Nitric Oxide Inhibitor

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187 Substances Researched for Nitric Oxide Inhibitor
NameACCKFocus
Curcumin1735Locked
Resveratrol1119Locked
Thymoquinone716Locked
Ginger314Locked
Arginine712Locked
Phyllanthus amarus 212Locked
Turmeric312Locked
L-Carnitine110Locked
Selenium110Locked
Strawberry110Locked
Stilbenes59Locked
Vitamin C59Locked
Flavonoids58Locked
Astragaloside27Locked
Fermented Foods and Beverages47Locked
Ginsenosides57Locked
Nigella sativa (aka Black Seed)47Locked
Rose 47Locked
Noni36Locked
Polyphenols46Locked
Dandelion 45Locked
Hesperidin35Locked
Melatonin15Locked
Patchouli35Locked
Tangeretin 35Locked
Achiote24Locked
Astaxanthin24Locked
Barley24Locked
Bay leaf34Locked
Cannabinoids 24Locked
Garlic24Locked
Moringa oleifera34Locked
Nobiletin 34Locked
Propolis: Bee24Locked
Quercetin24Locked
Rosmarinic acid24Locked
Soy24Locked
Spirulina24Locked
Sulforaphane24Locked
Anthocyanins23Locked
Baicalein23Locked
Chlorella (Algae)23Locked
Honey23Locked
Kaempferol23Locked
Medicinal Mushrooms23Locked
Mulberry23Locked
Nettle23Locked
Pine Needle23Locked
Rosemary23Locked
Saffron23Locked
Sesamol23Locked
Acai12Locked
Adlay22Locked
Agaricus brasiliensis12Locked
Aloe Vera12Locked
Avocado12Locked
Berberine12Locked
Berries: All12Locked
Beta-Caryophyllene12Locked
Betulinic acid12Locked
Black Tea12Locked
Camel Milk 12Locked
Cannabidiol12Locked
Cannabigerol 12Locked
Cannabis12Locked
Carrot22Locked
Carvacrol12Locked
Chaga Mushroom (Inonotus obliquus)12Locked
Chinese Skullcap 12Locked
Citrus Peel 12Locked
Citrus naringin12Locked
Coenzyme Q1012Locked
Combretum fragrans12Locked
Cordyceps Militaris12Locked
Cordyceps sinensis12Locked
Damnacanthal12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Diallyl sulfide12Locked
Diosmetin12Locked
Genipin12Locked
Gingerol 12Locked
Ginseng (American)12Locked
Grape Seed Extract12Locked
Gynostemma12Locked
Honeysuckle12Locked
Isothiocyanates12Locked
Japanese cypress12Locked
Loquat Leaves22Locked
Lotus 12Locked
Lychee12Locked
Magnolol12Locked
Niacin12Locked
Okra12Locked
Omega-3 Fatty Acids12Locked
Paeonol12Locked
Palmitoylethanolamide 12Locked
Panax Ginseng12Locked
Panax Notoginseng12Locked
Peony22Locked
Perilla 12Locked
Phellinus Linteus22Locked
Phloretin12Locked
Piceatannol 12Locked
Plantago asiatica12Locked
Pterostilbene22Locked
Puerarin12Locked
Punicalagin22Locked
Purslane12Locked
Red Wine12Locked
Reishi Mushroom12Locked
Rooibos12Locked
Rutin12Locked
Safflower12Locked
Safranal12Locked
Shiitake Mushroom 12Locked
Soy: Fermented12Locked
Sweet Potato: Purple22Locked
Theanine12Locked
Turmeric: Fermented12Locked
Unsaponifiables 12Locked
Urolithin A 12Locked
Verbascoside12Locked
Virgin Coconut Oil12Locked
Vitamin E12Locked
Vitexins12Locked
White Tea12Locked
Zataria multiflora12Locked
Achillea fragrantissima11Locked
Bacopa11Locked
Bai Zhu11Locked
Banana Peel11Locked
Barberry11Locked
Bee Propolis11Locked
Bitter Orange11Locked
Blackberry11Locked
Catechin 11Locked
Cherry: All Varieties11Locked
Chia11Locked
Chokeberry11Locked
Cocoa11Locked
Crescentia Alata 11Locked
Cucurbitacin B 11Locked
Cucurbitacin E 11Locked
Curcumin: Lipidated11Locked
Ellagic Acid11Locked
Emodin11Locked
Fisetin11Locked
Fucoidan11Locked
Gallic Acid11Locked
Garlic: Aged11Locked
Ginseng (Korean)11Locked
Goji11Locked
Horseradish11Locked
Jujube11Locked
Justicia gendarussa11Locked
Kimchi11Locked
Kiwifruit11Locked
Luteolin11Locked
Mangiferin11Locked
Mangosteen11Locked
Maple Syrup11Locked
Maqui 11Locked
Marjoram11Locked
Mushrooms: All 11Locked
Myricetin11Locked
Naringenin 11Locked
Nicotinamide11Locked
Oleanolic acid11Locked
Orange11Locked
Oridonin11Locked
Orthosiphon11Locked
Paeoniflorin11Locked
Piperidines11Locked
Piperine11Locked
Pomegranate11Locked
Probiotics11Locked
Pumpkin11Locked
Pycnogenol (Pine Bark)11Locked
Salvia miltiorrhiza11Locked
Sembung Leaf11Locked
Tannic Acid11Locked
Tart Cherry11Locked
Tea11Locked
Tomato11Locked
Wogonin11Locked
Xanthohumol11Locked
Xanthones11Locked

View the Evidence:
310 Abstracts with Nitric Oxide Inhibitor Research

[+]

Magnesium supplementation may significantly reduce different human inflammatory markers.Feb 04, 2022

Pubmed Data : Nutrients. 2022 Feb 5 ;14(3). Epub 2022 Feb 5. PMID: 35277037
Article Published Date : Feb 04, 2022
Study Type : Meta Analysis
Additional Links
Substances : Magnesium
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Acupuncture treatment was effective at lowering NO levels which was found to be 55% higher in the migraine group compared to the controls. Dec 31, 2013

Pubmed Data : Acupunct Electrother Res. 2014 ;39(3-4):275-83. PMID: 25693309
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Headache: Migraine, Migraine Disorders
Therapeutic Actions : Acupuncture
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.Aug 15, 2011

Pubmed Data : J Oncol Pharm Pract. 2011 Aug 15. Epub 2011 Aug 15. PMID: 21844132
Article Published Date : Aug 15, 2011
Study Type : Human Study
Additional Links
Substances : Curcumin, Turmeric
Diseases : Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Drug: Imatinib, Drug Synergy
[+]

Dietary strawberries significantly decreased the histologic grade of patients' precancerous esophageal lesions.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Prev Res (Phila). 2012 Jan ;5(1):41-50. Epub 2011 Dec 1. PMID: 22135048
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Strawberry
Diseases : Esophageal Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts, Risk Reduction
[+]

Electro-acupuncture add-on treatment markedly improves activity of daily living and quality of life of Parkinson's disease patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:692795. Epub 2015 Aug 13. PMID: 26351515
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Quality of Life: Poor
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Fermented Carica papaya and Morinda citrifolia as perspective food supplements for the treatment of post-COVID symptoms.May 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 May 25 ;14(11). Epub 2022 May 25. PMID: 35684003
Article Published Date : May 24, 2022
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Noni, Papaya
Diseases : Coronavirus Infection
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nitric Oxide Inhibitor
[+]

Ginger powder supplementation can reduce inflammatory markers in patients with knee osteoarthritis.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2016 Jul ;6(3):199-203. Epub 2015 Jan 28. PMID: 27419081
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Ginger
Diseases : C-Reactive Protein, Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

L-carnitine applied at a 3 g dose provides strong antioxidant action by increasing the GSH and NOx level and decreasing the TBARs level.Dec 31, 2014

Pubmed Data : J Sports Med Phys Fitness. 2015 Jan-Feb;55(1-2):9-15. Epub 2014 Oct 7. PMID: 25289711
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : L-Carnitine
Diseases : Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
[+]

Phyllanthus amarus could alleviate knee pain and significantly reduce systemic anti-inflammatory effects in knee osteoarthritis patients.Aug 31, 2019

Pubmed Data : Chin J Integr Med. 2019 Sep ;25(9):691-695. Epub 2019 Oct 24. PMID: 31650487
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Phyllanthus amarus
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Selenium supplementation among diabetic nephropathy patients had favourable effects on serum MMP-2, plasma NO, TAC and GSH.Sep 19, 2016

Pubmed Data : Br J Nutr. 2016 Sep 20:1-7. Epub 2016 Sep 20. PMID: 27647263
Article Published Date : Sep 19, 2016
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Matrix metalloproteinase-2 (MMP-2) inhibitor, Nitric Oxide Inhibitor
[+]

Statin drugs alter platelet function. Dec 01, 2002

Pubmed Data : Eur J Clin Invest. 2002 Dec ;32(12):901-8. PMID: 12534449
Article Published Date : Dec 01, 2002
Study Type : Human Study
Additional Links
Diseases : Blood Platelet Disorders
Pharmacological Actions : Nitric Oxide Inhibitor
Problem Substances : Atorvastatin, Fluvastatin, Pravastatin , Simvastatin, Statin Drugs
[+]

These results suggest that repeated sauna therapy may protect against oxidative stress, which leads to the prevention of atherosclerosis.Feb 29, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Jpn Heart J. 2004 Mar ;45(2):297-303. PMID: 15090706
Article Published Date : Feb 29, 2004
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease, Endothelial Dysfunction, High Cholesterol, Hypertension, Oxidative Stress
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Astragaloside potentially serve as a promising and effective therapeutic agent for treating osteoarthritis patients.Jul 31, 2019

Pubmed Data : Immunopharmacol Immunotoxicol. 2019 Aug ;41(4):497-503. Epub 2019 Jul 11. PMID: 31293216
Article Published Date : Jul 31, 2019
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Astragaloside
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Inflammatory cytokines upregulate transferrin synthesis, which may increase aluminum absorption by the brain after vaccination.Sep 01, 2000

Pubmed Data : Anticancer Res. 2000 Sep-Oct;20(5A):3331-8. PMID: 11062761
Article Published Date : Sep 01, 2000
Study Type : Human In Vitro
Additional Links
Diseases : Vaccine-induced Toxicity
Pharmacological Actions : Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Pubmed Data : J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID: 22348531
Article Published Date : Aug 31, 2012
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Thymoquinone represents a prospective treatment option to combat Mycobacterium tuberculosis infection.May 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 May 25 ;17(1):279. Epub 2017 May 25. PMID: 28545436
Article Published Date : May 24, 2017
Study Type : Human In Vitro
Additional Links
Substances : Thymoquinone
Diseases : Mycobacterium Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

6-gingerol may be useful in the prevention and treatment of alzheimer's disease.Mar 25, 2015

Pubmed Data : Rejuvenation Res. 2015 Mar 26. Epub 2015 Mar 26. PMID: 25811848
Article Published Date : Mar 25, 2015
Study Type : Animal Study
Additional Links
Substances : Ginger, Gingerol
Diseases : Alzheimer's Disease, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8987173. Epub 2018 Aug 5. PMID: 30174782
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Okra
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Nrf2 activation
[+]

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Pubmed Data : PLoS One. 2016 ;11(11):e0166059. Epub 2016 Aug 16. PMID: 27851787
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Acai
Diseases : Endometriosis
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Nitric Oxide Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Acteoside reduces HMGB1 release and may be beneficial for the treatment of sepsis.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cells. 2013 Apr ;35(4):348-54. Epub 2013 Apr 4. PMID: 23563799
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Verbascoside
Diseases : Sepsis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation
[+]

