Nitric Oxide Inhibitor

Name	AC	CK
Curcumin	16	33
Resveratrol	11	19
Thymoquinone	7	16
Ginger	3	14
Arginine	7	12
Turmeric	3	12
L-Carnitine	1	10
Selenium	1	10
Strawberry	1	10
Stilbenes	5	9
Ginsenosides	5	7
Nigella sativa (aka Black Seed)	4	7
Rose	3	6
Dandelion	4	5
Flavonoids	3	5
Hesperidin	3	5
Melatonin	1	5
Tangeretin	3	5
Achiote	2	4
Astaxanthin	2	4
Barley	2	4
Bay leaf	3	4
Cannabinoids	2	4
Fermented Foods and Beverages	2	4
Garlic	2	4
Moringa oleifera	3	4
Noni	2	4
Patchouli	2	4
Propolis: Bee	2	4
Rosmarinic acid	2	4
Soy	2	4
Spirulina	2	4
Anthocyanins	2	3
Nettle	2	3
Nobiletin	2	3
Polyphenols	2	3
Rosemary	2	3
Sesamol	2	3
Vitamin C	2	3
Acai	1	2
Adlay	2	2
Agaricus brasiliensis	1	2
Aloe Vera	1	2
Avocado	1	2
Baicalein	1	2
Berberine	1	2
Berries: All	1	2
Beta-Caryophyllene	1	2
Black Tea	1	2
Camel Milk	1	2
Cannabidiol	1	2
Cannabigerol	1	2
Cannabis	1	2
Carrot	2	2
Chaga Mushroom (Inonotus obliquus)	1	2
Chinese Skullcap	1	2
Citrus Peel	1	2
Citrus naringin	1	2
Coenzyme Q10	1	2
Combretum fragrans	1	2
Damnacanthal	1	2
Delta-tetrahydrocannabinol (THC)	1	2
Diallyl sulfide	1	2
Genipin	1	2
Gingerol	1	2
Ginseng (American)	1	2
Grape Seed Extract	1	2
Gynostemma	1	2
Honey	1	2
Isothiocyanates	1	2
Japanese cypress	1	2
Loquat Leaves	2	2
Lotus	1	2
Lychee	1	2
Medicinal Mushrooms	1	2
Mulberry	1	2
Niacin	1	2
Omega-3 Fatty Acids	1	2
Palmitoylethanolamide	1	2
Panax Ginseng	1	2
Perilla	1	2
Phloretin	1	2
Piceatannol	1	2
Pine Needle	1	2
Puerarin	1	2
Quercetin	1	2
Red Wine	1	2
Reishi Mushroom	1	2
Rooibos	1	2
Rutin	1	2
Saffron	1	2
Safranal	1	2
Shiitake Mushroom	1	2
Soy: Fermented	1	2
Turmeric: Fermented	1	2
Unsaponifiables	1	2
Verbascoside	1	2
Virgin Coconut Oil	1	2
Vitamin E	1	2
Vitexins	1	2
Zataria multiflora	1	2
Achillea fragrantissima	1	1
Bacopa	1	1
Bai Zhu	1	1
Banana Peel	1	1
Barberry	1	1
Catechin	1	1
Cherry: All Varieties	1	1
Chlorella (Algae)	1	1
Chokeberry	1	1
Cocoa	1	1
Crescentia Alata	1	1
Cucurbitacin B	1	1
Cucurbitacin E	1	1
Curcumin: Lipidated	1	1
Ellagic Acid	1	1
Emodin	1	1
Fisetin	1	1
Fucoidan	1	1
Gallic Acid	1	1
Garlic: Aged	1	1
Ginseng (Korean)	1	1
Horseradish	1	1
Justicia gendarussa	1	1
Kimchi	1	1
Kiwifruit	1	1
Luteolin	1	1
Mangosteen	1	1
Maple Syrup	1	1
Maqui	1	1
Mushrooms: All	1	1
Naringenin	1	1
Nicotinamide	1	1
Orange	1	1
Paeoniflorin	1	1
Piperidines	1	1
Piperine	1	1
Pomegranate	1	1
Probiotics	1	1
Pterostilbene	1	1
Punicalagin	1	1
Pycnogenol (Pine Bark)	1	1
Salvia miltiorrhiza	1	1
Sembung Leaf	1	1
Sweet Potato: Purple	1	1
Tannic Acid	1	1
Tart Cherry	1	1
Tea	1	1
Tomato	1	1
Xanthohumol	1	1
Xanthones	1	1

