Artemisinin

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53 Diseases Researched for Artemisinin
NameACCKFocus
Colorectal Cancer110Locked
Malaria68Locked
Breast Cancer56Locked
Cancers: All66Locked
Cervical Cancer45Locked
Atherosclerosis24Locked
Human Papillomavirus (HPV)34Locked
Lung Cancer44Locked
Pancreatic Cancer34Locked
Gallbladder Cancer23Locked
Inflammation33Locked
Inflammatory Bowel Diseases23Locked
Liver Cancer23Locked
Neuroblastoma23Locked
Brain Cancer12Locked
Cervical Dysplasia12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Diabetes Mellitus: Type 212Locked
Diabetic Complications12Locked
Diabetic Neuropathy12Locked
Diabetic Retinopathy12Locked
Gastric Cancer22Locked
Leishmaniasis22Locked
Oral Cancer22Locked
Ovarian Cancer22Locked
Plasmodium Infections12Locked
Promyelocytic leukemia 22Locked
Prostate Cancer22Locked
Toxoplasma gondii Infection22Locked
Bladder Cancer11Locked
Cancers: Drug Resistant11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Crohn's Disease11Locked
Cytomegalovirus Infections11Locked
Endometrial Cancer11Locked
Epstein-Barr Virus Infections11Locked
Glioma11Locked
HSV-111Locked
Helicobacter Pylori Infection11Locked
Hepatitis B 11Locked
Hepatitis C11Locked
Herpes family viruses11Locked
Hyperuricemia11Locked
Leukemia11Locked
Leukemia: Acute myelogenous leukemia (AML) 11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Lymph Node Metastasis11Locked
Mycobacterium Tuberculosis11Locked
Osteosarcoma11Locked
Protozoan Infections11Locked
Squamous cell carcinoma11Locked
Toxoplasmosis11Locked
Ulcerative Colitis11Locked
38 Pharmacological Actions Researched for Artemisinin
NameACCKFocus
Antiproliferative 1829Locked
Apoptotic2326Locked
Antineoplastic Agents1316Locked
Cell cycle arrest89Locked
Anti-Inflammatory Agents68Locked
Antiviral Agents68Locked
Anti-metastatic56Locked
NF-kappaB Inhibitor56Locked
Chemopreventive45Locked
Anti-atherogenic24Locked
Antimalarials34Locked
Cardioprotective24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor34Locked
Chemotherapeutic33Locked
Anti-Tumor12Locked
Anticarcinogenic Agents22Locked
Antiprotozoal Agents22Locked
Chemoprotective Agents12Locked
Chemosensitizer22Locked
Cyclooxygenase 2 Inhibitors22Locked
Gastrointestinal Agents12Locked
Hepatoprotective12Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor12Locked
Neuroprotective Agents12Locked
Renoprotective12Locked
Tumor Suppressor Protein p53 Upregulation22Locked
Anti-Bacterial Agents11Locked
Antioxidants11Locked
Antiparasitic Agents11Locked
Bcl-2 protein down-regulation11Locked
Cytotoxic11Locked
Enzyme Inhibitors11Locked
Heat Shock Protein Inducer11Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor11Locked
Leishmanicidal11Locked
Prostaglandin PGE2 downregulation11Locked
Radiosensitizer11Locked
Wnt/β-catenin pathway down-regulation11Locked

View the Evidence:
76 Abstracts with Artemisinin Research

[+]

Artesunate has anti-proliferative properties in colorectal cancer and is generally well tolerated.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EBioMedicine. 2015 Jan ;2(1):82-90. Epub 2014 Nov 15. PMID: 26137537
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Artemisinin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative
[+]

A curcumin-artemisinin combination is effective for malaria. May 01, 2006

Pubmed Data : Antimicrob Agents Chemother. 2006 May;50(5):1859-60. PMID: 16641461
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Artemisinin, Curcumin
Diseases : Malaria
Additional Keywords : Natural Substance Synergy
[+]

A whole plant extract of artemisia annua was more effective than pure artemisinin, slowing the evolution of malaria drug resistance and overcoming resistance to artemisinin.Jan 19, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2015 Jan 20 ;112(3):821-6. Epub 2015 Jan 5. PMID: 25561559
Article Published Date : Jan 19, 2015
Study Type : Animal Study
Additional Links
Substances : Artemisinin, Wormwood
Diseases : Malaria, Plasmodium Infections
Pharmacological Actions : Antimalarials, Antiviral Agents
Additional Keywords : Bioavailability, Drug Resistance, Plant Extracts, Superiority of Natural Substances versus Drugs, Whole Plant
[+]

