Osteoprotective

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218 Substances Researched for Osteoprotective
NameACCKFocus
Puerarin1343Locked
Vitamin C1137Locked
Frankincense535Locked
Isoflavones332Locked
Citrus naringin526Locked
Resveratrol323Locked
Plum321Locked
Red Clover321Locked
Fruit: All120Locked
Vegetables: All 120Locked
Vitamin K2: Menaquinone-7220Locked
Vitamin D515Locked
Cryptoxanthin313Locked
Flavonoids813Locked
Reishi Mushroom313Locked
Royal Jelly313Locked
Vitamin K2313Locked
Blueberry312Locked
Flaxseed212Locked
Magnesium212Locked
Oyster Mushroom212Locked
Whey212Locked
Berberine610Locked
Bromelain110Locked
Brown Rice110Locked
Carotenoids110Locked
Diosgenin510Locked
Fermented Foods and Beverages110Locked
Japanese mugwort110Locked
Lactobacillus reuteri110Locked
Milk110Locked
Paprika110Locked
Pine Bark Extract110Locked
Probiotics110Locked
Vitamin B-5 (Pantothenic Acid)110Locked
Vitamin K2: (MK-4)110Locked
Yoghurt110Locked
Zinc610Locked
Ginsenosides58Locked
Paeoniflorin48Locked
Quercetin38Locked
Boron47Locked
Carnosic Acid27Locked
Myricetin47Locked
NAC (N-acetyl-L-cysteine)47Locked
Tanshinone IIA47Locked
Emodin36Locked
Hesperidin36Locked
Kaempferol36Locked
Pueraria mirifica36Locked
Astaxanthin35Locked
Coenzyme Q1035Locked
Curcumin45Locked
Psychedelics:All 35Locked
Ursolic Acid35Locked
Allicin24Locked
Arctigenin24Locked
Asiatic Acid24Locked
Babchi24Locked
Black Tea24Locked
Formononetin24Locked
Fucoidan34Locked
Gastrodin24Locked
Grape Seed Extract24Locked
Green Tea34Locked
Guava24Locked
Hops24Locked
Kudzu24Locked
Lactobacillus plantarum24Locked
Lotus 44Locked
Lycopene34Locked
Melatonin34Locked
Oleanolic acid24Locked
Olive Oil24Locked
Polyphenols34Locked
Salvia miltiorrhiza24Locked
Spinach24Locked
Tart Cherry24Locked
Theaflavins24Locked
Artesunate23Locked
EGCG (Epigallocatechin gallate)23Locked
Genipin23Locked
Genistein23Locked
Guduchi 23Locked
Isoquercitrin23Locked
Xanthohumol23Locked
18β-Glycyrrhetinic Acid12Locked
Adlay12Locked
Aloe Vera12Locked
Alpha-Lipoic Acid12Locked
Antrodia camphorata12Locked
Apple12Locked
Astragaloside12Locked
Bergamot orange12Locked
Beta-Caryophyllene12Locked
Bifidobacterium Longum 12Locked
Black Currant12Locked
Brown Rice: Pre-Germinated12Locked
Cannabidiol12Locked
Cannabinoids 22Locked
Cannabinoids: Synthetic12Locked
Chia12Locked
Chlorogenic Acid12Locked
Chokeberry12Locked
Chrysanthemum Indicum22Locked
Cordyceps Militaris12Locked
Crocin12Locked
DHA (Docosahexaenoic Acid)12Locked
Deguelin12Locked
Diosmetin12Locked
Eriodictyol12Locked
Fenugreek12Locked
Fisetin12Locked
Galacto-oligosaccharides12Locked
Garcinia Mangostana12Locked
Garden Cress (Lepidium sativum) 12Locked
Garlic12Locked
Ginger22Locked
Grape12Locked
Grapefruit12Locked
Homeopathic Medicine: All12Locked
Honeydew (melon)12Locked
Horsetail12Locked
Hydrogen Water12Locked
Isoliquiritigenin12Locked
Kefir12Locked
Kimchi12Locked
Krill12Locked
Lactobacillus casei12Locked
Lactobacillus rhamnosus GG12Locked
Ligustrazine22Locked
Liquiritigenin12Locked
Luteolin12Locked
Maitake Mushroom12Locked
Mangiferin12Locked
Marigold12Locked
Mugwort12Locked
Mushrooms: All 12Locked
Nettle12Locked
Nigella sativa (aka Black Seed)12Locked
Nobiletin 12Locked
Noni12Locked
Nordihydroguaiaretic acid (NDGA)12Locked
Olive leaf extract12Locked
Oridonin12Locked
Paeonol12Locked
Palash12Locked
Panax Notoginseng12Locked
Parthenolide12Locked
Passion Flower12Locked
Persimmon 12Locked
Phellinus Linteus12Locked
Phloretin12Locked
Pomegranate12Locked
Pomegranate Seed12Locked
Porridge12Locked
Prebiotics12Locked
Prickly Pear Cactus12Locked
Punicalagin22Locked
Rice Bran12Locked
Rooibos12Locked
Rosemary12Locked
Safflower12Locked
Seaweed: Brown 22Locked
Sesamin12Locked
Shiitake Mushroom 12Locked
Shikonin12Locked
Terminalia chebula12Locked
Thyme12Locked
Tomatidine 22Locked
White Mulberry 12Locked
White Tea12Locked
acetyl-11-keto-beta-boswellic acid12Locked
2,3,5,4'-tetrahydroxystilbene-2-O-β -D-glucoside (THSG)11Locked
Angelica11Locked
Anthocyanins11Locked
B-complex11Locked
Bai Zhu11Locked
Beer11Locked
Bergamot11Locked
Broccoli11Locked
Burdock11Locked
Cafestol11Locked
Catechin 11Locked
Chocolate11Locked
Chondroitin Sulfate11Locked
Cocoa11Locked
DHEA (Dehydroepiandrosterone)11Locked
Daisy11Locked
Delphinidin11Locked
Fish Oil11Locked
Ginseng (Korean)11Locked
Glucosamine11Locked
Glycyrrhizin11Locked
Honeybush11Locked
Kahweol11Locked
Licorice11Locked
Loquat11Locked
Magnolol11Locked
Maqui 11Locked
Moxibustion11Locked
Orange: Mandarin11Locked
Peony11Locked
Piceatannol 11Locked
Polyunsaturated Fatty Acids (PUFAs)11Locked
Prune11Locked
Prunella vulgaris11Locked
Purslane11Locked
Rose 11Locked
Rosemaric Acid11Locked
Selenium11Locked
Spirulina11Locked
Sulforaphane11Locked
Thymol11Locked
Vitamin A11Locked
Vitamin E11Locked
Vitamin K11Locked
Water: Deep Sea11Locked

View the Evidence:
587 Abstracts with Osteoprotective Research

[+]

Effectiveness of Acupuncture for relieving chemotherapy-induced bone marrow suppression.May 09, 2023

Pubmed Data : J Integr Complement Med. 2023 May 10. Epub 2023 May 10. PMID: 37163212
Article Published Date : May 09, 2023
Study Type : Meta Analysis, Review
Additional Links
Diseases : Chemotherapy
Therapeutic Actions : Acupuncture
Pharmacological Actions : Chemoprotective Agents, Osteoprotective
[+]

Nigella sativa and health outcomes: An overview of systematic reviews and meta-analyses.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2023 ;10:1107750. Epub 2023 Mar 28. PMID: 37057067
Article Published Date : Dec 31, 2022
Study Type : Meta Analysis, Review
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetes Mellitus: Type 2, Hypercholesterolemia, Hypertension, Nonalcoholic fatty liver disease (NAFLD), Obesity, Osteoporosis
Pharmacological Actions : Antihypertensive Agents, Hypolipidemic, Osteoprotective
[+]

The present study demonstrated that n-3 PUFA supplementation might not have a significant effect on bone mineral density or bone metabolism markers.Jun 18, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jun 19 ;15(12). Epub 2023 Jun 19. PMID: 37375709
Article Published Date : Jun 18, 2023
Study Type : Meta Analysis, Review
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Therapeutic potential of senolytic agent quercetin in osteoarthritis.Jul 10, 2023

Pubmed Data : Ageing Res Rev. 2023 Jul 11 ;90:101989. Epub 2023 Jul 11. PMID: 37442369
Article Published Date : Jul 10, 2023
Study Type : Meta Analysis, Review
Additional Links
Substances : Quercetin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Boswellia and its extract may be an effective and safe treatment option for patient with osteoarthritis.Jul 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Jul 17 ;20(1):225. Epub 2020 Jul 17. PMID: 32680575
Article Published Date : Jul 16, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Combined exercise interventions appear to be effective in preserving postmenopausal women's BMD at lumbar spine, femoral neck, hip and total body.Mar 02, 2017

Pubmed Data : J Orthop Sports Phys Ther. 2017 Mar 3:1-28. Epub 2017 Mar 3. PMID: 28257620
Article Published Date : Mar 02, 2017
Study Type : Meta Analysis
Additional Links
Diseases : Osteoarthritis, Postmenopausal Complications
Therapeutic Actions : Exercise
Pharmacological Actions : Osteoprotective
[+]

Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2022 ;10:979649. Epub 2022 Aug 11. PMID: 36033779
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Naringin had been shown to promote bone formation in OVX rats. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6016874. Epub 2021 Feb 10. PMID: 33628301
Article Published Date : Dec 31, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Puerarin showed upregulating effects on bone mass in ovariectomy-induced postmenopausal osteoporosis.Jul 02, 2019

Pubmed Data : Curr Stem Cell Res Ther. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31269886
Article Published Date : Jul 02, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Soy isoflavones prevent bone resorption and loss.Jul 09, 2019

Pubmed Data : Crit Rev Food Sci Nutr. 2019 Jul 10:1-15. Epub 2019 Jul 10. PMID: 31290343
Article Published Date : Jul 09, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Isoflavones
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

The efficacy and safety of Curcuma longa Extract and curcumin supplements on osteoarthritis.May 20, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2021 May 21. Epub 2021 May 21. PMID: 34017975
Article Published Date : May 20, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Turmeric
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

The efficacy and safety of ipriflavone in postmenopausal women with osteopenia or osteoporosis.Dec 31, 2019

Pubmed Data : Pharmacol Res. 2020 09 ;159:104860. Epub 2020 May 12. PMID: 32407952
Article Published Date : Dec 31, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Ipriflavone
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

The findings of this study indicate that resveratrol supplementation increased some key bone biomarkers.Sep 05, 2019

Pubmed Data : Ann N Y Acad Sci. 2019 Sep 6. Epub 2019 Sep 6. PMID: 31490554
Article Published Date : Sep 05, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Resveratrol
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

