Artemisinin

Name	AC	CK
Malaria	2	4
Human Papillomavirus (HPV)	2	3
Pancreatic Cancer	2	3
Cervical Cancer	1	2
Cervical Dysplasia	1	2
Gallbladder Cancer	1	2
Inflammation	2	2
Leishmaniasis	2	2
Lung Cancer	2	2
Ovarian Cancer	2	2
Plasmodium Infections	1	2
Promyelocytic leukemia	2	2
Toxoplasma gondii Infection	2	2
Breast Cancer	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Crohn's Disease	1	1
Cytomegalovirus Infections	1	1
Epstein-Barr Virus Infections	1	1
Glioma	1	1
HSV-1	1	1
Hepatitis B	1	1
Hepatitis C	1	1
Herpes family viruses	1	1
Inflammatory Bowel Diseases	1	1
Lymph Node Metastasis	1	1
Mycobacterium tuberculosis	1	1
Oral Cancer	1	1
Protozoan Infections	1	1
Toxoplasmosis	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Apoptotic	10	12
Antiviral Agents	4	6
Cell cycle arrest	4	5
Antiproliferative	3	4
Anti-metastatic	3	3
Anti-Inflammatory Agents	2	2
Anti-Tumor	1	2
Antimalarials	1	2
Antineoplastic Agents	1	2
Antiprotozoal Agents	2	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	2
Anti-Bacterial Agents	1	1
Anticarcinogenic Agents	1	1
Antioxidants	1	1
Antiparasitic Agents	1	1
Chemopreventive	1	1
Cyclooxygenase 2 Inhibitors	1	1
Enzyme Inhibitors	1	1
Leishmanicidal	1	1
NF-kappaB Inhibitor	1	1
Prostaglandin PGE2 downregulation	1	1
Wnt/β-catenin pathway down-regulation	1	1

[+]

Artesunate has anti-proliferative properties in colorectal cancer and is generally well tolerated.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : EBioMedicine. 2015 Jan ;2(1):82-90. Epub 2014 Nov 15. PMID: 26137537

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Artemisinin

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative

[+]

A curcumin-artemisinin combination is effective for malaria. May 01, 2006

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Pubmed Data : Antimicrob Agents Chemother. 2006 May;50(5):1859-60. PMID: 16641461

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Artemisinin, Curcumin

Diseases : Malaria

Additional Keywords : Natural Substance Synergy

[+]

A whole plant extract of artemisia annua was more effective than pure artemisinin, slowing the evolution of malaria drug resistance and overcoming resistance to artemisinin.Jan 19, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Proc Natl Acad Sci U S A. 2015 Jan 20 ;112(3):821-6. Epub 2015 Jan 5. PMID: 25561559

Article Published Date : Jan 19, 2015

Study Type : Animal Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Malaria, Plasmodium Infections

Pharmacological Actions : Antimalarials, Antiviral Agents

Additional Keywords : Bioavailability, Drug Resistance, Plant Extracts, Superiority of Natural Substances versus Drugs, Whole Plant

[+]

Artemisinin ameliorates intestinal inflammation by skewing macrophages to the M2 phenotype and inhibiting epithelial-mesenchymal transitio.Dec 19, 2020

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Pubmed Data : Int Immunopharmacol. 2020 Dec 20 ;91:107284. Epub 2020 Dec 20. PMID: 33359851

Article Published Date : Dec 19, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

[+]

Artemisinin and curcumin inhibit Drosophila brain tumor, prolong life span, and restore locomotor activity.Jun 30, 2014

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Pubmed Data : IUBMB Life. 2014 Jul ;66(7):496-506. Epub 2014 Jun 27. PMID: 24975030

Article Published Date : Jun 30, 2014

Study Type : Insect Study

Additional Links

Substances : Artemisinin, Curcumin

Diseases : Brain Cancer

Pharmacological Actions : Antineoplastic Agents

Additional Keywords : Natural Substance Synergy

[+]

Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity.Jan 31, 2020

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Pubmed Data : Biotech Histochem. 2020 Feb ;95(2):121-128. Epub 2019 Sep 6. PMID: 32064961

Article Published Date : Jan 31, 2020

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Chemoprotective Agents, Hepatoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.Oct 07, 2019

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Pubmed Data : Life Sci. 2019 Oct 8 ;237:116943. Epub 2019 Oct 8. PMID: 31604109

Article Published Date : Oct 07, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Atherosclerosis

Pharmacological Actions : Anti-atherogenic

[+]

Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells.Jan 14, 2011

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Pubmed Data : Phytomedicine. 2011 Jan 15 ;18(2-3):158-62. Epub 2010 Aug 23. PMID: 20739158

Article Published Date : Jan 14, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Artemisinin may be a potent cancer-chemoprevention agent.Jan 07, 2006

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Pubmed Data : Cancer Lett. 2006 Jan 8 ;231(1):43-8. PMID: 16356830

Article Published Date : Jan 07, 2006

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

[+]

Artemisinin may be suitable for the treatment of gallbladder cancer.Mar 29, 2016

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Pubmed Data : Mol Med Rep. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27035431

Article Published Date : Mar 29, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Gallbladder Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma.Aug 31, 2014

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Pubmed Data : Oncol Rep. 2014 Sep ;32(3):1094-100. Epub 2014 Jul 11. PMID: 25017372

Article Published Date : Aug 31, 2014

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Neuroblastoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

[+]

Artesunate, a novel derivative of artemisin, has in vitro and in vivo anticancer activity against pancreatic cancer. It exhibits selective cytotoxicity and has in vivo antitumor activity similar to that of gemcitabine.Apr 01, 2010

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Pubmed Data : Cancer Chemother Pharmacol. 2010 Apr;65(5):895-902. Epub 2009 Aug 19. PMID: 19690861

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Pancreatic Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic

Additional Keywords : Drug: Gemcitabine, Selective Cytotoxicity, Superiority of Natural Substances versus Drugs

[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives strongly inhibits human papillomavirus-induced tumor formation. Dec 01, 2005

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Pubmed Data : Cancer Res. 2005 Dec 1;65(23):10854-61. PMID: 16322232

Article Published Date : Dec 01, 2005

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Cervical Cancer, Cervical Dysplasia, Human Papillomavirus (HPV)

Pharmacological Actions : Anti-Tumor, Antiviral Agents

[+]

The potential roles of artemisinin and Its derivatives in the treatment of type 2 diabetes mellitus.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:585487. Epub 2020 Nov 26. PMID: 33381036

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Diabetes Mellitus: Type 2, Diabetic Complications, Diabetic Neuropathy, Diabetic Retinopathy

Pharmacological Actions : Cardioprotective, Neuroprotective Agents, Renoprotective

[+]

This study indicated that artemisinin alleviated atherosclerotic lesions.Dec 30, 2019

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Pubmed Data : J Cardiovasc Pharmacol. 2019 Dec 31. Epub 2019 Dec 31. PMID: 31895870

Article Published Date : Dec 30, 2019

Study Type : Animal Study

Additional Links

Substances : Artemisinin

Diseases : Atherosclerosis

Pharmacological Actions : Anti-atherogenic

[+]

3-caffeoylquinic acid augmented cisplatins activity by 2.5 fold in this study. Nov 30, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : ChemMedChem. 2014 Dec ;9(12):2791-7. Epub 2014 Sep 10. PMID: 25209896

Article Published Date : Nov 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Caffeoylquinic Acids

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Natural Substances Versus Drugs

Problem Substances : Cisplatin

[+]

A review of the anti-cancer effects of artemisinin compounds.Feb 28, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Med Health Sci Res. 2015 Mar-Apr;5(2):93-102. PMID: 25861527

