	3
Crocin	2	3
Goji	2	3
Psilocybin	2	3
Reishi Mushroom	2	3
Salvia miltiorrhiza	2	3
Andrographis	1	2
Artesunate	1	2
Ashwagandha	1	2
Asiatic Acid	1	2
Berries: All	1	2
Bifidobacterium Bifidum	1	2
Bifidobacterium Longum	1	2
Bitter Orange	1	2
Carnosic Acid	1	2
Carotenoids	1	2
Celery Oil	1	2
Chamomile	1	2
Chrysin	1	2
Citrus naringin	1	2
Cucurbitacin B	1	2
EGCG (Epigallocatechin gallate)	1	2
Gardenia	1	2
Grape Seed Extract	1	2
Hyperforin	1	2
Lactobacillus Brevis	1	2
Lavender: Essential Oil	1	2
Lemon Balm	1	2
Ligustrazine	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Lotus	1	2
Lycopene	1	2
Lysergic Acid Diethylamide (LSD)	1	2
Magnolia	1	2
Magnolol	1	2
Nattokinase	1	2
Nobiletin	1	2
Oleuropein	1	2
Omega-3 Fatty Acids	1	2
Paeoniflorin	1	2
Passion Flower	1	2
Prunella vulgaris	1	2
Rose	1	2
Rosmarinic acid	1	2
Royal Jelly	1	2
Safflower	1	2
Saffron	1	2
Sea buckthorn	1	2
Sulforaphane	1	2
Thymol	1	2
Turmeric	1	2
Turmerones	1	2
Vitamin D	1	2
Ayahuasca	1	1
Baicalein	1	1
Cannabis	1	1
Citicoline	1	1
Gotu Kola	1	1
Harmine	1	1
Palmitoylethanolamide	1	1
Poria cocos	1	1
Schisandra	1	1
Sesamin	1	1
Taurine	1	1
Vanillic Acid	1	1
Vitamin A	1	1
Walnut	1	1
Zinc	1	1

[+]

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

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Pubmed Data : Lasers Med Sci. 2019 Oct ;34(8):1619-1625. Epub 2019 Mar 2. PMID: 30826952

Article Published Date : Sep 30, 2019

Study Type : Animal Study

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Diseases : Stroke: Ischemic

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

[+]

A natural carotenoid crocin exerts antidepressant action.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Neural Transm (Vienna). 2020 Jan 23. Epub 2020 Jan 23. PMID: 31974720

Article Published Date : Jan 22, 2020

Study Type : Animal Study

Additional Links

Diseases : Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Antidepressive Agents, Neurogenesis, Neuroprotective Agents

[+]

Aromatic turmerone constitutes a promising candidate to support regeneration in neurologic disease.Dec 31, 2013

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Pubmed Data : Stem Cell Res Ther. 2014 ;5(4):100. Epub 2014 Sep 26. PMID: 25928248

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Combined effect of Cerium oxide nanoparticles loaded scaffold and photobiomodulation therapy on pain and neuronal regeneration following spinal cord injury.Jan 31, 2024

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Pubmed Data : Photochem Photobiol Sci. 2024 Feb ;23(2):225-243. Epub 2024 Feb 1. PMID: 38300466

Article Published Date : Jan 31, 2024

Study Type : Animal Study

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Diseases : Hyperalgesia, Spinal Cord Injuries

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Neurogenesis

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Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation.Oct 31, 2018

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Pubmed Data : Mol Med Rep. 2018 Nov ;18(5):4417-4427. Epub 2018 Sep 4. PMID: 30221704

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Pubmed Data : J Clin Psychopharmacol. 2000 Dec;20(6):680-4. PMID: 18362141

Article Published Date : Dec 01, 2000

Study Type : Animal Study

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Substances : Curcumin

Diseases : Aging, Brain Injury: Hippocampal Damage

Pharmacological Actions : Antiproliferative , Neuritogenic, Neurogenesis

[+]

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Pubmed Data : FASEB J. 2020 Feb 6. Epub 2020 Feb 6. PMID: 32027412

Article Published Date : Feb 05, 2020

Study Type : Animal Study

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Substances : Hydroxytyrosol

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

[+]