There was an association between the increase of at least one serving of fruits and vegetables per day and decreases in the risk of fractures.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(5):e0217223. Epub 2019 May 31. PMID: 31150426
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Fractures: Bone, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

This present systematic review indicated that acupuncture could be an effective therapy for treating osteoporosis.Dec 31, 2017

Pubmed Data : Am J Chin Med. 2018 ;46(3):489-513. Epub 2018 Apr 4. PMID: 29614884
Article Published Date : Dec 31, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Acupuncture
Pharmacological Actions : Osteoprotective
[+]

3 weekly sessions of whole body vibration or Pilates administered for 6 months provided an equal effect on bone mass density.Feb 11, 2018

Pubmed Data : J Geriatr Phys Ther. 2018 Feb 12. Epub 2018 Feb 12. PMID: 29443867
Article Published Date : Feb 11, 2018
Study Type : Human Study
Additional Links
Diseases : Postmenopausal Disorders
Therapeutic Actions : Pilates, Whole-Body Vibration
Pharmacological Actions : Osteoprotective
[+]

Artemisia princeps as a promising therapeutic option for the improvement of postmenopausal osteoporosis.Dec 31, 2015

Pubmed Data : J Nutr Health Aging. 2016 ;20(5):533-9. PMID: 27102792
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Japanese mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.Oct 31, 2019

Pubmed Data : J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : Bromelain, Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Blackcurrants reduce the risk of postmenopausal osteoporosis.Nov 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 23 ;14(23). Epub 2022 Nov 23. PMID: 36501004
Article Published Date : Nov 22, 2022
Study Type : Human Study
Additional Links
Substances : Black Currant
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Risk Reduction
[+]

Blueberries may have a positive effect on joint health by reducing pain, stiffness, and difficulty to perform daily activities.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID: 31224734
Article Published Date : May 31, 2019
Study Type : Human Study
Additional Links
Substances : Blueberry
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2017 Sep ;106(3):909-920. Epub 2017 Aug 2. PMID: 28768651
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Isoflavones, Probiotics, Red Clover
Diseases : Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Daily consumption of 100 g dried plum for 12 months has modest bone-protective effects in men.Dec 31, 2021

Pubmed Data : J Med Food. 2022 Jan ;25(1):40-47. Epub 2021 Oct 29. PMID: 34714130
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Prune
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Diet-derived circulating antioxidants and risk of knee osteoarthritis, hip osteoarthritis and rheumatoid arthritis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Med (Lausanne). 2023 ;10:1147365. Epub 2023 Jun 21. PMID: 37415773
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Substances : Vitamin A
Diseases : Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
[+]

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183
Article Published Date : Oct 29, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Bone Fractures, Osteoporosis, Sarcopenia
Pharmacological Actions : Osteoprotective
[+]

Dried plum in its whole form is a promising and efficacious functional food therapy for preventing bone loss in postmenopausal women.May 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 May 14 ;9(5). Epub 2017 May 14. PMID: 28505102
Article Published Date : May 13, 2017
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Dried plum ingestion increases the osteoblastogenic capacity of human serum.Jun 30, 2017

Pubmed Data : J Med Food. 2017 Jul ;20(7):653-658. Epub 2017 Apr 26. PMID: 28445075
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoarthrosis
Pharmacological Actions : Osteoprotective
[+]

Effect of Curcuma longa extract on serum inflammatory markers and MRI-based synovitis in knee osteoarthritis.Dec 17, 2022

Pubmed Data : Phytomedicine. 2022 Dec 18 ;109:154616. Epub 2022 Dec 18. PMID: 36610110
Article Published Date : Dec 17, 2022
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Effect of fermented soymilk-honey from different probiotics on osteocalcin level in menopausal women.Oct 12, 2021

Pubmed Data : Nutrients. 2021 Oct 13 ;13(10). Epub 2021 Oct 13. PMID: 34684581
Article Published Date : Oct 12, 2021
Study Type : Human Study
Additional Links
Substances : Honey, Lactobacillus casei, Lactobacillus plantarum, Soy: Fermented
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Effect of ginseng extracts on the improvement of osteopathic and arthritis symptoms in women with osteopenia.Sep 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Sep 24 ;13(10). Epub 2021 Sep 24. PMID: 34684351
Article Published Date : Sep 23, 2021
Study Type : Human Study
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Effects of genistein aglycone in glucocorticoid induced osteoporosis.Jun 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2023 Jul ;163:114821. Epub 2023 May 9. PMID: 37167726
Article Published Date : Jun 30, 2023
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Effects of high intensity dynamic resistance exercise and whey protein supplements on osteosarcopenia.Aug 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Aug 5 ;12(8). Epub 2020 Aug 5. PMID: 32764397
Article Published Date : Aug 04, 2020
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : Bone Diseases
Therapeutic Actions : Exercise: Resistance Training
Pharmacological Actions : Osteoprotective
[+]

Effects of ipriflavone on postmenopausal syndrome and osteoporosis. Jan 31, 2010

Pubmed Data : Gynecol Endocrinol. 2010 Feb ;26(2):76-80. PMID: 19672742
Article Published Date : Jan 31, 2010
Study Type : Human Study
Additional Links
Substances : Ipriflavone
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
[+]

Effects of short-term dried prune intake on markers of bone resorption and vascular function in healthy postmenopausal women.Sep 30, 2019

Pubmed Data : J Med Food. 2019 Oct ;22(10):982-992. Epub 2019 Jun 13. PMID: 31194598
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : Prune
Diseases : Cardiovascular Diseases, Osteoporosis, Postmenopausal Complications
Pharmacological Actions : Osteoprotective
[+]

Efficacy and safety of a krill oil, astaxanthin, and oral hyaluronic acid complex on joint health in people with mild osteoarthritis.Aug 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Aug 29 ;15(17). Epub 2023 Aug 29. PMID: 37686801
Article Published Date : Aug 28, 2023
Study Type : Human Study
Additional Links
Substances : Astaxanthin, Krill
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Electroacupuncture on motor function in patients with primary osteoporosis: a randomized controlled trial.Feb 11, 2022

Pubmed Data : Zhongguo Zhen Jiu. 2022 Feb 12 ;42(2):145-9. PMID: 35152577
Article Published Date : Feb 11, 2022
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Osteoprotective
[+]

Fermentation of Pleurotus ostreatus and Ganoderma lucidum mushrooms and their extracts by the gut microbiota of healthy and osteopenic women.Jan 31, 2021

Pubmed Data : Food Funct. 2021 Feb 1. Epub 2021 Feb 1. PMID: 33521800
Article Published Date : Jan 31, 2021
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Fermented Foods and Beverages, Oyster Mushroom, Reishi Mushroom
Diseases : Osteopenia
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

French maritime pine bark extract supplements can be used as a preventive strategy for bone loss in postmenopausal osteopenic women.Mar 23, 2019

Pubmed Data : Phytother Res. 2019 Mar 24. Epub 2019 Mar 24. PMID: 30907034
Article Published Date : Mar 23, 2019
Study Type : Human Study
Additional Links
Substances : Pine Bark Extract
Diseases : Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
[+]

Functional outcomes of Tai Chi exercise prescription in women with knee osteoarthritis.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sports Med Health Sci. 2022 Dec ;4(4):239-244. Epub 2022 Nov 12. PMID: 36600975
Article Published Date : Nov 30, 2022
Study Type : Human Study
Additional Links
Diseases : Osteoarthritis
Therapeutic Actions : Tai Chi
Pharmacological Actions : Osteoprotective
[+]

Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults.Apr 30, 2017

Pubmed Data : Osteoporos Int. 2017 May 1. Epub 2017 May 1. PMID: 28462469
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Substances : Yoghurt
Diseases : Aging, Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Aging, Bone Diseases, Osteoprotective, Yoghurt
[+]

Hemp seed oil in association with β-caryophyllene, myrcene and ginger extract as a nutraceutical integration in knee osteoarthritis.Jan 17, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2023 Jan 18 ;59(2). Epub 2023 Jan 18. PMID: 36837393
Article Published Date : Jan 17, 2023
Study Type : Human Study
Additional Links
Substances : Beta-Caryophyllene, Ginger, Hemp Seed
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

Hyperoside alleviates postmenopausal osteoporosis.Jun 30, 2023

Pubmed Data : Am J Reprod Immunol. 2023 Jul ;90(1):e13709. Epub 2023 May 8. PMID: 37157916
Article Published Date : Jun 30, 2023
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Icariin promoted the proliferation and osteogenic differentiation of impaired BMSCs by upregulating GLI-1. Jul 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Orthop Surg Res. 2023 Jul 15 ;18(1):500. Epub 2023 Jul 15. PMID: 37454090
Article Published Date : Jul 14, 2023
Study Type : Human Study
Additional Links
Substances : Icariin
Diseases : Diabetes Mellitus: Type 2, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density.Jun 20, 2018

Pubmed Data : J Intern Med. 2018 Jun 21. Epub 2018 Jun 21. PMID: 29926979
Article Published Date : Jun 20, 2018
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Long-term ultra-high hydrostatic pressurized brown rice intake prevents bone mineral density decline in elderly Japanese individuals.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2019 ;65(Supplement):S88-S92. PMID: 31619654
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Brown Rice
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis.Dec 31, 2019

Pubmed Data : Int J Vitam Nutr Res. 2020 Jan ;90(1-2):42-48. Epub 2019 Feb 28. PMID: 30816822
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin K2: (MK-4)
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

MK-7 in addition to ordinary meals could improve osteocalcin γ-carboxylation status.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61(6):471-80. PMID: 26875489
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Moderate consumption of blueberries may be an effective strategy to attenuate bone loss in healthy postmenopausal women.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2023 Aug ;118(2):382-390. Epub 2023 Jun 1. PMID: 37269909
Article Published Date : Jul 31, 2023
Study Type : Human Study
Additional Links
Substances : Blueberry
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Paprika carotenoid extract supplementation suppresses bone resorption and contributes to maintaining bone quality in postmenopausal women.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2020 ;64. Epub 2020 Oct 6. PMID: 33240029
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Carotenoids, Paprika
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults.Jan 12, 2023

Pubmed Data : Phytother Res. 2023 Jan 13. Epub 2023 Jan 13. PMID: 36637040
Article Published Date : Jan 12, 2023
Study Type : Human Study
Additional Links
Substances : Perilla
Diseases : Aging, Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Prunes preserve hip bone mineral density in a 12-month randomized controlled trial.Oct 05, 2022

Pubmed Data : Am J Clin Nutr. 2022 Oct 6 ;116(4):897-910. PMID: 35798020
Article Published Date : Oct 05, 2022
Study Type : Human Study
Additional Links
Diseases : Hip Fracture, Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Red clover extract had positive effect on bone health in healthy menopausal women.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:689138. Epub 2015 Jul 21. PMID: 26265926
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Red Clover
Diseases : Menopausal Syndrome
Pharmacological Actions : Osteoprotective
[+]

