Andrographolide

Name	AC	CK
Inflammation	13	16
Breast Cancer	10	12
Lipopolysaccharide-Induced Toxicity	7	12
Coronavirus Infection	10	10
Cancers: All	8	8
Brain Inflammation	4	7
Lung Cancer	7	7
Sepsis	3	7
Alzheimer's Disease	4	6
Liver Cancer	6	6
Atherosclerosis	3	5
Breast Cancer: Triple Negative	4	5
Cardiovascular Diseases	3	5
Colorectal Cancer	4	5
Degenerative Disk Disease	2	5
Rheumatoid Arthritis	4	5
Cerebral Ischemia	2	4
Colon Cancer	3	4
Depression	2	4
Diabetic Nephropathy	2	4
Gastric Cancer	4	4
Lung Damage	2	4
Nonalcoholic fatty liver disease (NAFLD)	2	4
Osteoarthritis	2	4
Oxidative Stress	3	4
Pneumonia	2	4
Carcinoma: Non-Small-Cell Lung	3	3
Corneal Diseases	1	3
Eye Damage	1	3
Fibrosis	1	3
Kidney Damage	1	3
Klebsiella Infections	2	3
Lymphedema	1	3
Obesity	2	3
Sickle Cell Anemia	1	3
Stroke: Ischemic	1	3
Subarachnoid hemorrhage	1	3
Acetaminophen (Tylenol) Toxicity	1	2
Allodynia	1	2
Aluminum Toxicity	1	2
Brain Injury: Traumatic	1	2
Brain: Oxidative Stress	1	2
Cardiomyopathy	1	2
Cervical Cancer	2	2
Chemically-Induced Liver Damage	2	2
Chikungunya Virus	2	2
Cholesterol: Oxidation	1	2
Chronic Obstructive Pulmonary Disease	1	2
Cognitive Decline/Dysfunction	1	2
Colitis	1	2
Diabetes Mellitus: Type 1	1	2
Diabetes Mellitus: Type 2	1	2
Diabetes: Cognitive Dysfunction	1	2
Enterovirus 71	1	2
Hepatic Steatosis	1	2
Hepatitis C	2	2
Herpes Simplex Virus Type 1	1	2
High Fat Diet	1	2
Hypertension: Pulmonary	1	2
Hypoglycemia	1	2
Influenza	2	2
Influenza A	1	2
Insulin Resistance	1	2
Kidney Fibrosis	1	2
Liver Damage: Drug-Induced	1	2
Liver Disease	1	2
Lung Injury: Acute	1	2
Lung Injury: Smoke-Induced	1	2
Malaria	1	2
Memory Disorders	1	2
Mycobacterium Tuberculosis	2	2
Neuropathic Pain	1	2
Pain: Post-operative	1	2
Pancreatic Cancer	2	2
Pesticide Toxicity	1	2
Pseudomonas aeruginosa	2	2
Psoriasis	1	2
Schizophrenia	1	2
Sinusoidal obstruction syndrome	1	2
Spinal Cord Injuries	1	2
Staphylococcus aureus infection	2	2
Stroke	1	2
Ultraviolet Radiation Induced Damage	1	2
Wound Healing	1	2
Acute Myeloid Leukemia	1	1
Acute Respiratory Distress Syndrome	1	1
Aneurysm: Aortic	1	1
Arthritis	1	1
Bacillus subtilis infections	1	1
Bladder Cancer	1	1
Burkitt Lymphoma	1	1
Cancer Metastasis	1	1
Chemotherapy-Induced Toxicity: Arsenic Trioxide	1	1
Chemotherapy-Induced Toxicity: Cisplatin	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Coronavirus Disease (Covid-19)	1	1
Degenerative Joint Disease	1	1
Dengue	1	1
Endometriosis	1	1
Enterovirus	1	1
Epstein-Barr Virus Infections	1	1
Escherichia coli Infections	1	1
Giardiasis	1	1
Glioblastoma	1	1
Gulf War Syndrome	1	1
Hepatoma	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Hypertension	1	1
Kidney Cancer	1	1
Leishmaniasis	1	1
