Baicalein

Name	AC	CK
Parkinson's Disease	10	35
Alzheimer's Disease	8	12
Myocardial Ischemia	6	12
Cervical Cancer	8	10
Inflammation	7	10
Oxidative Stress	8	10
Breast Cancer	8	9
Carcinoma: Non-Small-Cell Lung	3	9
Lung Cancer	6	8
Cancers: All	7	7
Cancers: Drug Resistant	4	7
Colorectal Cancer	7	7
Gastric Cancer	6	7
Coronavirus Infection	5	6
Lipid Peroxidation	2	6
Liver Damage	3	6
Liver Injury: Ischemia/reperfusion	3	6
Lung Injury: Acute	3	6
Nonalcoholic fatty liver disease (NAFLD)	3	6
Brain Inflammation	3	5
Breast Cancer: Triple Negative	4	5
Endothelial Dysfunction	1	5
Fibrosis	1	5
Lipopolysaccharide-Induced Toxicity	4	5
Liver Cancer	5	5
Osteoarthritis	3	5
Asthma	2	4
Cerebral Ischemia	2	4
Chemically-Induced Liver Damage	2	4
Hyperuricemia	2	4
Ovarian Cancer	4	4
Pancreatic Cancer	3	4
Sepsis	2	4
Cancer Metastasis	3	3
Candida Albicans	3	3
Chemotherapy-Induced Kidney Damage	2	3
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	3
Chemotherapy-Induced Toxicity: Cisplatin	2	3
Colon Cancer	2	3
Depression	2	3
Glaucoma	2	3
Intracerebral Hemorrhage	2	3
Leukemia	2	3
Melanoma	3	3
Prostate Cancer	3	3
Renal tubulointerstitial fibrosis	1	3
Staphylococcus aureus infection	3	3
Aging	1	2
Aneurysm: Aortic	1	2
Autoimmune Diseases	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Cancer: Pain	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Oxaliplatin	1	2
Colitis	1	2
Diabetes: Cognitive Dysfunction	1	2
Epilepsy	1	2
Escherichia coli Infections	2	2
Gastric Ulcers	1	2
Heart Failure	1	2
Hemorrhage: Cerebral	1	2
Herpes Simplex Virus Type 1	2	2
High Fat Diet	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Ischemia	1	2
Kidney Damage	1	2
Migraines	1	2
Mitochondrial Dysfunction	1	2
Myocardial Infarction	1	2
Myocarditis	1	2
Nephropathy	1	2
Obesity	2	2
Oral Cancer	2	2
Osteoporosis	2	2
Pancreatitis	1	2
Prediabetes	1	2
Pseudomonas aeruginosa	2	2
Radiation Induced Illness	1	2
Respiratory Distress Syndrome	1	2
Sarcopenia	1	2
Squamous cell carcinoma	2	2
Staphylococcus epidermidis	2	2
Streptococcus Infections	1	2
Ulcerative Colitis	1	2
Uveoretinitis	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Animal Diseases: Infectious	1	1
Atherosclerosis	1	1
Bladder Cancer	1	1
Brain Cancer Stem Cells	1	1
Breast Cancer Stem Cells	1	1
Breast Cancer: Lung Metastasis	1	1
Cancer Stem Cells	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Infection	1	1
Candidiasis	1	1
Chemotherapy and Radiation Toxicity	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Chikungunya Virus	1	1
Cholestasis	1	1
Cholesterol: Oxidation	1	1
Colon Cancer Stem Cells	1	1
Coxsackievirus Infections	1	1
DNA damage	1	1
Dengue	1	1
Dental Caries	1	1
Dental Diseases	1	1
Diabetes: Cataract	1	1
Esophageal Cancer	1	1
Food Allergies	1	1
Glioma	1	1
Hepatoma	1	1
Hypertension: Pulmonary	1	1
Klebsiella Infections	1	1
Liver Cancer Stem Cells	1	1
Lung Inflammation	1	1
Lyme Borreliosis	1	1
Lyme Disease	1	1
MRSA	1	1
Mitochondrial Diseases	1	1
Neurological Conditions	1	1
Non-Small-Cell Lung Carcinoma	1	1
Oral Lichen Planus	1	1
Osteosarcoma	1	1
Periodontal Diseases	1	1
Periodontitis	1	1
Polycystic Ovary Syndrome	1	1
Pulmonary Fibrosis	1	1
Scleroderma: Systemic	1	1
Steptococcus Mutans Infections	1	1
Thyroid Cancer	1	1
Ultraviolet Radiation Induced Damage	1	1

