Vascular Endothelial Growth Factor A Inhibitor

Name	AC	CK
Curcumin	19	26
Arginine	2	12
Enterolactone	2	12
Flaxseed	2	12
Lignans	2	12
Chinese Herbal Formula: Shenyi Capsule	1	10
Diosmin	1	10
Resveratrol	9	10
Green Tea	4	7
Quercetin	4	6
Amurensin G	1	5
Lysine	3	5
Proline	3	5
Vitamin C	3	5
Genistein	3	4
Milk Thistle	2	4
Thymoquinone	3	4
Inositol Hexaphosphate	2	3
Angelica	1	2
Apigenin	1	2
Asafoetida	1	2
Ashwagandha	1	2
Bacopa	1	2
Cannabidiol	1	2
Cannabinoids	1	2
Carnitine	1	2
Chinese Skullcap	1	2
Emodin	1	2
Enterodiol	1	2
Flavonoids	1	2
Fucoidan	1	2
Gac	1	2
Ginseng (Korean)	1	2
Ginsenosides	1	2
Isothiocyanates	1	2
Ligustrazine	1	2
Luteolin	2	2
Lycopene	1	2
Nigella sativa (aka Black Seed)	1	2
Oleuropein	1	2
Oridonin	1	2
Protandim	1	2
Prunella vulgaris	1	2
Red Sage	1	2
Red Yeast Rice	1	2
Silibinin	1	2
Soy	1	2
Traditional Chinese Medicine: Mylabris	1	2
Turmeric	1	2
Acai	1	1
Astragaloside	1	1
Avenanthramides	1	1
Beet	1	1
Berbamine	1	1
Bufalin	1	1
Cannabinoids: Synthetic	1	1
Catechin	1	1
Corn Silk	1	1
Estradiol (E(2))	1	1
Evodiamine	1	1
Genipin	1	1
Isoliquiritigenin	1	1
Lactoferrin	1	1
Melatonin	1	1
NAC (N-acetyl-L-cysteine)	1	1
Oats	1	1
Olive leaf extract	1	1
Picropodophyllin	1	1
Polyphenols	1	1
Pterostilbene	1	1
Rutin	1	1
Stilbenes	1	1
Tripterygium wilfordii	1	1
Triptolide	1	1
Vitamin E	1	1
Water: Electrolyzed Reduced	1	1

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Sesamin inhibits hypoxia-stimulated angiogenesis.Aug 29, 2022

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Pubmed Data : Food Funct. 2022 Aug 30 ;13(17):8989-8997. Epub 2022 Aug 30. PMID: 35939045

Article Published Date : Aug 29, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Sesamin

Diseases : Colorectal Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor A Inhibitor

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Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Theranostics. 2020 ;10(15):6839-6853. Epub 2020 May 22. PMID: 32550907

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Emodin

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor A Inhibitor

[+]

"Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization."Mar 01, 2010

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Pubmed Data : Arterioscler Thromb Vasc Biol. 2010 Mar ;30(3):426-35. Epub 2010 Jan 7. PMID: 20056909

Article Published Date : Mar 01, 2010

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Pubmed Data : Mol Cell Biochem. 2005 May;273(1-2):57-67. PMID: 16013440

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Pubmed Data : Biochem Biophys Res Commun. 2007 Sep 21;361(2):528-32. Epub 2007 Jul 23. PMID: 17662242

Article Published Date : Sep 21, 2007

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Vascular Endothelial Growth Factor A Inhibitor

[+]

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.Dec 01, 2009

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Pubmed Data : Cancer Res. 2009 Dec 1;69(23):8958-66. Epub 2009 Nov 10. PMID: 19903839

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Mar 31. Epub 2017 Mar 31. PMID: 28410190

Article Published Date : Mar 30, 2017

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : High Fat Diet, Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor D Inhibitor

[+]

DIM is a possible treatment option for inflammation of the intestine and associated angiogenesis and lymphangiogenesis.Oct 03, 2016

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Pubmed Data : J Agric Food Chem. 2016 Oct 4. Epub 2016 Oct 4. PMID: 27700072

Article Published Date : Oct 03, 2016

Study Type : Animal Study

Additional Links

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor D Inhibitor

[+]

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

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Pubmed Data : Br J Pharmacol. 2012 Feb ;165(4):994-1005. PMID: 21827449

