Search Research
Search across 105,000+ research abstracts, articles, substances, health topics, keywords, and actions.
Found 11 results for "aminomethylphosphonic acid"
Articles (5)
Jan 19, 2014
New Study Renews Roundup 'Weedkiller' Toxicity Concern
A new study published in the January issue of International Journal of Toxicology titled, " Glyphosate
Sayer Ji
4 min
Dec 05, 2024
Unveiling the Corporate Agenda Behind the Global Plant-Based Food Movement
Originally published on www.orthomolecular.org by Richard Z. Cheng, M.D., Ph.D. The perception of plant-based foods as superior is largely shaped by corporate marketing rather than balanced evidence...
OrthomolecularNewsService
19 min
Jun 19, 2013
Think the Anti-GMO Movement is Unscientific? Think Again
\ "Anyone that says, 'Oh, we know that this is perfectly safe,' I say is either
Sayer Ji
6 min
Feb 19, 2012
New Research: GMO Food Far Worse Than We Think
Disturbing new research published in the Journal of Applied Toxicology indicates that genetically modified (GM
<p>Sayer Ji is the founder and chair of GreenMedInfo.com. His writings have been published in the Wellbeing Journal, the Journal of Gluten Sensitivity, and have been featured on numerous websites, including Mercola.com, NaturalNews.com, Infowars.com, Care2.com. His critically acclaimed essay series The Dark Side of Wheat opens up a new perspective on the universal, human-species specific<strong> </strong><strong><a href="/product/dark-side-wheat-pdf-document">toxicity of wheat</a></strong>, and is now available for PDF download.</p>
2 minAbstracts (6)
View allAssociations of glyphosate and aminomethylphosphonic acid (AMPA) concentrations with birth outcomes in pregnant women from the Midwestern U.S.
BACKGROUND: Pregnant women are ubiquitously exposed to the herbicide glyphosate and its major metabolite aminomethylphosphonic acid (AMPA). Therefore, we examined associations of glyphosate and AMPA with birth outcomes. METHODS: Pregnant women from the Illinois Kids Development Study (I-KIDS) participating in this pilot study (n = 300) provided first-morning urine samples at median 13-weeks gestation for glyphosate and AMPA measurement. We calculated gestational-age-at-birth using the last menstrual period after ultrasound confirmation, abstracted birthweight from electronic medical records, and calculated sex-specific birthweight-for-gestational-age z-scores (BWz). We measured birth length (cm) and anogenital distance (AGD) within 24 h of birth and calculated the anogenital index (AGI, mm/m) by dividing each AGD value (in mm) by the body length (in m). Multivariable linear regression models evaluated associations of glyphosate or AMPA with birth outcomes and differences in associations by newborn sex. RESULTS: In all newborns, only 2-fold higher AMPA was associated with -0.07 cm shorter birth length (95 %CI: -0.16, 0.02). In males, each 2-fold higher glyphosate was associated with -0.06 lower BWz (95 % CI: -0.13, 0.01), -0.14 cm shorter birth length (95 %CI: -0.31, 0.04), and 0.63 longer AGI(95 %CI: -0.19, 1.44). In females, each two-fold higher glyphosate was associated with 0.54 longer AGI(95 %CI: -0.16, 1.25). AMPA was associated with 0.61 (95 %CI: -0.01, 1.24) and 0.48 (95 %CI: 0.02, 0.94) longer AGIin males and females, respectively. Some associations gained precision in sensitivity analyses removing infants born preterm or after controlling for gestational-age-at-birth. CONCLUSIONS: Glyphosate or AMPA were associated with smaller birth size and longer AGI, with evidence of sexual-dimorphism, although most findings were imprecise. Larger studies are needed, including those that consider implications of these findings for child lifelong health.
Kelsi A Morris, Maria E Cinzori, Brad A Ryva, Nicole Talge, Khyatiben V Pathak, Brooke Lovell, Patrick Pirrotte, Susan L Schantz, Rita S Strakovsky, Int J Hyg Environ Health
Human Study
Simultaneous Determination of Glyphosate, Aminomethylphosphonic Acid, and Glufosinate in Green Coffee Beans by LC-MS/MS: Optimization, Validation, and Field Study.