Administration of medicinal mushrooms under experimental diabetes showed a positive corrective action on the L-arginine/NO system and the ratio between p53 and Bcl-2 proteins.Dec 31, 2014

Pubmed Data : Int J Med Mushrooms. 2015 ;17(4):339-50. PMID: 25954960
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Agaricus brasiliensis, Medicinal Mushrooms, Reishi Mushroom
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nitric Oxide Inhibitor
[+]

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

Pubmed Data : J Med Food. 2014 Oct ;17(10):1057-63. Epub 2014 Sep 19. PMID: 25238199
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

Aloe vera could be considered an effective therapeutic agent for the treatment of sepsis.May 10, 2017

Pubmed Data : Am J Chin Med. 2017 May 11:1-15. Epub 2017 May 11. PMID: 28490235
Article Published Date : May 10, 2017
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

American ginseng prevents and treats Ulcerative Colitis.Sep 18, 2008

Pubmed Data : Carcinogenesis. 2008 Sep 18. [Epub ahead of print] PMID: 18802031
Article Published Date : Sep 18, 2008
Study Type : Animal Study
Additional Links
Substances : Ginseng (American)
Diseases : Colitis: Pseudomembranous, Ulcerative Colitis
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, Tumor Suppressor Protein p53 Upregulation
[+]

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2013 ;2013:463145. Epub 2013 Oct 3. PMID: 24224164
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Achiote
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Plant Extracts
[+]

Anti-Inflammatory activity and chemical analysis of different fractions from Solidago chilensis inflorescence.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:7612380. Epub 2021 Oct 29. PMID: 34745422
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Goldenrod
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor
[+]

Anti-inflammatory and anti-aging evaluation of pigment-protein complex extracted from Chlorella Pyrenoidosa.Oct 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Oct 16 ;17(10). Epub 2019 Oct 16. PMID: 31623220
Article Published Date : Oct 15, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Aging, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antiarthritic effect of lonicerin on Candida albicans arthritis in mice.Apr 30, 2011

Pubmed Data : Arch Pharm Res. 2011 May ;34(5):853-9. Epub 2011 Jun 9. PMID: 21656372
Article Published Date : Apr 30, 2011
Study Type : Animal Study
Additional Links
Substances : Honeysuckle
Diseases : Arthritis, Candida Albicans
Pharmacological Actions : Antifungal Agents, Immunomodulatory, Nitric Oxide Inhibitor
[+]

Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy.May 31, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Jun ;392(6):697-713. Epub 2019 Feb 13. PMID: 30759263
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Combretum fragrans
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Antinoceceptive , Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice.Jun 30, 2003

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2003 Jul ;285(1):R50-6. Epub 2003 Mar 13. PMID: 12637347
Article Published Date : Jun 30, 2003
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Oxidative Stress, Sepsis
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
[+]

Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression.Oct 14, 2004

Pubmed Data : Free Radic Biol Med. 2004 Oct 15 ;37(8):1282-9. PMID: 15451067
Article Published Date : Oct 14, 2004
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Sepsis
Pharmacological Actions : Nitric Oxide Inhibitor, Vasodilator Agents
[+]

Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis.Feb 14, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2012 Feb 15 ;302(4):R409-16. Epub 2011 Nov 23. PMID: 22116513
Article Published Date : Feb 14, 2012
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Sepsis
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
[+]

Astaxanthin improves cognitive deficits from oxidative stress in diabetes rats.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(6):6083-94. Epub 2015 Jun 1. PMID: 26261486
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Diabetes: Oxidative Stress, Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Nitric Oxide Inhibitor
[+]

Astaxanthin may be benefit for prevention and treatment of preeclampsia disease.Sep 30, 2014

Pubmed Data : Yao Xue Xue Bao. 2014 Oct ;49(10):1400-5. PMID: 25577869
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Pre-Eclampsia
Pharmacological Actions : Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Oct ;18(4):2877-2884. Epub 2019 Aug 16. PMID: 31572532
Article Published Date : Sep 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Avocado/soybean unsaponifiables have a protective effect against experimental dog osteoarthritis. Jan 01, 2009

Pubmed Data : Arthritis Res Ther. 2009;11(2):R41. Epub 2009 Mar 16. PMID: 19291317
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Avocado, Soy, Unsaponifiables , Vitamin E
Diseases : Osteoarthritis
Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Baicalein improves learning and memory dysfunction in D-gal induced aging rats.May 25, 2017

Pubmed Data : Rejuvenation Res. 2017 May 26. Epub 2017 May 26. PMID: 28548620
Article Published Date : May 25, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bay leaf contains compounds which inhibit LPS-activated nitric oxide production and which induce heat shock protein. Apr 21, 2000

Pubmed Data : Life Sci. 2000 Apr 21;66(22):2151-7. PMID: 10834299
Article Published Date : Apr 21, 2000
Study Type : Animal Study
Additional Links
Substances : Bay leaf
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Enzyme Inhibitors, Heat Shock Protein Inducer, Nitric Oxide Inhibitor
[+]

Beta-Caryophyllene ameliorates the development of experimental autoimmune encephalomyelitis.Apr 28, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr 29 ;91:257-264. Epub 2017 Apr 29. PMID: 28463791
Article Published Date : Apr 28, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Autoimmune Diseases, Encephalomyelitis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Betulinic acid protects against cerebral ischemia-reperfusion injury.Apr 29, 2011

Pubmed Data : Nitric Oxide. 2011 Apr 30 ;24(3):132-8. Epub 2011 Feb 1. PMID: 21292018
Article Published Date : Apr 29, 2011
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Brain: Oxidative Stress, Brain Ischemia
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Bixa orellana leaves extract inhibits bradykinin-induced inflammation.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Princ Pract. 2011 ;20(2):142-6. Epub 2011 Jan 20. PMID: 21252569
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Achiote
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Boswellia could be considered as a new natural extract to combat heart pathologies, such as autoimmune myocarditis.Oct 27, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Oct 28 ;11(11). Epub 2022 Oct 28. PMID: 36358503
Article Published Date : Oct 27, 2022
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Myocarditis: Autoimmune
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Nrf2 activation
[+]

Boysenberry seed polyphenols have antihypertensive effects.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2012 ;76(9):1694-701. Epub 2012 Sep 7. PMID: 22972352
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berries: All
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Nitric Oxide Inhibitor, Vasodilator Agents
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Camel milk attenuates rheumatoid arthritis in animals. Sep 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 Sep 20 ;43(2):540-552. Epub 2017 Sep 20. PMID: 28930753
Article Published Date : Sep 19, 2017
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.Apr 30, 2013

Pubmed Data : Biochem Pharmacol. 2013 May 1 ;85(9):1306-16. Epub 2013 Feb 12. PMID: 23415610
Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Cannabigerol , Cannabinoids
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Cannabinoids seem to protect neurons against NMDA toxicity.Feb 28, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Pharmacol. 2006 Mar ;69(3):691-6. Epub 2005 Nov 18. PMID: 16299067
Article Published Date : Feb 28, 2006
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Pharmacological Actions : Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Capsaicin affects macrophage anti-inflammatory activity via the MAPK and NF-κB signaling pathways.Jul 07, 2021

Pubmed Data : Int J Vitam Nutr Res. 2021 Jul 8. Epub 2021 Jul 8. PMID: 34235954
Article Published Date : Jul 07, 2021
Study Type : Animal Study
Additional Links
Substances : Capsaicin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carthamus tinctorius extract ameliorated hemodynamic alteration and vascular remodelling in 2K-1C hypertensive rats.Feb 28, 2018

Pubmed Data : Ann Anat. 2018 Mar ;216:82-89. Epub 2017 Dec 20. PMID: 29274384
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Hypertension, Oxidative Stress
Pharmacological Actions : Nitric Oxide Inhibitor, Vasoprotective
Additional Keywords : Plant Extracts
[+]

Chemopreventive efficacy of Andrographis paniculata on azoxymethane-induced aberrant colon crypt foci in vivo.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(11):e111118. Epub 2014 Nov 12. PMID: 25390042
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Andrographis, Flavonoids
Diseases : Colorectal Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Chinese skullcap (Scutellaria baicalensis) significantly improves functional recovery from spinal cord injury in rats by inhibiting inflammation and oxidative stress after injury.Aug 01, 2009

Pubmed Data : J Neurochem. 2009 Aug;110(4):1276-87. Epub 2009 Jun 10. PMID: 19519665
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain: Microglial Activation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Cordyceps militaris could have the protective role from cognitive impairment and progression of Alzheimer's disease.May 31, 2019

Pubmed Data : Food Sci Biotechnol. 2019 Jun ;28(3):865-872. Epub 2018 Dec 4. PMID: 31093445
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Curcumin attenuates ovalbumin-induced airway inflammation.Oct 17, 2008

Pubmed Data : Biochem Biophys Res Commun. 2008 Oct 17;375(2):275-9. Epub 2008 Aug 13. PMID: 18706396
Article Published Date : Oct 17, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Allergic Airway Diseases, Asthma
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Curcumin inhibits nitric oxide production. Jun 15, 1998

Pubmed Data : Biochem Pharmacol. 1998 Jun 15;55(12):1955-62. PMID: 9714315
Article Published Date : Jun 15, 1998
Study Type : Animal Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Curcumin might be useful in the chemoprevention of colorectal cancer in individuals consuming an high-protein diet.Jul 31, 2015

Pubmed Data : Nutr Res. 2015 Aug ;35(8):726-35. Epub 2015 Jun 1. PMID: 26094212
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Colorectal Cancer: Prevention , Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin prevents colon carcinogenesis. Apr 01, 1999

Pubmed Data : Carcinogenesis. 1999 Apr;20(4):641-4. PMID: 10223193
Article Published Date : Apr 01, 1999
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Colon Cancer, Colon Polyps
Pharmacological Actions : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, Enzyme Inhibitors, Nitric Oxide Inhibitor
[+]

Curcumin prevents shock-wave lithotripsy-induced renal injury.Jun 01, 2009

Pubmed Data : Urol Res. 2009 Jun;37(3):159-64. Epub 2009 Apr 2. PMID: 19340419
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Kidney Stones, Shock wave lithotripsy (SWL)-induced damage
Pharmacological Actions : Antioxidants, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.Jan 01, 2009

Pubmed Data : J Exp Biol. 2009 Jan;212(Pt 2):163-8. PMID: 11020339
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Nitric Oxide Inhibitor
[+]

Diallyl sulfide and diallyl disulfide exert therapeutic effects in the DNBS model of colitis.Feb 28, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Mar ;59(3):434-42. Epub 2015 Jan 21. PMID: 25488545
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Diallyl sulfide, Garlic
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor
[+]

Diallyl sulfide may have protective effect on acute lung injury induced by paraquat.Jun 19, 2021

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2021 Jun 20 ;39(6):438-441. PMID: 34218561
Article Published Date : Jun 19, 2021
Study Type : Animal Study
Additional Links
Substances : Diallyl sulfide
Diseases : Lung Damage, Paraquat Toxicity, Pesticide Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
Problem Substances : Paraquat
[+]

Dietary kaempferol suppresses inflammation of dextran sulfate sodium-induced colitis.Jan 31, 2012

Pubmed Data : Dig Dis Sci. 2012 Feb ;57(2):355-63. Epub 2011 Sep 8. PMID: 21901258
Article Published Date : Jan 31, 2012
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Dietary omega-3 fatty acids positively modulate the substrate for post-operative atrial fibrillation in a canine cardiac surgery model.Mar 01, 2011

