Telomerase Upregulation

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23 Substances Researched for Telomerase Upregulation
NameACCKFocus
Vitamin E331Locked
Cynanchum Auriculatum120Locked
Vitamin C212Locked
Multivitamin110Locked
Vitamin D15Locked
Resveratrol33Locked
Astragalus22Locked
Cynomorium songaricum12Locked
Estradiol (E(2))22Locked
Purslane12Locked
TA-65 (Astragalus compound)12Locked
Traditional Chinese Medicine: Sijunzi Decoction12Locked
Chlorella (Algae)11Locked
Cycloastragenol11Locked
Ginkgo biloba11Locked
HDTIC-1 11Locked
HDTIC-211Locked
Melatonin11Locked
Pterostilbene11Locked
Silymarin11Locked
Spirulina11Locked
Tocotrienol: Gamma11Locked
Turmeric11Locked

View the Evidence:
34 Abstracts with Telomerase Upregulation Research

[+]

Cynanchum auriculatum in combination with vitamin E exhibits anti-aging properties. Dec 01, 2007

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(23):2511-4. PMID: 18330246
Article Published Date : Dec 01, 2007
Study Type : Meta Analysis
Additional Links
Substances : Cynanchum Auriculatum, Vitamin E
Diseases : Aging
Pharmacological Actions : Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Telomerase Upregulation
[+]

Mindfulness meditation leads to increased telomerase activity in peripheral blood mononuclear cells.Mar 31, 2014

Pubmed Data : Psychoneuroendocrinology. 2014 Apr ;42:45-8. Epub 2014 Jan 7. PMID: 24636500
Article Published Date : Mar 31, 2014
Study Type : Meta Analysis
Additional Links
Therapeutic Actions : Meditation
Pharmacological Actions : Telomerase Upregulation
[+]

Comprehensive lifestyle changes significantly increase telomerase activity and consequently telomere maintenance capacity in human immune-system cells. Nov 01, 2008

Pubmed Data : Lancet Oncol. 2008 Nov;9(11):1048-57. Epub 2008 Sep 15. PMID: 18799354
Article Published Date : Nov 01, 2008
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Lifestyle Changes: Positive
Pharmacological Actions : Telomerase Upregulation
[+]

Influence of mindfulness-based stress reduction on telomerase activity in women with breast cancer.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Res Nurs. 2014 Oct ;16(4):438-47. Epub 2014 Jan 30. PMID: 24486564
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Therapeutic Actions : Meditation
Pharmacological Actions : Telomerase Upregulation
[+]

Long-term endurance exercise training may provide a protective effect on muscle telomere length in older people.Dec 31, 2011

Pubmed Data : PLoS One. 2012 ;7(12):e52769. Epub 2012 Dec 26. PMID: 23300766
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Exercise: Endurance
Pharmacological Actions : Telomerase Upregulation, Telomere Protective
[+]

Loving-Kindness Meditation practice associated with longer telomeres in women.Apr 18, 2013

Pubmed Data : Brain Behav Immun. 2013 Apr 19. Epub 2013 Apr 19. PMID: 23602876
Article Published Date : Apr 18, 2013
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Kindness, Meditation
Pharmacological Actions : Telomerase Upregulation, Telomere Protective
[+]

Meditation is associated with increased telomerase activity associated with cell longevity. Oct 29, 2010

Pubmed Data : Psychoneuroendocrinology. 2010 Oct 29. Epub 2010 Oct 29. PMID: 21035949
Article Published Date : Oct 29, 2010
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Meditation
Pharmacological Actions : Telomerase Upregulation
[+]

Multivitamin use is associated with longer telomere length in women.Nov 01, 2002

Pubmed Data : Hepatogastroenterology. 2002 Nov-Dec;49(48):1571-5. PMID: 19279081
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : Multivitamin, Vitamin C, Vitamin E
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
[+]

"Vitamin D may improve telomere maintenance and prevent cell senescence and counteract obesity-induced acceleration of cellular aging."Jun 01, 2012

Pubmed Data : Int J Obes (Lond). 2012 Jun ;36(6):805-9. Epub 2011 Oct 11. PMID: 21986705
Article Published Date : Jun 01, 2012
Study Type : Human In Vitro
Additional Links
Substances : Vitamin D
Diseases : African-American Specific Deficiencies/Diseases, Aging, Obesity
Pharmacological Actions : Telomerase Upregulation
[+]

An aqueous extract of purslane has anti-anging activity. Apr 15, 2009

Pubmed Data : Phytother Res. 2009 Apr 15. PMID: 19367671
Article Published Date : Apr 15, 2009
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
Additional Keywords : Upregulation of Telemere Length
[+]