Name	AC	CK
Anti-Inflammatory Agents	41	85
Neuroprotective Agents	24	58
Antioxidants	23	54
Apoptotic	41	51
Antiproliferative	35	43
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	26
Anti-metastatic	23	25
Hepatoprotective	12	23
Anti-Apoptotic	14	22
Interleukin-6 Downregulation	10	19
NF-kappaB Inhibitor	10	14
Anti-Fibrotic	5	12
Chemoprotective Agents	7	12
Cardioprotective	6	10
Matrix metalloproteinase-9 (MMP-9) inhibitor	8	10
Antiviral Agents	9	9
Cell cycle arrest	7	9
Interleukin-1 beta downregulation	5	9
Matrix metalloproteinase-2 (MMP-2) inhibitor	7	9
MicroRNA modulator	8	9
Autophagy Up-regulation	5	8
Angiogenesis Inhibitors	4	7
Anti-Bacterial Agents	6	7
Chemosensitizer	4	7
Immunomodulatory	4	7
Anti-atherogenic	1	5
Renoprotective	3	5
Analgesics	2	4
Antineoplastic Agents	2	4
Bcl-2 protein down-regulation	2	4
Chemopreventive	4	4
Chemotherapeutic	4	4
Gastrointestinal Agents	2	4
Interleukin-4 downregulation	2	4
Nitric Oxide Inhibitor	3	4
Osteoprotective	3	4
Angiogenesis Inducing Agents	2	3
Antidepressive Agents	2	3
Antifungal Agents	3	3
Antimicrobial	3	3
Interleukin-10 upregulation	2	3
Nrf2 activation	2	3
Radiosensitizer	3	3
Wnt/β-catenin pathway down-regulation	2	3
Anti-Asthmatic Agents	1	2
Anti-Ulcer Agents	1	2
Anticonvulsants	1	2
Brain-derived neurotrophic factor modulator	1	2
Caspase-3 Activation	1	2
Cyclin D1 Down-Regulation	1	2
Cyclooxygenase 2 Inhibitors	2	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	2
Interleukin-5 downregulation	1	2
Postaglandin PGE2 downregulation	2	2
Prophylactic Agents	1	2
Radioprotective	1	2
Survivin Down-Regulation	1	2
Transforming growth factor beta (TGF-β) inhibitor	2	2
Tumor Suppressor Protein p53 Upregulation	1	2
Uricosuric Agents	1	2
Wnt/β-catenin signaling pathway modulation	2	2
Xanthine oxidase inhibitor	1	2
Anti-Adipogenic	1	1
Anticarcinogenic Agents	1	1
Autophagy Inhibitors	1	1
Cell Differentiation Inducer	1	1
Chondroprotective	1	1
Cytotoxicity	1	1
Enzyme Inhibitors	1	1
Estrogen Receptor Agonist	1	1
Genoprotective	1	1
Hypolipidemic	1	1
Malondialdehyde Down-regulation	1	1
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	1
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	1
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	1
Multidrug Resistance Gene Modulators	1	1
NF-E2-Related Factor-2 (Nrf2) Modulator	1	1
Neurogenesis	1	1
Osteogenic	1	1
Photoprotective	1	1
Quorum Sensing Inhibition	1	1
Regenerative	1	1
STAT3 Activation	1	1

[+]

Baicalein exerts potential neuroprotective effects through multiple signaling pathways in animal models of Parkinson's disease.Dec 31, 2019