Artemisinin alleviates cerebral ischemia/reperfusion injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:7824436. Epub 2022 Apr 5. PMID: 35422868
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Cerebral Ischemia
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Artemisinin alleviates intestinal inflammation and metabolic disturbance in ulcerative colitis rats induced by DSS.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:6211215. Epub 2022 Apr 19. PMID: 35497913
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation
[+]

Artemisinin ameliorates intestinal inflammation by skewing macrophages to the M2 phenotype and inhibiting epithelial-mesenchymal transitio.Dec 19, 2020

Pubmed Data : Int Immunopharmacol. 2020 Dec 20 ;91:107284. Epub 2020 Dec 20. PMID: 33359851
Article Published Date : Dec 19, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
[+]

Artemisinin and curcumin inhibit Drosophila brain tumor, prolong life span, and restore locomotor activity.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : IUBMB Life. 2014 Jul ;66(7):496-506. Epub 2014 Jun 27. PMID: 24975030
Article Published Date : Jun 30, 2014
Study Type : Insect Study
Additional Links
Substances : Artemisinin, Curcumin
Diseases : Brain Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Natural Substance Synergy
[+]

Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity.Jan 31, 2020

Pubmed Data : Biotech Histochem. 2020 Feb ;95(2):121-128. Epub 2019 Sep 6. PMID: 32064961
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Chemoprotective Agents, Hepatoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.Oct 07, 2019

Pubmed Data : Life Sci. 2019 Oct 8 ;237:116943. Epub 2019 Oct 8. PMID: 31604109
Article Published Date : Oct 07, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]

Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity.Dec 31, 2021

Pubmed Data : Cell Immunol. 2022 03 ;373:104500. Epub 2022 Mar 5. PMID: 35276582
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory
[+]

Artemisinin facilitates motor function recovery by enhancing motoneuronal survival and axonal remyelination.Dec 31, 2020

Pubmed Data : ACS Chem Neurosci. 2021 09 1 ;12(17):3148-3156. Epub 2021 Aug 16. PMID: 34465091
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Brachial Plexus Neuropathies
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]

Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells.Jan 14, 2011

Pubmed Data : Phytomedicine. 2011 Jan 15 ;18(2-3):158-62. Epub 2010 Aug 23. PMID: 20739158
Article Published Date : Jan 14, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Artemisinin may be a potent cancer-chemoprevention agent.Jan 07, 2006

Pubmed Data : Cancer Lett. 2006 Jan 8 ;231(1):43-8. PMID: 16356830
Article Published Date : Jan 07, 2006
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

Artemisinin may be suitable for the treatment of gallbladder cancer.Mar 29, 2016

Pubmed Data : Mol Med Rep. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27035431
Article Published Date : Mar 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma.Aug 31, 2014

Pubmed Data : Oncol Rep. 2014 Sep ;32(3):1094-100. Epub 2014 Jul 11. PMID: 25017372
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Neuroblastoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage.Mar 28, 2022

Pubmed Data : Brain Behav. 2022 Mar 29:e2558. Epub 2022 Mar 29. PMID: 35349764
Article Published Date : Mar 28, 2022
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Cerebral Hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Artesunate, a novel derivative of artemisin, has in vitro and in vivo anticancer activity against pancreatic cancer. It exhibits selective cytotoxicity and has in vivo antitumor activity similar to that of gemcitabine.Apr 01, 2010

Pubmed Data : Cancer Chemother Pharmacol. 2010 Apr;65(5):895-902. Epub 2009 Aug 19. PMID: 19690861
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Drug: Gemcitabine, Selective Cytotoxicity, Superiority of Natural Substances versus Drugs
[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives strongly inhibits human papillomavirus-induced tumor formation. Dec 01, 2005

Pubmed Data : Cancer Res. 2005 Dec 1;65(23):10854-61. PMID: 16322232
Article Published Date : Dec 01, 2005
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Cervical Cancer, Cervical Dysplasia, Human Papillomavirus (HPV)
Pharmacological Actions : Anti-Tumor, Antiviral Agents
[+]

