Apples

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130 Diseases Researched for Apples
NameACCKFocus
Cardiovascular Diseases675Locked
Colorectal Cancer1065Locked
Breast Cancer1448Locked
Colon Cancer1337Locked
Diabetes Mellitus: Type 2433Locked
High Fat Diet1632Locked
Radiation-Induced Illness: Cesium-137 Exposure431Locked
Cancers: All628Locked
Hyperglycemia626Locked
Oxidative Stress1024Locked
Esophageal Cancer221Locked
Metabolic Diseases121Locked
Oral Cancer221Locked
Hypertension120Locked
Overweight 220Locked
Dysbiosis416Locked
Endothelial Dysfunction416Locked
Obesity816Locked
Alzheimer's Disease415Locked
Hair Loss413Locked
Helicobacter Pylori Infection313Locked
Atherosclerosis612Locked
Hepatic Steatosis612Locked
Hyperuricemia212Locked
Insulin Resistance612Locked
Alopecia211Locked
Athletic Performance110Locked
Breast Cancer: Triple Negative 710Locked
Diarrhea110Locked
Dyslipidemias110Locked
Hemodialysis110Locked
Joint Diseases110Locked
Libido: Low110Locked
Mortality: All-Cause110Locked
Peripheral Arterial Disease110Locked
Prediabetes110Locked
Schizophrenia110Locked
Skin Diseases: Photo-Aging110Locked
Stroke110Locked
Systemic Lupus Erythematosus110Locked
Ultraviolet Radiation Induced Damage110Locked
Inflammatory Bowel Diseases59Locked
Liver Cancer69Locked
Ulcerative Colitis48Locked
Chemically-Induced Liver Damage26Locked
Cholera26Locked
Cognitive Decline/Dysfunction36Locked
Colitis36Locked
Escherichia coli Infections66Locked
Hyperlipidemia36Locked
Aging35Locked
Aging: Brain 35Locked
Anti-gliadin Antibodies: Elevated15Locked
Cancer Metastasis25Locked
Food Allergies: Wheat15Locked
Staphylococcus aureus infection55Locked
Aluminum Toxicity 24Locked
Aspirin-Induced Toxicity 14Locked
Brain: Oxidative Stress24Locked
C-Reactive Protein24Locked
Candida Infection 24Locked
Colon Polyps14Locked
Colorectal Cancer: Prevention 14Locked
Hypertension: Pulmonary24Locked
Neurodegenerative Diseases34Locked
Periodontal Diseases34Locked
Vaccine-induced Toxicity 14Locked
Advanced Glycation End products (AGE)23Locked
Colon Cancer: Prevention23Locked
Gastrointestinal Inflammation23Locked
Inflammation23Locked
Listeria Infections33Locked
Nonalcoholic fatty liver disease (NAFLD)23Locked
Alcohol Toxicity 12Locked
Antibiotic Toxicity 12Locked
Brain Inflammation 12Locked
Brain Ischemia12Locked
Candida Albicans22Locked
Cardiovascular Disease: Prevention12Locked
Circadian Dysregulation12Locked
Clostridium Infections12Locked
Colorectal Tumors12Locked
Diabetic Complications22Locked
Drug-Induced Toxicity: Indomethacin12Locked
Fibrinogen: Elevated12Locked
Food Allergies12Locked
High Cholesterol12Locked
High Cholesterol: very low density lipoprotein (VLDL)12Locked
Hypoxia12Locked
Infertility: Male12Locked
Irritable Bowel Syndrome12Locked
Kidney Damage: Chemically-Induced12Locked
Liver Damage: Drug-Induced12Locked
Malabsorption Syndrome 12Locked
Mitochondrial Dysfunction 12Locked
Muscle Fatigue12Locked
Osteoarthritis12Locked
Osteoarthritis: Knee12Locked
Osteoporosis12Locked
Radiation Induced Illness12Locked
Radiation-Induced Illness: Americium12Locked
Radiation-Induced Illness: Plutonium 12Locked
Radiotherapy12Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)22Locked
Tongue Cancer12Locked
Triglycerides: Elevated12Locked
Tumors12Locked
Allergic Rhinitis11Locked
Allergies11Locked
Cancers: Multi-Drug Resistant11Locked
Chemotherapy and Radiation Toxicity11Locked
DNA damage11Locked
Denture Stomatitis11Locked
Diabetes: Cognitive Dysfunction11Locked
Endotoxemia11Locked
Enterococcus Infections11Locked
Hepatoma11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Hypercholesterolemia11Locked
Influenza A11Locked
Lipid Peroxidation11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Male Pattern Baldness11Locked
Porphyromonas gingivalis11Locked
Radiation Disaster Associated Toxicity11Locked
Salmonella Infections11Locked
Squamous cell carcinoma11Locked
Staphylococcal Infections11Locked
Stomach Cancer11Locked
Thyroid Cancer11Locked
79 Pharmacological Actions Researched for Apples
NameACCKFocus
Antioxidants50142Locked
Hypoglycemic Agents13101Locked
Anti-Inflammatory Agents2249Locked
Chemopreventive1440Locked
Gastrointestinal Agents1138Locked
Hypolipidemic935Locked
Anticholesteremic Agents332Locked
Hepatoprotective1531Locked
Antiproliferative 1726Locked
Cardioprotective426Locked
Radioprotective626Locked
Apoptotic1621Locked
Detoxifier321Locked
Detoxifier: Radionuclide Removal220Locked
Cyclooxygenase 2 Inhibitors517Locked
Neuroprotective Agents1017Locked
Anti-Bacterial Agents1114Locked
NF-kappaB Inhibitor914Locked
Anti-metastatic613Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor813Locked
Anti-Apoptotic612Locked
Cell cycle arrest912Locked
Antinoceceptive 110Locked
Aphrodisiac 110Locked
Lipoxygenase Inhibitors110Locked
Photoprotective110Locked
Uricosuric Agents110Locked
Tumor Suppressor Protein p53 Upregulation49Locked
Anticarcinogenic Agents58Locked
Anti-Allergic Agents37Locked
Interleukin-1 beta downregulation47Locked
Antimicrobial36Locked
Gastroprotective26Locked
Angiogenesis Inhibitors15Locked
Superoxide Dismutase Up-regulation35Locked
Vascular Endothelial Growth Factor Inhibitors15Locked
Anti-atherogenic24Locked
Catalase Up-Regulation24Locked
Chondroprotective24Locked
Enzyme Inhibitors34Locked
Interleukin-6 Downregulation34Locked
Renoprotective24Locked
Vasodilator Agents24Locked
Alpha-glucosidase inhibitor 33Locked
MicroRNA modulator23Locked
Prophylactic Agents23Locked
Alpha-amylase inhibitor22Locked
Antidiarrheals12Locked
Antihypertensive Agents12Locked
Appetite Depressants12Locked
Autophagy Up-regulation22Locked
Chelating Agents12Locked
Fertility Agents: Male12Locked
