Bisdemethoxycurcumin

Name	AC	CK
Lipopolysaccharide-Induced Toxicity	6	13
Alzheimer's Disease	3	12
Glioblastoma	2	12
Lung Cancer	6	10
Inflammation	4	8
Non-Small-Cell Lung Carcinoma	2	6
Glioma	1	5
Carcinoma: Non-Small-Cell Lung	4	4
Arthritis	1	3
High Fat Diet	2	3
Obesity	3	3
Oral Cancer	2	3
Oxidative Stress	2	3
Rheumatoid Arthritis	1	3
Atherosclerosis	1	2
Atopic Dermatitis	1	2
Bladder Cancer	1	2
Cancers: Drug Resistant	2	2
Cardiovascular Diseases	2	2
Chemotherapy-Induced Toxicity: Cisplatin	2	2
Chronic Kidney Disease (CKD)	1	2
Colitis	1	2
Diabetes Mellitus: Type 2	2	2
Food Allergies	1	2
Gastric Cancer	1	2
Gastric Ulcer	1	2
Hyperglycemia	1	2
Influenza	1	2
Kidney Fibrosis	1	2
Lung Cancer: Metastatic	2	2
Lung Injury: Acute	1	2
Mitochondrial Dysfunction	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Osteosarcoma	2	2
Prostate Cancer	2	2
Radiotherapy	1	2
Tumors	1	2
Allergic Rhinitis	1	1
Allergies	1	1
Cancer Metastasis	1	1
Cancers: All	1	1
Cancers: Multi-Drug Resistant	1	1
Cervical Cancer	1	1
Chemotherapy-Induced Toxicity: Gentamicin	1	1
Coronavirus Infection	1	1
Diabetes Mellitus: Type 2: Prevention	1	1
Dyslipidemias	1	1
Ebola	1	1
Endothelial Dysfunction	1	1
Fructose-Induced Toxicity	1	1
Glioblastoma Multiforme	1	1
High Fructose Diet	1	1
Insect Bites: Repellent	1	1
Leukemia	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Liver Cancer	1	1
Ovarian Cancer	1	1
Pancreatic Cancer	1	1
Parkinson's Disease	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Apoptotic	15	22
Antiproliferative	12	21
Anti-Inflammatory Agents	10	16
Neuroprotective Agents	5	16
Anti-metastatic	8	12
Antioxidants	8	11
Cell cycle arrest	5	9
NF-kappaB Inhibitor	6	9
Autophagy Up-regulation	6	7
Renoprotective	3	6
Chemotherapeutic	3	5
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	5
Antiviral Agents	3	4
Chemosensitizer	3	4
Gastroprotective	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	4	4
Cyclooxygenase 2 Inhibitors	1	3
Immunomodulatory	2	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	3
Nrf2 activation	2	3
Alpha-amylase inhibitor	1	2
Anti-Adipogenic	2	2
Anti-Allergic Agents	1	2
Anti-Anxiety Agents	1	2
Anti-Fibrotic	1	2
Anti-Ulcer Agents	1	2
Anticarcinogenic Agents	1	2
Antineoplastic Agents	2	2
Bcl-2 protein down-regulation	2	2
Cardioprotective	2	2
Caspase-9 Activation	2	2
Chemoprotective Agents	2	2
Gastrointestinal Agents	1	2
Hepatoprotective	1	2
Hypoglycemic Agents	1	2
Hypolipidemic	1	2
Proton Pump Inhibitor	1	2
Radioprotective	1	2
Acetylcholinesterase Inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Anti-Apoptotic	1	1
Caspase-3 Activation	1	1
Caspase-8 activation	1	1
Cyclin D1 Down-Regulation	1	1
Enzyme Inhibitors: Pancreatic Amylase	1	1
Glucose transporter-2 (GLUT2) expression down-regulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Heme oxygenase-1 up-regulation	1	1
Insect Repellents	1	1
Interleukin-6 Downregulation	1	1
Interleukin-8 downregulation	1	1
Radiosensitizer	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin pathway down-regulation	1	1

[+]

