Vasodilator Agents

Name	AC	CK
Arginine	9	68
Cannabidiol	5	38
Resveratrol	12	37
Polyphenols	5	35
Ginkgo biloba	4	24
Flavonoids	4	23
Chocolate	3	21
Beet	2	20
Black Tea	2	20
Citrulline	2	20
Homeopathic Medicine: Ambra grisea	2	20
Homeopathic Medicine: Anamirta cocculus	2	20
Homeopathic Medicine: Conium maculatum	2	20
Homeopathic Medicine: Petroleum rectificatum	2	20
Puerarin	5	16
Red Wine Extract	3	13
Vitamin C	3	13
Alpha-Lipoic Acid	2	12
Genistein	2	12
Omega-3 Fatty Acids	2	12
Tea	2	12
Vinegar	2	11
Acetyl-l-carnitine	1	10
Alcohol	1	10
B-complex	1	10
Beer	1	10
Black Currant	1	10
Capsaicin	1	10
Carnitine: propionyl-L-carnitine	1	10
Cocoa	1	10
Green Tea	1	10
Homeopathic Medicine: All	1	10
Melatonin	1	10
NAC (N-acetyl-L-cysteine)	1	10
Pomegranate	1	10
Selenium	1	10
Vitamin B-12	1	10
Watermelon	1	10
Whey	1	10
Hibiscus sabdariffa	5	9
Anthocyanins	2	7
Curcumin	3	6
Turmeric	4	6
DHA (Docosahexaenoic Acid)	1	5
Lotus	3	5
Arugula	2	4
Ferulic acid	2	4
Ginsenosides	2	4
Olive leaf extract	2	4
Phlorotannins	2	4
Safranal	2	4
Schisandra	2	4
Stilbenes	2	4
Allicin	2	3
Cannabinoids	2	3
Chrysin	1	3
Crocetin	2	3
Grape	2	3
Hawthorn	3	3
Hibiscus rosa-sinensis	1	3
Isoflavones	2	3
Magnesium	2	3
Nobiletin	2	3
Olive Oil	2	3
Rosemary	2	3
Seaweed: Brown	2	3
Syrian rue	2	3
18β-Glycyrrhetinic Acid	1	2
Andrographis	1	2
Apple Polyphenols	1	2
Apples	1	2
Apricot	1	2
Astragaloside	1	2
Astragalus	1	2
Baccharis trimera	1	2
Berries: All	1	2
Betaine	1	2
Betulinic acid	1	2
Blueberry	1	2
Cannabis	1	2
Catechin	1	2
Celastrol	1	2
Celery	1	2
Chrysanthemum Morifolium	1	2
Coenzyme Q10	1	2
Curcuminoids	2	2
DHEA (Dehydroepiandrosterone)	1	2
Dates	1	2
EGCG (Epigallocatechin gallate)	1	2
Echinacea	1	2
Ellagic Acid	1	2
Formononetin	1	2
Garlic	1	2
Geraniol	1	2
Geum japonicum	1	2
Ginger	1	2
Gingerol	1	2
Ginseng (Siberian)	1	2
Guava	1	2
Gynura Procumbens	1	2
Hesperidin	1	2
Honeydew (melon)	1	2
Isothiocyanates	1	2
Ligustrazine	1	2
Mangosteen	1	2
Marjoram	1	2
Moringa oleifera	1	2
Mululuza	1	2
Nettle	1	2
Nigella sativa (aka Black Seed)	1	2
Noni	1	2
Orthosiphon	1	2
Paeonol	1	2
Passion fruit	1	2
Peony	1	2
Phellinus Linteus	1	2
Quercetin	1	2
Red Sage	1	2
Rose	1	2
Royal Jelly	1	2
Silibinin	1	2
Soy Protein	1	2
Tannic Acid	1	2
Tauroursodeoxycholic acid	1	2
Thyme	1	2
Thymoquinone	1	2
Tribulus	1	2
Vitamin D	1	2
White Mulberry	1	2
Apigenin	1	1
Artichoke	1	1
Babchi	1	1
Bee Propolis	1	1
Biochanin A	1	1
Caffeic Acid	1	1
Carvacrol	1	1
Coriandrum sativum	1	1
Crocin	1	1
Demethoxycurcumin	1	1
Gastrodin	1	1
Honokiol	1	1
Kaempferol	1	1
Lime: Key	1	1
Luteolin	1	1
Oleuropein	1	1
Olive	1	1
Perillaldehyde	1	1
Piceatannol	1	1
Saffron	1	1
Strawberry	1	1
Tansy	1	1
Ume (Japanese apricot)	1	1

