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NF-kappaB Inhibitor
Views 3617
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535 Substances Researched for NF-kappaB Inhibitor
Name
AC
CK
Focus
Curcumin
267
390
Flavonoids
52
92
Resveratrol
54
91
Ginsenosides
51
81
Polyphenols
28
55
Puerarin
25
55
Paeoniflorin
33
53
Thymoquinone
32
50
Astaxanthin
21
45
Berberine
28
41
Genistein
18
41
Parthenolide
27
41
Apigenin
16
35
Anthocyanins
20
34
Ginger
15
34
Sulforaphane
25
34
Vitamin C
19
33
Melatonin
20
32
Paeonol
18
32
Tanshinone IIA
21
32
Vitamin D
17
30
Pomegranate
11
29
Hesperidin
11
28
Fisetin
15
26
Quercetin
16
25
Caffeic acid phenethyl ester
12
24
EGCG (Epigallocatechin gallate)
18
24
Green Tea
10
24
Licorice
17
24
Asiatic Acid
13
23
Isoliquiritigenin
12
22
Chrysin
14
21
Garlic
9
21
Naringenin
11
21
Nobiletin
12
21
Astragaloside
12
20
Blueberry
10
20
Fucoidan
13
20
Luteolin
11
20
Olive Oil
6
20
Lycopene
11
19
Phloretin
10
19
Pterostilbene
11
19
Stilbenes
12
19
Silibinin
6
18
Diosgenin
9
17
Lychee
8
17
Xanthohumol
12
17
Bee Venom
9
16
Cannabidiol
10
16
Crocin
10
16
Ligustrazine
10
16
Mangiferin
11
16
Black Tea
5
15
Lotus
11
15
Rosmarinic acid
6
15
Deguelin
8
14
Dogwood
9
14
Ellagic Acid
10
14
Isoflavones
3
14
Kaempferol
8
14
Lactobacillus fermentum
3
14
Peony
10
14
Piceatannol
10
14
Alpha-Lipoic Acid
7
13
Bilberry
3
13
Carnosine
3
13
Dandelion
10
13
Emodin
8
13
Gingerol
8
13
Piperine
8
13
Purslane
4
13
Pycnogenol (Pine Bark)
3
13
Rose
9
13
Strawberry
4
13
Wogonin
9
13
Black Raspberry
2
12
Carnosic Acid
7
12
Chaga Mushroom (Inonotus obliquus)
8
12
Ginseng (Korean)
7
12
Isothiocyanates
8
12
Nigella sativa (aka Black Seed)
3
12
Piperlongumine
8
12
Punicalagin
9
12
Safflower
8
12
Ursolic Acid
10
12
Vitamin E: alpha tocopherol
5
12
Formononetin
6
11
Ginkgo biloba
6
11
Lactobacillus Acidophilus
2
11
Medicinal Mushrooms
7
11
Moringa oleifera
8
11
Phellinus Linteus
8
11
Shikonin
8
11
Ashwagandha
6
10
Bamboo
6
10
Biochanin A
6
10
Diosmin
6
10
Fruit: All
1
10
Gastrodin
6
10
Geraniol
5
10
Grape Seed Extract
6
10
Honokiol
6
10
Hydroxytyrosol
6
10
Lactobacillus delbrueckii Subsp
1
10
Myricetin
7
10
Patchouli
7
10
Prunella vulgaris
5
10
Selenium
6
10
Tocotrienols
1
10
Turmeric
8
10
Yoghurt
1
10
Zyflamend
1
10
6-Shogaol
7
9
Astragalus
3
9
Bee Propolis
5
9
Eriodictyol
5
9
NAC (N-acetyl-L-cysteine)
6
9
Oridonin
8
9
Reishi Mushroom
5
9
Sweet Potato: Purple
5
9
Tangeretin
6
9
Vitamin E
6
9
Vitexins
5
9
Acai
3
8
Allicin
5
8
Angelica
3
8
Cardamonin
5
8
Citral
3
8
Citrus naringin
5
8
Fermented Foods and Beverages
5
8
Ferulic acid
5
8
Fucoxanthin
5
8
Garlic: Aged
3
8
Grape
6
8
Indole-3-Carbinol
5
8
Lactobacillus rhamnosus GG
3
8
Magnolol
5
8
Nexrutine (Phellodendrom)
4
8
Oleuropein
5
8
Palmitoylethanolamide
4
8
Poria cocos
5
8
Rooibos
4
8
Zerumbone
5
8
Aloe Vera
4
7
Arctigenin
5
7
Artesunate
5
7
Barley
2
7
Betulinic acid
6
7
Carnosol
4
7
Chinese Skullcap
4
7
Chrysanthemum Indicum
5
7
Crocetin
4
7
Echinacea
3
7
Flaxseed
4
7
Goji
4
7
Guduchi
2
7
Helenalin
6
7
Honey
5
7
Honeysuckle
5
7
Lutein
4
7
Rosemaric Acid
4
7
Rutin
4
7
Verbascoside
5
7
Arginine
3
6
Arnica
6
6
Artemisinin
5
6
Bifidobacterium Longum
3
6
Capsaicin
5
6
Chokeberry
4
6
Cinnamaldehyde
4
6
Cordyceps Militaris
4
6
DHA (Docosahexaenoic Acid)
3
6
Diosmetin
3
6
EPA (Eicosapentaenoic Acid)
3
6
Ginseng
4
6
Ginseng (Siberian)
3
6
Glycyrrhizin
6
6
Hydrogen Water
3
6
Kimchi
4
6
Lactobacillus plantarum
3
6
Lactoferrin
4
6
Lion's Mane (Hericium Erinaceus)
4
6
Liquiritigenin
4
6
Noni
4
6
Oleanolic acid
4
6
Oleocanthal
2
6
Oligonol
4
6
Omega-3 Fatty Acids
4
6
Sesamin
4
6
Sesamol
4
6
Triptolide
4
6
Apples
3
5
Baicalein
4
5
Berbamine
4
5
Beta-Caryophyllene
4
5
Blackberry
3
5
Bromelain
5
5
Carotenoids
4
5
Carvacrol
3
5
Catechin
5
5
Celastrol
3
5
Corn Silk
3
5
Cryptoxanthin
3
5
Curcumol
5
5
Daidzein
3
5
Diallyl sulfide
3
5
Feverfew
5
5
Gynostemma
3
5
Kiwifruit
3
5
Lupeol
4
5
Magnesium
3
5
Mulberry
4
5
Parsley
1
5
Persimmon
4
5
Phenethyl isothiocyanate
4
5
Royal Jelly
3
5
Tocotrienol: Delta
3
5
Toona sinensis
3
5
Vitamin K2
4
5
Wasabi
3
5
Arugula
2
4
Babchi
3
4
Burdock
3
4
Cordyceps sinensis
2
4
Cyanidin
3
4
Damnacanthal
3
4
Delphinidin
2
4
Fig
2
4
Folic Acid
2
4
Frankincense
4
4
Gotu Kola
2
4
Lactobacillus sakei
2
4
Lignans
4
4
Loquat
3
4
Magnolia
3
4
Oats
3
4
Olive
3
4
Olive leaf extract
3
4
Panax Notoginseng
3
4
Perilla
2
4
Rice
2
4
Rosemary
3
4
Sea buckthorn
2
4
Spikenard
3
4
Tannic Acid
2
4
Tart Cherry
2
4
Theanine
2
4
Thymol
2
4
Tomato
3
4
Tripterygium wilfordii
3
4
Vitamin K
3
4
Walnut
2
4
White Tea
2
4
Zinc
3
4
Acacia catechu
2
3
Adlay
3
3
Amla Fruit
2
3
Andrographolide
2
3
Apple Polyphenols
2
3
Avocado
2
3
Bergamot orange
2
3
Beta Sitosterol
2
3
Bisdemethoxycurcumin
3
3
Bitter Melon
2
3
Bitter Orange
3
3
Broccoli Sprouts
3
3
Bufalin
2
3
Caffeic Acid
2
3
Cannabis
2
3
Chlorogenic Acid
2
3
Chlorophyllin
2
3
Coenzyme Q10
2
3
D-Limonene
2
3
