Acetyl-l-carnitine

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66 Diseases Researched for Acetyl-l-carnitine
NameACCKFocus
Neuropathic Pain1184Locked
HIV Drug-Induced Toxicity 440Locked
HIV Infections440Locked
Chemotherapy-Induced Toxicity: Peripheral Neuropathy431Locked
Fibromyalgia330Locked
Depression321Locked
Chemotherapy-Induced Toxicity: Cisplatin220Locked
Chemotherapy-Induced Toxicity: Paclitaxel220Locked
Elderly: Age Specific Diseases220Locked
Insulin Resistance220Locked
Sperm Quality: Low220Locked
Colitis115Locked
Inflammation115Locked
Inflammatory Bowel Diseases115Locked
Diabetes Mellitus: Type 2212Locked
Infertility: Male212Locked
Allodynia110Locked
Ammonia: Elevated110Locked
Asthenozoospermia110Locked
Brain Damage110Locked
Coronary Artery Disease110Locked
Dementia: Vascular110Locked
Endothelial Dysfunction110Locked
Head Injuries110Locked
Hepatic Encephalopathy110Locked
Human Growth Hormone: Enhancement110Locked
Low Back Pain110Locked
Neuropathy: Small Fiber110Locked
Oxidative Stress610Locked
Polycystic Ovary Syndrome110Locked
Stroke: Ischemic110Locked
Traumatic Brain Injury110Locked
Alzheimer's Disease47Locked
Aging: Brain 35Locked
Pain24Locked
Peripheral Neuropathies34Locked
Aging12Locked
Alcohol Toxicity 12Locked
Arsenic Poisoning12Locked
Atherosclerosis12Locked
Autism Spectrum Disorders12Locked
Brain Injury: Traumatic12Locked
Cataract12Locked
Cognitive Decline/Dysfunction12Locked
DNA damage12Locked
Demyelinating Diseases12Locked
Diabetes: Cardiovascular Illness12Locked
Diabetic Neuropathies12Locked
HIV Protease Inhibitor Ritonavir Toxicity12Locked
Hypercholesterolemia12Locked
Leptin Resistance12Locked
Memory Disorders12Locked
Memory Loss12Locked
Mitochondrial Diseases12Locked
Mitochondrial Dysfunction 12Locked
Muscle Fatigue12Locked
Neuropathies12Locked
Pain: Chronic12Locked
Pelvic Inflammatory Disease12Locked
Radiation Induced Illness12Locked
Seizures12Locked
Brain Ischemia11Locked
Colorectal Cancer11Locked
Covid: Long11Locked
Obesity11Locked
Attention Deficit Disorder with Hyperactivity10Locked
22 Pharmacological Actions Researched for Acetyl-l-carnitine
NameACCKFocus
Neuroprotective Agents1032Locked
Anti-Inflammatory Agents429Locked
Antioxidants925Locked
Analgesics524Locked
Insulin Sensitizers220Locked
Reverse Transcriptase Inhibitors220Locked
Anti-HIV Agents110Locked
Hypoglycemic Agents110Locked
Neurorestorative110Locked
Vasodilator Agents110Locked
Analgesics: Non-Narcotic12Locked
Anti-Apoptotic12Locked
Anticholesteremic Agents12Locked
Anticonvulsants12Locked
Cardioprotective12Locked
Fertility Agents: Male12Locked
Gastrointestinal Agents12Locked
Radioprotective12Locked
Antidepressive Agents11Locked
Antinoceceptive 11Locked
Apoptotic11Locked
Chemotherapeutic11Locked
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View the Evidence:
58 Abstracts with Acetyl-l-carnitine Research

[+]

The intestinal microbial metabolite acetyl l-carnitine improves gut inflammation and immune homeostasis via CADM2.Mar 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochim Biophys Acta Mol Basis Dis. 2024 Apr ;1870(4):167089. Epub 2024 Feb 16. PMID: 38369215
Article Published Date : Mar 31, 2024
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Colitis, Inflammation, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A nutrient combination improves cognitive function in head injuried former NFL players. Jan 01, 2011