[+]

Acupuncture treatment was effective at lowering NO levels which was found to be 55% higher in the migraine group compared to the controls. Dec 31, 2013

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Pubmed Data : Acupunct Electrother Res. 2014 ;39(3-4):275-83. PMID: 25693309

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Diseases : Headache: Migraine, Migraine Disorders

Therapeutic Actions : Acupuncture

Pharmacological Actions : Nitric Oxide Inhibitor

[+]

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.Aug 15, 2011

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Pubmed Data : J Oncol Pharm Pract. 2011 Aug 15. Epub 2011 Aug 15. PMID: 21844132

Article Published Date : Aug 15, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Nitric Oxide Inhibitor

Additional Keywords : Drug: Imatinib, Drug Synergy

[+]

Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.Dec 31, 2011

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Pubmed Data : Immunopharmacol Immunotoxicol. 2019 Aug ;41(4):497-503. Epub 2019 Jul 11. PMID: 31293216

Article Published Date : Jul 31, 2019

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Astragaloside

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Inflammatory cytokines upregulate transferrin synthesis, which may increase aluminum absorption by the brain after vaccination.Sep 01, 2000

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Pubmed Data : Anticancer Res. 2000 Sep-Oct;20(5A):3331-8. PMID: 11062761

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Pubmed Data : Int J Med Mushrooms. 2015 ;17(4):339-50. PMID: 25954960

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Agaricus brasiliensis, Medicinal Mushrooms, Reishi Mushroom

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nitric Oxide Inhibitor

[+]

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

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Pubmed Data : J Med Food. 2014 Oct ;17(10):1057-63. Epub 2014 Sep 19. PMID: 25238199

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2013 ;2013:463145. Epub 2013 Oct 3. PMID: 24224164

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Achiote

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

[+]

Anti-inflammatory and anti-aging evaluation of pigment-protein complex extracted from Chlorella Pyrenoidosa.Oct 15, 2019

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Pubmed Data : Arthritis Res Ther. 2009;11(2):R41. Epub 2009 Mar 16. PMID: 19291317

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med Princ Pract. 2011 ;20(2):142-6. Epub 2011 Jan 20. PMID: 21252569

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Substances : Achiote

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor

Additional Keywords : Plant Extracts

[+]

Boysenberry seed polyphenols have antihypertensive effects.Dec 31, 2011

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Pubmed Data : Biosci Biotechnol Biochem. 2012 ;76(9):1694-701. Epub 2012 Sep 7. PMID: 22972352

Article Published Date : Dec 31, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Berries: All

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents, Nitric Oxide Inhibitor, Vasodilator Agents

Additional Keywords : Plant Extracts, Proanthocyanidins

[+]

Camel milk attenuates rheumatoid arthritis in animals. Sep 19, 2017

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Pubmed Data : J Neurochem. 2009 Aug;110(4):1276-87. Epub 2009 Jun 10. PMID: 19519665

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Pubmed Data : Biosci Biotechnol Biochem. 2011 ;75(10):1971-6. Epub 2011 Oct 7. PMID: 21979071

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Substances : Barley, Fermented Foods and Beverages

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Nitric Oxide Inhibitor

Additional Keywords : Plant Extracts

[+]

Fermented C. longa might be a useful material for preventing impairment of learning and memory.Jul 16, 2017

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Pubmed Data : Surgery. 2005 Aug;138(2):291-8. PMID: 16153439

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Noni, and its major bioactive component damnacanthal, exhibits anti-inflammatory properties. Nov 01, 2011

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Pubmed Data : Inflamm Allergy Drug Targets. 2011 Nov 1. Epub 2011 Nov 1. PMID: 21999179

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Substances : Damnacanthal, Noni