Demethoxycurcumin
3
3
Ginseng (American)
2
3
Guava
2
3
Hemp Seed
3
3
Hyperforin
3
3
Krill
2
3
Lavender: Essential Oil
2
3
Lingonberry
2
3
Myrrh
2
3
Neem
2
3
Oligosaccharides
2
3
Palm Oil
2
3
Phyllanthus amarus
3
3
Probiotics
2
3
Procyanidin B2
3
3
Raspberry
2
3
Schisandra
3
3
Seaweed: Brown
3
3
Silymarin
2
3
Soy
2
3
Theaflavins
2
3
Thistle
3
3
Tocotrienol: Gamma
2
3
Vanillin
2
3
Vitamin E: Gamma-Tocopherol
2
3
Vitamin E: Gamma-tocotrienol
3
3
White Mulberry
2
3
acetyl-11-keto-beta-boswellic acid
2
3
2-Methoxyestradiol
1
2
4-Shogaol
2
2
Amygdalin (laetrile)
2
2
Anemarrhena asphodeloides
1
2
Antrodia Camphorate
1
2
Apocynin
1
2
Apple
1
2
Apricot
1
2
Bai Zhu
1
2
Banana Stem
1
2
Barberry
1
2
Basil
1
2
Bee Pollen
1
2
Betaine
1
2
Black Currant
1
2
Black Pepper
2
2
Camel Milk
1
2
Cat's Claw
2
2
Cinnamon
1
2
Citrus Peel
1
2
Coffee
1
2
Coptis chinensis
1
2
Coriandrum sativum
1
2
Corn: Purple
1
2
Cranberry
1
2
Cucurbitacin B
1
2
Cucurbitacin E
2
2
Curcumin: Degradiation byproducts
2
2
Cyanidin 3-glucoside
2
2
Dill
1
2
Dopa bean
1
2
Epimedium
1
2
Eucalyptus
2
2
Eugenol
2
2
Fennel
1
2
Fish Oil
1
2
Flavan-3-ols
1
2
Flaxseed Oil
1
2
Galactooligosaccharides
1
2
Garcinia Mangostana
1
2
Gardenia
1
2
Glucosamine
1
2
Glycyrrhiza glabra
1
2
Gold (nanoparticles)
1
2
Grapefruit
1
2
Hibiscus
2
2
Hibiscus sabdariffa
1
2
Histidine
1
2
Holy Basil
1
2
Huperzine
2
2
Hyssop
1
2
Isoquercitrin
1
2
Kaempferia parviflora
1
2
Kefir
1
2
Kudzu
1
2
L-arginine
1
2
Lemon Balm
1
2
Lemongrass
1
2
Lentinan
1
2
Litchi
1
2
Lithospermum erythrorhizon
2
2
Long Pepper
1
2
Maca
1
2
Mango leaf
1
2
Manuka Honey
1
2
Marjoram
2
2
Medium Chain Triglycerides
1
2
Milk Thistle
1
2
Mint
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Mung Bean
1
2
Niacin
1
2
Nordihydroguaiaretic acid (NDGA)
1
2
Okra
1
2
Orange: Mandarin
1
2
Orthosiphon
1
2
Papaya
2
2
Peach
1
2
Pelargonium sidoides
1
2
Phyllanthus emblica
1
2
Pine Bark Extract
2
2
Pineapple
1
2
Plantago asiatica
1
2
Potato
1
2
Potato: Pigmented
1
2
Propolis: Brazillian
1
2
Psychedelics:All
2
2
Raspberry ketone
1
2
Red Sage
1
2
Rhubarb
2
2
Rubia Cordifolia
1
2
Saccharomyces Boulardii
1
2
Safranal
1
2
Saikosaponin
1
2
Salvia miltiorrhiza
1
2
Saturated fatty acids
1
2
Seaweed
1
2
Shiitake Mushroom
1
2
Sinomenine
1
2
Soy: Fermented
1
2
Soybean: Black
1
2
Stigmasterol
1
2
Sweet Potato
1
2
Tetrahydrocurcumin
1
2
Tongkat Ali
1
2
Triphala
1
2
Vinegar
1
2
Vitamin B-12
1
2
Vitamin B-6
1
2
Vitamin E: delta-tocopherol
1
2
Vitex negundo
1
2
Watermelon
1
2
White Pepper
1
2
Xanthones
1
2
Yarrow
1
2
Zeaxanthin
1
2
neohesperidin
1
2
Acorus calamus
1
1
Aduki bean
1
1
Andrographis
1
1
Antrodia camphorata
1
1
Apple Pectin
1
1
Artichoke
1
1
Ayahuasca
1
1
Bael
1
1
Bay leaf
1
1
Benzyl isothiocyanate
1
1
Berries: All
1
1
Beta-Elemene
1
1
Beta-glucan
1
1
Boswellia
1
1
Broccoli
1
1
Cafestol
1
1
Caffeoylquinic Acids
1
1
Capparis spinosa (caper)
1
1
Carrot
1
1
Cashew
1
1
Catechols
1
1
Celery
1
1
Chickpea
1
1
Chicoric Acid
1
1
Chicory
1
1
Chitosan
1
1
Chlorella (Algae)
1
1
Coconut
1
1
Comfrey
1
1
Copper
1
1
Coriolus versicolor
1
1
Cucurbitacin D
1
1
Cumin
1
1
Curcumin: Lipidated
1
1
Daisy
1
1
Delta-tetrahydrocannabinol (THC)
1
1
Dibenzoylmethane (DBM)
1
1
Epicatechin
1
1
Feijoa
1
1
Flowers
1
1
Gallic Acid
1
1
Garcinia indica
1
1
Genipin
1
1
Guggul
1
1
Haritaki (Terminalia chebula)
1
1
Hibiscus rosa-sinensis
1
1
Hirudin (from Medicinal Leaches)
1
1
Hops
1
1
Horsetail
1
1
Houttuynia cordata
1
1
Huaier (Trametes robiniophila murr)
1
1
Hyaluronic Acid
1
1
Hydrangea
1
1
Japanese mugwort
1
1
Jujube
1
1
Justicia gendarussa
1
1
Kahweol
1
1
Kava Kava
1
1
Lactobacillus paracasei
1
1
Lactobacillus reuteri
1
1
Lactobacillus rhamnosus
1
1
Linoleic acid
1
1
Loquat Leaves
1
1
Lysine
1
1
Maitake Mushroom
1
1
Mangosteen
1
1
Matairesinol
1
1
Methylchlorogenic acid
1
1
Motherwort
1
1
Mushrooms: All
1
1
Nicotinamide
1
1
Nutmeg
1
1
Oak
1
1
Octacosanol
1
1
Onion
1
1
P-Coumaric Acid
1
1
Pachymic acid
1
1
Papain
1
1
Passion Flower
1
1
Phyllanthus niruri (Stonebreaker)
1
1
Phyllanthus urinaria
1
1
Pine Cone
1
1
Plum
1
1
Polyunsaturated Fatty Acids (PUFAs)
1
1
Potassium
1
1
Prickly Pear Cactus
1
1
Proanthocyanidins
1
1
Psyllium
1
1
Pumpkin
1
1
Quince
1
1
Raisins
1
1
Red Clover
1
1
Red Marine Algae
1
1
Red Wine Extract
1
1
Rice Bran
1
1
Rice: Black
1
1
Saffron
1
1
Sesame Seeds
1
1
Sessile Joyweed
1
1
Silver (nanoparticles)
1
1
Sophora Flavescens
1
1
St. Johns Wort
1
1
Sumac
1
1
Syrian rue
1
1
Tansy
1
1
Taurine
1
1
Thyme
1
1
Toad
1
1
Tomatidine
1
1
Tribulus
1
1
Turmerones
1
1
Tyrosol
1
1
Unsaponifiables
1
1
Vitamin K2: Menaquinone-7
1
1
Willow Bark
1
1
cottonseed oil (gossypol)
1
1
Research Articles
2098
Cumulative Knowledge Score
3394
Overall Research Rating
EXCELLENT
View the Evidence:
2241 Abstracts with NF-kappaB Inhibitor Research
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[+]
Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.