Pubmed Data : Cardiovasc Res. 2011 Mar 1;89(4):852-61. Epub 2010 Nov 30. PMID: 21123218
Article Published Date : Mar 01, 2011
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Atrial Fibrillation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice.Jan 01, 2010

Pubmed Data : Asia Pac J Clin Nutr. 2010;19(1):142-50. PMID: 20132809
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Inflammation, Ulcerative Colitis
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, P38 Mitogen-Activated Protein Kinase Modulator, Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
[+]

Echinacea extract might reduce the production of proinflammatory cytokines via TLR4 pathways and improve diabetes-induced male infertility.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2021 ;8:651286. Epub 2021 Apr 28. PMID: 33996978
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Diabetic Complications, Infertility: Male
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of cultured Cordycep militaris on sexual performance and erectile function in streptozotocin-induced diabetes.Dec 31, 2019

Pubmed Data : Biomed Res Int. 2020 ;2020:4198397. Epub 2020 Nov 13. PMID: 33274209
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Diabetic Complications, Erectile Dysfunction
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2013 ;77(10):1997-2001. Epub 2013 Oct 7. PMID: 24096647
Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pine Needle
Diseases : Diabetes Mellitus: Type 1, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Nitric Oxide Inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Essential Oils
[+]

Essential oils extracted from Chamaecyparis obtusa may be considered an effective therapeutic agent for the treatment of inflammatory diseases.Mar 31, 2016

Pubmed Data : Mol Med Rep. 2016 Apr ;13(4):3335-41. Epub 2016 Feb 18. PMID: 26936418
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Japanese cypress
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Essential Oils
[+]

Evaluation of data supported the anti-inflammatory activities of thymoquinone, so it may be investigated as an effective anti-inflammatory drug in rheumatoid arthritis.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pak Med Assoc. 2015 May ;65(5):519-25. PMID: 26028387
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Methotrexate
[+]

Evaluation of the cytotoxic, anti-inflammatory, and immunomodulatory effects of withaferin A against lipopolysaccharide-induced inflammation.Jun 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Jun 13 ;14(6). Epub 2022 Jun 13. PMID: 35745829
Article Published Date : Jun 12, 2022
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Extracts of R. officinalis and rosmarinic acid through modulating neuro-inflammation might be potential candidates in treating neuropathic pain.Dec 21, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec 22 ;86:441-449. Epub 2016 Dec 22. PMID: 28012923
Article Published Date : Dec 21, 2016
Study Type : Animal Study
Additional Links
Substances : Rosemary, Rosmarinic acid
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Extremely low frequency electromagnetic fields alter nitric oxide activiy.Oct 26, 1998

Pubmed Data : Brain Res. 1998 Oct 26 ;809(1):50-7. PMID: 9795129
Article Published Date : Oct 26, 1998
Study Type : Animal Study
Additional Links
Pharmacological Actions : Enzyme Inhibitors, Nitric Oxide Inhibitor
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
[+]

Fermented barley extract effectively inhibited the propagation of inflammation by suppressing oxidative stress.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2011 ;75(10):1971-6. Epub 2011 Oct 7. PMID: 21979071
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Barley, Fermented Foods and Beverages
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Fermented C. longa might be a useful material for preventing impairment of learning and memory.Jul 16, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jul 17 ;17(1):367. Epub 2017 Jul 17. PMID: 28716085
Article Published Date : Jul 16, 2017
Study Type : Animal Study
Additional Links
Substances : Turmeric: Fermented
Diseases : Cognitive Decline/Dysfunction, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Fermented soybean has anti-inflammatory properties in the kidney of high-fat-fed rats.Jul 01, 1987

Pubmed Data : J Ethnopharmacol. 1987 Jul;20(2):85-106. PMID: 21332402
Article Published Date : Jul 01, 1987
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Soy, Soy: Fermented
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Vascular Cell Adhesion Molecule-1 Inhibitor
[+]

Genipin inhibited LPS-induced inflammatory response by activating Nrf2 signalling pathway in BV2 microglia.Sep 30, 2017

Pubmed Data : Neurochem Res. 2017 Oct ;42(10):2769-2776. Epub 2017 May 11. PMID: 28497344
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginger inhibits micoglial cell activiation associated with brain inflammation. Jun 01, 2009

Pubmed Data : Food Chem Toxicol. 2009 Jun;47(6):1190-7. Epub 2009 Feb 20. PMID: 19233241
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Brain: Microglial Activation, Brain Inflammation , Inflammation, Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin Antagonists
[+]

Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Oct ;16(4):3020-3026. Epub 2018 Jul 26. PMID: 30214520
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats.Feb 28, 2015

Pubmed Data : J Sex Med. 2015 Mar ;12(3):611-20. Epub 2014 Dec 1. PMID: 25442300
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetic Complications, Erectile Dysfunction
Pharmacological Actions : Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Grape seed proanthocyanidin extract alleviates urethral dysfunction in diabetic rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Jan ;15(1):1053-1061. Epub 2017 Nov 13. PMID: 29403553
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Diabetic Complications
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor, Nrf2 activation
Additional Keywords : Proanthocyanidins
[+]

Gypenosides attenuated cholesterol induced DNA damage by inhibiting ROS production.Mar 31, 2015

Pubmed Data : Mol Med Rep. 2015 Apr ;11(4):2845-51. Epub 2014 Dec 16. PMID: 25515035
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Gynostemma
Diseases : DNA damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Hepatoprotective effect and potential mechanism of aqueous extract from Phyllanthus emblica on carbon-tetrachloride-induced liver fibrosis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:5345821. Epub 2021 Oct 19. PMID: 34712342
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Indian Gooseberry
Diseases : Liver Fibrosis
Pharmacological Actions : Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hesperidin might improve the endothelium-dependent vasodilation during hypertension.Sep 30, 2016

Pubmed Data : Phytother Res. 2016 Oct ;30(10):1665-1671. Epub 2016 Jul 1. PMID: 27363952
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Endothelial Dysfunction, Hypertension
Pharmacological Actions : Nitric Oxide Inhibitor, Vasodilator Agents
[+]

Honey has anti-inflammatory properties likely due to its nitric oxide inhibitory properties. Apr 01, 2011

Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2011 Apr ;9(4):447-52. PMID: 21486559
Article Published Date : Apr 01, 2011
Study Type : Animal Study
Additional Links
Substances : Honey
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Inhibitory activities of rare ginsenoside Rg4 on cecal ligation and puncture-induced sepsis.Sep 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Sep 16 ;23(18). Epub 2022 Sep 16. PMID: 36142743
Article Published Date : Sep 15, 2022
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Inflammation, Kidney Damage, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Intranasal curcumin alleviate paraquat induced pulmonary damage and pro-inflammatory cytokine levels like tumor necrosis factor-α (TNF-α) and nitric oxide (NO).Oct 31, 2014

Pubmed Data : Environ Toxicol Pharmacol. 2014 Nov ;38(3):913-21. Epub 2014 Oct 18. PMID: 25461551
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Herbicide Toxicity, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(9):e0184709. Epub 2017 Sep 18. PMID: 28922365
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Isothiocyanates, Moringa oleifera
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Kefir modulates gut microbiota and reduces DMH-associated colorectal cancer.Jan 31, 2022

Pubmed Data : Food Res Int. 2022 Feb ;152:110708. Epub 2021 Sep 8. PMID: 35181109
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-arginine may ameliorate gastrointestinal dysfunction in diabetic rats.Mar 01, 2009

Pubmed Data : Nitric Oxide. 2009 Mar;20(2):129-33. Epub 2008 Nov 18. PMID: 19041728
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Diabetes: Gastrointestinal dysfunction
Pharmacological Actions : Enzyme Inhibitors, Nitric Oxide Inhibitor
[+]

L-arginine reduces mercury accumulation in thymus of mercury-exposed mice.Dec 01, 2008

Pubmed Data : Ind Health. 2008 Dec;46(6):567-74. PMID: 19088408
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Mercury Poisoning
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

L-arginine supplementation reduces cardiac noradrenergic neurotransmission in spontaneously hypertensive rats. Jul 01, 2009

Pubmed Data : J Mol Cell Cardiol. 2009 Jul;47(1):149-55. Epub 2009 Apr 9. PMID: 19362092
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Cardiac noradrenergic hyperactivity , Hypertension
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

l-Theanine improves functional recovery after traumatic spinal cord injury in rats.Dec 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Formos Med Assoc. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31812333
Article Published Date : Dec 04, 2019
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

L0arginine supplementation improves endothelial function and myocardial perfusion in a swine model of chronic myocardial ischemia.Aug 01, 2005

Pubmed Data : Surgery. 2005 Aug;138(2):291-8. PMID: 16153439
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Coronary Artery Disease, Endothelial Dysfunction, High Cholesterol, Myocardial Ischemia
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Lotus has immunomodulatory effects. Jan 05, 2010

Pubmed Data : Psychol Med. 2010 Jan 5:1-11. Epub 2010 Jan 5. PMID: 20095810
Article Published Date : Jan 05, 2010
Study Type : Animal Study
Additional Links
Substances : Lotus
Pharmacological Actions : Histamine Antagonists, Immunomodulatory, Nitric Oxide Inhibitor
[+]

Luteolin alleviates cognitive impairment in Alzheimer's disease model.Jul 14, 2021

Pubmed Data : Acta Pharmacol Sin. 2021 Jul 15. Epub 2021 Jul 15. PMID: 34267346
Article Published Date : Jul 14, 2021
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Memory enhancing effect of Nigella Sativa hydro-alcoholic extract on lipopolysaccharide-induced memory impairment.Mar 27, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Mar 28:1-10. Epub 2018 Mar 28. PMID: 29589766
Article Published Date : Mar 27, 2018
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

N. sativa could be used in the treatment of rhinosinusitis diseases.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Otorhinolaryngol Ital. 2017 Feb ;37(1):32-37. PMID: 28374868
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Rhinosinusitis
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Naringin protects viscera from ischemia/reperfusion injury by regulating the nitric oxide level in a rat model.Dec 31, 2016

Pubmed Data : Biotech Histochem. 2017 ;92(4):252-263. Epub 2017 Apr 20. PMID: 28426254
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Ischemia
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Nettle extract might prove to be effective for stress mediated neurological disorders.Jul 27, 2016

Pubmed Data : Biomed Pharmacother. 2016 Jul 28 ;83:676-686. Epub 2016 Jul 28. PMID: 27470568
Article Published Date : Jul 27, 2016
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Cognitive Decline/Dysfunction, Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats.Oct 23, 2020

Pubmed Data : Clin Exp Pharmacol Physiol. 2020 Oct 24. Epub 2020 Oct 24. PMID: 33098686
Article Published Date : Oct 23, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Niacin could effectively attenuate the over expression of nitric oxide synthase in the rat lung induced by silica particles. May 01, 2004

Pubmed Data : Zhonghua Yu Fang Yi Xue Za Zhi. 2004 May;38(3):186-9. PMID: 15182488
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Pulmonary Fibrosis
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Nigella sativa oil appears to have a therapeutic potential in opioid tolerance and dependence.Sep 30, 2010

Pubmed Data : Neurochem Res. 2010 Oct ;35(10):1557-65. Epub 2010 Jun 15. PMID: 20552271
Article Published Date : Sep 30, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Morphine Tolerance/Dependence, Oxidative Stress
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Plant Oils
[+]

Noni, and its major bioactive component damnacanthal, exhibits anti-inflammatory properties. Nov 01, 2011

