Vascular Endothelial Growth Factor Inhibitors

Name	AC	CK
Ginsenosides	22	39
Resveratrol	7	28
Curcumin	14	24
Vitamin D	3	22
Coenzyme Q10	2	21
Flavonoids	14	19
Bilberry	3	13
EGCG (Epigallocatechin gallate)	6	13
Thymoquinone	8	13
Melatonin	6	12
Nigella sativa (aka Black Seed)	2	12
Cannabinoids	2	11
Delta-tetrahydrocannabinol (THC)	1	10
Flaxseed	1	10
Omega-3 Fatty Acids	1	10
Polyphenols	4	10
Tanshinone IIA	10	10
Zataria multiflora	1	10
Anthocyanins	4	7
Apigenin	6	7
Parthenolide	5	7
Vitamin C	5	6
Apple Polyphenols	1	5
Bee Venom	3	5
Berberine	4	5
Black Raspberry	1	5
Ginkgo biloba	3	5
Lactoferrin	4	5
Xanthohumol	4	5
Beta-Elemene	3	4
Chlorella (Algae)	2	4
Crocin	3	4
Fucoidan	4	4
Genistein	3	4
Gingerol	2	4
Hesperidin	2	4
Honokiol	3	4
Paeoniflorin	2	4
Quercetin	3	4
Silibinin	2	4
Sulforaphane	2	4
Tetrahydrocurcumin	2	4
Angelica	2	3
Astragaloside	2	3
Caffeic acid phenethyl ester	2	3
Chlorogenic Acid	3	3
Cinnamon	3	3
Citrus Triterpenoids	1	3
Crocetin	3	3
Delphinidin	2	3
Ferulic acid	1	3
Huaier (Trametes robiniophila murr)	2	3
Licorice	2	3
Lignans	2	3
Luteolin	3	3
Lychee	2	3
Neem	2	3
Nobiletin	2	3
Palmitoylethanolamide	2	3
Peony	2	3
Piceatannol	2	3
Puerarin	3	3
Ursolic Acid	3	3
Acai	1	2
Achiote	1	2
Amla Fruit	1	2
Andrographis	1	2
Arctigenin	1	2
Ashwagandha	1	2
Asiatic Acid	1	2
Astaxanthin	1	2
Astragalus	1	2
Bamboo	1	2
Banana	1	2
Betaine	1	2
Biochanin A	1	2
Black Pepper	1	2
Black Tea	2	2
Blueberry	2	2
Boswellia	1	2
Broccoli Sprouts	1	2
Burdock	1	2
Camel Milk	1	2
Catechin	1	2
Citicoline	1	2
Corn: Purple	1	2
Ellagic Acid	1	2
Emodin	1	2
Eriodictyol	1	2
Formononetin	2	2
Fruit Peel	1	2
Fucoxanthin	1	2
Garcinia dulcis	1	2
Garcinia indica	1	2
Geraniol	1	2
Ginger	1	2
Ginseng (Korean)	2	2
Harmine	2	2
Hydroxytyrosol	1	2
Indigo Naturalis	1	2
Isoflavones	1	2
Ligustrazine	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Liquiritigenin	2	2
Long Pepper	1	2
Lotus	2	2
Lycopene	1	2
MSM (Methylsulfonylmethane)	1	2
Magnolol	1	2
Myricetin	1	2
Nettle	1	2
Olive Oil	1	2
Oridonin	1	2
Orthosiphon	1	2
Palash	1	2
Phlorotannins	2	2
Pine Bark Extract	1	2
Pine Needle	1	2
Pomegranate Peel	2	2
Saccharomyces Boulardii	1	2
Safflower	1	2
Safranal	1	2
Sea buckthorn	1	2
Seaweed	1	2
Shikonin	1	2
Sophora Flavescens	1	2
Soursop	1	2
Spirulina	1	2
St. Johns Wort	1	2
Syrian rue	2	2
Terminalia	1	2
Theaflavins	2	2
Thymol	1	2
Tomato	1	2
Triphala	1	2
Turmeric	2	2
Velvet antler	1	2
Vitamin B-3 (Niacin)	1	2
Vitexins	1	2
Whey	1	2
White Mulberry	1	2
Wogonin	2	2
Andrographolide	1	1
Barberry	1	1
Basil	1	1
Benzyl isothiocyanate	1	1
Betulinic acid	1	1
Cannabidiol	1	1
Cannabis	1	1
Capsaicin	1	1
Carnosic Acid	1	1
Carrot	1	1
Celastrol	1	1
Celery	1	1
Chrysin	1	1
Cinnamaldehyde	1	1
Cucurbitacin B	1	1
Cyanidin 3-glucoside	1	1
D-Limonene	1	1
Dandelion	1	1
Diosgenin	1	1
Echinacea	1	1
Elm tree	1	1
Fisetin	1	1
Frankincense	1	1
Galbanic Acid	1	1
Gallic Acid	1	1
Glycyrrhizin	1	1
Gold (nanoparticles)	1	1
Grape	1	1
Guggul	1	1
Holy Basil	1	1
Homeopathic Medicine: All	1	1
Hydrangea	1	1
Isoliquiritigenin	1	1
Kaempferol	1	1
Mangiferin	1	1
Moringa oleifera	1	1
Mulberry	1	1
Naringenin	1	1
Oak	1	1
Paeonol	1	1
Patchouli	1	1
Persimmon	1	1
Phenethyl isothiocyanate	1	1
Phloretin	1	1
Piperine	1	1
Proanthocyanidins	1	1
Procyanidin B2	1	1
Prunella vulgaris	1	1
Psychedelics:All	1	1
Pterostilbene	1	1
Reishi Mushroom	1	1
Royal Jelly	1	1
Saffron	1	1
Schisandra	1	1
Seaweed: Brown	1	1
Selenium	1	1
Silymarin	1	1
Tannic Acid	1	1
Toona sinensis	1	1
Vitamin E	1	1
Zerumbone	1	1