Bisdemethoxycurcumin loaded H-ferritin-nanocages mediate the regulation of inflammation in Alzheimer's disease.Aug 16, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Aug 17 ;23(16). Epub 2022 Aug 17. PMID: 36012501

Article Published Date : Aug 16, 2022

Study Type : Human Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Oral treatment with micellar curcuminoids led to quantifiable concentrations of total curcuminoids in glioblastomas.Jun 23, 2016

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Pubmed Data : Nutr Cancer. 2016 Jun 24:1-6. Epub 2016 Jun 24. PMID: 27340742

Article Published Date : Jun 23, 2016

Study Type : Human Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Curcuminoids, Demethoxycurcumin

Diseases : Glioblastoma

[+]

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

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Pubmed Data : In Vivo. 2015 11-12;29(6):711-728. PMID: 26546528

Article Published Date : Jan 10, 2015

Study Type : Human In Vitro

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Lung Cancer, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest

Additional Keywords : Gene Expression Regulation

[+]

The anti-cancer effect of four curcumin analogues on human glioma cells.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2021 ;14:4345-4359. Epub 2021 Aug 4. PMID: 34376999

Article Published Date : Dec 31, 2020

Study Type : Human In Vitro

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Curcuminoids, Demethoxycurcumin

Diseases : Glioma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Bisdemethoxycurcumin ameliorates adjuvant-induced arthritis by suppressing inflammatory reactions and macrophage migration.Jan 04, 2024

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Pubmed Data : Chem Biol Interact. 2024 Jan 5 ;387:110822. Epub 2023 Dec 5. PMID: 38056805

Article Published Date : Jan 04, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Arthritis, Inflammation, Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor

[+]

Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Pharm Res. 2020 Apr 4. Epub 2020 Apr 4. PMID: 32248350

Article Published Date : Apr 03, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin, Dihydrocurcumin, Tetrahydrocurcumin

Diseases : Influenza

Pharmacological Actions : Antiviral Agents

[+]

Bisdemethoxycurcumin alleviates dextran sodium sulfate-induced colitis.Oct 06, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2022 Oct 7 ;11(10). Epub 2022 Oct 7. PMID: 36290717

Article Published Date : Oct 06, 2022

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

[+]

Bisdemethoxycurcumin alleviates LPS-induced acute lung injury.Nov 19, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Pharmacol Toxicol. 2023 Nov 20 ;24(1):63. Epub 2023 Nov 20. PMID: 37986186

Article Published Date : Nov 19, 2023

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Bisdemethoxycurcumin attenuated gastric adenocarcinoma growth by inducing mitochondrial dysfunction.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2015 Jan ;9(1):270-274. Epub 2014 Nov 7. PMID: 25435973

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Gastric Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Dose Response

[+]

Bisdemethoxycurcumin attenuated renal injury via activation of Keap1/Nrf2 pathway in high-fat diet.Jul 01, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Jul 2 ;23(13). Epub 2022 Jul 2. PMID: 35806399

Article Published Date : Jul 01, 2022

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Chronic Kidney Disease (CKD), High Fat Diet, Oxidative Stress

Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective

[+]

Bisdemethoxycurcumin attenuates lipopolysaccharide-induced intestinal damag.Oct 18, 2021

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Pubmed Data : J Anim Sci. 2021 Oct 19. Epub 2021 Oct 19. PMID: 34664650

Article Published Date : Oct 18, 2021

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective

[+]

Bisdemethoxycurcumin attenuates OVA-induced food allergy by inhibiting the MAPK and NF-κB signaling pathways.May 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2022 Jun ;23(6):401. Epub 2022 Apr 20. PMID: 35619631

Article Published Date : May 31, 2022

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Food Allergies

Pharmacological Actions : Anti-Allergic Agents

[+]

Bisdemethoxycurcumin has an anxiolytic effect against lead-induced anxiety and restores the renal injuries induced by lead exposure.Jan 22, 2021

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Pubmed Data : J Trace Elem Med Biol. 2021 Jan 23 ;65:126722. Epub 2021 Jan 23. PMID: 33524682

Article Published Date : Jan 22, 2021

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Pharmacological Actions : Anti-Anxiety Agents, Neuroprotective Agents, Renoprotective

Problem Substances : Lead

[+]