Hyperforin promotes post-stroke neuroangiogenesis.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurosci Lett. 2019 05 14 ;701:180-192. Epub 2019 Feb 28. PMID: 30825591

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Pubmed Data : Biol Sport. 2015 Nov ;32(4):295-300. Epub 2015 Aug 4. PMID: 26681831

Article Published Date : Oct 31, 2015

Study Type : Animal Study

Additional Links

Diseases : Alzheimer's Disease

Therapeutic Actions : Exercise

Pharmacological Actions : Neurogenesis

[+]

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.Mar 31, 2019

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Pubmed Data : Neural Plast. 2021 ;2021:5519330. Epub 2021 Sep 6. PMID: 34545285

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Lycopene

Diseases : Alzheimer's Disease

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

[+]

Magnolol exerts antidepressant-like effects on behaviours by enhancing hippocampal neurogenesis.Oct 31, 2016

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Pubmed Data : Phytother Res. 2016 Nov ;30(11):1856-1861. Epub 2016 Aug 11. PMID: 27510271

Article Published Date : Oct 31, 2016

Study Type : Animal Study

Additional Links

Substances : Magnolol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Neurogenesis

[+]

Melatonin improved the depressive behaviour of stressed mice.Jul 10, 2016

Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Jan 10, 2016

Study Type : Animal Study, In Vitro Study

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Substances : Ligustrazine

Diseases : Middle Cerebral Artery Occlusion (MCAO)

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

[+]

The activation of the endocannabinoid system promotes white and gray matter recovery after neonatal HI injury.Nov 30, 2010

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Pubmed Data : Stroke. 2010 Dec ;41(12):2956-64. PMID: 21115947

Article Published Date : Nov 30, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Brain Ischemia, Neonatal Stroke, Stroke: Attenuation/Recovery

Pharmacological Actions : Neurogenesis

Additional Keywords : Endocannabinoid System, Neuro-repair

[+]

The benefits of voluntary physical exercise after traumatic brain injury on rat's object recognition memory.Jan 07, 2020

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Pubmed Data : Exp Neurol. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29056360

Article Published Date : Oct 18, 2017

Study Type : Animal Study

Additional Links

Diseases : Stroke: Ischemic

Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy, Light Therapy, Photobiomodulation

Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis

[+]

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Pubmed Data : Mol Nutr Food Res. 2017 Dec 26. Epub 2017 Dec 26. PMID: 29277983

Article Published Date : Dec 25, 2017

Study Type : Animal Study

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Substances : Thymoquinone

Pharmacological Actions : Neurogenesis

[+]

Treadmill exercise alleviates Alzheimer disease-associated memory loss by increasing neurogenesis.Jul 31, 2016

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Pubmed Data : J Exerc Rehabil. 2016 Aug ;12(4):276-83. Epub 2016 Aug 31. PMID: 27656623

Article Published Date : Jul 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Alzheimer's Disease, Diabetic Complications

Therapeutic Actions : Exercise

Pharmacological Actions : Neurogenesis, Neuroprotective Agents, Wnt/β-catenin signaling pathway modulation

[+]

Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta.Dec 31, 2021

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Pubmed Data : Iran J Basic Med Sci. 2024 ;27(7):914-922. PMID: 38800026

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Crocin

Pharmacological Actions : Neurogenesis

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Effects of Ginkgo biloba extract EGb761 on neural differentiation of stem cells offer new hope for neurological disease treatment.Jun 30, 2019

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Pubmed Data : Neural Regen Res. 2019 Jul ;14(7):1152-1157. PMID: 30804240

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Pubmed Data : Exp Ther Med. 2016 Aug ;12(2):683-689. Epub 2016 Jun 2. PMID: 27446261

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Pubmed Data : Sports Med Open. 2015;1(1):4. Epub 2015 Apr 17. PMID: 26284161

Article Published Date : Dec 31, 2014

Study Type : Review

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Angiogenesis Inducing Agents, Neurogenesis

Additional Keywords : Risk Reduction

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Pubmed Data : CNS Neurol Disord Drug Targets. 2018 ;17(7):547-556. PMID: 29992896

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Panax Notoginseng

Pharmacological Actions : Neurogenesis, Wnt/β-catenin signaling pathway modulation