Leukemia	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Liver Cirrhosis	1	1
Liver Damage	1	1
Melanoma	1	1
Metabolic Syndrome X	1	1
Methicillin-resistant Staphylococcus aureus	1	1
Multiple Myeloma	1	1
Musculoskeletal Diseases	1	1
Mycobacterium Infections	1	1
Myocardial Ischemia	1	1
Nasopharyngeal Cancer	1	1
Oral Cancer	1	1
Ovarian Cancer	1	1
Paraquat Toxicity	1	1
Parasitic Diseases	1	1
Promyelocytic leukemia	1	1
Prostate Cancer	1	1
Protozoan Infections	1	1
Pulmonary Fibrosis: Bleomycin-Induced	1	1
Respiratory Syncytial Virus Infections	1	1
Salmonella Infections	1	1
Smoking	1	1
Squamous cell carcinoma	1	1
Streptococcus Infections	1	1
Thyroid Cancer	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Anti-Inflammatory Agents	58	83
Antioxidants	24	37
Apoptotic	32	34
NF-kappaB Inhibitor	21	33
Antiproliferative	26	31
Neuroprotective Agents	13	25
Tumor Necrosis Factor (TNF) Alpha Inhibitor	17	24
Nrf2 activation	11	21
Antiviral Agents	18	20
Anti-Apoptotic	10	18
Heme oxygenase-1 up-regulation	10	18
Immunomodulatory	11	16
Interleukin-1 beta downregulation	9	14
Interleukin-6 Downregulation	9	13
Hepatoprotective	8	12
Interferon Gamma Reducer	4	8
Renoprotective	4	8
Anti-Bacterial Agents	6	7
Anti-metastatic	7	7
Anti-Fibrotic	3	6
Interleukin-10 upregulation	3	6
Cardioprotective	3	5
Cell cycle arrest	5	5
Chemosensitizer	4	5
Chemotherapeutic	5	5
Antidepressive Agents	2	4
Antineoplastic Agents	4	4
Hypoglycemic Agents	2	4
MicroRNA modulator	3	4
Autophagy Up-regulation	2	3
Malondialdehyde Down-regulation	2	3
Osteoprotective	2	3
Tumor Suppressor Protein p53 Upregulation	3	3
Wnt/β-catenin signaling pathway modulation	2	3
Analgesics	1	2
Angiogenesis Inhibitors	2	2
Antihypertensive Agents	2	2
Antinoceceptive	1	2
Antioxidant	1	2
Antiparasitic Agents	2	2
Brain-derived neurotrophic factor modulator	1	2
Chemoprotective Agents	2	2
Cyclin D1 Down-Regulation	1	2
Cyclooxygenase 2 Inhibitors	2	2
Enzyme Inhibitors	2	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Insulin Sensitizers	1	2
Insulin-releasing	1	2
Interleukin-2 Downregulation	1	2
Interleukin-4 upregulation	1	2
Photoprotective	1	2
Postaglandin PGE2 downregulation	1	2
Radiosensitizer	2	2
STAT3 Inhibitor	1	2
Superoxide Dismutase Up-regulation	1	2
Anticholesteremic Agents	1	1
Antimutagenic Agents	1	1
Antioxidant Effects	1	1
Antiprotozoal Agents	1	1
Autophagy Inhibitors	1	1
Bcl-2 protein down-regulation	1	1
Chemopreventive	1	1
Chondroprotective	1	1
Hypolipidemic	1	1
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	1
Leishmanicidal	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
Vascular Endothelial Growth Factor A Inhibitor	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
Vasoprotective	1	1

