Selective estrogen enzyme modulator (SEEM)

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7 Substances Researched for Selective estrogen enzyme modulator (SEEM)
NameACCKFocus
Flaxseed12Locked
Milk Thistle12Locked
Pomegranate22Locked
Apigenin11Locked
Bee Propolis11Locked
CLA (Conjugated Linoleic Acid)11Locked
Melatonin11Locked

View the Evidence:
7 Abstracts with Selective estrogen enzyme modulator (SEEM) Research

[+]

Dietary flaxseed lignan or oil increases the breast cancer inhibitory effects of Tamoxifen. Nov 01, 2006

Pubmed Data : Biol Psychiatry. 2006 Nov 1;60(9):987-90. Epub 2006 Feb 24. PMID: 19904759
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Breast Cancer
Pharmacological Actions : Selective estrogen enzyme modulator (SEEM), Selective Estrogen Receptor Modulators
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Silymarin exhibits antiosteoporotic and selective estrogen receptor modulator activity in ovariectomized rats. Feb 01, 2010

Pubmed Data : Phytomedicine. 2010 Feb;17(2):116-25. Epub 2009 Jul 3. PMID: 19577454
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Milk Thistle
Diseases : Osteoporosis
Pharmacological Actions : Selective estrogen enzyme modulator (SEEM), Selective Estrogen Receptor Modulators
Additional Keywords : Estrogen Receptor Beta, Plant Extracts
[+]

Apigenin inhibits antiestrogen-resistant breast cancer cell growth. Nov 01, 2006

Pubmed Data : J Pineal Res. 2006 Nov;41(4):358-62. PMID: 18645020
Article Published Date : Nov 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Antiproliferative , Estrogen Receptor Modulators, Selective estrogen enzyme modulator (SEEM)
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Bee propolis contains a component which is a novel selective estrogen receptor modulator. Feb 01, 2010

Pubmed Data : Phytother Res. 2010 Feb;24(2):295-300. PMID: 19655397
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Pharmacological Actions : Antiproliferative , Estrogen Receptor Modulators, Selective estrogen enzyme modulator (SEEM)
[+]

Melatonin's role as a Selective Estrogen Enzyme Modulator (SEEM) indicates that it may have a therapeutic role in estrogen-dependent mammary tumors. Dec 01, 2008

Pubmed Data : Curr Cancer Drug Targets. 2008 Dec;8(8):691-702. PMID: 19075592
Article Published Date : Dec 01, 2008
Study Type : Commentary
Additional Links
Substances : Melatonin
Diseases : Breast Cancer
Pharmacological Actions : Selective estrogen enzyme modulator (SEEM)
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Pomegranate seed compounds have estrogen receptor enzyme modulating activity.Aug 01, 2007

Pubmed Data : Atherosclerosis. 2007 Aug;193(2):277-82. Epub 2006 Sep 29. PMID: 20136514
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : CLA (Conjugated Linoleic Acid), Pomegranate
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Estrogen Receptor Modulators, Selective estrogen enzyme modulator (SEEM), Selective Estrogen Receptor Modulators
Additional Keywords : Estrogen Receptor Beta
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Unlike tamoxifen and estradiol pomegranate exerts selective estrogen receptor modulator activity without uterotrophic properties.Aug 10, 2011

Pubmed Data : J Nutr Biochem. 2011 Aug 10. Epub 2011 Aug 10. PMID: 21839626
Article Published Date : Aug 10, 2011
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate
Diseases : Estrogen Deficiency, Estrogen Dominance
Pharmacological Actions : Selective estrogen enzyme modulator (SEEM)
Additional Keywords : HRT Alternatives, Superiority of Natural Substances versus Drugs
Problem Substances : 17beta-estradiol, Tamoxifen
Adverse Pharmacological Actions : Uterotrophic

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