[+]

This review details the mechanisms of neurodegeneration and highlights the beneficial effects of cannabinoid treatment.Feb 28, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Pharmacol. 2014 Mar ;171(6):1347-60. PMID: 24172185

Article Published Date : Feb 28, 2014

Study Type : Review

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Alzheimer's Disease, Brain Inflammation , Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis, Neuroprotective Agents

[+]

This study demonstrates the positive regulatory role of GBE in NSC proliferation and differentiation into functional neurons in vitro.Mar 30, 2015

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Pubmed Data : Cell Mol Neurobiol. 2015 Mar 31. Epub 2015 Mar 31. PMID: 25822771

View the Evidence: 173 Abstracts with Neurogenesis Research

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Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Alpha-lipoic acid, linoleic acid and echinacea proved to be an effective treatment for controlling symptoms and improving the evolution of carpal tunnel syndrome.May 31, 2015

Indonesian ginger extract promotes neurogenesis of human neural stem cells.Jul 04, 2020

Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells.Sep 19, 2022

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles.Aug 31, 2017

5-MeO-DMT affects neurogenesis and this effect may contribute to the known antidepressant properties of DMT-derived compounds.Dec 31, 2017

904-nm LED irradiation may beneficially affect neurogenesis, muscle resistance, and animal motor behavior following ischemic CVA.Sep 30, 2019

A natural carotenoid crocin exerts antidepressant action.Dec 31, 2022

Administration of THC was observed to enhance the neurogenesis in the brainSep 20, 2017

Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease.Jan 24, 2021

Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway.Jan 22, 2020

Aromatic turmerone constitutes a promising candidate to support regeneration in neurologic disease.Dec 31, 2013

Asiatic acid can enhance spatial memory after administration for 28 days.Oct 04, 2015

Astaxanthin supplementation enhanced adult hippocampal neurogenesis and spatial memory in mice. Dec 07, 2015

Astragaloside IV improves neurobehavior and promotes hippocampal neurogenesis.Jul 15, 2020

Astragaloside IV promotes adult neurogenesis in hippocampal dentate gyrus.Aug 28, 2018

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis.Feb 28, 2021

Astragaloside IV stimulates hippocampal neurogenesis after stroke.Dec 31, 2019

Astragaloside VI could be a new therapeutic drug candidate for post-stroke treatment.Aug 06, 2018

Bacopa monnier ameliorated trimethyltin-induced cognitive disturbances.Dec 31, 2018

Bacopa monnieri extract exerted neuroprotective effects possibly by promoting hippocampal neurogenesis with elevation of BDNF level.Oct 31, 2016

Bacopa monnieri extract improves memory performance.May 08, 2020

Baicalin may promote hippocampal neurogenesis, thereby exerting the antidepressant effect.Jul 31, 2021

Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI promotes neuronal rejuvenation in aged mice.May 06, 2022

Brahmi is a potential cognitive enhancer against schizophrenia.Feb 28, 2015

Chronic administration of thymoquinone enhances adult hippocampal neurogenesis and improves memory.Dec 01, 2021

Chrysin loaded nanovesicles ameliorated diabetic peripheral neuropathy.Apr 24, 2023

Co-delivery of curcumin-resveratrol-carnosic acid complex promotes neurogenesis and cognitive recovery in a rodent model of repeated mild traumatic brain injury.Jan 31, 2025

Combined effect of Cerium oxide nanoparticles loaded scaffold and photobiomodulation therapy on pain and neuronal regeneration following spinal cord injury.Jan 31, 2024

Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation.Oct 31, 2018

Consuming grape seed extract in the elderly can potentially alleviate the age-related reduction of hippocampal neurogenesis and synaptogenesis.May 09, 2021

Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice.Jun 29, 2019

Curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair.Dec 01, 2000

Curcumin may protect from focal cerebral ischemia reperfusion injury as well as stimulate neurogenesis.May 31, 2016

Curcumin nanoparticles may offer a therapeutic approach to treating neurodegenerative diseases by enhancing brain self-repair mechanisms.Jan 27, 2014

Curcumin provides neuroprotection against BPA-mediated impaired neurogenesis via activation of the Wnt/β-catenin signaling pathway.May 11, 2015

