Benzyl isothiocyanate

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50 Diseases Researched for Benzyl isothiocyanate
NameACCKFocus
Breast Cancer710Locked
Cancers: All55Locked
Cancers: Canine24Locked
Fatty Liver24Locked
Obesity34Locked
Bladder Cancer33Locked
Liver Cancer33Locked
Oxidative Stress23Locked
Pancreatic Cancer23Locked
Prostate Cancer23Locked
Benzo[a]pyrene-induced Toxicity 12Locked
Breast Cancer: Triple Negative 22Locked
Cachexia: Cancer12Locked
Cancer Metastasis22Locked
Cancers: Drug Resistant22Locked
Colon Cancer22Locked
DNA damage12Locked
Drug-Induced Toxicity: Indomethacin12Locked
Epilepsy12Locked
Gastric Ulcer12Locked
Glioblastoma22Locked
Glioblastoma Multiforme12Locked
High Fat Diet12Locked
Hyperglycemia12Locked
Inflammation12Locked
Leukemia12Locked
Liver Damage12Locked
Lymphoma12Locked
Melanoma22Locked
Pseudomonas aeruginosa22Locked
Acute T cell Leukemias11Locked
Aspergillosis11Locked
Bacterial Infections and Mycoses11Locked
Brain Inflammation 11Locked
Chemotherapy-Induced Toxicity: Cisplatin11Locked
Colorectal Cancer11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Gastric Cancer11Locked
Gram-Negative Bacterial Infections11Locked
Gram-Positive Bacterial Infections11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Listeria Infections11Locked
Lung Cancer11Locked
Malaria11Locked
Malignant Melanoma11Locked
Nonalcoholic fatty liver disease (NAFLD)11Locked
Oral Cancer11Locked
Salmonella Infections11Locked
Squamous cell carcinoma11Locked
Staphylococcus aureus infection11Locked
40 Pharmacological Actions Researched for Benzyl isothiocyanate
NameACCKFocus
Apoptotic1619Locked
Antiproliferative 1518Locked
Chemopreventive1012Locked
Anti-metastatic911Locked
Cell cycle arrest57Locked
Antineoplastic Agents56Locked
Anti-Bacterial Agents55Locked
Anticarcinogenic Agents45Locked
Chemotherapeutic45Locked
Anti-Inflammatory Agents44Locked
Hepatoprotective24Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor44Locked
NF-kappaB Inhibitor34Locked
Nrf2 activation24Locked
Interleukin-1 beta downregulation33Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor33Locked
Wnt/β-catenin signaling pathway modulation23Locked
Anti-Apoptotic12Locked
Anti-Cachexic Agents12Locked
Anti-Ulcer Agents12Locked
Antioxidants12Locked
Cyclooxygenase 2 Inhibitors12Locked
Heme oxygenase-1 up-regulation12Locked
Hypolipidemic12Locked
MicroRNA modulator22Locked
Neuroprotective Agents12Locked
Tumor Suppressor Protein p53 Upregulation12Locked
Anti-Adipogenic11Locked
Antifungal Agents11Locked
Antimalarials11Locked
Antiviral Agents11Locked
Bcl-2 protein down-regulation11Locked
Chemoprotective Agents11Locked
Cytotoxic11Locked
Interleukin-6 Downregulation11Locked
Renoprotective11Locked
Survivin Down-Regulation11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked
interleukin-13 down-regulation11Locked
Related Topics

Benzyl isothiocyanate is a Sub of the following Topic

View the Evidence:
58 Abstracts with Benzyl isothiocyanate Research

[+]

Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene.Jul 31, 2011

Pubmed Data : Food Chem Toxicol. 2011 Aug ;49(8):1674-83. Epub 2011 Mar 3. PMID: 21376772
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Catechin , Ellagic Acid
Diseases : Benzo[a]pyrene-induced Toxicity , DNA damage
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Isothiocyanates
Problem Substances : Benzo(a)pyrene
[+]

Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2024 ;15:1330102. Epub 2024 Apr 23. PMID: 38715687
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Epilepsy
Pharmacological Actions : Neuroprotective Agents
[+]