Regular consumption of lactose-free milk and performing whole-body vibration exercises can delay the progression of bone density loss in older adults.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Phys Ther Sci. 2017 Jul ;29(7):1125-1128. Epub 2017 Jul 15. PMID: 28744030
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Milk
Diseases : Aging
Therapeutic Actions : Whole-Body Vibration
Pharmacological Actions : Osteoprotective
[+]

Regular supplementation with resveratrol improves bone mineral density in postmenopausal women.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Bone Miner Res. 2020 Nov ;35(11):2121-2131. Epub 2020 Jul 14. PMID: 32564438
Article Published Date : Oct 31, 2020
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Resveratrol-induced suppression of C-type natriuretic peptide associates with increased vertebral bone density.Apr 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JBMR Plus. 2023 May ;7(5):e10732. Epub 2023 Mar 1. PMID: 37197320
Article Published Date : Apr 30, 2023
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Royal jelly consumption may ameliorate decreases in femoral bone mineral density and strength in postmenopausal women.Sep 02, 2020

Pubmed Data : Climacteric. 2020 Sep 3:1-7. Epub 2020 Sep 3. PMID: 32880201
Article Published Date : Sep 02, 2020
Study Type : Human Study
Additional Links
Substances : Royal Jelly
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Sufficient plasma vitamin C is related to greater bone mineral density among postmenopausal women.Sep 10, 2021

Pubmed Data : J Nutr. 2021 Sep 11. Epub 2021 Sep 11. PMID: 34510185
Article Published Date : Sep 10, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Supplementation with vitamin D over four years was associated with significantly less progression of knee joint abnormalities.Jul 07, 2019

Pubmed Data : Arthritis Care Res (Hoboken). 2019 Jul 8. Epub 2019 Jul 8. PMID: 31282125
Article Published Date : Jul 07, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin C, Vitamin D
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Tamarindus indica seed extract-based botanical compositions alleviate knee pain and improve joint function in mild-to-moderate osteoarthritis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2226139. Epub 2022 Jan 19. PMID: 35096104
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Tamarind
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

The combination of β-cryptoxanthin and vitamin C is inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(3):185-91. PMID: 27465725
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Cryptoxanthin, Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Factors
[+]

These result shows that pantothenic acid rich diet can protect bone loss from estrogen deficiency.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(8):5008-5018. Epub 2019 Aug 15. PMID: 31497217
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-5 (Pantothenic Acid)
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

This study indicates that daily consumption of 6 g/d of flaxseed oil may reduce bone resorption in hemodialysis patients.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Kidney Dis. 2018 07 ;12(4):215-222. PMID: 30087216
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Bone Diseases, Hemodialysis
Pharmacological Actions : Osteoprotective
[+]

Vitamin E (mixed-tocopherol) supplementation in postmenopausal osteopenic women may have a preventive effect on bone loss through anti-resorptive activity.Nov 24, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Nov 25 ;13(12). Epub 2021 Nov 25. PMID: 34959779
Article Published Date : Nov 24, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Vitamin K2 supplementation in dose of 90 µg/day performed a significant effect on reducing bone loss in postmenopausal women.Feb 13, 2020

Pubmed Data : Calcif Tissue Int. 2020 Feb 14. Epub 2020 Feb 14. PMID: 32060566
Article Published Date : Feb 13, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Vitamin MK-7 preserves trabecular bone structure at the tibia.Nov 30, 2016

Pubmed Data : Eur J Endocrinol. 2016 Dec ;175(6):541-549. Epub 2016 Sep 13. PMID: 27625301
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Yoga appears to raise bone mineral density in the spine and the femur safely.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Top Geriatr Rehabil. 2016 Apr ;32(2):81-87. Epub 2015 Nov 5. PMID: 27226695
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Yoga
Pharmacological Actions : Osteogenic, Osteoprotective
[+]

Ascorbic acid could be a promising candidate for the prevention and healing of bone-related diseases.Dec 03, 2019

Pubmed Data : J Biol Regul Homeost Agents. 2019 Dec 4 ;33(6). Epub 2019 Dec 4. PMID: 31797649
Article Published Date : Dec 03, 2019
Study Type : Human In Vitro
Additional Links
Substances : Vitamin C
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Carnosic acid attenuates cartilage degeneration in human articular chondrocytes.Jul 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Jul 5 ;830:1-8. Epub 2018 Apr 17. PMID: 29678719
Article Published Date : Jul 04, 2018
Study Type : Human In Vitro
Additional Links
Substances : Carnosic Acid
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Osteoprotective
[+]

Quercetin stimulates bone marrow mesenchymal stem cell differentiation through an estrogen receptor-mediated pathway.Jan 01, 2018

Pubmed Data : Biomed Res Int. 2018 ;2018:4178021. Epub 2018 Mar 15. PMID: 29736392
Article Published Date : Jan 01, 2018
Study Type : Human In Vitro
Additional Links
Substances : Quercetin
Pharmacological Actions : Estrogen Receptor Modulators, Osteogenic, Osteoprotective , Regenerative
Additional Keywords : Bone Regeneration
[+]

Acacetin prevents bone loss by disrupting osteoclast formation and promoting type H vessel formation in ovariectomy-induced osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2022 ;10:796227. Epub 2022 Apr 19. PMID: 35517504
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Cryptotanshinone suppressed postmenopausal osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2821984. Epub 2022 Jan 29. PMID: 35132325
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Formononetin improves the inflammatory response and bone destruction in knee joint lesions.Mar 31, 2023

Pubmed Data : Phytother Res. 2023 Apr 1. Epub 2023 Apr 1. PMID: 37002905
Article Published Date : Mar 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Formononetin
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Osteoprotective
[+]

Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes.Dec 04, 2022

Pubmed Data : Eur J Pharmacol. 2022 Dec 5 ;936:175347. Epub 2022 Oct 29. PMID: 36367487
Article Published Date : Dec 04, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Inhibitory effect of Ulmus davidiana and Cornus officinalis extracts on osteoporotic bone loss.Mar 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2022 Mar 23 ;58(4). Epub 2022 Mar 23. PMID: 35454305
Article Published Date : Mar 22, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dogwood, Elm tree
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Lycopene prevents bone loss in ovariectomized rats and increases the number of osteocytes and osteoblasts.Apr 19, 2022

Pubmed Data : J Anat. 2022 Apr 20. Epub 2022 Apr 20. PMID: 35445391
Article Published Date : Apr 19, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lycopene
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Procyanidin B2 ameliorates the progression of osteoarthritis.Oct 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2022 Oct 20 ;113(Pt A):109336. Epub 2022 Oct 20. PMID: 36274486
Article Published Date : Oct 19, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Procyanidin B2
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Senomorphic agent pterostilbene ameliorates osteoarthritis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2022 ;14(8):5243-5262. Epub 2022 Aug 15. PMID: 36105068
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Osteoprotective
[+]

Sinensetin reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:713491. Epub 2021 Jul 16. PMID: 34335275
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Res. 2023 Jun ;192:106778. Epub 2023 Apr 23. PMID: 37094714
Article Published Date : May 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Oleuropein can not only improve the inflammatory and oxidative indexes of castrated rats but also prevent osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comput Math Methods Med. 2022 ;2022:9767113. Epub 2022 Aug 25. PMID: 36060661
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Osteoprotective
[+]

Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.Aug 31, 2020

Pubmed Data : Acta Histochem. 2020 Sep ;122(6):151596. Epub 2020 Jul 18. PMID: 32778234
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro.Aug 31, 2012

Pubmed Data : J Bone Miner Metab. 2012 Sep ;30(5):509-16. Epub 2012 Mar 13. PMID: 22407507
Article Published Date : Aug 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

The opposite effects of Antarctic krill oil and arachidonic acid-rich oil on bone resorption in ovariectomized mice.Aug 18, 2020

Pubmed Data : Food Funct. 2020 Aug 19 ;11(8):7048-7060. PMID: 32813003
Article Published Date : Aug 18, 2020
Study Type : Animal Study
Additional Links
Substances : Krill
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

10-gingerol suppresses osteoclastogenesis in RAW264.7 cells and zebrafish osteoporotic scales.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:588093. Epub 2021 Mar 3. PMID: 33748100
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

18β-glycyrrhetinic acid is a promising novel candidate in the treatment of osteoclast-related diseases such as postmenopausal osteoporosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:647. Epub 2018 Jun 20. PMID: 29973878
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

1α,25-Dihydroxyvitamin D3 ameliorates diabetes-induced bone loss by attenuating FoxO1-mediated autophagy.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biol Chem. 2021 Jan-Jun;296:100287. Epub 2021 Jan 13. PMID: 33450223
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Osteoprotective
[+]

2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside can be considered as a potential therapeutic for the treatment of postmenopausal osteoporosis.Aug 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Aug 28 ;19(9). Epub 2018 Aug 28. PMID: 30154383
Article Published Date : Aug 27, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Chondroprotective, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

A diet containing flaxseed flour contributed to bone mineral density and femur resistance.Apr 30, 2018

Pubmed Data : Nutrition. 2018 May ;49:48-50. Epub 2017 Dec 7. PMID: 29494999
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Pharmacological Actions : Osteoprotective
[+]

A positive effect of low-level laser energy on bone regeneration within a certain relationship between dose and output power was found.Jul 20, 2017

Pubmed Data : Photomed Laser Surg. 2017 Jul 21. Epub 2017 Jul 21. PMID: 28742438
Article Published Date : Jul 20, 2017
Study Type : Animal Study
Additional Links
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

A prebiotic mixture would be a useful tool to prevent the increase in bone loss associated with menopause and aging.Feb 28, 2019

Pubmed Data : Calcif Tissue Int. 2019 Mar ;104(3):301-312. Epub 2018 Nov 2. PMID: 30390108
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides, Prebiotics
Diseases : Aging, Menopausal Syndrome, Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

A protective effect of Curcuma comosa Roxb. on bone loss in estrogen deficient mice. Sep 01, 2011

Pubmed Data : J Ethnopharmacol. 2011 Sep 2 ;137(2):956-62. Epub 2011 Jul 6. PMID: 21762769
Article Published Date : Sep 01, 2011
Study Type : Animal Study
Additional Links
Substances : Curcuma Comosa
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

Acacetin inhibits RANKL-induced osteoclastogenesis and LPS-induced bone loss by modulating NFATc1 transcription.Oct 29, 2021