Dec 04, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Dec 5 ;6:37819. Epub 2016 Dec 5. PMID:
27917862
Article Published Date
: Dec 04, 2016
Study Type
: Human Study
Additional Links
Substances
:
Purslane
Diseases
:
Atherosclerosis
,
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
NF-kappaB Inhibitor
,
Uricosuric Agents
Additional Keywords
:
Risk Reduction
[+]
Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Biol Toxicol. 2010 Oct;26(5):457-67. Epub 2010 Mar 14. PMID:
20229275
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Immune Disorders: Low Immune Function
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Apoptotic
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.
Dec 06, 2006
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID:
16824715
Article Published Date
: Dec 06, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Jun ;44:204-209. Epub 2019 Apr 22. PMID:
31126557
Article Published Date
: May 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Invest Dermatol. 2010 Aug;130(8):2110-9. Epub 2010 Apr 15. PMID:
20393484
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
T-Cell Lymphoma: Cutaneous
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2012 Jan ;5(1):41-50. Epub 2011 Dec 1. PMID:
22135048
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
,
Risk Reduction
[+]
French maritime pine bark extract (Pycnogenol) displays anti-inflammatory effects in vivo.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Inflamm (Lond). 2006;3:1. Epub 2006 Jan 27. PMID:
16441890
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Inflammation
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Fruit and vegetable juice concentrate may be beneficial for improving the metabolic profile in obese individuals.
Feb 07, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Feb 8 ;9(2). Epub 2017 Feb 8. PMID:
28208713
Article Published Date
: Feb 07, 2017
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
Diseases
:
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Risk Reduction
[+]
Genistein and puerarin could inhibit the pathway of NF-kappaB and TNF-alpha in asthma patients.
Jan 31, 2010
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2010 Feb ;65(2):127-31. PMID:
20225658
Article Published Date
: Jan 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Puerarin
Diseases
:
Asthma
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vasodilator Agents
[+]
Ginger can improve rheumatoid arthritis by decreasing disease manifestations in patients.
May 24, 2019
Click here to read the entire abstract
Pubmed Data
: Gene. 2019 May 25 ;698:179-185. Epub 2019 Mar 4. PMID:
30844477
Article Published Date
: May 24, 2019
Study Type
: Human Study
Additional Links
Substances
:
Ginger
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Gene Expression Regulation
,
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rd is efficacious against acute ischemic stroke.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2016 May ;53(4):2529-40. Epub 2015 Jun 17. PMID:
26081140
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Green tea induced changes in NFκB and systemic oxidation, and uptake of GT polyphenols in prostate tissue they may have a role in prostate cancer prevention and treatment.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Prostate. 2015 Apr 1 ;75(5):550-9. Epub 2014 Dec 24. PMID:
25545744
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Green Tea
,
Polyphenols
Diseases
:
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Jul 1. Epub 2019 Jul 1. PMID:
31264313
Article Published Date
: Jun 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults.
Jan 21, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 07 22 ;10(1):12130. Epub 2020 Jul 22. PMID:
32699287
Article Published Date
: Jan 21, 2020
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Hyperbaric oxygen therapy regulated the inflammatory reaction in secondary spinal cord injury.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2018 Nov 1 ;692:47-52. Epub 2018 Nov 1. PMID:
30391318
Article Published Date
: Oct 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Spinal Cord Injuries
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Inflammatory markers response to crocin supplementation in patients with type 2 diabetes mellitus.
Apr 14, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Apr 15. Epub 2021 Apr 15. PMID:
33856733
Article Published Date
: Apr 14, 2021
Study Type
: Human Study
Additional Links
Substances
:
Crocin
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
L-carnosine protects against oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.
Feb 14, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2019 Feb 15 ;365:41-50. Epub 2018 Dec 25. PMID:
30592963
Article Published Date
: Feb 14, 2019
Study Type
: Human Study
Additional Links
Substances
:
Carnosine
Diseases
:
Chemotherapy-Induced Toxicity: Oxaliplatin
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.
Feb 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2016 Feb 28 ;115(4):567-75. Epub 2016 Jan 15. PMID:
26769562
Article Published Date
: Feb 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus Acidophilus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interferon Gamma Reducer
,
Interleukin-10 upregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Low-fat yogurt for 9 weeks reduced biomarkers of chronic inflammation and endotoxin exposure in premenopausal women.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2017 Dec ;118(12):1043-1051. Epub 2017 Nov 28. PMID:
29179781
Article Published Date
: Nov 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
C-Reactive Protein
,
Endotoxemia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Lyophilized black raspberries significantly decreased urinary lipid peroxidation levels and significantly increased GST-pi, a marker of detoxification.
Jul 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jul 7. Epub 2016 Jul 7. PMID:
27409421
Article Published Date
: Jul 06, 2016
Study Type
: Human Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Barrett Esophagus
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
[+]
Olive oil consumption has an ameliorative effect in non-alcoholic fatty liver disease.
Apr 21, 2009
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2009 Apr 21;15(15):1809-15. PMID:
19370776
Article Published Date
: Apr 21, 2009
Study Type
: Human Study
Additional Links
Substances
:
Olive Oil
Diseases
:
Fatty Liver
,
Insulin Resistance
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
,
Glucagon Like peptide 1 (GLP-1) Up-regulation
,
Glucose transporter-2 (GLUT2) expression up-regulation
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Oral supplementation with probiotics could be helpful in maintaining remission and preventing relapse of ulcerative colitis.
Sep 06, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2010 Sep 7 ;16(33):4145-51. PMID:
20806430
Article Published Date
: Sep 06, 2010
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus delbrueckii Subsp
,
Lactobacillus fermentum
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate juice increases sirtuin1 protein in peripheral blood mononuclear cell from patients with type 2 diabetes.
Jun 28, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Syndr Relat Disord. 2018 Jun 29. Epub 2018 Jun 29. PMID:
29957104
Article Published Date
: Jun 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.
Jul 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2010 Aug ;107(2):637-42. Epub 2010 Mar 22. PMID:
20346059
Article Published Date
: Jul 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones
Diseases
:
Angina Pectoris
,
Atherosclerosis
,
C-Reactive Protein
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats.
Jan 01, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0174542. Epub 2017 Mar 28. PMID:
28350848
Article Published Date
: Jan 01, 2017
Study Type
: Human Study
Additional Links
Substances
:
Tocotrienols
Diseases
:
Cataract
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.
