Artichoke

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55 Diseases Researched for Artichoke
NameACCKFocus
Hypercholesterolemia432Locked
Dyspepsia430Locked
Oxidative Stress526Locked
Hepatitis C321Locked
Colon: Irritable220Locked
Irritable Bowel Syndrome220Locked
Nonalcoholic fatty liver disease (NAFLD)220Locked
Dyslipidemias212Locked
Endothelial Dysfunction212Locked
Metabolic Syndrome X212Locked
Constipation110Locked
Delayed Gastric Emptying110Locked
Hyperlipidemia110Locked
Hypertension110Locked
Chemically-Induced Liver Damage59Locked
High Fat Diet36Locked
Anti-gliadin Antibodies: Elevated15Locked
Food Allergies: Wheat15Locked
Acetaminophen (Tylenol) Toxicity 24Locked
Cadmium Poisoning 24Locked
Liver Damage: Drug-Induced24Locked
Obesity24Locked
Dysbiosis: Bifidobacteria Deficiency23Locked
Inflammation23Locked
Aging12Locked
Aging Skin22Locked
Alcoholic Liver Disease12Locked
Atherosclerosis12Locked
Breast Cancer22Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Colitis12Locked
DNA damage12Locked
Diabetic Complications12Locked
Gastritis12Locked
Hepatic Steatosis12Locked
Insulin Resistance12Locked
Kidney Damage12Locked
Kidney Damage: Drug-Induced12Locked
Lipid Peroxidation12Locked
Liver Cirrhosis12Locked
Nicotine/Tobacco Toxicity 12Locked
Pesticide Toxicity 12Locked
Pesticide-Induced Toxicity: Organophosphates12Locked
Schistosomiasis12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Breast Cancer: Triple Negative 11Locked
Cardiovascular Diseases11Locked
Diabetes Mellitus: Type 211Locked
Dysbiosis11Locked
Leukemia11Locked
Liver Cancer11Locked
Periodontal Diseases11Locked
Pseudomonas aeruginosa11Locked
Skin Diseases: Photo-Aging11Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)11Locked
40 Pharmacological Actions Researched for Artichoke
NameACCKFocus
Antioxidants1747Locked
Hypolipidemic847Locked
Hepatoprotective1026Locked
Anticholesteremic Agents322Locked
Anti-Inflammatory Agents821Locked
Gastrointestinal Agents220Locked
Hypoglycemic Agents516Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor212Locked
Antiviral Agents211Locked
Antihypertensive Agents110Locked
Laxative110Locked
Renoprotective36Locked
Anti-Allergic Agents15Locked
Interleukin-6 Downregulation35Locked
Interleukin-1 beta downregulation24Locked
Malondialdehyde Down-regulation24Locked
Superoxide Dismutase Up-regulation24Locked
Cardioprotective12Locked
Catalase Up-Regulation12Locked
Chemoprotective Agents12Locked
Cytoprotective12Locked
Detoxifier12Locked
Genoprotective12Locked
Immunomodulatory12Locked
Immunosuppressive Agents12Locked
Interleukin-10 downregulation12Locked
Alpha-glucosidase inhibitor 11Locked
Anti-metastatic11Locked
Antimicrobial11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Chemopreventive11Locked
Chemosensitizer11Locked
Chemotherapeutic11Locked
Enzyme Inhibitors11Locked
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)11Locked
Interleukin-8 downregulation11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
NF-kappaB Inhibitor11Locked
Vasodilator Agents11Locked

View the Evidence:
72 Abstracts with Artichoke Research

[+]

Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile.Nov 30, 2021

Pubmed Data : Phytother Res. 2021 Dec ;35(12):6607-6623. Epub 2021 Sep 27. PMID: 34569671
Article Published Date : Nov 30, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Artichoke
Diseases : Hyperlipidemia
Pharmacological Actions : Hypolipidemic
Additional Keywords : Plant Extracts
[+]

This meta-analysis provided convincing evidence for antioxidant activity of artichoke in animals.Oct 21, 2018

Pubmed Data : Phytother Res. 2018 Oct 22. Epub 2018 Oct 22. PMID: 30345589
Article Published Date : Oct 21, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Artichoke
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

A combination of artichoke leaf, dandelion root, turmeric root and rosemary essential oil has therapeutic actions in relieving symptoms in functional dyspepsia.Jun 01, 2010