Pubmed Data : Biochem Biophys Res Commun. 2021 Oct 30 ;583:146-153. Epub 2021 Oct 30. PMID: 34763194
Article Published Date : Oct 29, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Acemannan is an effective bioactive agent for bone regeneration.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent Sci. 2018 Dec ;13(4):334-341. Epub 2018 Jul 20. PMID: 30895142
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Acetyl-11-keto-β-boswellic acid showed good antiosteoporotic activity.Oct 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 18 ;12(10). Epub 2020 Oct 18. PMID: 33081068
Article Published Date : Oct 17, 2020
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Adlay may be a helpful healthy food for osteoporosis prevention.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2013 Apr ;3(2):134-8. PMID: 24716168
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Adlay
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Administration of alpha-lipoic acid could maintain bone mass and bone strength in senile female rats with alcohol consumption.Oct 09, 2019

Pubmed Data : Z Gerontol Geriatr. 2019 Oct 10. Epub 2019 Oct 10. PMID: 31602508
Article Published Date : Oct 09, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Alcohol Toxicity , Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

All these results strongly indicate that puerarin exerts its anti-osteoprotic action independently of the ER-mediated pathway.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2012 ;58(3):202-9. PMID: 22878391
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Allicin alleviates lead-induced bone loss by preventing oxidative stress and osteoclastogenesis.Apr 20, 2020

Pubmed Data : Biol Trace Elem Res. 2020 Apr 21. Epub 2020 Apr 21. PMID: 32314144
Article Published Date : Apr 20, 2020
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Osteoprotective
Problem Substances : Lead
[+]

Allicin reversed the process of frailty in aging male Fischer 344 rats with osteoporosis.Sep 20, 2019

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Sep 21. Epub 2019 Sep 21. PMID: 31541608
Article Published Date : Sep 20, 2019
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Allyl sulfide promotes osteoblast differentiation and bone density.Mar 04, 2021

Pubmed Data : Biochem Biophys Res Commun. 2021 Mar 5 ;543:87-94. Epub 2021 Feb 6. PMID: 33556823
Article Published Date : Mar 04, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Garlic
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Alpha-Mangostin protects rat articular chondrocytes against IL-1β-induced inflammation and slows the progression of osteoarthritis.Oct 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Nov ;52:34-43. Epub 2017 Aug 31. PMID: 28858724
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Garcinia Mangostana
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Amelioration of osteoarthritis development by daily oral supplementation of royal Jelly.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2023 ;46(2):348-353. PMID: 36724964
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective , Prophylactic Agents
[+]

An anti-inflammatory composition of Boswellia serrata resin extracts alleviates pain and protects cartilage in monoiodoacetate-induced osteoarthritis in rats.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:7381625. Epub 2020 May 21. PMID: 32565872
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

An aqueous extract of Prunella vulgaris L. ameliorates cadmium-induced bone loss.Sep 30, 2023

Pubmed Data : Food Chem Toxicol. 2023 Oct ;180:114005. Epub 2023 Aug 26. PMID: 37640280
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Problem Substances : Cadmium
[+]

An ethanol extracts of Humulus lupulus could partially prevent ovariectomy-induced bone loss.Oct 14, 2017

Pubmed Data : Phytomedicine. 2017 Oct 15 ;34:50-58. Epub 2017 Aug 2. PMID: 28899509
Article Published Date : Oct 14, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Menopausal Syndrome, Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

An ethanolic extract of Urtica urens protects against the toxicity of imidacloprid on bone remodeling in rats.Jun 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Jul ;91:1022-1041. Epub 2017 May 16. PMID: 28531918
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants, Osteoprotective
Problem Substances : Pesticides
[+]

Anabolic therapy with Equisetum arvense along with bone mineralising nutrients in ovariectomized rat model of osteoporosis.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2016 May-Jun;48(3):312-5. PMID: 27298503
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Horsetail
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Analysis of anti-osteoporosis function of chlorogenic acid by gene microarray profiling in ovariectomy rat model.Jan 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2018 08 31 ;38(4). Epub 2018 Aug 31. PMID: 30054432
Article Published Date : Jan 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Andrographis paniculata ameliorates estrogen deficiency-related osteoporosis.Jan 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2023 Jan 31 ;11(2):52. PMID: 36819520
Article Published Date : Jan 30, 2023
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Andrographolide inhibits ovariectomy-induced bone loss.Nov 16, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 Nov 17 ;16(11):27470-81. Epub 2015 Nov 17. PMID: 26593901
Article Published Date : Nov 16, 2015
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2014 Feb ;171(3):663-75. PMID: 24125472
Article Published Date : Jan 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Anti-inflammatory activity of palmitoylethanolamide ameliorates osteoarthritis induced by monosodium iodoacetate.Aug 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Inflammopharmacology. 2021 Sep 1. Epub 2021 Sep 1. PMID: 34468900
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Osteoprotective , Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory and anti-osteoporotic potential of Lactobacillus plantarum A41 and L. fermentum SRK414 as probiotics.Aug 01, 2019

Pubmed Data : Probiotics Antimicrob Proteins. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31372901
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Anti-osteoporosis effect of fisetin against ovariectomy induced osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oleo Sci. 2022 ;71(1):105-118. PMID: 35013033
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Osteoprotective , Superoxide Dismutase Up-regulation
[+]

Anti-osteoporotic effects of polysaccharides isolated from persimmon leaves via osteoclastogenesis inhibition.Jul 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 13 ;10(7). Epub 2018 Jul 13. PMID: 30011853
Article Published Date : Jul 12, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Persimmon
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Anti-osteoporotic effects of Salvia miltiorrhiza Bunge EtOH extract both in ovariectomized and naturally menopausal mouse models.Apr 17, 2020

Pubmed Data : J Ethnopharmacol. 2020 Apr 18 ;258:112874. Epub 2020 Apr 18. PMID: 32311485
Article Published Date : Apr 17, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Antiosteoporosis and bone protective effect of dieckol against glucocorticoid-induced osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2022 ;13:932488. Epub 2022 Aug 19. PMID: 36060953
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Phlorotannins
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antrodia camphorata extract could promote osteogenesis and prevent bone loss.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2617868. Epub 2016 Apr 10. PMID: 27143981
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Bone Regeneration, Plant Extracts
[+]

Arctigenin prevents the progression of osteoarthritis.Feb 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Feb 24. Epub 2020 Feb 24. PMID: 32090454
Article Published Date : Feb 23, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Arctigenin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Arctigenin promotes bone formation involving PI3K/Akt/PPARγ signaling pathway.Dec 27, 2019

Pubmed Data : Chem Biol Drug Des. 2019 Dec 28. Epub 2019 Dec 28. PMID: 31883507
Article Published Date : Dec 27, 2019
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Artemisia annua extract prevents ovariectomy-induced bone loss.Dec 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 11 ;7(1):17332. Epub 2017 Dec 11. PMID: 29230013
Article Published Date : Dec 10, 2017
Study Type : Animal Study
Additional Links
Substances : Mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Artesunate attenuates experimental osteoarthritis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:685. Epub 2019 Jun 14. PMID: 31258481
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Ascorbic acid administration in the Akr1A1 knockout mice led to controllable osteoporosis.Jan 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jan 31 ;8(5):7357-7369. PMID: 28060768
Article Published Date : Jan 30, 2017
Study Type : Transgenic Animal Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Ascorbic acid induces osteoblast differentiation of human suspension mononuclear cells.Apr 30, 2014

Pubmed Data : Cytotherapy. 2014 May ;16(5):674-82. Epub 2013 Oct 29. PMID: 24176546
Article Published Date : Apr 30, 2014
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Asian Elm tree inner bark prevents articular cartilage deterioration.Dec 31, 2015

Pubmed Data : Menopause. 2016 02 ;23(2):197-208. PMID: 26506502
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Elm tree
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

Asiatic acid inhibits OVX-induced osteoporosis and osteoclastogenesis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:331. Epub 2020 Mar 27. PMID: 32292339
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Asiatic acid may be a potential anti-resorptive agent for postmenopausal osteoporosis.Aug 20, 2019

Pubmed Data : Calcif Tissue Int. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31435709
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
[+]

Asiatic acid protects articular cartilage through promoting chondrogenesis and inhibiting inflammation and hypertrophy in osteoarthritis.Sep 14, 2021

Pubmed Data : Eur J Pharmacol. 2021 Sep 15 ;907:174265. Epub 2021 Jun 24. PMID: 34174266
Article Published Date : Sep 14, 2021
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Astaxanthin attenuates irradiation-induced osteoporosis.Oct 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2022 Oct 26. Epub 2022 Oct 26. PMID: 36285709
Article Published Date : Oct 25, 2022
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Oxidative Stress, Radiation
Pharmacological Actions : Antioxidants, Osteoprotective , Radioprotective
[+]

Astaxanthin improves osteopenia caused by aldehyde-stress resulting from Aldh2 mutation due to impaired osteoblastogenesis. Jun 17, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jun 18 ;527(1):270-275. Epub 2020 May 4. PMID: 32446379
Article Published Date : Jun 17, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Astaxanthin may reduce alveolar bone loss by increasing osteoblastic activity and decrease osteoclastic activity in experimental periodontitis model.Oct 16, 2017

Pubmed Data : J Periodontal Res. 2017 Oct 17. Epub 2017 Oct 17. PMID: 29044575
Article Published Date : Oct 16, 2017
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Periodontitis
Pharmacological Actions : Osteoprotective
[+]

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis.Jan 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 12 ;23(12):8355-8368. Epub 2019 Oct 11. PMID: 31603626
Article Published Date : Jan 11, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Astragalin promotes osteoblastic differentiation in MC3T3-E1 cells and bone formation in vivo.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2019 ;10:228. Epub 2019 Apr 16. PMID: 31040823
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Astragaloside IV protects against iron loading-induced abnormal differentiation of bone marrow mesenchymal stem cells.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FEBS Open Bio. 2021 Jan 14. Epub 2021 Jan 14. PMID: 33445204
Article Published Date : Jan 13, 2021
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Iron Overload, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Baicalein alleviates osteoarthritis by protecting subchondral bone, inhibiting angiogenesis and synovial proliferation.May 02, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2021 May 3. Epub 2021 May 3. PMID: 33939310
Article Published Date : May 02, 2021
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Osteoarthritis
Pharmacological Actions : Angiogenesis Inhibitors, Osteoprotective
[+]

Baicalin attenuates dexamethasone-induced apoptosis of bone marrow mesenchymal stem cells.Feb 13, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2023 Feb 14. Epub 2023 Feb 14. PMID: 36804262
Article Published Date : Feb 13, 2023
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Beneficial effect of Cissus quadrangularis Linn. on osteopenia associated with streptozotocin-induced type 1 diabetes mellitus.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Sci. 2014 ;2014:483051. Epub 2014 Apr 7. PMID: 24803925
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Cissus quadrangularis
Diseases : Diabetes Mellitus: Type 1, Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Beneficial effects of paeoniflorin on osteoporosis induced by high-carbohydrate, high-fat diet-associated hyperlipidemia.Jan 14, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 04 15 ;498(4):981-987. Epub 2018 Mar 17. PMID: 29550473
Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : High Fat Diet, Hyperlipidemia, Osteoporosis
Pharmacological Actions : Hypolipidemic, Osteoprotective
[+]