Mar 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Mar 28. Epub 2016 Mar 28. PMID:
27035424
Article Published Date
: Mar 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Resveratrol
Diseases
:
Chronic Obstructive Pulmonary Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol could be a potential therapeutic target for intrahepatic cholestasis of pregnancy.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Hepatol Res. 2018 Jun 1. Epub 2018 Jun 1. PMID:
29855113
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Cholestasis
,
Pregnancy Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia.
Apr 18, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Apr 19 ;24(8). Epub 2019 Apr 19. PMID:
31010153
Article Published Date
: Apr 18, 2019
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Pre-Eclampsia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sudharshan kriya pranayama can significantly decrease periodontal inflammation and improve periodontal status.
Feb 05, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2020 Feb 6 ;12(2):e6905. Epub 2020 Feb 6. PMID:
32064220
Article Published Date
: Feb 05, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Periodontitis
Therapeutic Actions
:
Therapeutic Breathing
,
Yogic Breathing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
The inhibitory effects of curcumin support its utility as a prophylactic and therapeutic agent for inflammatory bone diseases such as periodontitis.
Jul 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharm Bioallied Sci. 2015 Aug ;7(Suppl 2):S554-8. PMID:
26538916
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Dental Plaque
,
Periodontitis
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Thoughts modulate the expression of inflammatory genes and may improve the coronary blood flow in patients after a myocardial infarction.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2018 Jan ;8(1):150-163. Epub 2017 May 29. PMID:
29322004
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Myocardial Infarction
Therapeutic Actions
:
Meditation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Three months treatment with curcumin in chronic kidney disease patients undergoing hemodialysis resulted in decreased markers of inflammation.
Mar 12, 2020
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2020 Mar 13. Epub 2020 Mar 13. PMID:
32204978
Article Published Date
: Mar 12, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Zyflamend (a multi-herbal formula) has significant therapeutic activity in treating high-grade prostatic intraepithelial neoplasia.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Soc Integr Oncol. 2009 Spring;7(2):43-51. PMID:
19476738
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Zyflamend
Diseases
:
Elevated CRP
,
Prostate: PSA Doubling
,
Prostatic intraepithelial neoplasia (PIN)
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
A Polyphenol-rich pomegranate fruit extract suppresses NF-κB and IL-6 expression.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28276100
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chondroprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2011 Oct ;49(10):2580-5. Epub 2011 Jul 13. PMID:
21771629
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Ammi visnaga, parsley, barley, and camel's grass all display renoprotective effects.
Jun 25, 2019
Click here to read the entire abstract
Pubmed Data
: BMC Complement Altern Med. 2019 Jun 25 ;19(1):149. Epub 2019 Jun 25. PMID:
31238921
Article Published Date
: Jun 25, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Barley
,
Parsley
Diseases
:
Nephrotoxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Angelica and Astragalus could protect against oxidative stress-induced apoptosis in kidney epithelium.
Feb 16, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Feb 17 ;179:412-9. Epub 2015 Dec 21. PMID:
26719285
Article Published Date
: Feb 16, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Angelica
,
Astragalus
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Anthocyanins from wild blueberry reduce the activation of NF-kB and mitigate IL-1B activity human intestinal cells.
Aug 20, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2014 Aug 20 ;62(33):8346-51. Epub 2014 Aug 8. PMID:
25075866
Article Published Date
: Aug 20, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Anthocyanins
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Antioxidant mixtures could prevent the harmful effects of ozone induced oxidative stress in human keratinocytes.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(8):e0131097. Epub 2015 Aug 13. PMID:
26270818
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Phloretin
,
Vitamin C
,
Vitamin E: alpha tocopherol
Diseases
:
Air Pollution Linked Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
Problem Substances
:
Air Pollution: Ozone
[+]
Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.
Aug 24, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Aug 25. Epub 2016 Aug 25. PMID:
27569589
Article Published Date
: Aug 24, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Prostate Cancer
,
Prostate Cancer Stem Cells
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.
Nov 06, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Nov 7. Epub 2016 Aug 7. PMID:
27832944
Article Published Date
: Nov 06, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.
Dec 10, 2015
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID:
26658749
Article Published Date
: Dec 10, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Citral
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Combination treatments with luteolin and fisetin may be a potential candidate for the treatment and prevention of diabetes and its complications.
Jun 25, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Jun 26. Epub 2017 Jun 26. PMID:
28650731
Article Published Date
: Jun 25, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Fisetin
,
Luteolin
Diseases
:
Diabetic Complications
,
Hyperglycemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
[+]
Curcumin might prevent early bacterial or virus infection into the lumen of the intestine or reduce the degree of the infection by inhibiting the inflammatory response.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2015 Apr ;9(2):117-22. Epub 2015 Mar 6. PMID:
25861416
Article Published Date
: Mar 31, 2015
Study Type
: Human In Vitro, In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cholera
,
Gastrointestinal Infections
,
Inflammation
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
Antiviral Agents
,
NF-kappaB Inhibitor
[+]
Diallyl disulfide could be a promising anticancer agent for anti-metastatic treatment of esophageal-gastric junction adenocarcinoma in the future.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2018 Feb ;39(2):784-794. Epub 2017 Nov 27. PMID:
29207122
Article Published Date
: Jan 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
NF-kappaB Inhibitor
[+]
Ecklonia cava extract exerts anti-inflammatory effect in human gingival fibroblasts and chronic periodontitis animal model.
Jul 16, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2021 Jul 17 ;10(7). Epub 2021 Jul 17. PMID:
34359526
Article Published Date
: Jul 16, 2021
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Seaweed: Brown
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Elderflower inhibits all pro-inflammatory activities of major periodontal pathogens.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2006 Feb ;77(2):271-9. PMID:
16460254
Article Published Date
: Feb 01, 2006
Study Type
: Human In Vitro
Additional Links
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Epigenetic upregulation of metallothionein 2A by diallyl trisulfide enhances chemosensitivity of human gastric cancer cells to docetaxel.
Jan 21, 2016
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2016 Jan 22. Epub 2016 Jan 22. PMID:
26801633
Article Published Date
: Jan 21, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemosensitizer
,
NF-kappaB Inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Docetaxel
,
Epigenetic Modification In Cancer
[+]
Lactobacillus rhamnosus GG conditioned medium prevents E. coli meningitis by inhibiting nuclear factor-κB pathway.
Jan 19, 2017
Click here to read the entire abstract
Pubmed Data
: Nan Fang Yi Ke Da Xue Xue Bao. 2017 Jan 20 ;37(1):24-29. PMID:
28109094
Article Published Date
: Jan 19, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Lactobacillus rhamnosus GG
Diseases
:
Escherichia coli Infections
,
Meningitis: Bacterial
Pharmacological Actions
:
Anti-Bacterial Agents
,
NF-kappaB Inhibitor
[+]
Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID:
22348531
Article Published Date
: Aug 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Nexrutine as an agent to potentiate the therapeutic response of docetaxel by suppressing activation of c-FLIP and its upstream regulators.
May 08, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2017 May 9. Epub 2017 May 9. PMID:
28485511
Article Published Date
: May 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Nexrutine (Phellodendrom)
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
NF-kappaB Inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Docetaxel
[+]
Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(6):2414-2426. Epub 2018 Sep 27. PMID:
30261513
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleocanthal
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oligonol suppresses inflammatory cytokine production from human monocytes.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Hum Immunol. 2016 Jun ;77(6):512-5. Epub 2016 Apr 11. PMID:
27079270
Article Published Date
: May 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Lychee
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Olive oil compounds inhibit the effect of the chronic inflammatory microenvironment on glioblastoma progression.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Sep 1. Epub 2015 Sep 1. PMID:
26410343
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Olive Oil
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Parthenolide may be a promising component for bone regeneration in periodontitis treatment.