Cynomorium songaricum polysaccharide may exert an anti-aging effect by increase telomere length of aged mice.May 01, 2009

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 May;34(10):1257-60. PMID: 19673390
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Cynomorium songaricum
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
[+]

Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia.Jul 01, 2011

Pubmed Data : Brain Behav Immun. 2011 Jul;25(5):971-80. Epub 2010 Oct 21. PMID: 20970493
Article Published Date : Jul 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Schizophrenia
Therapeutic Actions : Exercise
Pharmacological Actions : Neuritogenic, Telomerase Upregulation
[+]

Sijunzi decoction exhibits anti-aging properties, including increases in telomerase activity.May 01, 2006

Pubmed Data : Biosci Biotechnol Biochem. 2006 May;70(5):1118-26. PMID: 16025969
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Traditional Chinese Medicine: Sijunzi Decoction
Diseases : Aging
Pharmacological Actions : Antioxidants, Telomerase Upregulation
[+]

TA-65 dietary supplementation in female mice leads to an improvement of certain health-span indicators including glucose tolerance, osteoporosis and skin fitness, without significantly increasing global cancer incidence.Jul 31, 2011

Pubmed Data : Aging Cell. 2011 Aug ;10(4):604-21. Epub 2011 Apr 14. PMID: 21426483
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : TA-65 (Astragalus compound)
Diseases : Aging, DNA damage, Osteoporosis
Pharmacological Actions : Anticarcinogenic Agents, Telomerase Upregulation
[+]

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.Jan 06, 2011

Pubmed Data : Nature. 2011 Jan 6;469(7328):102-6. Epub 2010 Nov 28. PMID: 21113150
Article Published Date : Jan 06, 2011
Study Type : Animal Study
Additional Links
Diseases : Aging
Pharmacological Actions : Antiproliferative , Telomerase Upregulation
Additional Keywords : Drug: Tamoxifen
[+]

Vitamin c treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity.Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Physiol. 2012 Sep ;227(9):3216-24. PMID: 22105792
Article Published Date : Aug 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C
Pharmacological Actions : Regenerative, Telomerase Upregulation
[+]

A compound found within astragalus called cycloastragenol may enhance immune function by retarding telomere loss in white blood cells associated with chronic viral infection.Nov 15, 2008

Pubmed Data : J Immunol. 2008 Nov 15;181(10):7400-6. PMID: 18981163
Article Published Date : Nov 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : Astragalus, Cycloastragenol
Diseases : HIV Infections
Pharmacological Actions : Enzyme Inhibitors, Immunomodulatory, Telomerase Upregulation
Additional Keywords : Upregulation of Telemere Length
[+]

Alpha-tocopherol prevents hydrogen peroxide-induced DNA damage and telomere shortening and upregulates telomerase activity in human skin cells.Jun 01, 2010

Pubmed Data : Planta Med. 2010 Jun;76(9):869-75. Epub 2010 Jan 28. PMID: 20112180
Article Published Date : Jun 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E
Diseases : Aging, Aging Skin, DNA damage, Oxidative Stress
Pharmacological Actions : Telomerase Upregulation
[+]

Astragalus contains compounds which slow cell aging through reduced telomere shortening rate, oxidative stress and increasing DNA repair ability.Jan 01, 2010

Pubmed Data : DNA Cell Biol. 2010 Jan;29(1):33-9. PMID: 19839736
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Astragalus, HDTIC-1 , HDTIC-2
Diseases : Aging, DNA damage, Oxidative Stress
Pharmacological Actions : Telomerase Upregulation
[+]

Chlorella exhibits bioprotective properties against experimentally induced DNA damage and telomerase inhibition. Jan 01, 2009

Pubmed Data : Afr J Tradit Complement Altern Med. 2009;6(4):560-72. Epub 2009 Jul 3. PMID: 20606778
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Aging, DNA damage, Oxidative Stress
Pharmacological Actions : Genoprotective, Telomerase Upregulation
[+]

Dual effect of Sapogenins extracted from Spirulina platensis on telomerase activity in two different cell lines.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Biol Res Commun. 2021 Mar ;10(1):1-4. PMID: 33681391
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Spirulina
Diseases : Aging, Breast Cancer, Skin Cancer
Pharmacological Actions : Telomerase Inhibitor, Telomerase Upregulation
[+]

Effects of water extract of Curcuma longa roots on immunity and telomerase function.May 11, 2017

Pubmed Data : J Complement Integr Med. 2017 May 12 ;14(3). Epub 2017 May 12. PMID: 28889732
Article Published Date : May 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Turmeric
Pharmacological Actions : Immunomodulatory, Telomerase Upregulation
Additional Keywords : Plant Extracts
[+]

Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity.Sep 01, 2005

Pubmed Data : J Hypertens. 2005 Sep;23(9):1699-706. PMID: 16093915
Article Published Date : Sep 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Estradiol (E(2))
Diseases : Aging, Endothelial Dysfunction
Pharmacological Actions : Antiproliferative , Enzyme Inhibitors, Telomerase Upregulation, Vascular Endothelial Growth Factor A Inhibitor
[+]

Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity. Feb 01, 2010

Pubmed Data : Ther Adv Cardiovasc Dis. 2010 Feb;4(1):55-69. Epub 2009 Dec 4. PMID: 19965898
Article Published Date : Feb 01, 2010
Study Type : Review
Additional Links
Substances : Estradiol (E(2))
Diseases : Aging, Endothelial Dysfunction
Pharmacological Actions : Telomerase Upregulation
[+]

Gamma-tocotrienol protects against oxidative stress-induced cellular ageing by modulating the telomere length possibly via telomerase.Jan 01, 2010

Pubmed Data : Oxid Med Cell Longev. 2010 Jan-Feb;3(1):35-43. PMID: 20716926
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Gamma
Diseases : Aging, Oxidative Stress
Pharmacological Actions : Antioxidants, Telomerase Upregulation
Additional Keywords : Telomere Length, Upregulation of Telemere Length
[+]

Ginkgo biloba extract reduces endothelial progenitor-cell aging through augmentation of telomerase activity.Feb 01, 2007

Pubmed Data : J Cardiovasc Pharmacol. 2007 Feb;49(2):111-5. PMID: 17312453
Article Published Date : Feb 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aging, Endothelial Dysfunction
Pharmacological Actions : Telomerase Upregulation
Additional Keywords : Plant Extracts
[+]

Melatonin may treat or prevent age-related macular degeneration through stimulation of telomerase activity.Jan 01, 2011

Pubmed Data : Med Hypotheses. 2011 Jan;76(1):79-85. Epub 2010 Sep 29. PMID: 20884126
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Macular Degeneration
Pharmacological Actions : Enzyme Inhibitors, Telomerase Upregulation, Vascular Endothelial Growth Factor A Inhibitor
[+]

Rejuvenation of aged tissues may be possible through telomerase reactivation.Dec 01, 2010

Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):749-54. PMID: 21226558
Article Published Date : Dec 01, 2010
Study Type : Review
Additional Links
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
[+]

Resveratrol and pterostilbene significantly inhibit the proliferation of both MDA-MB-157 and HCC1806 breast cancer cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2015 ;15:672. Epub 2015 Oct 12. PMID: 26459286
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene, Resveratrol
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Telomerase Upregulation
Additional Keywords : Epigenetic Modification In Cancer, Natural Substance Synergy
[+]

Resveratrol may have therapeutic value in Werner syndrome.Feb 01, 2011

Pubmed Data : Curr Aging Sci. 2011 Feb 1;4(1):1-7. PMID: 21204775
Article Published Date : Feb 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Werner Syndrome
Pharmacological Actions : Telomerase Upregulation
[+]

Resveratrol reduces aging via telomerase activation.Jun 30, 2008

Pubmed Data : Br J Pharmacol. 2008 Jun 30. PMID: 18587418
Article Published Date : Jun 30, 2008
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
[+]

Silymarin inhibits endothelial progenitor cell aging through telomerase upregulation. Aug 09, 2002

Pubmed Data : Life Sci. 2002 Aug 9;71(12):1385-96. PMID: 20838231
Article Published Date : Aug 09, 2002
Study Type : In Vitro Study
Additional Links
Substances : Silymarin
Diseases : Aging
Pharmacological Actions : Telomerase Upregulation
[+]

Telomerase activity and its association with psychological stress, mental disorders, lifestyle factors and interventions.Jan 31, 2016

Pubmed Data : Psychoneuroendocrinology. 2016 Feb ;64:150-63. Epub 2015 Nov 25. PMID: 26677763
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Diseases : Depression
Therapeutic Actions : Exercise, Meditation , Yoga
Pharmacological Actions : Telomerase Inhibitor, Telomerase Upregulation
[+]

Telomere lengths remain long (near that of infancy) in the human heart, brain, eyes (retina), testes, and ovaries. Acupuncture and acupressure reduce telomerase activity in tumors and increase telomerase in normal tissue. Jun 01, 1991

Pubmed Data : Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1606-8. PMID: 10193703
Article Published Date : Jun 01, 1991
Study Type : Review
Additional Links
Diseases : Aging
Therapeutic Actions : Acupressure, Acupuncture
Pharmacological Actions : Telomerase Inhibitor, Telomerase Upregulation

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