Berberine alleviates oxidative stress in rats with osteoporosis.Oct 21, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bosn J Basic Med Sci. 2017 Oct 22. Epub 2017 Oct 22. PMID: 29055350
Article Published Date : Oct 21, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Berberine ameliorates periodontal bone loss by regulating gut microbiota.Sep 09, 2018

Pubmed Data : J Dent Res. 2018 Sep 10:22034518797275. Epub 2018 Sep 10. PMID: 30199654
Article Published Date : Sep 09, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoporosis, Periodontitis, Postmenopausal Disorders
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Berberine can be a potential therapeutic agent for osteoclast-related bone diseases.Mar 03, 2019

Pubmed Data : Am J Chin Med. 2019 Mar 4:1-17. Epub 2019 Mar 4. PMID: 30827151
Article Published Date : Mar 03, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berberine
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Osteoprotective
[+]

Berberine may be a potential treatment for controlling bone loss in diabetic osteoporosis.Sep 13, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep 14 ;108:280-287. Epub 2018 Sep 14. PMID: 30223099
Article Published Date : Sep 13, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetic Complications, Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Bergapten exerts inhibitory effects on diabetes-related osteoporosis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2016 Dec ;38(6):1661-1672. Epub 2016 Nov 2. PMID: 27840967
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Bergamot orange
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Beta-caryophyllene may be used as a therapeutic agent for the prevention and treatment of osteoporosis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):3602-3606. Epub 2016 Oct 18. PMID: 28105093
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Beta-Caryophyllene, Osteoporosis, Osteoprotective
[+]

Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency.Jul 31, 2022

Pubmed Data : Bone Joint Res. 2022 Aug ;11(8):528-540. PMID: 35920089
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Vitamin D Deficiency
Pharmacological Actions : Osteoprotective
[+]

Beta-cryptoxanthin might protect against periodontal disease.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2013 ;77(4):860-2. PMID: 23615426
Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cryptoxanthin
Diseases : Inflammation, Periodontitis
Pharmacological Actions : Osteoprotective
[+]

Better measurement of bone mechanical properties were observed for boron supplementation.Dec 31, 2005

Pubmed Data : Biofactors. 2006 ;28(3-4):195-201. PMID: 17473380
Article Published Date : Dec 31, 2005
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Blackcurrant supplementation improves trabecular bone mass in young but not aged mice.Nov 04, 2018

Pubmed Data : Nutrients. 2018 Nov 5 ;10(11). Epub 2018 Nov 5. PMID: 30400569
Article Published Date : Nov 04, 2018
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Bone strength is improved with genistein treatment in mice with diet-induced obesity.Oct 31, 2019

Pubmed Data : Curr Dev Nutr. 2019 Nov ;3(11):nzz121. Epub 2019 Oct 23. PMID: 31750414
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Obesity
Pharmacological Actions : Osteoprotective
[+]

Boron preserves bone mass in rats that have been exposed to intense exercise.Dec 31, 2001

Pubmed Data : J Clin Densitom. 2002 ;5(2):187-92. PMID: 12110762
Article Published Date : Dec 31, 2001
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bone Diseases
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Osteoprotective
[+]

Boron supplementation improves parameters related to bone strength and microstructure of cortical and trabecular bone in diabetic animals.Dec 31, 2016

Pubmed Data : J Trace Elem Med Biol. 2017 Jan ;39:169-175. Epub 2016 Oct 1. PMID: 27908411
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Diabetic Complications
Pharmacological Actions : Osteoprotective
[+]

Boswellia serrata extracts exhibits potential as a therapeutic agent for treating osteoarthritis.Sep 29, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2023 Sep 30 ;28(3):285-292. PMID: 37842260
Article Published Date : Sep 29, 2023
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bovine lactoferrin inhibits alveolar bone destruction in an orthodontic rat model with periodontitis.Apr 21, 2021

Pubmed Data : Ann Anat. 2021 Apr 22 ;237:151744. Epub 2021 Apr 22. PMID: 33895284
Article Published Date : Apr 21, 2021
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Periodontitis
Pharmacological Actions : Osteoprotective
[+]

Calendula officinalis reduced oxidative stress and bone loss and preserved collagen fibers in a periodontitis model.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2017 ;8:440. Epub 2017 Jun 28. PMID: 28701962
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Marigold
Diseases : Periodontitis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.Sep 30, 2017

Pubmed Data : J Mol Med (Berl). 2017 Oct ;95(10):1065-1076. Epub 2017 Jul 4. PMID: 28674855
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective
[+]

CBD administration attenuated spinal cord injury induced sublesional cancellous bone loss.May 03, 2017

Pubmed Data : Eur J Pharmacol. 2017 May 4. Epub 2017 May 4. PMID: 28479140
Article Published Date : May 03, 2017
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Spinal Cord Injuries
Pharmacological Actions : Osteoprotective
[+]

Chokeberry may be a promising natural agent for protection against the toxic action of cadmium in women chronically exposed to this metal.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Planta Med. 2016 May ;82(7):621-31. Epub 2016 Apr 20. PMID: 27096624
Article Published Date : Apr 30, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Cadmium Poisoning , Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Plant Extracts
Problem Substances : Cadmium
[+]

Chrysin alleviates alteration of bone-remodeling markers.Jul 20, 2021

Pubmed Data : Hum Exp Toxicol. 2021 Jul 21:9603271211033777. Epub 2021 Jul 21. PMID: 34289748
Article Published Date : Jul 20, 2021
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Chrysin attenuates high glucose-induced BMSC dysfunction.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2022 ;16:165-182. Epub 2022 Jan 13. PMID: 35058687
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Osteoprotective , Superoxide Dismutase Up-regulation
[+]

Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:724256. Epub 2021 Sep 29. PMID: 34658863
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Cohosh
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Co-administrated puerarin and zinc can partially reverse OVX-induced bone loss.Nov 30, 2016

Pubmed Data : Life Sci. 2016 Dec 1 ;166:20-26. Epub 2016 Sep 30. PMID: 27697446
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Puerarin, Zinc
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : bone loss, Osteoporosis, Ovariectomy-Induced Changes, Puerarin, zinc
[+]

Connectivity map analysis identifies fisetin as a treatment compound for osteoporosis.Feb 28, 2021

Pubmed Data : Curr Pharm Biotechnol. 2021 Mar 1. Epub 2021 Mar 1. PMID: 33645479
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Consumption of vitamin D2 enhanced mushrooms is associated with improved bone health.Jun 30, 2015

Pubmed Data : J Nutr Biochem. 2015 Jul ;26(7):696-703. Epub 2015 Mar 5. PMID: 25792284
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Mushrooms: All
Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

CoQ10 stimulates the proliferation and differentiation of BMSCs and is effective for the treatment of OVX induced osteoporosis.Dec 31, 2017

Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):400-407. Epub 2017 Oct 26. PMID: 29115467
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Crataegus pinnatifida Bunge could be a potential alternative medicine for bone diseases.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:5521562. Epub 2021 Mar 27. PMID: 33859705
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hawthorn
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Crocin attenuates metabolic syndrome-induced osteoporosis.Jun 30, 2019

Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12895. Epub 2019 May 15. PMID: 31353703
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Metabolic Syndrome X, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Curcuma longa rhizome and Boswellia serrata gum resin exerts anti-osteoarthritic effects.Nov 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 23 ;25(22). Epub 2020 Nov 23. PMID: 33238379
Article Published Date : Nov 22, 2020
Study Type : Animal Study
Additional Links
Substances : Frankincense, Terminalia chebula
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Dec 17. Epub 2019 Dec 17. PMID: 31845532
Article Published Date : Dec 16, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Deguelin inhibits RANKL-induced osteoclastogenesis in vitro and prevents inflammation-mediated bone loss in vivo.Feb 28, 2019

Pubmed Data : J Cell Physiol. 2019 Mar ;234(3):2719-2729. Epub 2018 Aug 5. PMID: 30078209
Article Published Date : Feb 28, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Deguelin
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

DHA exerts an anti-osteoclastogenic effect by suppressing the proliferation and differentiation of bone marrow-derived macrophages.Nov 08, 2016

Pubmed Data : Cell Signal. 2016 Nov 9 ;29:226-232. Epub 2016 Aug 9. PMID: 27836739
Article Published Date : Nov 08, 2016
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
[+]

Diallyl trisulfide ameliorates bone loss and alters specific gut microbiota and serum metabolites in natural aging mice.Aug 13, 2023

Pubmed Data : Food Funct. 2023 Aug 14 ;14(16):7642-7653. Epub 2023 Aug 14. PMID: 37540026
Article Published Date : Aug 13, 2023
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Aging, Osteoporosis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Dietary cordycepin can prevent bone loss caused by estrogen deficiency.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:423869. Epub 2015 Mar 22. PMID: 25874211
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Dietary flavonoid kaempferol inhibits glucocorticoid-induced bone loss by promoting osteoblast survival.Feb 12, 2018

Pubmed Data : Nutrition. 2018 Feb 13 ;53:64-76. Epub 2018 Feb 13. PMID: 29655780
Article Published Date : Feb 12, 2018
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Bone Fractures
Pharmacological Actions : Osteoprotective
[+]

Diosgenin can inhibit apoptosis and increase mitochondrial oxidative stress capacity of chondrocytes in mice with osteoarthritis.May 24, 2016

Pubmed Data : Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25 ;45(5):453-460. PMID: 28087904
Article Published Date : May 24, 2016
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Osteoprotective , Superoxide Dismutase Up-regulation
[+]

Diosgenin prevents bone loss on retinoic acid-induced osteoporosis.Jul 31, 2016

Pubmed Data : Ir J Med Sci. 2016 Aug ;185(3):581-7. Epub 2015 Jun 19. PMID: 26089290
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Diosgenin protects against alveolar bone loss in ovariectomized rats via regulating long non-coding RNAs.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Nov ;16(5):3939-3950. Epub 2018 Sep 3. PMID: 30344672
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteoprotective
[+]

Diosmetin inhibits osteoclast formation and differentiation and prevents LPS-induced osteolysis in mice.Jul 31, 2019

Pubmed Data : J Cell Physiol. 2019 Aug ;234(8):12701-12713. Epub 2018 Dec 4. PMID: 30515812
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Diosmetin
Diseases : Bone Diseases: Over-Active Osteoclasts, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Osteoprotective
[+]

Diosmin protects rats from chronic kidney disease-induced loss of bone mass.Feb 20, 2022