[+]

Endothelial function can be significantly improved in healthy adults in the initial 2 hours after intake of grape polyphenols.Dec 31, 2012

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Pubmed Data : Microbiol Immunol. 1997;41(12):1005-9. PMID: 15750375

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Dark chocolate improves coronary vasomotion and reduces platelet reactivity.Nov 20, 2007

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Pubmed Data : Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID: 17984375

Article Published Date : Nov 20, 2007

Study Type : Human Study

Additional Links

Substances : Flavonoids

Diseases : Blood Platelet Disorders, Clotting, Coronary Artery Disease, Endothelial Dysfunction

Pharmacological Actions : Anti-Platelet, Vasodilator Agents

[+]

Dietary supplementation with whey protein improves systemic microvascular function in heart failure patients.Dec 31, 2020

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Pubmed Data : J Hypertens. 2016 Jul ;34(7):1298-308. PMID: 27088635

Article Published Date : Jun 30, 2016

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Memory Disorders: Sleep Deprivation Induced

Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents

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Folic acid and vitamin B(12) supplementation improves vascular endothelial function in patients with coronary heart disease. Nov 14, 2000

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Pubmed Data : Circulation. 2000 Nov 14;102(20):2479-83. PMID: 11076820

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Pubmed Data : Int J Clin Pharm. 2018 Oct ;40(5):1335-1341. Epub 2018 Jun 1. PMID: 29855986

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Pubmed Data : Nutrients. 2022 Dec 23 ;15(1). Epub 2022 Dec 23. PMID: 36615732

Article Published Date : Dec 22, 2022

Study Type : Human Study

Additional Links

Substances : Citrulline

Diseases : Hypertension

Therapeutic Actions : Exercise: Resistance Training

Pharmacological Actions : Vasodilator Agents

[+]

LLLT significantly increases the perfusion of the skin.Dec 31, 2015

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Pubmed Data : Dev Period Med. 2016 ;20(1):40-6. PMID: 27416624

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Vasodilator Agents

[+]

Long chain omega-3 fatty acid supplementation has the potential to enhance blood flow in the brain in response to both hypercapnic and cognitive stimuli.Oct 01, 2018

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Pubmed Data : Nutrients. 2018 Oct 2 ;10(10). Epub 2018 Oct 2. PMID: 30279397

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Pubmed Data : Br J Clin Pharmacol. 1998 Nov;46(5):489-97. PMID: 9833603

Article Published Date : Nov 01, 1998

Study Type : Human Study

Additional Links

Substances : Arginine

Diseases : Endothelial Dysfunction, Hypertension

Pharmacological Actions : Vasodilator Agents

[+]

Pomegranate extract supplementation enhanced vessel diameter and blood flow, suggesting possible exercise performance enhancement.Mar 31, 2017

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Pubmed Data : Eur J Sport Sci. 2017 Apr ;17(3):317-325. Epub 2016 Sep 20. PMID: 27644475

Article Published Date : Mar 31, 2017

Pubmed Data : Eur Heart J. 2012 Jul ;33(13):1589-97. Epub 2012 Jan 11. PMID: 22240497

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Coronary Artery Disease, Endothelial Dysfunction, Hypertension, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Vasodilator Agents

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Pubmed Data : Cardiovasc Hematol Disord Drug Targets. 2022 03 29. Epub 2022 Mar 29. PMID: 35352670

Article Published Date : Jan 28, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Hibiscus rosa-sinensis

Diseases : Hypertension

Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Vasodilator Agents

[+]

Effects of near-infrared low-level laser irradiation on microcirculation. Dec 31, 1999

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Pubmed Data : Lasers Surg Med. 2000 ;27(5):427-37. PMID: 11126437

Article Published Date : Dec 31, 1999

Study Type : Animal Study, In Vitro Study

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Therapeutic Actions : Infrared Light, Photobiomodulation

Pharmacological Actions : Vasodilator Agents

[+]

A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals.Apr 01, 2007

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Pubmed Data : J Pharmacol Exp Ther. 2007 Apr;321(1):249-56. Epub 2007 Jan 26. PMID: 19494825

Article Published Date : Apr 01, 2007

Study Type : Animal Study

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Pharmacological Actions : Vasodilator Agents

[+]

Acanthopanax senticosus induces Vasorelaxation via endothelial nitric oxide-dependent and -independent pathways.Aug 31, 2019

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Pubmed Data : Planta Med. 2019 Sep ;85(13):1080-1087. Epub 2019 Jul 23. PMID: 31342475