Pubmed Data : Inflamm Allergy Drug Targets. 2011 Nov 1. Epub 2011 Nov 1. PMID: 21999179
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Substances : Damnacanthal, Noni
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res. 2014 Jul ;34(7):595-603. Epub 2014 Jun 14. PMID: 25150118
Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee
Diseases : Lipid Peroxidation, Memory Disorders
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Antioxidants, Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy, Plant Extracts
[+]

Oral tangeretin treatment effectively reduced the tumor cell proliferation markers and suppressed metastasis. Oct 31, 2014

Pubmed Data : J Nutr Biochem. 2014 Nov ;25(11):1140-53. Epub 2014 Aug 1. PMID: 25151216
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Breast Cancer, Breast Cancer: Metastatic
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Chemotherapeutic, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor
[+]

Paeonol may be a potential therapeutic agent in the treatment of osteoarthritis.Sep 30, 2017

Pubmed Data : Inflammation. 2017 Oct ;40(5):1698-1706. PMID: 28695367
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Paeonol
Diseases : Osteoarthritis
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stressOct 31, 2016

Pubmed Data : Pharmacol Res. 2016 Nov ;113(Pt A):276-289. Epub 2016 Sep 8. PMID: 27616549
Article Published Date : Oct 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Panax ginseng anthocyanins pre-administration can significantly prevent cisplatin-induced nephrotoxicity.Jul 20, 2017

Pubmed Data : Phytother Res. 2017 Jul 21. Epub 2017 Jul 21. PMID: 28731262
Article Published Date : Jul 20, 2017
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Panax Ginseng
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Anthocyanins, Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, Panax Ginseng
[+]

Panax notoginseng saponins modulate the inflammatory response and improve IBD-like symptoms.Apr 06, 2021

Pubmed Data : Am J Chin Med. 2021 Apr 7:1-15. Epub 2021 Apr 7. PMID: 33829964
Article Published Date : Apr 06, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor
[+]

Patchouli may provide gastrointestinal protection against trauma or surgical operation. Jul 01, 2009

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Jul;29(7):639-41. PMID: 19852300
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Bowel Surgery, Colon Surgery, Gastrointestinal Diseases, Short Bowel Syndrome
Pharmacological Actions : Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Perilla frutescens and its active compound rosmarinic acid have beneficial effects on cognitive improvement and may help prevent Alzheimer's disease.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2016 Jun ;10(3):274-81. Epub 2016 Apr 1. PMID: 27247723
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Phloretin may be a potential agent for the treatment of osteoarthritis.Nov 22, 2017

Pubmed Data : Food Funct. 2017 Nov 23. Epub 2017 Nov 23. PMID: 29168867
Article Published Date : Nov 22, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phloretin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Polysaccharide from the seeds of Plantago asiatica L. protect against lipopolysaccharide-induced liver injury.Sep 26, 2019

Pubmed Data : J Med Food. 2019 Sep 27. Epub 2019 Sep 27. PMID: 31560611
Article Published Date : Sep 26, 2019
Study Type : Animal Study
Additional Links
Substances : Plantago asiatica
Diseases : Chemically-Induced Liver Damage, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Hepatoprotective, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Polysaccharides derived from Morinda citrifolia Linn reduce inflammatory markers during experimental colitis.Oct 11, 2019

Pubmed Data : J Ethnopharmacol. 2019 Oct 12 ;248:112303. Epub 2019 Oct 12. PMID: 31614204
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
Additional Keywords : Polysaccharides
[+]

Portulaca oleracea extract had protective effects on acute alcoholic liver injury.Aug 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Aug 8 ;24(16). Epub 2019 Aug 8. PMID: 31398934
Article Published Date : Aug 07, 2019
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Propolis may constitute a potential candidate to modulate inflammation during Celiac disease and has a potential therapeutic value.Mar 06, 2018

Pubmed Data : Inflammopharmacology. 2018 Mar 7. Epub 2018 Mar 7. PMID: 29516252
Article Published Date : Mar 06, 2018
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Celiac Disease
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Nitric Oxide Inhibitor
[+]

Propolis modulates NOS2/arginase-1 pathway in tropomyosin-induced experimental autoimmune uveitis.May 10, 2018

Pubmed Data : Inflammopharmacology. 2018 May 11. Epub 2018 May 11. PMID: 29752572
Article Published Date : May 10, 2018
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Uveitis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of bilobalide on learning and memory impairment in rats with vascular dementia.Aug 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2013 Sep ;8(3):935-41. Epub 2013 Jul 8. PMID: 23835946
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Dementia
Pharmacological Actions : Anti-Apoptotic, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of carotenoid extract from orange-fleshed sweet potato on gastric ulcer.Dec 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Dec 17 ;14(12). Epub 2021 Dec 17. PMID: 34959718
Article Published Date : Dec 16, 2021
Study Type : Animal Study
Additional Links
Substances : Sweet Potato
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Gastroprotective, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Protective effect of Cordyceps sinensis extract on lipopolysaccharide-induced acute lung injury.Jun 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2019 Jun 28 ;39(6). Epub 2019 Jun 25. PMID: 31186277
Article Published Date : Jun 27, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of bilobalide on Aβ(25-35) induced learning and memory impairments in male rats.Apr 30, 2013

Pubmed Data : Pharmacol Biochem Behav. 2013 May ;106:77-84. Epub 2013 Mar 26. PMID: 23537729
Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Alzheimer's Disease, Memory Disorders
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of hydroalcoholic extract of Rosa canina fruit on vancomycin-induced nephrotoxicity.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2021 ;2021:5525714. Epub 2021 May 28. PMID: 34135957
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Kidney Damage: Chemically-Induced
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Renoprotective
[+]

Protective effects of Phyllanthus amarus against lipopolysaccharide-induced neuroinflammation and cognitive impairment.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:632. Epub 2019 Jun 4. PMID: 31231221
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Phyllanthus amarus
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin exerts antipyretic effect on lipopolysaccharide-induced fever.May 06, 2012

Pubmed Data : J Ethnopharmacol. 2012 May 7 ;141(1):322-30. Epub 2012 Feb 28. PMID: 22401764
Article Published Date : May 06, 2012
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Fever, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Anti-pyretic , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy
[+]

Red wine and black tea and polyphenolic extracts modulate COX-2, iNOS and GSH-related gene expression in tumors, suggesting also a possible chemotherapeutic activity of these compounds.May 31, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2002 Jun ;132(6):1376-9. PMID: 12042461
Article Published Date : May 31, 2002
Study Type : Animal Study
Additional Links
Substances : Black Tea, Polyphenols, Red Wine
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemotherapeutic, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Renal protective effects of aspalathin and nothofagin from rooibos in a sepsis model.Nov 30, 2018

Pubmed Data : Pharmacol Rep. 2018 Dec ;70(6):1195-1201. Epub 2018 Jul 27. PMID: 30340097
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Kidney Damage, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol and curcumin may combine with insulin in attenuating diabetic neuropathic pain.Mar 01, 2007

Pubmed Data : Phytother Res. 2007 Mar;21(3):278-83. PMID: 17199240
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Diabetic Neuropathies, Pain
Pharmacological Actions : Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts, Stilbenes
[+]

Resveratrol and piceatannol inhibit inflammation in a mouse model of colitis. Jan 01, 2009

Pubmed Data : Nutr Cancer. 2009;61(6):847-54. PMID: 20155626
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Piceatannol , Resveratrol, Stilbenes
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Extracellular Signal-Regulated Kinases Modulator, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, STAT3 Inhibitor
[+]

Resveratrol and quercetin exert both indirect and direct vasodilator effects on the blood vessel by nitric oxide-mediated and non-NO-mediated mechanisms.Mar 01, 1996

Pubmed Data : Gen Pharmacol. 1996 Mar;27(2):363-6. PMID: 8919657
Article Published Date : Mar 01, 1996
Study Type : Animal Study
Additional Links
Substances : Quercetin, Resveratrol, Stilbenes
Diseases : Endothelial Dysfunction
Pharmacological Actions : Enzyme Inhibitors, Nitric Oxide Inhibitor, Vasodilator Agents
[+]

Resveratrol has a protective effect on acute lung injury induced by lipopolysaccharide in mice.Mar 01, 2011

Pubmed Data : Anat Rec (Hoboken). 2011 Mar;294(3):527-32. Epub 2011 Jan 31. PMID: 21284090
Article Published Date : Mar 01, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Infection, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor
[+]

Resveratrol inhibits restenosis in an animal model. Nov 01, 2010

Pubmed Data : Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1451-8. Epub 2010 Aug 13. PMID: 20709862
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Restenosis
Pharmacological Actions : Antiproliferative , Enzyme Inhibitors, Estrogen Receptor Modulators, Nitric Oxide Inhibitor
Additional Keywords : Stilbenes
[+]

Resveratrol may have a therapeutic role in retinopathy of prematurity.Apr 01, 2010

Pubmed Data : Korean J Ophthalmol. 2010 Apr;24(2):108-18. Epub 2010 Apr 6. PMID: 20379461
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Retinal Detachment, Retinopathy of Prematurity
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Stilbenes
[+]

Resveratrol, a red wine polyphenol, attenuates lipopolysaccharide-induced oxidative stress in rat liver.Jul 01, 2010

Pubmed Data : Ecotoxicol Environ Saf. 2010 Jul;73(5):1078-83. Epub 2010 Jan 20. PMID: 20089305
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Endotoxemia, Lipid Peroxidation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
[+]

Rosa damascena restrains Plasmodium falciparum progression in vitro and impedes malaria pathogenesis in murine model.Dec 31, 2017

Pubmed Data : Biomed Pharmacother. 2018 Jan ;97:1654-1662. Epub 2017 Dec 8. PMID: 29793328
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rose
Diseases : Malaria, Plasmodium Infections
Pharmacological Actions : Anti-Inflammatory Agents, Antimalarials, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in rats.Jul 23, 2021

Pubmed Data : J Chem Neuroanat. 2021 Jul 24 ;117:102008. Epub 2021 Jul 24. PMID: 34314849
Article Published Date : Jul 23, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rutin inhibited the advanced glycation end products-stimulated inflammatory response and extra-cellular matrix degeneration.Jan 21, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2021 09 22 ;13(18):22134-22147. Epub 2021 Sep 22. PMID: 34550907
Article Published Date : Jan 21, 2021
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Advanced Glycation End products (AGE), Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rutin inhibits nitric oxide and tumor necrosis factor-alpha production in lipopolysaccharide and concanavalin-a stimulated macrophages.Jan 01, 2007

Pubmed Data : Drug Metabol Drug Interact. 2007;22(4):263-78. PMID: 18447002
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Rutin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Safranal pretreatment to these allergically inflamed mice lead to a significant decrease in airway hyper-responsiveness and airway cellular infiltration to the lungs.Mar 31, 2015

Pubmed Data : Phytother Res. 2015 Apr ;29(4):617-27. Epub 2015 Mar 10. PMID: 25756352
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Asthma
Pharmacological Actions : Anti-Apoptotic, Anti-Asthmatic Agents, Nitric Oxide Inhibitor
[+]

Sambucus nigra: A traditional medicine effective in reducing inflammation.Jan 29, 2022

Pubmed Data : J Ethnopharmacol. 2022 Jan 30 ;283:114736. Epub 2021 Oct 11. PMID: 34648899
Article Published Date : Jan 29, 2022
Study Type : Animal Study
Additional Links
Substances : Elderberry
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sesamol has neuroprotective properties. Jun 01, 2011