Immunomodulatory12Locked
Insulin Sensitizers12Locked
Interferon Gamma Reducer12Locked
Malondialdehyde Down-regulation12Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor22Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
Nrf2 activation22Locked
Osteoprotective 12Locked
P21 Activation22Locked
SIRT1 Activator12Locked
Acetylcholinesterase Inhibitor11Locked
Anti-Glycation Agents11Locked
Antifungal Agents11Locked
Antimutagenic Agents11Locked
Antiviral Agents11Locked
Caspase-3 Activation11Locked
Chemoprotective Agents11Locked
Chemosensitizer11Locked
Chemotherapeutic11Locked
Cyclin D1 Down-Regulation11Locked
Glutathione Upregulation 11Locked
Histone deacetylase inhibitor11Locked
Regenerative11Locked
Topoisomerase II Inhibitor11Locked
Viral Hemagglutinin Inhibitor11Locked
Wnt/β-catenin pathway down-regulation11Locked
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View the Evidence:
199 Abstracts with Apples Research

[+]
Pubmed Data : Curr Med Chem. 2023 Aug 22. Epub 2023 Aug 22. PMID: 37608660
Study Type : Meta Analysis, Review
Additional Links
Substances : Apple Cider Vinegar
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Cardiovasc Med. 2021 Sep 24 ;22(3):835-843. PMID: 34565081
Study Type : Meta Analysis, Review
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Cardioprotective
[+]
Pubmed Data : Public Health Nutr. 2016 Mar 22:1-15. Epub 2016 Mar 22. PMID: 27000627
Study Type : Meta Analysis
Additional Links
Substances : Apples
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Hypertension. 2016 Feb ;67(2):288-93. Epub 2015 Dec 7. PMID: 26644239
Study Type : Meta Analysis
Additional Links
Diseases : Hypertension
Additional Keywords : Risk Reduction
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2021 Jun 29 ;21(1):179. Epub 2021 Jun 29. PMID: 34187442
Study Type : Meta Analysis, Review
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]
Pubmed Data : Arzneimittelforschung. 2006;56(6):387-93. PMID: 16889120
Study Type : Human Study
Additional Links
Substances : Apple Pectin , Chamomile
Diseases : Diarrhea
[+]
Pubmed Data : Eur J Nutr. 2014 Dec ;53(8):1645-57. Epub 2014 Feb 16. PMID: 24531755
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents, Antioxidants
Additional Keywords : Fruit Juice, Natural Substance Synergy
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Aug 22 ;9(8). Epub 2017 Aug 22. PMID: 28829368
Study Type : Human Study
Additional Links
Therapeutic Actions : Exercise: Endurance
[+]
Pubmed Data : Am J Cardiol. 2018 Dec 3. Epub 2018 Dec 3. PMID: 30573159
Study Type : Human Study
Additional Links
Substances : Apple Polyphenols
[+]
Pubmed Data : Eur J Nutr. 2015 Aug 23. Epub 2015 Aug 23. PMID: 26298312
Study Type : Human Study
Additional Links
Substances : Apples, Green Tea
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : J Nutr Biochem. 2017 Jul 27 ;49:53-62. Epub 2017 Jul 27. PMID: 28886437
Study Type : Human Study
Additional Links
Pharmacological Actions : Hypoglycemic Agents
[+]
Pubmed Data : Arch Gynecol Obstet. 2014 Feb 12. Epub 2014 Feb 12. PMID: 24518938
Study Type : Human Study
Additional Links
Substances : Apples
Diseases : Libido: Low
Pharmacological Actions : Aphrodisiac
[+]
Pubmed Data : Nutr Res. 2018 Dec 29 ;64:56-63. Epub 2018 Dec 29. PMID: 30802723
Study Type : Human Study
Additional Links
Substances : Apples
Diseases : Hemodialysis
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Swiss Med Wkly. 2004 Jan 10;134(1-2):24-7. PMID: 14745664
Study Type : Human Study
Additional Links
Substances : Apple Pectin
Pharmacological Actions : Radioprotective
[+]
Pubmed Data : Mol Cell Biochem. 1990 Jun 1;95(1):21-30. PMID: 17314090
Study Type : Human Study
Additional Links
Substances : Apple Pectin
Pharmacological Actions : Detoxifier, Detoxifier: Radionuclide Removal
[+]
Pubmed Data : Swiss Med Wkly. 2004 Dec 18;134(49-50):725-9. PMID: 15635491
Study Type : Human Study
[+]
Pubmed Data : J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID: 19691323
Study Type : Human Study
Additional Links
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]
Pubmed Data : J Nutr Biochem. 2020 Jul 30:108466. Epub 2020 Jul 30. PMID: 32739411
Study Type : Human Study
Additional Links
Substances : Apple Polyphenols
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]
Pubmed Data : Mol Nutr Food Res. 2017 Jul 29. Epub 2017 Jul 29. PMID: 28755406
Study Type : Human Study
Additional Links
Substances : Apple Polyphenols
[+]
Pubmed Data : J Med Food. 2017 Sep 28. Epub 2017 Sep 28. PMID: 28956697
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Hair Loss
Additional Keywords : Hair Regeneration, Procyanidins
[+]
Pubmed Data : Clin Nutr ESPEN. 2019 Oct ;33:132-138. Epub 2019 Jul 9. PMID: 31451249
Study Type : Human Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]
Pubmed Data : Nord J Psychiatry. 2020 Aug 7:1-3. Epub 2020 Aug 7. PMID: 32762505
Study Type : Human Study
Additional Links
Substances : Apple Cider Vinegar
Diseases : Schizophrenia
Pharmacological Actions : Gastrointestinal Agents
[+]
Pubmed Data : Diabetes Res Clin Pract. 2017 May 2 ;129:43-51. Epub 2017 May 2. PMID: 28505543
Study Type : Human Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Hypoglycemic Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2014 Nov ;17(11):1204-13. Epub 2014 Oct 1. PMID: 25271471
Study Type : Human Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 13 ;12(4). Epub 2020 Apr 13. PMID: 32294883
Study Type : Human Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Photoprotective
[+]
Pubmed Data : Br J Nutr. 2015 Apr ;113 Suppl 2:S102-10. PMID: 26148912