Pubmed Data : Food Funct. 2022 Feb 21 ;13(4):2184-2199. Epub 2022 Feb 21. PMID: 35119062
Article Published Date : Feb 20, 2022
Study Type : Animal Study
Additional Links
Substances : Diosmin
Diseases : Chronic Kidney Disease (CKD), Osteoporosis
Pharmacological Actions : Osteoprotective , Renoprotective
Additional Keywords : Phytotherapy
[+]

Dried and free flowing granules of Spinacia oleracea accelerate bone regeneration and alleviate postmenopausal osteoporosis.Dec 31, 2016

Pubmed Data : Menopause. 2017 06 ;24(6):686-698. PMID: 28118295
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Spinach
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration, Ovariectomy-Induced Changes, Plant Extracts
[+]

Echinacoside alleviates osteoarthritis in rats by activating the Nrf2-HO-1 signaling pathway.Jul 10, 2022

Pubmed Data : Immunopharmacol Immunotoxicol. 2022 Jul 11:1-10. Epub 2022 Jul 11. PMID: 35815581
Article Published Date : Jul 10, 2022
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Osteoprotective
[+]

Echinacoside inhibits osteoclast function by down-regulating PI3K/Akt/C-Fos to alleviate osteolysis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:930053. Epub 2022 Jun 24. PMID: 35814196
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy.Dec 31, 2010

Pubmed Data : Clin Ter. 2011 ;162(4):307-12. PMID: 21912817
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Cissus quadrangularis
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs, Ovariectomy-Induced Changes, Plant Extracts
[+]

Effective treatment of knee osteoarthritis using a nano-enabled drug acupuncture technology in mice.Aug 08, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Sci (Weinh). 2023 Aug 9:e2302586. Epub 2023 Aug 9. PMID: 37555294
Article Published Date : Aug 08, 2023
Study Type : Animal Study
Additional Links
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

Effects of icariin on modulating gut microbiota and regulating metabolite alterations to prevent bone loss in ovariectomized rat model.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2022 ;13:874849. Epub 2022 Mar 24. PMID: 35399950
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Osteoporosis: Age-Related
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Effects of Nigella sativa and human parathyroid hormone on bone mass and strength in diabetic rats.May 31, 2007

Pubmed Data : Biol Trace Elem Res. 2007 Jun ;116(3):321-8. PMID: 17709912
Article Published Date : May 31, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Effects of tocotrienol from Bixa orellana (annatto) on bone histomorphometry in a male osteoporosis model induced by buserelin.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:453-462. Epub 2018 Apr 24. PMID: 29674281
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Achiote
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

EGCG reversed GIO in rats by protecting osteoblasts by activating the Nrf2 signaling pathway.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:447. Epub 2018 May 9. PMID: 29867459
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
[+]

Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis.May 31, 2023

Pubmed Data : Phytomedicine. 2023 Jun ;114:154745. Epub 2023 Mar 6. PMID: 36931096
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Emodin suppresses IBD-induced osteoporosis by inhibiting osteoclast formation.Jan 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31934719
Article Published Date : Jan 13, 2020
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Inflammatory Bowel Diseases, Osteoporosis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Emodin suppresses the cadmium induced osteoporosis by inhibiting osteoclast formation.Aug 31, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Sep ;54:162-168. Epub 2017 Jul 18. PMID: 28738286
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Cadmium Poisoning , Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Engeletin ameliorated osteoarthritis in vitro and in vivo.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm Res. 2021 ;14:745-760. Epub 2021 Mar 9. PMID: 33727849
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Chondroprotective, Nrf2 activation, Osteoprotective
[+]

Eriodicyol inhibits osteoclast differentiation and ovariectomy-induced bone loss in vivo.Dec 09, 2015

Pubmed Data : Exp Cell Res. 2015 Dec 10 ;339(2):380-8. Epub 2015 Oct 9. PMID: 26450448
Article Published Date : Dec 09, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Eugenol and quercetin were revealed to have antioxidant, antidiabetic and osteoprotective effects.May 31, 2022

Pubmed Data : J Diabetes Metab Disord. 2022 Jun ;21(1):637-646. Epub 2022 Mar 12. PMID: 35673437
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol, Quercetin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Eugenol protects chondrocytes and articular cartilage.Jul 25, 2022

Pubmed Data : J Orthop Res. 2022 Jul 26. Epub 2022 Jul 26. PMID: 35880357
Article Published Date : Jul 25, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective, Interleukin-1 beta downregulation, Osteoprotective
[+]

Evaluation of anti-osteoporotic activity of butanolic fraction from Passiflora foetida in ovariectomy-induced bone loss in mice.Mar 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr ;88:804-813. Epub 2017 Feb 1. PMID: 28160755
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Fermented rice bran supplementation inhibits LPS-induced osteoclast formation and bone resorption.Jul 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jul 5 ;15(13). Epub 2023 Jul 5. PMID: 37447370
Article Published Date : Jul 04, 2023
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Rice Bran
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fermented rooibos may have a beneficial effect on bone health.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23. Epub 2018 May 23. PMID: 29790498
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Fisetin stimulates osteogenic activity and could be used as an effective strategy to prevent bone resorption.Jul 09, 2021

Pubmed Data : Biochem Pharmacol. 2021 Jul 10:114676. Epub 2021 Jul 10. PMID: 34256044
Article Published Date : Jul 09, 2021
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Fisetin: an integrated approach to identify a strategy promoting osteogenesis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:890693. Epub 2022 May 16. PMID: 35652047
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Osteoarthritis
Pharmacological Actions : Osteogenic, Osteoprotective
[+]

Folic acid attenuates high-fat diet-induced osteoporosis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:791880. Epub 2022 Jan 3. PMID: 35047504
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Folic Acid
Diseases : High Fat Diet, Osteoporosis
Pharmacological Actions : Antioxidants, Hypolipidemic, NF-kappaB Inhibitor, Osteoprotective
[+]

Formononetin enhances bone regeneration in a mouse model of cortical bone defect.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2017 Jun ;117(11):1511-1522. Epub 2017 Jul 10. PMID: 28689509
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Formononetin, Isoflavones
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Formononetin prevents ovariectomy-induced bone loss in rats.Mar 31, 2010

Pubmed Data : Arch Pharm Res. 2010 Apr ;33(4):625-32. Epub 2010 Apr 27. PMID: 20422373
Article Published Date : Mar 31, 2010
Study Type : Animal Study
Additional Links
Substances : Formononetin
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Galangin inhibits osteoclastic bone destruction and osteoclastogenesis.Jan 04, 2013

Pubmed Data : Eur J Pharmacol. 2013 Jan 5 ;698(1-3):57-66. Epub 2012 Sep 14. PMID: 22985747
Article Published Date : Jan 04, 2013
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Galangin mitigates glucocorticoid-induced osteoporosis by activating autophagy of bone marrow-derived mesenchymal stem cells.Jun 25, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2023 Jun 26 ;55(8):1275-1287. PMID: 37365870
Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Autophagy Up-regulation, Osteoprotective
[+]

Ganoderma lucidum immune modulator protein rLZ-8 could prevent and reverse bone loss in glucocorticoids-induced osteoporosis model. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:731. Epub 2020 May 19. PMID: 32508652
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.Jan 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FEBS Open Bio. 2020 11 ;10(11):2404-2416. Epub 2020 Oct 21. PMID: 33010109
Article Published Date : Jan 10, 2020
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Fluorosis
Pharmacological Actions : Antioxidants, Osteoprotective
Problem Substances : Fluoride
[+]

Gastrodin ameliorated rat cartilage degeneration in an osteoarthritis model of knee joints in vivo.Dec 31, 2017

Pubmed Data : Biomed Pharmacother. 2018 Jan ;97:642-651. Epub 2017 Nov 6. PMID: 29101808
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Inflammation, Osteoarthritis: Knee
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gastrodin was able to prevent or delay dexamethasone induced osteoporosis.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Apr ;41(4):2059-2069. Epub 2018 Jan 23. PMID: 29393365
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
Problem Substances : Dexamethasone
[+]

Genipin may be a promising preventative treatment to slow the degradation of cartilage.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Orthop Res. 2015 Nov ;33(11):1571-1579. Epub 2015 May 18. PMID: 25939430
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Cartilage Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Germinated pigmented rice improves glucose and bone metabolisms in ovariectomized rats.Oct 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Oct 21 ;8(10). Epub 2016 Oct 21. PMID: 27775654
Article Published Date : Oct 20, 2016
Study Type : Animal Study
Additional Links
Substances : Brown Rice: Pre-Germinated
Diseases : Hyperglycemia, Postmenopausal Disorders
Pharmacological Actions : Hypoglycemic Agents, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Gingko biloba-inspired lactone prevents osteoarthritis.Aug 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Res Ther. 2022 Aug 18 ;24(1):197. Epub 2022 Aug 18. PMID: 35982488
Article Published Date : Aug 17, 2022
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Ginkgolide B monotherapy reverses osteoporosis by regulating oxidative stress-mediated bone homeostasis.May 19, 2021

Pubmed Data : Free Radic Biol Med. 2021 May 20 ;168:234-246. Epub 2021 Mar 27. PMID: 33781894
Article Published Date : May 19, 2021
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Ginkgolide B promotes osteoblast differentiation via activation of canonical Wnt signalling and alleviates osteoporosis.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Aug ;23(8):5782-5793. Epub 2019 Jun 21. PMID: 31225702
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective , Wnt/β-catenin signaling pathway modulation
Additional Keywords : Ovariectomy-Induced Changes
[+]

Ginkgolide K delays the progression of osteoarthritis.Jul 31, 2023

Pubmed Data : Phytother Res. 2023 Aug 1. Epub 2023 Aug 1. PMID: 37527970
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Ginsenoside Rb 1 inhibits monoiodoacetate-induced osteoarthritis.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2021 Mar ;45(2):287-294. Epub 2020 Jan 21. PMID: 33841009
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Osteoprotective
[+]

Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis.May 24, 2022

Pubmed Data : Phytomedicine. 2022 May 25 ;104:154205. Epub 2022 May 25. PMID: 35716470
Article Published Date : May 24, 2022
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Ginsenoside Rc promotes bone formation in ovariectomy-induced osteoporosis.May 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 May 31 ;23(11). Epub 2022 May 31. PMID: 35682866
Article Published Date : May 30, 2022
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Ginsenoside Rg1/ADSCs supplemented with hyaluronic acid as the matrix improves rabbit temporomandibular joint osteoarthrosis.Mar 08, 2023

Pubmed Data : Biotechnol Genet Eng Rev. 2023 Mar 9:1-22. Epub 2023 Mar 9. PMID: 36892223
Article Published Date : Mar 08, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides, Hyaluronic Acid
Diseases : Osteoarthrosis
Pharmacological Actions : Osteoprotective
[+]

Ginsenoside Rg3 alleviates aluminum chloride-induced bone impairment in rats.Nov 02, 2021