Andrographolide ameliorates diabetic cardiomyopathy.Dec 31, 2017

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Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:9086747. Epub 2018 Jun 25. PMID: 30046380

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Andrographolide

Diseases : Cardiomyopathy

Pharmacological Actions : Antioxidants, Apoptotic, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation

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Andrographolide ameliorates hepatic steatosis.Sep 16, 2022

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Pharmacological Actions : Analgesics

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Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C.Nov 30, 2020

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Pubmed Data : J Pharmacol Sci. 2020 Dec ;144(4):189-196. Epub 2020 Aug 26. PMID: 33070837

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Pubmed Data : J Ethnopharmacol. 2021 Aug 3 ;280:114487. Epub 2021 Aug 3. PMID: 34352330

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Pubmed Data : Int J Biol Macromol. 2012 Dec ;51(5):738-42. Epub 2012 Jul 2. PMID: 22766034

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Pubmed Data : J Pharmacol Sci. 2021 Sep ;147(1):9-17. Epub 2021 May 24. PMID: 34294378

Article Published Date : Aug 31, 2021

Study Type : Animal Study

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Substances : Andrographolide

Diseases : Brain: Oxidative Stress, Schizophrenia

Pharmacological Actions : Antioxidants, Nrf2 activation

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This review aims to summarize an overview on the neuroprotective effects of andrographolide and exemplifies the essential mechanisms involved.Jul 26, 2017

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Pubmed Data : Int J Mol Sci. 2017 Jul 27 ;18(8). Epub 2017 Jul 27. PMID: 28749412

Article Published Date : Jul 26, 2017

Study Type : Animal Study, In Vitro Study

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Substances : Andrographolide

Diseases : Stroke

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation

Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Antioxidants, stroke

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Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.Aug 31, 2019

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Pubmed Data : J Nat Med. 2024 Jan ;78(1):123-145. Epub 2023 Oct 12. PMID: 37821666

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

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Substances : Andrographolide

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor

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Andrographolide attenuates RSV-induced inflammation by suppressing apoptosis and promoting pyroptosis after respiratory syncytial virus infection.Nov 06, 2023

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Pubmed Data : Ann Transl Med. 2021 May ;9(9):764. PMID: 34268377

Article Published Date : Apr 30, 2021

Study Type : In Vitro Study

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Substances : Andrographolide

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Chemoprotective Agents

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Andrographolide could bind with TNF and NFkB1 proteins, block TNF-induced cytokine storm in COVID-19 patients.Dec 31, 2020

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Pubmed Data : Drug Des Devel Ther. 2017 ;11:3333-3341. Epub 2017 Nov 23. PMID: 29200829

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

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Substances : Andrographolide

Diseases : Colorectal Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

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Andrographolide enhances cisplatin-mediated anticancer effects in lung cancer cells.Jul 06, 2017

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Pubmed Data : Anticancer Drugs. 2017 Jul 7. Epub 2017 Jul 7. PMID: 28692436

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Pubmed Data : Pharmazie. 2018 10 1 ;73(10):594-597. PMID: 30223924

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

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Andrographolide inhibits proliferation and induces cell cycle arrest and apoptosis in human melanoma cells.Mar 31, 2018

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Pubmed Data : Mol Carcinog. 2011 Aug ;50(8):580-91. Epub 2011 Feb 11. PMID: 21319226

Article Published Date : Aug 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Andrographis, Andrographolide

Diseases : Liver Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic

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Andrographolide is worth to be clinically further studied in ARDS treatment.Dec 31, 2021

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Pubmed Data : Intensive Care Res. 2022 ;2(3-4):61-70. Epub 2022 Jul 13. PMID: 36523372

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Acute Respiratory Distress Syndrome

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

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Andrographolide may be effective in lowering cytokine storm and treating severe symptoms.Jul 16, 2022

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Pubmed Data : Molecules. 2022 Jul 17 ;27(14). Epub 2022 Jul 17. PMID: 35889428

Article Published Date : Jul 16, 2022

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Cytokine Modulation, Cytokine Storm

