Andrographis

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47 Diseases Researched for Andrographis
NameACCKFocus
Influenza211Locked
Cold and Flu110Locked
Common Cold110Locked
Familial Mediterranean Fever110Locked
Osteoarthritis: Knee110Locked
Respiratory Tract Infections110Locked
Rheumatoid Arthritis110Locked
Sinusitis110Locked
Upper Respiratory Infections110Locked
Liver Cancer45Locked
Cancer Metastasis33Locked
Cancers: All33Locked
Lymphoma23Locked
Avian Influenza12Locked
Chemically-Induced Liver Damage12Locked
Colon Cancer22Locked
Colorectal Cancer22Locked
Diabetic Nephropathy12Locked
Esophageal Cancer12Locked
H1N1 Infection12Locked
Immune Disorders: Low Immune Function12Locked
Influenza A12Locked
Kidney Diseases12Locked
Lymph Node Cancer12Locked
Malaria12Locked
Nephropathy: Diabetic12Locked
Pesticide Toxicity 12Locked
Streptococcus Infections12Locked
Allergies11Locked
Cancer Stem Cells11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Diabetes Mellitus: Type 111Locked
Epstein-Barr Virus Infections11Locked
Follicular Lymphoma11Locked
Gastric Cancer11Locked
H5N1 Infection11Locked
Inflammation11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Lung Cancer11Locked
Multiple Myeloma11Locked
Multiple Sclerosis11Locked
Non-Hodgkin's lymphoma: B Cell11Locked
Promyelocytic leukemia 11Locked
Prostate Cancer11Locked
Protozoan Infections11Locked
Rectal Cancer11Locked
Skin Cancer: Squamous Cell11Locked
30 Pharmacological Actions Researched for Andrographis
NameACCKFocus
Analgesics212Locked
Immunomodulatory46Locked
Anti-metastatic45Locked
Apoptotic55Locked
Antineoplastic Agents44Locked
Antioxidants24Locked
Antiproliferative 23Locked
Anti-Bacterial Agents12Locked
Anti-Inflammatory Agents22Locked
Anti-edemic12Locked
Anticarcinogenic Agents12Locked
Hepatoprotective12Locked
Renoprotective12Locked
Viral Hemagglutinin Inhibitor12Locked
Anti-Angiogenic11Locked
Antiprotozoal Agents11Locked
Antiviral Agents11Locked
Cell cycle arrest11Locked
Chemosensitizer11Locked
Epidermal growth factor receptor (EGFR) inhibitor11Locked
Insulin-releasing11Locked
Interleukin-6 Downregulation11Locked
Leukotriene Antagonists11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
NF-kappaB Inhibitor11Locked
Prostaglandin Antagonists11Locked
Thromboxane (TXB) Inhibitors11Locked
Tumor Necrosis Factor (TNF) Alpha Enhancer11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked
Tumor Suppressor Protein p53 Upregulation11Locked

View the Evidence:
38 Abstracts with Andrographis Research

[+]

Andrographis extract was found to be effective and safe in reducing pain in individuals suffering from mild to moderate knee osteoarthritis.Apr 09, 2019

Pubmed Data : Phytother Res. 2019 Apr 10. Epub 2019 Apr 10. PMID: 30968986
Article Published Date : Apr 09, 2019
Study Type : Human Study
Additional Links
Substances : Andrographis
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics
[+]

Andrographis has a positive effect in the treatment of acute upper respiratory tract infections and also relieves the inflammatory symptoms of sinusitis.Oct 01, 2002

Pubmed Data : Phytomedicine. 2002 Oct;9(7):589-97. PMID: 12487322
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Andrographis
Diseases : Respiratory Tract Infections, Sinusitis
[+]

Andrographis has therapeutic activity against upper respiratory tract infections.Mar 01, 2010