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Pubmed Data : Biomed Pharmacother. 2024 Oct ;179:117415. Epub 2024 Sep 11. PMID: 39265236

Article Published Date : Sep 30, 2024

Study Type : Animal Study, In Vitro Study

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Substances : Baicalein

Diseases : Cancers: Drug Resistant, Cervical Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Baicalein enhances the expansion of hematopoietic and progenitor stem cells and alleviates 5-fluorouracil-induced myelosuppression.Feb 02, 2023

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[+]

Baicalein ameliorates ischemic brain damage through suppressing proinflammatory microglia polarization.Oct 31, 2021

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Pubmed Data : Brain Res. 2021 Nov 1 ;1770:147626. Epub 2021 Aug 19. PMID: 34418356

Article Published Date : Oct 31, 2021

Study Type : Animal Study

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Substances : Baicalein

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor

[+]

Baicalein ameliorates myocardial ischemia through reduction of oxidative stress, inflammation and apoptosis.Dec 31, 2021

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Pubmed Data : Acta Pharmacol Sin. 2021 Oct 20. Epub 2021 Oct 20. PMID: 34671110

Article Published Date : Oct 19, 2021

Study Type : Animal Study

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Substances : Baicalein

Diseases : Ulcerative Colitis

Pharmacological Actions : Gastrointestinal Agents

[+]

Baicalein and alpha-tocopherol inhibit toll-like receptor pathways in cisplatin-induced nephrotoxicity.Mar 27, 2022

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Pubmed Data : eNeuro. 2024 Sep 19. Epub 2024 Sep 19. PMID: 39299807

Article Published Date : Sep 18, 2024

Study Type : Animal Study

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Substances : Baicalein

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Baicalein is a promising novel analgesic agent for cancer-induced bone pain.Dec 31, 2014

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[+]

Baicalein possesses anti-inflammatory activities by inhibiting α-synuclein aggregation, inflammasome activation and cathepsin B production.Oct 10, 2016

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Pubmed Data : J Ethnopharmacol. 2016 Oct 11. Epub 2016 Aug 11. PMID: 27742410

Article Published Date : Oct 10, 2016

Study Type : Animal Study

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Substances : Baicalein

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Baicalein pre-treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway.Nov 30, 2021

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Baicalein significantly attenuates kidney injury induced by myocardial ischemia and reperfusion.Jan 31, 2016

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Pubmed Data : Planta Med. 2016 Feb ;82(3):181-9. Epub 2015 Nov 9. PMID: 26550790

Article Published Date : Jan 31, 2016

Study Type : Animal Study

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Substances : Baicalein

Diseases : Kidney Damage, Myocardial Ischemia

Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective

[+]

Baicalein significantly improved the biochemical and histopathological condition of Alzheimer's disease in rats.Dec 31, 2015

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Pubmed Data : Neuropsychiatr Dis Treat. 2016 ;12:3145-3152. Epub 2016 Dec 9. PMID: 28003750

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Baicalein

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Alzheimer's disease, Baicalein, Dose Response, Neuroprotective Agents

[+]

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.Dec 31, 2020

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Pubmed Data : J Pharm Anal. 2024 Aug ;14(8):100968. Epub 2024 Mar 24. PMID: 39258173

Article Published Date : Jul 31, 2024

Study Type : Animal Study

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Substances : Baicalein

Diseases : Diabetes: Cognitive Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow.Feb 28, 2023

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Pubmed Data : Behav Brain Res. 2016 Sep 15 ;311:309-21. Epub 2016 May 24. PMID: 27233830

Article Published Date : Sep 14, 2016

Study Type : Animal Study

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Substances : Baicalein

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

This study is the first to demonstrate efficacy of baicalein both in-vitro and in-vivo in NSCLC. Aug 31, 2016

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Pubmed Data : Biochem Biophys Res Commun. 2024 Apr 23 ;705:149670. Epub 2024 Feb 17. PMID: 38442444