Study Type : Human Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 2016 ;353:i2343. Epub 2016 May 11. PMID: 27170029
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Atherosclerosis. 2013 Mar ;227(1):147-52. Epub 2012 Dec 28. PMID: 23294925
Study Type : Human Study
Additional Links
Diseases : Stroke
Additional Keywords : Risk Reduction
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2021 Dec 14 ;13(12). Epub 2021 Dec 14. PMID: 34959435
Study Type : Human Study
Additional Links
Diseases : Alopecia
Additional Keywords : Natural Substance/Drug Synergy
[+]
Pubmed Data : Br J Nutr. 2016 Jan 20:1-8. Epub 2016 Jan 20. PMID: 26787402
Study Type : Human Study
Additional Links
Substances : Apples
Additional Keywords : Risk Reduction
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(2):1301-17. Epub 2015 Feb 16. PMID: 25690419
Study Type : Human Study
Additional Links
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
[+]
Pubmed Data : Ann Oncol. 2005 Nov;16(11):1841-4. Epub 2005 Aug 9. PMID: 16091428
Study Type : Human Study
Additional Links
Substances : Apples
Diseases : Cancers: All
[+]
Pubmed Data : Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID: 19476292
Study Type : Human Study
Additional Links
Substances : Apples
[+]
Pubmed Data : Nutrition. 2003 Mar;19(3):253-6. PMID: 12620529
Study Type : Human Study
Additional Links
Substances : Apples, Fruit: All, Pear
Diseases : Overweight
[+]
Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):262-71. Epub 2009 Jan 20. PMID: 19926998
Study Type : Human Study
Additional Links
Substances : Apples
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Br J Nutr. 2015 May 28 ;113(10):1531-8. Epub 2015 Apr 13. PMID: 25865751
Study Type : Human Study
Additional Links
Substances : Apple Pectin , Quercetin
Pharmacological Actions : Antioxidants
Additional Keywords : Dose Response
[+]
Pubmed Data : Nutr Cancer. 1996;25(3):297-304. PMID: 8771572
Study Type : Human Study
Additional Links
Pharmacological Actions : Chemopreventive
[+]
Pubmed Data : J Agric Food Chem. 2017 Feb 13. Epub 2017 Feb 13. PMID: 28190352
Study Type : Human In Vitro
Additional Links
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Plant Extracts
[+]
Pubmed Data : J Agric Food Chem. 2016 Sep 14 ;64(36):6826-37. Epub 2016 Sep 2. PMID: 27538679
Study Type : Animal Study, Human In Vitro
[+]
Pubmed Data : Mol Nutr Food Res. 2015 Mar ;59(3):401-12. Epub 2015 Jan 22. PMID: 25546248
Study Type : Human In Vitro
[+]
Pubmed Data : Altern Ther Health Med. 2017 Nov 7. Epub 2017 Nov 7. PMID: 29112940
Study Type : Human: Case Report
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antimicrobial
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:946161. Epub 2022 Sep 5. PMID: 36133807
Study Type : Animal Study, In Vitro Study
[+]
Pubmed Data : Nutrients. 2020 Aug 19 ;12(9). Epub 2020 Aug 19. PMID: 32825073
Study Type : Animal Study
[+]
Pubmed Data : Radiats Biol Radioecol. 1998 Jan-Feb;38(1):35-41. PMID: 9606404
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Prev Res (Phila). 2011 Jun ;4(6):907-15. Epub 2011 Mar 7. PMID: 21383028
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antioxidants, Chemopreventive
Additional Keywords : Dietary Concentrations
[+]
Pubmed Data : J Agric Food Chem. 2008 May 28;56(10):3574-81. Epub 2008 Apr 23. PMID: 18433105
Study Type : Animal Study
Additional Links
Substances : Apple Pectin
[+]
Pubmed Data : Wiad Lek. 2017;70(2):200-204. PMID: 28511159
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : J Agric Food Chem. 2016 Nov 23 ;64(46):8857-8865. Epub 2016 Nov 10. PMID: 27792335
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Additional Keywords : Procyanidins
[+]
Pubmed Data : Atherosclerosis. 2017 Jan 27 ;258:56-64. Epub 2017 Jan 27. PMID: 28196336
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]
Pubmed Data : Can J Physiol Pharmacol. 2014 Feb ;92(2):109-16. Epub 2014 Jan 29. PMID: 24502633
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Hepatoprotective
Problem Substances : Aluminum Chloride
[+]
Pubmed Data : Clin Exp Hypertens. 2017 Nov 6:1-8. Epub 2017 Nov 6. PMID: 29106302
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]
Pubmed Data : J Agric Food Chem. 2003 Sep 10;51(19):5780-5. PMID: 12952433
Study Type : Animal Study
Additional Links
Substances : Apples, Pear
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]
Pubmed Data : J Med Food. 2017 Nov 1. Epub 2017 Nov 1. PMID: 29091513
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antioxidants
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : Biosci Biotechnol Biochem. 2007 Sep;71(9):2124-9. Epub 2007 Sep 7. PMID: 17827702
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Diseases : Tumors
Additional Keywords : Alpha-Glycan
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microsc Ultrastruct. 2020 Jul-Sep;8(3):126-131. Epub 2020 Sep 10. PMID: 33282688
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Mercury
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabol Open. 2020 Dec ;8:100063. Epub 2020 Sep 30. PMID: 33103102
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Renoprotective
[+]
Pubmed Data : J Membr Biol. 2014 Aug ;247(8):667-73. Epub 2014 Jun 4. PMID: 24894721
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Additional Keywords : Increased Bioavailability
[+]
Pubmed Data : Drug Dev Res. 2021 Jun 28. Epub 2021 Jun 28. PMID: 34184291
Study Type : Animal Study, In Vitro Study
[+]
Pubmed Data : Int J Vitam Nutr Res. 2019 May 29:1-11. Epub 2019 May 29. PMID: 31140380
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Diseases : Hyperglycemia
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]
