Betel

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17 Diseases Researched for Betel

Name	AC	CK
Arthritis	1	2
Candida Albicans	2	2
Ehrlich carcinoma	1	2
Bacterial Infections: Resistance/Biofilm Formation	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Cancers: Drug Resistant	1	1
Cardiovascular Diseases	1	1
Colon Cancer	1	1
DNA damage	1	1
Escherichia coli Infections	1	1
Hyperuricemia	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Oxidative Stress	1	1
Pancreatic Cancer	1	1
Prostate Cancer	1	1
Pseudomonas aeruginosa	1	1
Staphylococcus aureus infection	1	1

18 Pharmacological Actions Researched for Betel

Name	AC	CK
Antiproliferative	4	5
Apoptotic	4	4
Anti-Bacterial Agents	2	2
Anti-Inflammatory Agents	1	2
Antifungal Agents	2	2
Antioxidants	2	2
Cell cycle arrest	2	2
Interleukin-1 beta downregulation	1	2
Postaglandin PGE2 downregulation	1	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	2
Anti-Apoptotic	1	1
Anti-metastatic	1	1
Anticarcinogenic Agents	1	1
Antineoplastic Agents	1	1
Cardioprotective	1	1
Chemosensitizer	1	1
Enzyme Inhibitors	1	1
Xanthine oxidase inhibitor	1	1

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Betel Research

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[+]

Inhibitory potential of Hydroxychavicol on Ehrlich ascites carcinoma model.May 31, 2020

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Pubmed Data : Nat Prod Res. 2020 Jun ;34(11):1591-1596. Epub 2018 Nov 23. PMID: 30470141

Article Published Date : May 31, 2020

Study Type : Animal Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Ehrlich carcinoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

[+]

Modulation of Th1/Th2 cytokines and inflammatory mediators by hydroxychavicol in adjuvant induced arthritic tissues.Dec 31, 2009

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Pubmed Data : Cytokine. 2010 Jan ;49(1):114-21. Epub 2009 Sep 25. PMID: 19782577

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Antioxidant activity of eugenol in Piper betel leaf extract.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Family Med Prim Care. 2020 Jan ;9(1):327-331. Epub 2020 Jan 28. PMID: 32110613

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Betel, Eugenol

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Ethyl acetate extract of mature betel leaf exhibited good anticandidal activity than that of tulsi and fluconazole.Aug 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Oral Maxillofac Pathol. 2019 Sep-Dec;23(3):333-337. PMID: 31942110

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Basil, Betel

Diseases : Candida Albicans

Pharmacological Actions : Antifungal Agents

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Hydroxychavicol from Piper betle induces apoptosis, cell cycle arrest, and inhibits epithelial-mesenchymal transition in pancreatic cancer cells.Jul 31, 2019

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Pubmed Data : Biochem Pharmacol. 2019 Aug ;166:274-291. Epub 2019 May 31. PMID: 31154000

Article Published Date : Jul 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Betel

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Hydroxychavicol induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells.Feb 14, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Zhejiang Univ Sci B. 2021 Feb 15 ;22(2):112-122. PMID: 33615752

Article Published Date : Feb 14, 2021

Study Type : In Vitro Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Hydroxychavicol inhibits prostate cancer through ROS-driven DNA damage and apoptosis.Sep 30, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Appl Pharmacol. 2014 Oct 1 ;280(1):86-96. Epub 2014 Jul 23. PMID: 25064160

Article Published Date : Sep 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Prostate Cancer

Pharmacological Actions : Apoptotic

[+]

Hydroxychavicol sensitizes imatinib-resistant chronic myelogenous leukemia cells to TRAIL-induced apoptosis.Dec 31, 2018

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Pubmed Data : Anticancer Drugs. 2019 02 ;30(2):167-178. PMID: 30418193

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Hydroxychavicol, a key ingredient of Piper betle induces bacterial cell death by DNA damage and inhibition of cell division.Jan 19, 2018

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Pubmed Data : Free Radic Biol Med. 2018 05 20 ;120:62-71. Epub 2018 Mar 15. PMID: 29550331

Article Published Date : Jan 19, 2018

Study Type : In Vitro Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Bacterial Infections: Resistance/Biofilm Formation

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Plant Extracts

[+]

Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.Jun 30, 2009

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Pubmed Data : J Nat Med. 2009 Jul ;63(3):355-9. Epub 2009 Apr 22. PMID: 19387769

Article Published Date : Jun 30, 2009

Study Type : In Vitro Study

Additional Links

Substances : Betel, Polyphenols

Diseases : Hyperuricemia

Pharmacological Actions : Enzyme Inhibitors, Xanthine oxidase inhibitor

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Piper betle: recent review of antibacterial and antifungal properties.Apr 15, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2021 Apr 16 ;26(8). Epub 2021 Apr 16. PMID: 33923576

Article Published Date : Apr 15, 2021

Study Type : Review

Additional Links

Substances : Betel

Diseases : Candida Albicans, Escherichia coli Infections, Pseudomonas aeruginosa, Staphylococcus aureus infection

Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents

Additional Keywords : Plant Extracts

[+]

Strengthening antioxidant defense & cardio protection by Piper betle.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Heliyon. 2020 Jan ;6(1):e03041. Epub 2019 Dec 26. PMID: 31909246

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Betel

Diseases : Cardiovascular Diseases

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective

[+]

Turmeric, betel leaf and catechu prevent benzo(a)pyrene-induced chromosomal damage in human lymphocytes.Jan 01, 1994

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Pubmed Data : Cell Biol Int. 1994 Jan;18(1):21-7. PMID: 8186767

Article Published Date : Jan 01, 1994

Study Type : In Vitro Study

Additional Links

Substances : Acacia catechu, Betel, Curcumin

Diseases : Benzo[a]pyrene-induced Toxicity , DNA damage

Pharmacological Actions : Anticarcinogenic Agents

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 13 Abstracts with Betel Research

Limited to Members Only

Currently Available Sorting Options

Inhibitory potential of Hydroxychavicol on Ehrlich ascites carcinoma model.May 31, 2020

Modulation of Th1/Th2 cytokines and inflammatory mediators by hydroxychavicol in adjuvant induced arthritic tissues.Dec 31, 2009

Antioxidant activity of eugenol in Piper betel leaf extract.Dec 31, 2019

Ethyl acetate extract of mature betel leaf exhibited good anticandidal activity than that of tulsi and fluconazole.Aug 31, 2019

Hydroxychavicol from Piper betle induces apoptosis, cell cycle arrest, and inhibits epithelial-mesenchymal transition in pancreatic cancer cells.Jul 31, 2019

Hydroxychavicol induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells.Feb 14, 2021

Hydroxychavicol inhibits prostate cancer through ROS-driven DNA damage and apoptosis.Sep 30, 2014

Hydroxychavicol sensitizes imatinib-resistant chronic myelogenous leukemia cells to TRAIL-induced apoptosis.Dec 31, 2018

Hydroxychavicol, a key ingredient of Piper betle induces bacterial cell death by DNA damage and inhibition of cell division.Jan 19, 2018

Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.Jun 30, 2009

Piper betle: recent review of antibacterial and antifungal properties.Apr 15, 2021

Strengthening antioxidant defense & cardio protection by Piper betle.Dec 31, 2019

Turmeric, betel leaf and catechu prevent benzo(a)pyrene-induced chromosomal damage in human lymphocytes.Jan 01, 1994

Betel Related Articles

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Betel

View the Evidence:
13 Abstracts with Betel Research