Pubmed Data : J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5. PMID: 21615001
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Fish Oil, Ginkgo biloba, Huperzine, Multivitamin, NAC (N-acetyl-L-cysteine), Vinpocetine
Diseases : Brain Damage, Head Injuries, Traumatic Brain Injury
Pharmacological Actions : Neurorestorative
[+]

Acetyl L-carnitine has a therapeutic effect in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection.May 01, 2007

Pubmed Data : HIV Med. 2007 May;8(4):241-50. PMID: 17461852
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : HIV Drug-Induced Toxicity , HIV Infections, Neuropathic Pain
Pharmacological Actions : Anti-HIV Agents
[+]

Acetyl L-carnitine treatment improves symptoms and causes peripheral nerve regeneration in HIV-associated anteretroviral toxic neuropathy. Jul 23, 2004

Pubmed Data : AIDS. 2004 Jul 23;18(11):1549-60. PMID: 15238773
Article Published Date : Jul 23, 2004
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : HIV Drug-Induced Toxicity , HIV Infections, Neuropathic Pain
Pharmacological Actions : Reverse Transcriptase Inhibitors
[+]

Acetyl L-carnitine treatment improves symptoms of chemotherapy induced neuropathy. Aug 01, 2005

Pubmed Data : Eur J Cancer. 2005 Aug;41(12):1746-50. PMID: 16039110
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Neuropathic Pain
[+]

Acetyl-L-carnitine ameliorates metabolic and endocrine alterations in women with PCOS.Jun 30, 2021

Pubmed Data : Adv Ther. 2021 Jul ;38(7):3842-3856. Epub 2021 May 28. PMID: 34047916
Article Published Date : Jun 30, 2021
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Insulin
[+]

Acetyl-l-carnitine and Ornithine may help to facilitate night time growth hormone release.May 01, 2001

Pubmed Data : Med Hypotheses. 2001 May;56(5):610-3. PMID: 11388776
Article Published Date : May 01, 2001
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Ornithine
Diseases : Human Growth Hormone: Enhancement
[+]

Acetyl-L-carnitine appears to be an effective and well-tolerated agent for the treatment of chemotherapy-induced peripheral neuropathy.Mar 01, 2005

Pubmed Data : Tumori. 2005 Mar-Apr;91(2):135-8. PMID: 15948540
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Neuropathic Pain
Additional Keywords : Drug: Cisplatin
[+]

Acetyl-L-carnitine as an add-on treatment in fibromyalgia syndrome.Mar 27, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2025 Mar 28 ;13(4). Epub 2025 Mar 28. PMID: 40299412
Article Published Date : Mar 27, 2025
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Fibromyalgia
[+]

Acetyl-l-carnitine has a neuroprotective effect against chemotherapy-induced allodynia. May 01, 2005

Pubmed Data : In Vivo. 2005 May-Jun;19(3):631-7. PMID: 15875786
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Allodynia, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Neuroprotective Agents
[+]

Acetyl-L-carnitine has a positive long-term effect in the treatment of antiretroviral toxic neuropathy.Nov 01, 2005

Pubmed Data : HIV Clin Trials. 2005 Nov-Dec;6(6):344-50. PMID: 16566084
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : HIV Drug-Induced Toxicity , HIV Infections, Neuropathic Pain
Pharmacological Actions : Reverse Transcriptase Inhibitors
[+]

Acetyl-l-carnitine improves depression in senile patients.Jan 01, 1990

Pubmed Data : Drugs Exp Clin Res. 1990;16(2):101-6. PMID: 2205455
Article Published Date : Jan 01, 1990
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Depression, Elderly: Age Specific Diseases
[+]

Acetyl-L-carnitine is effective in the treatment of early stages of Alzheimer's disease and vascular dementiaJan 01, 2011

Pubmed Data : Zh Nevrol Psikhiatr Im S S Korsakova. 2011 ;111(9):16-22. PMID: 22027664
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Dementia: Vascular
[+]

Acetyl-l-carnitine may have therapeutic properties in geriatric depression.Dec 01, 2003