Pubmed Data :  2011 Jun 22;59(12):6638-44. doi: 10.1021/jf104912h. Epub 2011 May 18.  PMID: 21561165
Study Type : Animal Study
[+]
Pubmed Data : Toxicol Mech Methods. 2015 Jun 10:1-6. Epub 2015 Jun 10. PMID: 26062009
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Tongue Cancer
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Phytother Res. 2014 Jul 28. Epub 2014 Jul 28. PMID: 25069887
Study Type : Animal Study
Additional Links
Pharmacological Actions : Gastroprotective
Additional Keywords : Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Apr 5 ;17(1):200. Epub 2017 Apr 5. PMID: 28381226
Study Type : Animal Study
Additional Links
Substances : Apple, Apple Polyphenols
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12. PMID: 18558693
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 19804641
Study Type : Animal Study
Additional Links
Substances : Apples
[+]
Pubmed Data : Ann Clin Psychiatry. 2009 Jul-Sep;21(3):148-61. PMID: 16340085
Study Type : Animal Study
Additional Links
Substances : Apples
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Carcinogenesis. 2000 Aug;21(8):1461-7. PMID: 20652274
Study Type : Animal Study
Additional Links
Substances : Apples, Polyphenols
Pharmacological Actions : Antioxidants, Chemopreventive
[+]
Pubmed Data : Phytochemistry. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20022617
Study Type : Animal Study
Additional Links
Substances : Apples
Pharmacological Actions : Anti-Inflammatory Agents, Vasodilator Agents
[+]
Pubmed Data : Exp Anim. 2000 Oct;49(4):305-7. PMID: 11109558
Study Type : Transgenic Animal Study
[+]
Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 10834105
Study Type : Animal Study
Additional Links
[+]
Pubmed Data : J Exp Clin Cancer Res. 1997 Mar;16(1):33-8. PMID: 9148858
Study Type : Animal Study
Additional Links
Substances : Apple Pectin
Diseases : Colon Cancer
Additional Keywords : Bacteriostatic
[+]
Pubmed Data : Cancer Sci. 2009 May 12. PMID: 19292474
Study Type : Animal Study
Additional Links
Substances : Apple Pectin
[+]
Pubmed Data : Food Funct. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28239698
Study Type : Animal Study
[+]
Pubmed Data : Food Funct. 2023 Jul 17 ;14(14):6678-6689. Epub 2023 Jul 17. PMID: 37403576
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Problem Substances : Antibiotics
[+]
Pubmed Data : J Nutr Biochem. 2018 Mar 21 ;57:56-66. Epub 2018 Mar 21. PMID: 29674247
Study Type : Animal Study
[+]
Pubmed Data : J Agric Food Chem. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31608624
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Hepatoprotective, MicroRNA modulator
[+]
Pubmed Data : J Agric Food Chem. 2023 Oct 25 ;71(42):15506-15521. Epub 2023 Oct 12. PMID: 37824601
Study Type : Animal Study
[+]
Pubmed Data : Food Funct. 2024 Feb 26. Epub 2024 Feb 26. PMID: 38406886
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Depression
Additional Keywords : Gut-brain Axis
[+]
Pubmed Data : J Agric Food Chem. 2021 Jun 23 ;69(24):6829-6841. Epub 2021 Jun 14. PMID: 34124904
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective
[+]
Pubmed Data : Food Funct. 2022 Feb 17. Epub 2022 Feb 17. PMID: 35174840
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Gastrointestinal Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2022 Oct 30 ;12(11). Epub 2022 Oct 30. PMID: 36355125
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Gastrointestinal Agents
[+]
Pubmed Data : Neurotoxicology. 2014 Dec ;45:111-20. Epub 2014 Oct 17. PMID: 25445564
Study Type : Animal Study
Additional Links
Pharmacological Actions : Chelating Agents, Neuroprotective Agents
Additional Keywords : Chelation, Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2016 ;13:32. Epub 2016 Apr 30. PMID: 27141227
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Insulin Sensitizers
[+]
Pubmed Data : Vaccine. 2009 Jul 30;27(35):4808-17. Epub 2009 Jun 17. PMID: 19539583
Study Type : Animal Study
Additional Links
Additional Keywords : Drug Side Effect Attenuation
[+]
Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:937-944. Epub 2018 Aug 23. PMID: 30257406
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]
Pubmed Data : Chem Biol Interact. 2016 Aug 24. Epub 2016 Aug 24. PMID: 27567545
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Res Commun. 2022 May 7 ;614:120-124. Epub 2022 May 7. PMID: 35580540
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
[+]
Pubmed Data : Dig Liver Dis. 2012 Feb 28. Epub 2012 Feb 28. PMID: 22381211
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Colitis
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Nov 5 ;10(11). Epub 2021 Nov 5. PMID: 34828992
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]
Pubmed Data : Phytother Res. 2020 Nov 20. Epub 2020 Nov 20. PMID: 33215776
Study Type : Animal Study
[+]
Pubmed Data : J Agric Food Chem. 2021 Dec 22. Epub 2021 Dec 22. PMID: 34935369
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : J Nutr Biochem. 2019 Nov 23 ;77:108299. Epub 2019 Nov 23. PMID: 31841959
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : J Med Food. 2017 Nov ;20(11):1113-1120. PMID: 29120271
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]
Pubmed Data : Nutr Cancer. 2015 ;67(1):177-90. Epub 2014 Nov 20. PMID: 25412264
Study Type : Animal Study
Additional Links
Substances : Apples
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Int J Biol Macromol. 2017 Feb 23. Epub 2017 Feb 23. PMID: 28238909
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 May 8 ;8(1):7229. Epub 2018 May 8. PMID: 29739985
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective
[+]