Bisdemethoxycurcumin in combination with α-PD-L1 antibody may be promising for bladder cancer patients.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2017 ;10:2675-2683. Epub 2017 May 22. PMID: 28579805

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Bladder Cancer

Pharmacological Actions : Chemotherapeutic, Immunomodulatory

[+]

Bisdemethoxycurcumin induces cell apoptosis and inhibits human brain glioblastoma.Jan 03, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Jan 4 ;23(1). Epub 2022 Jan 4. PMID: 35008959

Article Published Date : Jan 03, 2022

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Bisdemethoxycurcumin may act as a novel and potent therapeutic agent against NAFLD.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(2):e0147745. Epub 2016 Feb 16. PMID: 26881746

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Silymarin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Natural Substance Synergy

[+]

Bisdemethoxycurcumin protects against renal fibrosis.Mar 14, 2019

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Pubmed Data : Eur J Pharmacol. 2019 Mar 15 ;847:26-31. Epub 2019 Jan 17. PMID: 30660576

Article Published Date : Mar 14, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

[+]

Bisdemethoxycurcumin protects small intestine from lipopolysaccharide-induced mitochondrial dysfunction.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:9927864. Epub 2021 Nov 9. PMID: 34795844

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Mitochondrial Dysfunction

Pharmacological Actions : Antioxidants, Gastroprotective

[+]

Bisdemethoxycurcumin suppresses the progression of atherosclerosis.Jun 07, 2023

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Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Jun 8. Epub 2023 Jun 8. PMID: 37289282

Article Published Date : Jun 07, 2023

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Atherosclerosis

Pharmacological Actions : Hypolipidemic

[+]

Curcumin compares favorably with bisdemethoxycurcumin in a gastric ulcer model system. Apr 01, 2009

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Pubmed Data : Phytomedicine. 2009 Apr;16(4):342-51. Epub 2009 Feb 1. PMID: 19188055

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin

Diseases : Gastric Ulcer, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Ulcer Agents, Proton Pump Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer.May 01, 2018

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Pubmed Data : Environ Toxicol. 2018 May 2. Epub 2018 May 2. PMID: 29717538

Article Published Date : May 01, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcuminoids, Demethoxycurcumin

Diseases : Oral Cancer

Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

[+]

Curcuminoids inhibit chemically-induced tumor promotion.Oct 01, 1995

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Pubmed Data : Carcinogenesis. 1995 Oct;16(10):2493-7. PMID: 7586157

Article Published Date : Oct 01, 1995

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Curcuminoids, Demethoxycurcumin, Tetrahydrocurcumin

Diseases : Tumors

Pharmacological Actions : Anticarcinogenic Agents

[+]

Dietary bisdemethoxycurcumin supplementation attenuates lipopolysaccharide-induced damages on intestinal redox potential.Apr 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Poult Sci. 2021 May ;100(5):101061. Epub 2021 Feb 19. PMID: 33756250

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Antioxidants

[+]

Improvement in serum amylase and glucose levels after administration of bisdemethoxycurcumin from Curcuma longa and limonoids from Azadirachta indica.Feb 25, 2021

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Pubmed Data : J Food Biochem. 2021 Feb 26:e13674. Epub 2021 Feb 26. PMID: 33634871

Article Published Date : Feb 25, 2021

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Neem

Diseases : Hyperglycemia

Pharmacological Actions : Alpha-amylase inhibitor, Hypoglycemic Agents

[+]

Inhibitory effect of bisdemethoxycurcumin on DNCB-induced atopic dermatitis.Dec 29, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2022 Dec 30 ;28(1). Epub 2022 Dec 30. PMID: 36615486

Article Published Date : Dec 29, 2022

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Atopic Dermatitis

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Treatment of radiation-induced brain injury with bisdemethoxycurcumin.Jan 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neural Regen Res. 2023 Feb ;18(2):416-421. PMID: 35900439

Article Published Date : Jan 31, 2023

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Radiotherapy

Pharmacological Actions : Neuroprotective Agents, Radioprotective

[+]

Bisdemethoxycurcumin from Curcuma longa rhizome is a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes.Dec 14, 2012