Despite the widespread use of glyphosate in coffee crops, there is a lack of simple, low-cost, validated methods for detecting glyphosate and related compounds in green coffee beans, the primary export form subject to international regulation. This study optimized and validated a liquid chromatography with tandem mass spectrometry method for the determination of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate in green coffee, using a modified QuPPe-PO extraction followed by a cleanup combining liquid-liquid extraction and dispersive solid-phase extraction. Validation followed SANTE/11312/2021 guidelines, confirming the method's linearity, precision, accuracy, and quantification limits. Limits of quantification were 0.02 mg kg (glyphosate), 0.04 mg kg (AMPA), and 0.01 mg kg (glufosinate). The method was applied to a field study with Arabica coffee and Conilon Coffee, revealing that plant height was the primary factor influencing residue levels. The proposed method enables reliable monitoring of polar herbicides in coffee without the need for derivatization.
da Silva JCRM, Avelar MCF, Ribeiro MCM, Almeida MO, de Faria VHF, Osório VM, Faria AF, Journal of agricultural and food chemistry
Metal-dependant structural families of aminomethylphosphonic acid assemblies differentiated by ion mobility mass spectrometry and density functional theory.
Herein the morphology of aminomethylphosphonic acid (AMPA)-metal aggregates are analysed by ion mobility-mass spectrometry, DFT and IRMPD spectroscopy. Matching experimental collision cross section to the DFT predicted minima allowed unambiguous assignment of [M(AMPA)(AMPA-H)] where M = Mg, Ca, and Mn. Two distinct structural families of [M(AMPA)(AMPA-H)] where M = Mg, Ca, Sr, Ba, Mn, Cu, and Zn were differentiated by ion mobility mass spectrometry. Groupings of experimental collision cross sections were observed for a square pyramidal geometry, (M = Ca, Sr, Ba) a seesaw geometry (M = Mg, Mn, Cu, and Zn), paving the way for distinction of aggregates at the earliest stages of assembly.
Rusli O, Mun H, Neumaier M, Bakels S, Hes K, Lloyd Williams OH, Rijs AM, Ho J, Rijs NJ, Chemical communications (Cambridge, England)
Rapid and simple method for glyphosate, aminomethylphosphonic acid, and sarcosine pre-concentration and determination in environmental samples after molecularly imprinted solid-phase extraction.
This study presents a selective and efficient analytical method for the simultaneous determination of glyphosate (GLY), aminomethylphosphonic acid (AMPA), and sarcosine (SAR) in environmental water and honey samples using commercial molecularly imprinted solid-phase extraction (MIP-SPE) coupled with tosyl chloride-based derivatization and high-performance liquid chromatography with UV detection (HPLC-UV). A central composite design (CCD) was employed to optimize key extraction parameters, including pH, sample volume, flow rate, and analyte concentration. Under optimized conditions, extraction recoveries exceeded 98 % for all analytes. Elution was optimized using 100 mM HCl, which provided superior recovery compared to basic eluents. The method showed excellent linearity (R > 0.99), low detection limits (<0.4 μgL), and high precision (RSD<1.5 %). Application to real wastewater, river water, and honey samples confirmed high recoveries and minimal matrix interference. This validated MIP-SPE-HPLC-UV procedure provides a robust, cost-effective, and environmentally friendly solution for monitoring trace levels of polar contaminants in complex matrices.
Shamsi Z, Haderlein SB, Environmental pollution (Barking, Essex : 1987)
Liver metabolomic alterations in hatchlings of invasive turtle, Trachemys scripta elegans, following egg exposure to glyphosate-isopropylammonium or aminomethylphosphonic acid.
Potential adverse impacts of residual agricultural chemicals and their by-products in soil are generally overlooked in oviparous reptiles. Herein, eggs of an invasive turtle, Trachemys scripta elegans, were incubated on moist substrate with different levels of a glyphosate formulation (glyphosate-isopropylammonium, Gly-IPA) or glyphosate by-product (aminomethylphosphonic acid, AMPA), and then embryonic development, hatchling functional performance and liver metabolomic profile were investigated to evaluate herbicide residue effects in turtle species. No significant alterations in egg survival and incubation length, as well as hatchling size and locomotor performance were observed after egg exposure. Metabolomic analysis revealed only slight alterations in some liver metabolites, probably reflecting mild metabolic disorders caused by embryonic exposure to Gly-IPA or AMPA in T. scripta elegans. Overall, effect of embryonic exposure to Gly-IPA or AMPA on functional and metabolic performances of turtle hatchings might be relatively weak.
Si YX, Tang HB, Zhang Y, Yang JM, Gao JF, Lu HL, Ecotoxicology (London, England)