Pubmed Data : J Agric Food Chem. 2021 Nov 3 ;69(43):12634-12644. Epub 2021 Oct 25. PMID: 34694773
Article Published Date : Nov 02, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Aluminum Toxicity
Pharmacological Actions : Osteoprotective , Transforming growth factor beta (TGF-β) upregulation
Problem Substances : Aluminum Chloride
[+]

Ginsenoside Rg5 prevents cartilage degradation in an osteoarthritis model.Feb 28, 2017

Pubmed Data : Oncol Rep. 2017 Mar ;37(3):1497-1502. Epub 2017 Jan 19. PMID: 28112382
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Ginsenoside-Rb1 prevents bone cartilage destruction.Mar 10, 2022

Pubmed Data : Phytomedicine. 2022 Mar 11 ;100:154039. Epub 2022 Mar 11. PMID: 35344713
Article Published Date : Mar 10, 2022
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Grape or apple juices have protective effects in bone tissue of rats exposed to cadmium.Mar 25, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 Mar 26. Epub 2018 Mar 26. PMID: 29582325
Article Published Date : Mar 25, 2018
Study Type : Animal Study
Additional Links
Substances : Apple, Grape
Diseases : Cadmium Poisoning
Pharmacological Actions : Osteoprotective
Problem Substances : Cadmium
[+]

Grape seed proanthocyanidin extract prevents bone loss via regulation of osteoclast differentiation, apoptosis, and proliferation.Oct 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 16 ;12(10). Epub 2020 Oct 16. PMID: 33081167
Article Published Date : Oct 15, 2020
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Grapefruit juice showed a beneficial anti-osteoporotic effect against prednisolone-induced osteoporosis.May 29, 2019

Pubmed Data : Cytotechnology. 2019 May 30. Epub 2019 May 30. PMID: 31147813
Article Published Date : May 29, 2019
Study Type : Animal Study
Additional Links
Substances : Grapefruit
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Green tea extract synergistically enhances the effectiveness of an antiresorptive drug on management of osteoporosis.Mar 31, 2021

Pubmed Data : Exp Ther Med. 2021 Apr ;21(4):328. Epub 2021 Feb 5. PMID: 33732301
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substance/Drug Synergy
[+]

Green tea supplementation benefits body composition and improves bone properties in obese female rats fed with high-fat diet and caloric restricted diet.Dec 01, 2015

Pubmed Data : Nutr Res. 2015 Dec ;35(12):1095-105. Epub 2015 Oct 5. PMID: 26525915
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Substances : Polyphenols
Diseases : Adiponectin: Low Levels, Female, Obesity, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Gut metabolite urolithin A inhibits osteoclastogenesis and senile osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:875611. Epub 2022 May 12. PMID: 35645801
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Urolithin A
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2018 ;8(9):2435-2446. Epub 2018 Mar 28. PMID: 29721090
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Harmine inhibits osteoclast differentiation and bone resorption in vitro and in vivo.Jan 14, 2011

Pubmed Data : Eur J Pharmacol. 2011 Jan 15 ;650(2-3):511-8. Epub 2010 Nov 1. PMID: 21047508
Article Published Date : Jan 14, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1028. Epub 2018 Sep 11. PMID: 30254586
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Hesperidin can prevent hydrogen peroxide-induced chondrocytes injury.Dec 16, 2018

Pubmed Data : Med Sci Monit. 2018 Dec 17 ;24:9177-9186. Epub 2018 Dec 17. PMID: 30557884
Article Published Date : Dec 16, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Hydrogen Peroxide Induced Toxicity, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hesperidin could be considered to be a beneficial treatment for preventing diabetic osteoporosis in growing age.Jan 25, 2017

Pubmed Data : Exp Toxicol Pathol. 2017 Jan 26. Epub 2017 Jan 26. PMID: 28132802
Article Published Date : Jan 25, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Diabetes Mellitus: Type 1, Osteoporosis
Pharmacological Actions : Osteoprotective , Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

High-dose diosgenin reduces bone loss in ovariectomized rats via attenuation of the RANKL/OPG ratio.Sep 24, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 Sep 25 ;15(9):17130-47. Epub 2014 Sep 25. PMID: 25257532
Article Published Date : Sep 24, 2014
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Hops extract and xanthohumol ameliorate bone loss induced by iron overload via activating Akt/GSK3β/Nrf2 pathway.Jan 31, 2022

Pubmed Data : J Bone Miner Metab. 2022 Feb 1. Epub 2022 Feb 1. PMID: 35106609
Article Published Date : Jan 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Iron Overload
Pharmacological Actions : Nrf2 activation, Osteoprotective
[+]

Humulus lupulus extract protects against senior osteoporosis.Jan 05, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Jan 6 ;28(2). Epub 2023 Jan 6. PMID: 36677642
Article Published Date : Jan 05, 2023
Study Type : Transgenic Animal Study
Additional Links
Substances : Hops
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Plant Extracts
[+]

Humulus lupulus L. extract may protect against bone loss, and have potentials in the treatment of osteoporosis.Mar 26, 2019

Pubmed Data : Chin J Integr Med. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30919241
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Hydroethanolic extracts of guava leaf appears to prevent osteoarthritis by inhibition of free radical formation in the knee joint.Aug 21, 2017

Pubmed Data : Biotech Histochem. 2017 Aug 22:1-8. Epub 2017 Aug 22. PMID: 28829233
Article Published Date : Aug 21, 2017
Study Type : Animal Study
Additional Links
Substances : Guava
Diseases : Osteoarthritis, Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Hydroxy-safflower yellow A alleviates osteoporosis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:734539. Epub 2021 Nov 5. PMID: 34803683
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Icariin alleviates glucocorticoid-induced osteoporosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:2982480. Epub 2020 May 17. PMID: 32508946
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Icariin attenuates thioacetamide‑induced bone loss via the RANKL‑p38/ERK‑NFAT signaling pathway.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2022 Apr ;25(4). Epub 2022 Feb 16. PMID: 35169865
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Icariin has a synergistic effect on the osteoinductivity of bone morphogenetic protein 2 at ectopic sites.Jan 09, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Orthop Surg. 2023 Jan 10. Epub 2023 Jan 10. PMID: 36628510
Article Published Date : Jan 09, 2023
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Icariin treatment rescues diabetes induced bone loss.Dec 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Dec 16 ;11(24). Epub 2022 Dec 16. PMID: 36552853
Article Published Date : Dec 15, 2022
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Identification of Andrographolide as a novel FABP4 inhibitor for osteoarthritis treatment.Aug 31, 2023

Pubmed Data : Phytomedicine. 2023 Sep ;118:154939. Epub 2023 Jun 20. PMID: 37354697
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Osteoarthritis
Pharmacological Actions : NF-kappaB Inhibitor, Osteoprotective
[+]

Inhibition of osteoclastogenesis and bone resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 1 ;5:17605. Epub 2015 Dec 1. PMID: 26620037
Article Published Date : Nov 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Interval running training improves age-related skeletal muscle wasting and bone loss: Experiments with ovariectomized rats.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Physiol. 2019 May ;104(5):691-703. Epub 2019 Mar 29. PMID: 30843284
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Exercise: Running
Pharmacological Actions : Osteoprotective , Prophylactic Agents
Additional Keywords : Ovariectomy-Induced Changes
[+]

Ipriflavone attenuates the degeneration of cartilage by blocking the Indian hedgehog pathway.Jan 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Res Ther. 2019 05 2 ;21(1):109. Epub 2019 May 2. PMID: 31046827
Article Published Date : Jan 01, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ipriflavone
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Isoquercitrin may be considered a safer alternative for managing osteoporosis.Dec 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Dec 15 ;865:172785. Epub 2019 Nov 9. PMID: 31712059
Article Published Date : Dec 14, 2019
Study Type : Animal Study
Additional Links
Substances : Isoquercitrin
Diseases : Osteoporosis
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, Osteoprotective
[+]

Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2023 ;11:1158812. Epub 2023 Apr 6. PMID: 37091976
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Osteoprotective
[+]

Kefir-fermented peptides prevent menopausal osteoporosis and mildly modulate the structure of the gut microbiota.Nov 08, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Nov 9 ;12(11). Epub 2020 Nov 9. PMID: 33182364
Article Published Date : Nov 08, 2020
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Osteoporosis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2023 Mar ;47(2):265-273. Epub 2022 Aug 31. PMID: 36926616
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Antibiotic Toxicity , Dysbiosis, Osteoporosis
Pharmacological Actions : Osteoprotective
Problem Substances : Antibiotics
[+]

L. casei (ATCC334), was able to significantly suppress the induction of adjuvant-induced arthritis and protect bones from destruction.Jan 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiome. 2019 07 17 ;7(1):107. Epub 2019 Jul 17. PMID: 31315667
Article Published Date : Jan 16, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus casei
Diseases : Dysbiosis, Rheumatoid Arthritis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

L. sativum ameliorates ovariectomy-induced bone injury in rats.Jul 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jul 13 ;12(7). Epub 2020 Jul 13. PMID: 32668691
Article Published Date : Jul 12, 2020
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum)
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Lactobacillus acidophilus has beneficial systemic effects that can potentially be developed as a safe osteoarthritis disease-modifying treatment.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2022 Jun 1 ;10(6). Epub 2022 Jun 1. PMID: 35740320
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus Acidophilus
Diseases : Dysbiosis, Osteoarthritis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Lactobacillus acidophilus supernatant alleviates osteoporosis by upregulating colonic SERT expression.May 31, 2023

Pubmed Data : Future Microbiol. 2023 Jun ;18:581-593. Epub 2023 Jul 10. PMID: 37424511
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus Acidophilus
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Lactobacillus plantarum LP45 inhibits the RANKL/OPG signaling pathway and prevents glucocorticoid-induced osteoporosis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2023 ;67. Epub 2023 Mar 24. PMID: 37056702
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Lactobacillus plantarum NK3 and Bifidobacterium longum NK49 may simultaneously alleviate bacterial vaginosis and osteoporosis.Sep 30, 2019

Pubmed Data : J Med Food. 2019 Oct ;22(10):1022-1031. Epub 2019 Aug 5. PMID: 31381476
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium Longum , Kimchi, Lactobacillus plantarum
Diseases : Bacterial Vaginosis, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus rhamnosus GG effectively supresses bone loss in a mouse model of induced periodontitis irrespective of the mode of administration.Nov 08, 2017

Pubmed Data : J Clin Periodontol. 2017 Nov 9. Epub 2017 Nov 9. PMID: 29121411
Article Published Date : Nov 08, 2017
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG
Diseases : Periodontitis
Pharmacological Actions : Osteoprotective
[+]