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Pubmed Data : Food Chem. 2012 Dec 15 ;135(4):2638-42. Epub 2012 Jul 13. PMID: 22980852

Article Published Date : Dec 14, 2012

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Enzyme Inhibitors: Pancreatic Amylase

[+]

A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells.Oct 11, 2020

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Pubmed Data : J Ethnopharmacol. 2020 Oct 12:113467. Epub 2020 Oct 12. PMID: 33058923

Article Published Date : Oct 11, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcuminoids, Turmeric

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Natural Substance Synergy

[+]

Antioxidant activity of curcuminoids.Feb 12, 2019

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Pubmed Data : Phys Chem Chem Phys. 2019 Feb 13 ;21(7):3752-3760. PMID: 30702098

Article Published Date : Feb 12, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcuminoids, Demethoxycurcumin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory.May 04, 2020

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Pubmed Data : Eur J Pharmacol. 2020 May 5 ;874:173026. Epub 2020 Feb 20. PMID: 32088177

Article Published Date : May 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents

[+]

Bisdemethoxycurcumin augments docetaxel efficacy for treatment of prostate cancer.Dec 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2024 ;47(8):1437-1446. PMID: 39143009

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Prostate Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Bcl-2 protein down-regulation

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

Bisdemethoxycurcumin enhances the sensitivity of non-small cell lung cancer cells to icotinib.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Biol Sci. 2020 ;16(9):1536-1550. Epub 2020 Mar 5. PMID: 32226300

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

[+]

Bisdemethoxycurcumin enhances X-ray-induced apoptosis possibly through p53/Bcl-2 pathway.Feb 28, 2017

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Pubmed Data : Mutat Res. 2017 Mar ;815:1-5. Epub 2017 Jan 11. PMID: 28283087

Article Published Date : Feb 28, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Leukemia: T-cell acute Lymphoblastic

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Radiosensitizer, Tumor Suppressor Protein p53 Upregulation

[+]

Bisdemethoxycurcumin exerts a cell-protective effect via JAK2/STAT3 signalling in a rotenone-induced Parkinson's disease model in vitro. Jun 17, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Folia Histochem Cytobiol. 2020 Jun 18. Epub 2020 Jun 18. PMID: 32557525

Article Published Date : Jun 17, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Bisdemethoxycurcumin induced cell apoptosis through multiple signal pathways such as extrinsic, intrinsic and ES tress pathway.Sep 14, 2015

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Pubmed Data : Environ Toxicol. 2015 Sep 15. Epub 2015 Sep 15. PMID: 26370218

Article Published Date : Sep 14, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Lung Cancer

Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, Cell cycle arrest

[+]

Bisdemethoxycurcumin induced DNA damage and condension and affected DNA repair proteins in NCI-H460 cells in vitro.Aug 29, 2015

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Pubmed Data : Environ Toxicol. 2015 Aug 30. Epub 2015 Aug 30. PMID: 26332341

Article Published Date : Aug 29, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Carcinoma: Non-Small-Cell Lung

[+]

Bisdemethoxycurcumin inhibits hepatocellular carcinoma proliferation.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2020 ;14:993-1001. Epub 2020 Mar 5. PMID: 32184568

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative

[+]

Bisdemethoxycurcumin inhibits VEGF-induced HUVECs proliferation, migration and invasion.Jun 20, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2022 Jun 21. Epub 2022 Jun 21. PMID: 35732438

Article Published Date : Jun 20, 2022

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Endothelial Dysfunction

Pharmacological Actions : Antiproliferative , Autophagy Up-regulation, Cell cycle arrest, Cyclin D1 Down-Regulation

[+]

Bisdemethoxycurcumin inhibits Wnt/β-catenin pathway by increasing WIF-1 expression, which subsequently leads to suppression of TGF-β1-induced EMT migration.Dec 31, 1969

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Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer, Lung Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, Wnt/β-catenin pathway down-regulation

[+]

Bisdemethoxycurcumin is a potential agent for reducing gentamicin-induced ototoxicity.Apr 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : In Vivo. 2022 May-Jun;36(3):1095-1105. PMID: 35478148

Article Published Date : Apr 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Chemoprotective Agents