Benzyl isothiocyanate ameliorates high-fat diet-induced hyperglycemia.Dec 22, 2020

Pubmed Data : J Agric Food Chem. 2020 Dec 23 ;68(51):15228-15238. Epub 2020 Dec 10. PMID: 33301311
Article Published Date : Dec 22, 2020
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : High Fat Diet, Hyperglycemia
Pharmacological Actions : Antioxidants, Nrf2 activation
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate and sulforaphane protect against initiation of pancreatic carcinogenesis in hamsters.Sep 28, 2006

Pubmed Data : Cancer Lett. 2006 Sep 28;241(2):275-80. Epub 2006 Jan 4. PMID: 16386831
Article Published Date : Sep 28, 2006
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive, Cyclooxygenase 2 Inhibitors
Additional Keywords : Isothiocyanates, Stilbenes
[+]

Benzyl isothiocyanate induces apoptosis and inhibits tumor growth in canine mammary carcinoma.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2020 ;7:580530. Epub 2020 Nov 11. PMID: 33263014
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Cancers: Canine
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cells.Oct 31, 2018

Pubmed Data : Environ Toxicol. 2018 Nov ;33(11):1097-1104. Epub 2018 Jul 4. PMID: 29972272
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Glioblastoma Multiforme
Pharmacological Actions : Antiproliferative
[+]

Benzyl isothiocyanate inhibits prostate cancer development.Jan 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 02 22 ;17(2):264. Epub 2016 Feb 22. PMID: 26907265
Article Published Date : Jan 21, 2016
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cell cycle arrest, Chemopreventive
Additional Keywords : Isothiocyanates
[+]

Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer.Jan 09, 2017

Pubmed Data : Sci Rep. 2017 Jan 10 ;7:40070. Epub 2017 Jan 10. PMID: 28071670
Article Published Date : Jan 09, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Isothiocyanates
Diseases : Breast Cancer
Pharmacological Actions : Tumor Suppressor Protein p53 Upregulation
[+]

Benzyl isothiocyanate produced by garden cress prevents accumulation of hepatic lipids.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2020 ;66(5):481-487. PMID: 33132353
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Garden Cress (Lepidium sativum)
Diseases : Fatty Liver, Liver Damage
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]

Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Aug ;20(2):1808-1818. Epub 2019 Jun 18. PMID: 31257529
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Wnt/β-catenin signaling pathway modulation
[+]

Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis in indomethacin-induced gastric injury.Jul 06, 2021

Pubmed Data : Food Funct. 2021 Jul 7 ;12(13):6001-6013. Epub 2021 May 26. PMID: 34037056
Article Published Date : Jul 06, 2021
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Ulcer Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Problem Substances : Indomethacin
[+]

The present study indicates that benzyl isothiocyanate has the ability to inhibit breast cancer-induced osteolytic bone resorption in vivo.Feb 08, 2018

Pubmed Data : Carcinogenesis. 2018 Feb 9 ;39(2):134-145. PMID: 29040431
Article Published Date : Feb 08, 2018
Study Type : Transgenic Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer, Cachexia: Cancer
Pharmacological Actions : Anti-Cachexic Agents, Chemotherapeutic
[+]

These findings indicate that benzyl isothiocyanate and phenethyl isothiocyanate ameliorate high fat diet-induced obesity and fatty liver.Jun 25, 2019

Pubmed Data : J Agric Food Chem. 2019 Jun 26 ;67(25):7136-7146. Epub 2019 Jun 18. PMID: 31240929
Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Fatty Liver, Obesity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Anti-Obesity Agents
[+]

This is the first study that provides information on the activity of benzyl isothiocyanate in canine hematopoietic malignancies.Oct 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Oct 29 ;22(21). Epub 2021 Oct 29. PMID: 34769202
Article Published Date : Oct 28, 2021
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Cancers: Canine, Leukemia, Lymphoma
Pharmacological Actions : Apoptotic
[+]

A combination of benzyl isothiocyanate and sulforaphane have potent inhibitory activity in pancreatic cancer cells.Dec 01, 2002

Pubmed Data : Int J Cardiol. 2002 Dec;86(2-3):317-23. PMID: 19712481
Article Published Date : Dec 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Natural Substance Synergy
[+]