Pubmed Data : Eur J Pharmacol. 2011 Jun 1 ;659(2-3):177-86. Epub 2011 Apr 2. PMID: 21463622
Article Published Date : Jun 01, 2011
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Brain Damage, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Enzyme Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Shoumei polyphenols are high-quality natural products with liver-protective effects.Dec 31, 2019

Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:9329356. Epub 2020 Aug 19. PMID: 32922655
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Polyphenols, White Tea
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Hepatoprotective, Interleukin-12 downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:314-321. Epub 2018 Nov 3. PMID: 30396089
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Aspirin-Induced Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Gastroprotective, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aspirin
[+]

Spirulina platensis alone or in combination with vitamin c minimized the nephrotoxic effects of amikacin.Jan 25, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Jan 26. Epub 2019 Jan 26. PMID: 30685861
Article Published Date : Jan 25, 2019
Study Type : Animal Study
Additional Links
Substances : Spirulina, Vitamin C
Diseases : Antibiotic Toxicity , Kidney Damage: Antibiotic-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Antibiotics
[+]

Sulforaphane elicits antioxidant, anti-inflammatory, and extracellular matrix remodelling effects in a rat model of diabetic peripheral neuropathy.Aug 01, 2018

Pubmed Data : Inflammation. 2018 Aug ;41(4):1460-1476. PMID: 29704151
Article Published Date : Aug 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Malonaldehyde (MDA) Down-Regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Neuroprotective Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates
[+]

Sulforaphane's anti-inflammatory, antioxidant, and neuroprotective benefits attentuate autoimmune encephalomyelitis in an animal model of Multiple Sclerosis.Jul 22, 2019

Pubmed Data : J Korean Med Sci. 2019 Jul 22 ;34(28):e197. Epub 2019 Jul 22. PMID: 31327180
Article Published Date : Jul 22, 2019
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Autoimmune Diseases, Multiple Sclerosis
Therapeutic Actions : anti-inflammatory, antioxidant, neuro-protective
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Antioxidant, Autoimmune Diseases, Cruciferous Vegetables, Multiple Sclerosis, Phytotherapy, Sulforaphane
[+]

Supplemental L-arginine enhances wound healing in diabetic rats.May 01, 2003

Pubmed Data : Wound Repair Regen. 2003 May-Jun;11(3):198-203. PMID: 12753601
Article Published Date : May 01, 2003
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Wound Healing
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Systemic and topical Ginkgo biloba leaf extract (Egb-761) ameliorated rat paw inflammation in comparison to dexamethasone.Sep 10, 2021

Pubmed Data : J Ethnopharmacol. 2021 Sep 11 ;282:114619. Epub 2021 Sep 11. PMID: 34520829
Article Published Date : Sep 10, 2021
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tangerine peel possesses potent anti-neuroinflammatory capacity which is attributed to the collective effect of hesperidin, nobiletin, and tangeretin.Aug 31, 2014

Pubmed Data : Food Chem Toxicol. 2014 Sep ;71:176-82. Epub 2014 Jun 20. PMID: 24955543
Article Published Date : Aug 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus Peel , Hesperidin, Nobiletin , Tangeretin
Diseases : Brain Inflammation , Inflammation, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

The aerial parts of barley are useful as functional food to prevent acute inflammatory responses.Jul 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2013 Aug ;51(8):1066-76. Epub 2013 Jun 7. PMID: 23746221
Article Published Date : Jul 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Barley
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

The ameliorative effect of berberine and coenzyme Q10 in an ovalbumin-induced allergic rhinitis model.Sep 30, 2018

Pubmed Data : Eur Arch Otorhinolaryngol. 2018 Oct ;275(10):2495-2505. Epub 2018 Aug 23. PMID: 30159729
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine, Coenzyme Q10
Diseases : Allergic Rhinitis
Pharmacological Actions : interleukin-13 down-regulation, Interleukin-4 downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
[+]

The flower extract of Rosa rugosa may be a beneficial anti-inflammatory agent.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2016 Mar 1 ;24(2):184-90. PMID: 26797110
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

The hepato-renal protective potential of walnut seed skin extract against acute renal ischemia/reperfusion damage.Apr 30, 2022

Pubmed Data : Cytokine. 2022 May ;153:155861. Epub 2022 Mar 18. PMID: 35306426
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Kidney Damage, Liver Damage, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

The results indicate a potential for therapeutic use of cannabidiol in chronic painful states.Feb 04, 2007

Pubmed Data : Eur J Pharmacol. 2007 Feb 5 ;556(1-3):75-83. Epub 2006 Nov 10. PMID: 17157290
Article Published Date : Feb 04, 2007
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Hyperalgesia, Inflammation, Neuropathic Pain
Pharmacological Actions : NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Therapeutic effect of carvacrol-loaded albumin nanoparticles on rheumatoid arthritis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2020 ;19(1):312-320. PMID: 32922489
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Nitric Oxide Inhibitor
[+]

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.Feb 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Feb 20 ;7:42995. Epub 2017 Feb 20. PMID: 28216638
Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation, Interleukin-1 beta downregulation, thymoquinone
[+]

These findings suggest that grape seed proanthocyanidin extract has a potential protective effect against DSS-induced ulcerative colitis.Jun 08, 2022

Pubmed Data : Curr Drug Metab. 2022 Jun 9. Epub 2022 Jun 9. PMID: 35692132
Article Published Date : Jun 08, 2022
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract, Proanthocyanidins
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These findings suggest that quercetin exhibits a protective effect in STZ-induced hyperglycemic AA broilers via decreasing oxidative stress.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:9585047. Epub 2020 Feb 10. PMID: 32104545
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Diabetes: Oxidative Stress, Hyperglycemia
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
[+]

These results may point to noni fruit as an important source of anti-inflammatory molecules.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2017 ;2017:6567432. Epub 2017 Jan 17. PMID: 28194046
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

These results suggest that the extract of R. R. laevigata offered good efficacy for preventing liver injury.Apr 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2009 May ;73(5):1129-36. Epub 2009 May 7. PMID: 19420718
Article Published Date : Apr 30, 2009
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

These results validate the use of saffron as a treatment against diabetes mellitus and its vascular complications.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian Heart J. 2017 Mar - Apr;69(2):151-159. Epub 2016 Sep 25. PMID: 28460761
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Diabetic Complications
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hypoglycemic Agents, Hypolipidemic, Immunomodulatory, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

This research suggested that magnolol possessed a new therapeutic potential for the development of osteoarthritis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:393. Epub 2019 Apr 16. PMID: 31040782
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study indicates that a methanol extract from Inonotus obliquus has anti-inflammatory and anti-nociceptive properties.Oct 02, 2005

Pubmed Data : J Ethnopharmacol. 2005 Oct 3 ;101(1-3):120-8. PMID: 15905055
Article Published Date : Oct 02, 2005
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antinoceceptive , Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study shows that diosmetin protects against renal injury in STZ-induced diabetic nephropathy.Oct 01, 2018

Pubmed Data : Med Sci Monit. 2018 Oct 2 ;24:7007-7014. Epub 2018 Oct 2. PMID: 30278036
Article Published Date : Oct 01, 2018
Study Type : Animal Study
Additional Links
Substances : Diosmetin
Diseases : Diabetic Nephropathy
Pharmacological Actions : NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Renoprotective
[+]

This suggests that Perilla frutescens leaf can counteract vascular dementia-associated structural and functional deterioration.Jan 07, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Issues Mol Biol. 2022 Jan 8 ;44(1):257-272. Epub 2022 Jan 8. PMID: 35723398
Article Published Date : Jan 07, 2022
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Brain Inflammation , Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone could protect of the kidneys against damage due to morphine toxicity.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Kidney Dis. 2017 Mar ;11(2):142-150. PMID: 28270647
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Kidney Damage: Drug-Induced
Pharmacological Actions : Anti-Apoptotic, Nitric Oxide Inhibitor, Renoprotective
Problem Substances : Morphine
[+]

Thymoquinone improved lipopolysaccharide induced learning and memory impairments induced by LPS.Apr 18, 2017

Pubmed Data : Cytokine. 2017 Apr 19 ;96:173-184. Epub 2017 Apr 19. PMID: 28432986
Article Published Date : Apr 18, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone prevents sequels of the multiple organ failure syndrome of sepsis by modulating the production of NO and its inflammatory sequela.Aug 14, 2015

Pubmed Data : Life Sci. 2015 Aug 15. Epub 2015 Aug 15. PMID: 26285172
Article Published Date : Aug 14, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 alpha downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Total flavonoids found in black mulberry possess anti-inflammatory and analgesic effects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(4):e0153080. Epub 2016 Apr 5. PMID: 27046026
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Mulberry
Diseases : Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Treatment with taraxasterol significantly increased the pain thresholds and reduced the clinical arthritic scores of mice.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):4035-4040. Epub 2016 Nov 2. PMID: 28101182
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Urolithin A may be adopted as a new therapeutic agent for the treatment of osteoarthritis.Sep 08, 2019

Pubmed Data : Food Funct. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31497826
Article Published Date : Sep 08, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Urolithin A
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Virgin coconut oil has the potential to be used as a memory enhancer.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2017 Dec ;55(1):825-832. PMID: 28118770
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Virgin Coconut Oil
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Down-Regulation, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke.Feb 28, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar ;99:583-590. Epub 2018 Feb 20. PMID: 29710456
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Autophagy Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Z. multiflora ameliorated learning and memory dysfunction in LPS - challenged rats.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet Res Forum. 2022 Mar ;13(1):101-110. Epub 2022 Mar 15. PMID: 35601788
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Zataria multiflora
Diseases : Learning disorders, Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Z. multiflora essential oil has the potential to be used in the therapy of oxidative damage.Sep 30, 2012

Pubmed Data : J Pharm Pharmacol. 2012 Oct ;64(10):1491-500. Epub 2012 Apr 5. PMID: 22943180
Article Published Date : Sep 30, 2012
Study Type : Animal Study
Additional Links
Substances : Zataria multiflora
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
Additional Keywords : Essential Oils, Plant Extracts
[+]

β-glucans from Lentinus edodes could inhibit the DSS-induced ulcerative colitis and decrease inflammatory factor expressions.Nov 08, 2016

Pubmed Data : Food Funct. 2016 Nov 9 ;7(11):4614-4627. PMID: 27747357
Article Published Date : Nov 08, 2016
Study Type : Animal Study
Additional Links
Substances : Shiitake Mushroom
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

β-patchoulene isolated from patchouli oil had Anti-inflammatory activity.Apr 13, 2016

Pubmed Data : Eur J Pharmacol. 2016 Apr 14. Epub 2016 Apr 14. PMID: 27090925
Article Published Date : Apr 13, 2016
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Oils
[+]

Oridonin inhibits LPS-induced inflammation in human gingival fibroblasts by activating PPARγ.Jun 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jul ;72:301-307. Epub 2019 Apr 18. PMID: 31005040
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

A comparative study on hulled adlay and unhulled adlay through evaluation of their LPS-induced anti-inflammatory effects.Feb 28, 2015

Pubmed Data : Chem Biodivers. 2015 Mar ;12(3):380-7. PMID: 25766911
Article Published Date : Feb 28, 2015
Study Type : In Vitro Study
Additional Links
Substances : Adlay
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

A. arguta stem extracts could be useful in preventing inflammation mediated diseases.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2014 Dec ;21(6):532-8. Epub 2014 Feb 4. PMID: 25473361
Article Published Date : Nov 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kiwifruit
Diseases : Hypoglycemia, Inflammation
Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Hypoglycemic Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Achillea fragrantissima possesses anti-neuroinflammatory activities for prevention or treatment of neurodegenerative diseases.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2011 ;11:98. Epub 2011 Oct 21. PMID: 22018032
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Achillea fragrantissima
Diseases : Brain: Microglial Activation, Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Aged red garlic extract may enhance anti-inflammatory effects by controlling other anti-inflammatory signals as well as regulation of NF-κB.Mar 31, 2015

