PI3K-AKT inhibitor

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5 Substances Researched for PI3K-AKT inhibitor
NameACCKFocus
Broccoli Sprouts12Locked
Sulforaphane12Locked
Tomato12Locked
Curcumin11Locked
Tangeretin 11Locked

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4 Abstracts with PI3K-AKT inhibitor Research

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Sulforaphane exhibits antiproliferative, apoptotic, anti-inflammatory, and anti-angiogenic properties and ameliorates a rat model of endometriosis.Apr 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2019 Apr-Jun;17(2):1559325819855538. Epub 2019 Jun 11. PMID: 31217757
Article Published Date : Apr 01, 2019
Study Type : Animal Study
Additional Links
Substances : Broccoli Sprouts, Sulforaphane
Diseases : Endometriosis
Pharmacological Actions : Anti-Angiogenic, Anti Inflammatory, Antiproliferative , Apoptotic, Interferon Gamma Reducer, Interleukin-10 downregulation, PI3K-AKT inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Cytokines, Inflammation, Interleukin-6 Downregulation, women's health
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The synergistic anti cancer effects of paclitaxel and α-tomatine may be beneficial for refractory prostate cancer treatment.Nov 14, 2013

Pubmed Data : Phytomedicine. 2013 Nov 15 ;20(14):1297-305. Epub 2013 Aug 4. PMID: 23920276
Article Published Date : Nov 14, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tomato
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, PI3K-AKT inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Plant Extracts, Significant Treatment Outcome
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Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT.Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2012 Nov ;30(5):1021-8. Epub 2012 Aug 20. PMID: 22922731
Article Published Date : Oct 31, 2012
Study Type : In Vitro Study, Viral
Additional Links
Substances : Curcumin
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents, Heme oxygenase-1 inducer, PI3K-AKT inhibitor
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Tangeretin pre-exposure can overcome resistance of human ovarian cancer cells to growth inhibition by cisplatin.Nov 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Res. 2009 Dec 1 ;69(23):8910-7. Epub 2009 Nov 10. PMID: 19903849
Article Published Date : Nov 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin
Diseases : Cancers: Drug Resistant, Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor, PI3K-AKT inhibitor
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Oncogene Proteins

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