Pubmed Data : Int Immunopharmacol. 2008 Dec 20;8(13-14):1802-7. Epub 2008 Sep 29. PMID: 18824249
Study Type : Animal Study
Additional Links
Substances : Apples
Additional Keywords : Proanthocyanidins
[+]
Pubmed Data : J Agric Food Chem. 2012 Sep 19 ;60(37):9430-6. Epub 2012 Sep 6. PMID: 22924395
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apples
Additional Keywords : Dose Response
[+]
Pubmed Data : Int J Cancer. 2008 Jun 15;122(12):2647-55. PMID: 18351577
Study Type : Animal Study
Additional Links
Diseases : Colon Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Epigenetic Modification
[+]
Pubmed Data : J Altern Complement Med. 2010 Sep;16(9):973-8. PMID: 15769178
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Breast Cancer
Pharmacological Actions : Antioxidants, Chemopreventive
[+]
Pubmed Data : Br J Nutr. 2009 Dec;102(11):1620-8. Epub 2009 Jul 22. PMID: 19622193
Study Type : Transgenic Animal Study
[+]
Pubmed Data : Andrologia. 2018 Oct ;50(8):e13065. Epub 2018 Jun 19. PMID: 29923211
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2020 ;2020:9284987. Epub 2020 Jul 10. PMID: 32766316
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]
Pubmed Data : PLoS One. 2015;10(7):e0134303. Epub 2015 Jul 29. PMID: 26222548
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Muscle Fatigue
[+]
Pubmed Data : J Sci Food Agric. 2020 Jan 9. Epub 2020 Jan 9. PMID: 31916584
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : Plant Foods Hum Nutr. 2018 Jan 31. Epub 2018 Jan 31. PMID: 29388158
Study Type : Animal Study
Additional Links
Pharmacological Actions : Gastrointestinal Agents
[+]
Pubmed Data : Int J Mol Med. 2010 Oct;26(4):447-55. PMID: 19158432
Study Type : Animal Study
Additional Links
Substances : Apples
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : FEBS Lett. 2005 Aug 15;579(20):4485-91. PMID: 16081068
Study Type : Animal Study
Additional Links
Diseases : Food Allergies
Additional Keywords : Proanthocyanidins
[+]
Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2019 May 28 ;35(3):209-214. PMID: 31257800
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
[+]
Pubmed Data : J Agric Food Chem. 2009 Jan 14;57(1):297-304. PMID: 19072049
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Breast Cancer
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Int J Biol Macromol. 2023 Dec 1 ;252:126233. Epub 2023 Aug 12. PMID: 37573904
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis
Pharmacological Actions : Gastrointestinal Agents
[+]
Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:637-644. Epub 2016 Sep 30. PMID: 27697635
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple Pectin
Diseases : Breast Cancer
[+]
Pubmed Data : Food Funct. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26741951
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Radiotherapy
Pharmacological Actions : Immunomodulatory, Radioprotective
[+]
Pubmed Data : Mol Nutr Food Res. 2008 Apr;52(4):400-7. PMID: 18214852
Study Type : Animal Study
Additional Links
Substances : Apples, Grape
Diseases : Atherosclerosis
Pharmacological Actions : Cardioprotective
[+]
Pubmed Data : J Agric Food Chem. 2023 Nov 1 ;71(43):16043-16056. Epub 2023 Oct 19. PMID: 37856155
Study Type : Animal Study
Additional Links
Substances : Apple Pectin
Pharmacological Actions : Gastrointestinal Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiol Immunol. 2002 ;46(4):249-55. PMID: 12061627
Study Type : Animal Study
Additional Links
Diseases : Cholera
Pharmacological Actions : Antidiarrheals, Antimicrobial, Enzyme Inhibitors
Additional Keywords : Dose Response, Plant Extracts
[+]
Pubmed Data : J Nutr. 2016 Apr 6. Epub 2016 Apr 6. PMID: 27052533
Study Type : Animal Study
Additional Links
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Pharm Biol. 2016 Sep 5:1-10. Epub 2016 Sep 5. PMID: 27595296
Study Type : Animal Study
Additional Links
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : J Agric Food Chem. 2022 Mar 1. Epub 2022 Mar 1. PMID: 35227062
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]
Pubmed Data : J Agric Food Chem. 2023 Dec 20 ;71(50):20011-20033. Epub 2023 Dec 6. PMID: 38055797
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]
Pubmed Data : Planta Med. 2010 Aug 17. Epub 2010 Aug 17. PMID: 20717869
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Aging
[+]
Pubmed Data : Chem Biol Interact. 2020 Apr 28 ;326:109113. Epub 2020 Apr 28. PMID: 32360496
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]
Pubmed Data : Food Funct. 2022 Jul 5. Epub 2022 Jul 5. PMID: 35788787
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Osteoprotective
[+]
Pubmed Data : Phytother Res. 2009 Dec 2. Epub 2009 Dec 2. PMID: 19957242
Study Type : Animal Study
Additional Links
Pharmacological Actions : Anti-Bacterial Agents
[+]
Pubmed Data : Ann Cardiol Angeiol (Paris). 2016 Jun ;65(3):208-13. Epub 2016 May 18. PMID: 27209492
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Additional Keywords : Anti-Obesity Agents, Risk Reduction
[+]
Pubmed Data : J Agric Food Chem. 2022 May 11 ;70(18):5579-5594. Epub 2022 Apr 29. PMID: 35485931
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
[+]
Pubmed Data : J Alzheimers Dis. 2006 Aug;9(3):287-91. PMID: 16914839
Study Type : Animal Study
Additional Links
Substances : Apples
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : J Am Coll Nutr. 2021 Jul 29:1-10. Epub 2021 Jul 29. PMID: 34323669
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Clin Sci (Lond). 2016 Sep 14. Epub 2016 Sep 14. PMID: 27630205
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]
Pubmed Data : Hum Exp Toxicol. 2016 Jan 25. Epub 2016 Jan 25. PMID: 26811344