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor

[+]

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.Jun 30, 2014

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Pubmed Data : Nutr Res. 2014 Jul ;34(7):595-603. Epub 2014 Jun 14. PMID: 25150118

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Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Jul;29(7):639-41. PMID: 19852300

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Patchouli

Diseases : Bowel Surgery, Colon Surgery, Gastrointestinal Diseases, Short Bowel Syndrome

Pharmacological Actions : Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Perilla frutescens and its active compound rosmarinic acid have beneficial effects on cognitive improvement and may help prevent Alzheimer's disease.May 31, 2016

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Pubmed Data : J Ethnopharmacol. 2019 Oct 12 ;248:112303. Epub 2019 Oct 12. PMID: 31614204

Article Published Date : Oct 11, 2019

Study Type : Animal Study

Additional Links

Substances : Noni

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor

Additional Keywords : Polysaccharides

[+]

Portulaca oleracea extract had protective effects on acute alcoholic liver injury.Aug 07, 2019

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Pubmed Data : Korean J Ophthalmol. 2010 Apr;24(2):108-18. Epub 2010 Apr 6. PMID: 20379461

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Pubmed Data : Pharm Biol. 2013 Aug ;51(8):1066-76. Epub 2013 Jun 7. PMID: 23746221

Article Published Date : Jul 31, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Barley

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

The ameliorative effect of berberine and coenzyme Q10 in an ovalbumin-induced allergic rhinitis model.Sep 30, 2018

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Pubmed Data : Eur Arch Otorhinolaryngol. 2018 Oct ;275(10):2495-2505. Epub 2018 Aug 23. PMID: 30159729

Article Published Date : Sep 30, 2018

Study Type : Animal Study

Additional Links

Substances : Berberine, Coenzyme Q10

Diseases : Allergic Rhinitis

Pharmacological Actions : interleukin-13 down-regulation, Interleukin-4 downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor

[+]

The flower extract of Rosa rugosa may be a beneficial anti-inflammatory agent.Feb 29, 2016

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Pubmed Data : Biomol Ther (Seoul). 2016 Mar 1 ;24(2):184-90. PMID: 26797110

Article Published Date : Feb 29, 2016

Study Type : Animal Study

Additional Links

Substances : Rose

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

The results indicate a potential for therapeutic use of cannabidiol in chronic painful states.Feb 04, 2007

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Pubmed Data : Eur J Pharmacol. 2007 Feb 5 ;556(1-3):75-83. Epub 2006 Nov 10. PMID: 17157290

Article Published Date : Feb 04, 2007

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Hyperalgesia, Inflammation, Neuropathic Pain

Pharmacological Actions : NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.Feb 19, 2017

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Pubmed Data : Iran J Kidney Dis. 2017 Mar ;11(2):142-150. PMID: 28270647

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Pubmed Data : Biomed Pharmacother. 2018 Mar ;99:583-590. Epub 2018 Feb 20. PMID: 29710456

Article Published Date : Feb 28, 2018

Study Type : Animal Study

Additional Links

Substances : Vitexins

Diseases : Middle Cerebral Artery Occlusion (MCAO)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Autophagy Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Z. multiflora essential oil has the potential to be used in the therapy of oxidative damage.Sep 30, 2012

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Pubmed Data : J Pharm Pharmacol. 2012 Oct ;64(10):1491-500. Epub 2012 Apr 5. PMID: 22943180

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Pubmed Data : Int Immunopharmacol. 2019 Jul ;72:301-307. Epub 2019 Apr 18. PMID: 31005040

Article Published Date : Jun 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Oridonin

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : ScientificWorldJournal. 2013 ;2013:434151. Epub 2013 Dec 9. PMID: 24385881

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Pubmed Data : Planta Med. 2005 Aug;71(8):706-10. PMID: 16142632

Article Published Date : Aug 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Bay leaf

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Nitric Oxide Inhibitor

Additional Keywords : Plant Extracts

[+]

C. vulgaris possesses significant anti-inflammatory activity and could be a potential anti-inflammatory agent of natural origin.Mar 31, 2016