Additional Keywords : Plant Extracts, Proanthocyanidins

[+]

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Pubmed Data : Vascul Pharmacol. 2007 Apr;46(4):278-85. Epub 2006 Nov 10. PMID: 17196887

Article Published Date : Apr 01, 2007

Study Type : Animal Study

Additional Links

Substances : Astragalus

Diseases : Endothelial Damage, Endothelial Dysfunction, High Homocysteine

Pharmacological Actions : Antioxidants, Cardioprotective, Vasodilator Agents

Additional Keywords : Plant Extracts

[+]

Consuming marjoram may have an antihypertensive effect.Jan 10, 2019

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Pubmed Data : Plant Foods Hum Nutr. 2021 Sep 28. Epub 2021 Sep 28. PMID: 34581915

Article Published Date : Sep 27, 2021

Study Type : Animal Study

Additional Links

Substances : Passion fruit

Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 1, Hypertension

Pharmacological Actions : Hypoglycemic Agents, Vasodilator Agents

[+]

In vivo characterization of a red light-activated vasodilation.Dec 31, 2021

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Pubmed Data : J Neurotrauma. 2007 Dec;24(12):1855-62. PMID: 18159997

Article Published Date : Dec 01, 2007

Study Type : Animal Study

Additional Links

Substances : Arginine

Diseases : Spinal Cord Injuries

Pharmacological Actions : Nitric Oxide Enhancer, Vasodilator Agents

[+]

Long-term effect of phytoestrogens from Curcuma comosa Roxb. on vascular relaxation in ovariectomized rats.Jan 24, 2012

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Pubmed Data : J Agric Food Chem. 2012 Jan 25 ;60(3):758-64. Epub 2012 Jan 12. PMID: 22225491

Pubmed Data : Lasers Med Sci. 2022 Mar ;37(2):1209-1216. Epub 2021 Jul 27. PMID: 34313892

Article Published Date : Feb 28, 2022

Study Type : Animal Study

Additional Links

Therapeutic Actions : Light Therapy: Red Colored, Photobiomodulation

Pharmacological Actions : Vasodilator Agents

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Pubmed Data : J Med Food. 2012 Feb ;15(2):190-9. PMID: 22273152

Article Published Date : Feb 01, 2012

Study Type : Animal Study

Additional Links

Diseases : Hypercholesterolemia

Pharmacological Actions : Hypolipidemic, Vasodilator Agents

[+]

Vasodilatory effect of Phellinus linteus extract in rat mesenteric arteries.Jul 09, 2020

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Pubmed Data : Planta Med. 2020 May ;86(7):496-504. Epub 2020 Mar 27. PMID: 32219782

Article Published Date : Apr 30, 2020

Study Type : Animal Study

Additional Links

Substances : Lotus

Diseases : Endothelial Dysfunction, Hypertension

Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents

[+]

Vasorelaxant effect of diterpenoid lactones from Andrographis paniculata chloroform extract on rat aortic rings.Jun 30, 2010

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Carvacrol protects against diabetes-induced hypercontractility in the aorta through activation of the PI3K/Akt pathway.Apr 30, 2020

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Pubmed Data : Molecules. 2015 ;20(9):17570-84. Epub 2015 Sep 22. PMID: 26402666

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Pubmed Data : Med Clin (Barc). 2003 Feb 8;120(4):128-31. PMID: 12605836

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Pubmed Data : BMC Cancer. 2010;10:445. Epub 2010 Aug 20. PMID: 20723265

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Pubmed Data : J Ethnopharmacol. 2008 Oct 30;120(1):98-102. Epub 2008 Aug 7. PMID: 18760343

Article Published Date : Oct 30, 2008

Study Type : In Vitro Study

Additional Links

Substances : Tansy

Diseases : Endothelial Dysfunction, Hypertension

Pharmacological Actions : Hypotensive, Vasodilator Agents

Additional Keywords : Plant Extracts, Science Confirms Tradition

[+]

The cardiovascular therapeutic potential of propolis.Jan 03, 2021

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Pubmed Data : Cardiol Rev. 2018 Mar/Apr;26(2):93-98. PMID: 29419562

Article Published Date : Dec 31, 2017

Study Type : Review

Additional Links

Diseases : Heart Failure

Therapeutic Actions : Acupuncture

Pharmacological Actions : Cardioprotective, Vasodilator Agents

Additional Keywords : Acupuncture, Cardioprotective, Heart Failure, Vasodilator Agents

[+]

