Vascular Endothelial Growth Factor A Inhibitor

Name	AC	CK
Curcumin	20	28
Arginine	2	12
Enterolactone	2	12
Flaxseed	2	12
Lignans	2	12
Resveratrol	10	12
Chinese Herbal Formula: Shenyi Capsule	1	10
Diosmin	1	10
Green Tea	4	7
Genistein	4	6
Quercetin	4	6
Amurensin G	1	5
Geranium	1	5
Lysine	3	5
Proline	3	5
Vitamin C	3	5
Ginsenosides	3	4
Milk Thistle	2	4
Thymoquinone	3	4
Andrographis	2	3
Berberine	2	3
Chrysin	1	3
Flavonoids	2	3
Inositol Hexaphosphate	2	3
Seaweed: Brown	1	3
Sesamin	1	3
Angelica	1	2
Apigenin	1	2
Asafoetida	1	2
Ashwagandha	1	2
Babchi	1	2
Bacopa	1	2
Cannabidiol	1	2
Cannabinoids	1	2
Carnitine	1	2
Chinese Skullcap	1	2
Diosgenin	1	2
EGCG (Epigallocatechin gallate)	1	2
Emodin	1	2
Enterodiol	1	2
Fucoidan	1	2
Gac	1	2
Ginseng (Korean)	1	2
Hydrogen: Molecular	1	2
Isothiocyanates	1	2
Ligustrazine	1	2
Luteolin	2	2
Lycopene	1	2
Nigella sativa (aka Black Seed)	1	2
Oleuropein	1	2
Oridonin	1	2
Protandim	1	2
Prunella vulgaris	1	2
Red Sage	1	2
Red Yeast Rice	1	2
Silibinin	1	2
Soy	1	2
Traditional Chinese Medicine: Mylabris	1	2
Turmeric	1	2
Acai	1	1
Andrographolide	1	1
Astaxanthin	1	1
Astragaloside	1	1
Avenanthramides	1	1
Beet	1	1
Berbamine	1	1
Beta-Elemene	1	1
Bufalin	1	1
Cannabinoids: Synthetic	1	1
Catechin	1	1
Corn Silk	1	1
Estradiol (E(2))	1	1
Evodiamine	1	1
Fucoxanthin	1	1
Genipin	1	1
Ginkgo biloba	1	1
Grape	1	1
Isoliquiritigenin	1	1
Ketone Bodies	1	1
Lactoferrin	1	1
Melatonin	1	1
NAC (N-acetyl-L-cysteine)	1	1
Oats	1	1
Olive leaf extract	1	1
Picropodophyllin	1	1
Polyphenols	1	1
Poria cocos	1	1
Pterostilbene	1	1
Red Wine Extract	1	1
Rutin	1	1
St. Johns Wort	1	1
Stilbenes	1	1
Tripterygium wilfordii	1	1
Triptolide	1	1
Vitamin E	1	1
Water: Electrolyzed Reduced	1	1

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Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease.Apr 01, 2008

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Pubmed Data : J Thorac Cardiovasc Surg. 2008 Apr;135(4):762-70, 770.e1. Epub 2008 Mar 18. PMID: 18374753

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Substances : Arginine

Diseases : Coronary Artery Disease, Coronary Bypass Surgery

Pharmacological Actions : Vascular Endothelial Growth Factor A Inhibitor

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Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.Sep 11, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 Sep 12 ;24(18). Epub 2019 Sep 12. PMID: 31547271

Article Published Date : Sep 11, 2019

Study Type : Human Study

Additional Links

Substances : Diosmin

Diseases : Chronic Venous Insufficency

Pharmacological Actions : Angiogenesis Inhibitors, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor

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Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Arterioscler Thromb Vasc Biol. 2010 Mar ;30(3):426-35. Epub 2010 Jan 7. PMID: 20056909

Article Published Date : Mar 01, 2010

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Pubmed Data : Mol Cell Biochem. 2005 May;273(1-2):57-67. PMID: 16013440

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Pubmed Data : Biochem Biophys Res Commun. 2007 Sep 21;361(2):528-32. Epub 2007 Jul 23. PMID: 17662242

Article Published Date : Sep 21, 2007

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Vascular Endothelial Growth Factor A Inhibitor

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Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.Dec 01, 2009

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Pubmed Data : Cancer Res. 2009 Dec 1;69(23):8958-66. Epub 2009 Nov 10. PMID: 19903839