Article Published Date : Apr 22, 2024

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Cholestasis

Pharmacological Actions : Hepatoprotective

[+]

Baicalein ameliorated obesity-induced cardiac dysfunction by regulating the mitochondrial unfolded protein response through NRF2 signaling.Mar 31, 2024

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Pubmed Data : Pharm Biol. 2016 May 4:1-12. Epub 2016 May 4. PMID: 27143122

Article Published Date : May 03, 2016

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Colon Cancer

Pharmacological Actions : Antioxidants, NF-E2-Related Factor-2 (Nrf2) Modulator

[+]

Baicalein combinated with taxol at low concentrations could exert synergistic antitumor effects in ovarian cancer cells.Oct 31, 2016

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Pubmed Data : DNA Cell Biol. 2016 Nov ;35(11):646-656. Epub 2016 Jul 14. PMID: 27414207

Article Published Date : Oct 31, 2016

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic

Additional Keywords : Natural Substance/Drug Synergy

[+]

Baicalein combined with cisplatin induced cytotoxicity and apoptosis of A549 cells.Mar 31, 2017

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Pubmed Data : Oncol Lett. 2017 Apr ;13(4):2799-2804. Epub 2017 Feb 16. PMID: 28454469

Article Published Date : Mar 31, 2017

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Lung Cancer

Pharmacological Actions : Apoptotic, Chemotherapeutic, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.Oct 31, 2016

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Pubmed Data : Oncol Rep. 2016 Nov ;36(5):2771-2776. Epub 2016 Aug 19. PMID: 27667548

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Pubmed Data : Hum Exp Toxicol. 2024 ;43:9603271241249990. PMID: 38664950

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Baicalein facilitates gastric cancer cell apoptosis by triggering endoplasmic reticulum stress.Dec 31, 2022

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 ;62(7):55-60. Epub 2016 Jun 30. PMID: 27453273

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oral Lichen Planus

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, NF-kappaB Inhibitor

[+]

Baicalein induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer.Mar 01, 2024

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Pubmed Data : Am J Chin Med. 2017 Jan 13:1-14. Epub 2017 Jan 13. PMID: 28081631

Article Published Date : Jan 12, 2017

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Ovarian Cancer

Pharmacological Actions : Autophagy Up-regulation

Additional Keywords : Autophagy Up-regulation, Baicalein, ovarian cancer

[+]

Baicalein induces cancer cell apoptosis and cause cell cycle arrest. Jul 31, 2016

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Pubmed Data : Med Chem Res. 2016 Aug ;25(8):1515-1523. Epub 2016 Jun 29. PMID: 28008217

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Pubmed Data : Oncol Rep. 2015 Feb ;33(2):737-43. Epub 2014 Dec 11. PMID: 25502212

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Pubmed Data : Antibiotics (Basel). 2021 Feb 21 ;10(2). Epub 2021 Feb 21. PMID: 33670013

Article Published Date : Feb 20, 2021

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Dental Caries, Steptococcus Mutans Infections

Pharmacological Actions : Antimicrobial, Quorum Sensing Inhibition

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

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Pubmed Data : Mol Med Rep. 2017 Jul ;16(1):957-963. Epub 2017 May 30. PMID: 28560420

Article Published Date : Jun 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Cervical Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic

[+]

Baicalein may contribute to dental pulp repair and regenerative endodontics.Dec 31, 2015

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Pubmed Data : Am J Chin Med. 2016 ;44(7):1457-1472. Epub 2016 Oct 25. PMID: 27776430

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Pubmed Data : Biochem Res Int. 2021 ;2021:2319412. Epub 2021 Aug 18. PMID: 34457363

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Parkinson's Disease

Pharmacological Actions : MicroRNA modulator, Neuroprotective Agents

[+]

Baicalein mediates the anti-tumor activity in osteosarcoma.Feb 28, 2022

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Pubmed Data : Adv Clin Exp Med. 2021 Jun 11. Epub 2021 Jun 11. PMID: 34118143