[+]

CoQ10 supplementation reduced some of the important markers of inflammation and MMPs in patients with breast cancer.May 31, 2021

Click here to read the entire abstract

Pubmed Data : Inflammopharmacology. 2021 Jun ;29(3):579-593. Epub 2021 May 18. PMID: 34008150

Article Published Date : May 31, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Coenzyme Q10

Diseases : Breast Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Environ Sci Pollut Res Int. 2020 Apr 20. Epub 2020 Apr 20. PMID: 32314290

Article Published Date : Apr 19, 2020

Study Type : Human Study

Additional Links

Substances : Zataria multiflora

Diseases : Chemical Weapon Agent Injury: Sulfur Mustard, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with polycystic ovary syndrome.Mar 27, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID: 27468227

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors, Wnt/β-catenin signaling pathway modulation

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Gene Expression Regulation

[+]

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2016 Feb 5 ;245:1-11. Epub 2015 Dec 8. PMID: 26680107

Article Published Date : Feb 04, 2016

Study Type : Animal Study

Additional Links

Substances : Thymol

Diseases : Diabetic Nephropathy, High Fat Diet

Pharmacological Actions : Renoprotective, Vascular Endothelial Growth Factor Inhibitors

[+]

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2013 ;2013:463145. Epub 2013 Oct 3. PMID: 24224164

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Achiote

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26116834

Article Published Date : Jun 07, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Exosomes

[+]

Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cosmet Laser Ther. 2011 Oct ;13(5):237-42. PMID: 21774661

Article Published Date : Sep 30, 2011

Study Type : Animal Study

Additional Links

Diseases : Burns, Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor Inhibitors

[+]

Effect of total glucosides of paeony on imiquimod-induced psoriatic skin lesions.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Indigo naturalis and its component tryptanthrin exert anti-angiogenic effect by arresting cell cycle and inhibiting Akt and FAK signaling in human vascular endothelial cells.Nov 03, 2015

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27059477

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cells. 2023 Mar 3 ;12(5). Epub 2023 Mar 3. PMID: 36899935

Article Published Date : Mar 02, 2023

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Macular Degeneration

Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors

[+]

Melatonin mitigates the progression of chemically induced hepatocellular carcinoma.Sep 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2017 04 ;61(4). Epub 2017 Jan 30. PMID: 27921359

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Xanthohumol

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors

[+]

Morelloflavone is a potential inhibitor of tumor angiogenesis by targeting the Rho GTPase and ERK signaling pathways.Jan 14, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Res. 2009 Jan 15 ;69(2):518-25. PMID: 19147565

Article Published Date : Jan 14, 2009

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Garcinia dulcis

Diseases : Prostate Cancer

Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

[+]

Musa acuminata lectin protein has promising anticancer potential.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2019 ;71(2):285-300. Epub 2018 Dec 29. PMID: 30596280