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Pubmed Data : Nat Prod Res. 2017 Jul 20:1-6. Epub 2017 Jul 20. PMID: 28726500

Article Published Date : Jul 19, 2017

Study Type : In Vitro Study

Additional Links

Substances : Turmeric

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor

[+]

Crescentia alata exhibits anti-inflammatory properties confirming its traditional use in Guatemala herbalism. Dec 21, 2001

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Pubmed Data : Life Sci. 2001 Dec 21;70(5):523-34. PMID: 11811897

Pubmed Data : J Med Food. 2014 Oct 10. Epub 2014 Oct 10. PMID: 25302660

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Pubmed Data : Pharm Biol. 2011 Jun ;49(6):648-52. PMID: 21554007

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Pubmed Data : Am J Chin Med. 2010;38(5):985-94. PMID: 20821828

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Loquat Leaves

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor

[+]

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells Mar 22, 2016

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Pubmed Data : Free Radic Biol Med. 2016 Mar 23. Epub 2016 Mar 23. PMID: 27016074

Article Published Date : Mar 22, 2016

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation

[+]

M. oleifera extracts suppressed the expression of inflammatory mediators in LPS stimulated macrophages.Sep 30, 2015

Pubmed Data : Int Immunopharmacol. 2019 Jul 17 ;75:105742. Epub 2019 Jul 17. PMID: 31325727

Article Published Date : Jul 16, 2019

Study Type : In Vitro Study

Additional Links

Substances : Myricetin

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Naringenin exerts anti-inflammatory effects in paraquat-treated SH-SY5Y cells.Feb 05, 2018

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Pubmed Data : Neurochem Res. 2018 Feb 6. Epub 2018 Feb 6. PMID: 29411263

Article Published Date : Feb 05, 2018

Study Type : In Vitro Study

Additional Links

Substances : Naringenin

Diseases : Pesticide Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Anti-Inflammatory Agents, Naringenin, Pesticide Toxicity

[+]

Neochlorogenic acid might act as a natural anti-inflammatory agent for the treatment of acute pneumonia.Mar 17, 2020

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Pubmed Data : J Ethnopharmacol. 2014 Feb 3 ;151(2):791-9. Epub 2013 Dec 1. PMID: 24296088

Article Published Date : Feb 02, 2014

Study Type : In Vitro Study

Additional Links

Substances : Bai Zhu

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor

Additional Keywords : Plant Extracts

[+]

Polysaccharides from M. conica play a potential role on immunomodulation and treating related diseases.Apr 30, 2012

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Pubmed Data : Appl Microbiol Biotechnol. 2012 May ;94(3):763-71. Epub 2011 Dec 11. PMID: 22159604

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Pubmed Data : J Agric Food Chem. 2008 Aug 27;56(16):7502-9. Epub 2008 Jul 26. PMID: 18656926

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Pubmed Data : Biomed Res Int. 2015 ;2015:768093. Epub 2015 Oct 5. PMID: 26509161

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Sweet Potato: Purple

Diseases : Breast Cancer, Colon Cancer, Gastric Cancer, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Dose Response, Plant Extracts

[+]

Pycnogenol has potential as a therapeutic agent for the treatment of allergic asthma.Nov 30, 2013

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Pubmed Data : Food Chem Toxicol. 2013 Dec ;62:681-6. Epub 2013 Oct 9. PMID: 24120901

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Pubmed Data : Clin Exp Pharmacol Physiol. 2010 May;37(5-6):630-5. Epub 2010 Feb 4. PMID: 20132235

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Chem. 2018 Aug 15 ;257:143-149. Epub 2018 Feb 24. PMID: 29622190

[+]

These findings showed that fisetin improves Meglumine antimoniate side effects as well as prevent the growth of promastigotes.May 31, 2017

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Pubmed Data : Pathog Glob Health. 2017 Jun ;111(4):176-185. Epub 2017 Apr 7. PMID: 28385129

Article Published Date : May 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Fisetin

Diseases : Leishmaniasis

Pharmacological Actions : Leishmanicidal, Nitric Oxide Inhibitor

[+]