Article Published Date : Jun 10, 2021

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Cervical Cancer

Pharmacological Actions : MicroRNA modulator, Radiosensitizer

[+]

Baicalein potentiated M1 macrophage polarization in cancer through targeting PI3Kγ/ NF-κB signaling.Dec 31, 2020

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Pubmed Data : Oncotarget. 2016 Oct 20. Epub 2016 Aug 20. PMID: 27776344

Article Published Date : Oct 19, 2016

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Atherosclerosis, Cholesterol: Oxidation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Atherosclerosis, Baicalein, Cholesterol: Oxidation

[+]

Baicalein protects against UVB-induced oxidative stress via scavenging ROS, inhibiting apoptosis, and absorbing UV photons.Oct 31, 2016

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Pubmed Data : Biomol Ther (Seoul). 2016 Nov 1 ;24(6):616-622. PMID: 27257012

Article Published Date : Oct 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Oxidative Stress, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Anti-Apoptotic, Photoprotective

Additional Keywords : Baicalein, oxidative stress, Ultraviolet Radiation Induced Damage

[+]

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Pubmed Data : Virol Sin. 2024 Aug ;39(4):685-693. Epub 2024 Jul 16. PMID: 39025463

Article Published Date : Jul 31, 2024

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : Coxsackievirus Infections

Pharmacological Actions : Antiviral Agents

[+]

Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts.Dec 31, 2021

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Baicalein works synergistically with ciproflaxacin against MRSA. Jul 01, 2011

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Pubmed Data : J Ethnopharmacol. 2011 Jul 1. Epub 2011 Jul 1. PMID: 21782012

Article Published Date : Jul 01, 2011

Study Type : In Vitro Study

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Substances : Baicalein

Diseases : MRSA

Additional Keywords : Drug Synergy

[+]

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Pubmed Data : Int J Pharm. 2023 Mar 25 ;635:122778. Epub 2023 Feb 24. PMID: 36842519

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Pubmed Data : Int J Biol Sci. 2016 ;12(9):1093-103. Epub 2016 Jul 22. PMID: 27570483

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Baicalein, Iodine, Luteolin, Rosmarinic acid, Vitamin C, Vitamin D

Diseases : Lyme Borreliosis, Lyme Disease

Pharmacological Actions : Antimicrobial

Additional Keywords : Natural Substance/Drug Synergy

[+]

Promising role of the Scutellaria baicalensis root hydroxyflavone-baicalein in the prevention and treatment of human diseases.Feb 28, 2023

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Pubmed Data : Int J Mol Sci. 2023 Mar 1 ;24(5). Epub 2023 Mar 1. PMID: 36902160

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Pubmed Data : J Pharm Pharm Sci. 2015 ;18(4):661-82. PMID: 26626254

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Baicalein, Crocetin, Resveratrol

Diseases : Cancers: All, Chemotherapy and Radiation Toxicity

Pharmacological Actions : Chemoprotective Agents

Additional Keywords : Traditional Chinese Medicine

[+]

Synergistic combination of baicalein and rifampicin against Staphylococcus aureus biofilms.Dec 31, 2023

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Pubmed Data : Front Microbiol. 2024 ;15:1458267. Epub 2024 Aug 6. PMID: 39165570

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Pubmed Data : CNS Drugs. 2017 Aug ;31(8):639-652. PMID: 28634902

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Pubmed Data : Aging (Albany NY). 2021 Jul 1 ;13. Epub 2021 Jul 1. PMID: 34198266

Article Published Date : Jun 30, 2021

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Osteoporosis

Pharmacological Actions : Osteoprotective

[+]

These findings demonstrate that inhibition of autophagy enhanced apoptotic cell death induced by baicalein treatment in colon cancer.Dec 15, 2020

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Pubmed Data : Mol Ther Oncolytics. 2020 Dec 16 ;19:1-7. Epub 2020 Aug 29. PMID: 33024814

Article Published Date : Dec 15, 2020

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Colorectal Cancer

Pharmacological Actions : Apoptotic

[+]