A multidrug resistance-associated protein inhibitor is a potential enhancer of the benzyl isothiocyanate-induced apoptosis induction in human colorectal cancer cells.Apr 20, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Apr 21:e22791. Epub 2021 Apr 21. PMID: 33880814
Article Published Date : Apr 20, 2021
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

A review of the role of phytochemicals in cancer prevention.Oct 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 9 ;20(20). Epub 2019 Oct 9. PMID: 31600949
Article Published Date : Oct 08, 2019
Study Type : Review
Additional Links
Substances : Benzyl isothiocyanate , Capsaicin, Catechin , Cucurbitacin B , Isoflavones, Lycopene, Phenethyl isothiocyanate, Piperlongumine
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents
[+]

Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review.May 10, 2021

Pubmed Data : Pharmacol Res. 2021 May 11:105666. Epub 2021 May 11. PMID: 33989764
Article Published Date : May 10, 2021
Study Type : Review
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Antimalarial activity of aqueous extracts of nasturtium and benzyl isothiocyanate.May 14, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2024 May 15 ;29(10). Epub 2024 May 15. PMID: 38792178
Article Published Date : May 14, 2024
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Nasturtium
Diseases : Malaria
Pharmacological Actions : Antimalarials
Additional Keywords : Plant Extracts
[+]

Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma.May 07, 2021

Pubmed Data : Invest New Drugs. 2021 May 8. Epub 2021 May 8. PMID: 33963962
Article Published Date : May 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Malignant Melanoma
Pharmacological Actions : Chemotherapeutic, Cytotoxic
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Benzyl isothiocyanate alters the gene expression with cell cycle regulation and cell death in human brain glioblastoma GBM 8401 cells.Mar 31, 2016

Pubmed Data : Oncol Rep. 2016 Apr ;35(4):2089-96. Epub 2016 Jan 19. PMID: 26781422
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Gene Expression Regulation, Isothiocyanates
[+]

Benzyl isothiocyanate ameliorates high-fat/cholesterol/cholic acid diet-induced nonalcoholic steatohepatitis.Feb 28, 2020

Pubmed Data : Toxicol Appl Pharmacol. 2020 Feb 29 ;393:114941. Epub 2020 Feb 29. PMID: 32126212
Article Published Date : Feb 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion.Aug 31, 2017

Pubmed Data : Int J Oncol. 2017 Sep ;51(3):832-840. Epub 2017 Jul 27. PMID: 28766686
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancer Metastasis, Melanoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate attenuates inflammasome activation in Pseudomonas aeruginosa LPS-stimulated THP-1 cells.Jan 21, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Jan 22 ;23(3). Epub 2022 Jan 22. PMID: 35163151
Article Published Date : Jan 21, 2022
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Benzyl isothiocyanate attenuates the hydrogen peroxide-induced interleukin-13 expression in T lymphocytic leukemia cells.Apr 17, 2018

Pubmed Data : J Biochem Mol Toxicol. 2018 Apr 18:e22054. Epub 2018 Apr 18. PMID: 29667773
Article Published Date : Apr 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Acute T cell Leukemias
Pharmacological Actions : Chemotherapeutic, interleukin-13 down-regulation
[+]

benzyl isothiocyanate can be considered as a promising candidate in cancer chemoprevention. Jun 30, 2016

Pubmed Data : Vojnosanit Pregl. 2016 Jul ;73(7):636-42. PMID: 29314795
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate, Sulforaphane
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate downregulated the expression of virulence factors in staphylococcus aureus.Oct 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 31 ;20(21). Epub 2019 Oct 31. PMID: 31683671
Article Published Date : Oct 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antiviral Agents
[+]

Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2023 ;14:1119568. Epub 2023 Feb 16. PMID: 36876115
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Aspergillosis
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Antifungal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Benzyl isothiocyanate induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells.Nov 30, 2016

Pubmed Data : Environ Toxicol. 2016 Dec ;31(12):1751-1760. Epub 2015 Sep 7. PMID: 28675694
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Glioblastoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate induces apoptotic cell death in gefitinib-resistant NCI-H460 lung cancer cells.Aug 31, 2018