Pubmed Data : Minerva Gastroenterol Dietol. 2010 Jun;56(2):93-9. PMID: 20485248
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Artichoke, Dandelion , Rosemary, Turmeric
Diseases : Dyspepsia
Additional Keywords : Plant Extracts
[+]

A combined nutraceutical showed to improve lipid and glucose metabolism, adipokines pattern, and systemic inflammation in dyslipidemic overweight subjects.Jul 31, 2019

Pubmed Data : Phytother Res. 2019 Aug ;33(8):2094-2101. Epub 2019 Jun 21. PMID: 31225673
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Substances : Artichoke, Bergamot, Chlorogenic Acid, Vitamin C
Diseases : Dyslipidemias
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Hypolipidemic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

A standardized extract of ginger and artichoke significantly promoted gastric emptying in healthy volunteers.Dec 31, 2015

Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Jan ;20(1):146-9. PMID: 26813467
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Artichoke, Ginger
Diseases : Delayed Gastric Emptying
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Plant Extracts
[+]

Artichoke extract has a modest but favourable stastically significant effect on lowering cholesterol levels.Sep 01, 2008

Pubmed Data : Phytomedicine. 2008 Sep;15(9):668-75. PMID: 18424099
Article Published Date : Sep 01, 2008
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Hypercholesterolemia
[+]

Artichoke leaf extract supplementation may improve serum triglyceride level in A allele genotype of FTO-rs9939609 polymorphism in women with MetS.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2018 Jan ;32(1):84-93. Epub 2017 Nov 29. PMID: 29193419
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Metabolic Syndrome X
Additional Keywords : Genomic Variation
[+]

Artichoke leaf extracts have benefits in the management of NASH.Dec 31, 2015

Pubmed Data : Int J Hepatol. 2016 ;2016:4030476. Epub 2016 May 11. PMID: 27293900
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Artichoke leave extract significantly improves fatigue and joint problems in patients with Hepatitis C. Sep 01, 2009

Pubmed Data : Phytomedicine. 2009 Sep;16(9):801-4. Epub 2009 May 8. PMID: 19427774
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Hepatitis C
[+]

Artichoke may have value in improving the condition of hepatitis C patients.Dec 31, 2011

Pubmed Data : Lik Sprava. 2012 Jan-Mar(1-2):102-7. PMID: 23035608
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Artichoke
Additional Keywords : Plant Extracts
[+]

Artichoke positively modulates endothelial function in hypercholesterolemia. Dec 31, 2004

Pubmed Data : Life Sci. 2004 Dec 31;76(7):775-82. PMID: 15581909
Article Published Date : Dec 31, 2004
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Endothelial Dysfunction, Hypercholesterolemia, Hyperlipidemia
[+]

Artichoke reduces symptoms of dyspepsia.Dec 01, 2003

Pubmed Data : Aliment Pharmacol Ther. 2003 Dec;18(11-12):1099-105. PMID: 14653829
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Dyspepsia
[+]

Artichoke reduces symptoms of irritable bowel syndrome - Article 1. Feb 01, 2001

Pubmed Data : Phytother Res. 2001 Feb;15(1):58-61. PMID: 11180525
Article Published Date : Feb 01, 2001
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Colon: Irritable, Irritable Bowel Syndrome
[+]

Artichoke reduces symptoms of irritable bowel syndrome - Article 2. Aug 01, 2004

Pubmed Data : J Altern Complement Med. 2004 Aug;10(4):667-9. PMID: 15353023
Article Published Date : Aug 01, 2004
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Colon: Irritable, Irritable Bowel Syndrome
[+]

Consumption of C. scolymus powder as a rich source of phenolic and antioxidant compounds could potentially improve BMI and SBP in hypertensive patients.Sep 03, 2019

Pubmed Data : Complement Med Res. 2019 Sep 4:1-6. Epub 2019 Sep 4. PMID: 31484191
Article Published Date : Sep 03, 2019
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Dry extracts of artichoke and berberine have beneficial effects in hypercholesterolemic patients.Feb 14, 2019

Pubmed Data : Am J Cardiol. 2019 Feb 15 ;123(4):588-591. Epub 2018 Nov 23. PMID: 30528419
Article Published Date : Feb 14, 2019
Study Type : Human Study
Additional Links
Substances : Artichoke, Berberine
Diseases : Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic
[+]

Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients.Aug 31, 2010

Pubmed Data : J Clin Gastroenterol. 2010 Sep ;44 Suppl 1:S49-53. PMID: 20495470
Article Published Date : Aug 31, 2010
Study Type : Human Study
Additional Links
Substances : Artichoke, Lactobacillus paracasei
Diseases : Constipation
Pharmacological Actions : Laxative
[+]

Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease.Jun 30, 2018

Pubmed Data : Phytother Res. 2018 Jul ;32(7):1382-1387. Epub 2018 Mar 9. PMID: 29520889
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic
[+]

Ginger and artichoke leaf extracts appears efficacious in the treatment of functional dyspepsia and could represent a promising and safe treatment strategy for this frequent disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:915087. Epub 2015 Apr 14. PMID: 25954317
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Artichoke, Ginger
Diseases : Dyspepsia
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

Jerusalem artichoke may provide an ideal sweetener alternative to fructose, etc. Oct 01, 1990

Pubmed Data : Am J Clin Nutr. 1990 Oct;52(4):675-81. PMID: 2206038
Article Published Date : Oct 01, 1990
Study Type : Human Study
Additional Links
Substances : Artichoke
[+]

Metabolic and anti-inflammatory protective properties of human enriched serum following artichoke leaf extract absorption.Jul 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jul 30 ;13(8). Epub 2021 Jul 30. PMID: 34444810
Article Published Date : Jul 29, 2021
Study Type : Human Study
Additional Links
Substances : Artichoke, Polyphenols
Diseases : Chronic Disease
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Wild Egyptian artichoke exhibits strong antiviral activity against hepatitis C virus and may be useful for its treatment.Jun 13, 2016

Pubmed Data : Food Funct. 2016 Jun 14. Epub 2016 Jun 14. PMID: 27296047
Article Published Date : Jun 13, 2016
Study Type : Human Study
Additional Links
Substances : Artichoke
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
[+]

Polyphenol interactions mitigate the immunogenicity and allergenicity of gliadins.Feb 12, 2017

Pubmed Data : J Agric Food Chem. 2017 Feb 13. Epub 2017 Feb 13. PMID: 28190352
Article Published Date : Feb 12, 2017
Study Type : Human In Vitro
Additional Links
Substances : Apple Polyphenols, Artichoke, Cranberry, Green Tea, Polyphenols
Diseases : Anti-gliadin Antibodies: Elevated, Food Allergies: Wheat
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Plant Extracts
[+]

An ethanol extract from the leaves of C. scolymus has anti-hyperglycemic properties.Jun 18, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jun 19 ;17(1):328. Epub 2017 Jun 19. PMID: 28629341
Article Published Date : Jun 18, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Diabetic Complications, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Artichoke extract ameliorates age-related endothelial dysfunction in rats. Jan 01, 2009

Pubmed Data : Ophthalmic Res. 2009;42(2):112-6. Epub 2009 Jun 26. PMID: 16366729
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Aging, Endothelial Dysfunction
[+]

Artichoke extract ameliorates carbon tetrachloride-induced liver damage and oxidative stress in rats. Sep 01, 2008

Pubmed Data : Exp Toxicol Pathol. 2008 Sep;60(6):475-80. Epub 2008 Jun 25. PMID: 18583118
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Chemically-Induced Liver Damage
[+]

Artichoke extract exerts a protective effect against cadmium-induced testicular damage in rats. Oct 01, 2007

Pubmed Data : Biol Trace Elem Res. 2007 Oct;119(1):51-9. PMID: 17914219
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Cadmium Poisoning
[+]

Artichoke extract exhibited significant preventive protective effect against acute alcohol-induced liver injury.Sep 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Sep 11 ;9(9). Epub 2017 Sep 11. PMID: 28891983
Article Published Date : Sep 10, 2017
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Artichoke leaf extract has liver protective effects and causes downregulation of oxidative stress in acute diazinon-induced liver injury.Aug 29, 2019

Pubmed Data : J Basic Clin Physiol Pharmacol. 2019 Aug 30 ;30(5). Epub 2019 Aug 30. PMID: 31469651
Article Published Date : Aug 29, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Chemically-Induced Liver Damage, Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Organophosphate Pesticides
[+]

Artichoke leaf extract is effective against acute gastritis.Feb 01, 2010

Pubmed Data : Biol Pharm Bull. 2010 Feb;33(2):223-9. PMID: 20118544
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Gastritis
[+]

Artichoke leaf extract may be used as a pharmaceutical phytomedicine in the treatment of liver diseases.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Springerplus. 2016 ;5:216. Epub 2016 Feb 29. PMID: 27026910
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment.Jun 30, 2017