Aug 21, 2017
Click here to read the entire abstract
Pubmed Data
: J Interferon Cytokine Res. 2017 Aug 22. Epub 2017 Aug 22. PMID:
28829282
Article Published Date
: Aug 21, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Parthenolide
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Bone Regeneration
[+]
Prunella vulgaris attenuates diabetic renal injury.
Mar 29, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2017 Mar 30:1-21. Epub 2017 Mar 30. PMID:
28359196
Article Published Date
: Mar 29, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Prunella vulgaris
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Puerarin possessed certain anticoagulation and may be a potential novel therapeutic drug for thrombosis in coronary artery disease.
Dec 14, 2017
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2017 Dec 15 ;191:115-121. Epub 2017 Oct 14. PMID:
29037842
Article Published Date
: Dec 14, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Puerarin
Diseases
:
Cholesterol: Oxidation
,
Coronary Artery Disease
,
Thrombosis
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Rosmarinic acid may be a potential candidate for the treatment of psoriasis.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jun 15 ;155:189-94. Epub 2016 May 17. PMID:
27210890
Article Published Date
: Jun 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
T. cordifolia dry leaf extracts possess antioxidant and anti-inflammatory properties.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Aug ;61:152831. Epub 2019 Jan 10. PMID:
31035042
Article Published Date
: Jul 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Guduchi
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
These data suggest that nobiletin might be a potential antithrombotic agent of dietary origin.
Mar 14, 2017
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2017 Mar 15 ;128:26-33. Epub 2016 Dec 23. PMID:
28017776
Article Published Date
: Mar 14, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Nobiletin
Diseases
:
Cholesterol: Oxidation
,
Oxidative Stress
Pharmacological Actions
:
Antithrombotic
,
Cardiovascular Agents
,
NF-kappaB Inhibitor
[+]
These results indicate the potential for açai polyphenolics in the prevention of intestinal inflammation.
Oct 06, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Oct 7 ;6(10):3249-56. PMID:
26243669
Article Published Date
: Oct 06, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Acai
Diseases
:
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
These results suggest deguelin could have potential for the treatment of human CLL.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(4):e0154159. Epub 2016 Apr 21. PMID:
27101369
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Deguelin
Diseases
:
Chronic Lymphocytic Leukemia
Pharmacological Actions
:
Apoptotic
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
These results suggest that apamin has therapeutic effect on atopic dermatitis through improvement of inflammatory condition.
Apr 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacol Rep. 2017 Apr 18. Epub 2017 Apr 18. PMID:
28958612
Article Published Date
: Apr 17, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Bee Venom
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
These results suggest that HEABG may be effective in the prevention and treatment of endometriosis in humans.
Jun 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2013 Jul ;32(1):67-78. Epub 2013 Apr 25. PMID:
23619991
Article Published Date
: Jun 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Endometriosis
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Plant Extracts
[+]
These results suggests the possible use of apigenin as a chronic rhinosinusitis therapeutic agent which can suppress tissue remodelling in nasal mucosa.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2018 ;13(8):e0201595. Epub 2018 Aug 30. PMID:
30161164
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Rhinosinusitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
This study demonstrates that sulforaphane targets multiple signaling pathways to suppress ovarian cancer in vitro and in vivo.
Nov 01, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2018 Nov ;42(5):2447-2458. Epub 2018 Sep 6. PMID:
30226534
Article Published Date
: Nov 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Female
,
Ovarian Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
HER-2 oncoprotein down-regulation
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Drug Synergy
,
Isothiocyanates
[+]
Thymoquinone inhibited IL-1β-induced inflammatory mediator production by inhibition of NF-κB and MAPKs signaling pathways in osteoarthritis chondrocytes.
Jul 08, 2015
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2015 Jul 9. Epub 2015 Jul 9. PMID:
26156811
Article Published Date
: Jul 08, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Thymoquinone
Diseases
:
Inflammation
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Triterpene ganoderic acid inhibited production of TNF-α and other proinflammatory cytokines by PBMCs and inflamed CD colonic mucosa due to blockage of NF-κB activation.
May 18, 2015
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2015 May 19. Epub 2015 May 19. PMID:
25993687
Article Published Date
: May 18, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Crohn's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D rescues impaired Mycobacterium tuberculosis-mediated tumor necrosis factor release in macrophages of HIV-seropositive individuals.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Infect Immun. 2013 Jan ;81(1):2-10. Epub 2012 Oct 15. PMID:
23071135
Article Published Date
: Dec 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin D
Diseases
:
HIV Infections
,
Mycobacterium Tuberculosis
,
Vitamin D Deficiency
Pharmacological Actions
:
Immunomodulatory
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D supplement may be a potential strategy for the oral lichen planus management.
Feb 22, 2017
Click here to read the entire abstract
Pubmed Data
: Oral Dis. 2017 Feb 23. Epub 2017 Feb 23. PMID:
28231625
Article Published Date
: Feb 22, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin D
Diseases
:
Oral Lichen Planus
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2020 Aug ;42(4):306-313. Epub 2020 May 18. PMID:
32419528
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cardioprotective effect of thymol against adrenaline-induced myocardial injury in rats.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2020 Jul ;6(7):e04431. Epub 2020 Jul 21. PMID:
32715125
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Thymol
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
[+]
Emodin exerts a protective effect in CVB3-mediated encephalitis in HFMD by inhibiting the TLR3 pathway.
Jul 05, 2020
Click here to read the entire abstract
Pubmed Data
: J Infect Dis. 2020 Jul 6 ;222(3):443-455. PMID:
32115640
Article Published Date
: Jul 05, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Coxsackievirus Infections
,
Encephalitis
,
Foot and Mouth Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiviral Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Jul 15 ;253:117671. Epub 2020 Apr 24. PMID:
32335165
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Piperine
Diseases
:
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The opposite effects of Antarctic krill oil and arachidonic acid-rich oil on bone resorption in ovariectomized mice.
Aug 18, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Aug 19 ;11(8):7048-7060. PMID:
32813003
Article Published Date
: Aug 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Osteoporosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Osteoprotective
[+]
The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Palliat Med. 2020 Jul ;9(4):2079-2089. Epub 2020 Jul 14. PMID:
32692224
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Vitexins
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitexin ameliorates chronic stress plub high fat diet-induced nonalcoholic fatty liver disease by inhibiting inflammation.
Sep 04, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Sep 5 ;882:173264. Epub 2020 Jun 13. PMID:
32544504
Article Published Date
: Sep 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Vitexins
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
"Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats."
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Clinics (Sao Paulo). 2008 Dec ;63(6):807-13. PMID:
19061005
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Liver Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antineoplastic Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
"Tanshinone IIA prevents uric acid nephropathy in rats through NF-κB inhibition."
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2012 Jun ;78(9):866-73. Epub 2012 May 15. PMID:
22588836
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Hyperuricemia
,
Uric Acid Nephropathy
Pharmacological Actions
:
NF-kappaB Inhibitor
Additional Keywords
:
Drug: Allopurinol
,
Natural Substances Versus Drugs
Problem Substances
:
Allopurinol
[+]
1,25(OH)2 D3 inhibited Th17 cells differentiation via regulating the NF-κB activity and expression of IL-17.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Prolif. 2018 Oct ;51(5):e12461. Epub 2018 Apr 24. PMID:
29687949
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Tuberculosis
Pharmacological Actions
:
Immunomodulatory
,
Immunomodulatory: Th17 downregulation
,
NF-kappaB Inhibitor
[+]
16α-hydroxytrametenolic acid from Poria cocos improves intestinal barrier function.