[+]

Bisdemethoxycurcumin is able to sensitize cisplatin-resistant NSCLC cells to chemotherapeutic agents.Jul 03, 2017

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Pubmed Data : Apoptosis. 2017 Jul 4. Epub 2017 Jul 4. PMID: 28677094

Article Published Date : Jul 03, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cancers: Multi-Drug Resistant, Lung Cancer

Pharmacological Actions : Chemosensitizer

[+]

Bisdemethoxycurcumin may have potential as a novel anti-metastasis agent for the treatment of human cervical cancer.Jun 30, 2018

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Pubmed Data : Anticancer Res. 2018 Jul ;38(7):3989-3997. PMID: 29970522

Article Published Date : Jun 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cancer Metastasis, Cervical Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

[+]

Bisdemethoxycurcumin partially offsets the chemoresistance induced by gemcitabine and produces apoptosis in PANC-1 cells.Nov 09, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Nov 10. Epub 2016 Nov 10. PMID: 27845899

Article Published Date : Nov 09, 2016

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cancers: Drug Resistant, Pancreatic Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Bisdemethoxycurcumin possessed favorable cardioprotection in a Nrf2/HO-1-dependent manner.Sep 15, 2019

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Pubmed Data : Chem Res Toxicol. 2019 Sep 16 ;32(9):1871-1879. Epub 2019 Aug 22. PMID: 31402651

Article Published Date : Sep 15, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cardiovascular Diseases

Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

Bisdemethoxycurcumin sensitizes the response of cisplatin resistant non-small cell lung carcinoma cell lines.Jul 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Biochem. 2022 Aug ;106:109003. Epub 2022 Mar 26. PMID: 35346827

Article Published Date : Jul 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Autophagy Up-regulation

[+]

Bisdemethoxycurcumin serves as a therapeutic medicine to suppress ovarian cancer.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 ;6:28773. Epub 2016 Jun 28. PMID: 27349797

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antioxidants, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Dose Response

[+]

Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme.Jun 22, 2022

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Pubmed Data : Environ Toxicol. 2022 Jun 23. Epub 2022 Jun 23. PMID: 35735092

Article Published Date : Jun 22, 2022

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Glioblastoma Multiforme

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion.Nov 30, 2022

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Pubmed Data : Oncol Rep. 2022 Dec ;48(6). Epub 2022 Oct 12. PMID: 36222295

Article Published Date : Nov 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Osteosarcoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Caspase-9 Activation, Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor

[+]

Bisdemethoxycurcumin suppresses the expression of TNF α, IL 8, and IL 6 by inhibiting the NF κB and mitogen activated protein kinase signalling pathways.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):630-635. Epub 2017 Oct 20. PMID: 29115448

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin and natural derivatives inhibit ebola viral proteins.Nov 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacognosy Res. 2017 Dec ;9(Suppl 1):S15-S22. PMID: 29333037

Article Published Date : Nov 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin

Diseases : Ebola

Pharmacological Actions : Antiviral Agents

Additional Keywords : Antiviral Agents, Bisdemethoxycurcumin, CURCUMIN, Demethoxycurcumin, Ebola

[+]

Curcumin, dimethoxy Curcumin and bisdemethoxycurcumin could be used as a potential anticancer agent in human oral cancer.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2018 ;46(5):1145-1168. Epub 2018 Jul 5. PMID: 29976081

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Curcuminoids

Diseases : Oral Cancer

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

[+]

Curcuminoid extracts and nanoemulsions prepared from Curcuma longa linnaeus could inhibit lung cancer cells.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Nanomedicine. 2015 ;10:5059-80. Epub 2015 Aug 5. PMID: 26345201

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin

Diseases : Lung Cancer, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Apoptotic, Cell cycle arrest

[+]

Curcuminoids have anti-cholinesterase and anti-diabetic activities.Mar 12, 2017

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Pubmed Data : Nat Prod Res. 2017 Mar 13:1-4. Epub 2017 Mar 13. PMID: 28287280

Article Published Date : Mar 12, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcuminoids, Demethoxycurcumin, Turmeric

Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2

Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Antioxidants

[+]