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Pubmed Data : J Cardiovasc Pharmacol. 2011 Dec ;58(6):626-32. PMID: 22146406

Article Published Date : Nov 30, 2011

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Myocardial Infarction, Myocardial Ischemia

Pharmacological Actions : Cardioprotective, Vascular Endothelial Growth Factor A Inhibitor

[+]

These results suggested that Korean red ginseng inhibited the development of chronic nonbacterial prostatitis.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutr Cancer. 2014 ;66(8):1394-405. Epub 2014 Oct 20. PMID: 25329001

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Pubmed Data : BMC Cancer. 2009;9:414. Epub 2009 Nov 30. PMID: 19796390

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Berbamine

Diseases : Breast Cancer, Cancer Metastasis

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Corn silk extract may be a promising treatment for inflammatory diseases that involve oxidative stress.May 31, 2012

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Pubmed Data : Inflammation. 2012 Jun ;35(3):822-7. PMID: 21898269

Article Published Date : May 31, 2012

Pubmed Data : J Cell Biochem. 2008 Sep 1 ;105(1):53-60. PMID: 18452159

Article Published Date : Sep 01, 2008

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Comput Math Methods Med. 2022 ;2022:2813142. Epub 2022 Jun 28. PMID: 35799655

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Lung Cancer

Pharmacological Actions : NF-kappaB Inhibitor, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Integrated analysis and finding reveal anti-liver cancer targets and mechanisms of Poria cocos polysaccharides.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Oncol. 2018 Jun ;52(6):2051-2060. Epub 2018 Apr 2. PMID: 29620259

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View the Evidence: 116 Abstracts with Vascular Endothelial Growth Factor A Inhibitor Research

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Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease.Apr 01, 2008

Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.Sep 11, 2019

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

Shenyi Capsule, a traditional chinese medicine formula with ginsenoside Rg3 as its main active ingredient, works synergistically with chemotherapy in the treatment of advanced esophageal cancer.Nov 01, 2009

Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Antiviral and immunomodulatory effects of Pelargonium sidoides DC. root extract EPs® 7630 in SARS-CoV-2-infected human lung cells.Dec 31, 2020

Sesamin inhibits hypoxia-stimulated angiogenesis.Aug 29, 2022

Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.Dec 31, 2019

"Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization."Mar 01, 2010

A compound in Chinese skullcap known as baicalein reduces the inflammatory process in a rodent model of diabetic retinopathyMay 01, 2009

A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits angiogenesis of tumor cells.Dec 01, 2006

A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits breast cancer.Aug 01, 2009

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.Nov 17, 2009

Activation of cannabinoid receptors could be a new therapeutic approach for the treatment of skin tumors.Dec 31, 2002

Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis.Dec 31, 2013

Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade.Jul 24, 2014

Angelica sinensis exerts angiogenic and anti-apoptotic effects against cerebral ischemia-reperfusion injury.Dec 31, 2016

Apigenin is a bioflavonoid that inhibits hypoxia-activated pathways linked to cancer progression in human prostate cancerSep 01, 2008

Berberine protects against chronic cerebral hypoperfusion-induced cognitive impairment and hippocampal damage.Jun 09, 2022

Cannabidiol has a neuroprotective and blood-retinal-preserving effect in experimental diabetes. Jan 01, 2004

Curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition.Jan 31, 2015

Curcumin inhibits ascites tumor growth in mice. May 01, 2005

Curcumin is an in vivo inhibitor of angiogenesis.Jun 01, 1998

Curcumin may be useful as an angiogenic inhibitor in the treatment of corneal diseases that show neovascularization.Jan 01, 2008

Curcumin may have a preventive role in the treatment of diabetic retinopathy. Sep 21, 2007

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.Dec 01, 2009

Curcumin reduces pulmonary tumorigenesis in transgenic mice. Jul 01, 2011

Curcumin treats endometriosis in mice by the HIF signaling pathway.Dec 31, 2021

Dietary oleuropein inhibits tumor angiogenesis and lymphangiogenesis in the B16F10 melanoma allograft model.Mar 30, 2017

DIM is a possible treatment option for inflammation of the intestine and associated angiogenesis and lymphangiogenesis.Oct 03, 2016

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

Epigallocatechin gallate relieves asthmatic symptoms.May 27, 2022

Farnesiferol C, a major compounds isolated from Ferula assafoetida, exerts antiangiogenic and antitumor activity in a human lung cancer allograft model. Jan 26, 2010