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Andrographolide may offer a pharmacological therapy to slow disease progression in patients with small aneurysms.Dec 31, 2015

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Pubmed Data : Int J Nanomedicine. 2010 Dec 9 ;5:1113-21. Epub 2010 Dec 9. PMID: 21270962

Article Published Date : Dec 08, 2010

Study Type : In Vitro Study

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Substances : Andrographolide

Diseases : Leishmaniasis

Pharmacological Actions : Leishmanicidal

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Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway.Dec 31, 2017

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Andrographolide sulfonate is a promising treatment to combat methicillin-resistant Staphylococcus aureus.Dec 31, 2020

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Pubmed Data : Front Pharmacol. 2021 ;12:720685. Epub 2021 Sep 16. PMID: 34603031

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Andrographolide

Diseases : Methicillin-resistant Staphylococcus aureus

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

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Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression.Mar 31, 2023

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Pubmed Data : Oncol Rep. 2023 Apr ;49(4). Epub 2023 Feb 24. PMID: 36825595

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Pubmed Data : Asian Pac J Trop Biomed. 2013 Aug ;3(8):604-10; discussion 609-10. PMID: 23905016

Article Published Date : Jul 31, 2013

Study Type : In Vitro Study

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Substances : Andrographis, Andrographolide

Diseases : Bacillus subtilis infections, Escherichia coli Infections, Klebsiella Infections, Mycobacterium Infections, Pseudomonas aeruginosa, Staphylococcus aureus infection, Streptococcus Infections

Pharmacological Actions : Anti-Bacterial Agents, Antioxidants

Additional Keywords : Plant Extracts

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Exploring the mechanism of andrographolide in the treatment of gastric cancer.Oct 31, 2022

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Pubmed Data : Hum Reprod Update. 2021 Feb 19 ;27(2):367-392. PMID: 33124671

Article Published Date : Feb 18, 2021

Study Type : Review

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Substances : Andrographolide, Apigenin, Carnosic Acid, Curcumin, Ginsenosides, Parthenolide, Puerarin, Quercetin, Resveratrol, Wogonin, Xanthohumol

Diseases : Endometriosis

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor Inhibitors

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Protective mechanism of andrographolide against carbon tetrachloride-induced acute liver injury in mice.Dec 31, 2010

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Pubmed Data : Biol Pharm Bull. 2011 ;34(11):1666-70. PMID: 22040877

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Chemically-Induced Liver Damage, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

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siRNA targeting Mcl-1 potentiates the anticancer activity of andrographolide nanosuspensions via apoptosis in breast cancer cells.Jun 02, 2022

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Pubmed Data : Cancers (Basel). 2020 Feb 7 ;12(2). Epub 2020 Feb 7. PMID: 32046125

Article Published Date : Feb 06, 2020

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Cervical Cancer

Pharmacological Actions : Apoptotic

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The present review supports that targeting chronic inflammation may have a broad application prospect for the prevention and treatment of cancer.May 31, 2017

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Pubmed Data : Sci China Life Sci. 2017 Jun ;60(6):601-616. Epub 2017 May 29. PMID: 28639101

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Pubmed Data : Phytomedicine. 2023 Jan ;109:154537. Epub 2023 Jan 5. PMID: 36610122

Article Published Date : Dec 31, 2022

Study Type : Review

Additional Links

Substances : Andrographolide

Diseases : Liver Cancer, Liver Cirrhosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

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These may indicate the application of andrographolide for therapeutic use in equine degenerative joint diseases.Dec 31, 2013

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Pubmed Data : Int Sch Res Notices. 2014 ;2014:464136. Epub 2014 Oct 29. PMID: 27379277

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Andrographolide

Diseases : Degenerative Joint Disease

Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor

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TMT-based quantitative proteomics reveals the targets of andrographolide on LPS-induced liver injury.Oct 09, 2023