Article Published Date : Feb 28, 2015

Study Type : Review

Additional Links

Substances : Artemisinin

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor

[+]

A review of the anti-cancer natural products isolated from Chinese medicinal herbs.Jul 21, 2011

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Pubmed Data : Chin Med. 2011 Jul 22 ;6(1):27. Epub 2011 Jul 22. PMID: 21777476

Article Published Date : Jul 21, 2011

Study Type : Review

Additional Links

Substances : Artemisinin, Berberine, Beta-Elemene, Curcumin, Emodin, Flavonoids, Ginsenosides, Shikonin, Silibinin, Ursolic Acid, Wogonin

Diseases : Cancers: All

Pharmacological Actions : Chemopreventive, Chemotherapeutic

Additional Keywords : Traditional Chinese Medicine

[+]

A semi-synthetic derivative of artemisinin exhibits anti-cancer activity against human lung cancer cell lines. Sep 16, 2009

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Pubmed Data : Cancer Chemother Pharmacol. 2009 Sep 16. PMID: 19756601

Article Published Date : Sep 16, 2009

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Lung Cancer

Pharmacological Actions : Apoptotic

[+]

An extract of A. annua was shown to be a potent inhibitor of TNF-α and a strong inhibitor of PGE2 production in activated neutrophils.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm Res. 2015 ;8:9-14. Epub 2015 Jan 14. PMID: 25609991

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Inflammation

Pharmacological Actions : Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Dose Response, Plant Extracts

[+]

Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation.Jul 25, 2019

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Pubmed Data : Biochem Biophys Res Commun. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31358323

Article Published Date : Jul 25, 2019

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Hyperuricemia, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Antitumor activity of artemisinin and its derivatives.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biomed Biotechnol. 2012 ;2012:247597. Epub 2011 Nov 22. PMID: 22174561

Article Published Date : Dec 31, 2011

Study Type : Review

Additional Links

Substances : Artemisinin

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative

[+]

Artemisinin and its derivative inhibits the growth of human osteosarcoma cells.Jan 31, 2014

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Pubmed Data : J Med Assoc Thai. 2014 Feb ;97 Suppl 2:S215-21. PMID: 25518197

Article Published Date : Jan 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Osteosarcoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

[+]

Artemisinin and its derivatives may be good alternatives for treating other non-malarial protozoan infections.Nov 16, 2016

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Pubmed Data : Pharmacol Res. 2016 Nov 17 ;117:192-217. Epub 2016 Nov 17. PMID: 27867026

Article Published Date : Nov 16, 2016

Study Type : Review

Additional Links

Substances : Artemisinin

Diseases : Leishmaniasis, Protozoan Infections, Toxoplasma gondii Infection

Pharmacological Actions : Antiprotozoal Agents, Leishmanicidal

[+]

Artemisinin and its derivatives prevent Helicobacter pylori-induced gastric carcinogenesis.May 20, 2019

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Pubmed Data : Phytomedicine. 2019 May 21 ;63:152968. Epub 2019 May 21. PMID: 31280140

Article Published Date : May 20, 2019

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Artesunate

Diseases : Gastric Cancer, Helicobacter Pylori Infection

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, NF-kappaB Inhibitor

[+]

Artemisinin blocks prostate cancer growth and cell cycle progression.Jan 22, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biol Chem. 2009 Jan 23 ;284(4):2203-13. Epub 2008 Nov 17. PMID: 19017637

Article Published Date : Jan 22, 2009

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

[+]

Artemisinin could be an alternative treatment for oral squamous cell carcinoma.Jun 30, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Res. 2004 Jul-Aug;24(4):2153-60. PMID: 15330155

Article Published Date : Jun 30, 2004

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antineoplastic Agents, Bcl-2 protein down-regulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

[+]

Artemisinin could be useful in the treatment of mycobacterium tuberculosis.Jan 31, 2017

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Pubmed Data : Nat Chem Biol. 2017 Feb ;13(2):218-225. Epub 2016 Dec 19. PMID: 27992879