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Banana

Diseases : Cancers: All, Ehrlich carcinoma

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic, Vascular Endothelial Growth Factor Inhibitors

[+]

Click here to read the entire abstract

Pubmed Data : Exp Parasitol. 2019 Feb ;197:85-92. Epub 2018 Nov 8. PMID: 30414842

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Paeoniflorin

Diseases : Liver Disease, Schistosomiasis

Pharmacological Actions : Anti-Angiogenic, Anti-Fibrotic, Vascular Endothelial Growth Factor Inhibitors

[+]

Palmitoylethanolamide may improve inflammation-driven angiogenesis in colonic mucosa.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Reprod Sci. 2013 Oct ;20(10):1230-6. Epub 2013 Mar 27. PMID: 23536571

Article Published Date : Sep 30, 2013

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Endometriosis

Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors

[+]

Click here to read the entire abstract

Pubmed Data : Sci Rep. 2022 Sep 23 ;12(1):15872. Epub 2022 Sep 23. PMID: 36151457

Article Published Date : Sep 22, 2022

Study Type : Animal Study

Additional Links

Substances : Silibinin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma.Oct 03, 2017

Pubmed Data : Int J Mol Sci. 2016 Dec 9 ;17(12). Epub 2016 Dec 9. PMID: 27941690

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Trop Med. 2017 Apr ;10(4):400-408. Epub 2017 Apr 7. PMID: 28552110

Article Published Date : Mar 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Resveratrol, Thymoquinone

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic, Immunomodulatory, Interferon-gamma (IFN-gamma) inducer, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance Synergy

[+]

Thymoquinone augmented the chemopreventive effect of vitamin D during the initiation phase of colon cancer.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Vis. 2016 ;22:599-609. Epub 2016 Jun 9. PMID: 27293376

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2021 Feb 3 ;26(4). Epub 2021 Feb 3. PMID: 33546250

Article Published Date : Feb 02, 2021

Study Type : In Vitro Study

Additional Links

Substances : Elm tree

Diseases : Cancers: All, Inflammation

Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

[+]

A hydroalcoholic extract of oak acorn shell acts as a potent antiangiogenic agent.Feb 28, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharm Biol. 2013 Mar ;51(3):361-8. Epub 2012 Nov 8. PMID: 23137183

Article Published Date : Feb 28, 2013

Study Type : In Vitro Study

Additional Links

Substances : Oak

Diseases : Cancers: All

Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

[+]

[+]

Anti-metastatic potential of natural triterpenoid cucurbitacin B against cholangiocarcinoma cells.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Integr Cancer Ther. 2022 Jan-Dec;21:15347354221124861. PMID: 36154723

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Cucurbitacin B

Diseases : Cholangiocarcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice.Sep 30, 2008

Click here to read the entire abstract

Pubmed Data : Cancer Biother Radiopharm. 2008 Oct ;23(5):647-53. PMID: 18999937

Article Published Date : Sep 30, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:460. Epub 2020 Apr 8. PMID: 32322211

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Dandelion

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Polysaccharides

[+]

Honokiol: a review of its anticancer potential and mechanisms.Dec 21, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2019 Dec 22 ;12(1). Epub 2019 Dec 22. PMID: 31877856

Article Published Date : Dec 21, 2019

Study Type : Review

Additional Links

Substances : Honokiol

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Chemopreventive, Vascular Endothelial Growth Factor Inhibitors

[+]

Huaier is a potent anti-tumor and immunomodulatory drug, which could inhibit the infiltration of M2-macrophages in breast cancer microenvironment.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 ;6:20049. Epub 2016 Feb 1. PMID: 26831282

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Huaier (Trametes robiniophila murr)

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

[+]

Hydrangenol suppresses VEGF-stimulated angiogenesis.Mar 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Inhibitory effects of pectic polysaccharide isolated from Diospyros kaki leaves on tumor cell angiogenesis.Dec 25, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2016 Jul 21 ;188:111-22. Epub 2016 May 10. PMID: 27178635

Article Published Date : Jul 20, 2016

Study Type : In Vitro Study

Additional Links

Substances : Lotus

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

[+]

Low grade glioma cells appear much more sensitive to genistein.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Cell Oncol (Dordr). 2017 Jul 24. Epub 2017 Jul 24. PMID: 28741069