Pubmed Data : Phytomedicine. 2010 Mar;17(3-4):178-85. Epub 2010 Jan 25. PMID: 20092985
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Andrographis
Diseases : Cold and Flu, Common Cold, Influenza, Upper Respiratory Infections
Additional Keywords : Plant Extracts
[+]

Andrographis reduces subjective and objective symptoms of rheumatoid arthritis. Aug 01, 2009

Pubmed Data : Clin Rheumatol. 2009 Aug;28(8):931-46. Epub 2009 Apr 29. PMID: 19408036
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Andrographis
Diseases : Rheumatoid Arthritis
[+]

Andrographis, Eleutherococcus (Siberian Ginseng), Schisandra and Glycyrrhiza (Licorice) is safe and efficacious in the management of Familial Mediterranean Fever.Aug 01, 2008

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):2022-5. PMID: 12809357
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Substances : Andrographis, Ginseng (Siberian), Licorice, Schisandra
Diseases : Familial Mediterranean Fever
[+]

A compound within Andrographis prevent diabetic nephropathy in an animal model. Aug 30, 2010

Pubmed Data : J Ethnopharmacol. 2010 Aug 30. Epub 2010 Aug 30. PMID: 20813180
Article Published Date : Aug 30, 2010
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Diabetic Nephropathy, Kidney Diseases, Nephropathy: Diabetic
Pharmacological Actions : Renoprotective
[+]

Andrographis and Hedyotis corymbosa in combination with curcumin have anti-malaria action.Feb 01, 2004

Pubmed Data : Phytother Res. 2004 Feb;18(2):164-8. PMID: 19216765
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Andrographis, Curcumin, Hedyotis corymbosa
Diseases : Malaria
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Andrographis does not appear to have any adverse effects on reproduction and fertility in male rats.Jul 01, 2009

Pubmed Data : Int J Toxicol. 2009 Jul-Aug;28(4):308-17. PMID: 19636073
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Andrographis
Additional Keywords : Plant Extracts
[+]

Andrographis has a prophylactic effect against Streptococcus agalactiae infection in Nile tilapia.May 01, 2009

Pubmed Data : J Biosci Bioeng. 2009 May;107(5):579-82. PMID: 19393561
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Andrographis has antioxidant, antioedema and analgesic activities.Jul 01, 2009

Pubmed Data : Phytother Res. 2009 Jul;23(7):958-64. PMID: 19142986
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Andrographis
Pharmacological Actions : Analgesics, Anti-edemic, Antioxidants
Additional Keywords : Plant Extracts
[+]

Andrographis has immunomodulatory activity. Jun 01, 2009

Pubmed Data : Planta Med. 2009 Jun;75(8):785-91. Epub 2009 Mar 4. PMID: 19263340
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
[+]

Andrographis may be more effective an anticancer agent than Doxorubicin in lymphoma. Dec 01, 2008

Pubmed Data : Mol Biol Rep. 2008 Dec;35(4):535-40. Epub 2007 Sep 5. PMID: 17805989
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Lymph Node Cancer, Lymphoma
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants
Additional Keywords : Drug: Doxorubicin, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Andrographis paniculata was shown to possess anti-tumor, anti-metastatic and immunomodulatory activities in esophageal cancer cell.Mar 11, 2019

Pubmed Data : Phytomedicine. 2019 Mar 12:152886. Epub 2019 Mar 12. PMID: 30910259
Article Published Date : Mar 11, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Esophageal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Immunomodulatory
[+]

Andrographolide, a compound found within andrographis, has anti-tumor activity in chemically-induced liver damage.Jun 01, 2005

Pubmed Data : Nutrition. 2005 Jun;21(6):756-61. PMID: 19679627
Article Published Date : Jun 01, 2005
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Chemically-Induced Liver Damage, Liver Cancer, Pesticide Toxicity
Pharmacological Actions : Hepatoprotective
[+]

Compounds found within Andrographis have potent anti-influenza activity against H1N1 and Avian Flu. Jan 01, 2009

