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8 Diseases Researched for Arugula
NameACCKFocus
Breast Cancer12Locked
Diabetes Mellitus: Type 112Locked
Gastric Ulcer12Locked
Mercury Poisoning12Locked
Skin Diseases12Locked
Thrombosis12Locked
DNA damage11Locked
Ulcers11Locked
12 Pharmacological Actions Researched for Arugula
NameACCKFocus
Anti-Inflammatory Agents24Locked
NF-kappaB Inhibitor24Locked
Anticarcinogenic Agents12Locked
Antioxidants12Locked
Antiproliferative 12Locked
Antithrombotic12Locked
Apoptotic12Locked
Bcl-2 protein down-regulation12Locked
Chemopreventive12Locked
Interleukin-1 beta downregulation12Locked
Platelet Aggregation Inhibitors12Locked
Anti-Ulcer Agents11Locked
Related Topics

Arugula is a Sub of the following Topics

View the Evidence:
29 Abstracts with Arugula Research

[+]

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Dec 26 ;12(1). Epub 2022 Dec 26. PMID: 36670903
Article Published Date : Dec 25, 2022
Study Type : Human In Vitro
Additional Links
Substances : Arugula, Isothiocyanate
Diseases : Melanoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Aqueous extract of Eruca Sativa protects human spermatozoa from mitochondrial failure due to bisphenol A exposure.Oct 24, 2018

Pubmed Data : Reprod Toxicol. 2018 Oct 25 ;82:103-110. Epub 2018 Oct 25. PMID: 30393182
Article Published Date : Oct 24, 2018
Study Type : Insect Study
Additional Links
Substances : Arugula
Diseases : Bisphenol Toxicity, Infertility: Male
Additional Keywords : Plant Extracts
[+]

Arugula seed oil (Eruca sativa) ameliorate alloxan induced diabetes mellitus and oxidative stress in rats. Jan 01, 2000

Pubmed Data : Ann Nutr Metab. 2000;44(3):97-100. PMID: 11053894
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Diabetes Mellitus: Type 1
[+]

Arugula seeds (Eruca sativa) contain a compound with significant skin anti-inflammatory activity. May 01, 2009

Pubmed Data : Biofactors. 2009 May-Jun;35(3):295-305. PMID: 19459144
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Arugula seeds (Eruca sativa) have potential gastric anti-ulcer activity. Apr 28, 2009

Pubmed Data : World J Gastroenterol. 2009 Apr 28;15(16):1958-65. PMID: 19399927
Article Published Date : Apr 28, 2009
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Gastric Ulcer
[+]

Arugula seeds (Eruca sativa) possess antioxidant activity and exert a protective effect on mercuric chloride induced renal toxicity.Jun 01, 2007

Pubmed Data : Food Chem Toxicol. 2007 Jun;45(6):910-20. Epub 2006 Nov 29. PMID: 17207565
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Mercury Poisoning
[+]

Beneficial effects of Eruca sativa defatted seed meal on visceral pain and intestinal damage resulting from colitis.Feb 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Feb 17 ;11(4). Epub 2022 Feb 17. PMID: 35206057
Article Published Date : Feb 16, 2022
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Colitis
Pharmacological Actions : Analgesics, Gastrointestinal Agents, Gastroprotective
[+]

E. sativa might be beneficial in chronic diabetes in ameliorating the progression of diabetic neuropathy.Jul 31, 2018

Pubmed Data : Inflammopharmacology. 2018 Aug ;26(4):993-1003. Epub 2017 Nov 20. PMID: 29159712
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Arugula, Kaempferol
Diseases : Diabetic Neuropathy
Pharmacological Actions : Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Eruca sativa meal against diabetic neuropathic pain: An H2S-mediated effect of glucoerucin.Jan 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 08 19 ;24(16). Epub 2019 Aug 19. PMID: 31430978
Article Published Date : Jan 18, 2019
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Diabetic Neuropathies
Pharmacological Actions : Analgesics
[+]

Eruca sativa Mill. presents antiplatelet and antithrombotic activity.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2014 Dec ;6(12):5839-52. Epub 2014 Dec 12. PMID: 25514563
Article Published Date : Nov 30, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Arugula
Diseases : Thrombosis
Pharmacological Actions : Antithrombotic, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Platelet Aggregation Inhibitors
Additional Keywords : Plant Extracts
[+]

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2021 Apr ;35(4):1983-1990. Epub 2020 Nov 3. PMID: 33141966
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Anti-Obesity Agents
[+]

Eruca sativa seed extract may be considered a promising natural product against breast cancer.Dec 31, 2014

Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(18):8411-8. PMID: 26745094
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Breast Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Chemopreventive, NF-kappaB Inhibitor
[+]