Article Published Date : Jan 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Mycobacterium tuberculosis

Pharmacological Actions : Anti-Bacterial Agents

[+]

Artemisinin demonstrates anti-cancer activity against oral cancer cells that is more powerful than other commonly used chemotherapeutic drugs.Apr 01, 2007

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Pubmed Data : Head Neck. 2007 Apr;29(4):335-40. PMID: 17163469

Article Published Date : Apr 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Oral Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Artemisinin derivative ARS4 inhibited growth and intraperitoneal dissemination and metastasis of ovarian cancer cells.Nov 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : EBioMedicine. 2016 Dec ;14:44-54. Epub 2016 Nov 23. PMID: 27939426

Article Published Date : Nov 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

Artemisinin enhances human promyelocytic leukemia cell differentiation.Dec 15, 2003

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Pubmed Data : Eur J Pharmacol. 2003 Dec 15;482(1-3):67-76. PMID: 14660006

Article Published Date : Dec 15, 2003

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Promyelocytic leukemia

Pharmacological Actions : Enzyme Inhibitors

[+]

Artemisinin has antiproliferative effects on human breast cancer cells.Mar 31, 2012

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Pubmed Data : Anticancer Drugs. 2012 Apr ;23(4):370-9. PMID: 22185819

Article Published Date : Mar 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

[+]

Artemisinin induces A549 cell apoptosis.Sep 30, 2013

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Pubmed Data : Apoptosis. 2013 Oct ;18(10):1201-13. PMID: 23661289

Article Published Date : Sep 30, 2013

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

Artemisinin induces antiproliferative and proapoptotic effects in HPV-39-infected ME-180 cells.Aug 31, 2015

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Pubmed Data : J Cell Biochem. 2015 Sep ;116(9):1968-81. PMID: 25755006

Article Published Date : Aug 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Cervical Cancer, Human Papillomavirus (HPV)

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

Artemisinin induces apoptosis in human cancer cells.Jun 30, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Res. 2004 Jul-Aug;24(4):2277-80. PMID: 15330172

Article Published Date : Jun 30, 2004

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Cancers: All

Pharmacological Actions : Apoptotic

[+]

Artemisinin induces caspase-dependent but Bax/Bak-independent apoptosis in ASTC-a-1 cells.Dec 31, 2010

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Pubmed Data : J Xray Sci Technol. 2011 ;19(4):545-55. PMID: 25214386

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

Artemisinin inhibits gastric cancer cell proliferation through upregulation of p53.Jan 31, 2014

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Pubmed Data : Tumour Biol. 2014 Feb ;35(2):1403-9. PMID: 24078446

Article Published Date : Jan 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Gastric Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation

[+]

Artemisinin inhibits neuroblastoma proliferation.May 31, 2014

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2014 Jun ;69(6):468-72. PMID: 24974584

Article Published Date : May 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Neuroblastoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

[+]

Artemisinin inhibits proliferation of gallbladder cancer cell lines.Feb 29, 2016

Click here to read the entire abstract

Pubmed Data : Zhonghua Wai Ke Za Zhi. 2016 Mar 1 ;54(3):222-7. PMID: 26932893

Article Published Date : Feb 29, 2016

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Gallbladder Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Artemisinin inhibits tumor lymphangiogenesis in lymph node metastasis. Jan 01, 2008

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Pubmed Data : Pharmacology. 2008;82(2):148-55. Epub 2008 Jul 30. PMID: 18667841

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Lymph Node Metastasis

Pharmacological Actions : Anti-metastatic

[+]

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.Sep 17, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nat Commun. 2018 Sep 18 ;9(1):3801. Epub 2018 Sep 18. PMID: 30228310

Article Published Date : Sep 17, 2018

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Malaria

Pharmacological Actions : Antimalarials

[+]

Artemisinin may be a potentially useful therapeutic agent for inflammatory-related diseases.Jan 31, 2017