Pubmed Data : Exp Parasitol. 2017 Jul ;178:51-59. Epub 2017 May 25. PMID: 28552793
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Liver Cirrhosis, Schistosomiasis
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Artichoke leaves extract has nephroprotective potential against gentamicin in rats.Aug 31, 2016

Pubmed Data : Pak J Pharm Sci. 2016 Sep ;29(5 Suppl):1775-1782. PMID: 28476701
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Chemotherapy-Induced Toxicity: Gentamicin, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Chemoprotective Agents
Additional Keywords : Plant Extracts
[+]

Artichoke thistle extract not only has cholesterol-reducing capacity but also reduces the blood glucose levels and repairs the impaired kidney functions.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2017 Oct ;13(Suppl 3):S430-S436. Epub 2017 Oct 11. PMID: 29142395
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Renoprotective
[+]

Cynara scolymus leaves extract alleviates nandrolone decanoate-induced alterations in testicular function and sperm quality.Jan 31, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Feb ;27(5):5009-5017. Epub 2019 Dec 16. PMID: 31845274
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Cytoprotective
Additional Keywords : Plant Extracts
[+]

Dried Jerusalem artichoke tubers modified the microbiota ecology in the large intestine of young pigs.Jul 31, 2016

Pubmed Data : Arch Anim Nutr. 2016 Aug ;70(4):278-92. PMID: 27216555
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Dysbiosis: Bifidobacteria Deficiency
Additional Keywords : Microbiota
[+]

Effect of Artichoke on cardiac markers, lipid profile and antioxidants levels in tissue of HFD-induced obesity.Sep 27, 2019

Pubmed Data : Arch Physiol Biochem. 2019 Sep 28:1-11. Epub 2019 Sep 28. PMID: 31564131
Article Published Date : Sep 27, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Antioxidants, Cardioprotective, Hypolipidemic
[+]

Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Assoc Med Bras (1992). 2022 Jan ;68(1):87-93. PMID: 34909970
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Hepatoprotective effect of artichoke leaf extracts in comparison with silymarin on acetaminophen-induced hepatotoxicity.Nov 17, 2019

Pubmed Data : J Immunoassay Immunochem. 2019 Nov 18:1-13. Epub 2019 Nov 18. PMID: 31739724
Article Published Date : Nov 17, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke, Silymarin
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Herbal syrup from chicory and artichoke leaves ameliorate liver damage induced by deltamethrin in weanling male rats.Dec 29, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 30. Epub 2019 Dec 30. PMID: 31889279
Article Published Date : Dec 29, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke, Chicory
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Deltamethrin, Pyrethroid insecticide
[+]

Immunomodulatory effect of Cynara scolymus (artichoke) in rats.Oct 23, 2018

Pubmed Data : Phytother Res. 2018 Oct 24. Epub 2018 Oct 24. PMID: 30353592
Article Published Date : Oct 23, 2018
Study Type : Animal Study
Additional Links
Substances : Artichoke
Pharmacological Actions : Immunomodulatory, Immunosuppressive Agents
[+]

Long-term supplementation with a luteolin enriched artichoke leaf extract can prevent adiposity and related metabolic disorders.Jul 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 27 ;10(8). Epub 2018 Jul 27. PMID: 30060507
Article Published Date : Jul 26, 2018
Study Type : Animal Study
Additional Links
Substances : Artichoke, Luteolin
Diseases : Dyslipidemias, Hepatic Steatosis, Inflammation, Insulin Resistance, Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Milk thistle could be a promising pharmacological option for the treatment of NAFLD.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Can J Gastroenterol Hepatol. 2022 ;2022:2868904. Epub 2022 Feb 11. PMID: 35186807
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artichoke, Milk Thistle
Diseases : Diabetes Mellitus: Type 2, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]

Nanozeolites and artichoke leaf extract has the synergetic effect on increasing the urinary excretion of nicotine.Nov 28, 2012

Pubmed Data : Arzneimittelforschung. 2012 Nov 29. Epub 2012 Nov 29. PMID: 23196970
Article Published Date : Nov 28, 2012
Study Type : Animal Study
Additional Links
Substances : Artichoke, Zeolite
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Detoxifier
Additional Keywords : Natural Substance Synergy
Problem Substances : Nicotine
[+]

The histological findings showed a renoprotective effect of artichoke extract.Dec 18, 2019

Pubmed Data : Arch Physiol Biochem. 2019 Dec 19:1-7. Epub 2019 Dec 19. PMID: 31855072
Article Published Date : Dec 18, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : High Fat Diet, Kidney Damage
Pharmacological Actions : Antioxidants, Renoprotective
[+]

The receptacle and stem extracts of artichoke were found to exert higher protective activity on liver and kidney damage induced by paracetamol.Feb 29, 2020

Pubmed Data : J Ethnopharmacol. 2020 Mar 1 ;249:112458. Epub 2019 Dec 4. PMID: 31809787
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Acetaminophen (Tylenol) Toxicity , Kidney Damage: Drug-Induced, Liver Damage: Drug-Induced
Pharmacological Actions : Hepatoprotective, Renoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

The results suggest that JA had beneficial effects on immunity, blood metabolites, intestinal morphometry and hindgut fermentation of rats.May 31, 2015

Pubmed Data : J Sci Food Agric. 2015 Jun ;95(8):1689-96. Epub 2014 Sep 25. PMID: 25123678
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Artichoke
[+]

The role of artichoke leaf tincture in the suppression of DNA damage and atherosclerosis in rats fed an atherogenic diet.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):138-144. PMID: 29409377
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Atherosclerosis, DNA damage
Pharmacological Actions : Antioxidants, Genoprotective
Additional Keywords : Plant Extracts
[+]

These findings suggest that Cynara leaves exert antiobesity and antioxidant liver effects in HFD-induced obese rats.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:4851279. Epub 2019 May 23. PMID: 31240213
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

These results highlight the potential amelioration of inflammatory bowel disease on mice model colitis through artichoke pectin administration.Dec 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2019 Dec 11 ;10(12):7793-7805. PMID: 31781703
Article Published Date : Dec 10, 2019
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

These results suggest that artichoke has shown promising effects against adverse effects of cadmium toxicity.Apr 30, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 May ;24(13):12372-12383. Epub 2017 Mar 29. PMID: 28357802
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Cadmium Poisoning , Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-10 downregulation, Superoxide Dismutase Up-regulation
Problem Substances : Cadmium
[+]

These results suggest that artichoke leaf extract may ameliorate oxidative stress, inflammation and lipid metabolism disorder.Aug 20, 2021

Pubmed Data : Food Funct. 2021 Aug 21 ;12(16):7239-7249. Epub 2021 Jun 24. PMID: 34165128
Article Published Date : Aug 20, 2021
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Hyperlipidemia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

"Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B."Nov 20, 2012

Pubmed Data : Bioorg Med Chem Lett. 2012 Nov 21. Epub 2012 Nov 21. PMID: 23232059
Article Published Date : Nov 20, 2012
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Aging Skin, Skin Diseases: Photo-Aging
Pharmacological Actions : Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)
[+]

An artichoke extract had potential capacity to selectively stimulate the growth of intestinal bacteria associated with good health.Apr 22, 2015

Pubmed Data : Food Funct. 2015 Apr 23. Epub 2015 Apr 23. PMID: 25904284
Article Published Date : Apr 22, 2015
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Prebiotics
Diseases : Dysbiosis, Dysbiosis: Bifidobacteria Deficiency
[+]

An herbal mixture could afford be an excellent natural candidate to combat oxidative stress and counteract hepatic toxins.Sep 11, 2017

Pubmed Data : Chem Biodivers. 2017 Sep 12. Epub 2017 Sep 12. PMID: 28898531
Article Published Date : Sep 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Fig, Mulberry
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Natural Substance Synergy
[+]

Anti-inflammatory effects of heliangin from Jerusalem artichoke leaves might prevent atherosclerosis.Jan 05, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 01 6 ;12(1). Epub 2022 Jan 6. PMID: 35053238
Article Published Date : Jan 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Artichoke and milk thistle pills and syrups as sources of phenolic compounds with antimicrobial activity.Jul 12, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2016 Jul 13 ;7(7):3083-90. PMID: 27273551
Article Published Date : Jul 12, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Milk Thistle
Diseases : Pseudomonas aeruginosa, Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Antimicrobial, Antioxidants
[+]

Artichoke exhibits apoptotic and antiproliferative activity on leukemia cells. Jul 27, 2009

Pubmed Data : BMC Ear Nose Throat Disord. 2009 Jul 27;9:7. PMID: 17705147
Article Published Date : Jul 27, 2009
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Leukemia
[+]

Artichoke extract directly suppresses inflammation and apoptosis in hepatocytes during the development of non-alcoholic fatty liver disease.Sep 30, 2021

Pubmed Data : J Med Food. 2021 Oct ;24(10):1058-1067. Epub 2021 Sep 29. PMID: 34591699
Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Artichoke extract exhibits antioxidant and apoptotic activity relevant to the treatment of human liver cancer. Jan 01, 2008

Pubmed Data : Nutr Cancer. 2008;60(2):276-83. PMID: 18444161
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
[+]

Artichoke extract improved the expression of genes involved in anti-ageing mechanisms.Oct 22, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Oct 23 ;23(11). Epub 2018 Oct 23. PMID: 30360471
Article Published Date : Oct 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Polyphenols
Diseases : Aging Skin
Pharmacological Actions : Anti-Inflammatory Agents, Vasodilator Agents
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Artichoke leaf extract contains broad antimicrobial activity against bacteria, yeast and mold. Dec 01, 2004

Pubmed Data : J Agric Food Chem. 2004 Dec 1;52(24):7272-8. PMID: 15563206
Article Published Date : Dec 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
[+]

Artichoke leaves extracts displayed high potential as a natural source of compounds with antioxidant and anti-inflammatory properties.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:4951937. Epub 2017 Apr 30. PMID: 28539965
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Artichoke polyphenols could be a promising dietary tool either in cancer chemoprevention or/and in cancer treatment as a nonconventional, adjuvant therapy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:363827. Epub 2015 Jun 9. PMID: 26180585
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Polyphenols
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemopreventive, Chemotherapeutic
Additional Keywords : Epigenetic Modification In Cancer, Plant Extracts, Selective Antiproliferation
[+]

Artichoke polyphenols sensitize human breast cancer cells to chemotherapeutic drugs.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:7965435. Epub 2020 Jan 6. PMID: 31998443
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Polyphenols
Diseases : Breast Cancer
Pharmacological Actions : Chemosensitizer
[+]

Cooking artichokes profoundly increases the bioaccessibility of health-promoting, antioxidant constitutents.Apr 14, 2006

Pubmed Data : Biochem Pharmacol. 2006 Apr 14;71(8):1146-54. Epub 2006 Feb 2. PMID: 18759447
Article Published Date : Apr 14, 2006
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Carotenoids, Flavonoids, Polyphenols
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Raw versus Cooked
[+]

Egyptian artichoke contained compounds that inhibited HCV infection in vitro.Dec 08, 2015

Pubmed Data : J Virol. 2015 Dec 9. Epub 2015 Dec 9. PMID: 26656684
Article Published Date : Dec 08, 2015
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Lactobacillus plantarum-fermented purple Jerusalem artichoke regulates blood glucose and has potential use as a dietary supplement.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2016 Jun ;10(3):282-7. Epub 2016 Mar 2. PMID: 27247724
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Fermented Foods and Beverages, Lactobacillus plantarum
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

The presence of wild plants such as artichoke in the Mediterranean diet may largely contribute to its therapeutic profile. Oct 01, 2008

Pubmed Data : Mol Nutr Food Res. 2008 Oct;52(10):1147-52. PMID: 18646006
Article Published Date : Oct 01, 2008
Study Type : Commentary
Additional Links
Substances : Apigenin, Artichoke, Caffeic Acid, Luteolin
Diseases : Cardiovascular Diseases
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Enzyme Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

These results suggest that cynaropicrin may be useful for preventing periodontal diseases.Sep 13, 2018

Pubmed Data : J Nat Med. 2018 Sep 14. Epub 2018 Sep 14. PMID: 30218207
Article Published Date : Sep 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Artichoke
Diseases : Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor
[+]

This article reviews the wide ranging pharmacological effects of artichoke leaf extracts.Nov 30, 2015

Pubmed Data : Plant Foods Hum Nutr. 2015 Dec ;70(4):441-53. PMID: 26310198
Article Published Date : Nov 30, 2015
Study Type : Review
Additional Links
Substances : Artichoke
Pharmacological Actions : Antioxidants, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Artichoke reduces symptoms of dyspepsia. - Article 2Dec 01, 2002

Pubmed Data : Phytomedicine. 2002 Dec;9(8):694-9. PMID: 12587688
Article Published Date : Dec 01, 2002
Additional Links
Substances : Artichoke
Diseases : Dyspepsia

Copyright: asife / 123RF Stock Photo

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