Eruca sativa seed extract modulates oxidative stress and apoptosis and up-regulates the expression of Bcl-2 and Bax genes in acrylamide-induced testicular dysfunction.Sep 30, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Oct ;28(38):53249-53266. Epub 2021 May 23. PMID: 34024031
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Acrylamide-induced toxicity, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Acrylamide
[+]

Eruca Sativa seed oil treatment had a protective role by reversing histological changes in the testis induced by nicotine administration.Jul 31, 2016

Pubmed Data : Tissue Cell. 2016 Aug ;48(4):340-8. Epub 2016 May 26. PMID: 27289444
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Testicular Injury: Nicotine-Induced
[+]

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2S‐releasing properties.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2020 Feb ;177(4):824-835. Epub 2019 Apr 15. PMID: 30825379
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Endothelial Dysfunction
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]

Ethyl-acetate extract of tara mira (Eruca sativa) alleviates the inflammation and rheumatoid arthritis.Aug 31, 2021

Pubmed Data : Pak J Pharm Sci. 2021 Sep ;34(5(Supplementary)):1897-1902. PMID: 34836857
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Protective action of Eruca sativa leaves aqueous extracts against bisphenol A-caused in vivo testicular damages.May 31, 2020

Pubmed Data : J Med Food. 2020 Jun ;23(6):600-610. Epub 2019 Dec 20. PMID: 31859581
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Bisphenol Toxicity, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Bisphenol A
[+]

Protective effects of Eruca sativa on abamectin insecticide toxicity in male albino rats.Mar 31, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Apr ;24(10):9702-9712. Epub 2017 Mar 1. PMID: 28251533
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Pesticides
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Therapeutic effect of rocket seeds (Eruca sativa L.) against hydroxyapatite nanoparticles injection induced cardiac toxicity in rats.Jun 30, 2020

Pubmed Data : Pak J Pharm Sci. 2020 Jul ;33(4(Supplementary)):1839-1845. PMID: 33612468
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
Problem Substances : Nanoparticles
[+]

This finding provides pharmacological base to the traditional use of E. sativa in hypertension. Oct 04, 2018

Pubmed Data : J Ethnopharmacol. 2018 Oct 5 ;224:409-420. Epub 2018 Jun 18. PMID: 29913298
Article Published Date : Oct 04, 2018
Study Type : Animal Study
Additional Links
Substances : Arugula
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]

A fatty acid-rich fraction of Eruca sativa leaf extract exerts antidiabetic effects.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):810-818. PMID: 28112007
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory effect of the natural H2S-donor erucin in vascular endothelium.Dec 08, 2022

Pubmed Data : Int J Mol Sci. 2022 Dec 9 ;23(24). Epub 2022 Dec 9. PMID: 36555238
Article Published Date : Dec 08, 2022
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Endothelial Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Mar ;33(3):845-855. Epub 2019 Jan 10. PMID: 30632211
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Arugula seeds (Eruca sativa) reduce genotoxicity. Jul 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Jul;46(7):2415-21. Epub 2008 Apr 1. PMID: 18479797
Article Published Date : Jul 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : DNA damage
[+]

Cardiovascular benefits of Eruca sativa defatted seed meal extract.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2022 Jun ;36(6):2616-2627. Epub 2022 Apr 27. PMID: 35478197
Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Plant Extracts
[+]

Erucin inhibits proliferation of MCF7 tumor cells by suppressing microtubule dynamics.Dec 31, 2013

Pubmed Data : PLoS One. 2014 ;9(6):e100599. Epub 2014 Jun 20. PMID: 24950293
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

The H 2 S-donor erucin exhibits protective effects against vascular inflammation in human endothelial and smooth muscle cells.Jun 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Jun 15 ;10(6). Epub 2021 Jun 15. PMID: 34203803
Article Published Date : Jun 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Endothelial Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors
[+]

The present study illustrated strong antagonism of urease activity and thus validated scientifically the traditional use of Eruca sativa in ulcer treatment.Mar 18, 2014

Pubmed Data : J Evid Based Complementary Altern Med. 2014 Mar 19 ;19(3):176-180. Epub 2014 Mar 19. PMID: 24647097
Article Published Date : Mar 18, 2014
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Ulcers
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

These results demonstrate the anti inflammatory and neuroprotective effects of Eruca sativa seed extract.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 May ;17(5):6235-6244. Epub 2018 Mar 7. PMID: 29512782
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arugula
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts

Copyright: smit / 123RF Stock Photo

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Microgreens: More Nutrition Packed in Baby Lettuce
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You may know microgreens as the delicate, colorful garnish on your overpriced and undersized meal at an upscale restaurant. But science says microgreens aren’t just cuter lettuces – they may be more nutritious.
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Arugula Rocks Your Nutrition World
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Arugula has become something of a rock star in the world of salad and like all good rock stars, it has surrounded itself with controversy to create mystique and keep the publicity coming

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