Oct 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Oct 2 ;67(39):10871-10879. Epub 2019 Sep 23. PMID:
31517482
Article Published Date
: Oct 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Poria cocos
Diseases
:
Gastrointestinal Diseases
,
Gastrointestinal Inflammation
,
Irritable Bowel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside may be a promising natural lead compound for treating early phases of colorectal cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:3634915. Epub 2017 Nov 7. PMID:
29238715
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
2-Methoxyestradiol attenuates testosterone-induced benign prostate hyperplasia.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:4389484. Epub 2018 Aug 1. PMID:
30154949
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
2-Methoxyestradiol
Diseases
:
Prostatic Hyperplasia: Benign
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID:
27468227
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Gene Expression Regulation
[+]
6-gingerol alleviates inflammatory injury in DSS-induced ulcerative colitis.
Jul 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Palliat Med. 2020 Jul 14. Epub 2020 Jul 14. PMID:
32692218
Article Published Date
: Jul 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
NF-kappaB Inhibitor
[+]
6-Gingerol attenuates renal damage in streptozotocin-induced diabetes.
Feb 27, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceutics. 2021 Feb 28 ;13(3). Epub 2021 Feb 28. PMID:
33670981
Article Published Date
: Feb 27, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Mar ;92:107367. Epub 2021 Jan 15. PMID:
33461160
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Lung Injury: Acute
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
Additional Keywords
:
Ventilator Mortality
[+]
6-Gingerol exerts protective effects against ischemia reperfusion induced intestinal mucosa injury.
Feb 03, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Feb 4 ;119:137-148. Epub 2017 Feb 4. PMID:
28167239
Article Published Date
: Feb 03, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ischemia
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-gingerol prevented DSS-induced chronic ulcerative colitis via anti-inflammatory and antioxidative mechanisms.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2018 Jan 1:960327117751235. Epub 2018 Jan 1. PMID:
29350052
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jan ;97:633-641. Epub 2017 Nov 6. PMID:
29101807
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypolipidemic
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-shogaol may be of value in protection against diabetic complications in kidney and heart.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2018 Sep ;31(5(Supplementary)):2109-2117. PMID:
30393220
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Cardiomyopathy
,
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
NF-kappaB Inhibitor
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A ashwagandha water extract suppressed the tumor growth of glioma cells.
Jul 25, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2015 Jul 26. Epub 2015 Jul 26. PMID:
26208698
Article Published Date
: Jul 25, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Glioma
Pharmacological Actions
:
Antiproliferative
,
Heat Shock Protein Down-Regulation
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A curcumin complex reduces acute lung injury severity.
Feb 03, 2012
Click here to read the entire abstract
Pubmed Data
: Am J Respir Cell Mol Biol. 2012 Feb 3. Epub 2012 Feb 3. PMID:
22312018
Article Published Date
: Feb 03, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lung Injury: Acute
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
A dietary supplement of nuciferine rich in lotus leaf may have potential for the prevention and treatment of hyperuricemia with kidney inflammation.
Jan 14, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jan 15 ;747:59-70. Epub 2014 Dec 8. PMID:
25499818
Article Published Date
: Jan 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lotus
Diseases
:
Hyperuricemia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
A methanolic extract of Tulsi leaves could decrease inflammation in the cardiac tissue of isoproterenol induced myocardial infarction in rats.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2015 Oct ;53(10):632-40. PMID:
26665293
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Inflammation
,
Myocardial Infarction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A mixture of flaxseed linusorbs, exerts anti-inflammatory effects.
Jun 03, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2020 Jun 4 ;10(6). Epub 2020 Jun 4. PMID:
32512905
Article Published Date
: Jun 03, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2021 ;65. Epub 2021 Jul 1. PMID:
34262422
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Autophagy Up-regulation
,
Gastrointestinal Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A standardized extract of neem has neuroprotective effects in partial sciatic nerve injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EXCLI J. 2017 ;16:546-565. Epub 2017 Apr 18. PMID:
28694757
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Neem
Diseases
:
Nerve Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A water extract of Lonicera japonica has a gastroprotective effect via antioxidant and anti-inflammatory activities.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 Feb ;22(2):140-151. Epub 2019 Jan 24. PMID:
30676853
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Alcohol Toxicity
,
Gastric Ulcer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-Ulcer Agents
,
Antioxidants
,
Gastroprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
A water-extracted polysaccharide from Lentinus edodes exerts direct antitumor effects by inducing apoptosis in colon cancer cells.
Nov 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Nov 21. Epub 2016 Nov 21. PMID:
27888812
Article Published Date
: Nov 20, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Shiitake Mushroom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bax/Bcl2 ratio: Increase
,
Caspase-3 Activation
,
NF-kappaB Inhibitor
Additional Keywords
:
Polysaccharides
[+]
A water-soluble extract from Actinidia arguta ameliorates psoriasis-like skin inflammation.
Oct 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Oct 2 ;10(10). Epub 2018 Oct 2. PMID:
30279326
Article Published Date
: Oct 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Kiwifruit
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-κB signaling pathway.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Behav Immun. 2019 07 ;79:228-235. Epub 2019 Feb 7. PMID:
30738841
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chrysin
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Ability of post-treatment glycyrrhizic acid to mitigate cerebral ischemia/reperfusion injury.
Sep 27, 2020
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2020 Sep 28 ;26:e926551. Epub 2020 Sep 28. PMID:
32981927
Article Published Date
: Sep 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Glycyrrhiza glabra
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Açaí juice attenuates atherosclerosis in ApoE deficient mice through antioxidant and anti-inflammatory activities.
Jun 01, 2011
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2011 Jun;216(2):327-33. Epub 2011 Feb 24. PMID:
21411096
Article Published Date
: Jun 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Acai
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Acetyl-11-keto-β-boswellic acid showed good antiosteoporotic activity.
Oct 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Oct 18 ;12(10). Epub 2020 Oct 18. PMID:
33081068
Article Published Date
: Oct 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
Diseases
:
Osteoporosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Osteoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2015 Jun 1 ;285(2):128-35. Epub 2015 Apr 19. PMID:
25902336
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.
Jul 22, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID:
31334539
Article Published Date
: Jul 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Mango leaf
Diseases
:
Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
NF-kappaB Inhibitor
Anti Therapeutic Actions
:
Western Diet
[+]
Administration of chlorogenic acid alleviates spinal cord injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2018 Jan ;17(1):1340-1346. Epub 2017 Nov 6. PMID:
29115619
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2016 Jan ;36(1):90-100. Epub 2015 Nov 10. PMID:
26773785
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Aduki bean
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aerobic training and green tea extract protect against N-Methyl-N-nitrosourea-induced prostate cancer.
May 28, 2019
Click here to read the entire abstract
Pubmed Data
: Med Sci Sports Exerc. 2019 May 29. Epub 2019 May 29. PMID:
31157709
Article Published Date
: May 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
Diseases
:
Prostate Cancer
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Chemopreventive
,
NF-kappaB Inhibitor
[+]
AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2014 Oct ;17(10):1057-63. Epub 2014 Sep 19. PMID:
25238199
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Aged garlic extract suppressed the proliferative activity in adenoma and adenocarcinoma lesions, but showed no effect on normal colon mucosa.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Mar ;33(3):1131-40. Epub 2014 Dec 30. PMID:
25573280
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Selective Antiproliferation
[+]
Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Mar 1 ;267:113500. Epub 2020 Oct 19. PMID:
33091499
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
[+]
Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway.