Pubmed Data : J Med Food. 2015 Apr ;18(4):439-45. Epub 2015 Jan 13. PMID: 25584924
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Alantolactone may provide a useful therapeutic approach for inflammation-associated diseases. Nov 30, 2012

Pubmed Data : Int Immunopharmacol. 2012 Dec ;14(4):375-83. Epub 2012 Aug 28. PMID: 22940184
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells.Jan 31, 2011

Pubmed Data : Neurochem Int. 2011 Feb ;58(2):153-60. Epub 2010 Nov 18. PMID: 21093515
Article Published Date : Jan 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory and cytotoxic activities of constituents isolated from the fruits of Ziziphus jujuba var. inermis Rehder.Jul 04, 2019

Pubmed Data : Fitoterapia. 2019 Jul 5 ;137:104261. Epub 2019 Jul 5. PMID: 31284019
Article Published Date : Jul 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Jujube
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Cytotoxic, Nitric Oxide Inhibitor
[+]

Anti-inflammatory effects of fucoxanthinol in LPS-induced RAW264.7 cells.Apr 20, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2020 Apr 21 ;18(4). Epub 2020 Apr 21. PMID: 32326173
Article Published Date : Apr 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carotenoids
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects of ginsenoside-Rh2 inhibits LPS-induced activation of microglia and overproduction of inflammatory mediators.Apr 30, 2016

Pubmed Data : Neurochem Res. 2016 May ;41(5):951-7. Epub 2016 Jan 6. PMID: 26738987
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Brain: Microglial Activation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects of heliangin from Jerusalem artichoke leaves might prevent atherosclerosis.Jan 05, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 01 6 ;12(1). Epub 2022 Jan 6. PMID: 35053238
Article Published Date : Jan 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Anti-inflammatory effects of Morinda citrifolia extract against lipopolysaccharide-induced inflammation in RAW264 cells.Aug 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2021 Aug 4 ;8(8). Epub 2021 Aug 4. PMID: 34436222
Article Published Date : Aug 03, 2021
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Anti-inflammatory property of the ethanol extract of the root and rhizome of Pogostemon cablin.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2013 ;2013:434151. Epub 2013 Dec 9. PMID: 24385881
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Patchouli
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Anti-neuroinflammatory of chloroform extract of Panax ginseng root culture on lipopolysaccharide-stimulated BV2 microglia cells.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rep Biochem Mol Biol. 2022 Apr ;11(1):125-137. PMID: 35765526
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Ginseng
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arginine may be beneficial for ameliorating vascular insulin resistance in obesity and diabetes.Jan 01, 2009

Pubmed Data : Biofactors. 2009 Jan-Feb;35(1):21-7. PMID: 19319842
Article Published Date : Jan 01, 2009
Study Type : Review
Additional Links
Substances : Arginine
Diseases : Diabetes Mellitus: Type 2, Endothelial Dysfunction, Insulin Resistance, Obesity
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Arginine may play a role in ameliorating scurvy. Jan 01, 2009

Pubmed Data : J Ethnobiol Ethnomed. 2009;5:5. Epub 2009 Feb 2. PMID: 19187550
Article Published Date : Jan 01, 2009
Study Type : Review
Additional Links
Substances : Arginine, Vitamin C
Diseases : Scurvy
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Assessment of anti-inflammatory and antioxidant effects of Citrus unshiu peel flavonoids on LPS-stimulated RAW 264.7 cells.Oct 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Oct 18 ;10(10). Epub 2021 Oct 18. PMID: 34686018
Article Published Date : Oct 17, 2021
Study Type : In Vitro Study
Additional Links
Substances : Orange: Mandarin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein, wogonin, and oroxylin A can effectively relieve Aβ25-35-stimulated neuronal apoptosis and inflammation.Nov 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 2 ;25(21). Epub 2020 Nov 2. PMID: 33147823
Article Published Date : Nov 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Baicalein, Wogonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bay leaf contains compounds capable of inhibiting nitric oxide formation. Dec 15, 2004

Pubmed Data : J Agric Food Chem. 2004 Dec 15;52(25):7525-31. PMID: 15675799
Article Published Date : Dec 15, 2004
Study Type : In Vitro Study
Additional Links
Substances : Bay leaf
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Bay leaf has nitric oxide inhibitory properties.Aug 01, 2005

Pubmed Data : Planta Med. 2005 Aug;71(8):706-10. PMID: 16142632
Article Published Date : Aug 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Bay leaf
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

C. vulgaris possesses significant anti-inflammatory activity and could be a potential anti-inflammatory agent of natural origin.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2016 Apr-Jun;8(2):118-22. PMID: 27034602
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Capuli extract attenuated the LPS-induced damage in RAW 264.7 macrophages due to its antioxidant and anti-inflammatory properties.Mar 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Apr ;102:46-52. Epub 2017 Jan 28. PMID: 28137607
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cherry: All Varieties
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Carrot essential oil had significant activity towards the inhibition of Gram-positive bacteria.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:9045196. Epub 2016 Feb 14. PMID: 26981143
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Carrot
Diseases : Candida Albicans, Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Nitric Oxide Inhibitor
Additional Keywords : Biofilm, Essential Oils
[+]

Characterization of the changes in eicosanoid profiles of activated macrophages treated with 20(S)-ginsenoside Rg3.Oct 14, 2017

Pubmed Data : J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Oct 15 ;1065-1066:14-19. Epub 2017 Sep 5. PMID: 28938131
Article Published Date : Oct 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cocoa polyphenolic extracts may be used for the treatment of inflammation and it's related-diseases.Dec 31, 2015

Pubmed Data : Springerplus. 2016;5:547. Epub 2016 Apr 28. PMID: 27190746
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cocoa
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Antioxidants, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:963662. Epub 2022 Sep 8. PMID: 36159482
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Orange
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Compounds from turmeric showed potent inhibitory activity against nitric oxide production.Jul 19, 2017

Pubmed Data : Nat Prod Res. 2017 Jul 20:1-6. Epub 2017 Jul 20. PMID: 28726500
Article Published Date : Jul 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Turmeric
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Crescentia alata exhibits anti-inflammatory properties confirming its traditional use in Guatemala herbalism. Dec 21, 2001

Pubmed Data : Life Sci. 2001 Dec 21;70(5):523-34. PMID: 11811897
Article Published Date : Dec 21, 2001
Study Type : In Vitro Study
Additional Links
Substances : Crescentia Alata
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Enzyme Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts, Science Confirms Tradition
[+]

Crocus sativus and its petal flavonoid showed relatively potent therapeutic effects on respiratory disorders.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2020 Dec ;58(1):1140-1149. PMID: 33295229
Article Published Date : Nov 30, 2020
Study Type : Review
Additional Links
Substances : Kaempferol, Saffron
Diseases : Respiratory Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Crocus sativus L. petal extract inhibits inflammation and osteoclastogenesis in RAW 264.7 cell model.Jun 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Jun 17 ;14(6). Epub 2022 Jun 17. PMID: 35745865
Article Published Date : Jun 16, 2022
Study Type : In Vitro Study
Additional Links
Substances : Saffron
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor
[+]

Cucurbitacin B possesses immunomodulatory and anti-inflammatory effects.Dec 31, 2014

Pubmed Data : Immunopharmacol Immunotoxicol. 2015 ;37(5):473-80. PMID: 26466646
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Immunomodulatory, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin and NAC decrease alcohol toxicity associated changes in prostaglandin levels.Dec 01, 2000

Pubmed Data : Biochem Pharmacol. 2000 Dec 1;60(11):1665-76. PMID: 11077049
Article Published Date : Dec 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Alcohol Toxicity , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Enzyme Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Curcumin and nicotinamide inhibit radiation-induced nitration in mouse macrophages.Aug 01, 2005

Pubmed Data : Mol Cell Biochem. 2005 Aug;276(1-2):7-13. PMID: 16132679
Article Published Date : Aug 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Nicotinamide
Diseases : Radiation Induced Illness
Pharmacological Actions : Enzyme Inhibitors, Nitric Oxide Inhibitor
[+]

Curcumin inhibits lipopolysaccharide-activated primary microglia.Jan 01, 2009

Pubmed Data : Int Rev Neurobiol. 2009;88:297-334. PMID: 16934299
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Brain: Microglial Activation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Curcumin is a nitric oxide scavenger.Sep 01, 2004

Pubmed Data : Gynecol Oncol. 2004 Sep;94(3):760-8. PMID: 9120760
Article Published Date : Sep 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor
[+]

Curcumin may be a promising agent to alleviate diabetic lung injury and also provides theoretical foundation for the development of diabetes therapy.Jun 25, 2015

Pubmed Data : Clin Exp Pharmacol Physiol. 2015 Jun 26. Epub 2015 Jun 26. PMID: 26111829
Article Published Date : Jun 25, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Diabetes: Oxidative Stress, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Curcumin significantly decreased the LPS-induced pro-inflammatory mediators NO, PGE2, and IL-6 by inhibiting the activation of NF-κB.Jun 30, 2015

Pubmed Data : J Med Food. 2015 Jul ;18(7):786-92. Epub 2014 Dec 9. PMID: 25490740
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin: Lipidated
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages.Jan 17, 1995

Pubmed Data : Biochem Biophys Res Commun. 1995 Jan 17;206(2):533-40. PMID: 7530002
Article Published Date : Jan 17, 1995
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antineoplastic Agents, Nitric Oxide Inhibitor
[+]

Dandelion extract inhibits lipopolysaccharide-induced oxidative stress and nitric oxide production associated with inflammation. Jan 27, 2011

Pubmed Data : J Ethnopharmacol. 2011 Jan 27;133(2):834-42. Epub 2010 Nov 11. PMID: 21075189
Article Published Date : Jan 27, 2011
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Glutathione Deficiency , Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Dandelion leaves have an anti-inflammatory effect on lipopolysaccharide-induced inflammation. Aug 01, 2010

Pubmed Data : J Med Food. 2010 Aug;13(4):870-8. PMID: 20673058
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Diallyl disulfide suppresses the lipopolysaccharide-driven inflammatory response of macrophages by activating the Nrf2 pathway.Dec 31, 2021

Pubmed Data : Food Chem Toxicol. 2022 Jan ;159:112760. Epub 2021 Dec 9. PMID: 34896185
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diarylheptanoids of Curcuma comosa inhibited lipopolysaccharide induced nitric oxide production in macrophage RAW 264.7 cellsDec 31, 2014

Pubmed Data : Nat Prod Commun. 2015 Jan ;10(1):89-93. PMID: 25920227
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Turmeric
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Digested total protein and glutelin from chia seed reduce expression and secretion of markers related to inflammation and atherosclerosis pathways.Sep 30, 2019

Pubmed Data : Mol Nutr Food Res. 2019 Oct ;63(19):e1900021. Epub 2019 Aug 7. PMID: 31343098
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chia
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Discovery of nobiletin from citrus peel as a potent inhibitor of β-amyloid peptide toxicity.Nov 03, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Nov 4 ;11(11). Epub 2019 Nov 4. PMID: 31689949
Article Published Date : Nov 03, 2019
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diterpenoids isolated from the root of Salvia miltiorrhiza and their anti-inflammatory activity.Apr 08, 2019