Article Published Date : Jul 23, 2017

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Exosomes

[+]

Neferine reduces the cisplatin dose requirement in cancer chemotherapy.Feb 17, 2017

Click here to read the entire abstract

Pubmed Data : J Cell Biochem. 2017 Feb 18. Epub 2017 Feb 18. PMID: 28214344

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2016 Jun ;30(6):963-70. Epub 2016 Mar 1. PMID: 26929026

Article Published Date : May 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Palmitoylethanolamide

Diseases : Colon Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Vascular Endothelial Growth Factor Inhibitors

[+]

Parthenolide inhibits angiogenesis in esophageal squamous cell carcinoma through suppression of VEGF.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2016 ;44(4):835-49. Epub 2016 May 24. PMID: 27222069

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2011 ;6(9):e25011. Epub 2011 Sep 15. PMID: 21949833

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Puerarin

Diseases : Endometriosis

Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors

[+]

Regressions of breast carcinoma syngraft following treatment with piperine in combination with thymoquinone.Jul 02, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC.Apr 18, 2024

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2024 Apr 19 ;486:116938. Epub 2024 Apr 19. PMID: 38642809

Article Published Date : Apr 18, 2024

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

[+]

Tannic acid exhibits antiangiogenesis activity in nonsmall-cell lung cancer cells.Jul 11, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : ACS Omega. 2022 Jul 12 ;7(27):23939-23949. Epub 2022 Jun 28. PMID: 35847334

Article Published Date : Jul 11, 2022

Study Type : In Vitro Study

Additional Links

Substances : Tannic Acid

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

[+]

Tanshinone IIA can inhibit the expression of COX-2 and activate the Wnt/β-catenin signalling pathway in colon cancer cells.Aug 31, 2018

Click here to read the entire abstract

Pubmed Data : J BUON. 2018 Sep-Oct;23(5):1337-1342. PMID: 30570856

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Colon Cancer

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor Inhibitors, Wnt/β-catenin signaling pathway modulation

Vascular Endothelial Growth Factor Inhibitors jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 335 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research

Limited to Members Only

Currently Available Sorting Options

CoQ10 supplementation reduced some of the important markers of inflammation and MMPs in patients with breast cancer.May 31, 2021

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.Dec 31, 2014

Local ice cryotherapy had beneficial effects in human non-septic knee arthritis.Jul 29, 2019

Powdered Nigella sativa has potent beneficial effects in improving thyroid status and anthropometric variables.Nov 15, 2016

Resveratrol lowers VEGF and TNF-α 2 expression in endometriosis women.Jan 31, 2021

Resveratrol may improve some outcomes of PCOS patients.Jul 20, 2019

The influences of vitamin D and omega-3 co-supplementation on clinical, metabolic and genetic parameters in women with polycystic ovary syndrome.Sep 30, 2018

These findings support the potential role of flaxseed in treating dyslipidaemia.Jul 12, 2022

Two months' of treatment with Z. multiflora improved cytokine levels, respiratory symptom, and FEV1 values in sulfur mustard-exposed patients.Apr 19, 2020

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with polycystic ovary syndrome.Mar 27, 2017

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

Melatonin has anti-angiogenic effects at different steps of the angiogenic process in SH-SY5Y neuroblastoma cells.Feb 13, 2017

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression.Sep 30, 2013

Ferulic acid nanocapsules as a promising treatment modality for colorectal cancer.May 31, 2022

In vivo and in vitro analysis of low level light therapy: a useful therapeutic approach for sensitive skin.Oct 31, 2013

Limonin inhibits angiogenesis and metastasis of human breast cancer cells.Oct 31, 2020

5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.Dec 31, 2015

6-gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer. Jun 04, 2020

A ashwagandha water extract suppressed the tumor growth of glioma cells.Jul 25, 2015

A Huaier polysaccharide restrains hepatocellular carcinoma growth and metastasis.Mar 31, 2015

A purple corn extract may be a potent therapeutic agent targeting abnormal angiogenesis in diabetic nephropathy leading to kidney failure.Dec 31, 2012

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Administration of thymol afforded remarkable protection against high fat diet induced diabetic nephropathy.Feb 04, 2016

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

An immune-modulating diet in combination with chemotherapy prevented cancer cachexia without suppressing chemotherapeutic efficacy.Jul 01, 2015

Andrographolide ameliorates diabetic retinopathy by inhibiting retinal angiogenesis and inflammation.Mar 31, 2015