Mar 01, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Mar 2:173052. Epub 2020 Mar 2. PMID:
32135124
Article Published Date
: Mar 01, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Allicin provides protection against arsenic trioxide induced liver injury.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2017 Mar ;176(1):192-200. Epub 2016 Aug 25. PMID:
27561292
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Arsenic Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Nrf2 activation
Additional Keywords
:
Allicin
,
Antioxidants
,
Arsenic Poisoning
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
oxidative stress
Problem Substances
:
Arsenic Trioxide
[+]
Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2019 Feb ;46(1):241-250. Epub 2018 Nov 8. PMID:
30406889
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Brain: Oxidative Stress
,
Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Allyl isothiocyanate possesses antidiabetic, antioxidant, and anti-inflammatory activities in high-fat diet/streptozotocin-induced type 2 diabetes mellitus.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Jul ;33(7):e22328. Epub 2019 Mar 30. PMID:
30927557
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Allylmethylsulfide (AMS), a volatile organosulfur derivative from garlic has radioprotective properties.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Jun;12(3):542-51. PMID:
19627202
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Lipid Peroxidation
,
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Radioprotective
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Aloe vera gel could suppress colitis-related colon carcinogenesis.
Sep 29, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep 30 ;40:428-435. Epub 2016 Aug 30. PMID:
27697726
Article Published Date
: Sep 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Cell cycle arrest
,
Chemopreventive
,
NF-kappaB Inhibitor
[+]
Aloin could be used for ameliorating the progression of osteoarthritis.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2020 Dec ;89(Pt B):107079. Epub 2020 Oct 20. PMID:
33096361
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Alpha lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nephrol Dial Transplant. 2009 Oct;24(10):3012-20. Epub 2009 May 27. PMID:
19474282
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Alpha-lipoic acid could provide a potential treatment for atherosclerosis in postmenopausal patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;47(6):2261-2277. Epub 2018 Jul 5. PMID:
29975924
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
Additional Keywords
:
Ovariectomy-Induced Changes
[+]
Alpha-lipoic acid downregulates TRPV1 receptor via NF-κB and attenuates neuropathic pain in rats with diabetes.
Mar 15, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Neurosci Ther. 2020 Mar 16. Epub 2020 Mar 16. PMID:
32175676
Article Published Date
: Mar 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Alpha-lipoic acid improved neurological outcome in experimental stroke.
Jul 10, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 Jul 11 ;48(1):42-53. Epub 2018 Jul 11. PMID:
29996116
Article Published Date
: Jul 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-Lipoic acid is a new therapeutic method that can be used in the prevention-treatment of radiation-induced fibrosis.
Jan 19, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jan 20. Epub 2016 Jan 20. PMID:
26799284
Article Published Date
: Jan 19, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Radioprotective
[+]
Alpha-lipoic acid may protect patients with diabetes against COVID-19 infection.
Sep 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Hypotheses. 2020 Oct ;143:110185. Epub 2020 Aug 14. PMID:
33017914
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Coronavirus Infection
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
[+]
Alpha-mangostin could be used to delay the progression of osteoarthritis.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Nov ;52:156-162. Epub 2017 Oct 12. PMID:
28915439
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Garcinia Mangostana
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Alpha-tocopherol and ascorbic acid supplementation reduced acute lung inflammatory response by cigarette smoke.
Oct 31, 2006
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2006 Nov-Dec;22(11-12):1192-201. PMID:
17095405
Article Published Date
: Oct 31, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
,
Vitamin E: alpha tocopherol
Diseases
:
Lung Inflammation
,
Smoking
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne.
May 09, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 May 10 ;235:460-471. Epub 2019 Feb 13. PMID:
30771518
Article Published Date
: May 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Currant
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Ameliorative effect of aspalathin and nothofagin from rooibos on HMGB1-induced septic responses.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2015 ;43(5):991-1012. Epub 2015 Jul 30. PMID:
26224030
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Rooibos
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(10):e78061. Epub 2013 Oct 28. PMID:
24205091
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of natural herbals restores antitumor immunosurveillance and can be applied for prevention or treatment of inflammation-related cancers.
Mar 21, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Mar 22 ;102:420-427. Epub 2018 Mar 22. PMID:
29574282
Article Published Date
: Mar 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dandelion
,
Fig
,
Ginseng
Diseases
:
Cancers: All
,
Liver Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
NF-kappaB Inhibitor
[+]
Andrographis paniculate could be used to improve PM2.5-induced lung injury by modulating the NF-κB pathway.
Jul 12, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Jul 13 ;280:114420. Epub 2021 Jul 13. PMID:
34271116
Article Published Date
: Jul 12, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Air Pollution Linked Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Andrographolide ameliorates d-galactosamine/lipopolysaccharide-induced acute liver injury by activating Nrf2 signaling pathway.
Jun 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Jun 20 ;8(25):41202-41210. PMID:
28465482
Article Published Date
: Jun 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Andrographolide ameliorates diabetic cardiomyopathy.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:9086747. Epub 2018 Jun 25. PMID:
30046380
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Antioxidants
,
Apoptotic
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Andrographolide ameliorates diabetic retinopathy by inhibiting retinal angiogenesis and inflammation.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 2015 Apr ;1850(4):824-31. Epub 2015 Jan 29. PMID:
25641276
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Andrographolide inhibits influenza A virus-induced inflammation in a murine model through NF-κB and JAK-STAT signaling pathway.
Jan 11, 2017
Click here to read the entire abstract
Pubmed Data
: Microbes Infect. 2017 12 ;19(12):605-615. Epub 2017 Sep 7. PMID:
28889969
Article Published Date
: Jan 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Influenza A
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Andrographolide inhibits ovariectomy-induced bone loss.
Nov 16, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2015 Nov 17 ;16(11):27470-81. Epub 2015 Nov 17. PMID:
26593901
Article Published Date
: Nov 16, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Osteoporosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Osteoprotective
Additional Keywords
:
Ovariectomy-Induced Changes
[+]
Andrographolide may have therapeutic value in the treatment of stroke.
Sep 30, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2010 Oct ;161(3):668-79. PMID:
20880404
Article Published Date
: Sep 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
,
Andrographolide
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo.
Jan 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2014 Feb ;171(3):663-75. PMID:
24125472
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Andrographis
Diseases
:
Osteoporosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Osteoprotective
[+]
Anthocyanin-rich aronia berry extract mitigates high-fat and high-sucrose diet-induced adipose tissue inflammation.
Mar 21, 2021
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2021 Mar 22. Epub 2021 Mar 22. PMID:
33751905
Article Published Date
: Mar 21, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
High Fat Diet
,
High Sugar Diet
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2014 ;4:6234. Epub 2014 Aug 29. PMID:
25167935
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Raspberry
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins derived from Vitis coignetiae Pulliat contributes anti-cancer effects in Hep3B human hepatocellular carcinoma cells.
Nov 19, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Nov 20 ;25(22). Epub 2020 Nov 20. PMID:
33233701
Article Published Date
: Nov 19, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins from purple sweet potato and purple potato are good source of anti inflammatory phytochemicals to prevent alcoholic liver disease.
Mar 15, 2015
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2015 Mar 16:1-5. Epub 2015 Mar 16. PMID:
25774691
Article Published Date
: Mar 15, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Potato: Pigmented
,
Sweet Potato: Purple
Diseases
:
Alcoholic Liver Disease
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
MicroRNA modulator
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Risk Reduction
,
Significant Treatment Outcome
[+]
Anthocyanins in black rice, soybean and purple corn increase fecal butyric acid and prevent liver inflammation in high fat diet-induced obese mice.
