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Found 18 results for "Magnesium"
Articles (6)
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Dec 23, 2012
Magnesium, The missing link
magnesium from their diet, but sometimes magnesium supplements are needed if magnesium levels are too low. Dietary
drgrantwellness
3 min
Jan 07, 2025
Why 80% of Us Are Deficient In Magnesium
magnesium is stored in the blood Most doctors and laboratories don't even include magnesium
drsircus
12 min
Jun 05, 2014
Magnesium Supplements Improve Metabolic Syndrome
magnesium is particularly important for regulating blood sugar and the metabolism. In fact, magnesium deficiency
mmking
3 min
Jul 23, 2020
Magnesium-Rich Foods and Why You Need Them
magnesium in your diet that is preventing you from reaping important health benefits Magnesium (Mg) is considered
DianeFulton
7 min
Apr 07, 2014
Magnesium Lowers Colorectal Cancer Risk
magnesium. Low levels can have deadly effects Epidemiologic studies have suggested that low magnesium may be associated
GMI Research Group
2 minAbstracts (6)
View allpH/ROS-responsive magnesium scaffold functionalized via hydrazone bonds for localized postoperative bone tumor therapy.
Surgery remains the primary treatment strategy for bone tumors such as osteosarcoma; however, patients typically require postoperative radiotherapy and/or chemotherapy to prevent recurrence and metastasis. The implantation of scaffolds to restore bone mechanics is a routine surgical measure. Scaffold systems capable of localized drug release hold great clinical potential, as they can minimize systemic side effects associated with chemotherapy. In this work, we designed a pH/ROS-responsive magnesium scaffold functionalized via hydrazone bonds using micro-arc oxidation technology for controlled release of doxorubicin. Compared with simple physical adsorption, this chemical adsorption strategy markedly enhanced drug loading efficiency (508.4 ng vs. 793.5 ng). Under physiological conditions (pH 7.4), the scaffold released only 2.43 % of doxorubicin over 12 days, whereas in the tumor-mimicking acidic environment (pH 6.2), release reached 84.82 %. In contrast, scaffolds with simple adsorption released 27.68 % and 83 % under the same respective conditions. In vivo studies demonstrated that the intelligent scaffold did not impair wound healing but significantly inhibited osteosarcoma growth (87.67 %). These findings indicate that this responsive scaffold system provides a promising approach for localized postoperative bone tumor therapy with reduced systemic toxicity.
Ding Y, Fen X, Chen S, Zhang Y, Pang Q, Colloids and surfaces. B, Biointerfaces
Elevated Serum Magnesium Levels May Delay the Loss of Residual Renal Function among Patients Receiving Peritoneal Dialysis: A Prospective Study.
The association between serum magnesium and residual renal function (RRF) among peritoneal dialysis (PD) patients remains unclear. The present study examined the relationships between serum magnesium and the risk of anuria in patients receiving continuous ambulatory peritoneal dialysis (CAPD). This prospective cohort study included 261 PD patients in China. All participants received CAPD for more than 3 months between 2012 and December 2022. Loss of RRF (anuria) was characterized by a 24-h urine output below 100 ml. Cox proportional hazard regression models and competing risk models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of anuria across different serum magnesium levels. During the median follow-up of 21.3 (15.0-32.4) months, 130 individuals progressed to anuria. The mean concentration of serum magnesium was 0.9 ± 0.15 mmol/L. After multivariate adjustment, the association of serum magnesium with the risk of anuria was not significant in the entire study population. However, for PD patients with better preservation of RRF, the risk of anuria decreases significantly as serum magnesium increases (HR for per standard deviation increment 0.53, 95% CI 0.32-0.88). The protective effect of increased serum magnesium concentrations on RRF was more pronounced among PD patients with lower triglyceride glucose (TyG) index at baseline compared to those with higher TyG index (p for interaction = 0.03). Our results indicated that higher serum magnesium predicts better renal prognosis for PD patients with better preservation of RRF. Levels of TyG index may modulate the relationship.
Zhao J, Lin X, Wang J, Guo X, Peng F, Zuo X, Tian C, Ying C, Biological trace element research
Association of Serum Magnesium and Calcium Levels in Patients with and without Diastolic Notch in Uterine Artery Doppler Ultrasonography Imaging in the Second Trimester.
BACKGROUND Magnesium and calcium are essential minerals for both maternal and fetal health during pregnancy, with their balance potentially influencing uterine artery function. This study explores the connection between serum magnesium and calcium levels and the presence of a diastolic notch in uterine artery Doppler ultrasonography during the second trimester, a marker that could have significant clinical implications for pregnancy outcomes. MATERIAL AND METHODS In this prospective study, conducted from July 31, 2022, to February 28, 2023, we assessed 60 primigravida women between 18 and 24 weeks of gestation. We measured serum magnesium and calcium levels and analyzed their relationship with diastolic notch presence in uterine artery Doppler ultrasonography, a potential indicator of placental vascular resistance. RESULTS Participants had an average age of 25.7±3.67 years and a BMI of 25±4.02. The mean serum magnesium level was 1.77±0.26 mg/dL, while the mean serum calcium level was 9.1±0.63 mg/dL. Notably, serum magnesium levels were significantly lower in the diastolic notch group compared to the non-notch group (p=0.048), and serum calcium levels were significantly higher in the diastolic notch group (p=0.002). CONCLUSIONS This study suggests a significant association between the presence of a diastolic notch in uterine artery Doppler ultrasonography and altered serum levels of magnesium and calcium. These findings may provide a predictive marker for placental dysfunctions such as preeclampsia and intrauterine growth restriction. Further large-scale studies are needed to confirm these associations and explore their clinical utility.