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Pubmed Data : BMC Vet Res. 2023 Oct 10 ;19(1):199. Epub 2023 Oct 10. PMID: 37817228

Article Published Date : Oct 09, 2023

Study Type : In Vitro Study

Additional Links

Substances : Andrographis, Andrographolide

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Hepatoprotective

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Andrographolide alleviated blood-brain barrier disruption, neuronal apoptosis, and oxidative stress in subarachnoid hemorrhage.Mar 18, 2022

Andrographolide attenuates sepsis-induced acute kidney injury.Feb 29, 2024

Andrographolide inhibits corneal fibroblast to myofibroblast differentiation in vitro.Jan 08, 2022

Andrographolide inhibits ER-positive breast cancer.Dec 31, 2021

Andrographolide inhibits static mechanical pressure-induced intervertebral disc degeneration.Dec 31, 2022

Andrographolide inhibits the proliferation and migration of vascular smooth muscle cells to prevent intimal hyperplasia.Nov 14, 2023

Andrographolide promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.Sep 02, 2024

Cerebroprotective potential of andrographolide nanoparticles.Jul 10, 2024

Investigating the potential use of andrographolide as a coadjuvant in sickle cell anemia therapy.Apr 18, 2022

Activity of 3,19-isopropylidinyl andrographolide against herpes simplex virus type 1.Dec 31, 2021

Andrographolide alleviates acute brain injury. Dec 31, 2017

Andrographolide alleviates paraquat-induced acute lung injury.Dec 31, 2022

Andrographolide ameliorates diabetic cardiomyopathy.Dec 31, 2017

Andrographolide ameliorates hepatic steatosis.Sep 16, 2022

Andrographolide ameliorates neuroinflammation in APP/PS1 transgenic mice .Jun 30, 2021

Andrographolide ameliorates rheumatoid arthritis.Oct 10, 2019

Andrographolide attenuated MCT-induced HSOS via regulating NRF2-initiated mitochondrial biogenesis and antioxidant response.Oct 10, 2023

Andrographolide attenuates established pulmonary hypertension.Jan 29, 2021

Andrographolide attenuates inflammation due to intra-abdominal sepsis.Dec 31, 2022

Andrographolide attenuates NLRP3 inflammasome activation and airway inflammation in exacerbation of chronic obstructive pulmonary disease.Dec 31, 2023

Andrographolide attenuates oxidized LDL-induced activation of the NLRP3 inflammasome in bone marrow-derived macrophages.Nov 03, 2023

Andrographolide contributes to spinal cord injury repair.Dec 31, 2021

Andrographolide exerted anti-inflammatory effects thereby reducing sex hormone synthesis in LPS-induced female rats.Dec 31, 2021

Andrographolide exerts significant antidepressant-like effects.Dec 31, 2018

Andrographolide exhibits antinociceptive effects in neuropathic pain.Jun 11, 2024

Andrographolide influences IDD cell autophagy and oxidative stress under mechanical pressure.Jun 04, 2024

Andrographolide inhibits influenza A virus-induced inflammation in a murine model through NF-κB and JAK-STAT signaling pathway.Jan 11, 2017

Andrographolide inhibits oxidized LDL-induced cholesterol accumulation and foam cell formation in macrophages.Dec 31, 2017

Andrographolide inhibits the activation of spinal microglia and ameliorates mechanical allodynia.Nov 17, 2023

Andrographolide may have therapeutic value in the treatment of stroke.Sep 30, 2010

Andrographolide prevented type 1 diabetes by maintaining Th1/Th2/Th17 homeostasis.Jul 31, 2013

Andrographolide prevents high glucose-induced renal tubular cell damage.Jul 08, 2021

Andrographolide prevents high-fat diet-induced obesity.Oct 31, 2014

Andrographolide protects acute ultraviolet-B radiation-induced photodamages.Dec 09, 2022

Andrographolide protects against cigarette smoke-induced lung inflammation through activation of heme oxygenase-1.Apr 30, 2013