Pubmed Data : Biol Pharm Bull. 2009;32(8):1385-1391. PMID: 19652378
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Avian Influenza, H1N1 Infection, Influenza A
Pharmacological Actions : Viral Hemagglutinin Inhibitor
Additional Keywords : Viral Hemmagglutinin Blocker
[+]

"The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma."Jun 01, 2011

Pubmed Data : Leuk Lymphoma. 2011 Jun ;52(6):1085-97. Epub 2011 Mar 21. PMID: 21417826
Article Published Date : Jun 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Andrographis, Feverfew
Diseases : Cancer Stem Cells, Multiple Myeloma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Cancer Stem Cells, Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Andrographis contains a compound known as andrographolide which exhibits anticancer and immunomodulatory activities.May 01, 2003

Pubmed Data : J Exp Ther Oncol. 2003 May-Jun;3(3):147-58. PMID: 14641821
Article Published Date : May 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancers: All
Pharmacological Actions : Cell cycle arrest, Immunomodulatory, Tumor Necrosis Factor (TNF) Alpha Enhancer
Additional Keywords : Plant Extracts
[+]

Andrographis contains a compound which enhances chemosensitivity of cancer cells to doxorubicin.May 01, 2010

Pubmed Data : Biochem Pharmacol. 2010 May 1;79(9):1242-50. Epub 2009 Dec 21. PMID: 20026083
Article Published Date : May 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancers: All
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies
[+]

Andrographis contains a compound which induces mitochondrial-mediated apoptosis in lymphoma cells.Aug 26, 2010

Pubmed Data : Clin Cancer Res. 2010 Aug 26. Epub 2010 Aug 26. PMID: 20798229
Article Published Date : Aug 26, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Follicular Lymphoma, Lymphoma, Non-Hodgkin's lymphoma: B Cell
Pharmacological Actions : Apoptotic
[+]

Andrographis contains a compound which inhibits human liver cancer cell growth.Oct 01, 2007

Pubmed Data : Planta Med. 2007 Oct;73(13):1397-401. Epub 2007 Oct 4. PMID: 17918040
Article Published Date : Oct 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Liver Cancer
Additional Keywords : Plant Extracts
[+]

Andrographis contains a compound which inhibits migration and invasion in human non-small lung cancer cells.Apr 25, 2010

Pubmed Data : Eur J Pharmacol. 2010 Apr 25;632(1-3):23-32. Epub 2010 Jan 25. PMID: 20097193
Article Published Date : Apr 25, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancer Metastasis, Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents
[+]

Andrographis contains a compound which may induce cancer cell death through epidermal factor receptor and transferrin receptor modulation.Apr 01, 2010

Pubmed Data : Br J Pharmacol. 2010 Apr;159(7):1497-510. Epub 2010 Feb 19. PMID: 20233216
Article Published Date : Apr 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Skin Cancer: Squamous Cell
Pharmacological Actions : Epidermal growth factor receptor (EGFR) inhibitor
[+]

Andrographis contains compounds which have antiprotozoal activity.Jan 01, 2009

Pubmed Data : Phytother Res. 2009 Jan;23(1):126-8. PMID: 18683849
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Protozoan Infections
Pharmacological Actions : Antiprotozoal Agents
Additional Keywords : Xanthones
[+]

Andrographis containsa compound which exhibits anti-invasive activity against colon cancer cells.Jun 10, 2010

Pubmed Data : Planta Med. 2010 Jun 10. Epub 2010 Jun 10. PMID: 20539971
Article Published Date : Jun 10, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancer Metastasis, Colon Cancer
Pharmacological Actions : Anti-metastatic
[+]

Andrographis exhibits insulin-releasing cells in vitro.Apr 01, 2008

Pubmed Data : Acta Med Indones. 2008 Apr-Jun;40(2):63-8. PMID: 18560025
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
[+]