Kubat Küçükyurt A, Kolcu SA, Basat D, Bingöl BB, Tanrikulu C, Yildiz E, Medical science monitor : international medical journal of experimental and clinical research
Magnesium deficiency score predicts erectile dysfunction risk and mortality.
BACKGROUND: Magnesium deficiency is associated with numerous cardiovascular and metabolic disorders, which are established risk factors for erectile dysfunction (ED). However, the role of the magnesium depletion score (MDS)-a composite measure of magnesium status-in relation to ED and subsequent mortality remains unclear. METHODS: We analyzed data from 3,917 participants in the National Health and Nutrition Examination Survey (NHANES) 2001-2004. Weighted multivariable logistic and Cox proportional hazards models were used to examine associations between MDS and ED and between MDS and mortality, respectively. Sensitivity analyses included subgroup analyses and propensity score matching. RESULTS: Of the participants, 1,090 were identified with ED. During follow-up, 654 deaths occurred. After full adjustment, each 1-point increase in MDS was associated with a 37% higher prevalence of ED (OR = 1.37, 95% CI: 1.16-1.62). Among those with ED, higher MDS was also associated with a 30% increased risk of all-cause mortality (HR = 1.30, 95% CI: 1.17-1.45). Sensitivity analyses supported the robustness of these findings. CONCLUSION: Higher MDS is significantly associated with both increased prevalence of ED and greater all-cause mortality in men with ED. These results underscore the importance of assessing magnesium status as a potential target for risk stratification and nutritional intervention in the management of ED.
Xiaobao Chen, Kangqiang Weng, Ruoyun Xie, Junwei Lin, Lingjun Liu, Shaoxing Zhu, Huaiying Zheng, Front Nutr
Human Study
Effects of Preoperative Magnesium Sulphate Infusion on Emergence Agitation and Postoperative Quality of Recovery in Patients Undergoing Thoracoscopic Lobectomy.
BACKGROUND: Emergence agitation(EA) is common in the early phase of recovery from general anesthesia in adults, which can potentially cause unpredictable harm to both patients and medical staff. This study aimed to examine the effects of preoperative magnesium sulphate infusion on emergence agitation and postoperative quality of recovery in patients undergoing thoracoscopic lobectomy. PATIENTS AND METHODS: 84 patients undergoing thoracoscopic lobectomy were randomly assigned to either the magnesium sulphate group (group M) or the control group (group C). Group M received a 50 mg/ kg intravenous bolus of magnesium sulphate 20 minutes before induction, whereas group C was administered an equivalent volume of saline. The Riker Sedation-Agitation Scale (SAS) and the 40-item Quality of Recovery questionnaire (QoR-40) were used to evaluate emergence agitation and postoperative quality of recovery, respectively. RESULTS: In comparison to group C, group M demonstrated a significantly lower incidence of EA (9.5% vs 42.9%; OR, 0.14; 95% CI, 0.04-0.47; < 0.001) and dangerous agitation (0% vs 14.3%; OR, 2.17; 95% CI, 1.71-2.75; =0.011), along with a reduction in the maximal SAS score ( < 0.05). Group M exhibited higher global QoR-40 scores than group C on postoperative day 1 (POD 1)(168.3±13.8 vs 155.6±16.5, <0.001). Additionally, group M displayed lower Numerical rating scale (NRS) pain scores both at rest and during coughing in PACU and on POD 1 ( < 0.001). There were no significant statistically differences between the two groups in terms of time to extubation, incidence of delayed recovery and residual sedation ( > 0.05). CONCLUSION: Preoperative magnesium sulphate infusion effectively decreased the incidence and severity of EA in patients undergoing thoracoscopic lobectomy. Furthermore, it alleviated postoperative pain and improved postoperative quality of recovery, without an increase in adverse events.
Pu Y, Geng X, Wang M, Lv G, Hu Z, Fang C, Zhang X, Li W, Fan X, Chen X, Drug design, development and therapy
Videos (6)
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May 11, 2014
The Top 5 Supplements Everyone Should Take
Dr. Ann Louise Gittleman discusses some of the top supplements a person should consider taking to manage their health. She mentions a number of common supplements but also some important things to loo...
612 views
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Jan 12, 2014
Interesting Facts About Quinoa (Infographic)
Did you know that one serving of quinoa fills 48 percent of our daily magnesium needs? Check out these interesting facts about one of our favorite superfoods…
299 views
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Sep 9, 2013
Magnesium:"The Most Powerful Relaxation Mineral Available"
Could a deficiency in a magnesium be to blame for some of your chronic health problems, lack of sleep or anxiety? Mark Hyman, M.D. reveals why this "secret antidote to [...]
295 views
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Feb 11, 2014
Health Benefits of Magnesium
There are a number of foods with an abundant supply of magnesium…
187 views
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Dec 15, 2013
Here is Why Magnesium Is So Important
Magnesium is just one of the many minerals your body needs. In this video, Max Motyka describes the many functions that relay on adequate magnesium in the body. He also[Read More...]
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