Dietary heat-killed Lactobacillus brevis SBC8803 functions as memory and neurogenesis enhancers.May 31, 2019

DL-3-n-butylphthalide promotes hippocampal neurogenesis and reduces mossy fiber sprouting in chronic temporal lobe epilepsy.Jan 02, 2022

Effect of 2-week naringin supplementation on neurogenesis and BDNF levels in ischemia-reperfusion model.Mar 07, 2024

EGCG could have beneficial effects on neurogenesis and stroke recovery. May 19, 2016

Electroacupuncture alleviates SD-induced spatial memory impairment.Oct 07, 2021

Electroacupuncture attenuates depressive-like behaviors in poststroke depression.Oct 01, 2024

Erinacine A and S reduce Alzheimer’s disease pathology via reducing amyloid deposition and promoting neurogenesis.Feb 16, 2018

Exercise delays cognitive decline by the enhancing neurogenesis and increasing BDNF expression in the context of vascular dementia.Mar 31, 2016

Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats.Apr 23, 2024

Exercise serves as a potential strategy to prevent the development of Alzheimer's disease by regulating adult neurogenesis and brain immune-activity.May 01, 2018

G. lucidum polysaccharides could serve as a regenerative agent for the treatment of cognitive decline associated with neurodegenerative diseases.Jan 09, 2017

Gastrodin improves hippocampal neurogenesis by NO-cGMP-PKG signaling pathway in cerebral ischemic mice.Nov 30, 2019

Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.Aug 18, 2021

Gastrodin treatment markedly preserved the Wnt/β-Catenin signalling pathway, which could promote neurogenesis and provide neuroprotection brain injury.May 31, 2019

Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury.Mar 21, 2023

Harmine produces antidepressant-like effects via restoration of astrocytic functions.Oct 02, 2017

Hesperidin alleviates methotrexate-induced memory deficits via hippocampal neurogenesis in adult rats.Apr 24, 2019

Hydroxytyrosol stimulates neurogenesis in aged dentate gyrus by enhancing stem and progenitor cell proliferation and neuron survival.Feb 05, 2020

Hyperforin promotes post-stroke neuroangiogenesis.Dec 31, 2018

Improvement in neurogenesis and memory function by administration of Passiflora incarnata extract.Apr 01, 2019

Korean red ginseng promotes hippocampal neurogenesis in mice.Apr 30, 2020

Lavender essential oil ameliorates depression-like behavior and increases neurogenesis and dendritic complexity in rats.Jan 13, 2019

Leptin combined with withaferin A boost posthemorrhagic neurogenesis.Jun 30, 2024

Long-term administration of salvianolic acid A promotes endogenous neurogenesis in ischemic stroke.Feb 24, 2022

Long-term treadmill exercise could improve the spatial memory of the male APPswe/PS1dE9 AD mice.Oct 31, 2015

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.Mar 31, 2019

Luteolin promotes neuronogenesis in hippocampus of chronic unpredictable mild stress rats and primary hippocampus of fetal rats.Jul 31, 2024

Luteolin treatment ameliorates brain development and behavioral performance in a mouse model of CDKL5 deficiency disorder.Aug 04, 2022

Lycopene-loaded microemulsion attenuates cognitive impairment in Aβ-induced AD rats by promoting neurogenesis.Dec 31, 2020

Magnolol exerts antidepressant-like effects on behaviours by enhancing hippocampal neurogenesis.Oct 31, 2016

Melatonin improved the depressive behaviour of stressed mice.Jul 10, 2016

Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a model of Alzheimer's disease.Aug 31, 2019

Metabolomics reveals the effects of hydroxysafflor yellow A on neurogenesis and axon regeneration after experimental traumatic brain injury.Nov 30, 2023

Moringa oleifera seed extract protects against brain damage in both the acute and delayed stages of ischemic stroke.Jul 14, 2019

N. nucifera extract is the potential neuroprotective and memory enhancing agent. Dec 31, 2015

Nattokinase promotes post-stroke neurogenesis and cognition recovery.Aug 01, 2023

Neurogenesis

View the Evidence:
173 Abstracts with Neurogenesis Research