Pubmed Data : Int J Neurosci. 2003 Dec;113(12):1691-701. PMID: 12047496
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Depression, Elderly: Age Specific Diseases
[+]

Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy.Apr 24, 2006

Pubmed Data : Neurosci Lett. 2006 Apr 24;397(3):219-23. Epub 2006 Jan 6. PMID: 16406309
Article Published Date : Apr 24, 2006
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
[+]

Acetyl-l-carnitine was effective and well tolerated in symptomatic treatment of painful neuropathy associated with antiretroviral toxicity.Mar 01, 2006

Pubmed Data : J Peripher Nerv Syst. 2006 Mar;11(1):72-6. PMID: 16519785
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : HIV Drug-Induced Toxicity , HIV Infections, Neuropathic Pain
[+]

Alpha-Lipoic acid and acetyl-L-carnitine appear to improve vascular function and blood pressure in patients with coronary artery disease. Apr 01, 2007

Pubmed Data : J Clin Hypertens (Greenwich). 2007 Apr;9(4):249-55. PMID: 17396066
Article Published Date : Apr 01, 2007
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, B-complex
Diseases : Coronary Artery Disease, Endothelial Dysfunction
Pharmacological Actions : Vasodilator Agents
[+]

Carnitine supplementation improved insulin sensitivity and tended to lower IHL and fasting plasma glucose levels in patients with type 2 diabetes.Apr 30, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Obes Metab. 2025 May ;27(5):2864-2877. Epub 2025 Feb 28. PMID: 40019115
Article Published Date : Apr 30, 2025
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Carnitine
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers
[+]

Clinical evidence of acetyl-L-carnitine efficacy in the treatment of acute ischemic stroke.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:2493053. Epub 2022 Jul 29. PMID: 35936217
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Combined treatment with l-carnitine and l-acetyl-carnitine in a controlled study of efficacy was effective in increasing sperm motility.Jun 01, 2004

Pubmed Data : Fertil Steril. 2004 Jun;81(6):1578-84. PMID: 15193480
Article Published Date : Jun 01, 2004
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Carnitine
Diseases : Infertility: Male, Sperm Quality: Low
[+]

L-carnitine and acetyl-L-carnitine may transiently improve neuronal function in cirrhotic patients with persistent hepatic encephalopathy and hyperammonaemia.Jan 01, 2006

Pubmed Data : Clin Exp Pharmacol Physiol. 2006 Jan-Feb;33(1-2):76-80. PMID: 16445703
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Carnitine
Diseases : Ammonia: Elevated, Hepatic Encephalopathy
[+]

Palmitoylethanolamide and acetyl-L-carnitine act synergistically with duloxetine and pregabalin in fibromyalgia.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Rheumatol. 2023 Jun ;41(6):1323-1331. Epub 2023 Jun 28. PMID: 37378482
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Palmitoylethanolamide
Diseases : Fibromyalgia
Pharmacological Actions : Analgesics
Additional Keywords : Natural Substance/Drug Synergy
[+]

Prophylactic acetyl-L-carnitine treatment against paclitaxel-evoked pain may be related to a protective effect on C-fiber mitochondria.Mar 01, 2008

Pubmed Data : Exp Neurol. 2008 Mar;210(1):229-37. Epub 2007 Nov 17. PMID: 18078936
Article Published Date : Mar 01, 2008
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
Additional Keywords : Drug: Paclitaxel
[+]

These results suggest that adding LAC and PEA to standard care may provide meaningful symptom relief for fibromyalgia patients with suspected small fiber involvement.Jul 30, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2025 Jul 31 ;17(8). Epub 2025 Jul 31. PMID: 40871024
Article Published Date : Jul 30, 2025
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Palmitoylethanolamide
Diseases : Fibromyalgia, Neuropathy: Small Fiber
[+]

This combination of natural substances has potential to improve pain and reduce reliance on conventional therapies in lower back pain.Jul 31, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Neurol. 2025 Aug ;32(8):e70334. PMID: 40853095
Article Published Date : Jul 31, 2025
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Frankincense, Vitamin B-6, Vitamin E
Diseases : Low Back Pain
Pharmacological Actions : Analgesics
[+]

Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia.Sep 01, 2010

Pubmed Data : Minerva Urol Nefrol. 2010 Sep;62(3):213-8. PMID: 20940690
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Arginine, Carnitine, Ginseng
Diseases : Asthenozoospermia, Sperm Quality: Low
[+]

A combination of mitochondrial targeting nutrients may improve skeletal mitochondrial dysfunction and exert hypoglycemic effects, without causing weight gain.Jan 01, 2008

Pubmed Data : PLoS One. 2008;3(6):e2328. Epub 2008 Jun 4. PMID: 18523557
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Biotin, Niacin
Diseases : Diabetes Mellitus: Type 2, Mitochondrial Diseases, Mitochondrial Dysfunction
[+]

Acetyl L-carnitine exhibits pain-killing activity in an animal model of neuropathy.Dec 01, 2002

Pubmed Data : Neuropharmacology. 2002 Dec;43(7):1180-7. PMID: 12504925
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Neuropathic Pain, Pain
Pharmacological Actions : Analgesics
[+]

Acetyl L-carnitine protects Zebrafish embryos from verapamil and Inorganic arsenic-Induced cardiotoxicity and developmental toxicity.Jul 31, 2025

Pubmed Data : J Appl Toxicol. 2025 Aug ;45(8):1535-1546. Epub 2025 Apr 15. PMID: 40234040
Article Published Date : Jul 31, 2025
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Arsenic Poisoning
Pharmacological Actions : Cardioprotective
Problem Substances : Arsenic
[+]

Acetyl-L-carnitine aids in preservation of cholinergic neurons and memory in the Drosophila melanogaster model of Alzheimer's disease.Dec 31, 2023

Pubmed Data : Curr Alzheimer Res. 2024 ;21(8):557-565. PMID: 39716786
Article Published Date : Dec 31, 2023
Study Type : Insect Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Acetyl-l-carnitine alleviates valproate-induced autism-like behaviors through attenuation of hippocampal mitochondrial dysregulation.Oct 17, 2024

Pubmed Data : Neuroscience. 2024 Oct 18 ;558:92-104. Epub 2024 Aug 20. PMID: 39168175
Article Published Date : Oct 17, 2024
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Autism Spectrum Disorders, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Acetyl-L-carnitine ameliorates atherosclerosis in LDLR-/- mice by modulating cholesterol metabolism.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2024 ;11:1509577. Epub 2024 Dec 16. PMID: 39737151
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Atherosclerosis, Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents
[+]

Acetyl-l-carnitine and R-alpha-lipoic acid partially reverses brain decay and RNA/DNA oxidation associated with memory loss in rats. Feb 19, 2002

Pubmed Data : Proc Natl Acad Sci U S A.2002 Feb 19;99(4):2356-61. PMID: 11854529
Article Published Date : Feb 19, 2002
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid
Diseases : Aging: Brain , DNA damage, Memory Disorders, Memory Loss
Pharmacological Actions : Neuroprotective Agents
[+]

Acetyl-l-carnitine and resveratrol has a protective effect against chemically-induced peripheral neuropathy in rats.Aug 16, 2010

Pubmed Data : Neurosci Lett. 2010 Aug 16;480(2):117-21. Epub 2010 Jun 11. PMID: 20542088
Article Published Date : Aug 16, 2010
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Resveratrol
Diseases : Peripheral Neuropathies
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Stilbenes
[+]

Acetyl-L-carnitine attenuates chronic ethanol-induced oxidative stress, ER stress and apoptosis in rat gastric tissue.Oct 31, 2023

Pubmed Data : Alcohol. 2023 Nov ;112:51-59. Epub 2023 Jul 25. PMID: 37499932
Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Carnitine
Diseases : Alcohol Toxicity , Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Gastrointestinal Agents
[+]

Acetyl-l-carnitine has a protective effect against radiation-induced oxidative stress in rats.Sep 01, 2006

Pubmed Data : Pharmacol Res. 2006 Sep;54(3):165-71. Epub 2006 May 1. PMID: 16757176
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Radiation Induced Illness
Pharmacological Actions : Antioxidants, Radioprotective
[+]