Study Type : Animal Study
Additional Links
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective
Additional Keywords : Dose Response
[+]
Pubmed Data : Biomed Pharmacother. 2016 Oct ;83:1233-1238. Epub 2016 Aug 23. PMID: 27565845
Study Type : Animal Study
Additional Links
Substances : Apple Pectin
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]
Pubmed Data : Pharmaceuticals (Basel). 2021 Oct 29 ;14(11). Epub 2021 Oct 29. PMID: 34832888
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(8):7085-105. Epub 2015 Aug 24. PMID: 26305254
Study Type : Animal Study, In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jan 14 ;11(1). Epub 2019 Jan 14. PMID: 30646510
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
[+]
Pubmed Data : Complement Ther Med. 2020 Jun ;51:102425. Epub 2020 May 17. PMID: 32507438
Study Type : Review
[+]
Pubmed Data : J Food Biochem. 2020 Oct 20:e13504. Epub 2020 Oct 20. PMID: 33084094
Study Type : In Vitro Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]
Pubmed Data : Nutr Cancer. 2014 Sep 25:1-10. Epub 2014 Sep 25. PMID: 25256427
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Jan 14 ;14(1). Epub 2021 Jan 14. PMID: 33466604
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Sep 28 ;10(1):15921. Epub 2020 Sep 28. PMID: 32985606
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Sep 10 ;9(1):13045. Epub 2019 Sep 10. PMID: 31506575
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Additional Keywords : Selective Cytotoxicity
[+]
Pubmed Data : Int J Oncol. 2017 Sep ;51(3):939-948. Epub 2017 Jul 31. PMID: 28766690
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 2 ;10(10). Epub 2018 Oct 2. PMID: 30279339
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Hair Loss
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 20 ;10(11). Epub 2018 Nov 20. PMID: 30463345
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Chemoprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Jan 20 ;11(1):1854. Epub 2021 Jan 20. PMID: 33473148
Study Type : In Vitro Study
[+]
Pubmed Data : Food Chem. 2018 Feb 1 ;240:701-706. Epub 2017 Aug 3. PMID: 28946332
Study Type : In Vitro Study
[+]
Pubmed Data : J Agric Food Chem. 2007 Apr 18;55(8):3167-73. Epub 2007 Mar 21. PMID: 17373813
Study Type : In Vitro Study
Additional Links
Substances : Apples, Curcumin
Diseases : Breast Cancer
Pharmacological Actions : NF-kappaB Inhibitor
[+]
Pubmed Data : J Periodontol. 2016 May 13:1-21. Epub 2016 May 13. PMID: 27177287
Study Type : In Vitro Study
[+]
Pubmed Data : J Prosthodont. 2015 Jun ;24(4):296-302. Epub 2014 Sep 14. PMID: 25219289
Study Type : In Vitro Study
Additional Links
Substances : Apple Cider Vinegar
Pharmacological Actions : Antifungal Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2012 ;2012:491759. Epub 2012 Aug 30. PMID: 22970337
Study Type : Review
Additional Links
Substances : Apples
Diseases : Aging
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Nov 18 ;9(11). Epub 2017 Nov 18. PMID: 29156563
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Colon Cancer
[+]
Pubmed Data : Nutrition. 2008 Apr;24(4):366-74. Epub 2008 Feb 11. PMID: 18262392
Study Type : In Vitro Study
Additional Links
Substances : Apples
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(13):5265-71. PMID: 26225664
Study Type : In Vitro Study
Additional Links
Substances : Apple Pectin
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]
Pubmed Data : J Exp Med. 1947 Jun 30;86(1):55-64. PMID: 19871655
Study Type : In Vitro Study
Additional Links
Diseases : Influenza A
[+]
Pubmed Data : Food Res Int. 2017 Oct ;100(Pt 2):132-136. Epub 2017 Aug 19. PMID: 28888433
Study Type : In Vitro Study
Additional Links
Substances : Apple Pectin
Pharmacological Actions : Anti-Bacterial Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(1):e53725. Epub 2013 Jan 23. PMID: 23372666
Study Type : In Vitro Study
[+]
Pubmed Data : J Agric Food Chem. 2008 Nov 12;56(21):9905-10. Epub 2008 Oct 2. PMID: 18828600
Study Type : In Vitro Study
Additional Links
Substances : Apples
Pharmacological Actions : Antioxidants, Antiproliferative
[+]
Pubmed Data : J Agric Food Chem. 2003 Jan 29;51(3):609-14. PMID: 12537430
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : Liver Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
[+]
Pubmed Data : J Agric Food Chem. 2008 Dec 24;56(24):11661-7. PMID: 19053381
Study Type : In Vitro Study
Additional Links
Substances : Apples, Flavonoids
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Phytother Res. 2020 Oct 9. Epub 2020 Oct 9. PMID: 33037751
Study Type : In Vitro Study
[+]
Pubmed Data : Wei Sheng Yan Jiu. 2017 Nov ;46(6):960-964. PMID: 29903207
Study Type : In Vitro Study
[+]
Pubmed Data : Biochem Biophys Res Commun. 2009 Oct 16;388(2):372-6. Epub 2009 Aug 8. PMID: 19666002
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Proanthocyanidins
[+]
Pubmed Data : J Periodontol. 2005 Dec;76(12):2223-9. PMID: 16332233
Study Type : In Vitro Study
Additional Links
Substances : Apples, Hops
[+]
Pubmed Data : Mol Nutr Food Res. 2008 Dec;52(12):1399-407. PMID: 18683822
Study Type : In Vitro Study
Additional Links
Substances : Apples, Catechin , Flavonoids
Pharmacological Actions : Apoptotic, Cell cycle arrest
Additional Keywords : Proanthocyanidins
[+]
Pubmed Data : J Endocrinol. 2011 Mar;208(3):273-83. Epub 2011 Jan 6. PMID: 18855307
Study Type : Review
Additional Links
Substances : Apples
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Int J Mol Med. 2004 Jun;13(6):795-9. PMID: 15138614
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : Stomach Cancer
Pharmacological Actions : Apoptotic
[+]