The potential roles of artemisinin and Its derivatives in the treatment of type 2 diabetes mellitus.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:585487. Epub 2020 Nov 26. PMID: 33381036
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications, Diabetic Neuropathy, Diabetic Retinopathy
Pharmacological Actions : Cardioprotective, Neuroprotective Agents, Renoprotective
[+]

This study indicated that artemisinin alleviated atherosclerotic lesions.Dec 30, 2019

Pubmed Data : J Cardiovasc Pharmacol. 2019 Dec 31. Epub 2019 Dec 31. PMID: 31895870
Article Published Date : Dec 30, 2019
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]

3-caffeoylquinic acid augmented cisplatins activity by 2.5 fold in this study. Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ChemMedChem. 2014 Dec ;9(12):2791-7. Epub 2014 Sep 10. PMID: 25209896
Article Published Date : Nov 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Caffeoylquinic Acids
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Natural Substances Versus Drugs
Problem Substances : Cisplatin
[+]

A review of the anti-cancer effects of artemisinin compounds.Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Med Health Sci Res. 2015 Mar-Apr;5(2):93-102. PMID: 25861527
Article Published Date : Feb 28, 2015
Study Type : Review
Additional Links
Substances : Artemisinin
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor
[+]

A review of the anti-cancer natural products isolated from Chinese medicinal herbs.Jul 21, 2011

Pubmed Data : Chin Med. 2011 Jul 22 ;6(1):27. Epub 2011 Jul 22. PMID: 21777476
Article Published Date : Jul 21, 2011
Study Type : Review
Additional Links
Substances : Artemisinin, Berberine, Beta-Elemene, Curcumin, Emodin, Flavonoids, Ginsenosides, Shikonin, Silibinin, Ursolic Acid, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Traditional Chinese Medicine
[+]

A semi-synthetic derivative of artemisinin exhibits anti-cancer activity against human lung cancer cell lines. Sep 16, 2009

Pubmed Data : Cancer Chemother Pharmacol. 2009 Sep 16. PMID: 19756601
Article Published Date : Sep 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Lung Cancer
Pharmacological Actions : Apoptotic
[+]

An extract of A. annua was shown to be a potent inhibitor of TNF-α and a strong inhibitor of PGE2 production in activated neutrophils.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm Res. 2015 ;8:9-14. Epub 2015 Jan 14. PMID: 25609991
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Wormwood
Diseases : Inflammation
Pharmacological Actions : Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation.Jul 25, 2019

Pubmed Data : Biochem Biophys Res Commun. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31358323
Article Published Date : Jul 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Hyperuricemia, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Antitumor activity of artemisinin and its derivatives.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Biotechnol. 2012 ;2012:247597. Epub 2011 Nov 22. PMID: 22174561
Article Published Date : Dec 31, 2011
Study Type : Review
Additional Links
Substances : Artemisinin
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative
[+]

Antiviral effects of artemisinin and its derivatives against SARS-CoV-2 main protease.Jan 21, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Jan 22 ;15(2). Epub 2022 Jan 22. PMID: 35215242
Article Published Date : Jan 21, 2022
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Artemisinin and its derivative inhibits the growth of human osteosarcoma cells.Jan 31, 2014

Pubmed Data : J Med Assoc Thai. 2014 Feb ;97 Suppl 2:S215-21. PMID: 25518197
Article Published Date : Jan 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Osteosarcoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Artemisinin and its derivatives may be good alternatives for treating other non-malarial protozoan infections.Nov 16, 2016

Pubmed Data : Pharmacol Res. 2016 Nov 17 ;117:192-217. Epub 2016 Nov 17. PMID: 27867026
Article Published Date : Nov 16, 2016
Study Type : Review
Additional Links
Substances : Artemisinin
Diseases : Leishmaniasis, Protozoan Infections, Toxoplasma gondii Infection
Pharmacological Actions : Antiprotozoal Agents, Leishmanicidal
[+]

Artemisinin and its derivatives prevent Helicobacter pylori-induced gastric carcinogenesis.May 20, 2019

Pubmed Data : Phytomedicine. 2019 May 21 ;63:152968. Epub 2019 May 21. PMID: 31280140
Article Published Date : May 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Artesunate
Diseases : Gastric Cancer, Helicobacter Pylori Infection
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, NF-kappaB Inhibitor
[+]