Acetyl-l-carnitine has anti-cataractogenic properties. Dec 01, 2006

Pubmed Data : Exp Eye Res. 2006 Dec;83(6):1340-9. Epub 2006 Sep 8. PMID: 16962580
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Cataract, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Sodium Selenite
[+]

Acetyl-l-carnitine increases nerve regeneration and target organ reinnervation. Feb 01, 2005

Pubmed Data : Clin Biochem. 2005 Feb;38(2):191-6. PMID: 19664977
Article Published Date : Feb 01, 2005
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Demyelinating Diseases
[+]

Acetyl-l-carnitine is an analgesic. May 01, 2002

Pubmed Data : Mol Pharmacol.2002 May;61(5):989-96. PMID: 11961116
Article Published Date : May 01, 2002
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Pain, Pain: Chronic
Pharmacological Actions : Analgesics: Non-Narcotic
[+]

Acetyl-l-carnitine supplementation may reduce muscle fatigue by increasing fat oxidation. Sep 01, 2008

Pubmed Data : Proteomics.2008 Sep;8(17):3588-604. PMID: 18686300
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Muscle Fatigue
[+]

Acetyl-l-carnitine supplementation partly reduces the leptin resistance that occurs in old rats, and improves ATP production in skeletal muscle mitochondria through an increase in mitochondrial protein content.Apr 01, 2002

Pubmed Data : J Nutr.2002 Apr;132(4):636-42. PMID: 11925454
Article Published Date : Apr 01, 2002
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Aging, Leptin Resistance
[+]

Antioxidant and gamma linolenic acid have a protective effect against nerve and vascular dysfunction in experimental diabetes. Sep 01, 1999

Pubmed Data : Diabetes Res Clin Pract. 1999 Sep;45(2-3):137-46. PMID: 10588366
Article Published Date : Sep 01, 1999
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Gamma-Linoleic Acid (GLA) , Vitamin E
Diseases : Diabetes: Cardiovascular Illness, Diabetic Neuropathies
Pharmacological Actions : Antioxidants
[+]

Coenzyme Q10 and acetyl-l-carnitine prevents antiretroviral toxic neuropathy in an in vitro model.Apr 01, 2010

Pubmed Data : Curr HIV Res. 2010 Apr 1;8(3):232-9. PMID: 20158454
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Coenzyme Q10
Diseases : HIV Protease Inhibitor Ritonavir Toxicity, Neuropathies
[+]

Effects of N-acetylcysteine and acetyl-L-carnitine on acute PTZ-induced seizures in larval and adult zebrafish.Nov 30, 2023

Pubmed Data : Pharmacol Rep. 2023 Dec ;75(6):1544-1555. Epub 2023 Oct 9. PMID: 37814098
Article Published Date : Nov 30, 2023
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, NAC (N-acetyl-L-cysteine)
Diseases : Seizures
Pharmacological Actions : Anticonvulsants
[+]

Enhanced inflammatory and oxidative response mitigation by acetyl-L-carnitine in a rat model of pelvic inflammatory disease.Jun 30, 2025

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2025 Jul ;398(7):9215-9224. Epub 2025 Feb 6. PMID: 39912899
Article Published Date : Jun 30, 2025
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Oxidative Stress, Pelvic Inflammatory Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

L-carnitine and acetyl-L-carnitine: A novel approach to treating male infertility with abnormal sperm morphology.Apr 30, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2025 May ;17(Suppl 1):S1038-S1041. Epub 2025 Apr 12. PMID: 40511105
Article Published Date : Apr 30, 2025
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, L-Carnitine
Diseases : Infertility: Male
Pharmacological Actions : Fertility Agents: Male
[+]

R-lipoic acid and acetyl-l-carnitine ameliorate age-associated oxidative damage to the brain, in a rat experimental model. Apr 01, 2009

Pubmed Data : Neurochem Res. 2009 Apr;34(4):755-63. Epub 2008 Oct 10. PMID: 18846423
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid
Diseases : Aging: Brain , Alzheimer's Disease, Cognitive Decline/Dysfunction
[+]