Pubmed Data : Anticancer Res. 2018 Sep ;38(9):5165-5176. PMID: 30194164
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Cancers: Drug Resistant, Lung Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells.Mar 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Mar 21 ;8(12):20220-20234. PMID: 28423628
Article Published Date : Mar 20, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate inhibits breast cancer cell tumorigenesisDec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015 ;8(10):17601-11. Epub 2015 Oct 15. PMID: 26770350
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Chemopreventive, Wnt/β-catenin signaling pathway modulation
[+]

Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells.Aug 31, 2016

Pubmed Data : Int J Mol Med. 2016 Sep ;38(3):912-8. Epub 2016 Jul 6. PMID: 27430883
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate inhibits TNFα-driven lipolysis.Dec 31, 2023

Pubmed Data : Nutr Res. 2024 Jan ;121:95-107. Epub 2023 Nov 15. PMID: 38056034
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Obesity
[+]

Benzyl isothiocyanate is a potential therapeutic approach for oral squamous cell carcinoma.Apr 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2019 Apr 8 ;52(4):e8409. Epub 2019 Apr 8. PMID: 30970087
Article Published Date : Apr 07, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate promotes apoptosis of oral cancer cells via an acute redox stress-mediated DNA damage response.Oct 31, 2016

Pubmed Data : Food Chem Toxicol. 2016 Nov ;97:336-345. Epub 2016 Sep 28. PMID: 27693243
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Oral Cancer, Oxidative Stress
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Isothiocyanates
[+]

Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells.Oct 05, 2019

Pubmed Data : Environ Toxicol. 2019 Oct 6. Epub 2019 Oct 6. PMID: 31587482
Article Published Date : Oct 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Bladder Cancer
Pharmacological Actions : Chemotherapeutic, MicroRNA modulator
[+]

Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells.May 31, 2019

Pubmed Data : Int J Oncol. 2019 Jun ;54(6):2106-2116. Epub 2019 Mar 26. PMID: 30942430
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic, MicroRNA modulator
[+]

Benzyl isothiocyanate triggers apoptosis in gastric adenocarcinoma cells.Dec 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Dec 6 ;9(12). Epub 2019 Dec 6. PMID: 31817791
Article Published Date : Dec 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic
[+]

Benzyl-isothiocyanate induces apoptosis and inhibits migration and invasion of hepatocellular carcinoma cells in vitro.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2017 ;8(2):240-248. Epub 2017 Jan 15. PMID: 28243328
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Survivin Down-Regulation
[+]

Bioactivity-guided identification of anti-adipogenic isothiocyanates in the Moringa oleifera.May 27, 2020

Pubmed Data : Molecules. 2020 May 28 ;25(11). Epub 2020 May 28. PMID: 32481514
Article Published Date : May 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Isothiocyanates, Moringa oleifera
Diseases : Obesity
Pharmacological Actions : Anti-Adipogenic
Additional Keywords : Anti-Obesity Agents
[+]

Breast cancer chemoprevention by benzyl isothiocyanate may be augmented with a combination regimen involving an inhibitor of KLF4.Feb 28, 2019

Pubmed Data : Cancer Prev Res (Phila). 2019 Mar ;12(3):125-134. Epub 2019 Feb 5. PMID: 30723175
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Cancer Stem Cells
[+]

Chemopreventive and antitumor effects of benzyl isothiocynate on liver cancer.Sep 10, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep 11 ;108:65-75. Epub 2018 Sep 11. PMID: 30216802
Article Published Date : Sep 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Chemopreventive, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Chemopreventive effect of aqueous extract of Moringa oleifera leaves and benzyl isothiocyanate on murine mammary carcinogenesis.Mar 19, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2024 Mar 20 ;29(6). Epub 2024 Mar 20. PMID: 38543016
Article Published Date : Mar 19, 2024
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Moringa oleifera
Diseases : Breast Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Isothiocyanates, Plant Extracts
[+]

Dietary isothiocyanates inhibit cancer progression by modulation of epigenome.Jan 08, 2021