These results demonstrate the immunomodulatory effects of L. barbarium polysaccharides and its effective uptake by macrophages and intestine.Mar 15, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Mar 16 ;25(6). Epub 2020 Mar 16. PMID: 32188121

Article Published Date : Mar 15, 2020

Study Type : In Vitro Study

Additional Links

Substances : Goji

Pharmacological Actions : Immunomodulatory, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Polysaccharides

[+]

These results imply that cucurbitacin E possesses powerful anti-encephalitogenic activity.Jun 21, 2016

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Pubmed Data : J Agric Food Chem. 2016 Jun 22 ;64(24):4900-7. Epub 2016 Jun 8. PMID: 27225664

Article Published Date : Jun 21, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cucurbitacin E

Diseases : Autoimmune Diseases, Encephalitis

Pharmacological Actions : Antioxidants, Interferon Gamma Reducer, Interleukin-17 downregulation, MicroRNA modulator, Nitric Oxide Inhibitor

[+]

These results provide further evidence of Bacopa monnieri for managing diseases involving chronic systemic and brain inflammation.Feb 28, 2014

Pubmed Data : Int J Biol Macromol. 2015 Sep ;80:246-52. Epub 2015 Jun 27. PMID: 26123819

Article Published Date : Aug 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Adlay

Pharmacological Actions : Immunomodulatory, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Polysaccharides

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Acupuncture treatment was effective at lowering NO levels which was found to be 55% higher in the migraine group compared to the controls. Dec 31, 2013

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.Aug 15, 2011

Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.Dec 31, 2011

Electro-acupuncture add-on treatment markedly improves activity of daily living and quality of life of Parkinson's disease patients.Dec 31, 2014

Ginger powder supplementation can reduce inflammatory markers in patients with knee osteoarthritis.Jun 30, 2016

L-carnitine applied at a 3 g dose provides strong antioxidant action by increasing the GSH and NOx level and decreasing the TBARs level.Dec 31, 2014

Phyllanthus amarus could alleviate knee pain and significantly reduce systemic anti-inflammatory effects in knee osteoarthritis patients.Aug 31, 2019

Selenium supplementation among diabetic nephropathy patients had favourable effects on serum MMP-2, plasma NO, TAC and GSH.Sep 19, 2016

Statin drugs alter platelet function. Dec 01, 2002

These results suggest that repeated sauna therapy may protect against oxidative stress, which leads to the prevention of atherosclerosis.Feb 29, 2004

Astragaloside potentially serve as a promising and effective therapeutic agent for treating osteoarthritis patients.Jul 31, 2019

Inflammatory cytokines upregulate transferrin synthesis, which may increase aluminum absorption by the brain after vaccination.Sep 01, 2000

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Thymoquinone represents a prospective treatment option to combat Mycobacterium tuberculosis infection.May 24, 2017

6-gingerol may be useful in the prevention and treatment of alzheimer's disease.Mar 25, 2015

A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.Dec 31, 2017

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Acteoside reduces HMGB1 release and may be beneficial for the treatment of sepsis.Mar 31, 2013

Administration of medicinal mushrooms under experimental diabetes showed a positive corrective action on the L-arginine/NO system and the ratio between p53 and Bcl-2 proteins.Dec 31, 2014

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

Aloe vera could be considered an effective therapeutic agent for the treatment of sepsis.May 10, 2017

American ginseng prevents and treats Ulcerative Colitis.Sep 18, 2008

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

Anti-inflammatory and anti-aging evaluation of pigment-protein complex extracted from Chlorella Pyrenoidosa.Oct 15, 2019

Antiarthritic effect of lonicerin on Candida albicans arthritis in mice.Apr 30, 2011

Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy.May 31, 2019

Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice.Jun 30, 2003

Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression.Oct 14, 2004

Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis.Feb 14, 2012

Astaxanthin improves cognitive deficits from oxidative stress in diabetes rats.Dec 31, 2014

Astaxanthin may be benefit for prevention and treatment of preeclampsia disease.Sep 30, 2014

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo.Sep 30, 2019

Avocado/soybean unsaponifiables have a protective effect against experimental dog osteoarthritis. Jan 01, 2009