Curcuminoids: Implication for inflammation and oxidative stress in cardiovascular diseases.Mar 03, 2019

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Pubmed Data : Phytother Res. 2019 Mar 4. Epub 2019 Mar 4. PMID: 30834628

Article Published Date : Mar 03, 2019

Study Type : Review

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin

Diseases : Cardiovascular Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective

[+]

Dietary bisdemethoxycurcumin suppresses Wilms' tumor 1 and CD34 protein expressions in KG-1a leukemic stem cells.Apr 06, 2019

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Pubmed Data : Nutr Cancer. 2019 Apr 7:1-12. Epub 2019 Apr 7. PMID: 30955364

Article Published Date : Apr 06, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Leukemia

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Cancer Stem Cells

[+]

Guava leaf and turmeric extracts might be useful to reduce the risks of obesity, diabetes or dyslipidemia from excessive fructose intake.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2015 ;20(9):17393-404. Epub 2015 Sep 18. PMID: 26393568

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Guava, Quercetin, Turmeric

Diseases : Diabetes Mellitus: Type 2: Prevention, Dyslipidemias, Fructose-Induced Toxicity , High Fructose Diet, Obesity

Pharmacological Actions : Glucose transporter-2 (GLUT2) expression down-regulation, Glucose transporter-5 (GLUT5) expression down-regulation

Additional Keywords : Plant Extracts

[+]

In a dose response bioassay, ar-turmerone showed significantly higher biting deterrence than DEET at all the dosages. Jun 22, 2015

Click here to read the entire abstract

Pubmed Data : J Med Entomol. 2015 Jun 23. Epub 2015 Jun 23. PMID: 26336212

Article Published Date : Jun 22, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin, Turmeric, Turmerones

Diseases : Insect Bites: Repellent

Pharmacological Actions : Insect Repellents

Additional Keywords : Essential Oils, Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Inhibitory effects of bisdemethoxycurcumin on mast cell-mediated allergic diseases.Nov 30, 2018

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Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:182-189. Epub 2018 Oct 10. PMID: 30316076

Article Published Date : Nov 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Allergic Rhinitis, Allergies

Pharmacological Actions : Immunomodulatory

[+]

Investigating the mechanisms of bisdemethoxycurcumin in ulcerative colitis.Dec 20, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2022 Dec 21 ;28(1). Epub 2022 Dec 21. PMID: 36615264

Article Published Date : Dec 20, 2022

Study Type : Review

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

The combination of curcuminoids could be used as a novel target for the treatment of osteosarcoma.Mar 02, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Med Ther. 2020 Mar 3 ;20(1):68. Epub 2020 Mar 3. PMID: 32126993

Article Published Date : Mar 02, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin

Diseases : Osteosarcoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Natural Substance Synergy

[+]

The demethoxy derivatives of curcumin exhibit greater differentiation suppression in 3T3-L1 adipocytes than curcumin.Jul 13, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2021 Jul 14 ;11(7). Epub 2021 Jul 14. PMID: 34356649

Article Published Date : Jul 13, 2021

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Demethoxycurcumin

Diseases : Obesity

Pharmacological Actions : Anti-Adipogenic

Additional Keywords : Anti-Obesity Agents

[+]

The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PeerJ. 2021 ;9:e11590. Epub 2021 Jul 19. PMID: 34322316

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Demethoxycurcumin

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

The present review discusses the findings on the anti-tumor effects of bisdemethoxycurcumin.Jan 10, 2017

Click here to read the entire abstract

Pubmed Data : J Cell Physiol. 2017 Jan 11. Epub 2017 Jan 11. PMID: 28075008

Article Published Date : Jan 10, 2017

Study Type : Review

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

These findings provided direct evidence that Bisdemethoxycurcumin inhibits 95D-cell migration and invasion.Oct 31, 2015

Click here to read the entire abstract

Pubmed Data : Mol Med Rep. 2015 Nov ;12(5):7603-8. Epub 2015 Sep 24. PMID: 26459909

Article Published Date : Oct 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Lung Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, Antiproliferative , Autophagy Up-regulation

[+]

These results indicate that bisdemethoxycurcumin-enriched turmeric extract could improve the cholinergic functions.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : SAGE Open Med. 2020 ;8:2050312120973499. Epub 2020 Nov 23. PMID: 33282298