Artemisinin blocks prostate cancer growth and cell cycle progression.Jan 22, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biol Chem. 2009 Jan 23 ;284(4):2203-13. Epub 2008 Nov 17. PMID: 19017637
Article Published Date : Jan 22, 2009
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Artemisinin could be an alternative treatment for oral squamous cell carcinoma.Jun 30, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2004 Jul-Aug;24(4):2153-60. PMID: 15330155
Article Published Date : Jun 30, 2004
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antineoplastic Agents, Bcl-2 protein down-regulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Artemisinin could be useful in the treatment of mycobacterium tuberculosis.Jan 31, 2017

Pubmed Data : Nat Chem Biol. 2017 Feb ;13(2):218-225. Epub 2016 Dec 19. PMID: 27992879
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Mycobacterium Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Artemisinin demonstrates anti-cancer activity against oral cancer cells that is more powerful than other commonly used chemotherapeutic drugs.Apr 01, 2007

Pubmed Data : Head Neck. 2007 Apr;29(4):335-40. PMID: 17163469
Article Published Date : Apr 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Wormwood
Diseases : Oral Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Artemisinin derivative ARS4 inhibited growth and intraperitoneal dissemination and metastasis of ovarian cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EBioMedicine. 2016 Dec ;14:44-54. Epub 2016 Nov 23. PMID: 27939426
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Ovarian Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Artemisinin derivatives inhibit non-small cell lung cancer cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2021 ;12(13):4075-4085. Epub 2021 May 13. PMID: 34093811
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Apoptotic
[+]

Artemisinin elevates the ergosterol levels of Candida albicans to synergize with amphotericin B against oral candidiasis.Jun 27, 2021

Pubmed Data : Int J Antimicrob Agents. 2021 Jun 28:106394. Epub 2021 Jun 28. PMID: 34197906
Article Published Date : Jun 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Candidiasis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Artemisinin enhances human promyelocytic leukemia cell differentiation.Dec 15, 2003

Pubmed Data : Eur J Pharmacol. 2003 Dec 15;482(1-3):67-76. PMID: 14660006
Article Published Date : Dec 15, 2003
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Promyelocytic leukemia
Pharmacological Actions : Enzyme Inhibitors
[+]

Artemisinin has antiproliferative effects on human breast cancer cells.Mar 31, 2012

Pubmed Data : Anticancer Drugs. 2012 Apr ;23(4):370-9. PMID: 22185819
Article Published Date : Mar 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative
[+]

Artemisinin induces A549 cell apoptosis.Sep 30, 2013

Pubmed Data : Apoptosis. 2013 Oct ;18(10):1201-13. PMID: 23661289
Article Published Date : Sep 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Artemisinin induces antiproliferative and proapoptotic effects in HPV-39-infected ME-180 cells.Aug 31, 2015

Pubmed Data : J Cell Biochem. 2015 Sep ;116(9):1968-81. PMID: 25755006
Article Published Date : Aug 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Cervical Cancer, Human Papillomavirus (HPV)
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Artemisinin induces apoptosis in human cancer cells.Jun 30, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2004 Jul-Aug;24(4):2277-80. PMID: 15330172
Article Published Date : Jun 30, 2004
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Cancers: All
Pharmacological Actions : Apoptotic
[+]

Artemisinin induces caspase-dependent but Bax/Bak-independent apoptosis in ASTC-a-1 cells.Dec 31, 2010

Pubmed Data : J Xray Sci Technol. 2011 ;19(4):545-55. PMID: 25214386
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Artemisinin inhibits gastric cancer cell proliferation through upregulation of p53.Jan 31, 2014

Pubmed Data : Tumour Biol. 2014 Feb ;35(2):1403-9. PMID: 24078446
Article Published Date : Jan 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Artemisinin inhibits neuroblastoma proliferation.May 31, 2014

Pubmed Data : Pharmazie. 2014 Jun ;69(6):468-72. PMID: 24974584
Article Published Date : May 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Neuroblastoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Artemisinin inhibits proliferation of gallbladder cancer cell lines.Feb 29, 2016

Pubmed Data : Zhonghua Wai Ke Za Zhi. 2016 Mar 1 ;54(3):222-7. PMID: 26932893
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Artemisinin inhibits tumor lymphangiogenesis in lymph node metastasis. Jan 01, 2008

Pubmed Data : Pharmacology. 2008;82(2):148-55. Epub 2008 Jul 30. PMID: 18667841
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Lymph Node Metastasis
Pharmacological Actions : Anti-metastatic
[+]