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

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Pubmed Data : Br J Pharmacol. 2012 Feb ;165(4):994-1005. PMID: 21827449

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Pubmed Data : Nutr Cancer. 2014 ;66(8):1394-405. Epub 2014 Oct 20. PMID: 25329001

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Pubmed Data : BMC Cancer. 2009;9:414. Epub 2009 Nov 30. PMID: 19796390

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Berbamine

Diseases : Breast Cancer, Cancer Metastasis

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Drug-Plant-Vitamin Synergies

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Corn silk extract may be a promising treatment for inflammatory diseases that involve oxidative stress.May 31, 2012

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Pubmed Data : Inflammation. 2012 Jun ;35(3):822-7. PMID: 21898269

Article Published Date : May 31, 2012

Pubmed Data : J Cell Biochem. 2008 Sep 1 ;105(1):53-60. PMID: 18452159

Article Published Date : Sep 01, 2008

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2017 ;10:4023-4028. Epub 2017 Aug 11. PMID: 28860810

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Glioblastoma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor

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Low dose berberine suppresses cholangiocarcinoma cell progression.Sep 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Red wine extract inhibits VEGF secretion and its signalling pathway in retinal ARPE-19 cells to potentially disrupt AMD.Nov 26, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Oncol. 2018 Jun ;52(6):2051-2060. Epub 2018 Apr 2. PMID: 29620259

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View the Evidence: 127 Abstracts with Vascular Endothelial Growth Factor A Inhibitor Research

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Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease.Apr 01, 2008

Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.Sep 11, 2019

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

Shenyi Capsule, a traditional chinese medicine formula with ginsenoside Rg3 as its main active ingredient, works synergistically with chemotherapy in the treatment of advanced esophageal cancer.Nov 01, 2009

Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Antiviral and immunomodulatory effects of Pelargonium sidoides DC. root extract EPs® 7630 in SARS-CoV-2-infected human lung cells.Dec 31, 2020

Chrysin-induced regression of angiogenesis in models of melanoma.Jun 05, 2023

Sargassum fusiforme polysaccharides inhibit VEGF-A-related angiogenesis and proliferation of lung cancer.Dec 31, 2016

Sesamin inhibits hypoxia-stimulated angiogenesis.Aug 29, 2022

Synergistic effects of photobiomodulation therapy with combined wavelength on diabetic wound healing.Dec 31, 2021

Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.Dec 31, 2019

"Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization."Mar 01, 2010

A compound in Chinese skullcap known as baicalein reduces the inflammatory process in a rodent model of diabetic retinopathyMay 01, 2009

A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits angiogenesis of tumor cells.Dec 01, 2006

A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits breast cancer.Aug 01, 2009

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.Nov 17, 2009

Activation of cannabinoid receptors could be a new therapeutic approach for the treatment of skin tumors.Dec 31, 2002

Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis.Dec 31, 2013

Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade.Jul 24, 2014

Angelica sinensis exerts angiogenic and anti-apoptotic effects against cerebral ischemia-reperfusion injury.Dec 31, 2016

Apigenin is a bioflavonoid that inhibits hypoxia-activated pathways linked to cancer progression in human prostate cancerSep 01, 2008

Berberine protects against chronic cerebral hypoperfusion-induced cognitive impairment and hippocampal damage.Jun 09, 2022

Cannabidiol has a neuroprotective and blood-retinal-preserving effect in experimental diabetes. Jan 01, 2004

Curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition.Jan 31, 2015

Curcumin inhibits ascites tumor growth in mice. May 01, 2005

Curcumin is an in vivo inhibitor of angiogenesis.Jun 01, 1998

Curcumin may be useful as an angiogenic inhibitor in the treatment of corneal diseases that show neovascularization.Jan 01, 2008

Curcumin may have a preventive role in the treatment of diabetic retinopathy. Sep 21, 2007

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.Dec 01, 2009

Curcumin reduces pulmonary tumorigenesis in transgenic mice. Jul 01, 2011

Curcumin treats endometriosis in mice by the HIF signaling pathway.Dec 31, 2021

Dietary oleuropein inhibits tumor angiogenesis and lymphangiogenesis in the B16F10 melanoma allograft model.Mar 30, 2017

DIM is a possible treatment option for inflammation of the intestine and associated angiogenesis and lymphangiogenesis.Oct 03, 2016