Pubmed Data : J Med Food. 2010 Dec;13(6):1313-23. Epub 2010 Sep 27. PMID: 20874247
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : Hyperglycemia
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 ;8(9). Epub 2016 Sep 6. PMID: 27608040
Study Type : Review
Additional Links
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Phytomedicine. 2016 Feb 15 ;23(2):200-13. Epub 2016 Jan 5. PMID: 26926182
Study Type : In Vitro Study
[+]
Pubmed Data : Food Sci Biotechnol. 2021 Apr ;30(4):555-564. Epub 2021 Mar 3. PMID: 33936847
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Phytother Res. 2005 Aug;19(8):700-7. PMID: 16177974
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:6268755. Epub 2022 Feb 17. PMID: 35222800
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Thyroid Cancer
[+]
Pubmed Data : Food Funct. 2015 Sep 29. Epub 2015 Sep 29. PMID: 26416794
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Antioxidants, Apoptotic
Additional Keywords : Dose Response
[+]
Pubmed Data : Phytother Res. 2009 Apr;23(4):564-71. PMID: 20002057
Study Type : Review
[+]
Pubmed Data : Phytother Res. 2010 May;24(5):644-8. PMID: 19591126
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anti-Bacterial Agents
[+]
Pubmed Data : Food Chem. 2016 Jun 15 ;201:315-9. Epub 2016 Jan 21. PMID: 26868582
Study Type : In Vitro Study
Additional Links
Substances : Apples, Flavonoids, Onion
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Dec 13 ;11(12). Epub 2019 Dec 13. PMID: 31847069
Study Type : In Vitro Study
Additional Links
Diseases : Hair Loss
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Mol Nutr Food Res. 2009 Oct ;53(10):1263-80. PMID: 19764067
Study Type : In Vitro Study
[+]
Pubmed Data : J Food Biochem. 2021 Sep 18:e13942. Epub 2021 Sep 18. PMID: 34535900
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Hyperglycemia
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(8):e0135840. Epub 2015 Aug 18. PMID: 26284516
Study Type : In Vitro Study
[+]
Pubmed Data : J Food Sci. 2016 Jan 11. Epub 2016 Jan 11. PMID: 26753515
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : DNA damage
[+]
Pubmed Data : J Food Sci. 2016 Jun 6. Epub 2016 Jun 6. PMID: 27272442
Study Type : In Vitro Study
[+]
Pubmed Data : Int J Cancer. 2009 May 1;124(9):2210-9. PMID: 19123483
Study Type : In Vitro Study
Additional Links
Substances : Apples, Pear, Phloretin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]
Pubmed Data : Methods. 2007 Aug;42(4):339-48. PMID: 18158826
Study Type : In Vitro Study
Additional Links
Substances : Apples, Pear, Phloretin
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chem Cent J. 2016 ;10:47. Epub 2016 Aug 2. PMID: 27486478
Study Type : In Vitro Study
Additional Links
Substances : Apples
Pharmacological Actions : Anti-Bacterial Agents, Antioxidants
[+]
Pubmed Data : Sci Total Environ. 2010 Feb 13. Epub 2010 Feb 13. PMID: 11841365
Study Type : In Vitro Study
Additional Links
Substances : Apples
[+]
Pubmed Data : Int Arch Allergy Immunol. 2008;147(3):213-21. Epub 2008 Jul 2. PMID: 18594151
Study Type : In Vitro Study
Additional Links
Substances : Apples, Polyphenols
Diseases : Allergies
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Oct 16 ;9(10). Epub 2020 Oct 16. PMID: 33081239
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chem Pharm Bull (Tokyo). 2023 ;71(4):262-268. PMID: 37005250
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]
Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 2007 Nov-Dec(6):11-6. PMID: 18277535
Study Type : In Vitro Study
Additional Links
Substances : Apple Pectin , Beet, Pectin
Pharmacological Actions : Anti-Bacterial Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Jan 31 ;28(3). Epub 2023 Jan 31. PMID: 36771023
Study Type : In Vitro Study
Additional Links
Substances : Apple, Apple Polyphenols
Diseases : Cancers: All
[+]
Pubmed Data : J Biomater Sci Polym Ed. 2022 Jun ;33(8):995-1011. Epub 2022 Feb 2. PMID: 35044283
Study Type : In Vitro Study
[+]
Pubmed Data : Mol Carcinog. 2009 May;48(5):420-31. PMID: 18767070
Study Type : In Vitro Study
Additional Links
Diseases : Hepatoma
Pharmacological Actions : Apoptotic
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]
Pubmed Data : Nutr Res. 2016 Sep ;36(9):925-36. Epub 2016 Jun 26. PMID: 27632912
Study Type : In Vitro Study
Additional Links
Substances : Apples
Pharmacological Actions : Regenerative
Additional Keywords : Adult Stem Cells
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 ;6:32516. Epub 2016 Sep 2. PMID: 27587238
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antioxidants, Chemopreventive
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2014 Dec 7 ;20(45):17029-36. PMID: 25493015
Study Type : Review
Additional Links
Substances : Apples, Berries: All
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jan 29 ;8(1):1732. Epub 2018 Jan 29. PMID: 29379012
Study Type : In Vitro Study
[+]
Pubmed Data : Food Funct. 2023 Apr 3 ;14(7):3279-3289. Epub 2023 Apr 3. PMID: 36929718
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015;7(6):3959-3998. Epub 2015 May 26. PMID: 26016654
Study Type : Review
Additional Links
Pharmacological Actions : Cardioprotective
Additional Keywords : Microbiota
[+]
Pubmed Data : Bioorg Chem. 2020 Jan 28 ;96:103625. Epub 2020 Jan 28. PMID: 32028059
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Pharmacological Actions : Alpha-glucosidase inhibitor

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Written by Jamie Kiffel-Alcheh
There are plenty of pinkwashed products in support of breast cancer awareness, but why not just cut out the middle man and eat naturally pink anti-breast cancer foods?