These findings provide new insights into the antimetastatic mechanism of baicalein.Nov 30, 2016

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View the Evidence: 202 Abstracts with Baicalein Research

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Baicalein exerts potential neuroprotective effects through multiple signaling pathways in animal models of Parkinson's disease.Dec 31, 2019

Baicalein induces caspase-dependent apoptosis in human lung carcinoma A549 cells.Feb 29, 2016

Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21.Jan 01, 2018

These results provide new insight into the possible molecular mechanisms by which baicalein protects against atherogenesis.Jul 11, 2016

Baicalein enhances cisplatin sensitivity in cervical cancer cells by promoting cuproptosis through the Akt pathway.Sep 30, 2024

Baicalein enhances the expansion of hematopoietic and progenitor stem cells and alleviates 5-fluorouracil-induced myelosuppression.Feb 02, 2023

Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro.Apr 14, 2024

Anti-metastatic effects of baicalein by targeting STAT3 activity in breast cancer cells.Dec 31, 2019

Baicalein alleviated myocardial remodelling and improved cardiac function.Jan 14, 2016

Baicalein alleviates cardiomyocyte death.May 31, 2024

Baicalein alleviates depression-like behavior in rotenone- induced Parkinson's disease model.Jul 31, 2021

Baicalein alleviates hyperuricemia by promoting uric acid excretion and inhibiting xanthine oxidase.Dec 31, 2020

Baicalein alleviates non-alcoholic fatty liver disease in mice by ameliorating intestinal barrier dysfunction.Feb 07, 2023

Baicalein alleviates osteoarthritis by protecting subchondral bone, inhibiting angiogenesis and synovial proliferation.May 02, 2021

Baicalein ameliorates ischemic brain damage through suppressing proinflammatory microglia polarization.Oct 31, 2021

Baicalein ameliorates myocardial ischemia through reduction of oxidative stress, inflammation and apoptosis.Dec 31, 2021

Baicalein ameliorates SEB-induced acute respiratory distress syndrome in a microbiota-dependent manner.Sep 18, 2024

Baicalein ameliorates Streptococcus suis-induced infection.May 28, 2021

Baicalein ameliorates ulcerative colitis by improving intestinal epithelial barrier.Oct 19, 2021

Baicalein and alpha-tocopherol inhibit toll-like receptor pathways in cisplatin-induced nephrotoxicity.Mar 27, 2022

Baicalein attenuates acute liver injury by blocking NLRP3 inflammasome.Nov 29, 2020

Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis.Nov 30, 2023

Baicalein attenuates lung injury induced by myocardial ischemia and reperfusion.Dec 31, 2016

Baicalein attenuates radiation-induced inflammatory process in mouse kidney.May 01, 2011

Baicalein could alleviate the migraine-like headaches induced in this study. Mar 22, 2017

Baicalein could ameliorate liver I/R injury via induction of HO-1-mediated autophagy.Dec 31, 2015

Baicalein could attenuate intestinal ischemia-reperfusion injury induced acute lung injury.Feb 28, 2017

Baicalein could be developed into a novel drug for clinical treatment of ICH and ICH-related brain injuries.Jan 20, 2017

Baicalein could be used as a cytoprotective and anti-ulcerogenic agent in gastric ulcers.Oct 21, 2016

Baicalein could increase caspase-3 and Bax expression and decrease survivin and Bcl-2 to induce apoptosis.Aug 31, 2017

Baicalein could prevent the progression of α-syn accumulation in a Parkinson’s disease mouse model.Sep 30, 2016

Baicalein enhances the effect of acarbose on the improvement of nonalcoholic fatty liver disease associated with prediabetes.Aug 31, 2021

Baicalein executed a kidney-protection action in hyperuricemia and therefore may be used as a therapeutic alternative for hyperuricemic nephropathy.Jun 19, 2017

Baicalein exerted antiepileptic effects by regulation of IGF1R in a pilocarpine-induced model.Nov 30, 2020