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.Sep 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2018 Sep 18 ;9(1):3801. Epub 2018 Sep 18. PMID: 30228310
Article Published Date : Sep 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Malaria
Pharmacological Actions : Antimalarials
[+]

Artemisinin may be a potentially useful therapeutic agent for inflammatory-related diseases.Jan 31, 2017

Pubmed Data : Immunopharmacol Immunotoxicol. 2017 Feb ;39(1):28-36. Epub 2016 Dec 21. PMID: 28000518
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Artemisinin modulating effect on human breast cancer cell lines with different sensitivity to cytostatics.Feb 28, 2017

Pubmed Data : Exp Oncol. 2017 Mar ;39(1):25-29. PMID: 28361857
Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Antineoplastic Agents, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin
[+]

Artemisinin represents a new potential therapeutic molecule that selectively targets androgen receptor levels.Jan 09, 2017

Pubmed Data : Anticancer Drugs. 2017 10 ;28(9):1018-1031. PMID: 28708672
Article Published Date : Jan 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Prostate Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Artemisinin rewires the protein interaction network in cancer cells.Nov 30, 2013

Pubmed Data : Mol Biosyst. 2013 Dec ;9(12):3091-100. Epub 2013 Oct 2. PMID: 24085322
Article Published Date : Nov 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic
[+]

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells.Nov 30, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2008 Dec ;29(12):2252-8. Epub 2008 Sep 10. PMID: 18784357
Article Published Date : Nov 30, 2008
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Artemisinin selectively induces apoptosis in pancreatic tumor cell line.Jul 31, 2014

Pubmed Data : Chin J Integr Med. 2014 Aug ;20(8):618-23. Epub 2013 Jun 15. PMID: 23771805
Article Published Date : Jul 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Selective Cytotoxicity
[+]

Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis.Jan 28, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jan 29. Epub 2020 Jan 29. PMID: 32007276
Article Published Date : Jan 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions : Apoptotic, Chemosensitizer
[+]

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Drugs. 2014 Mar ;25(3):270-81. PMID: 24296733
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Endometrial Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, NF-kappaB Inhibitor
[+]

Artemisinin triggers induction of cell-cycle arrest and programmed cell death in Leishmania donovani promastigotes.Sep 01, 2007

Pubmed Data : J Med Microbiol. 2007 Sep;56(Pt 9):1213-8. PMID: 17761485
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Leishmaniasis
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Artemisinin, a compound found within the herb wormwood, inhibits a broad range of viruses. Sep 15, 2008

Pubmed Data : Clin Infect Dis. 2008 Sep 15;47(6):804-11. PMID: 18699744
Article Published Date : Sep 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Wormwood
Diseases : Cytomegalovirus Infections, Epstein-Barr Virus Infections, Hepatitis B , Hepatitis C, Herpes family viruses, HSV-1
Pharmacological Actions : Antiviral Agents
[+]

Artemisinin-Ginkgo biloba extract combination therapy for Plasmodium yoelii.Jan 31, 2021

Pubmed Data : Parasitol Int. 2021 Feb ;80:102226. Epub 2020 Nov 1. PMID: 33137498
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Ginkgo biloba
Diseases : Malaria
Pharmacological Actions : Antiviral Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Artesunate could suppress lung-tumor progression by inhibiting Wnt/β-catenin pathway.Apr 21, 2016

Pubmed Data : Oncotarget. 2016 Apr 22. Epub 2016 Apr 22. PMID: 27119499
Article Published Date : Apr 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Artesunate
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Antiproliferative , Cell cycle arrest, Wnt/β-catenin pathway down-regulation
[+]

Artesunate induces apoptosis of bladder cancer cells by miR-16 regulation of COX-2 expression.Aug 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 Aug 15 ;15(8):14298-312. Epub 2014 Aug 15. PMID: 25196524
Article Published Date : Aug 14, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors
[+]

Candidate anti-COVID-19 medicinal plants from Ethiopia.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6622410. Epub 2021 Jun 4. PMID: 34221083
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Allicin, Almond, Apigenin, Artemisinin, Curcumin, EGCG (Epigallocatechin gallate), Gingerol , Hesperidin, Kaempferol, Nobiletin , Oleanolic acid, Piperine, Resveratrol, Rosmarinic acid, Tangeretin , Ursolic Acid
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Combined hyperbaric oxygen and artemisinin exposure may be an effective anticancer chemotherapeutic strategy.Oct 31, 2010