Andrographolide relieves post-operative wound pain but affects local angiogenesis.Dec 18, 2022

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C.Nov 30, 2020

Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response.May 31, 2014

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury.Apr 30, 2016

Andrographolide sulfonate attenuates acute lung injury.Dec 31, 2017

Andrographolide sulfonate improves Alzheimer-associated phenotypes and mitochondrial dysfunction in APP/PS1 transgenic mice.Dec 31, 2017

Andrographolide sulfonate reduces mortality in Enterovirus 71 infected mice by modulating immunity.Jan 31, 2018

Andrographolide suppresses osteoarthritis progression by regulating circ_Rapgef1/miR-383-3p/NLRP3 signaling axis.Mar 31, 2022

Andrographolide suppresses the malignancy of triple-negative breast cancer.Oct 26, 2022

Andrographolide, a novel inducer of apelin gene expression.Aug 02, 2021

Anti-malarial and cytokine-modulating effects of andrographolide in a murine model of malarial infection.Aug 31, 2019

Antidepressant evaluation of Andrographis paniculata Nees extract and andrographolide.Aug 31, 2023

Dual actions of gallic acid and andrographolide trigger AdipoR1 to stimulate insulin secretion in a streptozotocin-induced diabetes rat model.Dec 31, 2022

Effect of two andrographolide derivatives on cellular and rodent models of non-alcoholic fatty liver disease.Oct 31, 2017

Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism.Dec 31, 2021

Identification of Andrographolide as a novel FABP4 inhibitor for osteoarthritis treatment.Aug 31, 2023

Inhibition of NLRP3 inflammasome activation in myeloid-derived suppressor cells by andrographolide sulfonate contributes to 5-FU sensitization.Aug 12, 2021

Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta-catenin signaling.May 25, 2022

Network pharmacology-based strategy to investigate pharmacological mechanisms of Andrographolide for treatment of vascular cognitive impairment.Apr 05, 2022

Protective effect of andrographolide against STZ induced Alzheimer's disease in experimental rats: possible neuromodulation and Aβ (1-42) analysis/Jul 31, 2021

Protective effects of andrographolide against cerebral ischemia‑reperfusion injury in mice.Sep 30, 2021

Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with andrographolide.Nov 30, 2012

The potential anti-psoriatic effects of andrographolide.May 05, 2024

These findings collectively suggest that andrographolide holds the potential to counteract memory impairment instigated by aluminum toxicity.May 20, 2024

These results suggested that andrographolide improved oxidative stress and schizophrenia-like behaviors.Aug 31, 2021

This review aims to summarize an overview on the neuroprotective effects of andrographolide and exemplifies the essential mechanisms involved.Jul 26, 2017

Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.Aug 31, 2019

Water-soluble andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways.Nov 30, 2012

A comprehensive review on disposition kinetics and dosage of oral administration of Andrographis paniculata, an alternative herbal medicine, in co-treatment of coronavirus disease.Dec 31, 2021

Activity of andrographolide against chikungunya virus infection.Sep 17, 2015

Administration of andrographolideas an effective alternate safe compound to curtail and impede cervical cancer progression.May 25, 2024

An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide.Feb 06, 2015

Andrographis paniculata and andrographolide - a snapshot on recent advances in nano drug delivery systems against cancer.Feb 02, 2023

Andrographis paniculata downregulates proinflammatory cytokine production and augments cell mediated immune response in metastatic tumors.Dec 31, 2009

Andrographolide - A prospective remedy for chikungunya fever and viral arthritis.Aug 11, 2021

Andrographolide anti-proliferation and metastasis of hepatocellular carcinoma.Dec 31, 2023

Andrographolide attenuates RSV-induced inflammation by suppressing apoptosis and promoting pyroptosis after respiratory syncytial virus infection.Nov 06, 2023

Andrographolide

View the Evidence:
179 Abstracts with Andrographolide Research