Baicalein exerts a protective effect on blood-brain barrier disruption in the rat model of Intracerebral hemorrhage.Aug 11, 2016

Baicalein exerts potent S phase cell cycle arrest and pro-apoptotic effects in HCT-116 cells.Oct 31, 2015

Baicalein has a protective effect of on muscle cells.Dec 31, 2015

Baicalein has the potential to suppress breast cancer metastasis.Dec 31, 2015

Baicalein improves learning and memory dysfunction in D-gal induced aging rats.May 25, 2017

Baicalein induces mitochondrial autophagy to prevent Parkinson's disease.Dec 31, 2020

Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo(a)pyrene-induced pulmonary carcinogenesis in mice.Mar 24, 2022

Baicalein inhibits cerebral ischemia-reperfusion injury.Sep 18, 2024

Baicalein is a promising novel analgesic agent for cancer-induced bone pain.Dec 31, 2014

Baicalein may be a potent calorie restriction mimetics candidate for antiaging interventions.Mar 31, 2022

Baicalein may be a potent reagent for acute megakaryoblastic leukemia (AMKL) therapy.Dec 31, 2015

Baicalein may be an effective immunomodulator that attenuates overwhelming inflammatory responses in severe abdominal sepsis.Mar 29, 2022

Baicalein may be effective in the treatment of Parkinson's disease through anti-neuroinflammation.Aug 31, 2017

Baicalein might be an alternative treatment against refractory chronic inflammation.Nov 25, 2016

Baicalein possesses anti-inflammatory activities by inhibiting α-synuclein aggregation, inflammasome activation and cathepsin B production.Oct 10, 2016

Baicalein pre-treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway.Nov 30, 2021

Baicalein pretreatment might have a potential benefit in prevention and terminating ischemic heart diseases like myocardial infarction.Apr 11, 2016

Baicalein protects against MPP +/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson's disease.Oct 15, 2021

Baicalein reduced carbon tetrachloride induced liver damage.Mar 28, 2021

Baicalein reduces liver injury induced by myocardial ischemia and reperfusion.Dec 31, 2015

Baicalein restores the balance of Th17/Treg cells via aryl hydrocarbon receptor to attenuate colitis.Dec 31, 2019

Baicalein reversed the resistance of human A549 lung adenocarcinoma cells to cisplatin.May 31, 2017

Baicalein significantly attenuates kidney injury induced by myocardial ischemia and reperfusion.Jan 31, 2016

Baicalein significantly improved the biochemical and histopathological condition of Alzheimer's disease in rats.Dec 31, 2015

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.Dec 31, 2020

Baicalein upregulates macrophage TREM2 expression via TrKB-CREB1 pathway to attenuate acute inflammatory injury in acute-on-chronic liver failure.Sep 29, 2024

Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation May 31, 2017

Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.Jul 31, 2024

Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow.Feb 28, 2023

Flavonoids can be utilized and developed as natural treatments for ischemia-induced injuries of the central nervous system.Dec 31, 2020

Functional mechanism of baicalein in alleviating severe acute pancreatitis-acute lung injury.Sep 30, 2024

Ginsenoside Rb1 and baicalin might promote the proliferation and differentiation of endogenous neural stem cells.Oct 12, 2017

Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model.May 09, 2024

Intra-articular injection of baicalein inhibits cartilage catabolism and NLRP3 inflammasome signaling in a posttraumatic osteoarthritis model.Dec 31, 2020

Neuroprotective effect of baicalein against oxaliplatin-induced peripheral neuropathy.May 08, 2022

New insights into baicalein's effect on chlorpyrifos-induced liver injury.Mar 07, 2023

Protective effect of baicalein on high fat-induced hepatocytes oxidative damage.May 19, 2021

Saponins, alkaloids and flavonoids can inhibit the clinical symptoms of EAU in rats to a certain extent and reduce cell apoptosis.May 31, 2016

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View the Evidence:
202 Abstracts with Baicalein Research