Pubmed Data : Anticancer Res. 2010 Nov ;30(11):4467-70. PMID: 21115894
Article Published Date : Oct 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Leukemia
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Antiproliferative
[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in human promyelocytic leukemia cells. Jul 01, 2008

Pubmed Data : Cancer Biol Ther. 2008 Jul;7(7):1017-23. Epub 2008 Apr 4. PMID: 18414062
Article Published Date : Jul 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in rat glioma cells. Jun 01, 2007

Pubmed Data : J Pharm Pharmacol. 2007 Jun;59(6):849-56. PMID: 17637177
Article Published Date : Jun 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Glioma
Pharmacological Actions : Apoptotic
[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives inhibits the growth of human ovarian cancer cells. Jul 01, 2007

Pubmed Data : Acta Pharmacol Sin. 2007 Jul;28(7):1045-56. PMID: 17588342
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Dihydroartemisinin, a compound derived from wormwood, has inhibitory activity against pancreatic cancer cell growth. Nov 26, 2009

Pubmed Data : J Cancer Res Clin Oncol. 2009 Nov 26. PMID: 19941148
Article Published Date : Nov 26, 2009
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Wormwood
Diseases : Pancreatic Cancer
[+]

Four new nonacetal derivatives of artemisinin have both increased antitoxoplasma activity and decreased cytotoxicity compared to trimethoprim.Nov 30, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2006 Dec ;50(12):4206-8. Epub 2006 Oct 23. PMID: 17060514
Article Published Date : Nov 30, 2006
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents, Antiprotozoal Agents
Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
[+]

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.Jul 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2012 Aug ;56(8):4207-13. Epub 2012 May 21. PMID: 22615284
Article Published Date : Jul 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Psychedelics:All
Diseases : Malaria
Pharmacological Actions : Antimalarials, Heat Shock Protein Inducer
Additional Keywords : Natural Substance Synergy
[+]

Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro.Feb 28, 2009

Pubmed Data : Acta Trop. 2009 Mar ;109(3):194-8. Epub 2008 Nov 20. PMID: 19063856
Article Published Date : Feb 28, 2009
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Licorice
Diseases : Malaria
Pharmacological Actions : Antiviral Agents
Additional Keywords : Natural Substance Synergy
[+]

Selective radiosensitization of human cervical cancer cells and normal cells by artemisinin.May 31, 2012

Pubmed Data : Int J Gynecol Cancer. 2012 Jun ;22(5):718-24. PMID: 22552829
Article Published Date : May 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest, Radiosensitizer
[+]

Synergic effects of artemisinin and resveratrol in cancer cells.Nov 30, 2014

Pubmed Data : J Cancer Res Clin Oncol. 2014 Dec ;140(12):2065-75. Epub 2014 Jul 22. PMID: 25048878
Article Published Date : Nov 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Resveratrol
Diseases : Cervical Cancer, Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells.Oct 31, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2005 Nov-Dec;25(6B):4325-31. PMID: 16309236
Article Published Date : Oct 31, 2005
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Cancers: All
Pharmacological Actions : Cytotoxic
Additional Keywords : Natural Substance Synergy
[+]

These natural inhibitors have been shown to block HPV infection and inhibition of HPV oncoproteins. May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genomics Inform. 2015 Jun ;13(2):60-7. Epub 2015 Jun 30. PMID: 26175664
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin, Berberine, Curcumin, EGCG (Epigallocatechin gallate), Ferulic acid, Gingerol , Indole-3-Carbinol, Resveratrol, Silymarin, Ursolic Acid
Diseases : Human Papillomavirus (HPV)
Pharmacological Actions : Antiviral Agents, Chemopreventive
Additional Keywords : E6 Oncoprotein, Risk Reduction
[+]

This reviews the favorable results from the use of herbal and plant products in inflammatory bowel disease.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Gastroenterol. 2016 Jul-Sep;29(3):268-81. Epub 2016 Feb 20. PMID: 27366027
Article Published Date : Jun 30, 2016
Study Type : Review
Additional Links
Substances : Aloe Vera, Artemisinin, Curcumin, Frankincense, Green Tea, Lemongrass, Panax Notoginseng, Wormwood
Diseases : Crohn's Disease, Inflammatory Bowel Diseases, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts

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