Pubmed Data : Nat Prod Res. 2019 Apr 9:1-7. Epub 2019 Apr 9. PMID: 30961363
Article Published Date : Apr 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Ellagic acid, gallic acid and punicalagin may be the compounds responsible for the anti-inflammatory potential of P. granatum.Jan 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 14 ;17(1):47. Epub 2017 Jan 14. PMID: 28088220
Article Published Date : Jan 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Gallic Acid, Pomegranate, Punicalagin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Emodin is able to promote the proliferation of chondrocytes.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Dec ;16(6):5384-5389. Epub 2018 Oct 18. PMID: 30542499
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Emodin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Extracts of Maqui and Calafate fruits present important inhibitory like features over the inflammatory response of the interaction between adipocytes and macrophages.Oct 09, 2014

Pubmed Data : J Med Food. 2014 Oct 10. Epub 2014 Oct 10. PMID: 25302660
Article Published Date : Oct 09, 2014
Study Type : In Vitro Study
Additional Links
Substances : Barberry, Maqui
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Folic acid protects motor neurons against the increased homocysteine, inflammation and programmed cell death.Jun 01, 2008

Pubmed Data : Neuropharmacology. 2008 Jun;54(7):1112-9. Epub 2008 Mar 16. PMID: 18436268
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Inflammation
Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoidan has an inhibitory effect on nitric oxide production in lipopolysaccharide-activated primary microglia.Mar 31, 2010

Pubmed Data : Clin Exp Pharmacol Physiol. 2010 Apr ;37(4):422-8. Epub 2009 Oct 16. PMID: 19843098
Article Published Date : Mar 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Brain: Microglial Activation, Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Galangin suppresses renal inflammation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:3018357. Epub 2019 May 26. PMID: 31240210
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Kidney Damage
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Garcinia mangostana Linn. pericarp and alpha-mangostin ameliorate dextran sulfate sodium-induced hepatic injury in mice.May 31, 2021

Pubmed Data : J Physiol Pharmacol. 2021 Jun ;72(3). Epub 2021 Dec 3. PMID: 34873066
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen
Diseases : Diabetic Complications, Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
[+]

Garcinoxanthones B and C significantly inhibited nitric oxide production, which were comparable with the positive control indomethacin.Oct 31, 2016

Pubmed Data : Phytochemistry. 2016 Nov ;131:115-123. Epub 2016 Aug 22. PMID: 27561254
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen, Xanthones
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Lipopolysaccharide-Induced Toxicity, Mangosteen, Natural Substances Versus Drugs, Nitric Oxide Inhibitor, Xanthones
[+]

Ginsenoside Rb1 attenuates activated microglia-induced neuronal damage.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2014 Feb 1 ;9(3):252-9. PMID: 25206809
Article Published Date : Jan 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Brain: Microglial Activation, Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gintonin potently suppresses the nitric oxide and also efficiently suppressed the levels of proinflammatory cytokines.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:624132. Epub 2015 Oct 12. PMID: 26579204
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, MicroRNA modulator, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Glabridin reduces lipopolysaccharide-induced lung injury.Dec 26, 2016

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2016 Dec 27 ;96(48):3893-3897. PMID: 28057160
Article Published Date : Dec 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Isoflavones
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Damage
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Malonaldehyde (MDA) Down-Regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

HDMPPA may exert anti-inflammatory responses by suppressing LPS-induced expression of proinflammatory mediators and cytokines.May 31, 2015

Pubmed Data : J Med Food. 2015 Jun ;18(6):677-84. Epub 2015 Apr 28. PMID: 25919915
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Kimchi
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hesperidin may be a potential agent for the treatment of osteoarthritis.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Oct ;16(4):3721-3727. Epub 2018 Aug 20. PMID: 30233731
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Highly-oxygenated isopimarane-type diterpenes from Orthosiphon stamineus of Indonesia and their nitric oxide inhibitory activity.Feb 28, 2003

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chem Pharm Bull (Tokyo). 2003 Mar ;51(3):268-75. PMID: 12612410
Article Published Date : Feb 28, 2003
Study Type : In Vitro Study
Additional Links
Substances : Orthosiphon
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages.Oct 27, 2014

Pubmed Data : J Ethnopharmacol. 2014 Oct 28 ;156:61-72. Epub 2014 Aug 14. PMID: 25128739
Article Published Date : Oct 27, 2014
Study Type : In Vitro Study
Additional Links
Substances : Phellinus Linteus, Polyphenols
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Hispolon suppresses the LPS-induced activation of inflammatory pathways.Jun 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jun 10 ;12(6). Epub 2020 Jun 10. PMID: 32532087
Article Published Date : Jun 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phellinus Linteus
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Horseradish root extracts had an anti-inflammatory action. Dec 01, 2015

Pubmed Data : Food Funct. 2015 Dec 2 ;6(12):3778-88. PMID: 26411988
Article Published Date : Dec 01, 2015
Study Type : In Vitro Study
Additional Links
Substances : Horseradish
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

I. sanghuang extract might be a valuable medicinal food effective in improving insulin resistance and metabolic syndrome.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:286. Epub 2019 Feb 26. PMID: 30863401
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Medicinal Mushrooms
Diseases : Insulin Resistance, Metabolic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

In this study, we have shown that some polyphenols isolated from A. melanocarpa possess activity of potential health benefits as immunomodulators.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 ;15(7):11626-36. Epub 2014 Jun 30. PMID: 24983479
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Chokeberry, Polyphenols
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Nitric Oxide Inhibitor
Additional Keywords : Proanthocyanidins
[+]

Justicia gendarussa may have potential use in the management of inflammatory conditions such as arthritis.May 31, 2011

Pubmed Data : Pharm Biol. 2011 Jun ;49(6):648-52. PMID: 21554007
Article Published Date : May 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa
Diseases : Arthritis, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-9 (MMP-9) inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Anti-Inflammatory Agents, arthritis, Inflammation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, Plant Extracts
[+]

LED therapy could be a potential non-invasive approach for treatment of retinal damage.Apr 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 May ;89:1320-1330. Epub 2017 Mar 18. PMID: 28320099
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Eye Damage, Retinal Diseases
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Apoptotic, Nitric Oxide Inhibitor
[+]

Loquat leaf inhibits inflammation in macrophages of rats with chronic bronchitis. Jan 01, 2009

Pubmed Data : Am J Chin Med. 2009;37(6):1099-111. PMID: 19938219
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Loquat Leaves
Diseases : Bronchitis: Chronic, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Enzyme Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Loquate leaves suppress lipopolysaccharide-induced adverse, pro-inflammatory changes in mouse macrophages.Jan 01, 2010

Pubmed Data : Am J Chin Med. 2010;38(5):985-94. PMID: 20821828
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Loquat Leaves
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells Mar 22, 2016

Pubmed Data : Free Radic Biol Med. 2016 Mar 23. Epub 2016 Mar 23. PMID: 27016074
Article Published Date : Mar 22, 2016
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation
[+]

M. oleifera extracts suppressed the expression of inflammatory mediators in LPS stimulated macrophages.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 Oct ;11(Suppl 4):S556-63. PMID: 27013794
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

M. oleifera flower extract can be a potent inhibitor of inflammation through NF-κB signaling pathway. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2015 ;2015:720171. Epub 2015 Nov 2. PMID: 26609199
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Mangiferin may act as a potential natural therapeutic candidate for neuroinflammatory diseases.Jan 31, 2021

Pubmed Data : Chin J Nat Med. 2021 Feb ;19(2):112-119. PMID: 33641782
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin
Diseases : Alzheimer's Disease, Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Maple sap and syrup exhibits antioxidant activity, inhibits nitric oxide overproduction and has antiproliferative activity against cancer cells. Feb 04, 2010

Pubmed Data : J Med Food. 2010 Feb 4. Epub 2010 Feb 4. PMID: 20132041
Article Published Date : Feb 04, 2010
Study Type : In Vitro Study
Additional Links
Substances : Maple Syrup
Diseases : Cancers: All, Oxidative Stress
Pharmacological Actions : Antioxidants, Antiproliferative , Nitric Oxide Inhibitor
[+]

Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis.Aug 31, 2012

Pubmed Data : Int Immunopharmacol. 2012 Sep ;14(1):27-31. Epub 2012 Jun 21. PMID: 22705050
Article Published Date : Aug 31, 2012
Study Type : Review
Additional Links
Substances : Peony
Diseases : Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
Additional Keywords : Phytotherapy
[+]

Mechanisms of Paeonia lactiflora in treatment of ulcerative colitis.Oct 08, 2019

Pubmed Data : Med Sci Monit. 2019 Oct 9 ;25:7574-7580. Epub 2019 Oct 9. PMID: 31594914
Article Published Date : Oct 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Peony
Diseases : Ulcerative Colitis
Pharmacological Actions : Nitric Oxide Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis.Feb 07, 2019

Pubmed Data : Biomaterials. 2019 Feb 8 ;200:35-47. Epub 2019 Feb 8. PMID: 30771585
Article Published Date : Feb 07, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Exosomes, Mesenchymal Stem Cells
[+]

Myricetin possesses the therapeutic potential on osteoarthritis.Jul 16, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jul 17 ;75:105742. Epub 2019 Jul 17. PMID: 31325727
Article Published Date : Jul 16, 2019
Study Type : In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Myricitrin modulates NADPH oxidase-dependent ROS production to inhibit endotoxin-mediated inflammation.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:9738745. Epub 2017 Jun 20. PMID: 28751937
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Naringenin exerts anti-inflammatory effects in paraquat-treated SH-SY5Y cells.Feb 05, 2018

Pubmed Data : Neurochem Res. 2018 Feb 6. Epub 2018 Feb 6. PMID: 29411263
Article Published Date : Feb 05, 2018
Study Type : In Vitro Study
Additional Links
Substances : Naringenin
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Naringenin, Pesticide Toxicity
[+]

Neochlorogenic acid might act as a natural anti-inflammatory agent for the treatment of acute pneumonia.Mar 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Mar 18 ;25(6). Epub 2020 Mar 18. PMID: 32197466
Article Published Date : Mar 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Mulberry
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Pneumonia
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective and anti-inflammatory effects of pterostilbene metabolites in human neuroblastoma SH-SY5Y and RAW 264.7 macrophage cells.Jan 17, 2020

Pubmed Data : J Agric Food Chem. 2020 Jan 18. Epub 2020 Jan 18. PMID: 31957426
Article Published Date : Jan 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production.Oct 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2021 Oct 7 ;16(1):98. Epub 2021 Oct 7. PMID: 34620201
Article Published Date : Oct 06, 2021
Study Type : In Vitro Study
Additional Links
Substances : Babchi
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

New tirucallane-type triterpenoids from the resin of Boswellia carteriiand their NO inhibitory activities.Aug 31, 2021

Pubmed Data : Chin J Nat Med. 2021 Sep ;19(9):686-692. PMID: 34561080
Article Published Date : Aug 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Nitric oxide inhibitory constituents as potential anti-neuroinflammatory agents for Alzheimer's disease from Blumea balsamifera.Jan 31, 2018

Pubmed Data : Bioorg Chem. 2018 Feb ;76:449-457. Epub 2017 Dec 5. PMID: 29275263
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sembung Leaf
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
Additional Keywords : Alzheimer's disease, Anti-Inflammatory Agents, Brain Inflammation, Nitric Oxide Inhibitor, Sembung Leaf
[+]

Nobiletin may have potential for the prevention of obesity-related metabolic diseases.Aug 31, 2017