This review describes the cardiovascular effects of chocolate.Dec 29, 2018

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Pubmed Data : Mol Nutr Food Res. 2016 Aug ;60(8):1837-49. Epub 2016 Jun 27. PMID: 27213723

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View the Evidence: 228 Abstracts with Vasodilator Agents Research

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Endothelial function can be significantly improved in healthy adults in the initial 2 hours after intake of grape polyphenols.Dec 31, 2012

Short-term oral l-arginine is effective at improving the fasting vascular endothelial function when the baseline fasting flow-mediated dilation is low.Jan 01, 2009

This meta-analysis and systematic review has highlighted the haemodynamic effects of CBD.Dec 31, 2016

Acute vascular benefits of Finnish sauna bathing in patients with stable coronary artery disease.Jun 28, 2020

A combination of homeopathic remedies (Vertigoheel) is as effective a ginko biloba for treating artherosclerosis-related vertigoJan 01, 1997

A homeopathic combination (Vertigoheel) reduced the frequency, duration, and intensity of vertigo attacks and compared favorably to the drug betahistine hydrochloride. Aug 01, 1998

Abnormalities in arterial function and LDL oxidation may persist for at least 2 weeks after a slight inflammatory reaction induced by influenza vaccination.Jan 01, 2007

Acute ingestion of dietary nitrate increases muscle blood flow via local vasodilation during handgrip exercise in young adults.Dec 31, 2017

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure.Jul 29, 2010

Alpha-Lipoic acid and acetyl-L-carnitine appear to improve vascular function and blood pressure in patients with coronary artery disease. Apr 01, 2007

Beer, vodka and especially red wine prevent oxygen-induced oxidative stress associated with arterial stiffness.Jul 12, 2011

Black tea in moderation improved FMD under fasted conditions and preserved FMD under postprandial conditions in hypertensive patients.Nov 15, 2016

Capsaicin treatment in neuropathic pain: axon reflex vasodilatation after four weeks correlates with pain reduction.Jul 19, 2022

Cocoa flavanol consumption facilitates vasodilation and attenuates exercise-induced increases in blood pressure. May 01, 2010

Cocoa flavanol consumption improves lower extremity endothelial function.Oct 16, 2022

Consumption of nutritionally enriched hen eggs enhances endothelium-dependent vasodilation.Mar 24, 2023

Dark chocolate improves coronary vasomotion and reduces platelet reactivity.Nov 20, 2007

Dietary supplementation with whey protein improves systemic microvascular function in heart failure patients.Dec 31, 2020

Effect of whole-body vibration training on transcutaneous oxygen levels of the foot in patients with type 2 diabetes.May 31, 2022

Effects of acute arginine supplementation on neuroendocrine, metabolic, cardiovascular, and mood outcomes in younger men.Aug 31, 2022

Effects of blackcurrant extract on arterial functions in older adults.Oct 01, 2020

Flavanol-rich chocolate counteracted vascular impairment after sleep deprivation and restored working memory performance.Jun 30, 2016

Folic acid and vitamin B(12) supplementation improves vascular endothelial function in patients with coronary heart disease. Nov 14, 2000

Folic acid supplementation significantly improved endothelial dysfunction in patients with coronary atherosclerosis.Sep 01, 2000

Gazpacho soup consumption significantly increases plasma concentrations of vitamin C and significantly decreases 8-epi-PGF2alpha, PGE2 and MCP-1 concentrations in healthy humansFeb 28, 2006

Genistein and puerarin could inhibit the pathway of NF-kappaB and TNF-alpha in asthma patients.Jan 31, 2010

Ginkgo biloba extract EGb 761 versus pentoxifylline in chronic tinnitus.Sep 30, 2018

Hyperbaric oxygen therapy has therapeutic value in idiopathic sudden sensorineural hearing loss. May 01, 2008

Immediate effect of slow pace Bhastrika Pranayama on blood pressure and heart rate. Feb 28, 2009

Immediate effects of monochromatic infrared energy on microcirculation in healthy subjects.Mar 31, 2012

In patients with cirrhosis, dark chocolate blunted the postprandial increase in hepatic venous pressure gradient by improving flow-mediated hepatic vasorelaxation and ameliorated systemic hypotension.Jul 17, 2012

L-arginine protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease.May 01, 2009

L-arginine supplementation improves endothelial dysfunction in MELAS patients.Jun 13, 2006

L-citrulline supplementation improved leg endothelial function in hypertensive postmenopausal women.Dec 22, 2022