More and more women are being prescribed cholesterol-lowering statins and some doctors are even recommending the drugs be added to the water supply or dispensed at the McDonald’s drive-thru windows. However, postmenopausal women using statins may be increasing their risk of diabetes according to a study published by the Archives of Internal Medicine.
Investigators at the University of Alabama at Birmingham, studying the link between disease and nutrition, believe that eating just one cup of blueberries every day prevents cell damage linked to cancer
Once again science has proven that the best health prescription is an apple a day. Researchers say eating one apple every day matches the heart benefits of modern statin drugs without the harmful side effects.
Written by Sayer Ji, Founder
Some of the most powerful medicines on the planet are masquerading around as foods and spices. While they do not lend themselves to being patented, nor will multi-billion dollar human clinical trials ever be funded to prove them efficacious, they have been used since time immemorial to both nourish our bodies, and to prevent and treat disease
Intake of coffee and other foods that contain chlorogenic acids has an inverse association with obesity-related chronic diseases. New evidence also shows that these phenolic compounds may also reduce the risk of breast cancer in post-menopausal women
Written by GMI Reporter
According to the ancient Greeks, the apple represented abundance and fertility. Brides ate an apple on the wedding night to ensure sexual desire and fertility. You might think that’s all a silly superstition. Science might disagree.
Old adages usually survive because they're based on common experience. Everyone has heard the old saying, "an apple a day keeps the doctor away." At least one clinical study has found that this may prove out scientifically, at least for menopausal women.
What makes an apple so good for us? Is it the vitamin C? Vitamin K or B6? Is it the soluble fiber or the insoluble fiber? Is it the potassium or the phytosterols? Or is it the apple?
Green tea may well be the healthiest drink on the planet. Now researchers have discovered one of its active compounds disrupts cancer cell metabolism.
Written by Sayer Ji, Founder
This commonly overlooked superfood protects the body from nuclear fallout, kills a wide range of cancers, and keeps the arteries unclogged -- to name but a few, experimentally confirmed ways in which the apple awakens your inner physician
Old adages usually survive because they're based on common experience. Everyone has heard the old saying, "an apple a day keeps the doctor away." At least one clinical study has found that this may prove out scientifically, at least for menopausal women.
Written by Sayer Ji, Founder
Cholesterol-lowering drugs have been known to hit men 'below the belt' for years, contributing both to erectile dysfunction and low testosterone. Now, new research reveals they actually damage men's testicles and sperm.
Hard as you try, you may not be able to avoid antibiotics completely. In fact, you’re probably even getting a low dose of antibiotics in your apples and cabbage
Once again science has proven that the best health prescription is an apple a day. Researchers say eating one apple every day matches the heart benefits of modern statin drugs without the harmful side effects.
Written by Jamie Kiffel-Alcheh
There are plenty of pinkwashed products in support of breast cancer awareness, but why not just cut out the middle man and eat naturally pink anti-breast cancer foods?
Grapes, a popular fruit easily located on grocery store shelves, have potent health benefits: researchers have studied the benefits of consuming the whole fruit, grape seed extract and resveratrol, a type of phenol found in the skin of grapes. Although high in sugar, grapes and their extracts are a possible therapeutic treatment for a variety of ailments including cardiovascular and obesity-related diseases
Midlife women have been led to believe that hormone replacement therapy is an either or proposition: either you take it or you suffer the symptoms of menopause.
Grapes, a popular fruit easily located on grocery store shelves, have potent health benefits: researchers have studied the benefits of consuming the whole fruit, grape seed extract and resveratrol, a type of phenol found in the skin of grapes. Although high in sugar, grapes and their extracts are a possible therapeutic treatment for a variety of ailments including cardiovascular and obesity-related diseases
These foods can make the difference in who becomes a victim to ovarian cancer, the most lethal gynecological cancer known.
Whether you're an elite athlete or struggling with a flight of stairs, beet juice can make a difference
Intake of coffee and other foods that contain chlorogenic acids has an inverse association with obesity-related chronic diseases. New evidence also shows that these phenolic compounds may also reduce the risk of breast cancer in post-menopausal women
A 2020 study points to apples' ability to mediate significant gut microbial metabolic activity. All it takes: two apples a day
Folklore has always claimed an apple a day keeps the doctor away. Now we also know apples are fast-acting. Eating just one a day for a month can get you significant cardiovascular benefits.

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