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Pubmed Data : Immunopharmacol Immunotoxicol. 2017 Feb ;39(1):28-36. Epub 2016 Dec 21. PMID: 28000518

Article Published Date : Jan 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Dose Response

[+]

Artemisinin modulating effect on human breast cancer cell lines with different sensitivity to cytostatics.Feb 28, 2017

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Pubmed Data : Exp Oncol. 2017 Mar ;39(1):25-29. PMID: 28361857

Article Published Date : Feb 28, 2017

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Antineoplastic Agents, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin

[+]

Artemisinin represents a new potential therapeutic molecule that selectively targets androgen receptor levels.Jan 09, 2017

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Pubmed Data : Anticancer Drugs. 2017 10 ;28(9):1018-1031. PMID: 28708672

Article Published Date : Jan 09, 2017

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Prostate Cancer

Pharmacological Actions : Chemotherapeutic

[+]

Artemisinin rewires the protein interaction network in cancer cells.Nov 30, 2013

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Pubmed Data : Mol Biosyst. 2013 Dec ;9(12):3091-100. Epub 2013 Oct 2. PMID: 24085322

Article Published Date : Nov 30, 2013

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Cancers: All

Pharmacological Actions : Chemotherapeutic

[+]

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells.Nov 30, 2008

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Carcinogenesis. 2008 Dec ;29(12):2252-8. Epub 2008 Sep 10. PMID: 18784357

Article Published Date : Nov 30, 2008

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

[+]

Artemisinin selectively induces apoptosis in pancreatic tumor cell line.Jul 31, 2014

Click here to read the entire abstract

Pubmed Data : Chin J Integr Med. 2014 Aug ;20(8):618-23. Epub 2013 Jun 15. PMID: 23771805

Article Published Date : Jul 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Selective Cytotoxicity

[+]

Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis.Jan 28, 2020

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Pubmed Data : Biochem Biophys Res Commun. 2020 Jan 29. Epub 2020 Jan 29. PMID: 32007276

Article Published Date : Jan 28, 2020

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Leukemia: Acute myelogenous leukemia (AML)

Pharmacological Actions : Apoptotic, Chemosensitizer

[+]

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells.Feb 28, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Drugs. 2014 Mar ;25(3):270-81. PMID: 24296733

Article Published Date : Feb 28, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Endometrial Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest, NF-kappaB Inhibitor

[+]

Artemisinin triggers induction of cell-cycle arrest and programmed cell death in Leishmania donovani promastigotes.Sep 01, 2007

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Pubmed Data : J Med Microbiol. 2007 Sep;56(Pt 9):1213-8. PMID: 17761485

Article Published Date : Sep 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Leishmaniasis

Pharmacological Actions : Apoptotic, Cell cycle arrest

[+]

Artemisinin, a compound found within the herb wormwood, inhibits a broad range of viruses. Sep 15, 2008

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Pubmed Data : Clin Infect Dis. 2008 Sep 15;47(6):804-11. PMID: 18699744

Article Published Date : Sep 15, 2008

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Cytomegalovirus Infections, Epstein-Barr Virus Infections, Hepatitis B , Hepatitis C, Herpes family viruses, HSV-1

Pharmacological Actions : Antiviral Agents

[+]

Artemisinin-Ginkgo biloba extract combination therapy for Plasmodium yoelii.Jan 31, 2021

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Pubmed Data : Parasitol Int. 2021 Feb ;80:102226. Epub 2020 Nov 1. PMID: 33137498

Article Published Date : Jan 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Ginkgo biloba

Diseases : Malaria

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Artesunate could suppress lung-tumor progression by inhibiting Wnt/β-catenin pathway.Apr 21, 2016

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Pubmed Data : Oncotarget. 2016 Apr 22. Epub 2016 Apr 22. PMID: 27119499

Article Published Date : Apr 21, 2016

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Artesunate

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Antiproliferative , Cell cycle arrest, Wnt/β-catenin pathway down-regulation