Diosgenin may reduce liver lipid synthesis and inflammation and potentiate by down-regulating the mTOR, FASN, HIF-1α, and VEGFA expression.Mar 31, 2023

Effects of laser irradiation (670-nm InGaP and 830-nm GaAlAs) on burn of second-degree in rats.Aug 31, 2014

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

Epigallocatechin gallate relieves asthmatic symptoms.May 27, 2022

Farnesiferol C, a major compounds isolated from Ferula assafoetida, exerts antiangiogenic and antitumor activity in a human lung cancer allograft model. Jan 26, 2010

Flaxseed and its lignans have potent antiestrogenic effects on estrogen receptor-positive breast cancer and may prove to be beneficial in breast cancer prevention strategies in the future.Feb 01, 2007

Gac seeds enhance gastric ulcer healing.Jun 01, 2010

Genistein aglycone might be an effective alternative therapy for the management of age-related skin changes in postmenopausal women.Jan 31, 2012

Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer.Aug 31, 2018

Inositol hexaphosphate suppresses hormone-refractory prostate cancer growth. Jan 01, 2004

L-arginine ameliorates hypoxic pulmonary hypertension.Jun 01, 2009

Lycopene inhibits experimental metastasis of human hepatoma in athymic mice. Mar 01, 2008

Methylmercury induces blood brain barrier damage via upregulation of vascular endothelial growth factor in vivo.Jan 01, 2017

Monacolin K, a metabolite of red yeast rice, reduces tumor progression and metastasis of Lewis lung cancer.Sep 23, 2009

Nigella sativa oil and thymoquinone treatment decreased albuminuria in experimental models of the diabetic nephropathy.May 31, 2016

Norcantharidin, a compound found within the traditional Chinese medicine Mylabris, has an anti-angiogenic activity in human gallbladder cancer cells.Mar 14, 2006

Oridonin inhibits VEGF-A-associated angiogenesis and epithelial-mesenchymal transition of breast cancer.Jul 31, 2018

Psoralidin exerts anti-tumor, anti-angiogenic, and immunostimulatory activities in 4T1 tumor-bearing balb/c mice.Sep 08, 2021

Quercetin attenuates cell Survival, inflammation, and angiogenesis in murine T-cell lymphoma.Jan 19, 2017

Quercetin inhibits surgically induced endometriosis in rats.Mar 01, 2009

Red sage contains a compound salvianolic acid B which compares favorably to benazepril in the treatment of chronic myocardial infarction in rats.Sep 01, 2008

Resveratrol alleviates dextran sulfate sodium-induced acute ulcerative colitis.Dec 31, 2020

Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia.Sep 14, 2010

Silibinin suppresses advanced human prostate cancer growth in athymic mice through reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis.Sep 01, 2003

Spica Prunellae may be a potential novel therapeutic agent for the treatment of cancers with constitutive activation of STAT3.Dec 31, 2012

Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis.Jan 31, 2017

Therapeutic potential of fucoidan in myocardial ischemia.Nov 30, 2011

These results suggested that Korean red ginseng inhibited the development of chronic nonbacterial prostatitis.Dec 31, 2018

This study concluded that genistein prevented endometriosis by performing the antiangiogenic activity and showed a similar function to estradiol.Dec 31, 2023

"Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor."Oct 31, 2008

A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW-480 cells.Sep 06, 2022

A nutrient mixture containing lysine, proline, ascorbic acid, and green tea extract inhibits corneal neovascularization. Oct 01, 2007

An açai polyphenolic extract had antiinflammatory and cytotoxic activities in colon cancer cells and can be effective as natural colon cancer chemopreventive agent.Dec 31, 2013

Andrographolide reduced VEGFA expression in hepatoma cancer cells.Jul 31, 2017

Astragaloside IV exerts anti-tumor effect on nurine colorectal cancer by re-educating tumor-associated macrophage.Oct 22, 2020

Baicalin modulates inflammatory response of macrophages activated by LPS.Sep 29, 2022

Berbamine suppresses growth, migration and invasion of highly-metastatic human breast cancer cells.Jan 01, 2009

Corn silk extract may be a promising treatment for inflammatory diseases that involve oxidative stress.May 31, 2012

Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo.Mar 01, 2010

Vascular Endothelial Growth Factor A Inhibitor

View the Evidence:
127 Abstracts with Vascular Endothelial Growth Factor A Inhibitor Research