Pubmed Data : Semin Cancer Biol. 2021 Jan 9. Epub 2021 Jan 9. PMID: 33434642
Article Published Date : Jan 08, 2021
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Isothiocyanates, Phenethyl isothiocyanate, Sulforaphane
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Epigenetic Modification In Cancer
[+]

Inhibition of Escherichia coli O157:H7 and Salmonella enterica virulence factors by benzyl isothiocyanate.Mar 31, 2020

Pubmed Data : Food Microbiol. 2020 Apr ;86:103303. Epub 2019 Aug 16. PMID: 31703885
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mitochondrion. 2016 09 ;30:67-77. Epub 2016 Jun 30. PMID: 27374852
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemopreventive
Additional Keywords : Isothiocyanates
[+]

Inhibition of phosphatidylinositide 3-kinase ameliorates antiproliferation by benzyl isothiocyanate in human colon cancer cells.Jan 08, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 09 9 ;491(1):209-216. Epub 2017 Jul 13. PMID: 28712871
Article Published Date : Jan 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Cancers: Drug Resistant, Colon Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
Additional Keywords : Isothiocyanates
[+]

Isothiocyanates suppress the invasion and metastasis of tumors.Sep 07, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Sep 8 ;8(38):63949-63962. Epub 2017 Jul 12. PMID: 28969043
Article Published Date : Sep 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Molecular mechanisms of the anti-cancer effects of isothiocyanates from cruciferous vegetables in bladder cancer.Jan 28, 2020

Pubmed Data : Molecules. 2020 Jan 29 ;25(3). Epub 2020 Jan 29. PMID: 32013065
Article Published Date : Jan 28, 2020
Study Type : Review
Additional Links
Substances : Benzyl isothiocyanate , Cruciferous Vegetables, Isothiocyanates, Phenethyl isothiocyanate, Sulforaphane
Diseases : Bladder Cancer
Pharmacological Actions : Chemopreventive
[+]

Nephroprotective effects of benzyl isothiocyanate and resveratrol against cisplatin-induced oxidative stress and inflammation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1268. Epub 2018 Nov 21. PMID: 30524274
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Resveratrol
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
Additional Keywords : Natural Substance/Drug Synergy
[+]

Phenethyl isothiocyanate and Benzyl isothiocyanate inhibit human melanoma A375.S2 cell migration and invasion.Jan 10, 2017

Pubmed Data : Anticancer Res. 2017 11 ;37(11):6223-6234. PMID: 29061805
Article Published Date : Jan 10, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancer Metastasis, Melanoma
Pharmacological Actions : Anti-metastatic
Additional Keywords : Isothiocyanates
[+]

Sulforaphane and benzyl isothiocyanate exhibit antibacterial activity against gram-positive and gram-negative bacteria.Jun 01, 2009

Pubmed Data : J Appl Microbiol. 2009 Jun;106(6):2086-95. Epub 2009 Mar 9. PMID: 19291240
Article Published Date : Jun 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Sulforaphane
Diseases : Bacterial Infections and Mycoses, Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Synergistic action of benzyl isothiocyanate and sorafenib in a nanoparticle delivery system for enhanced triple-negative breast cancer treatment.Apr 25, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2024 Apr 26 ;16(9). Epub 2024 Apr 26. PMID: 38730647
Article Published Date : Apr 25, 2024
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Synergistic effects of benzyl isothiocyanate and resveratrol against Listeria monocytogenes and their application in chicken meat preservation.Aug 31, 2023

Pubmed Data : Food Chem. 2023 Sep 1 ;419:135984. Epub 2023 Mar 23. PMID: 37044056
Article Published Date : Aug 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Resveratrol
Diseases : Foodborne Pathogens: Prevention/Food Preservation, Listeria Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]

The current study suggests that benzyl isothiocyanate could be an alternative to antibiotics.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2024 ;19(5):e0303490. Epub 2024 May 16. PMID: 38753636
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
[+]

This study suggests that benzyl isothiocyanate induced significant reductions in the viability of liver cancer cell lines.Jan 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 11 15 ;7(46):75749-75762. PMID: 27716619
Article Published Date : Jan 14, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12.Jun 19, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Jun 20 ;9(1):8866. Epub 2019 Jun 20. PMID: 31222108
Article Published Date : Jun 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative

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