LBP1C-2 from Lycium barbarum alleviated age-related bone loss.Jun 14, 2023

Pubmed Data : Carbohydr Polym. 2023 Jun 15 ;310:120725. Epub 2023 Feb 23. PMID: 36925250
Article Published Date : Jun 14, 2023
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Licorice isoliquiritigenin-encapsulated mesoporous silica nanoparticles for osteoclast inhibition and bone loss prevention.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2019 ;9(18):5183-5199. Epub 2019 Jul 9. PMID: 31410209
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Liquiritigenin reduces blood glucose level and bone adverse effects in hyperglycemia.May 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 May 9 ;11(5). Epub 2019 May 9. PMID: 31075971
Article Published Date : May 08, 2019
Study Type : Animal Study
Additional Links
Substances : Liquiritigenin
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents, Osteoprotective
[+]

Long-term dietary intake of chia seed is associated with increased bone mineral content and improved hepatic and intestinal morphology.Jul 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 19 ;10(7). Epub 2018 Jul 19. PMID: 30029467
Article Published Date : Jul 18, 2018
Study Type : Animal Study
Additional Links
Substances : Chia
Diseases : Osteoporosis
Pharmacological Actions : Hepatoprotective, Hypolipidemic, Osteoprotective
[+]

Long-term electroacupuncture stimulation prevents osteoporosis in ovariectomised osteopaenic rats.Apr 05, 2018

Pubmed Data : Acupunct Med. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29625972
Article Published Date : Apr 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Osteoprotective
[+]

Low‑molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Feb ;15(2):890-898. Epub 2016 Dec 20. PMID: 28000877
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Luteolin protects chondrocytes from H2O2-induced oxidative injury and attenuates osteoarthritis progression.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:5635797. Epub 2022 Feb 1. PMID: 35154568
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Osteoarthritis, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation, Osteoprotective
[+]

Luteolin successfully improved periodontal health in a ligature-induced experimental periodontitis.May 21, 2019

Pubmed Data : J Periodontol. 2019 May 22. Epub 2019 May 22. PMID: 31115905
Article Published Date : May 21, 2019
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Periodontal Diseases
Pharmacological Actions : Matrix metalloproteinase-8 (MMP-8) inhibitor, Osteoprotective
[+]

Lycopene inhibits IL-1β-induced inflammation in mouse chondrocytes and mediates murine osteoarthritis.Mar 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2021 Mar 10. Epub 2021 Mar 10. PMID: 33751809
Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

M. alba stem extract exhibited an anti-nociceptive effect as well as cartilage protection.Dec 31, 2015

Pubmed Data : Pharmacology. 2016 ;98(5-6):209-216. Epub 2016 Jul 6. PMID: 27380522
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : White Mulberry
Diseases : Osteoarthritis
Pharmacological Actions : Antinoceceptive , Osteoprotective
Additional Keywords : Plant Extracts
[+]

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:1028932. Epub 2022 Oct 28. PMID: 36408274
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Matricaria chamomilla flower extract showed potential therapeutic benefits for osteoporosis.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Jul 1 ;11(7). Epub 2022 Jul 1. PMID: 35883807
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Methylsulfonylmethane increases the alveolar bone density of mandibles in aging female mice.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2021 ;12:708905. Epub 2021 Oct 4. PMID: 34671266
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : MSM (Methylsulfonylmethane)
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Montmorency tart cherry protects against age-related bone loss in female C57BL/6 mice.Oct 29, 2018

Pubmed Data : Eur J Nutr. 2018 Oct 30. Epub 2018 Oct 30. PMID: 30377814
Article Published Date : Oct 29, 2018
Study Type : Animal Study
Additional Links
Substances : Tart Cherry
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Morinda officinalis polysaccharide attenuates osteoporosis.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Orthop Surg (Hong Kong). 2022 Sep-Dec;30(3):10225536221130824. PMID: 36369661
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Indian Mulberry
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Polysaccharides
[+]

Morinda officinalis polysaccharide regulates rat bone mesenchymal stem cell osteogenic-adipogenic differentiation in osteoporosis.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2022 Jul ;38(7):675-685. Epub 2022 May 20. PMID: 35593324
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Indian Mulberry
Diseases : Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteoprotective
Additional Keywords : Polysaccharides
[+]

Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling.Feb 09, 2021

Pubmed Data : J Ethnopharmacol. 2021 Feb 10 ;266:113447. Epub 2020 Oct 3. PMID: 33022338
Article Published Date : Feb 09, 2021
Study Type : Animal Study
Additional Links
Substances : Dogwood
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, NF-kappaB Inhibitor, Osteoprotective
[+]

Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Prolif. 2020 Aug ;53(8):e12866. Epub 2020 Jul 9. PMID: 32643284
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Dogwood
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Morusin induces osteogenic differentiation of bone marrow mesenchymal stem cells by canonical Wnt/β-catenin pathway and prevents bone loss in an ovariectomized rat model.Jan 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stem Cell Res Ther. 2021 03 12 ;12(1):173. Epub 2021 Mar 12. PMID: 33712069
Article Published Date : Jan 11, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Mushroom extracts decrease bone resorption and improve bone formation.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(7):559-69. PMID: 27649725
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom, Oyster Mushroom, Shiitake Mushroom
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Plant Extracts
[+]

Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.Jun 04, 2018

Pubmed Data : Life Sci. 2018 Jun 5. Epub 2018 Jun 5. PMID: 29883721
Article Published Date : Jun 04, 2018
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Myricetin may be a potential agent for the treatment of periodontitis and osteoporosis.Mar 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Mar 22 ;17(3):422. Epub 2016 Mar 22. PMID: 27011174
Article Published Date : Mar 21, 2016
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis, Periodontitis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(7):4337-4347. Epub 2019 Jul 15. PMID: 31396339
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Nanoemulsified genistein and vitamin D mediated epigenetic regulation to inhibit osteoporosis.Aug 24, 2022

Pubmed Data : ACS Biomater Sci Eng. 2022 Aug 25. Epub 2022 Aug 25. PMID: 36005299
Article Published Date : Aug 24, 2022
Study Type : Animal Study
Additional Links
Substances : Genistein, Vitamin D
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Epigenetic Modification
[+]

Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Nov ;20(5):59. Epub 2020 Sep 4. PMID: 32952649
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Naringin promotes osteogenesis and ameliorates osteoporosis development.Sep 14, 2021

Pubmed Data : Clin Exp Pharmacol Physiol. 2021 Sep 15. Epub 2021 Sep 15. PMID: 34525226
Article Published Date : Sep 14, 2021
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Naringin protects against bone loss in steroid-treated inflammatory bowel disease in a rat model.Jul 14, 2018

Pubmed Data : Arch Biochem Biophys. 2018 Jul 15 ;650:22-29. Epub 2018 May 17. PMID: 29753722
Article Published Date : Jul 14, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : MicroRNA modulator, Osteoprotective
[+]

Natural product, bilobalide, improves joint health in rabbits with osteoarthritis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2022 ;9:1034623. Epub 2022 Oct 20. PMID: 36337189
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Osteoarthritis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Network pharmacology identifies fisetin as a treatment for osteoporosis.Apr 21, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Orthop Surg Res. 2023 Apr 22 ;18(1):312. Epub 2023 Apr 22. PMID: 37087476
Article Published Date : Apr 21, 2023
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective , Wnt/β-catenin signaling pathway modulation
[+]

Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2019 ;14:7839-7849. Epub 2019 Sep 26. PMID: 31576127
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Noni leaf extract protects against cerebral ischemia and osteoporosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1039364. Epub 2018 Mar 25. PMID: 29765488
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cerebral Ischemia, Osteoporosis
Pharmacological Actions : Neuroprotective Agents, Osteoprotective
[+]

Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats.Nov 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Invest. 2012 Dec ;92(12):1777-87. Epub 2012 Oct 8. PMID: 23044922
Article Published Date : Nov 30, 2012
Study Type : Animal Study
Additional Links
Substances : Nordihydroguaiaretic acid (NDGA)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Oleanolic acid and ursolic acid improve bone properties and calcium nalance and modulate vitamin D metabolism in aged female rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1435. Epub 2018 Dec 4. PMID: 30564129
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid, Ursolic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Oleanolic acid exerts inhibitory effects on the late stage of osteoclastogenesis and prevents bone loss in osteoprotegerin knockout mice.Jul 17, 2019

Pubmed Data : J Cell Biochem. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31318102
Article Published Date : Jul 17, 2019
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Osteoprotective
[+]

Olive leaf extract prevents cartilage degeneration in osteoarthritis.Mar 26, 2018

Pubmed Data : Biosci Biotechnol Biochem. 2018 Mar 27:1-6. Epub 2018 Mar 27. PMID: 29587623
Article Published Date : Mar 26, 2018
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Olive oil can effectively reduce bone loss in ovariectomized rats.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 May ;11(5):1881-1888. Epub 2016 Mar 10. PMID: 27168821
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Olive oil effectively mitigates ovariectomy-induced marrow adiposity assessed by MR spectroscopy in estrogen-deficient rabbits.Jan 25, 2021

Pubmed Data : Acta Radiol. 2021 Jan 26:284185120986937. Epub 2021 Jan 26. PMID: 33497273
Article Published Date : Jan 25, 2021
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain.Oct 19, 2021

Pubmed Data : Osteoarthritis Cartilage. 2021 Oct 20. Epub 2021 Oct 20. PMID: 34687898
Article Published Date : Oct 19, 2021
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia.Sep 30, 2017

Pubmed Data : Pharmacol Rep. 2017 Oct ;69(5):1113-1119. Epub 2017 May 13. PMID: 29031689
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression.Dec 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Dec 10 ;9(1):18741. Epub 2019 Dec 10. PMID: 31822750
Article Published Date : Dec 09, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Osteoarthritis
Pharmacological Actions : Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Osteoprotective
[+]

Oral administration of quercetin or its derivatives inhibit bone loss in animal model of osteoporosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:6080597. Epub 2020 Oct 27. PMID: 33194005
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Osteoprotective
[+]

Oridonin is a potential agent against inflammatory bone diseases.Aug 03, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Aug 4. Epub 2020 Aug 4. PMID: 32753731
Article Published Date : Aug 03, 2020
Study Type : Animal Study
Additional Links
Substances : Oridonin
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Orthosiphon stamineus ameliorated postmenopausal osteoporosis.Dec 31, 2017

Pubmed Data : Menopause. 2018 02 ;25(2):202-210. PMID: 28926512
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

Osteoprotective effects of kefir fortified with omega-3 and vitamin C.Jun 23, 2021

Pubmed Data : Int J Vitam Nutr Res. 2021 Jun 24:1-10. Epub 2021 Jun 24. PMID: 34162225
Article Published Date : Jun 23, 2021
Study Type : Animal Study
Additional Links
Substances : Kefir, Omega-3 Fatty Acids, Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective

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