[+]

Artesunate induces apoptosis of bladder cancer cells by miR-16 regulation of COX-2 expression.Aug 14, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2014 Aug 15 ;15(8):14298-312. Epub 2014 Aug 15. PMID: 25196524

Article Published Date : Aug 14, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Bladder Cancer

Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors

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Combined hyperbaric oxygen and artemisinin exposure may be an effective anticancer chemotherapeutic strategy.Oct 31, 2010

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Pubmed Data : Anticancer Res. 2010 Nov ;30(11):4467-70. PMID: 21115894

Article Published Date : Oct 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Leukemia

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Antiproliferative

[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in human promyelocytic leukemia cells. Jul 01, 2008

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Pubmed Data : Cancer Biol Ther. 2008 Jul;7(7):1017-23. Epub 2008 Apr 4. PMID: 18414062

Article Published Date : Jul 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Promyelocytic leukemia

Pharmacological Actions : Apoptotic

[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in rat glioma cells. Jun 01, 2007

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Pubmed Data : J Pharm Pharmacol. 2007 Jun;59(6):849-56. PMID: 17637177

Article Published Date : Jun 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Glioma

Pharmacological Actions : Apoptotic

[+]

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives inhibits the growth of human ovarian cancer cells. Jul 01, 2007

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Pubmed Data : Acta Pharmacol Sin. 2007 Jul;28(7):1045-56. PMID: 17588342

Article Published Date : Jul 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Ovarian Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest

[+]

Dihydroartemisinin, a compound derived from wormwood, has inhibitory activity against pancreatic cancer cell growth. Nov 26, 2009

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Pubmed Data : J Cancer Res Clin Oncol. 2009 Nov 26. PMID: 19941148

Article Published Date : Nov 26, 2009

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Wormwood

Diseases : Pancreatic Cancer

[+]

Four new nonacetal derivatives of artemisinin have both increased antitoxoplasma activity and decreased cytotoxicity compared to trimethoprim.Nov 30, 2006

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antimicrob Agents Chemother. 2006 Dec ;50(12):4206-8. Epub 2006 Oct 23. PMID: 17060514

Article Published Date : Nov 30, 2006

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Toxoplasma gondii Infection, Toxoplasmosis

Pharmacological Actions : Antiparasitic Agents, Antiprotozoal Agents

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.Jul 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antimicrob Agents Chemother. 2012 Aug ;56(8):4207-13. Epub 2012 May 21. PMID: 22615284

Article Published Date : Jul 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Psychedelics:All

Diseases : Malaria

Pharmacological Actions : Antimalarials, Heat Shock Protein Inducer

Additional Keywords : Natural Substance Synergy

[+]

Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro.Feb 28, 2009

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Pubmed Data : Acta Trop. 2009 Mar ;109(3):194-8. Epub 2008 Nov 20. PMID: 19063856

Article Published Date : Feb 28, 2009

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Licorice

Diseases : Malaria

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substance Synergy

[+]

Selective radiosensitization of human cervical cancer cells and normal cells by artemisinin.May 31, 2012

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Pubmed Data : Int J Gynecol Cancer. 2012 Jun ;22(5):718-24. PMID: 22552829

Article Published Date : May 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Cervical Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Radiosensitizer

[+]

Synergic effects of artemisinin and resveratrol in cancer cells.Nov 30, 2014

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Pubmed Data : J Cancer Res Clin Oncol. 2014 Dec ;140(12):2065-75. Epub 2014 Jul 22. PMID: 25048878

Article Published Date : Nov 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Resveratrol

Diseases : Cervical Cancer, Liver Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Natural Substance Synergy

[+]

Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells.Oct 31, 2005

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Res. 2005 Nov-Dec;25(6B):4325-31. PMID: 16309236

Article Published Date : Oct 31, 2005

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin

Diseases : Cancers: All

Pharmacological Actions : Cytotoxic

Additional Keywords : Natural Substance Synergy

[+]

These natural inhibitors have been shown to block HPV infection and inhibition of HPV oncoproteins. May 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genomics Inform. 2015 Jun ;13(2):60-7. Epub 2015 Jun 30. PMID: 26175664

Article Published Date : May 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Berberine, Curcumin, EGCG (Epigallocatechin gallate), Ferulic acid, Gingerol , Indole-3-Carbinol, Resveratrol, Silymarin, Ursolic Acid

Diseases : Human Papillomavirus (HPV)

Pharmacological Actions : Antiviral Agents, Chemopreventive

Additional Keywords : E6 Oncoprotein, Risk Reduction

[+]

This reviews the favorable results from the use of herbal and plant products in inflammatory bowel disease.Jun 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Gastroenterol. 2016 Jul-Sep;29(3):268-81. Epub 2016 Feb 20. PMID: 27366027

Article Published Date : Jun 30, 2016

Study Type : Review

Additional Links

Substances : Aloe Vera, Artemisinin, Curcumin, Frankincense, Green Tea, Lemongrass, Panax Notoginseng, Wormwood

Diseases : Crohn's Disease, Inflammatory Bowel Diseases, Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

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View the Evidence: 67 Abstracts with Artemisinin Research

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Artesunate has anti-proliferative properties in colorectal cancer and is generally well tolerated.Dec 31, 2014

A curcumin-artemisinin combination is effective for malaria. May 01, 2006

A whole plant extract of artemisia annua was more effective than pure artemisinin, slowing the evolution of malaria drug resistance and overcoming resistance to artemisinin.Jan 19, 2015

Artemisinin ameliorates intestinal inflammation by skewing macrophages to the M2 phenotype and inhibiting epithelial-mesenchymal transitio.Dec 19, 2020

Artemisinin and curcumin inhibit Drosophila brain tumor, prolong life span, and restore locomotor activity.Jun 30, 2014

Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity.Jan 31, 2020

Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.Oct 07, 2019

Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells.Jan 14, 2011

Artemisinin may be a potent cancer-chemoprevention agent.Jan 07, 2006

Artemisinin may be suitable for the treatment of gallbladder cancer.Mar 29, 2016

Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma.Aug 31, 2014

Artesunate, a novel derivative of artemisin, has in vitro and in vivo anticancer activity against pancreatic cancer. It exhibits selective cytotoxicity and has in vivo antitumor activity similar to that of gemcitabine.Apr 01, 2010

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives strongly inhibits human papillomavirus-induced tumor formation. Dec 01, 2005

The potential roles of artemisinin and Its derivatives in the treatment of type 2 diabetes mellitus.Dec 31, 2019

This study indicated that artemisinin alleviated atherosclerotic lesions.Dec 30, 2019

3-caffeoylquinic acid augmented cisplatins activity by 2.5 fold in this study. Nov 30, 2014

A review of the anti-cancer effects of artemisinin compounds.Feb 28, 2015

A review of the anti-cancer natural products isolated from Chinese medicinal herbs.Jul 21, 2011

A semi-synthetic derivative of artemisinin exhibits anti-cancer activity against human lung cancer cell lines. Sep 16, 2009

An extract of A. annua was shown to be a potent inhibitor of TNF-α and a strong inhibitor of PGE2 production in activated neutrophils.Dec 31, 2014

Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation.Jul 25, 2019

Antitumor activity of artemisinin and its derivatives.Dec 31, 2011

Artemisinin and its derivative inhibits the growth of human osteosarcoma cells.Jan 31, 2014

Artemisinin and its derivatives may be good alternatives for treating other non-malarial protozoan infections.Nov 16, 2016

Artemisinin and its derivatives prevent Helicobacter pylori-induced gastric carcinogenesis.May 20, 2019

Artemisinin blocks prostate cancer growth and cell cycle progression.Jan 22, 2009