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor

[+]

These results suggest that bisdemethoxycurcumin has the potential to prevent obesity.Jan 15, 2016

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2016 Jan 16. Epub 2016 Jan 16. PMID: 26777574

Article Published Date : Jan 15, 2016

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Anti-Adipogenic

Additional Keywords : Anti-Obesity Agents

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View the Evidence: 66 Abstracts with Bisdemethoxycurcumin Research

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Bisdemethoxycurcumin loaded H-ferritin-nanocages mediate the regulation of inflammation in Alzheimer's disease.Aug 16, 2022

Oral treatment with micellar curcuminoids led to quantifiable concentrations of total curcuminoids in glioblastomas.Jun 23, 2016

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

The anti-cancer effect of four curcumin analogues on human glioma cells.Dec 31, 2020

Bisdemethoxycurcumin ameliorates adjuvant-induced arthritis by suppressing inflammatory reactions and macrophage migration.Jan 04, 2024

Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

Bisdemethoxycurcumin alleviates dextran sodium sulfate-induced colitis.Oct 06, 2022

Bisdemethoxycurcumin alleviates LPS-induced acute lung injury.Nov 19, 2023

Bisdemethoxycurcumin attenuated gastric adenocarcinoma growth by inducing mitochondrial dysfunction.Dec 31, 2014

Bisdemethoxycurcumin attenuated renal injury via activation of Keap1/Nrf2 pathway in high-fat diet.Jul 01, 2022

Bisdemethoxycurcumin attenuates lipopolysaccharide-induced intestinal damag.Oct 18, 2021

Bisdemethoxycurcumin attenuates OVA-induced food allergy by inhibiting the MAPK and NF-κB signaling pathways.May 31, 2022

Bisdemethoxycurcumin has an anxiolytic effect against lead-induced anxiety and restores the renal injuries induced by lead exposure.Jan 22, 2021

Bisdemethoxycurcumin in combination with α-PD-L1 antibody may be promising for bladder cancer patients.Dec 31, 2016

Bisdemethoxycurcumin induces cell apoptosis and inhibits human brain glioblastoma.Jan 03, 2022

Bisdemethoxycurcumin may act as a novel and potent therapeutic agent against NAFLD.Dec 31, 2015

Bisdemethoxycurcumin protects against renal fibrosis.Mar 14, 2019

Bisdemethoxycurcumin protects small intestine from lipopolysaccharide-induced mitochondrial dysfunction.Dec 31, 2020

Bisdemethoxycurcumin suppresses the progression of atherosclerosis.Jun 07, 2023

Curcumin compares favorably with bisdemethoxycurcumin in a gastric ulcer model system. Apr 01, 2009

Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer.May 01, 2018

Curcuminoids inhibit chemically-induced tumor promotion.Oct 01, 1995

Dietary bisdemethoxycurcumin supplementation attenuates lipopolysaccharide-induced damages on intestinal redox potential.Apr 30, 2021

Improvement in serum amylase and glucose levels after administration of bisdemethoxycurcumin from Curcuma longa and limonoids from Azadirachta indica.Feb 25, 2021

Inhibitory effect of bisdemethoxycurcumin on DNCB-induced atopic dermatitis.Dec 29, 2022

Treatment of radiation-induced brain injury with bisdemethoxycurcumin.Jan 31, 2023

Bisdemethoxycurcumin from Curcuma longa rhizome is a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes.Dec 14, 2012

A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells.Oct 11, 2020

Antioxidant activity of curcuminoids.Feb 12, 2019

Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory.May 04, 2020

Bisdemethoxycurcumin augments docetaxel efficacy for treatment of prostate cancer.Dec 31, 2023

Bisdemethoxycurcumin enhances the sensitivity of non-small cell lung cancer cells to icotinib.Dec 31, 2019

Bisdemethoxycurcumin enhances X-ray-induced apoptosis possibly through p53/Bcl-2 pathway.Feb 28, 2017

Bisdemethoxycurcumin exerts a cell-protective effect via JAK2/STAT3 signalling in a rotenone-induced Parkinson's disease model in vitro. Jun 17, 2020

