Phase I Detoxification Enzyme Inducer

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9 Substances Researched for Phase I Detoxification Enzyme Inducer
NameACCKFocus
Acacia catechu12Locked
Broccoli Sprouts12Locked
Brussel sprouts12Locked
Carvacrol12Locked
Grape Seed Extract12Locked
Olive leaf extract12Locked
Sulforaphane12Locked
Thyme12Locked
Phloretin11Locked
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Phase I Detoxification Enzyme Inducer is a Sub of the following Topic

View the Evidence:
7 Abstracts with Phase I Detoxification Enzyme Inducer Research

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Acacia catechu extract affords hepato-protection against DMBA in rats through modulation of phase I, II and anti-oxidative enzymes.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(2):e90083. Epub 2014 Feb 27. PMID: 24587216
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Acacia catechu
Diseases : Chemically-Induced Liver Damage, Oxidative Stress
Pharmacological Actions : Hepatoprotective, Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Additional Keywords : Plant Extracts
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Broccoli sprout extract protected the liver from various types of xenobiotic substances through induction of detoxification enzymes and glutathione synthesis.Sep 20, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2015 Sep 21 ;21(35):10091-103. PMID: 26401074
Article Published Date : Sep 20, 2015
Study Type : Animal Study
Additional Links
Substances : Broccoli Sprouts
Diseases : Acetaminophen (Tylenol) Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective, Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Additional Keywords : Gene Expression Regulation, Plant Extracts
Problem Substances : Acetaminophen
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Brussel sprouts induce detoxifying enzymes. Aug 01, 2010

Pubmed Data : J Food Sci. 2010 Aug 1;75(6):H190-9. PMID: 20722931
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Brussel sprouts, Sulforaphane
Diseases : Chemical Exposure, Intoxication
Pharmacological Actions : Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Additional Keywords : Isothiocyanates, Plant Extracts
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Grape seed extract prevents chlorpyrifos-induced toxicity in rat liver through the modulation of phase I detoxification pathway.Feb 29, 2024

Pubmed Data : Environ Sci Pollut Res Int. 2024 Mar ;31(12):18566-18578. Epub 2024 Feb 13. PMID: 38349500
Article Published Date : Feb 29, 2024
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Chemically-Induced Liver Damage, Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Phase I Detoxification Enzyme Inducer
Problem Substances : Chlorpyrifos
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Olive leaf extract influences liver microsomal detoxifying enzymes in rats orally exposed to 2-amino-l-methyI-6-phenyI-imidazo pyridine.Sep 30, 2022

Pubmed Data : Environ Sci Pollut Res Int. 2022 Oct 1. Epub 2022 Oct 1. PMID: 36181589
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Cancers: All, Oxidative Stress
Pharmacological Actions : Antioxidants, Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Problem Substances : Polycyclic aromatic hydrocarbon
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Thyme and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver.Jan 01, 2005

Pubmed Data : J Med Food. 2005;8(2):184-9. PMID: 16117610
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thyme
Diseases : Xenobiotic Exposures
Pharmacological Actions : Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Additional Keywords : Plant Extracts
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Phloretin has possible chemopreventive role in which modulating the antioxidant and detoxification enzyme status.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Int. 2014 May ;21(2):179-85. PMID: 25253928
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Phloretin
Diseases : Oral Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer

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