LLLT significantly increases the perfusion of the skin.Dec 31, 2015

Long chain omega-3 fatty acid supplementation has the potential to enhance blood flow in the brain in response to both hypercapnic and cognitive stimuli.Oct 01, 2018

Long-term effects of an exercise and Mediterranean diet intervention in the vascular function of an older, healthy population.Aug 31, 2014

PBM induces arteriolar vasodilatation that results in both immediate and long-lasting increased capillary flow and tissue perfusion in healthy individuals.Oct 31, 2020

Pharmokinetics-Pharmodynamics: L-arginine-induced vasodilation in healthy humans.Nov 01, 1998

Pomegranate extract supplementation enhanced vessel diameter and blood flow, suggesting possible exercise performance enhancement.Mar 31, 2017

Pretreatment with an antioxidant regimen increased vasoconstriction. Nov 23, 2015

Propionyl-L-carnitine improves arterial dilatation via NOX2 inhibition in patients with peripheral artery disease. Feb 13, 2012

Pycnogenol improves endothelial function in patients with coronary artery disease by reducing oxidative stress.Jun 30, 2012

Resveratrol may positively modulate cerebral blood flow variables.Jun 01, 2010

Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease.Jul 10, 2001

Systemic effects of low-intensity laser irradiation on skin microcirculation in patients with diabetic microangiopathy.Aug 31, 2002

The effects of L-citrulline and glutathione on endurance performance.Nov 30, 2023

The influence of oral cannabidiol on 24-h ambulatory blood pressure and arterial stiffness in untreated hypertension.Jul 31, 2023

The results showed that dark chocolate consumption for 15 days improved the elastic properties of the LAEI in PLHIV.Jun 20, 2017

This is the first evidence of durable BP reduction with dietary nitrate supplementation with beetroot juice in hypertensive patients.Jan 31, 2015

This study hypothesized that the greater preservation of neurocognitive functions in the morning patients was associated with elevated melatonin levels.May 24, 2015

Vinegar intake enhances flow-mediated vasodilatation via upregulation of endothelial nitric oxide synthase activity.Dec 31, 2009

Wild watermelon-extracted juice ingestion reduces peripheral arterial stiffness with an increase in nitric oxide production.Dec 06, 2022

Anthocyanins inhibit the angiotensin-converting enzyme and xanthine oxidase, decrease low density lipoprotein, and increase nitric oxide.Feb 25, 2020

Cannabidiol causes vasorelaxation of the human mesenteric artery.Aug 31, 2015

These findings indicate that DHA activates PASMC KCa channels leading to vasorelaxation in pulmonary hypertension.Aug 17, 2016

Antihypertensive and vasorelaxant effects of Hibiscus rosa-sinensis.Jan 28, 2022

Effects of near-infrared low-level laser irradiation on microcirculation. Dec 31, 1999

Evaluation of vasodilatory effect and antihypertensive effect of chrysin through in vitro and sub-chronic in vivo study.Dec 31, 2022

Cucurbitacins extracted from Cucumis melo L. (CuEC) exert a hypotensive effect via regulating vascular tone.Dec 31, 2018

Echinacoside prevents hypoxic pulmonary hypertension by regulating the pulmonary artery function Nov 30, 2020

Vasorelaxant effect of Moroccan Cannabis sativa threshing residues on rat mesenteric arterial bed is endothelium and muscarinic receptors dependent.Dec 31, 2022

6-gingerol ameliorates enhanced vascular contraction in diabetic aortae.Dec 31, 2014

A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals.Apr 01, 2007

Acanthopanax senticosus induces Vasorelaxation via endothelial nitric oxide-dependent and -independent pathways.Aug 31, 2019

Aerobic exercise improves BKCa channel-mediated vasodilation.Dec 01, 2023

Aerobic training may be more beneficial for limiting the pathogenesis of vascular disease in type 1 diabetes mellitus than merely intensive insulin therapy.Dec 10, 2018

Alpha-lipoic acid improves endothelial dysfunction in high-fat diet-fed obese mice.Dec 31, 2018

Anthocyanin content in Hibiscus sabdariffa and their antiplatelet and vasorelaxant properties.Apr 28, 2023

Apple leaves contain compounds which may have therapeutic value against advanced glycation end-productions and vasoconstriction. Dec 18, 2009

Apple polyphenol relieves hypoxia-induced pulmonary arterial hypertension.Oct 31, 2018

Aqueous fraction from Hibiscus sabdariffa relaxes mesenteric arteries of normotensive and hypertensive rats.Jun 14, 2020

Vasodilator Agents

View the Evidence:
228 Abstracts with Vasodilator Agents Research