Flaxseed and its lignans have potent antiestrogenic effects on estrogen receptor-positive breast cancer and may prove to be beneficial in breast cancer prevention strategies in the future.Feb 01, 2007

Gac seeds enhance gastric ulcer healing.Jun 01, 2010

Genistein aglycone might be an effective alternative therapy for the management of age-related skin changes in postmenopausal women.Jan 31, 2012

Inositol hexaphosphate suppresses hormone-refractory prostate cancer growth. Jan 01, 2004

L-arginine ameliorates hypoxic pulmonary hypertension.Jun 01, 2009

Lycopene inhibits experimental metastasis of human hepatoma in athymic mice. Mar 01, 2008

Methylmercury induces blood brain barrier damage via upregulation of vascular endothelial growth factor in vivo.Jan 01, 2017

Monacolin K, a metabolite of red yeast rice, reduces tumor progression and metastasis of Lewis lung cancer.Sep 23, 2009

Nigella sativa oil and thymoquinone treatment decreased albuminuria in experimental models of the diabetic nephropathy.May 31, 2016

Norcantharidin, a compound found within the traditional Chinese medicine Mylabris, has an anti-angiogenic activity in human gallbladder cancer cells.Mar 14, 2006

Oridonin inhibits VEGF-A-associated angiogenesis and epithelial-mesenchymal transition of breast cancer.Jul 31, 2018

Psoralidin exerts anti-tumor, anti-angiogenic, and immunostimulatory activities in 4T1 tumor-bearing balb/c mice.Sep 08, 2021

Quercetin attenuates cell Survival, inflammation, and angiogenesis in murine T-cell lymphoma.Jan 19, 2017

Quercetin inhibits surgically induced endometriosis in rats.Mar 01, 2009

Red sage contains a compound salvianolic acid B which compares favorably to benazepril in the treatment of chronic myocardial infarction in rats.Sep 01, 2008

Resveratrol alleviates dextran sulfate sodium-induced acute ulcerative colitis.Dec 31, 2020

Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia.Sep 14, 2010

Silibinin suppresses advanced human prostate cancer growth in athymic mice through reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis.Sep 01, 2003

Spica Prunellae may be a potential novel therapeutic agent for the treatment of cancers with constitutive activation of STAT3.Dec 31, 2012

Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis.Jan 31, 2017

Therapeutic potential of fucoidan in myocardial ischemia.Nov 30, 2011

These results suggested that Korean red ginseng inhibited the development of chronic nonbacterial prostatitis.Dec 31, 2018

"Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor."Oct 31, 2008

A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW-480 cells.Sep 06, 2022

A nutrient mixture containing lysine, proline, ascorbic acid, and green tea extract inhibits corneal neovascularization. Oct 01, 2007

An açai polyphenolic extract had antiinflammatory and cytotoxic activities in colon cancer cells and can be effective as natural colon cancer chemopreventive agent.Dec 31, 2013

Andrographolide reduced VEGFA expression in hepatoma cancer cells.Jul 31, 2017

Astragaloside IV exerts anti-tumor effect on nurine colorectal cancer by re-educating tumor-associated macrophage.Oct 22, 2020

Baicalin modulates inflammatory response of macrophages activated by LPS.Sep 29, 2022

Berbamine suppresses growth, migration and invasion of highly-metastatic human breast cancer cells.Jan 01, 2009

Corn silk extract may be a promising treatment for inflammatory diseases that involve oxidative stress.May 31, 2012

Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo.Mar 01, 2010

Curcumin can suppress the growth of prostate cancer cells. Feb 01, 2008

Curcumin has anti-angiogenic properties.May 01, 2006

Curcumin inhibits B-cell lymphoma cells. Dec 20, 2005

Curcumin inhibits hypoxia-induced angiogenesis associated wtih tumor progression.Jun 01, 2006

Curcumin inhibits liver tumor angiogenesis and growth. Jan 01, 2006

Curcumin inhibits pancreatic cancer cell and tumor growth.Aug 13, 2010

Curcumin inhibits the migration and invasion of human and lung cancer cells.Nov 28, 2009

Vascular Endothelial Growth Factor A Inhibitor

View the Evidence:
116 Abstracts with Vascular Endothelial Growth Factor A Inhibitor Research