Baicalein improves learning and memory dysfunction in D-gal induced aging rats.May 25, 2017

Bay leaf contains compounds which inhibit LPS-activated nitric oxide production and which induce heat shock protein. Apr 21, 2000

Beta-Caryophyllene ameliorates the development of experimental autoimmune encephalomyelitis.Apr 28, 2017

Betulinic acid protects against cerebral ischemia-reperfusion injury.Apr 29, 2011

Bixa orellana leaves extract inhibits bradykinin-induced inflammation.Dec 31, 2010

Boysenberry seed polyphenols have antihypertensive effects.Dec 31, 2011

Camel milk attenuates rheumatoid arthritis in animals. Sep 19, 2017

Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.Apr 30, 2013

Cannabinoids seem to protect neurons against NMDA toxicity.Feb 28, 2006

Carthamus tinctorius extract ameliorated hemodynamic alteration and vascular remodelling in 2K-1C hypertensive rats.Feb 28, 2018

Chinese skullcap (Scutellaria baicalensis) significantly improves functional recovery from spinal cord injury in rats by inhibiting inflammation and oxidative stress after injury.Aug 01, 2009

Cordyceps militaris could have the protective role from cognitive impairment and progression of Alzheimer's disease.May 31, 2019

Curcumin attenuates ovalbumin-induced airway inflammation.Oct 17, 2008

Curcumin inhibits nitric oxide production. Jun 15, 1998

Curcumin might be useful in the chemoprevention of colorectal cancer in individuals consuming an high-protein diet.Jul 31, 2015

Curcumin prevents colon carcinogenesis. Apr 01, 1999

Curcumin prevents shock-wave lithotripsy-induced renal injury.Jun 01, 2009

Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.Jan 01, 2009

Diallyl sulfide and diallyl disulfide exert therapeutic effects in the DNBS model of colitis.Feb 28, 2015

Dietary kaempferol suppresses inflammation of dextran sulfate sodium-induced colitis.Jan 31, 2012

Dietary omega-3 fatty acids positively modulate the substrate for post-operative atrial fibrillation in a canine cardiac surgery model.Mar 01, 2011

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice.Jan 01, 2010

Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

Essential oils extracted from Chamaecyparis obtusa may be considered an effective therapeutic agent for the treatment of inflammatory diseases.Mar 31, 2016

Evaluation of data supported the anti-inflammatory activities of thymoquinone, so it may be investigated as an effective anti-inflammatory drug in rheumatoid arthritis.Apr 30, 2015

Extracts of R. officinalis and rosmarinic acid through modulating neuro-inflammation might be potential candidates in treating neuropathic pain.Dec 21, 2016

Extremely low frequency electromagnetic fields alter nitric oxide activiy.Oct 26, 1998

Fermented barley extract effectively inhibited the propagation of inflammation by suppressing oxidative stress.Dec 31, 2010

Fermented C. longa might be a useful material for preventing impairment of learning and memory.Jul 16, 2017

Fermented soybean has anti-inflammatory properties in the kidney of high-fat-fed rats.Jul 01, 1987

Genipin inhibited LPS-induced inflammatory response by activating Nrf2 signalling pathway in BV2 microglia.Sep 30, 2017

Ginger inhibits micoglial cell activiation associated with brain inflammation. Jun 01, 2009

Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury.Sep 30, 2018

Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats.Feb 28, 2015

Grape seed proanthocyanidin extract alleviates urethral dysfunction in diabetic rats.Dec 31, 2017

Gypenosides attenuated cholesterol induced DNA damage by inhibiting ROS production.Mar 31, 2015

Hesperidin might improve the endothelium-dependent vasodilation during hypertension.Sep 30, 2016

Honey has anti-inflammatory properties likely due to its nitric oxide inhibitory properties. Apr 01, 2011

Intranasal curcumin alleviate paraquat induced pulmonary damage and pro-inflammatory cytokine levels like tumor necrosis factor-α (TNF-α) and nitric oxide (NO).Oct 31, 2014

Nitric Oxide Inhibitor

View the Evidence:
248 Abstracts with Nitric Oxide Inhibitor Research