Pubmed Data : J Med Food. 2017 Sep ;20(9):873-881. PMID: 28892456
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 inducer, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Oleanolic acid exerts a neuroprotective effect against microglial cell activation by modulating cytokine release and antioxidant defense systems.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Nov 1 ;9(11). Epub 2019 Nov 1. PMID: 31683841
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oleanolic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin may be a potential agent in the future treatment of osteoarthritis.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Feb ;17(2):3306-3311. Epub 2017 Dec 8. PMID: 29257281
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation
[+]

Physicochemical properties and immunomodulatory activity of the novel continuous phase transition extraction of polysaccharides from Ganoderma lucidum.Oct 18, 2021

Pubmed Data : Food Funct. 2021 Oct 19 ;12(20):9708-9718. Epub 2021 Oct 19. PMID: 34664607
Article Published Date : Oct 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Reishi Mushroom
Pharmacological Actions : Immunomodulatory, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Pine needle could be developed into functional drink to abolish the progression of inflammatory responses in various disease condition.Oct 31, 2019

Pubmed Data : J Food Biochem. 2019 Nov ;43(11):e12994. Epub 2019 Jul 28. PMID: 31659812
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Pine Needle
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pinocembrin, a novel histidine decarboxylase inhibitor with anti-allergic potential in in vitro.Nov 04, 2017

Pubmed Data : Eur J Pharmacol. 2017 Nov 5 ;814:178-186. Epub 2017 Aug 15. PMID: 28821452
Article Published Date : Nov 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Allergies, Klebsiella Infections
Pharmacological Actions : Anti-Allergic Agents, Cyclooxygenase 2 Inhibitors, Enzyme Inhibitors, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Piperine and phenylamide acted synergistically on the leishmania amazonensis parasites.Nov 30, 2011

Pubmed Data : Phytochemistry. 2011 Dec ;72(17):2155-64. Epub 2011 Aug 30. PMID: 21885074
Article Published Date : Nov 30, 2011
Study Type : In Vitro Study
Additional Links
Substances : Piperidines, Piperine
Diseases : Leishmaniasis, Triglycerides: Elevated
Pharmacological Actions : Leishmanicidal, Nitric Oxide Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Polyacetylenes might greatly contribute to the anti-inflammatory activity of the rhizomes of A. macrocephala.Feb 02, 2014

Pubmed Data : J Ethnopharmacol. 2014 Feb 3 ;151(2):791-9. Epub 2013 Dec 1. PMID: 24296088
Article Published Date : Feb 02, 2014
Study Type : In Vitro Study
Additional Links
Substances : Bai Zhu
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Polysaccharides from M. conica play a potential role on immunomodulation and treating related diseases.Apr 30, 2012

Pubmed Data : Appl Microbiol Biotechnol. 2012 May ;94(3):763-71. Epub 2011 Dec 11. PMID: 22159604
Article Published Date : Apr 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Mushrooms: All
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Immunomodulatory, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Polysaccharides
[+]

Potential roles of dietary flavonoids from Citrus aurantium L. var. amara Engl. in atherosclerosis development.Dec 17, 2019

Pubmed Data : Food Funct. 2019 Dec 18. Epub 2019 Dec 18. PMID: 31850465
Article Published Date : Dec 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Bitter Orange
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Propolis reduces the expression of autophagy-related proteins in chondrocytes under interleukin-1β stimulus.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Aug 1 ;20(15). Epub 2019 Aug 1. PMID: 31374866
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Nitric Oxide Inhibitor
[+]

Protective effect of gedunin on TLR-mediated inflammation by modulation of inflammasome activation and cytokine production.Dec 31, 2016

Pubmed Data : Pharmacol Res. 2017 01 ;115:65-77. Epub 2016 Sep 15. PMID: 27641928
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Neem
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of silibinin on LPS-induced inflammation in human periodontal ligament cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Chem. 2022 ;10:1019663. Epub 2022 Oct 10. PMID: 36300030
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Lipopolysaccharide-Induced Toxicity, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , Interleukin-6 Downregulation, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pterostilbene exhibits anti-inflammatory properties.Aug 27, 2008

Pubmed Data : J Agric Food Chem. 2008 Aug 27;56(16):7502-9. Epub 2008 Jul 26. PMID: 18656926
Article Published Date : Aug 27, 2008
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Stilbenes
[+]

Pumpkin polysaccharides: Purification, characterization and hypoglycemic potential.Aug 06, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 7 ;139:842-849. Epub 2019 Aug 7. PMID: 31400422
Article Published Date : Aug 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Punicalagin played an important role in the attenuation of LPS-induced inflammatory responses in RAW264.7 macrophages.Nov 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Nov 15 ;11(11). Epub 2019 Nov 15. PMID: 31731808
Article Published Date : Nov 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Punicalagin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Purple-fleshed sweet potato extracts could induce apoptosis in MCF-7 and SNU-1 cancer cells through extrinsic and intrinsic pathway.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:768093. Epub 2015 Oct 5. PMID: 26509161
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Sweet Potato: Purple
Diseases : Breast Cancer, Colon Cancer, Gastric Cancer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

Pycnogenol has potential as a therapeutic agent for the treatment of allergic asthma.Nov 30, 2013

Pubmed Data : Food Chem Toxicol. 2013 Dec ;62:681-6. Epub 2013 Oct 9. PMID: 24120901
Article Published Date : Nov 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Asthma, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Red orange extract exerts anti-inflammatory effects probably through the suppression of COX-2 and iNOS expression.Sep 01, 2010

Pubmed Data : Nat Prod Res. 2010 Sep;24(15):1469-80. PMID: 20812134
Article Published Date : Sep 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Orange
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Resveratrol and tannic acid may exert a chemopreventive action by inhibiting nitric oxide in cancer cells. Oct 01, 2010

Pubmed Data : Cancer Biother Radiopharm. 2010 Oct;25(5):577-80. Epub 2010 Sep 28. PMID: 20874429
Article Published Date : Oct 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Tannic Acid
Diseases : Breast Cancer, Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Nitric Oxide Inhibitor
Additional Keywords : Stilbenes
[+]

Resveratrol inhibits high glucose-induced cellular aging in endothelial cells. May 01, 2010

Pubmed Data : Clin Exp Pharmacol Physiol. 2010 May;37(5-6):630-5. Epub 2010 Feb 4. PMID: 20132235
Article Published Date : May 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Aging, Endothelial Dysfunction, Hyperglycemia
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor, SIRT1 Activator
Additional Keywords : Stilbenes
[+]

Resveratrol suppresses nitric oxide synthase and down-regulates the activation of NFkappaB in macrophages.Feb 01, 1999

Pubmed Data : Br J Pharmacol. 1999 Feb;126(3):673-80. PMID: 10188978
Article Published Date : Feb 01, 1999
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Resveratrol, Stilbenes
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Enzyme Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Rosmarinic acid attenuates the lipopolysaccharide-provoked inflammatory response of vascular smooth muscle cell.Mar 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Mar 31 ;15(4). Epub 2022 Mar 31. PMID: 35455434
Article Published Date : Mar 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rosemaric Acid
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sesamol ameliorated inflammatory and oxidative damage.Jul 31, 2015

Pubmed Data : Inflamm Res. 2015 Aug ;64(8):577-88. Epub 2015 Jun 10. PMID: 26059394
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Sesamol
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Nrf2 activation, Prostaglandin PGE2 downregulation
[+]

Structural characterization of blackberry wine polysaccharides and immunomodulatory effects on LPS-activated RAW 264.7 macrophages.Aug 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2018 Aug 15 ;257:143-149. Epub 2018 Feb 24. PMID: 29622190
Article Published Date : Aug 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Blackberry
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Structural characterization of withanolide glycosides from the roots of Withania somnifera and their potential biological activities.Mar 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2022 Mar 13 ;11(6). Epub 2022 Mar 13. PMID: 35336649
Article Published Date : Mar 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Helicobacter Pylori Infection, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Antioxidants, Nitric Oxide Inhibitor
[+]

Taraxasterol may be a useful agent for prevention and treatment of osteoarthritis.Jun 04, 2015

Pubmed Data : Eur J Pharmacol. 2015 Jun 5 ;756:38-42. Epub 2015 Mar 20. PMID: 25797286
Article Published Date : Jun 04, 2015
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Tart cherries may be effective in reducing inflammatory and oxidative stress mediated signals.Sep 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2016 Sep 22 ;5(4). Epub 2016 Sep 22. PMID: 27669317
Article Published Date : Sep 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tart Cherry
Diseases : Cognitive Decline/Dysfunction, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tea, rosemary and turmeric inhibit inflammation.Sep 04, 1995

Pubmed Data : Cancer Lett. 1995 Sep 4;96(1):23-9. PMID: 7553604
Article Published Date : Sep 04, 1995
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Curcumin, Rosemary, Tea
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.Jan 10, 2020

Pubmed Data : Food Res Int. 2020 11 ;137:109647. Epub 2020 Sep 1. PMID: 33233226
Article Published Date : Jan 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Sweet Potato: Purple
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The antioxidant and anti-inflammatory effects of flavonoids from propolis via Nrf2 and NF-κB pathways.Aug 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Aug 13 ;11(16). Epub 2022 Aug 13. PMID: 36010439
Article Published Date : Aug 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis, Flavonoids
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

The application of pulsed electric field resulted in a higher total carotenoid content in the purée than its untreated counterpart.Mar 31, 2016

Pubmed Data : Food Chem. 2016 Apr 1 ;196:654-64. Epub 2015 Oct 8. PMID: 26593539
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carrot
Diseases : Oxidative Stress
Pharmacological Actions : Gastroprotective, Nitric Oxide Inhibitor
[+]

The immunomodulatory effects of active ingredients from Nigella sativa in RAW264.7 cells through NF-κB/MAPK signaling pathways.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:899797. Epub 2022 May 31. PMID: 35711536
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The mechanism of honey in reversing metabolic syndrome.Feb 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Feb 4 ;26(4). Epub 2021 Feb 4. PMID: 33557218
Article Published Date : Feb 03, 2021
Study Type : Review
Additional Links
Substances : Honey
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nitric Oxide Inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2022 Sep ;50(3). Epub 2022 Jul 29. PMID: 35904170
Article Published Date : Aug 31, 2022
Study Type : Review
Additional Links
Substances : Xanthones
Diseases : Cardiovascular Diseases, Metabolic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

The results of this research suggest that natural extracts of E. cardamomum and C. longa possess anti-inflammatory effects.Sep 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Sep 14 ;10(9). Epub 2021 Sep 14. PMID: 34579443
Article Published Date : Sep 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cardamom, Turmeric
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

These findings identify Origanum majorana as a promising chemopreventive and therapeutic candidate that modulate breast cancer growth and metastasis.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(7):e68808. Epub 2013 Jul 10. PMID: 23874773
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Marjoram
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

These findings showed that fisetin improves Meglumine antimoniate side effects as well as prevent the growth of promastigotes.May 31, 2017

Pubmed Data : Pathog Glob Health. 2017 Jun ;111(4):176-185. Epub 2017 Apr 7. PMID: 28385129
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Leishmaniasis
Pharmacological Actions : Leishmanicidal, Nitric Oxide Inhibitor
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These results demonstrate the immunomodulatory effects of L. barbarium polysaccharides and its effective uptake by macrophages and intestine.Mar 15, 2020

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Pubmed Data : Molecules. 2020 Mar 16 ;25(6). Epub 2020 Mar 16. PMID: 32188121
Article Published Date : Mar 15, 2020
Study Type : In Vitro Study
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Substances : Goji
Pharmacological Actions : Immunomodulatory, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor