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8 Diseases Researched for Arugula
NameACCKFocus
Breast Cancer12Locked
Diabetes Mellitus: Type 112Locked
Gastric Ulcer12Locked
Mercury Poisoning12Locked
Skin Diseases12Locked
Thrombosis12Locked
DNA damage11Locked
Ulcers11Locked
12 Pharmacological Actions Researched for Arugula
NameACCKFocus
Anti-Inflammatory Agents24Locked
NF-kappaB Inhibitor24Locked
Anticarcinogenic Agents12Locked
Antioxidants12Locked
Antiproliferative 12Locked
Antithrombotic12Locked
Apoptotic12Locked
Bcl-2 protein down-regulation12Locked
Chemopreventive12Locked
Interleukin-1 beta downregulation12Locked
Platelet Aggregation Inhibitors12Locked
Anti-Ulcer Agents11Locked
Related Topics

Arugula is a Sub of the following Topics

View the Evidence:
29 Abstracts with Arugula Research

[+]

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Dec 26 ;12(1). Epub 2022 Dec 26. PMID: 36670903
Article Published Date : Dec 25, 2022
Study Type : Human In Vitro
Additional Links
Substances : Arugula, Isothiocyanate
Diseases : Melanoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Aqueous extract of Eruca Sativa protects human spermatozoa from mitochondrial failure due to bisphenol A exposure.Oct 24, 2018

Pubmed Data : Reprod Toxicol. 2018 Oct 25 ;82:103-110. Epub 2018 Oct 25. PMID: 30393182
Article Published Date : Oct 24, 2018
Study Type : Insect Study
Additional Links
Substances : Arugula
Diseases : Bisphenol Toxicity, Infertility: Male
Additional Keywords : Plant Extracts
[+]

Arugula seed oil (Eruca sativa) ameliorate alloxan induced diabetes mellitus and oxidative stress in rats. Jan 01, 2000

Pubmed Data : Ann Nutr Metab. 2000;44(3):97-100. PMID: 11053894
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Diabetes Mellitus: Type 1
[+]

Arugula seeds (Eruca sativa) contain a compound with significant skin anti-inflammatory activity. May 01, 2009

Pubmed Data : Biofactors. 2009 May-Jun;35(3):295-305. PMID: 19459144
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Arugula seeds (Eruca sativa) have potential gastric anti-ulcer activity. Apr 28, 2009

Pubmed Data : World J Gastroenterol. 2009 Apr 28;15(16):1958-65. PMID: 19399927
Article Published Date : Apr 28, 2009
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Gastric Ulcer
[+]

Arugula seeds (Eruca sativa) possess antioxidant activity and exert a protective effect on mercuric chloride induced renal toxicity.Jun 01, 2007

Pubmed Data : Food Chem Toxicol. 2007 Jun;45(6):910-20. Epub 2006 Nov 29. PMID: 17207565
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Mercury Poisoning
[+]

Beneficial effects of Eruca sativa defatted seed meal on visceral pain and intestinal damage resulting from colitis.Feb 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Feb 17 ;11(4). Epub 2022 Feb 17. PMID: 35206057
Article Published Date : Feb 16, 2022
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Colitis
Pharmacological Actions : Analgesics, Gastrointestinal Agents, Gastroprotective
[+]

E. sativa might be beneficial in chronic diabetes in ameliorating the progression of diabetic neuropathy.Jul 31, 2018

Pubmed Data : Inflammopharmacology. 2018 Aug ;26(4):993-1003. Epub 2017 Nov 20. PMID: 29159712
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Arugula, Kaempferol
Diseases : Diabetic Neuropathy
Pharmacological Actions : Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Eruca sativa meal against diabetic neuropathic pain: An H2S-mediated effect of glucoerucin.Jan 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 08 19 ;24(16). Epub 2019 Aug 19. PMID: 31430978
Article Published Date : Jan 18, 2019
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Diabetic Neuropathies
Pharmacological Actions : Analgesics
[+]

Eruca sativa Mill. presents antiplatelet and antithrombotic activity.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2014 Dec ;6(12):5839-52. Epub 2014 Dec 12. PMID: 25514563
Article Published Date : Nov 30, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Arugula
Diseases : Thrombosis
Pharmacological Actions : Antithrombotic, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Platelet Aggregation Inhibitors
Additional Keywords : Plant Extracts
[+]

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2021 Apr ;35(4):1983-1990. Epub 2020 Nov 3. PMID: 33141966
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Anti-Obesity Agents
[+]

Eruca sativa seed extract may be considered a promising natural product against breast cancer.Dec 31, 2014

Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(18):8411-8. PMID: 26745094
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Breast Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Chemopreventive, NF-kappaB Inhibitor
[+]

Eruca sativa seed extract modulates oxidative stress and apoptosis and up-regulates the expression of Bcl-2 and Bax genes in acrylamide-induced testicular dysfunction.Sep 30, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Oct ;28(38):53249-53266. Epub 2021 May 23. PMID: 34024031
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Acrylamide-induced toxicity, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Acrylamide
[+]

Eruca Sativa seed oil treatment had a protective role by reversing histological changes in the testis induced by nicotine administration.Jul 31, 2016

Pubmed Data : Tissue Cell. 2016 Aug ;48(4):340-8. Epub 2016 May 26. PMID: 27289444
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Testicular Injury: Nicotine-Induced
[+]

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2S‐releasing properties.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2020 Feb ;177(4):824-835. Epub 2019 Apr 15. PMID: 30825379
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Endothelial Dysfunction
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]

Ethyl-acetate extract of tara mira (Eruca sativa) alleviates the inflammation and rheumatoid arthritis.Aug 31, 2021

Pubmed Data : Pak J Pharm Sci. 2021 Sep ;34(5(Supplementary)):1897-1902. PMID: 34836857
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Protective action of Eruca sativa leaves aqueous extracts against bisphenol A-caused in vivo testicular damages.May 31, 2020

Pubmed Data : J Med Food. 2020 Jun ;23(6):600-610. Epub 2019 Dec 20. PMID: 31859581
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Bisphenol Toxicity, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Bisphenol A
[+]

Protective effects of Eruca sativa on abamectin insecticide toxicity in male albino rats.Mar 31, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Apr ;24(10):9702-9712. Epub 2017 Mar 1. PMID: 28251533
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Pesticides
[+]

Therapeutic effect of rocket seeds (Eruca sativa L.) against hydroxyapatite nanoparticles injection induced cardiac toxicity in rats.Jun 30, 2020

Pubmed Data : Pak J Pharm Sci. 2020 Jul ;33(4(Supplementary)):1839-1845. PMID: 33612468
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
Problem Substances : Nanoparticles
[+]

This finding provides pharmacological base to the traditional use of E. sativa in hypertension. Oct 04, 2018

Pubmed Data : J Ethnopharmacol. 2018 Oct 5 ;224:409-420. Epub 2018 Jun 18. PMID: 29913298
Article Published Date : Oct 04, 2018
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]

A fatty acid-rich fraction of Eruca sativa leaf extract exerts antidiabetic effects.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):810-818. PMID: 28112007
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory effect of the natural H2S-donor erucin in vascular endothelium.Dec 08, 2022

Pubmed Data : Int J Mol Sci. 2022 Dec 9 ;23(24). Epub 2022 Dec 9. PMID: 36555238
Article Published Date : Dec 08, 2022
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Endothelial Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Mar ;33(3):845-855. Epub 2019 Jan 10. PMID: 30632211
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Arugula seeds (Eruca sativa) reduce genotoxicity. Jul 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Jul;46(7):2415-21. Epub 2008 Apr 1. PMID: 18479797
Article Published Date : Jul 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : DNA damage
[+]

Cardiovascular benefits of Eruca sativa defatted seed meal extract.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2022 Jun ;36(6):2616-2627. Epub 2022 Apr 27. PMID: 35478197
Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Plant Extracts
[+]

Erucin inhibits proliferation of MCF7 tumor cells by suppressing microtubule dynamics.Dec 31, 2013

Pubmed Data : PLoS One. 2014 ;9(6):e100599. Epub 2014 Jun 20. PMID: 24950293
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

The H 2 S-donor erucin exhibits protective effects against vascular inflammation in human endothelial and smooth muscle cells.Jun 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Jun 15 ;10(6). Epub 2021 Jun 15. PMID: 34203803
Article Published Date : Jun 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Endothelial Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors
[+]

The present study illustrated strong antagonism of urease activity and thus validated scientifically the traditional use of Eruca sativa in ulcer treatment.Mar 18, 2014

Pubmed Data : J Evid Based Complementary Altern Med. 2014 Mar 19 ;19(3):176-180. Epub 2014 Mar 19. PMID: 24647097
Article Published Date : Mar 18, 2014
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Ulcers
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

These results demonstrate the anti inflammatory and neuroprotective effects of Eruca sativa seed extract.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 May ;17(5):6235-6244. Epub 2018 Mar 7. PMID: 29512782
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts

Copyright: smit / 123RF Stock Photo

Arugula Related Articles

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Written by GMI Reporter
You’ve heard it all your life: “Eat your greens.” But did you know that eating just one cup of leafy greens each day makes your brain an average of 11 years younger than someone who skips them?
Microgreens: More Nutrition Packed in Baby Lettuce
Written by Margie King, Health Coach
You may know microgreens as the delicate, colorful garnish on your overpriced and undersized meal at an upscale restaurant. But science says microgreens aren’t just cuter lettuces – they may be more nutritious.
Arugula Rocks Your Nutrition World
Written by GreenMedInfo Research Group
Arugula has become something of a rock star in the world of salad and like all good rock stars, it has surrounded itself with controversy to create mystique and keep the publicity coming
Can The Slow Food Movement Cure The Fast Food Nation?
Written by Tania Melkonian
Slow food moves us in a way that fast food can not. We immerse ourselves in the process of making a meal, nourishing ourselves and others, and enjoying the fruits of our labor, and that of the Earth. Could this movement be the cure for the Fast Food Nation?

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