Andrographis has anti-inflammatory and anti-allergic activity.May 27, 2010

Pubmed Data : J Ethnopharmacol. 2010 May 27;129(2):203-7. Epub 2010 Mar 20. PMID: 20307638
Article Published Date : May 27, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Allergies, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Leukotriene Antagonists, Prostaglandin Antagonists, Thromboxane (TXB) Inhibitors
[+]

Andrographis inhibits cell cycle progression of human colorectal carcinoma cellsAug 11, 2008

Pubmed Data : Chem Biol Interact. 2008 Aug 11;174(3):201-10. Epub 2008 Jun 20. PMID: 18619950
Article Published Date : Aug 11, 2008
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Colon Cancer, Colorectal Cancer, Rectal Cancer
[+]

Andrographis inhibits the adhesion of gastric cancer cells, indicating it may have therapeutic value in gastric cancer treatment.Jul 01, 2007

Pubmed Data : Anticancer Res. 2007 Jul-Aug;27(4B):2439-47. PMID: 17695536
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Gastric Cancer
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Andrographis may have therapeutic value in the treatment of cancer.Sep 14, 2009

Pubmed Data : Evid Based Complement Alternat Med. 2009 Sep 14. Epub 2009 Sep 14. PMID: 19752167
Article Published Date : Sep 14, 2009
Study Type : Review
Additional Links
Substances : Andrographis
Diseases : Cancers: All
Pharmacological Actions : Anti-Angiogenic, Immunomodulatory
[+]

Andrographis may provide therapeutic activity in the treatment of Multiple Sclerosis. Jan 01, 2005

Pubmed Data : J Pharmacol Exp Ther. 2005 Jan;312(1):366-72. Epub 2004 Aug 26 PMID: 15331658
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Multiple Sclerosis
[+]

Andrographolide effectively inhibits Epstein-barr virus.Nov 01, 2008

Pubmed Data : Biol Pharm Bull. 2008 Nov;31(11):2018-23. PMID: 18981566
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Epstein-Barr Virus Infections
[+]

Andrographolide enhances 5-fluorouracil-induced programmed cell death in liver cancer cells. Apr 18, 2009

Pubmed Data : Cancer Lett. 2009 Apr 18;276(2):180-8. Epub 2008 Dec 20. PMID: 19097688
Article Published Date : Apr 18, 2009
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Andrographolide is cytotoxic to human liver cancer cells. Aug 01, 2011

Pubmed Data : Mol Carcinog. 2011 Aug ;50(8):580-91. Epub 2011 Feb 11. PMID: 21319226
Article Published Date : Aug 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Andrographis, Andrographolide
Diseases : Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
[+]

Andrographolide may inhibit human colorectal cancer migration and invasion. Aug 14, 2009

Pubmed Data : Chem Biol Interact. 2009 Aug 14;180(3):344-52. Epub 2009 May 6. PMID: 19426720
Article Published Date : Aug 14, 2009
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancer Metastasis, Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Andrographolide, a compounds in Andrographis, inhibits growth of acute promyelocytic leukaemia cells.Jan 01, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Jan;61(1):69-78. PMID: 19126299
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Promyelocytic leukemia
[+]

Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth.Aug 01, 2010

Pubmed Data : Genes Cancer. 2010 Aug 1;1(8):868-876. PMID: 21442031
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Prostate Cancer
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Safety confirmation: Andrographis paniculata.Aug 01, 2009

Pubmed Data : Food Chem Toxicol. 2009 Aug;47(8):1892-902. Epub 2009 May 15. PMID: 19447157
Article Published Date : Aug 01, 2009
Study Type : Review
Additional Links
Substances : Andrographis
Additional Keywords : Plant Extracts
[+]

This study illustrates the antiviral property of these Asian medicinal plants against the highly pathogenic avian H5N1 influenza virus.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2017 Sep ;10(9):871-876. Epub 2017 Sep 14. PMID: 29080615
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Andrographis, Guava, Gynostemma, Kaempferia parviflora, Turmeric
Diseases : H5N1 Infection, Influenza
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts

Copyright: sirfujiyama / 123RF Stock Photo

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