Bisdemethoxycurcumin induced cell apoptosis through multiple signal pathways such as extrinsic, intrinsic and ES tress pathway.Sep 14, 2015

Bisdemethoxycurcumin induced DNA damage and condension and affected DNA repair proteins in NCI-H460 cells in vitro.Aug 29, 2015

Bisdemethoxycurcumin inhibits hepatocellular carcinoma proliferation.Dec 31, 2019

Bisdemethoxycurcumin inhibits VEGF-induced HUVECs proliferation, migration and invasion.Jun 20, 2022

Bisdemethoxycurcumin inhibits Wnt/β-catenin pathway by increasing WIF-1 expression, which subsequently leads to suppression of TGF-β1-induced EMT migration.Dec 31, 1969

Bisdemethoxycurcumin is a potential agent for reducing gentamicin-induced ototoxicity.Apr 30, 2022

Bisdemethoxycurcumin is able to sensitize cisplatin-resistant NSCLC cells to chemotherapeutic agents.Jul 03, 2017

Bisdemethoxycurcumin may have potential as a novel anti-metastasis agent for the treatment of human cervical cancer.Jun 30, 2018

Bisdemethoxycurcumin partially offsets the chemoresistance induced by gemcitabine and produces apoptosis in PANC-1 cells.Nov 09, 2016

Bisdemethoxycurcumin possessed favorable cardioprotection in a Nrf2/HO-1-dependent manner.Sep 15, 2019

Bisdemethoxycurcumin sensitizes the response of cisplatin resistant non-small cell lung carcinoma cell lines.Jul 31, 2022

Bisdemethoxycurcumin serves as a therapeutic medicine to suppress ovarian cancer.Dec 31, 2015

Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme.Jun 22, 2022

Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion.Nov 30, 2022

Bisdemethoxycurcumin suppresses the expression of TNF α, IL 8, and IL 6 by inhibiting the NF κB and mitogen activated protein kinase signalling pathways.Dec 31, 2017

Curcumin and natural derivatives inhibit ebola viral proteins.Nov 30, 2017

Curcumin, dimethoxy Curcumin and bisdemethoxycurcumin could be used as a potential anticancer agent in human oral cancer.Dec 31, 2017

Curcuminoid extracts and nanoemulsions prepared from Curcuma longa linnaeus could inhibit lung cancer cells.Dec 31, 2014

Curcuminoids have anti-cholinesterase and anti-diabetic activities.Mar 12, 2017

Curcuminoids: Implication for inflammation and oxidative stress in cardiovascular diseases.Mar 03, 2019

Dietary bisdemethoxycurcumin suppresses Wilms' tumor 1 and CD34 protein expressions in KG-1a leukemic stem cells.Apr 06, 2019

Guava leaf and turmeric extracts might be useful to reduce the risks of obesity, diabetes or dyslipidemia from excessive fructose intake.Dec 31, 2014

In a dose response bioassay, ar-turmerone showed significantly higher biting deterrence than DEET at all the dosages. Jun 22, 2015

Inhibitory effects of bisdemethoxycurcumin on mast cell-mediated allergic diseases.Nov 30, 2018

Investigating the mechanisms of bisdemethoxycurcumin in ulcerative colitis.Dec 20, 2022

The combination of curcuminoids could be used as a novel target for the treatment of osteosarcoma.Mar 02, 2020

The demethoxy derivatives of curcumin exhibit greater differentiation suppression in 3T3-L1 adipocytes than curcumin.Jul 13, 2021

The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket.Dec 31, 2020

The present review discusses the findings on the anti-tumor effects of bisdemethoxycurcumin.Jan 10, 2017

These findings provided direct evidence that Bisdemethoxycurcumin inhibits 95D-cell migration and invasion.Oct 31, 2015

These results indicate that bisdemethoxycurcumin-enriched turmeric extract could improve the cholinergic functions.Dec 31, 2019

These results suggest that bisdemethoxycurcumin has the potential to prevent obesity.Jan 15, 2016

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Bisdemethoxycurcumin

View the Evidence:
66 Abstracts with Bisdemethoxycurcumin Research