Artemisinin could be an alternative treatment for oral squamous cell carcinoma.Jun 30, 2004

Artemisinin could be useful in the treatment of mycobacterium tuberculosis.Jan 31, 2017

Artemisinin demonstrates anti-cancer activity against oral cancer cells that is more powerful than other commonly used chemotherapeutic drugs.Apr 01, 2007

Artemisinin derivative ARS4 inhibited growth and intraperitoneal dissemination and metastasis of ovarian cancer cells.Nov 30, 2016

Artemisinin enhances human promyelocytic leukemia cell differentiation.Dec 15, 2003

Artemisinin has antiproliferative effects on human breast cancer cells.Mar 31, 2012

Artemisinin induces A549 cell apoptosis.Sep 30, 2013

Artemisinin induces antiproliferative and proapoptotic effects in HPV-39-infected ME-180 cells.Aug 31, 2015

Artemisinin induces apoptosis in human cancer cells.Jun 30, 2004

Artemisinin induces caspase-dependent but Bax/Bak-independent apoptosis in ASTC-a-1 cells.Dec 31, 2010

Artemisinin inhibits gastric cancer cell proliferation through upregulation of p53.Jan 31, 2014

Artemisinin inhibits neuroblastoma proliferation.May 31, 2014

Artemisinin inhibits proliferation of gallbladder cancer cell lines.Feb 29, 2016

Artemisinin inhibits tumor lymphangiogenesis in lymph node metastasis. Jan 01, 2008

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.Sep 17, 2018

Artemisinin may be a potentially useful therapeutic agent for inflammatory-related diseases.Jan 31, 2017

Artemisinin modulating effect on human breast cancer cell lines with different sensitivity to cytostatics.Feb 28, 2017

Artemisinin represents a new potential therapeutic molecule that selectively targets androgen receptor levels.Jan 09, 2017

Artemisinin rewires the protein interaction network in cancer cells.Nov 30, 2013

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells.Nov 30, 2008

Artemisinin selectively induces apoptosis in pancreatic tumor cell line.Jul 31, 2014

Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis.Jan 28, 2020

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells.Feb 28, 2014

Artemisinin triggers induction of cell-cycle arrest and programmed cell death in Leishmania donovani promastigotes.Sep 01, 2007

Artemisinin, a compound found within the herb wormwood, inhibits a broad range of viruses. Sep 15, 2008

Artemisinin-Ginkgo biloba extract combination therapy for Plasmodium yoelii.Jan 31, 2021

Artesunate could suppress lung-tumor progression by inhibiting Wnt/β-catenin pathway.Apr 21, 2016

Artesunate induces apoptosis of bladder cancer cells by miR-16 regulation of COX-2 expression.Aug 14, 2014

Combined hyperbaric oxygen and artemisinin exposure may be an effective anticancer chemotherapeutic strategy.Oct 31, 2010

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in human promyelocytic leukemia cells. Jul 01, 2008

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in rat glioma cells. Jun 01, 2007

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives inhibits the growth of human ovarian cancer cells. Jul 01, 2007

Dihydroartemisinin, a compound derived from wormwood, has inhibitory activity against pancreatic cancer cell growth. Nov 26, 2009

Four new nonacetal derivatives of artemisinin have both increased antitoxoplasma activity and decreased cytotoxicity compared to trimethoprim.Nov 30, 2006

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.Jul 31, 2012

Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro.Feb 28, 2009

Selective radiosensitization of human cervical cancer cells and normal cells by artemisinin.May 31, 2012

Synergic effects of artemisinin and resveratrol in cancer cells.Nov 30, 2014

Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells.Oct 31, 2005

These natural inhibitors have been shown to block HPV infection and inhibition of HPV oncoproteins. May 31, 2015

This reviews the favorable results from the use of herbal and plant products in inflammatory bowel disease.Jun 30, 2016

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Artemisinin

View the Evidence:
67 Abstracts with Artemisinin Research