Sep 19, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Sep 20 ;8(9):3178-3186. PMID:
28792056
Article Published Date
: Sep 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Corn: Purple
,
Rice
,
Soybean: Black
Diseases
:
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2016 Jan ;37(1):217-24. Epub 2015 Nov 3. PMID:
26531835
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Patchouli
Diseases
:
Allergies
,
Inflammation
Pharmacological Actions
:
Anti-Allergic Agents
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-hypoglycemic and hepatocyte-protective effects of hyperoside against high-carbohydrate/high-fat diet and alloxan-induced diabetes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Jan ;41(1):77-86. Epub 2017 Oct 25. PMID:
29115390
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
,
High Fat Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-Inflammatory action of blueberry polyphenols in HIG-82 rabbit synoviocytes.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 Oct ;22(10):1032-1040. Epub 2019 May 22. PMID:
31120380
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Polyphenols
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:6874692. Epub 2018 Oct 11. PMID:
30405742
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory and anti-gouty-arthritic effect of free Ginsenoside Rb1 and nano ginsenoside Rb1 against MSU induced gouty arthritis.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2020 Dec 1 ;332:109285. Epub 2020 Oct 7. PMID:
33038330
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Anti-inflammatory effect of allicin associated with fibrosis in pulmonary arterial hypertension.
Aug 09, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Aug 10 ;22(16). Epub 2021 Aug 10. PMID:
34445305
Article Published Date
: Aug 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effect of Centella asiatica phytosome in a mouse model of phthalic anhydride-induced atopic dermatitis.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Apr 1 ;43:110-119. Epub 2018 Apr 6. PMID:
29747743
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Apr 26, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Apr 27 ;17(1):233. Epub 2017 Apr 27. PMID:
28449676
Article Published Date
: Apr 26, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Ligustrazine
,
Resveratrol
Diseases
:
Arthritis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anti-inflammatory effect of Musa acuminata stem.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Dent. 2020 Mar ;14(2):294-298. Epub 2020 May 12. PMID:
32396971
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Banana Stem
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effects of eriocitrin against the dextran sulfate sodium-induced experimental colitis in murine model.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Nov ;33(11):e22400. Epub 2019 Oct 8. PMID:
31593355
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Inflammation
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.
Sep 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Sep 5 ;762:333-43. Epub 2015 Jun 6. PMID:
26054809
Article Published Date
: Sep 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2016 Apr 15 ;106:82-93. Epub 2016 Mar 3. PMID:
26947453
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Bone Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Anti-psoriatic effect of Lavandula angustifolia essential oil and its major components linalool and linalyl acetate.
Jul 01, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Jul 2:113127. Epub 2020 Jul 2. PMID:
32623016
Article Published Date
: Jul 01, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Lavender: Essential Oil
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
NF-kappaB Inhibitor
[+]
Antihyperuricemic effect of liquiritigenin in potassium oxonate-induced hyperuricemic rats.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Dec ;84:1930-1936. Epub 2016 Nov 15. PMID:
27863839
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Liquiritigenin
Diseases
:
Hyperuricemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Antioxidant-rich extract from plantaginis semen Ameliorates diabetic retinal injury in a streptozotocin-induced diabetic rat model.
Sep 17, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Sep 18 ;8(9). Epub 2016 Sep 18. PMID:
27649243
Article Published Date
: Sep 17, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Plantago asiatica
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Antioxidants
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID:
28282576
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Anxiolytic effects of Formononetin in an inflammatory pain model.
Jan 07, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Brain. 2019 04 8 ;12(1):36. Epub 2019 Apr 8. PMID:
30961625
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Anxiety Disorders
,
Inflammation
Pharmacological Actions
:
Anti-Anxiety Agents
,
NF-kappaB Inhibitor
[+]
Apigenin and naringenin can ameliorate glucose and lipid metabolism, as well as endothelial dysfunction in T2D rats
Jan 19, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Jan 20. Epub 2016 Jan 20. PMID:
26801071
Article Published Date
: Jan 19, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Naringenin
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Apigenin enhances the anti-tumor effect of gemcitabine.
Jan 18, 2008
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2008 Jan 18;259(1):39-49. Epub 2007 Oct 29. PMID:
17967505
Article Published Date
: Jan 18, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
Additional Keywords
:
Drug: Gemcitabine
,
Drug-Plant-Vitamin Synergies
[+]
Apigenin may be an alternative therapeutic option for prevention of sepsis-induced organ damage.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2016 Jun ;38(3):228-237. PMID:
27144896
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin reduces paraquat induced acute lung injury by inhibition of inflammation and oxidative stress.
Jan 18, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Jan 19. Epub 2016 Jan 19. PMID:
26782361
Article Published Date
: Jan 18, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Herbicide Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apigenin, a dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation in mice.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Arthritis Res Ther. 2009;11(2):R59. Epub 2009 Apr 30. PMID:
19405952
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Autoimmune Diseases
,
Lupus Erythematosus: Systemic
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Apocynin is as effective as α-methyl prednisolone in an animal model of Duchenne's Muscular Dystrophy.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2016 Apr ;106:101-13. Epub 2016 Feb 27. PMID:
26930420
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Duchenne's Muscular Dystrophy
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
Additional Keywords
:
Apocynin
,
Corticosteroid
,
Duchenne's Muscular Dystrophy
,
Natural Versus Synthetics
,
oxidative stress
Problem Substances
:
Corticosteroid
[+]
Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2019 ;16:49. Epub 2019 Jul 26. PMID:
31372176
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pineapple
,
Vinegar
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Apple polyphenols extract alleviated dextran sulfate sodium-induced ulcerative colitis.
Nov 19, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Nov 20. Epub 2020 Nov 20. PMID:
33215776
Article Published Date
: Nov 19, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Dysbiosis
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
NF-kappaB Inhibitor
[+]
Apple polysaccharide extracts could be used in combination therapy for the prevention of colitis-associated colon cancer.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(1):177-90. Epub 2014 Nov 20. PMID:
25412264
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apples
Diseases
:
Colitis
,
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Apple total triterpenoid content induced apoptosis in MDA-MB-231 cells.
Sep 18, 2012
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2012 Sep 19 ;60(37):9430-6. Epub 2012 Sep 6. PMID:
22924395
Article Published Date
: Sep 18, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apples
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Colon Cancer
,
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apricot supplementation and irradiation given in combination, offer maximum protection against DMBA-induced hepatic carcinogenesis.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Aug ;70:128-33. Epub 2014 May 10. PMID:
24819963
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy and Radiation Toxicity
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Arctigenin is a promising candidate for the treatment of osteoclast-related osteolytic diseases caused by excessive osteoclast formation.
Oct 13, 2018
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2018 Oct 14. Epub 2018 Oct 14. PMID:
30317692
Article Published Date
: Oct 13, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Bone Diseases
,
Titanium Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation.
Sep 09, 2020
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2020 Sep 10. Epub 2020 Sep 10. PMID:
32964428
Article Published Date
: Sep 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration.
Dec 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Exp Ther. 2001 Dec;299(3):832-9. PMID:
11714866
Article Published Date
: Dec 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Alcoholic Liver Disease
,
Inflammation
,
Liver Fibrosis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aronia berry might be a promising natural treatment for ulcerative colitis.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Jul ;20(7):667-675. Epub 2017 Jul 5. PMID:
28677983
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2020 Feb ;95(2):121-128. Epub 2019 Sep 6. PMID:
32064961
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Artemisinin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Artesunate exerts protective effects against ulcerative colitis .
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug ;20(2):1321-1332. Epub 2019 Jun 5. PMID:
31173225
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Artesunate suppresses inflammation and oxidative stress in a rat model of colorectal cancer.
Aug 29, 2019
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2019 Aug 30. Epub 2019 Aug 30. PMID:
31471932
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