Annona muricata leaves showed an ameliorative effect in a murine model of breast cancer.Mar 09, 2022

Anti-angiogenic effect of shikonin in rheumatoid arthritis.May 31, 2020

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.Nov 11, 2019

Arctigenin prevents retinal edema in a murine retinal vein occlusion model. Dec 31, 2022

Arctiin inhibits inflammation, fibrosis, and tumor cell migration in rats with Ehrlich solid carcinoma.Aug 31, 2023

Astaxanthin inhibits homocysteine‑induced endothelial cell dysfunction.Apr 11, 2019

Astragaloside IV and curcumin alone and in combination significantly reduced mean tumor weight compared to vehicle control.Dec 31, 2016

Bamboo leaf extract could improve wound closure by 28 % at 12 hours and 54 % at 24 hours in mice.Nov 30, 2014

Berberine improves insulin-induced diabetic retinopathy in type I and II diabetes.Dec 31, 2020

Betaine may potentially be used to delay the onset of complications associated with diabetic retinopathy via inhibition of retinal neovascularization in patients with diabetes.Jul 31, 2015

Biochanin A regulates the growth and migration of NSCLC through suppressing the VEGF/VEGFR2 signaling pathway.Jul 22, 2018

Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model). Jan 01, 2011

Caffeic acid phenethyl ester mitigates infertility: A crucial role of metalloproteinase and angiogenic factor in cadmium-induced testicular damage.Nov 16, 2021

Camel milk inhibits inflammatory angiogenesis via downregulation of proangiogenic and proinflammatory cytokines in mice.Jun 30, 2014

Chebulinic acid is a safe and effective antiangiogenic agent in collagen-induced arthritis in mice.Jan 22, 2020

Crocin and Metformin suppress metastatic breast cancer progression.Apr 29, 2021

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.Sep 07, 2010

Curcumin inhibits lymphangiogenesis in vitro and in vivo, which could contribute to the antimetastatic effects of curcumin.Aug 26, 2015

Curcumin not only inhibits tumor angiogenesis, but also suppresses the production of VEGF in response to hypoxia.Aug 13, 2015

Curcumin treated animals had a significant reduction in tumor growth as measured by the decrease in size of the subcutaneous xenografts compared to untreated animals.Jun 07, 2015

Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.Jul 04, 2015

Didymin by suppressing NF-κB activation prevents VEGF-induced angiogenesis in vitro and in vivo.Dec 31, 2018

Dietary administration of garcinol effectively reduced the tumor size and incidence in the mouse colon.Aug 31, 2014

Effect of electroacupuncture intervention on angiogenesis in psoriasis.Jun 24, 2024

Effect of low-level laser therapy (660 nm) on the healing of second-degree skin burns.Sep 30, 2011

Effect of total glucosides of paeony on imiquimod-induced psoriatic skin lesions.Dec 31, 2020

EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.May 31, 2015

Electroacupuncture ameliorates inflammatory response of mice with acute myocardial ischemia.Oct 24, 2022

Ellagic acid exerted protective effects against carbon tetrachloride-induced cirrhosis through the inhibition of ROS formation and angiogenesis.Sep 30, 2017

Emodin ameliorates acute radiation proctitis.May 09, 2024

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

Evaluation of antiangiogenic and antiproliferative potential of the organic extract of green algae Chlorella pyrenoidosa.Dec 31, 2012

Extra virgin olive oil modulates vasodilator enzyme level by repairing angiogenesis function in rat model of preeclampsia.Feb 29, 2020

Galangin inhibits epithelial-mesenchymal transition and angiogenesis by downregulating CD44 in glioma.Dec 31, 2018

Genistein mediated upregulation of CHOP impeded C/EBPβ interaction with the IL-6 promoter, thus disturbing the angiogenic microenvironment which inhibited tumor proliferation.May 31, 2015

Geraniol is an attractive candidate for the anti-angiogenic treatment of tumors.Dec 31, 2014

Ginkgo biloba exocarp extracts played the effects of anti-tumor and anti-metastatic depending upon the inhibition of tumor angiogenesis.Nov 03, 2016

Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.Jun 17, 2016

Ginsenoside Rg3 significantly inhibited growth and angiogenesis of ovarian cancer when used alone or combined with cyclophosphamide.Apr 04, 2007

Vascular Endothelial Growth Factor Inhibitors

View the Evidence:
335 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research