Repetitive mild traumatic brain injury-induced neurodegeneration and inflammation is attenuated by acetyl-L-carnitine.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1254382. Epub 2023 Sep 8. PMID: 37745053
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Vitamin E, acetyl-l-carnitine and α-lipoic acid are superior to the drug donepezil (Aricept) at normalizing biomarkers associated with Alzheimer's disease in an animal model. Dec 23, 2010

Pubmed Data : Exp Toxicol Pathol. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21183322
Article Published Date : Dec 23, 2010
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Vitamin E
Diseases : Alzheimer's Disease
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

A comprehensive review of safety, efficacy, and indications for the use of alpha-lipoic acid and acetyl-L-carnitine in neuropathic pain.Jun 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Med (Encinitas). 2024 Jul ;23(3):32-39. PMID: 39114278
Article Published Date : Jun 30, 2024
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid
Diseases : Neuropathic Pain
Pharmacological Actions : Analgesics, Neuroprotective Agents
Additional Keywords : Nerve Regeneration
[+]

Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model.May 31, 2015

Pubmed Data : J Neural Transm (Vienna). 2015 Jun ;122(6):867-72. Epub 2014 Nov 29. PMID: 25432433
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Brain Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Acetyl-l-carnitine delays the mitochondrial decay of aging and improves cognitive function in Alzheimers disease. Apr 01, 1999

Pubmed Data : Planta Med. 1999 Apr;65(3):266-8. PMID: 15591008
Article Published Date : Apr 01, 1999
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Aging: Brain , Alzheimer's Disease
[+]

Acetyl-l-carnitine has significant therapeutic value in the treatment of neuropathic pain. Jan 01, 2007

Pubmed Data : CNS Drugs.2007;21 Suppl 1:31-8; discussion 45-6. PMID: 17696591
Article Published Date : Jan 01, 2007
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Neuropathic Pain, Peripheral Neuropathies
Pharmacological Actions : Antinoceceptive
[+]

Acetyl-l-carnitine has therapeutic activity in treating chemotherapy-induced peripheral neuropathy. Jan 01, 2007

Pubmed Data : CNS Drugs. 2007;21 Suppl 1:39-43; discussion 45-6. PMID: 17696592
Article Published Date : Jan 01, 2007
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Peripheral Neuropathies
[+]

L-carnitine and acetyl-L carnitine: A possibility for treating alterations induced by obesity in the central nervous system.Oct 31, 2023

Pubmed Data : Neurochem Res. 2023 Nov ;48(11):3316-3326. Epub 2023 Jul 27. PMID: 37495838
Article Published Date : Oct 31, 2023
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine, Carnitine
Diseases : Obesity, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Neuropsychiatric manifestations of COVID-19 disease and post COVID syndrome: The role of N-acetylcysteine and Acetyl-L-carnitine.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Neuropharmacol. 2025 ;23(6):686-704. PMID: 39506442
Article Published Date : Dec 31, 2024
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine, NAC (N-acetyl-L-cysteine)
Diseases : Covid: Long, Depression
Pharmacological Actions : Analgesics, Antidepressive Agents, Neuroprotective Agents
Additional Keywords : Long Covid
[+]

The results highlight l-carnitine and acetyl-l-carnitine as promising agents to target CRC metabolic vulnerabilities. Mar 12, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2025 Mar 13 ;17(6). Epub 2025 Mar 13. PMID: 40290068
Article Published Date : Mar 12, 2025
Study Type : In Vitro Study
Additional Links
Substances : Acetyl-l-carnitine, L-Carnitine
Diseases : Colorectal Cancer, Oxidative Stress
Pharmacological Actions : Apoptotic, Chemotherapeutic
[+]

Acetyl-L-Carnitine represents a safe alternative to stimulant drugs in the treatment of ADHDApr 01, 2008

Pubmed Data : Am J Med Genet A. 2008 Apr 1;146(7):803-12. PMID: 18286595
Article Published Date : Apr 01, 2008
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Attention Deficit Disorder with Hyperactivity

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